Roxana Schillaci

Summary

Country: Argentina

Publications

  1. ncbi request reprint Autocrine/paracrine involvement of insulin-like growth factor-I and its receptor in chronic lymphocytic leukaemia
    Roxana Schillaci
    Instituto de Biologia y Medicina Experimental CONICET, Buenos Aires, Argentina
    Br J Haematol 130:58-66. 2005
  2. ncbi request reprint TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways
    Martín A Rivas
    Laboratory of Molecular Mechanisms of Carcinogenesis, Instituto de Biologia y Medicina Experimental, CONICET, Vuelta de Obligado 2490, Buenos Aires, C1428ADN, Argentina
    Exp Cell Res 314:509-29. 2008
  3. pmc Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
    Roxana Schillaci
    Instituto de Biología y Medicina Experimental IBYME, CONICET, Buenos Aires, Argentina
    BMC Cancer 12:74. 2012
  4. ncbi request reprint Insulin-like growth factor-1 receptor regulation in activated human T lymphocytes
    Maria Eugenia Segretin
    Instituto de Biologia y Medicina Experimental CONICET, Buenos Aires, Argentina
    Horm Res 59:276-80. 2003
  5. pmc Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth
    Franco Izzo
    Instituto de Biología y Medicina Experimental IBYME, CONICET, Vuelta de Obligado 2490, Buenos Aires, 1428 ADN, Argentina
    Breast Cancer Res 16:491. 2014
  6. ncbi request reprint [Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer]
    Mariana Salatino
    Instituto de Biologia y Medicina Experimental IByME CONICET, Buenos Aires, Argentina
    Medicina (B Aires) 64:129-34. 2004
  7. ncbi request reprint ErbB-2 nuclear function in breast cancer growth, metastasis and resistance to therapy
    Patricia V Elizalde
    Laboratory of Molecular Mechanisms of CarcinogenesisInstituto de Biología y Medicina Experimental, CONICET, Buenos Aires, Argentina
    Endocr Relat Cancer 23:T243-T257. 2016
  8. doi request reprint Inhibition of MHC-I by Brucella abortus is an early event during infection and involves EGFR pathway
    Lis N Velásquez
    Instituto de Medicina Experimental CONICET Academia Nacional de Medicina, Buenos Aires, Argentina
    Immunol Cell Biol . 2016
  9. ncbi request reprint Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway
    Roxana Schillaci
    Instituto de Biologia y Medicina Experimental, Consejo Nacional de Investigaciones Cientificas y Tecnicas de Argentina, Vuelta de Obligado 2490, Buenos Aires C1428ADN, Argentina
    J Immunol 176:3426-37. 2006
  10. ncbi request reprint Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor acti
    Mariana Salatino
    Laboratory of Molecular Mechanisms of Carcinogenesis, Instituto de Biología y Medicina Experimental IBYME, CONICET, Obligado 2490, Buenos Aires 1428, Argentina
    Oncogene 23:5161-74. 2004

Collaborators

  • Patricia V Elizalde
  • Guillermo H Giambartolomei
  • Martín A Rivas
  • Juan C Roa
  • Damasia Becu-Villalobos
  • Mariana Salatino
  • Cecilia J Proietti
  • Lis N Velásquez
  • Franco Izzo
  • Romina Carnevale
  • Eduardo H Charreau
  • Aldana Trotta
  • M Victoria Delpino
  • Maria Eugenia Segretin
  • M Ayelén Milillo
  • Roberto G Pozner
  • Paula Barrionuevo
  • M Florencia Mercogliano
  • Gloria Inurrigarro
  • Leandro Venturutti
  • Florencia Mercogliano
  • Leandro Cerchietti
  • Mercedes Tkach
  • Adolfo Iribarren
  • Alfredo A Molinolo
  • Isabel Frahm
  • Adriana Galeano
  • Alicia Roldán

Detail Information

Publications10

  1. ncbi request reprint Autocrine/paracrine involvement of insulin-like growth factor-I and its receptor in chronic lymphocytic leukaemia
    Roxana Schillaci
    Instituto de Biologia y Medicina Experimental CONICET, Buenos Aires, Argentina
    Br J Haematol 130:58-66. 2005
    ..This is the first demonstration of IGF-IR expression in a subgroup of CLL patients and of its antiapoptotic effects in vitro, highlighting the importance of this growth factor receptor as a possible therapeutic target in CLL...
  2. ncbi request reprint TNF alpha acting on TNFR1 promotes breast cancer growth via p42/P44 MAPK, JNK, Akt and NF-kappa B-dependent pathways
    Martín A Rivas
    Laboratory of Molecular Mechanisms of Carcinogenesis, Instituto de Biologia y Medicina Experimental, CONICET, Vuelta de Obligado 2490, Buenos Aires, C1428ADN, Argentina
    Exp Cell Res 314:509-29. 2008
    ..Our results reveal evidence for TNF alpha as a breast tumor promoter, and provide novel data for a future therapeutic approach using TNF alpha antagonists and NF-kappa B pharmacological inhibitors in established breast cancer treatment...
  3. pmc Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
    Roxana Schillaci
    Instituto de Biología y Medicina Experimental IBYME, CONICET, Buenos Aires, Argentina
    BMC Cancer 12:74. 2012
    ..In this study we assessed the clinical significance of ErbB-2 nuclear localization in primary invasive breast cancer. The reporting recommendations for tumor marker prognostic studies (REMARK) guidelines were used as reference...
  4. ncbi request reprint Insulin-like growth factor-1 receptor regulation in activated human T lymphocytes
    Maria Eugenia Segretin
    Instituto de Biologia y Medicina Experimental CONICET, Buenos Aires, Argentina
    Horm Res 59:276-80. 2003
    ..To investigate the kinetics of insulin-like growth factor-1 receptor (IGF-1R) expression in PHA-stimulated T lymphocytes...
  5. pmc Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth
    Franco Izzo
    Instituto de Biología y Medicina Experimental IBYME, CONICET, Vuelta de Obligado 2490, Buenos Aires, 1428 ADN, Argentina
    Breast Cancer Res 16:491. 2014
    ..The role of GATA3 in breast cancer as a tumor suppressor has been established, although insights into the mechanism of GATA3 expression loss are still required...
  6. ncbi request reprint [Type I insulin-like growth factor receptor antisense strategies in experimental breast cancer]
    Mariana Salatino
    Instituto de Biologia y Medicina Experimental IByME CONICET, Buenos Aires, Argentina
    Medicina (B Aires) 64:129-34. 2004
    ..Progesterone receptor expression or activity remained invariable. This is the first demonstration that breast cancer growth can be inhibited by direct in vivo administration of IGF-IR AS[S]ODN...
  7. ncbi request reprint ErbB-2 nuclear function in breast cancer growth, metastasis and resistance to therapy
    Patricia V Elizalde
    Laboratory of Molecular Mechanisms of CarcinogenesisInstituto de Biología y Medicina Experimental, CONICET, Buenos Aires, Argentina
    Endocr Relat Cancer 23:T243-T257. 2016
    ....
  8. doi request reprint Inhibition of MHC-I by Brucella abortus is an early event during infection and involves EGFR pathway
    Lis N Velásquez
    Instituto de Medicina Experimental CONICET Academia Nacional de Medicina, Buenos Aires, Argentina
    Immunol Cell Biol . 2016
    ..Immunology and Cell Biology advance online publication, 29 November 2016; doi:10.1038/icb.2016.111...
  9. ncbi request reprint Immunization with murine breast cancer cells treated with antisense oligodeoxynucleotides to type I insulin-like growth factor receptor induced an antitumoral effect mediated by a CD8+ response involving Fas/Fas ligand cytotoxic pathway
    Roxana Schillaci
    Instituto de Biologia y Medicina Experimental, Consejo Nacional de Investigaciones Cientificas y Tecnicas de Argentina, Vuelta de Obligado 2490, Buenos Aires C1428ADN, Argentina
    J Immunol 176:3426-37. 2006
    ..Immunization with these tumor immunogens imparted protection against parental tumor growth through activation of a specific immune response...
  10. ncbi request reprint Inhibition of in vivo breast cancer growth by antisense oligodeoxynucleotides to type I insulin-like growth factor receptor mRNA involves inactivation of ErbBs, PI-3K/Akt and p42/p44 MAPK signaling pathways but not modulation of progesterone receptor acti
    Mariana Salatino
    Laboratory of Molecular Mechanisms of Carcinogenesis, Instituto de Biología y Medicina Experimental IBYME, CONICET, Obligado 2490, Buenos Aires 1428, Argentina
    Oncogene 23:5161-74. 2004
    ..Our results for the first time demonstrated that breast cancer growth can be inhibited by direct in vivo administration of IGF-IR AS[S]ODNs...