Li An

Summary

Publications

  1. pmc Spectral localization by imaging using multielement receiver coils
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 66:1-10. 2011
  2. pmc Pilot results of in vivo brain glutathione measurements in stroke patients
    Li An
    Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Cereb Blood Flow Metab 32:2118-21. 2012
  3. pmc Combination of multichannel single-voxel MRS signals using generalized least squares
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Magn Reson Imaging 37:1445-50. 2013
  4. pmc Multivoxel MR spectroscopy in acute ischemic stroke: comparison to the stroke protocol MRI
    Krishna A Dani
    Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Stroke 43:2962-7. 2012
  5. pmc (13) C MRS of human brain at 7 Tesla using [2-(13) C]glucose infusion and low power broadband stochastic proton decoupling
    Shizhe Li
    Magnetic Resonance Spectroscopy Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 75:954-61. 2016
  6. pmc N-acetyl-aspartyl-glutamate detection in the human brain at 7 Tesla by echo time optimization and improved Wiener filtering
    Li An
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 72:903-12. 2014
  7. doi request reprint Detection of glutamate, glutamine, and glutathione by radiofrequency suppression and echo time optimization at 7 tesla
    Li An
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 73:451-8. 2015
  8. pmc Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20814, USA
    J Magn Reson Imaging 30:263-70. 2009
  9. pmc Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation
    Níall Lally
    Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Magn Reson Imaging 43:88-98. 2016
  10. pmc Image-guided spatial localization of heterogeneous compartments for magnetic resonance
    Li An
    Section on Magnetic Resonance Spectroscopy, Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20854
    Med Phys 42:5278-86. 2015

Collaborators

  • Jun Shen
  • Carlos A Zarate
  • Shumin Wang
  • Yan Zhang
  • Níall Lally
  • Shizhe Li
  • Ningzhi Li
  • Krishna A Dani
  • Erica M Richards
  • Maria Ferraris Araneta
  • Allison C Nugent
  • Dipavo Banerjee
  • Jonathan P Roiser
  • David A Luckenbaugh
  • Mark J Niciu
  • Christopher S Johnson
  • Shao Yu
  • Steven Warach
  • Erica C Henning

Detail Information

Publications11

  1. pmc Spectral localization by imaging using multielement receiver coils
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 66:1-10. 2011
    ..This may be useful for obtaining spectra from relatively small stroke lesions or tumors. Phantom experiments and in vivo magnetic resonance spectroscopy of stroke patients have been performed to demonstrate this technique...
  2. pmc Pilot results of in vivo brain glutathione measurements in stroke patients
    Li An
    Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA
    J Cereb Blood Flow Metab 32:2118-21. 2012
    ..45 to 1.41). This technique can detect glutathione changes because of disease, and may be valuable in clinical trials of stroke and other neurological diseases...
  3. pmc Combination of multichannel single-voxel MRS signals using generalized least squares
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Magn Reson Imaging 37:1445-50. 2013
    ..To propose using the generalized least square (GLS) algorithm for combining multichannel single-voxel magnetic resonance spectroscopy (MRS) signals...
  4. pmc Multivoxel MR spectroscopy in acute ischemic stroke: comparison to the stroke protocol MRI
    Krishna A Dani
    Section on Stroke Diagnostics and Therapeutics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA
    Stroke 43:2962-7. 2012
    ..Few patients with stroke have been imaged with MR spectroscopy (MRS) within the first few hours after onset. We compared data from current MRI protocols to MRS in subjects with ischemic stroke...
  5. pmc (13) C MRS of human brain at 7 Tesla using [2-(13) C]glucose infusion and low power broadband stochastic proton decoupling
    Shizhe Li
    Magnetic Resonance Spectroscopy Core Facility, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 75:954-61. 2016
    ..The purpose of present work is to study the feasibility of in vivo (13) C MRS of human brain at 7 T using broadband low RF power proton decoupling...
  6. pmc N-acetyl-aspartyl-glutamate detection in the human brain at 7 Tesla by echo time optimization and improved Wiener filtering
    Li An
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 72:903-12. 2014
    ..To report enhanced signal detection for measuring N-acetyl-aspartyl-glutamate (NAAG) in the human brain at 7 Tesla by echo time (TE) -optimized point-resolved spectroscopy (PRESS) and improved Wiener filtering...
  7. doi request reprint Detection of glutamate, glutamine, and glutathione by radiofrequency suppression and echo time optimization at 7 tesla
    Li An
    National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Magn Reson Med 73:451-8. 2015
    ..49 ppm using a echo time (TE) -optimized PRESS pulse sequence and a novel J-suppression radiofrequency pulse...
  8. pmc Measurement of glutathione in normal volunteers and stroke patients at 3T using J-difference spectroscopy with minimized subtraction errors
    Li An
    National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland 20814, USA
    J Magn Reson Imaging 30:263-70. 2009
    ..To develop and optimize a (1)H magnetic resonance spectroscopy (MRS) method for measuring brain glutathione (GSH) levels...
  9. pmc Reliability of 7T (1) H-MRS measured human prefrontal cortex glutamate, glutamine, and glutathione signals using an adapted echo time optimized PRESS sequence: A between- and within-sessions investigation
    Níall Lally
    Experimental Therapeutics and Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    J Magn Reson Imaging 43:88-98. 2016
    ..However, the advent of novel pulse sequences and higher field magnetic resonance imaging (MRI) allows more precise resolution of overlapping glutamatergic signals, although the question of signal reliability remains undetermined...
  10. pmc Image-guided spatial localization of heterogeneous compartments for magnetic resonance
    Li An
    Section on Magnetic Resonance Spectroscopy, Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20854
    Med Phys 42:5278-86. 2015
    ..Here, the authors propose a novel method to address the issue of heterogeneous signal distribution within the localized compartments...
  11. pmc Spectral fitting using basis set modified by measured B0 field distribution
    Ningzhi Li
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA
    NMR Biomed 28:1707-15. 2015
    ..Published 2015. This article is a U.S. Government work and is in the public domain in the USA. ..