- Boron neutron capture therapy for undifferentiated thyroid carcinoma: preliminary results with the combined use of BPA and BOPPM Viaggi
Department of Radiobiology, Constituyentes Atomic Center, Av del Libertador 8250, 1429 Buenos Aires, Argentina
Appl Radiat Isot 61:905-9. 2004..Two groups of mice received different total absorbed doses: 3.00 and 6.01 Gy, but no further improvement in the outcome was found compared to the previous results using BPA alone (4.3 Gy)...
- Selective uptake of p-borophenylalanine by undifferentiated thyroid carcinoma for boron neutron capture therapyM A Dagrosa
Division of Nuclear Biochemistry, Department of Radiobiology, National Atomic Energy Commission, Buenos Aires, Argentina
Thyroid 12:7-12. 2002..The present experimental results open the possibility of applying BNCT for the treatment of UTC...
- Biodistribution of p-borophenylalanine (BPA) in dogs with spontaneous undifferentiated thyroid carcinoma (UTC)M A Dagrosa
Department of Radiobiology, University of Buenos Aires, 1429 Buenos Aires, Argentina
Appl Radiat Isot 61:911-5. 2004..36 and 0.33. These ratios were related to the two histological patterns observed: homogeneous and heterogeneous tumors. We confirm the selective uptake of BPA by spontaneous UTC in dogs and plan to apply BNCT in the future...
- A new animal model for human undifferentiated thyroid carcinomaM Viaggi
Nuclear Biochemistry Division, Department of Radiobiology, National Atomic Energy Commission, Buenos Aires, Argentina
Thyroid 13:529-36. 2003..This work provides an animal model of UTC pheno- and genotypically similar to the original human tumor, which may be useful for exploring new therapeutic modalities...
- Influence of nicotinamide on the radiosensitivity of normal and goitrous thyroid in the ratM Agote
Department of Radiobiology, National Atomic Energy Commission and University of Buenos Aires School of Medicine, Argentina
Thyroid 11:1003-7. 2001..In conclusion, nicotinamide has a significant radiosensitizing effect to 131I both in normal and goitrous rats. This action is because of an increase in thyroid blood flow, which probably enhances tissue oxgenation...