Hasan Acar

Summary

Publications

  1. ncbi request reprint Micronucleus incidence and their chromosomal origin related to therapy in acute lymphoblastic leukemia (ALL) patients: detection by micronucleus and FISH techniques
    H Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya, Turkey
    Teratog Carcinog Mutagen 21:341-7. 2001
  2. ncbi request reprint Relation of glutathione S-transferase genotypes (GSTM1 and GSTT1) to laryngeal squamous cell carcinoma risk
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Meram Medical Faculty, Vali Izzet Pasa Caddesi, Konya 42090, Turkey
    Cancer Genet Cytogenet 169:89-93. 2006
  3. ncbi request reprint Evaluation of chromosome 8 and 11 aneuploidies in washings and biopsy materials of bladder transitional cell carcinoma
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya 42080, Turkey
    Cancer Genet Cytogenet 142:25-9. 2003
  4. ncbi request reprint Determination of allelic deletion of multiple endocrine neoplasm type 1 (MEN1) gene in acute myeloid leukemia (AML) by application of FISH-TSA technique
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya, Turkey
    Teratog Carcinog Mutagen 22:369-75. 2002
  5. ncbi request reprint Evaluation of segregation patterns of 21;21 Robertsonian translocation along with sex chromosomes and interchromosomal effects in sperm nuclei of carrier by FISH technique
    Hasan Acar
    Department of Medical Biology and Genetics, Faculty of Medicine, Selcuk University, Konya, Turkey
    Mol Reprod Dev 63:232-6. 2002
  6. ncbi request reprint Reliability and efficiency of interphase-fish with alpha-satellite probe for detection of aneuploidy
    H Acar
    Department of Medical Genetics and Biology, Selcuk University, Medical Faculty, Konya, Turkey
    Genet Couns 13:11-7. 2002
  7. ncbi request reprint Analysis of chromosomes 9 and 11 aneuploidy frequency in pleural effusion of patients with and without malignancy: interphase FISH technique
    Tulin Cora
    Department of Medical Genetics, Seķuk University, Medical Faculty, Konya, Turkey
    Cancer Biol Ther 4:248-51. 2005
  8. ncbi request reprint Molecular cytogenetic detection of meiotic segregation patterns in sperm nuclei of carriers of 46,XY,t(15;17)(q21; q25)
    Tulin Cora
    Department of Medical Genetics, Medical Faculty, Selcuk University, Konya, Turkey
    J Androl 23:793-8. 2002
  9. pmc PAX9 polymorphisms and susceptibility with sporadic tooth agenesis in Turkish populations: a case-control study
    Eren Isman
    Department of Orthodontics, Faculty of Dentistry, Gaziantep University, Gaziantep 27310, Turkey
    BMC Genomics 14:733. 2013
  10. doi request reprint Evaluation of HLA-A, -B, -Cw, and -DRB1 alleles frequency in Turkish patients with nasal polyposis
    Bahar Keles
    Department of Otolaryngology Head and Neck Surgery, Selcuk University, Meram, Konya, Turkey
    Otolaryngol Head Neck Surg 139:580-5. 2008

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Micronucleus incidence and their chromosomal origin related to therapy in acute lymphoblastic leukemia (ALL) patients: detection by micronucleus and FISH techniques
    H Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya, Turkey
    Teratog Carcinog Mutagen 21:341-7. 2001
    ..We concluded that antileukemic agents induced the somatic genetic damage but this damage is not related to any specific chromosome studied...
  2. ncbi request reprint Relation of glutathione S-transferase genotypes (GSTM1 and GSTT1) to laryngeal squamous cell carcinoma risk
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Meram Medical Faculty, Vali Izzet Pasa Caddesi, Konya 42090, Turkey
    Cancer Genet Cytogenet 169:89-93. 2006
    ..Investigation and determination of the genetic basis of LSCC may contribute to detection of risk groups and to prevent LSCC in the population...
  3. ncbi request reprint Evaluation of chromosome 8 and 11 aneuploidies in washings and biopsy materials of bladder transitional cell carcinoma
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya 42080, Turkey
    Cancer Genet Cytogenet 142:25-9. 2003
    ..It might predict genetic progression of these tumors, which might be related to tumor stage, because higher stages of tumors showed a higher incidence of aneuploidies of chromosomes 8 and 11...
  4. ncbi request reprint Determination of allelic deletion of multiple endocrine neoplasm type 1 (MEN1) gene in acute myeloid leukemia (AML) by application of FISH-TSA technique
    Hasan Acar
    Department of Medical Genetics, Selcuk University, Medical Faculty, Konya, Turkey
    Teratog Carcinog Mutagen 22:369-75. 2002
    ..0%). Our study indicates that allelic deletion of the MEN1 gene is not a major cause or a primary event in tumorigenesis of AML, although the long arm (q13 region) of chromosome 11 involves a chromosomal rearrangement in AML...
  5. ncbi request reprint Evaluation of segregation patterns of 21;21 Robertsonian translocation along with sex chromosomes and interchromosomal effects in sperm nuclei of carrier by FISH technique
    Hasan Acar
    Department of Medical Biology and Genetics, Faculty of Medicine, Selcuk University, Konya, Turkey
    Mol Reprod Dev 63:232-6. 2002
    ..Three color-FISH analysis, using different probe combinations, seems a rapid and accurate tool for direct analysis of meiotic segregation product...
  6. ncbi request reprint Reliability and efficiency of interphase-fish with alpha-satellite probe for detection of aneuploidy
    H Acar
    Department of Medical Genetics and Biology, Selcuk University, Medical Faculty, Konya, Turkey
    Genet Couns 13:11-7. 2002
    ..These centromeric sequence changes may have pathological significance in the appearance of aneuploidy because they may be involved in the important centromere function...
  7. ncbi request reprint Analysis of chromosomes 9 and 11 aneuploidy frequency in pleural effusion of patients with and without malignancy: interphase FISH technique
    Tulin Cora
    Department of Medical Genetics, Seķuk University, Medical Faculty, Konya, Turkey
    Cancer Biol Ther 4:248-51. 2005
    ..The present study indicates that there is a association between chromosomes aneuploidies and pleural effusion cell status. Chromosome aneuploidies in non-malignant group may be an indicator of premalignancy...
  8. ncbi request reprint Molecular cytogenetic detection of meiotic segregation patterns in sperm nuclei of carriers of 46,XY,t(15;17)(q21; q25)
    Tulin Cora
    Department of Medical Genetics, Medical Faculty, Selcuk University, Konya, Turkey
    J Androl 23:793-8. 2002
    ....
  9. pmc PAX9 polymorphisms and susceptibility with sporadic tooth agenesis in Turkish populations: a case-control study
    Eren Isman
    Department of Orthodontics, Faculty of Dentistry, Gaziantep University, Gaziantep 27310, Turkey
    BMC Genomics 14:733. 2013
    ..Blood samples were collected from each individual and DNA was extracted. To determine the polymorphisms, PCR-RFLP method was used...
  10. doi request reprint Evaluation of HLA-A, -B, -Cw, and -DRB1 alleles frequency in Turkish patients with nasal polyposis
    Bahar Keles
    Department of Otolaryngology Head and Neck Surgery, Selcuk University, Meram, Konya, Turkey
    Otolaryngol Head Neck Surg 139:580-5. 2008
    ..To evaluate whether there is a relationship between HLA-A, -B, -Cw, and -DRB1 alleles and developing nasal polyposis (NP)...
  11. doi request reprint Glutathione S-transferase M1 and T1 genotypes and myocardial infarction
    Tulin Cora
    Department of Medical Genetics, Medical Faculty of Selçuk University, Konya, Turkey
    Mol Biol Rep 40:3263-7. 2013
    ..In addition, there was additional effects of smoking when smoking and non-smoking groups were compared...
  12. ncbi request reprint Lack of association between the glutathione-s-transferase genes (GSTT1 and GSTM1) and nasal polyposis
    Hamdi Arbag
    Department of Otolaryngology Head and Neck Surgery, University of Selcuk, Meram Medical School, Konya, Turkey
    Rhinology 44:14-8. 2006
    ..To evaluate the glutation-S-transferase (GST) polymorphisms (GSTM1 and GSTT1) in nasal polyposis (NP)...
  13. ncbi request reprint Micronucleus frequency in acquired middle ear cholesteatoma
    Kayhan Ozturk
    Department of Otolaryngology, Meram Medical Faculty, Selcuk University, Konya, Turkey
    Acta Otolaryngol 124:924-8. 2004
    ..To determine the micronucleus (MN) frequency of acquired cholesteatoma tissue using an MN assay...
  14. ncbi request reprint Meiotic segregation analysis of reciprocal translocations both in sperms and blastomeres
    Tahsin Yakut
    Medical Genetics Department, Faculty of Medicine, Uludag University, Bursa, Turkey
    Am J Med Genet A 140:1074-82. 2006
    ..001). In conclusion, FISH analysis of sperm and blastomere for reciprocal translocation carriers effectively estimates the approximate risk of unbalanced products and this result might ensure valuable genetic counseling...
  15. ncbi request reprint HLA-B27 subtypes in Turkish patients with ankylosing spondylitis and healthy controls
    Muradiye Acar
    Department of Genetics, Selcuk University Medical School, Konya, Turkey
    Rheumatol Int 32:3103-5. 2012
    ..Our results show that the frequency of HLA-B27 subtypes is not significantly different between patients and controls (P > 0.10)...
  16. ncbi request reprint Frequency of recombinant and nonrecombinant products of pericentric inversion of chromosome 1 in sperm nuclei of carrier: by FISH technique
    Tahsin Yakut
    Department of Medical Biology and Genetics, Uludag University, Faculty of Medicine, Bursa, Turkey
    Mol Reprod Dev 66:67-71. 2003
    ..The use of FISH, using different probe combination, in sperm nuclei has proved to be an accurate approach to determine the meiotic segregation patterns and could help to better establish a reproductive prognosis and genetic counseling...
  17. ncbi request reprint Evaluation of c-MYC status in primary acquired cholesteatoma by using fluorescence in situ hybridization technique
    Kayhan Ozturk
    Department of Otolaryngology, Meram Medical Faculty, Selcuk University, Konya, Turkey
    Otol Neurotol 27:588-91. 2006
    ..The object of study was to investigate the status of c-MYC oncogene in primary acquired cholesteatoma...
  18. ncbi request reprint Evaluation of aneuploidy frequency for chromosomes 6 and 17 in eyelid tumours using the FISH technique
    Ahmet Ozkagnici
    Department of Ophthalmology, Selcuk University, Meram Medical Faculty, Konya 42080, Turkey
    Cell Biol Int 31:215-9. 2007
    ..These findings indicate that acquisition of chromosome aneuploidies in eyelid tumours may have an important pathogenic role in both BCC and SCC of the eyelid area...
  19. ncbi request reprint Analysis of chromosomes 8 and 17 aneuploidies in laryngeal squamous cell carcinoma by fluorescence in situ hybridization
    Kayhan Ozturk
    Departments of Otolaryngology, Meram Medical Faculty, Selcuk University, Konya, Turkey
    Laryngoscope 114:1005-10. 2004
    ....
  20. doi request reprint Platelet glycoprotein Ibalpha gene polymorphism and massive or submassive pulmonary embolism
    Ahmet Soylu
    Department of Cardiology, Meram Medical School of Selcuk University, S U Meram Tip Fakültesi Kardiyoloji AD, Konya, Turkey
    J Thromb Thrombolysis 27:259-66. 2009
    ..This study was designed to investigate the effect of platelet glycoprotein Ibalpha Kozak polymorphism on the clinical presentation of the patients with acute pulmonary embolism...
  21. ncbi request reprint Evaluation of relationship between chromosome 22 and p53 gene alterations and the subtype of meningiomas by the interphase-FISH technique
    Tahsin Yakut
    Department of Medical Biology and Genetics, Faculty of Medicine, University of Uludag, Bursa, Turkey
    Teratog Carcinog Mutagen 22:217-25. 2002
    ....
  22. doi request reprint Repeated in vitro fertilization failure and its relation with thrombophilia
    Aynur Simur
    Department of Obstetrics and Gynecology, Meram Medical Faculty, Selcuk University, Konya, Turkey
    Gynecol Obstet Invest 67:109-12. 2009
    ....
  23. ncbi request reprint Chromosome 8 aneuploidy in acquired cholesteatoma
    Mahmut Selman Yildirim
    Department of Genetics, Faculty of Medicine, Selcuk University, Konya, Turkey
    Acta Otolaryngol 123:372-6. 2003
    ..To investigate the incidence of chromosome 8 aneuploidy in acquired cholesteatoma...
  24. doi request reprint Lack of association between leptin levels and leptin gene polymorphism in obese women
    Nilsel Okudan
    Department of Physiology, Faculty of Medicine, Selcuk University, Konya, Turkey
    Arch Physiol Biochem 120:136-9. 2014
    ..This data implies that the difference of leptin levels between control and obese groups are more likely to be associated with alterations in the leptin gene other than 25th codon or alterations in the leptin receptor gene...
  25. ncbi request reprint Frequency of chromosome 17 aneuploidy in primary and recurrent pterygium by interphase-fluorescence in situ hybridization
    Umit Kamis
    Department of Ophthalmology, Faculty of Medicine, Selcuk University, Konya, Turkey
    Ophthalmic Res 38:89-94. 2006
    ..To investigate chromosome 17 numerical aberrations by using fluorescence in situ hybridization (FISH) in pterygia and to find out whether there is any association between chromosome 17 aneuploidy and recurrent pterygia...
  26. ncbi request reprint Evaluation of leptin level and Ob gene polymorphism in patients with Behcet's disease
    Nilsel Okudan
    Department of Physiology, Meram Faculty of Medicine, Selcuk University, 42080 Konya, Turkey
    Arch Dermatol Res 298:127-30. 2006
    ..Neither Behcet's disease nor serum leptin level was found to be related to codon 25 polymorphism. We concluded that leptin 25CAG polymorphism is not associated with Behcet's disease and serum leptin level...
  27. ncbi request reprint 46,XX maleness and 46,XX 21-hydroxylase deficiency in dizygotic twins: association or coincidence?
    Mehmet Emre Atabek
    Department of Pediatric Endocrinology and Diabetes, Faculty of Medicine, Selcuk University, Konya, Turkey
    J Pediatr Endocrinol Metab 20:743-5. 2007
    ..Association of congenital adrenal hyperplasia (46,XX 21-hydroxylase deficiency) and 46,XX maleness in twins has not been previously reported...