colorado tick fever virus

Summary

Summary: A species of COLTIVIRUS transmitted by the tick DERMACENTOR andersonii and causing fever, chills, aching head and limbs, and often vomiting. It occurs in the northwestern United States, except the Pacific Coast.

Top Publications

  1. Napthine S, Yek C, Powell M, Brown T, Brierley I. Characterization of the stop codon readthrough signal of Colorado tick fever virus segment 9 RNA. RNA. 2012;18:241-52 pubmed publisher
    ..Here, we investigated the readthrough signal of Colorado tick fever virus (CTFV) segment 9 RNA (Seg-9)...
  2. Philipp C, Callaway C, Chu M, Huang G, Monath T, Trent D, et al. Replication of Colorado tick fever virus within human hematopoietic progenitor cells. J Virol. 1993;67:2389-95 pubmed
    Significant neutropenia, as well as thrombocytopenia and a mild anemia, occurs in patients infected with Colorado tick fever virus. In this study, human bone marrow CD34+ cells and KG-1a cells, a human hematopoietic progenitor cell line, ..
  3. Hassler D, Oehme R, Kimmig P, Dobler G. [Eyach virus: relative of the Colorado tick fever virus rediscovered in Baden-Württemberg]. Dtsch Med Wochenschr. 2003;128:1874 pubmed
  4. Attoui H, Billoir F, Biagini P, Cantaloube J, de Chesse R, De Micco P, et al. Sequence determination and analysis of the full-length genome of colorado tick fever virus, the type species of genus Coltivirus (Family Reoviridae). Biochem Biophys Res Commun. 2000;273:1121-5 pubmed publisher
    The Colorado tick fever virus (CTFV) is the type species of genus Coltivirus, family Reoviridae. Its genome consisting of 12 segments of dsRNA was completely sequenced...
  5. Mohd Jaafar F, Attoui H, de Micco P, de Lamballerie X. Termination and read-through proteins encoded by genome segment 9 of Colorado tick fever virus. J Gen Virol. 2004;85:2237-44 pubmed
    Genome segment 9 (Seg-9) of Colorado tick fever virus (CTFV) is 1884 bp long and contains a large open reading frame (ORF; 1845 nt in length overall), although a single in-frame stop codon (at nt 1052-1054) reduces the ORF coding ..
  6. Mohd Jaafar F, Attoui H, Gallian P, Biagini P, Cantaloube J, de Micco P, et al. Recombinant VP7-based enzyme-linked immunosorbent assay for detection of immunoglobulin G antibodies to Colorado tick fever virus. J Clin Microbiol. 2003;41:2102-5 pubmed
    VP6, VP7, VP9, VP10, VP11, and VP12 of Colorado tick fever virus (CTF virus), a virus member of the genus Coltivirus, family Reoviridae, were expressed in bacteria with the pGEX-4T-2 vector...
  7. Weiss S, Dabrowski P, Kurth A, Leendertz S, Leendertz F. A novel Coltivirus-related virus isolated from free-tailed bats from Côte d'Ivoire is able to infect human cells in vitro. Virol J. 2017;14:181 pubmed publisher
    ..The virus showed closest relationship with two human pathogenic viruses, Colorado tick fever virus and Eyach virus, and was able to infect various human cell lines in vitro...
  8. Fujita R, Ejiri H, Lim C, Noda S, Yamauchi T, Watanabe M, et al. Isolation and characterization of Tarumizu tick virus: A new coltivirus from Haemaphysalis flava ticks in Japan. Virus Res. 2017;242:131-140 pubmed publisher
    ..segments of TarTV appeared to encode putative orthologs or functional equivalents of viral proteins of Colorado tick fever virus (CTFV) and Eyach virus, suggesting that TarTV is the third member of the genus Coltivirus in the family ..
  9. Attoui H, Mohd Jaafar F, Biagini P, Cantaloube J, De Micco P, Murphy F, et al. Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses. Arch Virol. 2002;147:533-61 pubmed
    ..This analysis allows for the first time to propose an evolutionary rate for virus dsRNA genomes which was found to be in the order of 10(-8) to 10(-9) mutations/nt/year, a rate similar to that of dsDNA genomes...

More Information

Publications20

  1. Attoui H, Billoir F, Bruey J, De Micco P, De Lamballerie X. Serologic and molecular diagnosis of Colorado tick fever viral infections. Am J Trop Med Hyg. 1998;59:763-8 pubmed
    ..Specific IgM antibodies against a synthetic viral peptide could be detected in sera at the acute stage of the infection. Together, these results should permit the diagnosis of Coltivirus infection at any stage of the pathology...
  2. McLean R, Carey A, Kirk L, Francy D. Ecology of porcupines (Erethizon dorsatum) and Colorado tick fever virus in Rocky Mountain National Park, 1975-1977. J Med Entomol. 1993;30:236-8 pubmed
    ..Porcupines utilize the same habitats described for the CTF ecosystem in Rocky Mountain National Park and appear to be an important host for adult D. andersoni...
  3. Midoneck S, Richard J, Murray H. Colorado tick fever in a resident of New York City. Arch Fam Med. 1994;3:731-2 pubmed
    ..This case of Colorado tick fever, acquired on the Utah-Colorado border and first expressed in Manhattan, serves as a useful reminder of the importance of taking a careful travel history for national as well as international travelers...
  4. Brown S, Miller B, McLean R, Knudson D. Co-circulation of multiple Colorado tick fever virus genotypes. Am J Trop Med Hyg. 1989;40:94-101 pubmed
    ..Of the 3 CTF PAGE genotypes obtained, 2 exhibited PAGE profiles which were different from the 1985 isolates. One isolate may have resulted from the reassortment of genes from 2 of the isolates circulating at Campos Cabin in 1985...
  5. Miller D, Covell D, McLean R, Adrian W, Niezgoda M, Gustafson J, et al. Serologic survey for selected infectious disease agents in swift and kit foxes from the western United States. J Wildl Dis. 2000;36:798-805 pubmed
    ..virus, five of 117 (4%) for Jamestown Canyon virus, one of 97 (1%) for rabies virus, one of 117 (1%) for Colorado tick fever virus, and one of 117 (1%) for western equine encephalitis virus...
  6. McLean R, Shriner R, Pokorny K, Bowen G. The ecology of Colorado tick fever in Rocky Mountain National Park in 1974. III. Habitats supporting the virus. Am J Trop Med Hyg. 1989;40:86-93 pubmed
    ..Rodents were captured along transects crossing different habitats. Open stands of ponderosa pine and shrubs on dry, rocky surfaces were found to be important for maintaining CTF virus...
  7. Klasco R. Colorado tick fever. Med Clin North Am. 2002;86:435-40, ix pubmed
    ..PCR techniques have been developed that allow the diagnosis to be established from the first day of symptoms. Ribavirin may merit consideration in the appropriate clinical setting...
  8. Attoui H, De Micco P, De Lamballerie X. Complete nucleotide sequence of Colorado tick fever virus segments M6, S1 and S2. J Gen Virol. 1997;78 ( Pt 11):2895-9 pubmed
    ..the tenth (M6), eleventh (S1) and twelfth (S2) dsRNA genomic segments of the Florio strain (N-7180) of Colorado tick fever virus were determined and found to be 675, 998 and 1884 bp, respectively, in length...
  9. Johnson A, Karabatsos N, Lanciotti R. Detection of Colorado tick fever virus by using reverse transcriptase PCR and application of the technique in laboratory diagnosis. J Clin Microbiol. 1997;35:1203-8 pubmed
    ..The reverse transcriptase PCR method is a promising tool for the early diagnosis of CTF viral infection, or for ruling out CTF virus as the etiologic agent, in order to facilitate appropriate medical support...
  10. Lambert A, Kosoy O, Velez J, Russell B, Lanciotti R. Detection of Colorado Tick Fever viral RNA in acute human serum samples by a quantitative real-time RT-PCR assay. J Virol Methods. 2007;140:43-8 pubmed
    ..The quantitative real-time RT-PCR assay is efficient, sensitive and specific and as such is useful for the detection of CTF viral RNA in the diagnostic or research laboratory...
  11. Romero J, Simonsen K. Powassan encephalitis and Colorado tick fever. Infect Dis Clin North Am. 2008;22:545-59, x pubmed publisher
    ..encephalitis, a rare cause of central nervous system infection caused by the Powassan virus, and Colorado tick fever, an acute febrile illness caused by the Colorado tick fever virus common to the Rocky Mountain region of North America.