spontaneous fractures


Summary: Fractures occurring as a result of disease of a bone or from some undiscoverable cause, and not due to trauma. (Dorland, 27th ed)

Top Publications

  1. Moayyeri A. Comment on Kanis et al.: the use of clinical risk factors enhances the performance of BMD in the prediction of hip and osteoporotic fractures in men and women. Osteoporos Int. 2008;19:591-2; author reply 593-4 pubmed
  2. Gaitanis I, Hadjipavlou A, Katonis P, Tzermiadianos M, Pasku D, Patwardhan A. Balloon kyphoplasty for the treatment of pathological vertebral compressive fractures. Eur Spine J. 2005;14:250-60 pubmed
  3. Ramisetty N, Pynsent P, Abudu A. Fracture of the femoral neck, the risk of serious underlying pathology. Injury. 2005;36:622-6 pubmed
    ..Four patients (15%) in group III and six patients (75%) in group IV had metastases on histological examination. It is concluded that only groups III and IV are likely to have fractures due to metastatic disease...
  4. Cristofolini L, Juszczyk M, Martelli S, Taddei F, Viceconti M. In vitro replication of spontaneous fractures of the proximal human femur. J Biomech. 2007;40:2837-45 pubmed
    b>Spontaneous fractures (i.e. caused by sudden loading and muscle contraction, not by trauma) represent a significant percentage of proximal femur fractures...
  5. Landa J, Margolis N, Di Cesare P. Orthopaedic management of the patient with osteopetrosis. J Am Acad Orthop Surg. 2007;15:654-62 pubmed
    ..Management with open reduction and internal fixation and with intramedullary fixation of fractures is difficult but possible. Reported results of total hip and total knee arthroplasties are excellent...
  6. Tokuda O, Hayashi N, Taguchi K, Matsunaga N. Dynamic contrast-enhanced perfusion MR imaging of diseased vertebrae: analysis of three parameters and the distribution of the time-intensity curve patterns. Skeletal Radiol. 2005;34:632-8 pubmed
    ..To assess the diagnostic value of perfusion MR imaging of diseased vertebrae by analysis of three parameters and the distribution of the time-intensity curve (TIC) patterns...
  7. Giangregorio L, Papaioannou A, Cranney A, Zytaruk N, Adachi J. Fragility fractures and the osteoporosis care gap: an international phenomenon. Semin Arthritis Rheum. 2006;35:293-305 pubmed
    ..To describe practice patterns in the management of osteoporosis after fragility fracture...
  8. Reventlow S, Bang H. Brittle bones: ageing or threat of disease exploring women's cultural models of osteoporosis. Scand J Public Health. 2006;34:320-6 pubmed
    ..To explore elderly Danish women's ideas about osteoporosis and the possible threat to health. The authors discuss the issue of risk interpretations in itself, using osteoporosis as a case...
  9. de Sanctis N, Andreacchio A. Elastic stable intramedullary nailing is the best treatment of unicameral bone cysts of the long bones in children?: Prospective long-term follow-up study. J Pediatr Orthop. 2006;26:520-5 pubmed
    ..Each lesion responded to treatment after the nailing. This method can solve in time the pathology, and we feel that, with skilled hands, this method is the best one for UBC treatment in the long bones of the children...

More Information

Publications111 found, 100 shown here

  1. Yeh H, Berenson J. Myeloma bone disease and treatment options. Eur J Cancer. 2006;42:1554-63 pubmed
    ..As our understanding of the pathophysiology of myeloma bone disease continues to increase, new target therapies will continue to emerge offering new and more advanced options for the management of myeloma bone disease...
  2. Pflugmacher R, Beth P, Schroeder R, Schaser K, Melcher I. Balloon kyphoplasty for the treatment of pathological fractures in the thoracic and lumbar spine caused by metastasis: one-year follow-up. Acta Radiol. 2007;48:89-95 pubmed
    ..To evaluate the clinical and radiographic outcomes of balloon kyphoplasty in patients with fractures of the thoracic and lumbar spine caused by metastatic disease...
  3. Neogi D, Kumar V, Malhotra R. Femoral allograft in the management of osseous hydatidosis presenting as femoral shaft non-union. Arch Orthop Trauma Surg. 2009;129:1627-32 pubmed publisher
    ..At 26 months patient has no recurrence and bony union is seen at host-allograft interface. We present this technique as an extended indication of allograft used in limb reconstruction...
  4. Ohta H. [Evidence for the selective estrogen receptor modulator raloxifene--its pharmacological characteristics, efficacy and safety profiles]. Nihon Rinsho. 2009;67:960-6 pubmed
    ..Notably, the available evidence for raloxifene suggests that the efficacy of raloxifene in preventing bone fractures has not only to do with bone mineral density but also to do with bone quality. ..
  5. Makki D, Matar H, Jacob N, Lipscombe S, Gudena R. Comparison of the reconstruction trochanteric antigrade nail (TAN) with the proximal femoral nail antirotation (PFNA) in the management of reverse oblique intertrochanteric hip fractures. Injury. 2015;46:2389-93 pubmed publisher
    ..Our study suggests that the use of reconstruction system with two screws such as TAN may be more suitable implant for reverse oblique intertrochanteric hip fractures. ..
  6. Páramo Díaz P, Arroyo Hernández M, Rodríguez Vega V, Aroca Peinado M, León Baltasar J, Caba Doussoux P. Surgical treatment of extra-articular distal-third diaphyseal fractures of the humerus using a modified posterior approach and an extra-articular plate. Rev Esp Cir Ortop Traumatol. 2017;61:404-411 pubmed publisher
  7. Dam T, Ewing S, Ancoli Israel S, Ensrud K, Redline S, Stone K. Association between sleep and physical function in older men: the osteoporotic fractures in men sleep study. J Am Geriatr Soc. 2008;56:1665-73 pubmed publisher
    ..Greater sleep fragmentation and hypoxia are associated with poorer physical function in older men. ..
  8. Chadha M, Singh A, Singh A. Hypophosphataemic osteomalacia in neurofibromatosis. Acta Orthop Belg. 2009;75:847-50 pubmed
    ..Association of neurofibromatosis with oncogenic osteomalacia is unusual. We report a rare case of oncogenic osteomalacia with generalized neurofibromatosis which presented to us as pathological fracture...
  9. Javaheri B, Carriero A, Staines K, Chang Y, Houston D, Oldknow K, et al. Phospho1 deficiency transiently modifies bone architecture yet produces consistent modification in osteocyte differentiation and vascular porosity with ageing. Bone. 2015;81:277-91 pubmed publisher
    ..studies have found that Phospho1 KO mice (Phospho1-R74X) display multiple skeletal abnormalities with spontaneous fractures, bowed long bones, osteomalacia and scoliosis...
  10. Willeumier J, van der Hoeven N, Bollen L, Willems L, Fiocco M, Van der Linden Y, et al. Epidermal growth factor receptor mutations should be considered as a prognostic factor for survival of patients with pathological fractures or painful bone metastases from non-small cell lung cancer. Bone Joint J. 2017;99-B:516-521 pubmed publisher
    ..This study shows that NSCLC should not be regarded as a single entity in such models. Cite this article: Bone Joint J 2017;99-B:516-21. ..
  11. Okazaki R. [New development in bisphosphonate treatment. Characteristics and effectiveness of intermittent bisphophonates]. Clin Calcium. 2009;19:30-6 pubmed publisher
    ..In U. S. A. and other countries, orally, monthly risedoronate and ibandronate, intravenously, quarterly ibandronate and yearly zoledronate have been approved for osteoporosis. Their clinical efficacy will be reviewed. ..
  12. Dzyuba G, Reznik L, Erofeev S, Odarchenko D. [Efficiency of local cement reinforcing antibacterial implants in surgical treatment of long bones chronic osteomyelitis]. Khirurgiia (Mosk). 2016;:31-36 pubmed publisher
  13. Bartl R. [Treatment of osteoporosis according to the "European Guidance 2008". Fracture-oriented--economical--cost-effective]. Internist (Berl). 2008;49:1126-36 pubmed publisher
    ..In this paper several aspects are emphasized: improvements in diagnostic evaluation, assessment of the efficacy of fracture-oriented medications, and cost-effectiveness of the treatment of patients with osteoporosis. ..
  14. Ashford R, Hanna S, Park D, Pollock R, Skinner J, Briggs T, et al. Proximal femoral replacements for metastatic bone disease: financial implications for sarcoma units. Int Orthop. 2010;34:709-13 pubmed publisher
    ..Less than half of this is reimbursed under Payment by Results. Endoprosthetic replacement of the proximal femur is an effective treatment of metastases, but is poorly reimbursed under current funding arrangements. ..
  15. Augat P, Buhren V. [Modern implant design for the osteosynthesis of osteoporotic bone fractures]. Orthopade. 2010;39:397-406 pubmed publisher
    ..However, despite modern implant technology, osteoporotic bone fractures remain a significant challenge for the orthopaedic surgeon and require meticulous planning and implementation of the basic principles. ..
  16. Han K, Dang P, Bian N, Chen X, Yang T, Fan Q, et al. Is Limb Salvage With Microwave-induced Hyperthermia Better Than Amputation for Osteosarcoma of the Distal Tibia?. Clin Orthop Relat Res. 2017;475:1668-1677 pubmed publisher
    ..However, these findings should be replicated in larger studies with longer mean duration of followup, and in studies that compare microwave-induced hyperthermia with conventional limb-sparing approaches. Level III, therapeutic study. ..
  17. Nagao S, Ito K, Nakamura I. Spontaneous bilateral femoral neck fractures associated with a low serum level of vitamin D in a young adult. J Arthroplasty. 2009;24:322.e1-4 pubmed publisher
    ..Although, in our case, the patient underwent bilateral femoral head arthroplasty, early diagnosis could have been helpful to avoid further displacement of the fracture and surgical treatment. ..
  18. Schmid L, Klang A, Katic N, Ansón A, Gumpenberger M, Kneissl S. IMAGING DIAGNOSIS-RADIOGRAPHY AND COMPUTED TOMOGRAPHY OF RADIOULNAR ISCHEMIC NECROSIS IN A JACK RUSSELL TERRIER. Vet Radiol Ultrasound. 2016;: pubmed publisher
    ..It should be differentiated from neoplastic or fungal disease. To the authors´ knowledge, this is the first canine case report describing RUIN. ..
  19. Berglund J, Gafni R, Wodajo F, Cowen E, El Maouche D, Chang R, et al. Tumor-induced osteomalacia in association with PTEN-negative Cowden syndrome. Osteoporos Int. 2018;29:993-997 pubmed publisher
    ..Genetic testing revealed a somatic FN1-FGFR1 translocation in the FGF23-producing tumor causing TIO; however, a germline PTEN mutation was not identified. To our knowledge, this is the first reported case of concurrent TIO and CS. ..
  20. Amiri M, Nabipour I, Larijani B, Beigi S, Assadi M, Amiri Z, et al. The relationship of absolute poverty and bone mineral density in postmenopausal Iranian women. Int J Public Health. 2008;53:290-6 pubmed publisher
    ..50 (CI, 1.38-4.51; p = 0.002); OR = 2.40 (CI, 1.56-3.70; p < 0.0001), respectively]. Postmenopausal women under the absolute poverty lines had lower BMDs at all skeletal sites, independent of established osteoporosis risk factors. ..
  21. Tanck E, van Aken J, van der Linden Y, Schreuder H, Binkowski M, Huizenga H, et al. Pathological fracture prediction in patients with metastatic lesions can be improved with quantitative computed tomography based computer models. Bone. 2009;45:777-83 pubmed publisher
    ..72, whereas this coefficient was considerably higher (tau=0.78) for the FE-model. This study showed that the use of a non-linear FE-model can improve the prediction of bone strength compared to the prediction by clinical experts. ..
  22. Araki N, Chuman H, Matsunobu T, Tanaka K, Katagiri H, Kunisada T, et al. Factors associated with the decision of operative procedure for proximal femoral bone metastasis: Questionnaire survey to institutions participating the Bone and Soft Tissue Tumor Study Group of the Japan Clinical Oncology Group. J Orthop Sci. 2017;22:938-945 pubmed publisher
    ..The evaluation system about the bone destruction of metastases needs to be refined through the following prospective randomized study. ..
  23. Lin J, Santiago Torres J, Everhart J, Zayan N, Mayerson J, Scharschmidt T. When is hemiarthroplasty preferable to intramedullary prophylactic fixation of malignant lesions of the proximal femur?. J Surg Oncol. 2017;116:1132-1140 pubmed publisher
    ..9, CI 7.37, 161; P?<?0.001). There is no difference in survival or likelihood of unassisted ambulation after prophylactic femoral fixation with IM nails versus hemiarthroplasty in patients with metastatic disease of proximal femur. ..
  24. Hierholzer J, Fuchs H, Westphalen K, Baumann C, Slotosch C, Schulz R. Incidence of symptomatic vertebral fractures in patients after percutaneous vertebroplasty. Cardiovasc Intervent Radiol. 2008;31:1178-83 pubmed publisher
  25. Kearns A, Kallmes D. Osteoporosis primer for the vertebroplasty practitioner: expanding the focus beyond needles and cement. AJNR Am J Neuroradiol. 2008;29:1816-22 pubmed publisher
    ..This brief review is intended to familiarize neuroradiologists with these aspects so they can advise patients about optimizing fracture risk reduction. ..
  26. Lee S, Lee J, Jeong J, Yoo D, Kim S. A preliminary study on discrimination of osteoporotic fractured group from nonfractured group using support vector machine. Conf Proc IEEE Eng Med Biol Soc. 2008;2008:474-7 pubmed publisher
  27. Bogoch E, Elliot Gibson V, Escott B, Beaton D. The osteoporosis needs of patients with wrist fracture. J Orthop Trauma. 2008;22:S73-8 pubmed publisher
  28. Niu X, Ding Y. [The surgical treatment and outcome of nonmetastatic osteosarcoma of the extremity with pathologic fractures]. Zhonghua Wai Ke Za Zhi. 2008;46:1730-3 pubmed
    ..The performance of a limb-salvage procedure in carefully selected patients with pathologic fracture does not significantly increase the risk of local recurrence or death. ..
  29. Sarahrudi K, Wolf H, Funovics P, Pajenda G, Hausmann J, Vecsei V. Surgical treatment of pathological fractures of the shaft of the humerus. J Trauma. 2009;66:789-94 pubmed publisher
    ..ORIF are preferable to IM fixations for the treatment of metaphyseal fractures and for those patients with a solitary metastasis in the humerus or those with a better prognosis. ..
  30. El Moatasem E, Abdel Rahman M, Eid M. Extended curettage and adjuvant therapy for benign tumors of the talus. Foot (Edinb). 2015;25:79-83 pubmed publisher
    ..No patient experienced recurrence or complications related to cryotherapy. Intralesional extended curettage with bone grafting and cryotherapy is a successful, safe, and efficient treatment of benign tumors of the talus. ..
  31. Tanaka T, Imanishi J, Charoenlap C, Choong P. Intramedullary nailing has sufficient durability for metastatic femoral fractures. World J Surg Oncol. 2016;14:80 pubmed publisher
    ..Broader indication including these parts should be considered, for IMN has advantages such as lower cost and less invasiveness and even an implant failure can be revised by mega-prosthetic reconstruction. ..
  32. Glowacki J. Impact of postmenopausal osteoporosis on the oral and maxillofacial surgery patient. Oral Maxillofac Surg Clin North Am. 2007;19:187-98, vi pubmed
  33. Gehringer S, Muller M, Maierl J. [Morphological investigations of deep sole ulcers in cattle. Part 1: The complicated Rusterholz ulcer]. Tierarztl Prax Ausg G Grosstiere Nutztiere. 2017;45:5-17 pubmed publisher
    ..Changes in the bursa podotrochlearis, the common digital flexor tendon sheath and the pastern joint are assumed to develop as a consequence of arthritis in the distal joint. ..
  34. Bostel T, Förster R, Schlampp I, Sprave T, Bruckner T, Nicolay N, et al. Spinal bone metastases in colorectal cancer: a retrospective analysis of stability, prognostic factors and survival after palliative radiotherapy. Radiat Oncol. 2017;12:115 pubmed publisher
    ..To avoid unnecessary hospitalisation and improve remaining QoL, short fractionated treatment schedules of RT may be prefered in this highly palliative situation, particularly for patients with a KPS < 70%. ..
  35. Moulin P, Vaysse F, Bieth E, Mornet E, Gennero I, Dalicieux Laurencin S, et al. Hypophosphatasia may lead to bone fragility: don't miss it. Eur J Pediatr. 2009;168:783-8 pubmed publisher
    ..In conclusion, hypophosphatasia must not be forgotten as an aetiological factor of repetitive fractures or bone pain in children and AP activity should be checked accurately. ..
  36. de Souza Cruz E, da Silva Tabosa A, Falcão A, Tartari T, de Menezes L, da Costa E, et al. Use of refrigerant spray of a propane/butane/isobutane gas mixture in the management of keratocystic odontogenic tumors: a preliminary study. Oral Maxillofac Surg. 2017;21:21-26 pubmed publisher
    ..Pathologic fractures and infections were not observed. The results obtained suggest that enucleation followed by cryosurgery is an effective therapy for managing KCOT. ..
  37. Szendroi M, Antal I, Szendroi A, Lazary A, Varga P. Diagnostic algorithm, prognostic factors and surgical treatment of metastatic cancer diseases of the long bones and spine. EFORT Open Rev. 2017;2:372-381 pubmed publisher
    ..Cite this article: EFORT Open Rev 2017;2:372-381...
  38. Voggenreiter G, Brocker K, Röhrl B, Sadick M, Obertacke U. [Results of balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures]. Unfallchirurg. 2008;111:403-12 pubmed publisher
    ..However, in 26% of patients new fractures occurred, predominantly in adjacent levels but approximately 50% of these fractures were clinically asymptomatic. ..
  39. Ganesh V, Chan S, Raman S, Chow R, Hoskin P, Lam H, et al. A review of patterns of practice and clinical guidelines in the palliative radiation treatment of uncomplicated bone metastases. Radiother Oncol. 2017;124:38-44 pubmed publisher
    ..Although there is some variation between groups, the majority of guidelines recommend use of SFRT and others consider it to be a reasonable alternative to MFRT. ..
  40. Shapiro C, Moriarty J, Dusetzina S, Himelstein A, Foster J, Grubbs S, et al. Cost-Effectiveness Analysis of Monthly Zoledronic Acid, Zoledronic Acid Every 3 Months, and Monthly Denosumab in Women With Breast Cancer and Skeletal Metastases: CALGB 70604 (Alliance). J Clin Oncol. 2017;:JCO2017737437 pubmed publisher
    ..ZA every 3 months is the more CE option and more reasonable alternative to monthly denosumab...
  41. Li H, Yang Y, Zhang D, Gu G. [Particle impaction bone graft and plate internal fixation for the treatment of proximal femoral bone tumor or tumor lesion]. Zhongguo Gu Shang. 2017;30:647-650 pubmed publisher
    ..After the curettage, the residual tumor cells were treated by chemical and physical methods. By this method, the disease can be cured for a long time, and it can reduce the recurrence and resume the function of the hip joint. ..
  42. Vural F, Akad Soyer N, Özen P, Donmez A, Ocakci S, Saydam G, et al. Non-Hodgkin's lymphoma with bone involvement: a single center experience with 18 patients. Turk J Haematol. 2010;27:29-33 pubmed
    ..Radyoterapi uygulans?n veya uygulanmas?n, özellikle rituximab ile birlikte sistemik kemoterapi ya?am süresini olumlu yönde etkiler görünmektedir. ..
  43. Vermeer J, Renders G, Everts V. Osteonecrosis of the Jaw-a Bone Site-Specific Effect of Bisphosphonates. Curr Osteoporos Rep. 2016;14:219-25 pubmed publisher
    ..Gaining more insight into bone site-specific effects may help to better understand the pathogenesis ONJ, and contribute to the development of new bone site-specific anti-resorptive drugs. ..
  44. Hibberd C, Quan G. Risk Factors for Pathological Fracture and Metastatic Epidural Spinal Cord Compression in Patients With Spinal Metastases. Orthopedics. 2017;:1-8 pubmed publisher
    ..Orthopedics. 201x; xx(x):xx-xx.]...
  45. Chalhoub D, Orwoll E, Cawthon P, Ensrud K, Boudreau R, Greenspan S, et al. Areal and volumetric bone mineral density and risk of multiple types of fracture in older men. Bone. 2016;92:100-106 pubmed publisher
    ..In summary, both lower aBMD and vBMD were associated with increased fracture risk. The stronger associations observed for trabecular vBMD than cortical vBMD may reflect the greater metabolic activity of the trabecular compartment. ..
  46. Van Lenthe G, Mueller T, Wirth A, Muller R. Quantification of bone structural parameters and mechanical competence at the distal radius. J Orthop Trauma. 2008;22:S66-72 pubmed publisher
    ..The procedure can help improve predictions of fracture risk, clarify the pathophysiology of skeletal diseases, and monitor the response to therapy. ..
  47. Hosoi T. [New development in bisphosphonate treatment. Fracture prevention by bisphosphonates]. Clin Calcium. 2009;19:11-8 pubmed publisher
    ..A large scale prospective study is being conducted in Japan to answer the question whether the combination therapy with alendroate and alfacaldidol is more effective than alendronate alone to prevent fractures. ..
  48. Xu J, Zhang C. Salvage of a hip following pathological fracture through a large aneurysmal bone cyst: a case report. Hip Int. 2009;19:148-50 pubmed
    ..Instead of total hip arthroplasty, we performed one-stage reconstruction surgery combining internal fixation and free vascularized fibular grafting. At 4 years the structure and function of the hip had been preserved. ..
  49. Delvin E, Alos N, Rauch F, Marcil V, Morel S, Boisvert M, et al. Vitamin D nutritional status and bone turnover markers in childhood acute lymphoblastic leukemia survivors: A PETALE study. Clin Nutr. 2018;: pubmed publisher
    ..Furthermore, there seem to be no overt imbalance in the gender- and age-adjusted serum bone turnover marker concentrations. ..
  50. Mudgal C, Jupiter J. Plate fixation of osteoporotic fractures of the distal radius. J Orthop Trauma. 2008;22:S106-15 pubmed publisher
  51. Thomas E, Cyteval C, Herisson C, Leonard L, Blotman F. Osteoporotic fracture of the sacrum: sacroplasty and physical medecine. Ann Phys Rehabil Med. 2009;52:427-35 pubmed publisher
    ..Sacroplasty is of evident interest for elderly patients suffering of an osteoporotic fracture of sacrum. It reduces decubitus complications, secondary effects of antalgics and allows an early reeducation. ..
  52. Syversen U, Halse J. [Treatment of osteoporosis with parathyroid hormone]. Tidsskr Nor Laegeforen. 2008;128:39-41 pubmed
    ..PTH given intermittently stimulates the osteoblasts and bone formation. We here present the effect of PTH on bone metabolism, bone mineral density and fracture reduction, and discuss the role of PTH in osteoporosis treatment...
  53. Senniappan S, Elazabi A, Doughty I, Mughal M. Case 2: Fractures in under-6-month-old exclusively breast-fed infants born to immigrant parents: nonaccidental injury? (case presentation). Diagnosis: Pathological fractures secondary to vitamin D deficiency rickets in under-6-months-old, exclusively. Acta Paediatr. 2008;97:836-7, 992-3 pubmed publisher
  54. Ruhl C. Beyond bone mineral density: several factors define bone health. Nurs Womens Health. 2008;12:249-51 pubmed publisher
  55. Firoozabadi R, Morshed S, Engelke K, Prevrhal S, Fierlinger A, Miclau T, et al. Qualitative and quantitative assessment of bone fragility and fracture healing using conventional radiography and advanced imaging technologies--focus on wrist fracture. J Orthop Trauma. 2008;22:S83-90 pubmed publisher
    ..Clinically, the challenges for bone imaging include balancing the advantages of simple bone densitometry versus the more complex architectural features of bone, or the deeper research requirements versus the broader clinical needs...
  56. Leung H, Wong C, Shen W. Intramedullary nailing for adult hypophosphatasia: a case report. J Orthop Surg (Hong Kong). 2008;16:385-8 pubmed
    ..We report a 46-year-old woman who underwent multiple intramedullary nailings for fractures and deformities of 6 long bones over 13 years...
  57. Geusens P, Sambrook P, Lems W. Fracture prevention in men. Nat Rev Rheumatol. 2009;5:497-504 pubmed publisher
    ..For men with severe osteoporosis, treatment with the anabolic agent teriparatide might be an effective option...
  58. Harada H, Katagiri H, Kamata M, Yoshioka Y, Asakura H, Hashimoto T, et al. Radiological response and clinical outcome in patients with femoral bone metastases after radiotherapy. J Radiat Res. 2010;51:131-6 pubmed
    ..Our data suggest that radiotherapy can enable metastatic bone healing and avoid surgery in many lesions. However, radiological PD lesions often require surgery after radiotherapy...
  59. Selek H, Basarir K, Yildiz Y, Saglik Y. Cemented endoprosthetic replacement for metastatic bone disease in the proximal femur. J Arthroplasty. 2008;23:112-7 pubmed publisher
    ..We believe that in patients with metastatic disease in the proximal femur, endoprosthetic reconstruction can provide early and stable fixation with pain reduction and good functional results...
  60. Kaneko T, Skinner H, Keyak J. Lytic lesions in the femoral neck: Importance of location and evaluation of a novel minimally invasive repair technique. J Orthop Res. 2008;26:1127-32 pubmed publisher
    ..These findings may lead to a reduction in the number of patients who suffer a preventable pathologic fracture, a decreased likelihood of unnecessary surgery, and a less invasive prophylactic surgical procedure...
  61. Traut V. [Zoledronic acid for preventing fractures]. Internist (Berl). 2008;49:1002; author reply 1002 pubmed publisher
  62. Ofluoglu O, Ofluoglu D. A case report: pregnancy-induced severe osteoporosis with eight vertebral fractures. Rheumatol Int. 2008;29:197-201 pubmed publisher
    ..Although pregnancy-associated osteoporosis is a rare condition, when pain occurs in the last trimester or early postpartum period, it should be considered in differential diagnosis...
  63. Ensrud K, Ewing S, Cawthon P, Fink H, Taylor B, Cauley J, et al. A comparison of frailty indexes for the prediction of falls, disability, fractures, and mortality in older men. J Am Geriatr Soc. 2009;57:492-8 pubmed publisher
  64. Datir A, Pechon P, Saifuddin A. Imaging-guided percutaneous biopsy of pathologic fractures: a retrospective analysis of 129 cases. AJR Am J Roentgenol. 2009;193:504-8 pubmed publisher
  65. Yang L, Jing Y, Hong D, Chong Qi T. Valgus osteotomy combined with intramedullary nail for Shepherd's crook deformity in fibrous dysplasia: 14 femurs with a minimum of 4 years follow-up. Arch Orthop Trauma Surg. 2010;130:497-502 pubmed publisher
    ..To investigate the effectiveness of valgus osteotomy combined with intramedullary nail in treatment of Shepherd's crook deformity of fibrous dysplasia...
  66. Klostermann C, Hette K, Pflugmacher R. [Transpedicular osteotomy with dorsal wedge osteotomy: treatment of post-traumatic or postinfection kyphotic malalignment of the thoraco-lumbar spine]. Unfallchirurg. 2009;112:1041-6 pubmed publisher
  67. Suzuki H, Kamiya N, Yano M, Endo T, Takano M, Kawamura K, et al. [Bone and Men's Health. Bisphosphonate therapy for prostate cancer]. Clin Calcium. 2010;20:258-66 pubmed publisher
    ..In this review, we summarized the current understanding and therapy of bone metastasis in prostate cancer in mainly respect to Zoredronic acid use...
  68. Vande Berg B, Malghem J, Maldague B, Koutaissoff S, Simoni R, Lecouvet F. Spontaneous vertebral fracture: benign or pathological?. JBR-BTR. 2007;90:458-60 pubmed
  69. Jham B, Aguiar M, Jham A, Duraes G, Fernandes A. Successful conservative treatment of osteoradionecrosis of the mandible associated with pathological fracture. Minerva Stomatol. 2008;57:65-9 pubmed
    ..Resolution of the ulcer and fracture was observed after 6 weeks of treatment. This report shows that ORN may be conservatively managed in specific situations, with good cosmetic and functional..
  70. Guessous I, Cornuz J, Ruffieux C, Burckhardt P, Krieg M. Osteoporotic fracture risk in elderly women: estimation with quantitative heel US and clinical risk factors. Radiology. 2008;248:179-84 pubmed publisher
    ..To derive a prediction rule by using prospectively obtained clinical and bone ultrasonographic (US) data to identify elderly women at risk for osteoporotic fractures...
  71. Aslam E, Muhammad T, Sharif S. Percutaneous vertebroplasty in osteoporotic vertebral compression fractures: our initial experience. J Pak Med Assoc. 2008;58:498-501 pubmed
    ..To see the safety and efficacy of Percutaneous vertebroplasty in osteoporotic vertebral compression fractures...
  72. Shin J, Ha K, Kim K, Lee J, Joo M. Surgical treatment for delayed pyogenic spondylitis after percutaneous vertebroplasty and kyphoplasty. Report of 4 cases. J Neurosurg Spine. 2008;9:265-72 pubmed
    ..Surgical treatment requires cement removal and anterior reconstruction with or without additional posterior instrumented fusion...
  73. Spanjol J, Maricic A, Valencic M, Oguic R, Krpina K, Protic A, et al. Influence of insolation on osteoporosis progression in androgen deprived nonmetastatic prostate cancer patients. Coll Antropol. 2008;32 Suppl 2:79-81 pubmed
    ..In conclusion higher insolation in androgen deprived nonmetastatic prostate cancer patients significantly decreases the osteoporosis progression and the risk of pathologic bone fractures...
  74. Muijs S, Nieuwenhuijse M, van Erkel A, Dijkstra P. Percutaneous vertebroplasty for the treatment of osteoporotic vertebral compression fractures: evaluation after 36 months. J Bone Joint Surg Br. 2009;91:379-84 pubmed publisher
    ..Percutaneous vertebroplasty in the treatment of chronic vertebral compression fractures results in an immediate, significant and lasting reduction in back pain, and overall improvement in physical and mental health...
  75. Dorner T, Weichselbaum E, Lawrence K, Viktoria Stein K, Rieder A. Austrian Osteoporosis Report: epidemiology, lifestyle factors, public health strategies. Wien Med Wochenschr. 2009;159:221-9 pubmed publisher
    ..The data presented in the Austrian Osteoporosis Report are useful to enable the development of public health strategies and methods to help resolve some of these problems, and ultimately contribute to improved bone health in the nation...
  76. Dormuth C, Carney G, Carleton B, Bassett K, Wright J. Thiazolidinediones and fractures in men and women. Arch Intern Med. 2009;169:1395-402 pubmed publisher
    ..The association between the use of thiazolidinediones and fractures in men and women is not adequately understood...
  77. Arendse R, Brink P, Beighton P. Hereditary bone dysplasia with pathological fractures and nodal osteoarthropathy. Skeletal Radiol. 2009;38:1197-203 pubmed publisher
    ..It was not possible for molecular studies to be undertaken. Pedigree data were consistent with autosomal dominant transmission, and this disorder appeared to be a previously undocumented heritable skeletal dysplasia...
  78. Faulkner K, Chan B, Cauley J, Marshall L, Ensrud K, Stefanick M, et al. Histories including number of falls may improve risk prediction for certain non-vertebral fractures in older men. Inj Prev. 2009;15:307-11 pubmed publisher
    ..To determine whether information on number of falls on a falls history screen predicts risk of non-vertebral and hip fracture...
  79. Gunther K, Hofbauer L, Defer A, Dreinhöfer K, Duda G, Goldhahn J, et al. [Current application of osteoporosis guidelines--expert recommendations of the German Society of Orthopaedic Surgery and Traumatology]. Z Orthop Unfall. 2009;147:542-6 pubmed publisher
    ..Although evidence-based guidelines for diagnosis and treatment are available, their application in daily practice is insufficient. The aim of our initiative was to develop a strategy for supporting this transfer...
  80. McLean R. Proinflammatory cytokines and osteoporosis. Curr Osteoporos Rep. 2009;7:134-9 pubmed
    ..Additional studies are required to establish if inflammation is an important risk factor for osteoporosis...
  81. Vogel V, Costantino J, Wickerham D, Cronin W, Cecchini R, Atkins J, et al. Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing breast cancer. Cancer Prev Res (Phila). 2010;3:696-706 pubmed publisher
    ..These results have important public health implications and clarify that both raloxifene and tamoxifen are good preventive choices for postmenopausal women with elevated risk for breast cancer...
  82. Yang H, Gan M, Zou J, Mei X, Shen X, Wang G, et al. Kyphoplasty for the treatment of Kümmell's disease. Orthopedics. 2010;33:479 pubmed publisher
    ..Kyphoplasty may be a relatively safe and effective method for treatment of Kümmell's disease when modified techniques are used to prevent cement leakage and dislodgment...
  83. Miki T, Masaki H. [Daily practice using the guidelines for prevention and treatment of osteoporosis. Utilization of metabolic markers of bone in daily osteoporosis practice]. Clin Calcium. 2008;18:1127-34 pubmed publisher
    ..The follow-up evaluation of the markers is useful in patients treated with bisphosphonate, raloxifene and/or vitamin K2 to maintain adherence...
  84. Holder K, Kerley S. Alendronate for fracture prevention in postmenopause. Am Fam Physician. 2008;78:579-81 pubmed
    ..Alendronate (Fosamax) belongs to the bisphosphonate class of drugs, which act to inhibit bone resorption by interfering with the activity of osteoclasts...
  85. Insogna K. The effect of proton pump-inhibiting drugs on mineral metabolism. Am J Gastroenterol. 2009;104 Suppl 2:S2-4 pubmed publisher
    ..In the long term, this could potentially lead to a negative whole body calcium balance, resulting in higher rates of bone loss and a greater risk of fragility fractures...
  86. Sasano H, Miki Y. [Bone and Men's Health. Effects of aromatase inhibitors on human osteoblasts]. Clin Calcium. 2010;20:189-97 pubmed publisher
    ..Therefore, in this review, we will summarize in vitro effects of AIs, especially androgenic effects of steroidal AIs upon human osteoblasts in order to further understand their effects on human skeletal systems...
  87. Esen A, Dolanmaz D, Kalayci A, Gunhan O, Avunduk M. Treatment of localized Langerhans' cell histiocytosis of the mandible with intralesional steroid injection: report of a case. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:e53-8 pubmed publisher
    ..Repeated intralesional corticosteroid injections resulted in fracture line disappearance within 14 months and lesion healing by the end of the 36-month follow-up...
  88. Matus Jiménez J, Henríquez Avalos C, Lorenzini González G. [Spontaneous sternum fracture in a pathologic area. Case report and literature review]. Acta Ortop Mex. 2010;24:33-6 pubmed
    ..At 18 weeks the patient is doing fine, X-rays show grade IV healing, and he will go on to the second stage of radiotherapy...
  89. Yamada K, Kohno N. [Cancer treatment-induced bone loss. Treatment for breast cancer]. Clin Calcium. 2008;18:507-17 pubmed publisher
    ..We also explain the efficacy of using bisphosphonate or Denosumab with endocrine therapy, the latest management strategy for bone health...
  90. Fabeck L. [Treatment of osteoporotic fractures. A new approach by vertebroplasty and kyphoplasty]. Rev Med Brux. 2008;29:317-22 pubmed
  91. Payer J, Killinger Z, Brázdilová K. [Glucocorticoid-induced osteoporosis treatment algorithm]. Vnitr Lek. 2009;55:506-11 pubmed
    ..We also include a proposal for both prophylactic and therapeutic approach that takes into account the risk factors typical for long-term users of glucocorticoids...
  92. Pogorelić Z, Furlan D, Biocic M, Mestrovic J, Juric I, Todoric D. Titanium intramedullary nailing for treatment of simple bone cysts of the long bones in children. Scott Med J. 2010;55:35-8 pubmed
    ..Simple or unicameral bone cysts are common benign fluid-filled lesions usually located in the long bones of children before skeletal maturity. Pathological fracture is common, and is often the presenting feature...