peste des petits ruminants virus

Summary

Summary: A species of MORBILLIVIRUS causing a severe, often fatal enteritis and pneumonia (PESTE-DES-PETITS-RUMINANTS) in sheep and goats.

Top Publications

  1. Singh R, Saravanan P, Sreenivasa B, Singh R, Bandyopadhyay S. Prevalence and distribution of peste des petits ruminants virus infection in small ruminants in India. Rev Sci Tech. 2004;23:807-19 pubmed
    ..These findings may be correlated with variations in the sheep and goat husbandry practices within different geographic regions, the topography of different states and the socio-economic status of individual Indian farmers...
  2. Khan H, Siddique M, Sajjad Ur Rahman -, Abubakar M, Ashraf M. The detection of antibody against peste des petits ruminants virus in sheep, goats, cattle and buffaloes. Trop Anim Health Prod. 2008;40:521-7 pubmed publisher
  3. Balamurugan V, Sen A, Saravanan P, Singh R, Singh R, Rasool T, et al. One-step multiplex RT-PCR assay for the detection of peste des petits ruminants virus in clinical samples. Vet Res Commun. 2006;30:655-66 pubmed
    ..multiplex RT-PCR was standardized to amplify both 337 bp and 191 bp fragments of N and M genes of peste des petits ruminants virus (PPRV), respectively, and only a 337 bp fragment of N gene of Rinderpest virus (RPV)...
  4. Pawar R, raj G, Kumar T, Raja A, Balachandran C. Effect of siRNA mediated suppression of signaling lymphocyte activation molecule on replication of peste des petits ruminants virus in vitro. Virus Res. 2008;136:118-23 pubmed publisher
    ..SLAM) expression was inhibited in B95a cell line using siRNA and the effect of SLAM inhibition on peste des petits ruminants virus (PPRV) replication and infectivity titre was studied...
  5. Sen A, Saravanan P, Balamurugan V, Rajak K, Sudhakar S, Bhanuprakash V, et al. Vaccines against peste des petits ruminants virus. Expert Rev Vaccines. 2010;9:785-96 pubmed publisher
    ..Here, we discuss available potent PPR vaccines and the future possibility of developing new-generation vaccines against PPR...
  6. Abraham G, Sintayehu A, Libeau G, Albina E, Roger F, Laekemariam Y, et al. Antibody seroprevalences against peste des petits ruminants (PPR) virus in camels, cattle, goats and sheep in Ethiopia. Prev Vet Med. 2005;70:51-7 pubmed
    ..The animals had not been vaccinated against rinderpest or PPR. Antibody seroprevalences detected in camels, cattle, goats and sheep confirmed natural transmission of PPR virus under field conditions...
  7. Kul O, Kabakci N, Ozkul A, Kalender H, Atmaca H. Concurrent peste des petits ruminants virus and pestivirus infection in stillborn twin lambs. Vet Pathol. 2008;45:191-6 pubmed publisher
    Concurrent infection with peste des petits ruminants virus (PPRV) and pestivirus was diagnosed in stillborn twin lambs...
  8. Sinnathamby G, Renukaradhya G, Rajasekhar M, Nayak R, Shaila M. Immune responses in goats to recombinant hemagglutinin-neuraminidase glycoprotein of Peste des petits ruminants virus: identification of a T cell determinant. Vaccine. 2001;19:4816-23 pubmed
    b>Peste des petits ruminants virus (PPRV), a member of the genus Morbillivirus within the family Paramyxoviridae, causes a fatal disease 'peste des petits ruminants' in goats and sheep...
  9. Zhai J, Dou Y, Zhang H, Mao L, Meng X, Luo X, et al. [Construction and sequencing of full-length cDNA of peste des petits ruminants virus]. Bing Du Xue Bao. 2010;26:315-21 pubmed
    To develop a reverse genetics system of Peste des petits ruminants virus(PPRV), five pairs of oligonucleotide primers were designed on the basis of the full-length genomic sequence of PPRV Nigeria 75/ 1 strain...

More Information

Publications84

  1. Renukaradhya G, Sinnathamby G, Seth S, Rajasekhar M, Shaila M. Mapping of B-cell epitopic sites and delineation of functional domains on the hemagglutinin-neuraminidase protein of peste des petits ruminants virus. Virus Res. 2002;90:171-85 pubmed
    ..A recombinant baculovirus expressing membrane bound form of hemagglutinin-neuraminidase (HN) protein of peste des petits ruminants virus (PPRV) was employed to generate monoclonal antibodies (mAbs) against PPRV-HN protein...
  2. Bodjo S, Lelenta M, Couacy Hymann E, Kwiatek O, Albina E, Gargani D, et al. Mapping the Peste des Petits Ruminants virus nucleoprotein: identification of two domains involved in protein self-association. Virus Res. 2008;131:23-32 pubmed
    ..Here, we report on the cloning of the Peste des Petits Ruminants virus (PPRV) N gene into the baculovirus vector and the expression of the protein in insect cells...
  3. Couacy Hymann E, Roger F, Hurard C, Guillou J, Libeau G, Diallo A. Rapid and sensitive detection of peste des petits ruminants virus by a polymerase chain reaction assay. J Virol Methods. 2002;100:17-25 pubmed
    ..of about 350 bp in the 3' end of the RNA messenger that encodes the nucleocapsid protein of the peste des petits ruminants virus. The PCR-product was detected by UV illumination after electrophoresis on agarose gel or by ..
  4. Gulyaz V, Ozkul A. Pathogenicity of a local peste des petits ruminants virus isolate in sheep in Turkey. Trop Anim Health Prod. 2005;37:541-7 pubmed
  5. Awa D, Njoya A, Ngo Tama A. Economics of prophylaxis against peste des petits ruminants and gastrointestinal helminthosis in small ruminants in north Cameroon. Trop Anim Health Prod. 2000;32:391-403 pubmed
    ..A national or even a regional vaccination campaign against PPR and strategic anthelmintic treatment of small ruminants are recommended. ..
  6. Forsyth M, Barrett T. Evaluation of polymerase chain reaction for the detection and characterisation of rinderpest and peste des petits ruminants viruses for epidemiological studies. Virus Res. 1995;39:151-63 pubmed
    ..Sequencing the PCR products enabled us to examine the genetic relationships between new and previous field isolates from different geographical areas. ..
  7. Libeau G, Prehaud C, Lancelot R, Colas F, Guerre L, Bishop D, et al. Development of a competitive ELISA for detecting antibodies to the peste des petits ruminants virus using a recombinant nucleoprotein. Res Vet Sci. 1995;58:50-5 pubmed
    ..based on the reaction between a monoclonal antibody (mAb) and a recombinant nucleoprotein of the peste des petits ruminants virus (PPRV) was developed...
  8. Wang Z, Bao J, Wu X, Liu Y, Li L, Liu C, et al. Peste des petits ruminants virus in Tibet, China. Emerg Infect Dis. 2009;15:299-301 pubmed
    Serologic and molecular evidence indicates that peste des petits ruminants virus (PPRV) infection has emerged in goats and sheep in the Ngari region of southwestern Tibet, People's Republic of China...
  9. Diop M, Sarr J, Libeau G. Evaluation of novel diagnostic tools for peste des petits ruminants virus in naturally infected goat herds. Epidemiol Infect. 2005;133:711-7 pubmed
    ..Antibodies were shown to impair the RP heterologous vaccination. This evaluation offers new prospects for diagnosis and management of PPRV infection as well as for RPV control...
  10. Kwiatek O, Minet C, Grillet C, Hurard C, Carlsson E, Karimov B, et al. Peste des petits ruminants (PPR) outbreak in Tajikistan. J Comp Pathol. 2007;136:111-9 pubmed
    ..The study demonstrated (1) the value of the N gene as a target in comparing isolates obtained over an extended period of evolution, and (2) that clustering was related to the geographical origin of strains...
  11. Banyard A, Parida S, Batten C, Oura C, Kwiatek O, Libeau G. Global distribution of peste des petits ruminants virus and prospects for improved diagnosis and control. J Gen Virol. 2010;91:2885-97 pubmed publisher
    ..Across the developing world, viral pathogens such as peste des petits ruminants virus (PPRV) place a huge disease burden on agriculture, in particular affecting small ruminant production ..
  12. Haroun M, Hajer I, Mukhtar M, Ali B. Detection of antibodies against peste des petits ruminants virus in sera of cattle, camels, sheep and goats in Sudan. Vet Res Commun. 2002;26:537-41 pubmed
    Detection of antibodies against peste des petits ruminants virus in sera of cattle, camels, sheep and goats in Sudan.
  13. Mondal B, Sreenivasa B, Dhar P, Singh R, Bandyopadhyay S. Apoptosis induced by peste des petits ruminants virus in goat peripheral blood mononuclear cells. Virus Res. 2001;73:113-9 pubmed
    The ability of peste des petits ruminants virus (PPRV) to induce apoptosis in goat peripheral blood mononuclear cell (PBMC) culture was investigated...
  14. Nanda Y, Chatterjee A, Purohit A, Diallo A, Innui K, Sharma R, et al. The isolation of peste des petits ruminants virus from northern India. Vet Microbiol. 1996;51:207-16 pubmed
    ..rinderpest-like disease afflicting sheep and goats in three states of northern India was confirmed as peste des petits ruminants virus. To differentiate the virus from rinderpest a number of diagnostic tests were used, including ..
  15. Rahaman A, Srinivasan N, Shamala N, Shaila M. The fusion core complex of the peste des petits ruminants virus is a six-helix bundle assembly. Biochemistry. 2003;42:922-31 pubmed
    We describe the properties of the two heptad repeats (HR1 and HR2) of the Peste des petits ruminants virus (PPRV) fusion protein (F) to obtain insights into the mechanism by which these repeats influence PPRV-mediated cell fusion...
  16. Bao J, Li L, Wang Z, Barrett T, Suo L, Zhao W, et al. Development of one-step real-time RT-PCR assay for detection and quantitation of peste des petits ruminants virus. J Virol Methods. 2008;148:232-6 pubmed publisher
    ..real-time quantitative reverse transcription PCR (qRT-PCR) has been described for the detection of peste des petits ruminants virus (PPRV). Primers and probe were designed based on the nucleocapsid protein gene sequence...
  17. Ozkul A, Akca Y, Alkan F, Barrett T, Karaoglu T, Dagalp S, et al. Prevalence, distribution, and host range of Peste des petits ruminants virus, Turkey. Emerg Infect Dis. 2002;8:708-12 pubmed
    b>Peste des petits ruminants virus (PPRV, genus Morbillivirus), which causes a severe disease in sheep and goats, has only recently been officially declared to be present in Turkey...
  18. Mahapatra M, Parida S, Baron M, Barrett T. Matrix protein and glycoproteins F and H of Peste-des-petits-ruminants virus function better as a homologous complex. J Gen Virol. 2006;87:2021-9 pubmed
    ..The neutralizing-antibody titre on the day of challenge was approximately 17 times higher than that in the RPV-PPRFH group, indicating RPV-PPRMFH as a promising marker-vaccine candidate...
  19. Seth S, Shaila M. The fusion protein of Peste des petits ruminants virus mediates biological fusion in the absence of hemagglutinin-neuraminidase protein. Virology. 2001;289:86-94 pubmed
    To study the process of membrane fusion in Morbilliviruses, the fusion (F) glycoproteins of Peste des petits ruminants virus (PPRV) and Rinderpest virus (RPV) were expressed transiently in mammalian cells...
  20. Bailey D, Banyard A, Dash P, Ozkul A, Barrett T. Full genome sequence of peste des petits ruminants virus, a member of the Morbillivirus genus. Virus Res. 2005;110:119-24 pubmed publisher
    b>Peste des petits ruminants virus (PPRV) causes an acute febrile illness in small ruminant species, mostly sheep and goats...
  21. Dechamma H, Dighe V, Kumar C, Singh R, Jagadish M, Kumar S. Identification of T-helper and linear B epitope in the hypervariable region of nucleocapsid protein of PPRV and its use in the development of specific antibodies to detect viral antigen. Vet Microbiol. 2006;118:201-11 pubmed
    ..The antipeptide antibodies developed against this region showed specificity to PPRV antigen differentiating it from RPV when used in indirect ELISA and western blot analysis...
  22. Ismail T, Yamanaka M, Saliki J, el Kholy A, Mebus C, Yilma T. Cloning and expression of the nucleoprotein of peste des petits ruminants virus in baculovirus for use in serological diagnosis. Virology. 1995;208:776-8 pubmed
    ..The recombinant protein was used successfully as a coating antigen in an enzyme-linked immunosorbent assay for the serological diagnosis of PPRV...
  23. Roeder P, Abraham G, Kenfe G, Barrett T. Peste des petits ruminants in Ethiopian goats. Trop Anim Health Prod. 1994;26:69-73 pubmed
    ..Both morbidity and mortality rates were high in goats but sheep were not affected. ..
  24. Dhar P, Sreenivasa B, Barrett T, Corteyn M, Singh R, Bandyopadhyay S. Recent epidemiology of peste des petits ruminants virus (PPRV). Vet Microbiol. 2002;88:153-9 pubmed
    ..The possibility that its earlier presence in northern India was masked by the circulation of Rinderpest virus, a related virus of cattle, is considered unlikely...
  25. Rahman M, Shaila M, Gopinathan K. Baculovirus display of fusion protein of Peste des petits ruminants virus and hemagglutination protein of Rinderpest virus and immunogenicity of the displayed proteins in mouse model. Virology. 2003;317:36-49 pubmed
    ..The antigenic epitopes of the recombinant proteins were properly displayed and the recombinant virus particles induced immune response in mice against PPRV or RPV. ..
  26. Abubakar M, Jamal S, Arshed M, Hussain M, Ali Q. Peste des petits ruminants virus (PPRV) infection; its association with species, seasonal variations and geography. Trop Anim Health Prod. 2009;41:1197-202 pubmed publisher
    ..The study also indicated the scenario of antibodies circulation in the population and proving that PPR is now becoming endemic and is one of the major emerging TAD in Pakistan...
  27. Minet C, Yami M, Egzabhier B, Gil P, Tangy F, Br mont M, et al. Sequence analysis of the large (L) polymerase gene and trailer of the peste des petits ruminants virus vaccine strain Nigeria 75/1: expression and use of the L protein in reverse genetics. Virus Res. 2009;145:9-17 pubmed publisher
    The large (L) polymerase gene and the 5'-terminal UTR of the genome of peste des petits ruminants virus (PPRV), vaccine strain Nigeria 75/1, were cloned and sequenced...
  28. Anderson J, McKay J. The detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes. Epidemiol Infect. 1994;112:225-31 pubmed
  29. Singh R, Sreenivasa B, Dhar P, Shah L, Bandyopadhyay S. Development of a monoclonal antibody based competitive-ELISA for detection and titration of antibodies to peste des petits ruminants (PPR) virus. Vet Microbiol. 2004;98:3-15 pubmed
    ..Findings suggest that the c-ELISA test developed can easily replace VNT for sero-surveillance, sero-monitoring, diagnosis from paired sera samples and end-point titration of PPR virus antibodies...
  30. Balamurugan V, Sen A, Saravanan P, Rasool T, Yadav M, Bandyopadhyay S, et al. Development and characterization of a stable vero cell line constitutively expressing Peste des petits ruminants virus (PPRV) hemagglutinin protein and its potential use as antigen in enzyme-linked immunosorbent assay for serosurveillance of PPRV. Clin Vaccine Immunol. 2006;13:1367-72 pubmed
    We developed and characterized a stable Vero cell line constitutively expressing Peste des petits ruminants virus (PPRV) hemagglutinin (H) protein and assessed its potential use as diagnostic antigen in enzyme-linked immunosorbent assay (..
  31. Parida S, Mahapatra M, Hawes P, Baron M, Monaghan P, Barrett T. Importance of the extracellular and cytoplasmic/transmembrane domains of the haemagglutinin protein of rinderpest virus for recovery of viable virus from cDNA copies. Virus Res. 2006;117:273-82 pubmed
    ..Both versions of the H protein and also the F protein were found to be incorporated into the envelope of the budded virions. ..
  32. Mahapatra M, Parida S, Egziabher B, Diallo A, Barrett T. Sequence analysis of the phosphoprotein gene of peste des petits ruminants (PPR) virus: editing of the gene transcript. Virus Res. 2003;96:85-98 pubmed
    ..The P protein was found to be the most poorly conserved of the morbillivirus proteins, the amino acid identity ranging from 54% in case of Canine distemper virus (CDV) to 60% in the case of the Dolphin morbillivirus (DMV). ..
  33. Kul O, Kabakci N, Atmaca H, Ozkul A. Natural peste des petits ruminants virus infection: novel pathologic findings resembling other morbillivirus infections. Vet Pathol. 2007;44:479-86 pubmed
    ..study describes pathologic and virologic findings in 15 sheep and 6 goats that died of natural peste des petits ruminants virus infection in Turkey...
  34. Logan N, McMonagle E, Drew A, Takahashi E, McDonald M, Baron M, et al. Efficient generation of vesicular stomatitis virus (VSV)-pseudotypes bearing morbilliviral glycoproteins and their use in quantifying virus neutralising antibodies. Vaccine. 2016;34:814-22 pubmed publisher
    ..Using this technique, we demonstrate cross neutralisation between CDV and peste des petits ruminants virus (PPRV)...
  35. Wu X, Liu F, Li L, Zou Y, Liu S, Wang Z. Major mutation events in structural genes of peste des petits ruminants virus through serial passages in vitro. Virus Genes. 2016;52:422-7 pubmed publisher
    Peste des petits ruminants (PPR) is an highly contagious disease of small ruminants, and caused by peste des petits ruminants virus (PPRV), a member of the genus Morbillivirus in the family Paramyxoviridae...
  36. Sujatha K, Shanthi G, Selvam N, Manoharan S, Perumal P, Rajendran M. Synthesis and antiviral activity of 4,4'-(arylmethylene)bis(1H-pyrazol-5-ols) against peste des petits ruminant virus (PPRV). Bioorg Med Chem Lett. 2009;19:4501-3 pubmed publisher
    ..Compound 3i emerged as the most interesting compound in this series exhibiting excellent antiviral activity against PPRV and found to be more potent than the standard drug ribavirin used...
  37. Liu F, Wu X, Li L, Zou Y, Liu S, Wang Z. Evolutionary characteristics of morbilliviruses during serial passages in vitro: Gradual attenuation of virus virulence. Comp Immunol Microbiol Infect Dis. 2016;47:7-18 pubmed publisher
  38. Choi K, Nah J, Choi C, Ko Y, Sohn H, Libeau G, et al. Monoclonal antibody-based competitive ELISA for simultaneous detection of rinderpest virus and peste des petits ruminants virus antibodies. Vet Microbiol. 2003;96:1-16 pubmed
    ..monoclonal antibody (P-13A9) was developed for simultaneous detection of rinderpest virus (RPV) and peste des petits ruminants virus (PPRV) antibodies and its diagnostic performance was evaluated...
  39. Chaudhary S, Pandey K, Singh R, Verma P, Gupta P. A vero cell derived combined vaccine against sheep pox and Peste des Petits ruminants for sheep. Vaccine. 2009;27:2548-53 pubmed publisher
    ..vaccine consisting of 10(3)TCID(50) each of sheep pox virus (SPV) Romanian Fanar (RF) strain and Peste des Petits ruminants virus (PPRV-Sungri/96 strain) were monitored for clinical and serological responses for a period of four ..
  40. He Y, Zhang Q, Fu M, Xu X. Development of multiplex PCR for simultaneous detection and differentiation of six DNA and RNA viruses from clinical samples of sheep and goats. J Virol Methods. 2017;243:44-49 pubmed publisher
    ..viruses and three RNA viruses, including foot and mouth disease virus (FMDV), Bluetongue virus (BTV), peste des petits ruminants virus (PPRV), sheeppox virus (SPPV), goatpox virus (GTPV) and orf virus (ORFV) were used for testing ..
  41. Ishag O, Saeed I, Ali Y. Peste des petits ruminants outbreaks in White Nile State, Sudan. Onderstepoort J Vet Res. 2015;82:E1-4 pubmed publisher
    ..b>Peste des petits ruminants virus was confirmed in tissues, nasal swabs and blood samples by immunocapture enzyme-linked immunosorbent ..
  42. Yu R, Zhu R, Gao W, Zhang M, Dong S, Chen B, et al. Fine mapping and conservation analysis of linear B-cell epitopes of peste des petits ruminants virus hemagglutinin protein. Vet Microbiol. 2017;208:110-117 pubmed publisher
    Hemagglutinin protein (H), one of the two glycoproteins of peste des petits ruminants virus (PPRV), binds to its receptor on the host cell and acts as a major antigen that induces and confers highly protective immunity in the host...
  43. Fakri F, Elhajjam A, Bamouh Z, Jazouli M, Boumart Z, Tadlaoui K, et al. Susceptibility of Moroccan sheep and goat breeds to peste des petits ruminants virus. Acta Vet Scand. 2017;59:56 pubmed publisher
    ..It is recommended that effective surveillance should focus on susceptible breeds complemented with serological surveillance of the sheep population. ..
  44. Hosamani M, Singh S, Mondal B, Sen A, Bhanuprakash V, Bandyopadhyay S, et al. A bivalent vaccine against goat pox and Peste des Petits ruminants induces protective immune response in goats. Vaccine. 2006;24:6058-64 pubmed
    Safety and immunogenicity of an experimental combined vaccine comprising attenuated strains of Peste des Petits ruminants virus (PPRV) and goat poxvirus (GTPV) was evaluated in goats...
  45. Fakri F, Embarki T, Parida S, Bamouh Z, Jazouli M, Mahapatra M, et al. Re-emergence of Peste des Petits Ruminants virus in 2015 in Morocco: Molecular characterization and experimental infection in Alpine goats. Vet Microbiol. 2016;197:137-141 pubmed publisher
    ..Therefore this study confirms a new incursion of PPR virus in Morocco during 2015 and highlights the urgency of implementation of a common control strategy to combat PPR in Maghreb region in North Africa. ..
  46. Fakri F, Elarkam A, Daouam S, Tadlaoui K, Fassi Fihri O, Richardson C, et al. VeroNectin-4 is a highly sensitive cell line that can be used for the isolation and titration of Peste des Petits Ruminants virus. J Virol Methods. 2016;228:135-9 pubmed publisher
    b>Peste des Petits Ruminants virus (PPRV) is a member of the Morbillivirus subgroup of the family Paramyxoviridae, and is one of the most contagious diseases of small ruminants throughout Africa and the rest of the world...
  47. Kerur N, Jhala M, Joshi C. Genetic characterization of Indian peste des petits ruminants virus (PPRV) by sequencing and phylogenetic analysis of fusion protein and nucleoprotein gene segments. Res Vet Sci. 2008;85:176-83 pubmed
    ..Thus, classification of PPRV into lineages based on the N gene sequences appeared to yield better picture of molecular epidemiology for PPRV. ..
  48. Kumar A, Yogisharadhya R, Venkatesan G, Bhanuprakash V, Shivachandra S. Immunogenicity and protective efficacy of recombinant major envelope protein (rH3L) of buffalopox virus in animal models. Antiviral Res. 2016;126:108-16 pubmed publisher
    ..sheeppox virus (SPPV), goatpox virus (GTPV), orf virus (ORFV), foot- and- mouth disease virus (FMDV), peste des petits ruminants virus (PPRV) and bluetongue virus (BTV) during the course of study...
  49. Couacy Hymann E, Bodjo C, Danho T, Libeau G, Diallo A. Evaluation of the virulence of some strains of peste-des-petits-ruminants virus (PPRV) in experimentally infected West African dwarf goats. Vet J. 2007;173:178-83 pubmed
    ..The viruses studied contained examples of PPRV from specific lineage groups based on their nucleoprotein PPRV gene. This experiment indicated that virulence characteristics might be a useful marker to help classify PPRV isolates. ..
  50. Servan de Almeida R, Keita D, Libeau G, Albina E. Control of ruminant morbillivirus replication by small interfering RNA. J Gen Virol. 2007;88:2307-11 pubmed
    ..The findings of this work highlight the potential for siRNA molecules to be developed as therapeutic agents for the treatment of PPRV and RPV infections...
  51. Holzer B, Taylor G, Rajko Nenow P, Hodgson S, Okoth E, Herbert R, et al. Determination of the minimum fully protective dose of adenovirus-based DIVA vaccine against peste des petits ruminants virus challenge in East African goats. Vet Res. 2016;47:20 pubmed publisher
    b>Peste des petits ruminants virus (PPRV) causes an economically important disease of sheep and goats, primarily in developing countries. It is becoming the object of intensive international control efforts...
  52. Li J, Li W, Mao L, Hao F, Yang L, Zhang W, et al. Rapid detection of novel caprine parainfluenza virus type 3 (CPIV3) using a TaqMan-based RT-qPCR. J Virol Methods. 2016;236:126-131 pubmed publisher
    ..6% and a R(2) value of 0.997. There were no cross-reaction observed using this technique against peste des petits ruminants virus (PPRV), border disease virus (BDV), bluetongue virus (BTV) and bovine viral diarrhea virus (BVDV)...
  53. Yang B, Qi X, Chen Z, Chen S, Xue Q, Jia P, et al. Binding and entry of peste des petits ruminants virus into caprine endometrial epithelial cells profoundly affect early cellular gene expression. Vet Res. 2018;49:8 pubmed publisher
    b>Peste des petits ruminants virus (PPRV), the etiological agent of peste des petits ruminants (PPR), causes an acute or subacute disease in small ruminants...
  54. Muthuchelvan D, Sanyal A, Singh R, Hemadri D, Sen A, Sreenivasa B, et al. Comparative sequence analysis of the large polymerase protein (L) gene of peste-des-petits ruminants (PPR) vaccine virus of Indian origin. Arch Virol. 2005;150:2467-81 pubmed
    ..To the best of our knowledge this is the first report describing the polymerase gene sequence of PPRV Indian isolate...
  55. Liu F, Wu X, Zou Y, Li L, Liu S, Chi T, et al. Small interfering RNAs targeting peste des petits ruminants virus M mRNA increase virus-mediated fusogenicity and inhibit viral replication in vitro. Antiviral Res. 2015;123:22-6 pubmed publisher
    Peste des petits ruminants (PPR), caused by peste des petits ruminants virus (PPRV), is an acute or subacute, highly contagious and economically important disease of small ruminants...
  56. George A, Dhar P, Sreenivasa B, Singh R, Bandyopadhyay S. The M and N genes-based simplex and multiplex PCRs are better than the F or H gene-based simplex PCR for Peste-des-petits-ruminants virus. Acta Virol. 2006;50:217-22 pubmed
    ..The multiplex PCR was as sensitive as the M gene PCR, but it had the advantage of differentiating PPRV from Rinderpest virus (RPV). ..
  57. Al Naeem A, Abu Elzein E. In situ detection of PPR virus antigen in skin papules around the mouth of sheep experimentally infected with PPR virus. Trop Anim Health Prod. 2008;40:239-41 pubmed
  58. Silva A, Delgado I, Sousa M, Carrondo M, Alves P. Scalable culture systems using different cell lines for the production of Peste des Petits ruminants vaccine. Vaccine. 2008;26:3305-11 pubmed publisher
  59. Bao J, Zhao W, Wang Z, Li L, Wu G, Wu X, et al. [Sequence analysis of the matrix protein and fusion protein genes of a field peste des petits ruminants virus strain from Tibet, China]. Bing Du Xue Bao. 2010;26:305-14 pubmed
    The nucleotide sequences of M and F genes from a field strain of peste des petits ruminants virus (PPRV) ("China/Tib/Gej/07-30") was firstly determined...
  60. Forsyth M, Parida S, Alexandersen S, Belsham G, Barrett T. Rinderpest virus lineage differentiation using RT-PCR and SNAP-ELISA. J Virol Methods. 2003;107:29-36 pubmed
    ..and differentiates Rinderpest virus (RPV) from the other closely related morbillivirus of ruminants, Peste des petits Ruminants virus (PPRV)...
  61. Singh R, Sreenivasa B, Dhar P, Bandyopadhyay S. A sandwich-ELISA for the diagnosis of Peste des petits ruminants (PPR) infection in small ruminants using anti-nucleocapsid protein monoclonal antibody. Arch Virol. 2004;149:2155-70 pubmed
    ..PPR outbreaks from various parts of India have been confirmed using the test. Findings suggested that the newly developed ELISA is suitable for PPR diagnosis under field conditions...
  62. de Swart R, Harder T, Ross P, Vos H, Osterhaus A. Morbilliviruses and morbillivirus diseases of marine mammals. Infect Agents Dis. 1995;4:125-30 pubmed
    ..In addition, the possible contributory role of environmental contaminant-related immunosuppression in the severity and extent of the different disease outbreaks is discussed. ..
  63. Michaud V, Gil P, Kwiatek O, Prome S, Dixon L, Romero L, et al. Long-term storage at tropical temperature of dried-blood filter papers for detection and genotyping of RNA and DNA viruses by direct PCR. J Virol Methods. 2007;146:257-65 pubmed
    ..PCR products obtained from the filter papers were sequenced and phylogenetic analysis carried out. The results were consistent with published sequences, demonstrating that this method can be used for virus genotyping. ..
  64. Saravanan P, Sen A, Balamurugan V, Bandyopadhyay S, Singh R. Rapid quality control of a live attenuated Peste des petits ruminants (PPR) vaccine by monoclonal antibody based sandwich ELISA. Biologicals. 2008;36:1-6 pubmed
    ..It is concluded that S-ELISA could be a preliminary tool useful for the quality control of PPR vaccine as it is rapid and easy to perform when compared to virus titration...
  65. Parida S, Mahapatra M, Kumar S, Das S, Baron M, Anderson J, et al. Rescue of a chimeric rinderpest virus with the nucleocapsid protein derived from peste-des-petits-ruminants virus: use as a marker vaccine. J Gen Virol. 2007;88:2019-27 pubmed
    ..The possibility of using this virus as a marker vaccine in association with a new diagnostic ELISA in the rinderpest eradication programme is discussed...
  66. Waret Szkuta A, Roger F, Chavernac D, Yigezu L, Libeau G, Pfeiffer D, et al. Peste des petits ruminants (PPR) in Ethiopia: analysis of a national serological survey. BMC Vet Res. 2008;4:34 pubmed publisher
    ..Our estimates of intracluster correlation may prove useful in the design of serosurveys in other countries where PPR is of importance. ..
  67. Couacy Hymann E, Bodjo S, Danho T, Koffi M, Libeau G, Diallo A. Early detection of viral excretion from experimentally infected goats with peste-des-petits ruminants virus. Prev Vet Med. 2007;78:85-8 pubmed
    ..This experiment indicates that incubatory carriers therefore might play a role in the transmission of PPRV among small ruminants. ..
  68. Taylor W, Diallo A, Gopalakrishna S, Sreeramalu P, Wilsmore A, Nanda Y, et al. Peste des petits ruminants has been widely present in southern India since, if not before, the late 1980s. Prev Vet Med. 2002;52:305-12 pubmed
    ..PPR outbreaks have been frequent in recent years. Further, we suggest that PPR is not a recent invader of India...
  69. Toplu N. Characteristic and non-characteristic pathological findings in peste des petits ruminants (PPR) of sheep in the Ege district of Turkey. J Comp Pathol. 2004;131:135-41 pubmed
    ..Immunohistochemically, viral antigen was strongly labelled in the lung, oral tissues and small intestine...
  70. Rajak K, Sreenivasa B, Hosamani M, Singh R, Singh S, Singh R, et al. Experimental studies on immunosuppressive effects of peste des petits ruminants (PPR) virus in goats. Comp Immunol Microbiol Infect Dis. 2005;28:287-96 pubmed
  71. Muthuchelvan D, Sanyal A, Sarkar J, Sreenivasa B, Bandyopadhyay S. Comparative nucleotide sequence analysis of the phosphoprotein gene of peste des petits ruminants vaccine virus of Indian origin. Res Vet Sci. 2006;81:158-64 pubmed
    ..This will be the third sequence for the P gene of PPRV since that of the vaccine strain and a wild-type Turkish isolate has been published already. ..
  72. Khan H, Siddique M, Arshad M, Abubakar M, Akhtar M, Arshad M, et al. Post-vaccination antibodies profile against Peste des petits ruminants (PPR) virus in sheep and goats of Punjab, Pakistan. Trop Anim Health Prod. 2009;41:427-30 pubmed publisher
    ..Mean PI values in sheep at 10, 30 and 45 days post-vaccination were recorded as 37, 65 and 91 respectively, whereas in goats these values were 43, 78 and 86 respectively. ..
  73. raj G, Kumar A, Shaila M, Nachimuthu K, Palaniswami K. Molecular epidemiology of peste des petits ruminants viruses from southern India. Vet Rec. 2003;152:264-6 pubmed
  74. Sreenivasa B, Singh R, Mondal B, Dhar P, Bandyopadhyay S. Marmoset B95a cells: a sensitive system for cultivation of Peste des petits ruminants (PPR) virus. Vet Res Commun. 2006;30:103-8 pubmed
  75. Hegde R, Gomes A, Muniyellappa H, Byregowda S, Giridhar P, Renukaprasad C. A short note on peste des petits ruminants in Karnataka, India. Rev Sci Tech. 2009;28:1031-5 pubmed
    ..The disease data documented in this study provide information about the endemicity of the disease that can help to formulate an effective strategy for a PPR-control programme in the state. ..