vesicular stomatitis indiana virus

Summary

Summary: The type species of VESICULOVIRUS causing a disease symptomatically similar to FOOT-AND-MOUTH DISEASE in cattle, horses, and pigs. It may be transmitted to other species including humans, where it causes influenza-like symptoms.

Top Publications

  1. Roth S, Whittaker G. Promotion of vesicular stomatitis virus fusion by the endosome-specific phospholipid bis(monoacylglycero)phosphate (BMP). FEBS Lett. 2011;585:865-9 pubmed publisher
    ..Our data provide a biological rationale for a two-step infection reaction during VSV entry, and suggest that BMP preferentially affects the ability of VSV G to mediate lipid mixing during membrane fusion...
  2. Roche S, Rey F, Gaudin Y, Bressanelli S. Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G. Science. 2007;315:843-8 pubmed publisher
    ..A large number of G glycoproteins, perhaps organized as in the crystals, act cooperatively to induce membrane merging...
  3. Ahmed M, Marino T, Puckett S, Kock N, Lyles D. Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus. J Virol. 2008;82:9273-7 pubmed publisher
    ..These results support the use of M protein mutants of VSV as vaccine vectors...
  4. Roche S, Bressanelli S, Rey F, Gaudin Y. Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G. Science. 2006;313:187-91 pubmed publisher
    ..The structure provides a framework for understanding the reversibility of the G conformational change. Unexpectedly, G is homologous to gB of herpesviruses, which raises important questions on viral evolution...
  5. Green T, Zhang X, Wertz G, Luo M. Structure of the vesicular stomatitis virus nucleoprotein-RNA complex. Science. 2006;313:357-60 pubmed publisher
    ..This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary...
  6. Faria P, Chakraborty P, Levay A, Barber G, Ezelle H, Enninga J, et al. VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway. Mol Cell. 2005;17:93-102 pubmed
    ..Thus, these results demonstrate that VSV M protein blocks mRNA export by disrupting Rae1 function, which can be reverted by induction of Rae1 expression. ..
  7. Chandran K, Sullivan N, Felbor U, Whelan S, Cunningham J. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science. 2005;308:1643-5 pubmed publisher
    ..CatB and CatB/CatL inhibitors diminish the multiplication of infectious EboV-Zaire in cultured cells and may merit investigation as anti-EboV drugs...
  8. Grdzelishvili V, Smallwood S, Tower D, Hall R, Hunt D, Moyer S. A single amino acid change in the L-polymerase protein of vesicular stomatitis virus completely abolishes viral mRNA cap methylation. J Virol. 2005;79:7327-37 pubmed publisher
    ..Sequence analysis suggests that an aspartic acid at amino acid 1671 is a critical residue within a putative conserved S-adenosyl-l-methionine-binding domain of the L protein...
  9. Garbutt M, Liebscher R, Wahl Jensen V, Jones S, Möller P, Wagner R, et al. Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses. J Virol. 2004;78:5458-65 pubmed
    ..Our data suggest that the recombinant VSV can be used to study the role of the viral glycoproteins in virus replication, immune response, and pathogenesis...

Detail Information

Publications67

  1. Roth S, Whittaker G. Promotion of vesicular stomatitis virus fusion by the endosome-specific phospholipid bis(monoacylglycero)phosphate (BMP). FEBS Lett. 2011;585:865-9 pubmed publisher
    ..Our data provide a biological rationale for a two-step infection reaction during VSV entry, and suggest that BMP preferentially affects the ability of VSV G to mediate lipid mixing during membrane fusion...
  2. Roche S, Rey F, Gaudin Y, Bressanelli S. Structure of the prefusion form of the vesicular stomatitis virus glycoprotein G. Science. 2007;315:843-8 pubmed publisher
    ..A large number of G glycoproteins, perhaps organized as in the crystals, act cooperatively to induce membrane merging...
  3. Ahmed M, Marino T, Puckett S, Kock N, Lyles D. Immune response in the absence of neurovirulence in mice infected with m protein mutant vesicular stomatitis virus. J Virol. 2008;82:9273-7 pubmed publisher
    ..These results support the use of M protein mutants of VSV as vaccine vectors...
  4. Roche S, Bressanelli S, Rey F, Gaudin Y. Crystal structure of the low-pH form of the vesicular stomatitis virus glycoprotein G. Science. 2006;313:187-91 pubmed publisher
    ..The structure provides a framework for understanding the reversibility of the G conformational change. Unexpectedly, G is homologous to gB of herpesviruses, which raises important questions on viral evolution...
  5. Green T, Zhang X, Wertz G, Luo M. Structure of the vesicular stomatitis virus nucleoprotein-RNA complex. Science. 2006;313:357-60 pubmed publisher
    ..This serves to protect the RNA in the absence of polynucleotide synthesis. For the RNA to be accessed, some conformational change in the N protein should be necessary...
  6. Faria P, Chakraborty P, Levay A, Barber G, Ezelle H, Enninga J, et al. VSV disrupts the Rae1/mrnp41 mRNA nuclear export pathway. Mol Cell. 2005;17:93-102 pubmed
    ..Thus, these results demonstrate that VSV M protein blocks mRNA export by disrupting Rae1 function, which can be reverted by induction of Rae1 expression. ..
  7. Chandran K, Sullivan N, Felbor U, Whelan S, Cunningham J. Endosomal proteolysis of the Ebola virus glycoprotein is necessary for infection. Science. 2005;308:1643-5 pubmed publisher
    ..CatB and CatB/CatL inhibitors diminish the multiplication of infectious EboV-Zaire in cultured cells and may merit investigation as anti-EboV drugs...
  8. Grdzelishvili V, Smallwood S, Tower D, Hall R, Hunt D, Moyer S. A single amino acid change in the L-polymerase protein of vesicular stomatitis virus completely abolishes viral mRNA cap methylation. J Virol. 2005;79:7327-37 pubmed publisher
    ..Sequence analysis suggests that an aspartic acid at amino acid 1671 is a critical residue within a putative conserved S-adenosyl-l-methionine-binding domain of the L protein...
  9. Garbutt M, Liebscher R, Wahl Jensen V, Jones S, Möller P, Wagner R, et al. Properties of replication-competent vesicular stomatitis virus vectors expressing glycoproteins of filoviruses and arenaviruses. J Virol. 2004;78:5458-65 pubmed
    ..Our data suggest that the recombinant VSV can be used to study the role of the viral glycoproteins in virus replication, immune response, and pathogenesis...