Varkha Agrawal

Summary

Publications

  1. pmc Platelet-activating factor: a role in preterm delivery and an essential interaction with Toll-like receptor signaling in mice
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, Illinois
    Biol Reprod 91:119. 2014
  2. pmc Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, Illinois, USA
    PLoS ONE 8:e63990. 2013
  3. pmc Gonadal and nongonadal FSHR and LHR dysfunction during lipopolysaccharide induced failure of blastocyst implantation in mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    J Assist Reprod Genet 29:163-73. 2012
  4. doi request reprint Lipopolysaccharide drives alternation of heat shock proteins and induces failure of blastocyst implantation in mouse
    Mukesh Kumar Jaiswal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Biol Reprod 88:162. 2013
  5. doi request reprint Lipopolysaccharide-induced modulation in the expression of progesterone receptor and estradiol receptor leads to early pregnancy loss in mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior 474 011, India
    Zygote 21:337-44. 2013
  6. doi request reprint Bacterial endotoxin (LPS)-induced DNA damage in preimplanting embryonic and uterine cells inhibits implantation
    Yogesh Kumar Jaiswal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Fertil Steril 91:2095-103. 2009
  7. doi request reprint Lipopolysaccharide induces alterations in ovaries and serum level of progesterone and 17β-estradiol in the mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Fertil Steril 95:1471-4. 2011
  8. pmc Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, IL
    Sci Rep 5:9410. 2015
  9. pmc Intrauterine infection and preterm labor
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, 2650 Ridge Avenue, Evanston, IL 60201, USA
    Semin Fetal Neonatal Med 17:12-9. 2012
  10. pmc Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor
    Yana Filipovich
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, IL
    Am J Obstet Gynecol 213:697.e1-10. 2015

Collaborators

  • Emmet Hirsch
  • Mukesh Kumar Jaiswal
  • Yogesh Kumar Jaiswal
  • Yana Filipovich
  • Xiaowu Qu
  • Susan E Crawford
  • Philip Fitchev
  • Jeremy Klein
  • Madan Mohan Chaturvedi

Detail Information

Publications11

  1. pmc Platelet-activating factor: a role in preterm delivery and an essential interaction with Toll-like receptor signaling in mice
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, Illinois
    Biol Reprod 91:119. 2014
    ..We conclude that PAF signaling plays an important role in bacterially induced preterm delivery. Furthermore, in addition to its cognate receptor, PAF signaling in peritoneal macrophages requires TLR4, MyD88, and TRIF. ..
  2. pmc Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, Illinois, USA
    PLoS ONE 8:e63990. 2013
    ..We conclude that SP-A acts via TLR2 to suppress TLR ligand-induced preterm delivery and inflammatory responses...
  3. pmc Gonadal and nongonadal FSHR and LHR dysfunction during lipopolysaccharide induced failure of blastocyst implantation in mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    J Assist Reprod Genet 29:163-73. 2012
    ..The purpose of the present study was to investigate the impact of lipopolysaccharide (LPS) on follicle-stimulating hormone (FSH), luteinizing hormone (LH) and their receptors during preimplantation days of pregnancy...
  4. doi request reprint Lipopolysaccharide drives alternation of heat shock proteins and induces failure of blastocyst implantation in mouse
    Mukesh Kumar Jaiswal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Biol Reprod 88:162. 2013
    ..This may ultimately lead to implantation failure in mouse. ..
  5. doi request reprint Lipopolysaccharide-induced modulation in the expression of progesterone receptor and estradiol receptor leads to early pregnancy loss in mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior 474 011, India
    Zygote 21:337-44. 2013
    ..These results suggest that PR and ER play an important role in Gram-negative bacteria infection and induced implantation failure in mouse...
  6. doi request reprint Bacterial endotoxin (LPS)-induced DNA damage in preimplanting embryonic and uterine cells inhibits implantation
    Yogesh Kumar Jaiswal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Fertil Steril 91:2095-103. 2009
    ..To investigate lipopolysaccharide (LPS)-induced DNA damage in preimplanting embryonic and uterine cells during preimplantation period of pregnancy that may ultimately inhibit the process of implantation in mouse...
  7. doi request reprint Lipopolysaccharide induces alterations in ovaries and serum level of progesterone and 17β-estradiol in the mouse
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Fertil Steril 95:1471-4. 2011
    ..5 of pregnancy because of lipopolysaccharide treatment, which reflect a gram-negative bacterial infection, may be responsible for ovarian dysfunction and altered P(4) and E(2) level in serum...
  8. pmc Altered autophagic flux enhances inflammatory responses during inflammation-induced preterm labor
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, IL
    Sci Rep 5:9410. 2015
    ..These novel findings represent the first evidence of an association between altered autophagic flux and hyper-inflammation and labor in IPTL. ..
  9. pmc Intrauterine infection and preterm labor
    Varkha Agrawal
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, 2650 Ridge Avenue, Evanston, IL 60201, USA
    Semin Fetal Neonatal Med 17:12-9. 2012
    ....
  10. pmc Depletion of polymorphonuclear leukocytes has no effect on preterm delivery in a mouse model of Escherichia coli-induced labor
    Yana Filipovich
    Department of Obstetrics and Gynecology, NorthShore University Healthsystem, Evanston, IL
    Am J Obstet Gynecol 213:697.e1-10. 2015
    ..The objective of the study was to investigate the role of polymorphonuclear leukocytes (PMNs) in a mouse model of Escherichia coli-induced labor...
  11. doi request reprint Lipopolysaccharide alters the vaginal electrical resistance in cycling and pregnant mice
    Varkha Agrawal
    Molecular Biology and Reproductive Immunology Laboratory, School of Studies in Biochemistry, Jiwaji University, Gwalior, India
    Am J Reprod Immunol 61:158-66. 2009
    ..The objective of present investigation is to measure the vaginal electrical resistance (VER) in LPS-treated normal cycling and pregnant female mice...