Mandar A Aras

Summary

Publications

  1. pmc Redox regulation of intracellular zinc: molecular signaling in the life and death of neurons
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, 3500 Terrace St, Pittsburgh, PA 15261, USA
    Antioxid Redox Signal 15:2249-63. 2011
  2. pmc Protein kinase C regulation of neuronal zinc signaling mediates survival during preconditioning
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    J Neurochem 110:106-17. 2009
  3. pmc Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling
    Patrick T Redman
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Physiol 587:4393-404. 2009
  4. pmc Zn2+ regulates Kv2.1 voltage-dependent gating and localization following ischemia
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Eur J Neurosci 30:2250-7. 2009
  5. doi request reprint Assessment of cell viability in primary neuronal cultures
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Curr Protoc Neurosci . 2008

Collaborators

Detail Information

Publications5

  1. pmc Redox regulation of intracellular zinc: molecular signaling in the life and death of neurons
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, 3500 Terrace St, Pittsburgh, PA 15261, USA
    Antioxid Redox Signal 15:2249-63. 2011
    ..Thus, redox-sensitive proteins, like metallothioneins, may play a critical role in determining neuronal cell fate by regulating the localization and concentration of intracellular free Zn(2+)...
  2. pmc Protein kinase C regulation of neuronal zinc signaling mediates survival during preconditioning
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    J Neurochem 110:106-17. 2009
    ..These results indicate that neuronal Zn(2+) serves as an important, highly regulated signaling component responsible for the initiation of a neuroprotective pathway...
  3. pmc Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling
    Patrick T Redman
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Physiol 587:4393-404. 2009
    ..Kv2.1-encoded channels thus regulate neuronal survival by providing a converging input for two Zn(2+)-dependent signal transduction cascades...
  4. pmc Zn2+ regulates Kv2.1 voltage-dependent gating and localization following ischemia
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Eur J Neurosci 30:2250-7. 2009
    ..1 channel activity and localization following ischemia. The identification of Zn(2+) in mediating ischemic modulation of Kv2.1 may lead to a better understanding of cellular adaptive responses to injury...
  5. doi request reprint Assessment of cell viability in primary neuronal cultures
    Mandar A Aras
    Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Curr Protoc Neurosci . 2008
    ..Finally, the fifth assay details the measurement of luciferase expression as an indication of neuronal viability within a relatively small population of transfected neurons...