infectious bronchitis virus

Summary

Summary: A species of CORONAVIRUS causing infections in chickens and possibly pheasants. Chicks up to four weeks old are the most severely affected.

Top Publications

  1. Bing G, Liu X, Pu J, Liu Q, Wu Q, Liu J. Different genotypes of nephropathogenic infectious bronchitis viruses co-circulating in chicken population in China. Virus Genes. 2007;35:333-7 pubmed
    ..To characterize the S1 protein of infectious bronchitis virus (IBV) from China, five representative nephropathogenic IB viruses isolated from chickens in different ..
  2. Promkuntod N, Wickramasinghe I, De Vrieze G, Gr ne A, Verheije M. Contributions of the S2 spike ectodomain to attachment and host range of infectious bronchitis virus. Virus Res. 2013;177:127-37 pubmed publisher
    The spike protein is the major viral attachment protein of the avian coronavirus infectious bronchitis virus (IBV) and ultimately determines viral tropism. The S1 subunit of the spike is assumed to be required for virus attachment...
  3. Pendleton A, Machamer C. Infectious bronchitis virus 3a protein localizes to a novel domain of the smooth endoplasmic reticulum. J Virol. 2005;79:6142-51 pubmed
    ..b>Infectious bronchitis virus (IBV) ORF 3a is one such gene...
  4. Liu S, Zhang X, Wang Y, Li C, Liu Q, Han Z, et al. Evaluation of the protection conferred by commercial vaccines and attenuated heterologous isolates in China against the CK/CH/LDL/97I strain of infectious bronchitis coronavirus. Vet J. 2009;179:130-6 pubmed
    Avian infectious bronchitis virus (IBV) causes tremendous economic losses to the poultry industry worldwide. Different serotypes of this virus show little cross-protection...
  5. Chousalkar K, Cheetham B, Roberts J. LNA probe-based real-time RT-PCR for the detection of infectious bronchitis virus from the oviduct of unvaccinated and vaccinated laying hens. J Virol Methods. 2009;155:67-71 pubmed publisher
    ..study, LNA-probe based real-time PCR was designed for the detection and absolute quantification of infectious bronchitis virus (IBV) from the oviduct of unvaccinated and vaccinated hens after IBV challenge...
  6. Mase M, Kawanishi N, Ootani Y, Murayama K, Karino A, Inoue T, et al. A novel genotype of avian infectious bronchitis virus isolated in Japan in 2009. J Vet Med Sci. 2010;72:1265-8 pubmed
    ..Furthermore, none of the antisera used in this study neutralized the index isolate (JP/Ibaraki/168-1/2009) in virus neutralization tests. These results suggest that the isolates are a novel IBV genotype in Japan (designated JP-IV). ..
  7. Shi X, Zhao Y, Gao H, Jing Z, Wang M, Cui H, et al. Evaluation of recombinant fowlpox virus expressing infectious bronchitis virus S1 gene and chicken interferon-? gene for immune protection against heterologous strains. Vaccine. 2011;29:1576-82 pubmed publisher
    A recombinant fowlpox virus (rFPV-IFN?S1) that co-expressed the infectious bronchitis virus (IBV) S1 gene and the chicken interferon-? gene has been constructed...
  8. Liao Y, Wang X, Huang M, Tam J, Liu D. Regulation of the p38 mitogen-activated protein kinase and dual-specificity phosphatase 1 feedback loop modulates the induction of interleukin 6 and 8 in cells infected with coronavirus infectious bronchitis virus. Virology. 2011;420:106-16 pubmed publisher
    ..The objective of this study was to characterize cellular mechanisms exploited by coronavirus infectious bronchitis virus (IBV) to regulate the induction of two pro-inflammatory cytokines, interleukin (IL)-6 and IL-8, at the ..
  9. Mondal S, Cardona C. Genotypic and phenotypic characterization of the California 99 (Cal99) variant of infectious bronchitis virus. Virus Genes. 2007;34:327-41 pubmed
    The California 99 (Cal99) variant of infectious bronchitis virus (IBV) was first recovered in 1999 from vaccinated broiler chicken flocks in Central California...

More Information

Publications107 found, 100 shown here

  1. Chu V, McElroy L, Bauman B, Whittaker G. Fluorescence dequenching assays of coronavirus fusion. Adv Exp Med Biol. 2006;581:241-6 pubmed
  2. Ammayappan A, Upadhyay C, Gelb J, Vakharia V. Identification of sequence changes responsible for the attenuation of avian infectious bronchitis virus strain Arkansas DPI. Arch Virol. 2009;154:495-9 pubmed publisher
    b>Infectious bronchitis virus (IBV) is the causal agent of infectious bronchitis, which still remains one of the most important poultry diseases worldwide because of numerous serotypes and variants...
  3. Kuo S, Kao H, Hou M, Wang C, Lin S, Su H. Evolution of infectious bronchitis virus in Taiwan: positively selected sites in the nucleocapsid protein and their effects on RNA-binding activity. Vet Microbiol. 2013;162:408-18 pubmed publisher
    ..has been shown to underlie the sporadic emergence of new variants of coronavirus, including the infectious bronchitis virus (IBV), a highly contagious avian pathogen...
  4. Gharaibeh S. Infectious bronchitis virus serotypes in poultry flocks in Jordan. Prev Vet Med. 2007;78:317-24 pubmed
    b>Infectious bronchitis virus (IBV) causes respiratory disease in chickens all over the world. IBV has many serotypes that do not confer cross protection against each other...
  5. Martin M, Wakenell P, Woolcock P, O CONNOR B. Evaluation of the effectiveness of two infectious bronchitis virus vaccine programs for preventing disease caused by a California IBV field isolate. Avian Dis. 2007;51:584-9 pubmed
    b>Infectious bronchitis virus CA99 serotype was isolated from several broiler flocks in Northern California...
  6. Liu S, Wang Y, Ma Y, Han Z, Zhang Q, Shao Y, et al. Identification of a newly isolated avian infectious bronchitis coronavirus variant in China exhibiting affinity for the respiratory tract. Avian Dis. 2008;52:306-14 pubmed
    Twelve infectious bronchitis virus (IBV) isolates obtained from commercial chickens in China between 2005 and 2006 were characterized by reverse transcriptase-polymerase chain reaction (RT-PCR) and the sequencing of the entire S1 gene...
  7. Pohuang T, Chansiripornchai N, Tawatsin A, Sasipreeyajan J. Detection and molecular characterization of infectious bronchitis virus isolated from recent outbreaks in broiler flocks in Thailand. J Vet Sci. 2009;10:219-23 pubmed
    Thirteen field isolates of infectious bronchitis virus (IBV) were isolated from broiler flocks in Thailand between January and June 2008. The 878-bp of the S1 gene covering a hypervariable region was amplified and sequenced...
  8. Fan H, Ooi A, Tan Y, Wang S, Fang S, Liu D, et al. The nucleocapsid protein of coronavirus infectious bronchitis virus: crystal structure of its N-terminal domain and multimerization properties. Structure. 2005;13:1859-68 pubmed
    ..The 45 kDa recombinant nucleocapsid N protein of coronavirus infectious bronchitis virus (IBV) is highly sensitive to proteolysis. We obtained a stable fragment of 14...
  9. Sun C, Han Z, Ma H, Zhang Q, Yan B, Shao Y, et al. Phylogenetic analysis of infectious bronchitis coronaviruses newly isolated in China, and pathogenicity and evaluation of protection induced by Massachusetts serotype H120 vaccine against QX-like strains. Avian Pathol. 2011;40:43-54 pubmed publisher
    Seventy-eight isolates of avian infectious bronchitis virus (IBV) were obtained from different field outbreaks in China in 2009 and genotyped with 34 reference strains...
  10. Armesto M, Evans S, Cavanagh D, Abu Median A, Keep S, Britton P. A recombinant avian infectious bronchitis virus expressing a heterologous spike gene belonging to the 4/91 serotype. PLoS ONE. 2011;6:e24352 pubmed publisher
    ..Our results confirm and extend our previous findings and conclusions that swapping of the ectodomain of the S protein is a precise and effective way of generating genetically defined candidate IBV vaccines. ..
  11. Jang J, Sung H, Song C, Kwon H. Sequence analysis of the S1 glycoprotein gene of infectious bronchitis viruses: identification of a novel phylogenetic group in Korea. J Vet Sci. 2007;8:401-7 pubmed
    ..Specifically, the new Korean IBV isolates K10217-03, K3-3 and K1255-03 represented a separate group. These findings suggest that the Korean IBVs appear to be continuously evolving...
  12. Miguel B, Pharr G, Wang C. The role of feline aminopeptidase N as a receptor for infectious bronchitis virus. Brief review. Arch Virol. 2002;147:2047-56 pubmed
    ..Our objective was to determine if fAPN can serve as a receptor for infectious bronchitis virus (IBV)...
  13. Spencer K, Hiscox J. Characterisation of the RNA binding properties of the coronavirus infectious bronchitis virus nucleocapsid protein amino-terminal region. FEBS Lett. 2006;580:5993-8 pubmed publisher
  14. Yang T, Wang H, Wang X, Tang J, Gao R, Li J, et al. Multivalent DNA vaccine enhanced protection efficacy against infectious bronchitis virus in chickens. J Vet Med Sci. 2009;71:1585-90 pubmed
    For efficacious DNA vaccine development against infectious bronchitis virus (IBV), the immunogenicity of a multivalent DNA vaccine was evaluated...
  15. Lee H, Youn H, Kwon J, Lee Y, Kim J, Lee J, et al. Characterization of a novel live attenuated infectious bronchitis virus vaccine candidate derived from a Korean nephropathogenic strain. Vaccine. 2010;28:2887-94 pubmed publisher
    A nephropathogenic K2/01 strain of infectious bronchitis virus (IBV) was attenuated by 170 serial passages in embryonated chicken eggs for possible use as a future IBV vaccine strain...
  16. de Wit J, Nieuwenhuisen van Wilgen J, Hoogkamer A, Van De Sande H, Zuidam G, Fabri T. Induction of cystic oviducts and protection against early challenge with infectious bronchitis virus serotype D388 (genotype QX) by maternally derived antibodies and by early vaccination. Avian Pathol. 2011;40:463-71 pubmed publisher
    Since the end of 2003, strains of the D388 serotype (QX genotype) of infectious bronchitis virus (IBV) have caused considerable damage to the Dutch poultry industry...
  17. Brooks J, Rainer A, Parr R, Woolcock P, Hoerr F, Collisson E. Comparisons of envelope through 5B sequences of infectious bronchitis coronaviruses indicates recombination occurs in the envelope and membrane genes. Virus Res. 2004;100:191-8 pubmed
    ..Putative sites of recombination could also be identified in both the E and M ORFs of laboratory strains of IBV. ..
  18. Liu S, Kong X. A new genotype of nephropathogenic infectious bronchitis virus circulating in vaccinated and non-vaccinated flocks in China. Avian Pathol. 2004;33:321-7 pubmed
    Five strains of infectious bronchitis virus (IBV) were isolated from five layer flocks that had nephropathogenic infection in four provinces in China. Among them, three of the five flocks had been vaccinated against infectious bronchitis...
  19. Cavanagh D, Picault J, Gough R, Hess M, Mawditt K, Britton P. Variation in the spike protein of the 793/B type of infectious bronchitis virus, in the field and during alternate passage in chickens and embryonated eggs. Avian Pathol. 2005;34:20-5 pubmed publisher
    ..There was no change in pathogenicity. This is the first demonstration at gene sequence level of host-driven selection for infectious bronchitis virus.
  20. Kapczynski D, Hilt D, Shapiro D, Sellers H, Jackwood M. Protection of chickens from infectious bronchitis by in ovo and intramuscular vaccination with a DNA vaccine expressing the S1 glycoprotein. Avian Dis. 2003;47:272-85 pubmed
    We have constructed a DNA vaccine (pDKArkS1-DPI) expressing the S1 glycoprotein (Arkansas DPI) of infectious bronchitis virus (IBV) to examine protective immunity after in ovo and intramuscular DNA immunization...
  21. Liu S, Zhang Q, Chen J, Han Z, Shao Y, Kong X, et al. Identification of the avian infectious bronchitis coronaviruses with mutations in gene 3. Gene. 2008;412:12-25 pubmed publisher
    The sequence of a 6.0-kb fragment was compared in the 3'-encoding region of the genome in 27 infectious bronchitis virus (IBV) strains. All these strains have the same S-3-M-5-N gene order, as is the case for other IBVs...
  22. Alvarado I, Villegas P, El Attrache J, Brown T. Evaluation of the protection conferred by commercial vaccines against the California 99 isolate of infectious bronchitis virus. Avian Dis. 2003;47:1298-304 pubmed
    An infectious bronchitis virus (IBV) was isolated from commercial broilers from the state of California exhibiting respiratory distress, inflamed tracheas, airsaculitis, and edematous lungs...
  23. Ignjatovic J, Sapats S. Identification of previously unknown antigenic epitopes on the S and N proteins of avian infectious bronchitis virus. Arch Virol. 2005;150:1813-31 pubmed
    This paper describes mapping of antigenic and host-protective epitopes of infectious bronchitis virus proteins by assessing the ability of defined peptide regions within the S1, S2 and N proteins to elicit humoral, cell-mediated and ..
  24. Domanska Blicharz K, Minta Z, Smietanka K, Porwan T. New variant of IBV in Poland. Vet Rec. 2006;158:808 pubmed
  25. Johnson M, Pooley C, Ignjatovic J, Tyack S. A recombinant fowl adenovirus expressing the S1 gene of infectious bronchitis virus protects against challenge with infectious bronchitis virus. Vaccine. 2003;21:2730-6 pubmed
    The spike peplomer S1 subunit sequence from avian infectious bronchitis virus (IBV) Vic S strain was expressed in a plasmid under the control of the fowl adenovirus (FAV) major late promoter (MLP)...
  26. Pendleton A, Machamer C. Differential localization and turnover of infectious bronchitis virus 3b protein in mammalian versus avian cells. Virology. 2006;345:337-45 pubmed publisher
    b>Infectious bronchitis virus (IBV) 3b protein is highly conserved among group 3 coronaviruses, suggesting that it is important for infection...
  27. Armesto M, Cavanagh D, Britton P. The replicase gene of avian coronavirus infectious bronchitis virus is a determinant of pathogenicity. PLoS ONE. 2009;4:e7384 pubmed publisher
    ..have previously demonstrated that the replacement of the S gene from an avirulent strain (Beaudette) of infectious bronchitis virus (IBV) with an S gene from a virulent strain (M41) resulted in a recombinant virus (BeauR-M41(S)) with ..
  28. Han Z, Sun C, Yan B, Zhang X, Wang Y, Li C, et al. A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China. Infect Genet Evol. 2011;11:190-200 pubmed publisher
    A comprehensive study of the epidemiology and pathogenicity of infectious bronchitis virus (IBV) in China was carried out by molecular characterization of the S1 gene from 46 isolates obtained for this study and 174 reference strains ..
  29. Jones B, Hennion R. The preparation of chicken tracheal organ cultures for virus isolation, propagation, and titration. Methods Mol Biol. 2008;454:103-7 pubmed publisher
    ..A simple technique for the preparation of chicken tracheal organ cultures in glass test tubes, in which virus growth and ciliostasis can be readily observed, is described. ..
  30. Mahmood Z, Sleman R, Uthman A. Isolation and molecular characterization of Sul/01/09 avian infectious bronchitis virus, indicates the emergence of a new genotype in the Middle East. Vet Microbiol. 2011;150:21-7 pubmed publisher
    b>Infectious bronchitis virus (IBV) was isolated from trachea and kidney tissues of eight broiler farms in Kurdistan region of North Iraq from 2008 to 2010...
  31. Kwak H, Park M, Jeong S. Annexin A2 binds RNA and reduces the frameshifting efficiency of infectious bronchitis virus. PLoS ONE. 2011;6:e24067 pubmed publisher
    ..Here, we identified ANXA2 as a RNA binding protein (RBP) that binds IBV (Infectious Bronchitis Virus) pseudoknot RNA...
  32. Schikora B, Shih L, Hietala S. Genetic diversity of avian infectious bronchitis virus California variants isolated between 1988 and 2001 based on the S1 subunit of the spike glycoprotein. Arch Virol. 2003;148:115-36 pubmed
    Twenty-nine isolates of avian infectious bronchitis virus (IBV) recovered from commercial chicken flocks in California between 1988 and 2001 and identified as California variants by serotype and direct automated cycle sequencing of the ..
  33. Naqi S, Gay K, Patalla P, Mondal S, Liu R. Establishment of persistent avian infectious bronchitis virus infection in antibody-free and antibody-positive chickens. Avian Dis. 2003;47:594-601 pubmed
    Avian infectious bronchitis virus (IBV) causes a highly contagious and economically significant disease in chickens...
  34. Wang Y, Sun Y, Tian Z, Shi X, Tong G, Liu S, et al. Protection of chickens against infectious bronchitis by a recombinant fowlpox virus co-expressing IBV-S1 and chicken IFNgamma. Vaccine. 2009;27:7046-52 pubmed publisher
    A fowlpox virus expressing the chicken infectious bronchitis virus (IBV) S1 gene of the LX4 strain (rFPV-IBVS1) and a fowlpox virus co-expressing the S1 gene and the chicken type II interferon gene (rFPV-IBVS1-ChIFNgamma) were ..
  35. Sjaak de Wit J, Cook J, van der Heijden H. Infectious bronchitis virus variants: a review of the history, current situation and control measures. Avian Pathol. 2011;40:223-35 pubmed publisher
    The history, current situation and control measures for infectious bronchitis virus (IBV) variants are reviewed...
  36. Abro S, Renström L, Ullman K, Belak S, Baule C. Characterization and analysis of the full-length genome of a strain of the European QX-like genotype of infectious bronchitis virus. Arch Virol. 2012;157:1211-5 pubmed publisher
    In recent years, strains of infectious bronchitis virus belonging to the QX-like genotype have been causing huge economic losses in commercial chicken flocks in different countries in Europe...
  37. Feberwee A, Morrow C, Ghorashi S, Noormohammadi A, Landman W. Effect of a live Mycoplasma synoviae vaccine on the production of eggshell apex abnormalities induced by a M. synoviae infection preceded by an infection with infectious bronchitis virus D1466. Avian Pathol. 2009;38:333-40 pubmed publisher
    ..All groups were inoculated with infectious bronchitis virus D1466 at 18 weeks of age...
  38. Shieh H, Shien J, Chou H, Shimizu Y, Chen J, Chang P. Complete nucleotide sequences of S1 and N genes of infectious bronchitis virus isolated in Japan and Taiwan. J Vet Med Sci. 2004;66:555-8 pubmed
    ..This result high lightens the importance of development of vaccines based on the local strains of IBV. ..
  39. Gelb J, Weisman Y, Ladman B, Meir R. S1 gene characteristics and efficacy of vaccination against infectious bronchitis virus field isolates from the United States and Israel (1996 to 2000). Avian Pathol. 2005;34:194-203 pubmed
    The S1 genes of isolates of avian coronavirus infectious bronchitis virus (IBV) from commercial chickens in the US and Israel (20 isolates from each country) were studied using reverse transcription-polymerase chain reaction restriction ..
  40. Huang Y, Wang C. Development of attenuated vaccines from Taiwanese infectious bronchitis virus strains. Vaccine. 2006;24:785-91 pubmed
    ..Additionally, the TW I attenuated vaccine strain had no reversion to virulence after five back passages in chicks. In conclusion, these attenuated vaccines have potential for controlling local Taiwanese IBV infections in chickens. ..
  41. Jackwood M, Hilt D, Lee C, Kwon H, Callison S, Moore K, et al. Data from 11 years of molecular typing infectious bronchitis virus field isolates. Avian Dis. 2005;49:614-8 pubmed
    In 1993, a new molecular typing method for infectious bronchitis virus (IBV) was introduced...
  42. Terregino C, Toffan A, Beato M, De Nardi R, Vascellari M, Meini A, et al. Pathogenicity of a QX strain of infectious bronchitis virus in specific pathogen free and commercial broiler chickens, and evaluation of protection induced by a vaccination programme based on the Ma5 and 4/91 serotypes. Avian Pathol. 2008;37:487-93 pubmed publisher
    ..This study confirms that vaccination at 1 day old and at 14 days of age using the Ma5 and 4/91 IB vaccines may be instrumental in reducing the economic impact of QX IB virus infections in layer and broiler farms. ..
  43. Jackwood M, Hall D, Handel A. Molecular evolution and emergence of avian gammacoronaviruses. Infect Genet Evol. 2012;12:1305-11 pubmed publisher
    ..Within this genus of coronaviruses, the avian coronavirus infectious bronchitis virus (IBV) causes a highly infectious upper-respiratory tract disease in commercial poultry...
  44. Ziegler A, Ladman B, Dunn P, Schneider A, Davison S, Miller P, et al. Nephropathogenic infectious bronchitis in Pennsylvania chickens 1997-2000. Avian Dis. 2002;46:847-58 pubmed
    Nephropathogenic infectious bronchitis (NIB) was diagnosed in 28 infectious bronchitis virus (IBV)-vaccinated commercial chicken flocks in Pennsylvania from December 1997 to July 2000...
  45. Cavanagh D. Severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus. Avian Pathol. 2003;32:567-82 pubmed
    ..b>Infectious bronchitis virus (IBV), together with the genetically related coronaviruses of turkey (Meleagris gallopovo) and ring-..
  46. Lee S, Sung H, Kwon H. S1 glycoprotein gene analysis of infectious bronchitis viruses isolated in Korea. Arch Virol. 2004;149:481-94 pubmed
    Fifteen isolates of Infectious bronchitis virus (IBV) were obtained from the kidney, trachea, and cecal tonsil of IB suspected chickens between 2001 and 2002 years in Korea...
  47. Vandekerchove D, Herdt P, Laevens H, Butaye P, Meulemans G, Pasmans F. Significance of interactions between Escherichia coli and respiratory pathogens in layer hen flocks suffering from colibacillosis-associated mortality. Avian Pathol. 2004;33:298-302 pubmed
    ..Pooled sera, taken at the first and last sampling, were examined for antibody titres against infectious bronchitis virus (IBV) and Newcastle disease virus (NDV), and the individual sera from all four samplings were examined ..
  48. Shi P, Yu L, Fu Y, Huang J, Zhang K, Zhang Y. Evolutionary implications of Avian Infectious Bronchitis Virus (AIBV) analysis. Cell Res. 2006;16:323-7 pubmed
    ..We investigate the amino acid substitution features in the Avian Infectious Bronchitis Virus (AIBV) antigenic domain of a vaccine serotype (DE072) and a virulent viral strain (GA98) to better ..
  49. Bourogâa H, Miled K, Gribâa L, El Behi I, Ghram A. Characterization of new variants of avian infectious bronchitis virus in Tunisia. Avian Dis. 2009;53:426-33 pubmed
    Three infectious bronchitis virus (IBV) strains, isolated from suspected Tunisian broiler flocks, were characterized as variant viruses using genotyping and serotyping techniques...
  50. Zhang Y, Wang H, Wang T, Fan W, Zhang A, Wei K, et al. Complete genome sequence and recombination analysis of infectious bronchitis virus attenuated vaccine strain H120. Virus Genes. 2010;41:377-88 pubmed publisher
    The strain H120 of infectious bronchitis virus (IBV) is one of the earliest and representative attenuated live Infectious Bronchitis vaccine strains...
  51. Ruch T, Machamer C. The hydrophobic domain of infectious bronchitis virus E protein alters the host secretory pathway and is important for release of infectious virus. J Virol. 2011;85:675-85 pubmed publisher
    ..To further investigate the function of the infectious bronchitis virus (IBV) E protein, we developed a recombinant version of IBV in which the E protein was replaced by a ..
  52. Schwegmann Wessels C, Bauer S, Winter C, Enjuanes L, Laude H, Herrler G. The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus. Virol J. 2011;8:435 pubmed publisher
    ..The dependence on the sialic acid binding activity for an efficient infection differs in the analyzed TGEV strains. ..
  53. Ng L, Liu D. Membrane association and dimerization of a cysteine-rich, 16-kilodalton polypeptide released from the C-terminal region of the coronavirus infectious bronchitis virus 1a polyprotein. J Virol. 2002;76:6257-67 pubmed
    ..the identification of the most C-terminal cleavage product of the 1a polyprotein as a 16-kDa protein in infectious bronchitis virus-infected Vero cells...
  54. Boltz D, Nakai M, Bahra J. Avian infectious bronchitis virus: a possible cause of reduced fertility in the rooster. Avian Dis. 2004;48:909-15 pubmed
    ..The cause of epididymal stones is unknown, but an infectious agent, the avian infectious bronchitis virus (AIBV), has been implicated...
  55. Jayaram J, Youn S, Collisson E. The virion N protein of infectious bronchitis virus is more phosphorylated than the N protein from infected cell lysates. Virology. 2005;339:127-35 pubmed
    Because phosphorylation of the infectious bronchitis virus (IBV) nucleocapsid protein (N) may regulate its multiple roles in viral replication, the dynamics of N phosphorylation were examined...
  56. Fang S, Chen B, Tay F, Ng B, Liu D. An arginine-to-proline mutation in a domain with undefined functions within the helicase protein (Nsp13) is lethal to the coronavirus infectious bronchitis virus in cultured cells. Virology. 2007;358:136-47 pubmed publisher
    ..During construction of an infectious clone from a Vero cell-adapted coronavirus infectious bronchitis virus (IBV), we found that a G-C point mutation at nucleotide position 15526, causing Arg-to-Pro mutation at ..
  57. Li L, Xue C, Chen F, Qin J, Xie Q, Bi Y, et al. Isolation and genetic analysis revealed no predominant new strains of avian infectious bronchitis virus circulating in South China during 2004-2008. Vet Microbiol. 2010;143:145-54 pubmed publisher
    Twenty-seven strains of avian infectious bronchitis virus (IBV) were isolated from dead or diseased chickens at different chicken farms in South China during 2004-2008, of which the S1 gene was sequenced...
  58. Kuo S, Wang C, Hou M, Huang Y, Kao H, Su H. Evolution of infectious bronchitis virus in Taiwan: characterisation of RNA recombination in the nucleocapsid gene. Vet Microbiol. 2010;144:293-302 pubmed publisher
    Avian infectious bronchitis virus (IBV) belongs to the Coronaviridae family and causes significant economic loss in Taiwan (TW), even in flocks that have been extensively immunised with Massachusetts (Mass)-serotype vaccines...
  59. Ignjatovic J, Ashton D, Reece R, Scott P, Hooper P. Pathogenicity of Australian strains of avian infectious bronchitis virus. J Comp Pathol. 2002;126:115-23 pubmed
    The pathogenicity of 25 strains of infectious bronchitis virus (IBV) isolated in Australia between 1961 and 1994 was compared in white leghorn specific pathogen-free chicks...
  60. Chen H, Gill A, Dove B, Emmett S, Kemp C, Ritchie M, et al. Mass spectroscopic characterization of the coronavirus infectious bronchitis virus nucleoprotein and elucidation of the role of phosphorylation in RNA binding by using surface plasmon resonance. J Virol. 2005;79:1164-79 pubmed
    ..this hypothesis, we examined the kinetics of RNA binding between nonphosphorylated and phosphorylated infectious bronchitis virus N protein with nonviral and viral RNA by surface plasmon resonance (Biacore)...
  61. Harrison S, Tarpey I, Rothwell L, Kaiser P, Hiscox J. Lithium chloride inhibits the coronavirus infectious bronchitis virus in cell culture. Avian Pathol. 2007;36:109-14 pubmed
    The avian coronavirus infectious bronchitis virus (IBV) is a major economic pathogen of domestic poultry that, despite vaccination, causes mortality and significant losses in production...
  62. Dwars R, Matthijs M, Daemen A, van Eck J, Vervelde L, Landman W. Progression of lesions in the respiratory tract of broilers after single infection with Escherichia coli compared to superinfection with E. coli after infection with infectious bronchitis virus. Vet Immunol Immunopathol. 2009;127:65-76 pubmed publisher
    ..coli preceded 5 days earlier by an oculo-nasal and intratracheal infectious bronchitis virus (IBV) infection of either the virulent M41 strain or the H120 vaccine strain...
  63. Kapczynski D, Sellers H, Rowland G, Jackwood M. Detection of in ovo-inoculated infectious bronchitis virus by immunohistochemistry and in situ hybridization with a riboprobe in epithelial cells of the lung and cloacal bursa. Avian Dis. 2002;46:679-85 pubmed
    In situ hybridization and immunohistochemistry were utilized to identify tissues infected in ovo with infectious bronchitis virus (IBV)...
  64. Landman W, Feberwee A. Aerosol-induced Mycoplasma synoviae arthritis: the synergistic effect of infectious bronchitis virus infection. Avian Pathol. 2004;33:591-8 pubmed
    The effect of infectious bronchitis virus (IBV) infection (10(4.5) median embryo infective dose per chick) on the induction of Mycoplasma synoviae arthritis was investigated...
  65. Beato M, De Battisti C, Terregino C, Drago A, Capua I, Ortali G. Evidence of circulation of a Chinese strain of infectious bronchitis virus (QXIBV) in Italy. Vet Rec. 2005;156:720 pubmed
  66. Fang S, Shen H, Wang J, Tay F, Liu D. Functional and genetic studies of the substrate specificity of coronavirus infectious bronchitis virus 3C-like proteinase. J Virol. 2010;84:7325-36 pubmed publisher
    ..we investigate the effects of amino acid substitution at the P1 position of 3CLpro cleavage sites of infectious bronchitis virus (IBV) on the cleavage efficiency and viral replication by in vitro cleavage assays and reverse genetic ..
  67. Yin J, Li G, Li J, Yang Q, Ren X. In vitro and in vivo effects of Houttuynia cordata on infectious bronchitis virus. Avian Pathol. 2011;40:491-8 pubmed publisher
    Avian infectious bronchitis virus (IBV), a coronavirus, causes infectious bronchitis leading to enormous economic loss in the poultry industry worldwide...
  68. Liu G, Lv L, Yin L, Li X, Luo D, Liu K, et al. Assembly and immunogenicity of coronavirus-like particles carrying infectious bronchitis virus M and S proteins. Vaccine. 2013;31:5524-30 pubmed publisher
    b>Infectious bronchitis virus (IBV) as an avian coronavirus is still posing a persistent and imminent threat to the poultry industry worldwide...
  69. Maier H, Hawes P, Cottam E, Mantell J, Verkade P, Monaghan P, et al. Infectious bronchitis virus generates spherules from zippered endoplasmic reticulum membranes. MBio. 2013;4:e00801-13 pubmed publisher
    ..Here we describe a detailed study of the membrane rearrangements induced by the avian gammacoronavirus infectious bronchitis virus (IBV) in a mammalian cell line but also in primary avian cells and in epithelial cells of ex vivo ..
  70. Lee C, Hilt D, Jackwood M. Typing of field isolates of infectious bronchitis virus based on the sequence of the hypervariable region in the S1 gene. J Vet Diagn Invest. 2003;15:344-8 pubmed
    ..developed that amplifies a region covering hypervariable region (HVR) 1 and HVR 2 in the S1 gene of the infectious bronchitis virus (IBV)...
  71. Ganapathy K, Cargill P, Jones R. Effects of cold storage on detection of avian infectious bronchitis virus in chicken carcasses and local antibodies in tracheal washes. J Virol Methods. 2005;126:87-90 pubmed
    In order to test the survivability of infectious bronchitis virus (IBV) in dead chicken carcasses during 24 h of cold storage, 7 week-old specific-pathogen-free chickens were infected with virulent IBV Massachusetts strain M41, and were ..
  72. Madu I, Chu V, Lee H, Regan A, Bauman B, Whittaker G. Heparan sulfate is a selective attachment factor for the avian coronavirus infectious bronchitis virus Beaudette. Avian Dis. 2007;51:45-51 pubmed
    The avian coronavirus infectious bronchitis virus (IBV) strain Beaudette is an embryo-adapted virus that has extended species tropism in cell culture...
  73. Shen H, Fang S, Chen B, Chen G, Tay F, Liu D. Towards construction of viral vectors based on avian coronavirus infectious bronchitis virus for gene delivery and vaccine development. J Virol Methods. 2009;160:48-56 pubmed publisher
    ..By using an infectious cloning system developed recently for the avian coronavirus infectious bronchitis virus (IBV), the enhanced green fluorescent protein (EGFP) gene, the firefly luciferase gene and several host ..
  74. Krapez U, Slavec B, Rojs O. Circulation of infectious bronchitis virus strains from Italy 02 and QX genotypes in Slovenia between 2007 and 2009. Avian Dis. 2011;55:155-61 pubmed
    ..These strains shared five specific amino acid substitutions that became fixed during the period of surveillance. Strains from the QX genotype that shared one specific amino acid substitution also form a separate genetic cluster. ..
  75. Feng J, Hu Y, Ma Z, Yu Q, Zhao J, Liu X, et al. Virulent avian infectious bronchitis virus, People's Republic of China. Emerg Infect Dis. 2012;18:1994-2001 pubmed publisher
    A virulent avian infectious bronchitis virus (IBV) was isolated from 30-day-old broiler chickens that exhibited respiratory symptoms, nephropathologic lesions, and a high proportion of deaths in the People's Republic of China during 2005...
  76. Shen S, Wen Z, Liu D. Emergence of a coronavirus infectious bronchitis virus mutant with a truncated 3b gene: functional characterization of the 3b protein in pathogenesis and replication. Virology. 2003;311:16-27 pubmed
    ..These results suggest that the 3b gene product is not essential for the replication of IBV. ..
  77. Li F, Tam J, Liu D. Cell cycle arrest and apoptosis induced by the coronavirus infectious bronchitis virus in the absence of p53. Virology. 2007;365:435-45 pubmed
    ..In this study, we demonstrate that infection with coronavirus infectious bronchitis virus (IBV) imposed a growth-inhibitory effect on cultured cells by inducing cell cycle arrest at S and G(2)/..
  78. Yamada Y, Liu D. Proteolytic activation of the spike protein at a novel RRRR/S motif is implicated in furin-dependent entry, syncytium formation, and infectivity of coronavirus infectious bronchitis virus in cultured cells. J Virol. 2009;83:8744-58 pubmed publisher
    The spike (S) protein of the coronavirus (CoV) infectious bronchitis virus (IBV) is cleaved into S1 and S2 subunits at the furin consensus motif RRFRR(537)/S in virus-infected cells...
  79. Liu S, Zhang X, Wang Y, Li C, Han Z, Shao Y, et al. Molecular characterization and pathogenicity of infectious bronchitis coronaviruses: complicated evolution and epidemiology in china caused by cocirculation of multiple types of infectious bronchitis coronaviruses. Intervirology. 2009;52:223-34 pubmed publisher
    ..Cocirculation of multiple types of IBV in field conditions in China renders its epidemiology and evolution very complicated, indicating the necessity for development of new vaccines or vaccine strategies. ..
  80. Guo Z, Wang H, Yang T, Wang X, Lu D, Li Y, et al. Priming with a DNA vaccine and boosting with an inactivated vaccine enhance the immune response against infectious bronchitis virus. J Virol Methods. 2010;167:84-9 pubmed publisher
    ..immunization with inactivated vaccines have been used widely to increase antibody protection against infectious bronchitis virus (IBV). However, compared with DNA vaccines, these methods usually induce poor cellular responses...
  81. Benyeda Z, Szeredi L, Mato T, Süveges T, Balka G, Abonyi Tóth Z, et al. Comparative histopathology and immunohistochemistry of QX-like, Massachusetts and 793/B serotypes of infectious bronchitis virus infection in chickens. J Comp Pathol. 2010;143:276-83 pubmed publisher
    ..experimentally the pathogenicity and tissue distribution of the recently emerged QX-like strain of infectious bronchitis virus (IBV) with the widespread M41 and 793/B serotypes of the virus...
  82. Pohuang T, Chansiripornchai N, Tawatsin A, Sasipreeyajan J. Sequence analysis of S1 genes of infectious bronchitis virus isolated in Thailand during 2008-2009: identification of natural recombination in the field isolates. Virus Genes. 2011;43:254-60 pubmed publisher
    ..The results indicated that the recombination events occurred in the S1 gene between the field strains. Based on these facts, the field IBV in Thailand has undergone genetic recombination. ..
  83. Cook J, Jackwood M, Jones R. The long view: 40 years of infectious bronchitis research. Avian Pathol. 2012;41:239-50 pubmed publisher
    ..b>Infectious bronchitis virus is a significant pathogen in the domestic chicken, affecting the respiratory and renal systems as well ..
  84. Dove B, Cavanagh D, Britton P. Presence of an encephalomyocarditis virus internal ribosome entry site sequence in avian infectious bronchitis virus defective RNAs abolishes rescue by helper virus. J Virol. 2004;78:2711-21 pubmed
    Avian infectious bronchitis virus (IBV) defective RNAs (D-RNAs) have been used for the expression of heterologous genes in a helper-virus-dependent expression system...
  85. Bochkov Y, Tosi G, Massi P, Drygin V. Phylogenetic analysis of partial S1 and N gene sequences of infectious bronchitis virus isolates from Italy revealed genetic diversity and recombination. Virus Genes. 2007;35:65-71 pubmed publisher
    A total of ten infectious bronchitis virus (IBV) isolates collected from commercial chickens in Italy in 1999 were characterized by RT-PCR and sequencing of the S1 and N genes...
  86. Gough R, Cox W, de B Welchman D, Worthington K, Jones R. Chinese QX strain of infectious bronchitis virus isolated in the UK. Vet Rec. 2008;162:99-100 pubmed
  87. Chen H, Huang Y, Wang C. Identification of Taiwan and China-like recombinant avian infectious bronchitis viruses in Taiwan. Virus Res. 2009;140:121-9 pubmed publisher
    b>Infectious bronchitis virus (IBV) infections in poultry cause great economic losses to the poultry industry worldwide. The emergence of viral variants complicates disease control...
  88. Emmott E, Smith C, Emmett S, Dove B, Hiscox J. Elucidation of the avian nucleolar proteome by quantitative proteomics using SILAC and changes in cells infected with the coronavirus infectious bronchitis virus. Proteomics. 2010;10:3558-62 pubmed publisher
    ..in the absence and presence of virus, in this case the positive strand RNA virus, avian coronavirus infectious bronchitis virus. Data sets, potential protein changes and the functional consequences of virus infection were validated ..
  89. Lim T, Lee H, Lee D, Lee Y, Park J, Youn H, et al. An emerging recombinant cluster of nephropathogenic strains of avian infectious bronchitis virus in Korea. Infect Genet Evol. 2011;11:678-85 pubmed publisher
    The infectious bronchitis virus (IBV) is continuously evolving through point mutation and recombination of their genome, subsequently the emergence of IBV variants complicates disease control...
  90. Hughes A. Recombinational histories of avian infectious bronchitis virus and turkey coronavirus. Arch Virol. 2011;156:1823-9 pubmed publisher
    ..The latter hypothesis was supported by a phylogeny of S proteins from representative coronaviruses, in which S proteins of AIBV and TCoV fell in the same clade. ..
  91. Mo M, Huang B, Wei P, Wei T, Chen Q, Wang X, et al. Complete genome sequences of two Chinese virulent avian coronavirus infectious bronchitis virus variants. J Virol. 2012;86:10903-4 pubmed publisher
    Avian coronavirus infectious bronchitis virus (IBV) is variable, which causes many serotypes. Here we reported the complete genome sequences of two virulent IBV variants from China, GX-YL5 and GX-YL9, belonging to different serotypes...
  92. Ladman B, Loupos A, Gelb J. Infectious bronchitis virus S1 gene sequence comparison is a better predictor of challenge of immunity in chickens than serotyping by virus neutralization. Avian Pathol. 2006;35:127-33 pubmed
    Five strains of infectious bronchitis virus isolated from commercial chickens from the state of Pennsylvania, USA during the years 1998 and 1999 were studied...