parainfluenza virus 5


Summary: A species of RUBULAVIRUS originally isolated from cultured primary monkey cells. Its natural host is the DOG in which it causes kennel cough, but it can also infect humans.

Top Publications

  1. Liu C, Li X, Zhang J, Yang L, Li F, Deng J, et al. Isolation and genomic characterization of a canine parainfluenza virus type 5 strain in China. Arch Virol. 2017;162:2337-2344 pubmed publisher
    ..Phylogenetic analysis based on the complete virus genome and the P, F, and HN genes showed that HeN0718 was genetically closest to D277, a Korean strain that was isolated in 2008. ..
  2. Phan S, Zengel J, Wei H, Li Z, Wang D, He B. Parainfluenza Virus 5 Expressing Wild-Type or Prefusion Respiratory Syncytial Virus (RSV) Fusion Protein Protects Mice and Cotton Rats from RSV Challenge. J Virol. 2017;91: pubmed publisher
    ..There is no licensed vaccine. We previously generated a parainfluenza virus 5 (PIV5)-vectored vaccine candidate expressing the RSV fusion protein (F) that was immunogenic and ..
  3. Phan S, Adam C, Chen Z, Citron M, Liang X, Espeseth A, et al. Genetic Stability of Parainfluenza Virus 5-Vectored Human Respiratory Syncytial Virus Vaccine Candidates after In Vitro and In Vivo Passage. J Virol. 2017;91: pubmed publisher
    ..Previously, we developed two parainfluenza virus 5 (PIV5)-based RSV vaccine candidates that protect mice against RSV challenge...