Summary: Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.

Top Publications

  1. Kemp A, Jones S, Lawson Z, Maguire S. Patterns of burns and scalds in children. Arch Dis Child. 2014;99:316-21 pubmed publisher
    To describe the characteristics of childhood burns and scalds, mechanisms and agents to inform prevention.
  2. Brewster C, Coyle B, Varma S. Trends in hospital admissions for burns in England, 1991-2010: a descriptive population-based study. Burns. 2013;39:1526-34 pubmed publisher
    To describe trends in admissions to English hospitals and 30-day in-hospital mortality associated with a primary diagnosis of burns.
  3. Huan J, TANG J. [Drug-resistance Acinetobacter baumannii infection in burn patients: current situation and countermeasure]. Zhonghua Shao Shang Za Zhi. 2011;27:84-7 pubmed
    ..Measures to effectively control nosocomial infection are warranted. Meanwhile, development of novel therapeutic agents or combination of antibiotics should be considered...
  4. Huang L, Yao Y, Dong N, Yu Y, He L, Sheng Z. Association of high mobility group box-1 protein levels with sepsis and outcome of severely burned patients. Cytokine. 2011;53:29-34 pubmed publisher
    ..The study was performed to observe the systemic release and kinetics of high mobility group box-1 protein (HMGB1) in burned patients...
  5. Renno A, Iwama A, Shima P, Fernandes K, Carvalho J, de Oliveira P, et al. Effect of low-level laser therapy (660 nm) on the healing of second-degree skin burns in rats. J Cosmet Laser Ther. 2011;13:237-42 pubmed publisher
    ..Taken together, our results demonstrate that laser therapy is able to promote skin repair of burned rats as a result of decreasing necrotic area and an up-regulation of COX-2 and VEGF immunoexpression...
  6. Eljaiek R, Dubois M. Hypoalbuminemia in the first 24h of admission is associated with organ dysfunction in burned patients. Burns. 2013;39:113-8 pubmed publisher
    ..We assessed whether hypoalbuminemia in the first 24h of admission is associated with organ dysfunction in patients with severe burns.
  7. Sadeghi Bazargani H, Arshi S, Mashoufi M, Deljavan anvari R, Meshkini M, Mohammadi R. Household related predictors of burn injuries in an Iranian population: a case-control study. BMC Public Health. 2012;12:340 pubmed publisher
    ..Ardabil Province is the coldest province of Iran with high burden of burn injuries. The aim of this study was to determine the household related predictors of unintentional burns in Ardabil Province located at North-West of Iran.
  8. Allorto N, Clarke D, Thomson S. A cost model case comparison of current versus modern management of burns at a regional hospital in South Africa. Burns. 2011;37:1033-7 pubmed publisher
    ..We developed a costing model for both approaches to analyse financial costs in a developing country burns unit.
  9. De Young A, Kenardy J, Cobham V, Kimble R. Prevalence, comorbidity and course of trauma reactions in young burn-injured children. J Child Psychol Psychiatry. 2012;53:56-63 pubmed publisher
    ..However, to date this population has been largely neglected. This study examined the prevalence, onset, comorbidity and recovery patterns of posttrauma reactions in young children with burns.

More Information


  1. Forster N, Zingg M, Haile S, Künzi W, Giovanoli P, Guggenheim M. 30 years later--does the ABSI need revision?. Burns. 2011;37:958-63 pubmed publisher
    ..patient demographics together with constant developments in burn care, the predictive accuracy of the Abbreviated Burns Severity Index (ABSI) - first described in 1982 - for estimating the mortality of present day burns patients, may ..
  2. Izamis M, Sharma N, Uygun B, Bieganski R, Saeidi N, Nahmias Y, et al. In situ metabolic flux analysis to quantify the liver metabolic response to experimental burn injury. Biotechnol Bioeng. 2011;108:839-52 pubmed publisher
    Trauma such as burns induces a hypermetabolic response associated with altered central carbon and nitrogen metabolism...
  3. Miller K, Rodger S, Kipping B, Kimble R. A novel technology approach to pain management in children with burns: A prospective randomized controlled trial. Burns. 2011;37:395-405 pubmed publisher
  4. Mitra B, Wasiak J, Cameron P, O Reilly G, Dobson H, Cleland H. Early coagulopathy of major burns. Injury. 2013;44:40-3 pubmed publisher
    The pathophysiology and time-course of coagulopathy post major burns are inadequately understood...
  5. Sadeghi Bazargani H, Arshi S, Ekman R, Mohammadi R. Prevention-oriented epidemiology of burns in Ardabil provincial burn centre, Iran. Burns. 2011;37:521-7 pubmed publisher
    In preventing burns, it is essential to know how they occur and which population groups, environments and heating appliances can be targeted for prevention work...
  6. Hurler J, Berg O, Skar M, Conradi A, Johnsen P, Skalko Basnet N. Improved burns therapy: liposomes-in-hydrogel delivery system for mupirocin. J Pharm Sci. 2012;101:3906-15 pubmed publisher
    Wounds, particularly burns, are prone to colonization of potentially life-threatening bacteria. Local delivery of antimicrobial agents in sufficient quantities and over longer period of time can reduce risk of burn infections...
  7. Ebid A, Ahmed M, Mahmoud Eid M, Mohamed M. Effect of whole body vibration on leg muscle strength after healed burns: a randomized controlled trial. Burns. 2012;38:1019-26 pubmed publisher
    To investigate the effects of eight weeks whole body vibration training program on leg muscle strength (force-producing capacity) in adults after healed burns.
  8. Mann E, Baun M, Meininger J, Wade C. Comparison of mortality associated with sepsis in the burn, trauma, and general intensive care unit patient: a systematic review of the literature. Shock. 2012;37:4-16 pubmed publisher
    ..were used: "sepsis," septicemia," "septic shock," "epidemiology," "burns," "thermal injury," "trauma," "wounds and injuries," "critical care," ..
  9. Al Waili N, Salom K, Al Ghamdi A. Honey for wound healing, ulcers, and burns; data supporting its use in clinical practice. ScientificWorldJournal. 2011;11:766-87 pubmed publisher
    The widespread existence of unhealed wounds, ulcers, and burns has a great impact on public health and economy...
  10. Van Loey N, van Beeck E, Faber B, van de Schoot R, Bremer M. Health-related quality of life after burns: a prospective multicenter cohort study with 18 months follow-up. J Trauma Acute Care Surg. 2012;72:513-20 pubmed
    ..The aim of this study was to quantify health loss in patients with burns and to assess the contribution of injury extent, age, gender, and psychologic factors to HRQOL and speed of ..
  11. Singer A, Hirth D, McClain S, Clark R. Lack of agreement between gross visual and histological assessment of burn reepithelialization in a porcine burn model. J Burn Care Res. 2012;33:286-90 pubmed publisher
    ..Forty-eight 2.5- × 2.5-cm burns were created on the flanks of pig's using an aluminum bar (150 g) preheated to 80°C for 20 seconds...
  12. Butler K, Goverman J, Ma H, Fischman A, Yu Y, Bilodeau M, et al. Stem cells and burns: review and therapeutic implications. J Burn Care Res. 2010;31:874-81 pubmed publisher
    ..Through a review of the literature, this article seeks to illustrate applications of stem cell therapy to burn care and to highlight promising areas of research...
  13. Zahs A, Bird M, Ramirez L, Turner J, Choudhry M, Kovacs E. Inhibition of long myosin light-chain kinase activation alleviates intestinal damage after binge ethanol exposure and burn injury. Am J Physiol Gastrointest Liver Physiol. 2012;303:G705-12 pubmed publisher
    ..These data suggest that MLCK activity may promote morphological and inflammatory responses in the ileum following ethanol exposure and burn injury. ..
  14. Sio S, Ang S, Lu J, Moochhala S, Bhatia M. Substance P upregulates cyclooxygenase-2 and prostaglandin E metabolite by activating ERK1/2 and NF-kappaB in a mouse model of burn-induced remote acute lung injury. J Immunol. 2010;185:6265-76 pubmed publisher
    ..To our knowledge, we show for the first time that SP-NK1R signaling markedly elevates COX-2 activity via ERK1/2 and NF-?B, leading to remote ALI after burn...
  15. Duteille F, Perrot P. Management of 2nd-degree facial burns using the Versajet(®) hydrosurgery system and xenograft: a prospective evaluation of 20 cases. Burns. 2012;38:724-9 pubmed publisher
    There is no single therapeutic scheme for the management of intermediary 2nd-degree facial burns, which can cause problems because of their uncertain course...
  16. Rastegar Lari A, Azimi L, Rahbar M, Fallah F, Alaghehbandan R. Phenotypic detection of Klebsiella pneumoniae carbapenemase among burns patients: first report from Iran. Burns. 2013;39:174-6 pubmed publisher
    ..This study is the first report of its kind investigating the resistance to carbapenems among burns patients in Iran.
  17. van Baar M, Polinder S, Essink Bot M, Van Loey N, Oen I, Dokter J, et al. Quality of life after burns in childhood (5-15 years): children experience substantial problems. Burns. 2011;37:930-8 pubmed publisher
    The aim of our study was to assess prevalence and correlates related to sub optimal outcome after pediatric burns and to make a comparison with pediatric injuries not related to burns...
  18. Dai T, Tanaka M, Huang Y, Hamblin M. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects. Expert Rev Anti Infect Ther. 2011;9:857-79 pubmed publisher
    ..Studies covering applications of chitosan in wounds and burns can be classified into in vitro, animal and clinical studies...
  19. Bloemen M, van der Wal M, Verhaegen P, Nieuwenhuis M, van Baar M, van Zuijlen P, et al. Clinical effectiveness of dermal substitution in burns by topical negative pressure: a multicenter randomized controlled trial. Wound Repair Regen. 2012;20:797-805 pubmed publisher
    ..study was to investigate if application of a dermal substitute in combination with TNP improves scar quality after burns. In a four-armed multicenter randomized controlled trial, a split-skin graft with or without a dermal substitute ..
  20. Moiemen N, Shale E, Drysdale K, Smith G, Wilson Y, Papini R. Acticoat dressings and major burns: systemic silver absorption. Burns. 2011;37:27-35 pubmed publisher
    ..An earlier study of Acticoat use in small burns showed transient elevations of serum silver...
  21. Al Shaqsi S, Al Kashmiri A, Al Bulushi T. Epidemiology of burns undergoing hospitalization to the National Burns Unit in the Sultanate of Oman: a 25-year review. Burns. 2013;39:1606-11 pubmed publisher
    The aim of this study was to describe the epidemiology of burns admitted to the National Burns Unit (NBU) in the Sultanate of Oman between 1987 and 2011.
  22. Costantini T, Krzyzaniak M, Cheadle G, Putnam J, Hageny A, Lopez N, et al. Targeting ?-7 nicotinic acetylcholine receptor in the enteric nervous system: a cholinergic agonist prevents gut barrier failure after severe burn injury. Am J Pathol. 2012;181:478-86 pubmed publisher
  23. Kurihara T, Jones C, Yu Y, Fischman A, Watada S, Tompkins R, et al. Resolvin D2 restores neutrophil directionality and improves survival after burns. FASEB J. 2013;27:2270-81 pubmed publisher
    Following severe burns and trauma injuries, the changes of neutrophil migratory phenotype are a double-edged sword...
  24. Peck M. Epidemiology of burns throughout the World. Part II: intentional burns in adults. Burns. 2012;38:630-7 pubmed publisher
    A significant number of burns and deaths from fire are intentionally wrought...
  25. Krzyzaniak M, Cheadle G, Peterson C, Loomis W, Putnam J, Wolf P, et al. Burn-induced acute lung injury requires a functional Toll-like receptor 4. Shock. 2011;36:24-9 pubmed publisher
    ..Toll-like receptor 4 KO animals were clearly protected and had a much less severe lung injury. Our data suggest that burn-induced ALI is a TLR4-dependent process...
  26. Bakker A, Maertens K, Van Son M, Van Loey N. Psychological consequences of pediatric burns from a child and family perspective: a review of the empirical literature. Clin Psychol Rev. 2013;33:361-71 pubmed publisher
    ..practice, we reviewed the empirical literature on emotional, behavioral and social outcomes in children with burns and their families published between 1989 and 2011. A systematic search of the literature yielded 75 articles...
  27. Sen S, Greenhalgh D, Palmieri T. Review of burn research for the year 2010. J Burn Care Res. 2012;33:577-86 pubmed publisher
    ..We have found that burn research continues to be prolific throughout the world and reflects the wide-ranging and complex care requirements of burn survivors...
  28. Bohr S, Patel S, Shen K, Vitalo A, Brines M, Cerami A, et al. Alternative erythropoietin-mediated signaling prevents secondary microvascular thrombosis and inflammation within cutaneous burns. Proc Natl Acad Sci U S A. 2013;110:3513-8 pubmed publisher
    ..bind the erythropoietic EPO receptor homodimer, on the progression of secondary tissue damage following cutaneous burns. For this purpose, a deep partial thickness cutaneous burn injury was applied on the back of mice, followed by ..
  29. Cirodde A, Leclerc T, Jault P, Duhamel P, Lataillade J, Bargues L. Cultured epithelial autografts in massive burns: a single-center retrospective study with 63 patients. Burns. 2011;37:964-72 pubmed publisher
    Cultured epithelial autografts (CEAs) have long been used to tackle limited donor site availability and difficulty of permanent skin coverage in massive burns, but this approach still has limited documentation.
  30. Mohammadi A, Johari H, Eskandari S. Effect of amniotic membrane on graft take in extremity burns. Burns. 2013;39:1137-41 pubmed publisher
    Several studies have shown that the application of amniotic membrane as a biological dressing in the management of burns is accompanied by rapid re-epithelialisation and healing as it diminishes the oozing of plasma, bacterial count and ..
  31. Mosier M, Pham T, Klein M, Gibran N, Arnoldo B, Gamelli R, et al. Early enteral nutrition in burns: compliance with guidelines and associated outcomes in a multicenter study. J Burn Care Res. 2011;32:104-9 pubmed publisher
    ..advocate that initiation of EN by 24 hours be used as a formal recommendation in nutrition guidelines for severe burns, and that nutrition guidelines be actively disseminated to individual burn centers to permit a change in practice.
  32. Mahar P, Padiglione A, Cleland H, Paul E, Hinrichs M, Wasiak J. Pseudomonas aeruginosa bacteraemia in burns patients: Risk factors and outcomes. Burns. 2010;36:1228-33 pubmed publisher
    We aimed to identify the risk factors for, and outcomes of Pseudomonas aeruginosa bacteraemia in adult burns patients.
  33. Wolf S, Sterling J, Hunt J, Arnoldo B. The year in burns 2010. Burns. 2011;37:1275-87 pubmed publisher
    ..article reviews those with the most impact on burn treatment according to the Editor of one of the major journals (Burns) and his colleagues...
  34. Johnson L, Shupp J, Pavlovich A, Pezzullo J, Jeng J, Jordan M. Hospital length of stay--does 1% TBSA really equal 1 day?. J Burn Care Res. 2011;32:13-9 pubmed publisher
    ..Age alone is not a significant predictor of increasing LOS. The cause of burns was predominantly flame related across all deciles of TBSA, and most etiologies for burn demonstrate the predicted ..
  35. Palma S, Metnitz P, Kamolz L, Frey M, Druml W. [Acute renale failure in burns - causes, consequences and avoidance strategies]. Anasthesiol Intensivmed Notfallmed Schmerzther. 2011;46:12-9 pubmed publisher
    ..Especially critical ill patients, who are suffering from major burns, have a high risk to develop ARF as a consequence of their trauma...
  36. Tang Y, Chapman T, Brooks P. Use of tranexamic acid to reduce bleeding in burns surgery. J Plast Reconstr Aesthet Surg. 2012;65:684-6 pubmed publisher
    ..first time, the use of topical tranexamic acid as an adjunct to traditional methods in the control of bleeding in burns surgery...
  37. Kahn S, Beers R, Lentz C. Resuscitation after severe burn injury using high-dose ascorbic acid: a retrospective review. J Burn Care Res. 2011;32:110-7 pubmed publisher
    ..The effects of VC should be further studied in a large-scale, prospective, randomized trial...
  38. Jeschke M, Kraft R, Song J, Gauglitz G, Cox R, Brooks N, et al. Insulin protects against hepatic damage postburn. Mol Med. 2011;17:516-22 pubmed publisher
    ..These results support the use of insulin therapy after traumatic injury to improve patient outcomes. ..
  39. Breederveld R, Nieuwenhuis M, Tuinebreijer W, Aardenburg B. Effect of training in the Emergency Management of Severe Burns on the knowledge and performance of emergency care workers as measured by an online simulated burn incident. Burns. 2011;37:281-7 pubmed publisher
    To determine the value of training for the Emergency Management of Severe Burns (EMSB) for medical and nursing staff working in emergency care as measured by their performance in a simulated burn incident online program.
  40. Porter C, Cotter M, Diaz E, Jennings K, Herndon D, Børsheim E. Amino acid infusion fails to stimulate skeletal muscle protein synthesis up to 1 year after injury in children with severe burns. J Trauma Acute Care Surg. 2013;74:1480-5 pubmed publisher
    ..Subsequently, the purpose of this study was to determine skeletal muscle FSR in response to AA infusion in severely burned pediatric patients at discharge from hospital and at 6 and 12 months after injury...
  41. Nidadavolu P, Amor W, Tran P, Dertien J, Colmer Hamood J, Hamood A. Garlic ointment inhibits biofilm formation by bacterial pathogens from burn wounds. J Med Microbiol. 2012;61:662-71 pubmed publisher
    ..Thus, GarO could be used as a prophylactic therapy to prevent wound biofilms caused by both Gram-negative and Gram-positive bacteria from forming, and may be a potential therapy for disrupting established staphylococcal biofilms...
  42. Fang Y, Xu P, Gu C, Wang Y, Fu X, Yu W, et al. Ulinastatin improves pulmonary function in severe burn-induced acute lung injury by attenuating inflammatory response. J Trauma. 2011;71:1297-304 pubmed publisher
    ..Ulinastatin is potentially an effective intervention, because it attenuates the systemic inflammatory response induced by endotoxin and improves myocardial function during ischemic shock and reperfusion...
  43. Singer A, Taira B, Lin F, Lim T, Anderson R, McClain S, et al. Curcumin reduces injury progression in a rat comb burn model. J Burn Care Res. 2011;32:135-42 pubmed publisher
    ..Two comb burns were created on the dorsum of Sprague-Dawley rats (weight, 300 g) using a brass comb with four rectangular prongs ..
  44. Kimball Z, Patil S, Mansour H, Marano M, Petrone S, Chamberlain R. Clinical outcomes of isolated lower extremity or foot burns in diabetic versus non-diabetic patients: a 10-year retrospective analysis. Burns. 2013;39:279-84 pubmed publisher
    ..As a result, DM patients will constitute a large proportion of Burn Center admissions, with burns typically due to contact burn or scalding...
  45. Salinas J, Chung K, Mann E, Cancio L, Kramer G, Serio Melvin M, et al. Computerized decision support system improves fluid resuscitation following severe burns: an original study. Crit Care Med. 2011;39:2031-8 pubmed publisher
    ..The goal of this study was to analyze the efficacy of a computerized open-loop decision support system for burn resuscitation compared to historical controls...
  46. Ter Smitten M, de Graaf R, Van Loey N. Prevalence and co-morbidity of psychiatric disorders 1-4 years after burn. Burns. 2011;37:753-61 pubmed publisher
    ..We examined the prevalence of DSM-IV Axis I disorders in burn patients 1-4 years after burn, using a standardized structured clinical interview and comparing findings with a representative general population sample...
  47. Bowman S, Aitken M, Maham S, Sharar S. Trends in hospitalisations associated with paediatric burns. Inj Prev. 2011;17:166-70 pubmed publisher
    In the United States, burns are the third leading cause of unintentional injury death in children aged 1-14 years, accounting for more than 600 deaths per year in children aged 0-19 years.
  48. Leclerc T, Thepenier C, Jault P, Bey E, Peltzer J, Trouillas M, et al. Cell therapy of burns. Cell Prolif. 2011;44 Suppl 1:48-54 pubmed publisher
    Severe burns remain a life-threatening local and general inflammatory condition often with serious sequelae, despite remarkable progress in their treatment over the past three decades...
  49. Ahuja R, Dash J, Shrivastava P. A comparative analysis of liquefied petroleum gas (LPG) and kerosene related burns. Burns. 2011;37:1403-10 pubmed publisher
    Previous studies from our department reflected a trend of decreasing incidence of burns culminating from rising income levels, which were bringing about a change in the cooking fuel in many urban households [1,2]...
  50. Tavares Pereira D, Lima Ribeiro M, de Pontes Filho N, Carneiro Leão A, Correia M. Development of animal model for studying deep second-degree thermal burns. J Biomed Biotechnol. 2012;2012:460841 pubmed publisher
    ..It is concluded that the model established is applicable in obtaining deep second-degree thermal burns in order to evaluate the healing action of therapeutic agents of topical use.
  51. Zakine G, Barbier V, Garcia Filipe S, Luboinski J, Papy Garcia D, Chachques J, et al. Matrix therapy with RGTA OTR4120 improves healing time and quality in hairless rats with deep second-degree burns. Plast Reconstr Surg. 2011;127:541-50 pubmed publisher
    ..RGTA restores the normal matrix architecture and supports tissue regeneration. In this study, the authors evaluated the effects of RGTA on epidermal repair and dermal remodeling in a rat burn model...
  52. Rahmanian Schwarz A, Beiderwieden A, Willkomm L, Amr A, Schaller H, Lotter O. A clinical evaluation of Biobrane(®) and Suprathel(®) in acute burns and reconstructive surgery. Burns. 2011;37:1343-8 pubmed publisher
    In the treatment of superficial partial-thickness burns, various skin substitutes and temporary dressings offer potential advantages over traditional treatments...
  53. Wu X, Baer L, Wolf S, Wade C, Walters T. The impact of muscle disuse on muscle atrophy in severely burned rats. J Surg Res. 2010;164:e243-51 pubmed publisher
    ..In this study, we sought to determine whether muscle disuse has additional impact on muscle atrophy after severe burn using a rat model combining severe cutaneous burn and hindlimb unloading...