avian myeloblastosis virus

Summary

Summary: A species of ALPHARETROVIRUS causing anemia in fowl.

Top Publications

  1. Brendeford E, Myrset A, Hegvold A, Lundin M, Gabrielsen O. Oncogenic point mutations induce altered conformation, redox sensitivity, and DNA binding in the minimal DNA binding domain of avian myeloblastosis virus v-Myb. J Biol Chem. 1997;272:4436-43 pubmed
    ..Activated oncogenic forms of Myb are encoded by the avian retroviruses, avian myeloblastosis virus (AMV) and E26. AMV v-Myb encodes a truncated protein with 11 point mutations relative to c-Myb...
  2. Perbal B. Pathogenic potential of myeloblastosis-associated viruses. Infect Agents Dis. 1995;4:212-27 pubmed
  3. Schneider D, Feigon J, Hostomsky Z, Gold L. High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus. Biochemistry. 1995;34:9599-610 pubmed
    ..These ssDNA molecules may be useful as inhibitors or as models for the design of small molecule inhibitors of HIV-1 RT in vivo...
  4. Oehler T, Arnold H, Biedenkapp H, Klempnauer K. Characterization of the v-myb DNA binding domain. Nucleic Acids Res. 1990;18:1703-10 pubmed
    ..Our results support the view that specific sequence-recognition, mediated by the conserved myb repeats, is a general feature of myb-related proteins...
  5. Cai H, Bloom L, Eritja R, Goodman M. Kinetics of deoxyribonucleotide insertion and extension at abasic template lesions in different sequence contexts using HIV-1 reverse transcriptase. J Biol Chem. 1993;268:23567-72 pubmed
    ..A striking result was that while primers were extended past an abasic lesion by HIV-1 RT in both direct and misalignment modes, avian myeloblastosis virus RT failed to catalyze significant extension by either mode.
  6. Yu H, Goodman M. Comparison of HIV-1 and avian myeloblastosis virus reverse transcriptase fidelity on RNA and DNA templates. J Biol Chem. 1992;267:10888-96 pubmed
    A comparison of the fidelity of reverse transcriptases (RT) from human immunodeficiency virus (HIV-1) and avian myeloblastosis virus (AMV) is made using RNA and DNA primer-template molecules in vitro...
  7. Fuentes G, Fay P, Bambara R. Relationship between plus strand DNA synthesis removal of downstream segments of RNA by human immunodeficiency virus, murine leukemia virus and avian myeloblastoma virus reverse transcriptases. Nucleic Acids Res. 1996;24:1719-26 pubmed
    ..This suggests that degradation of downstream pieces of RNA is not absolutely required before synthesis of the plus strand DNA. The implications of these findings for viral replication are discussed...
  8. Tozser J, Bagossi P, Weber I, Copeland T, Oroszlan S. Comparative studies on the substrate specificity of avian myeloblastosis virus proteinase and lentiviral proteinases. J Biol Chem. 1996;271:6781-8 pubmed
    ..Here a similar approach is used to characterize the specificity of avian myeloblastosis virus (AMV) PR and to compare it with those of the previously characterized lentiviral PRs...
  9. Burk O, Mink S, Ringwald M, Klempnauer K. Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors. EMBO J. 1993;12:2027-38 pubmed
    ..Our results suggest a role for C/EBP beta, and possibly for other C/EBP transcription factors, in v-myb function and in myeloid-specific gene activation...

More Information

Publications98

  1. DeStefano J, Mallaber L, Fay P, Bambara R. Quantitative analysis of RNA cleavage during RNA-directed DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases. Nucleic Acids Res. 1994;22:3793-800 pubmed
    ..extent of RNA cleavage carried out during DNA synthesis by either human immunodeficiency virus (HIV) or avian myeloblastosis virus (AMV) reverse transcriptases (RTs)...
  2. Introna M, Golay J, Frampton J, Nakano T, Ness S, Graf T. Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene. Cell. 1990;63:1289-97 pubmed
    ..These results indicate that different forms of v-myb impose alternate phenotypes of differentiation on transformed myeloid cells, probably by regulating unique sets of differentiation-specific genes...
  3. Ness S, Marknell A, Graf T. The v-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. Cell. 1989;59:1115-25 pubmed
    ..We conclude that mim-1 is a cellular gene that is directly regulated by the product of the v-myb oncogene...
  4. Joliot V, Boroughs K, Lasserre F, Crochet J, Dambrine G, Smith R, et al. Pathogenic potential of myeloblastosis-associated virus: implication of env proteins for osteopetrosis induction. Virology. 1993;195:812-9 pubmed
    ..These results, together with sequence comparisons between the MAV strains examined, suggest that subtle changes in the primary structure of the TM env protein's extracellular domain are likely to affect the tumorigenic potential of MAV...
  5. Soret J, Dambrine G, Perbal B. Induction of nephroblastoma by myeloblastosis-associated virus type 1: state of proviral DNAs in tumor cells. J Virol. 1989;63:1803-7 pubmed
    ..Rearrangements occur preferentially in the gag-pol region of the MAV1 proviral genome, and similar rearrangements can be detected in well-developed independent tumors...
  6. Burk O, Worpenberg S, Haenig B, Klempnauer K. tom-1, a novel v-Myb target gene expressed in AMV- and E26-transformed myelomonocytic cells. EMBO J. 1997;16:1371-80 pubmed
    ..Together with previous work our results suggest that C/EBP may be a general cooperation partner for v-Myb in myelomonocytic cells...
  7. Lipsick J, Wang D. Transformation by v-Myb. Oncogene. 1999;18:3047-55 pubmed
    The v-myb oncogene of the avian myeloblastosis virus (AMV) is unique among known oncogenes in that it causes only acute leukemia in animals and transforms only hematopoietic cells in culture...
  8. Yasukawa K, Nemoto D, Inouye K. Comparison of the thermal stabilities of reverse transcriptases from avian myeloblastosis virus and Moloney murine leukaemia virus. J Biochem. 2008;143:261-8 pubmed
    Reverse transcriptases (RTs) from avian myeloblastosis virus (AMV) and Moloney murine leukaemia virus (MMLV) have been most extensively used as a tool for conversion of RNA to DNA...
  9. Roberts J, Preston B, Johnston L, Soni A, Loeb L, Kunkel T. Fidelity of two retroviral reverse transcriptases during DNA-dependent DNA synthesis in vitro. Mol Cell Biol. 1989;9:469-76 pubmed
    We determined the fidelity of avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases (RTs) during DNA synthesis in vitro using the M13mp2 lacZ alpha gene as a mutational target...
  10. Klempnauer K, Sippel A. The highly conserved amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 1987;6:2719-25 pubmed
    ..This region has been highly conserved between myb genes of different species. Our results are therefore consistent with the hypothesis that DNA-binding is an important aspect of myb protein function...
  11. Shimomaye E, Salvato M. Use of avian myeloblastosis virus reverse transcriptase at high temperature for sequence analysis of highly structured RNA. Gene Anal Tech. 1989;6:25-8 pubmed
    b>Avian myeloblastosis virus reverse transcriptase (AMV RT) is routinely used in the sequence analysis of RNA and DNA templates...
  12. Korb J, Stokrova J, Riman J, Sulová A. Avian myeloblastosis virus core-bound 7 S DNA, highly bent minute structures with sequence-directed curvature. Acta Virol. 1993;37:343-59 pubmed
    Structural properties and length distribution profile of 7 S avian myeloblastosis virus (AMV) DNA were studied by means of electron microscopy using two different techniques...
  13. Zavala G, Cheng S, Barbosa T. Natural infection and transmission of a retrovirus closely related to myeloblastosis-associated virus type 1 in egg-type chickens. Avian Dis. 2012;56:7-14 pubmed
  14. Ben Artzi H, Zeelon E, Amit B, Wortzel A, Gorecki M, Panet A. RNase H activity of reverse transcriptases on substrates derived from the 5' end of retroviral genome. J Biol Chem. 1993;268:16465-71 pubmed
    ..leukemia virus (MMuLV) genomes were used to study the specificity of the RNase H activities of HIV, AMV (avian myeloblastosis virus), and MMuLV reverse transcriptases...
  15. Gelfand C, Wang Q, Randall S, Jentoft J. Interactions of avian myeloblastosis virus nucleocapsid protein with nucleic acids. J Biol Chem. 1993;268:18450-6 pubmed
    ..We have used the anisotropy of the intrinsic fluorescence of NC from avian myeloblastosis virus to quantify its binding to a variety of nucleic acids...
  16. Cameron C, Grinde B, Jentoft J, Leis J, Weber I, Copeland T, et al. Mechanism of inhibition of the retroviral protease by a Rous sarcoma virus peptide substrate representing the cleavage site between the gag p2 and p10 proteins. J Biol Chem. 1992;267:23735-41 pubmed
    The activity of the avian myeloblastosis virus (AMV) or the human immunodeficiency virus type 1 (HIV-1) protease on peptide substrates which represent cleavage sites found in the gag and gag-pol polyproteins of Rous sarcoma virus (RSV) ..
  17. Perbal B. Contribution of MAV-1-induced nephroblastoma to the study of genes involved in human Wilms' tumor development. Crit Rev Oncog. 1994;5:589-613 pubmed
    ..The recent data that are discussed in this review strongly suggest that the nov protein might play a critical role in normal and pathological nephrogenesis. ..
  18. Pecenka V, Dvorak M, Travnicek M. Avian nephroblastomas induced by a retrovirus (MAV-2) lacking oncogene. I. Construction of MAV-1 and MAV-2 proviral restriction maps and preparation of specific proviral molecular subclones. Folia Biol (Praha). 1988;34:129-46 pubmed
    ..Thus tools for analysis of integrated MAV-2 proviruses in nephroblastomas induced by this virus were formed. ..
  19. Joliot V, Martinerie C, Dambrine G, Plassiart G, Brisac M, Crochet J, et al. Proviral rearrangements and overexpression of a new cellular gene (nov) in myeloblastosis-associated virus type 1-induced nephroblastomas. Mol Cell Biol. 1992;12:10-21 pubmed
    ..We also showed that the expression of an amino-terminal-truncated nov product in chicken embryo fibroblasts was sufficient to induce their transformation. ..
  20. Juca M, Aoyama H. Effect of dimethyl sulfoxide on reverse transcriptase activity. Braz J Med Biol Res. 1995;28:285-90 pubmed
    At low concentrations, dimethyl sulfoxide (DMSO) stimulated the avian myeloblastosis virus reverse transcriptase activity...
  21. Kotler M, Katz R, Danho W, Leis J, Skalka A. Synthetic peptides as substrates and inhibitors of a retroviral protease. Proc Natl Acad Sci U S A. 1988;85:4185-9 pubmed
    ..Thus, small model substrates may be used to explore both the binding and catalytic properties of these important proteases...
  22. Groppe J, Morse D. Isolation of full-length RNA templates for reverse transcription from tissues rich in RNase and proteoglycans. Anal Biochem. 1993;210:337-43 pubmed
    ..This cold two-step method should prove useful for providing full-length RNA templates relatively free of polysaccharide, a common contaminant of RNA preparations, from both plant and animal tissues. ..
  23. Dietrich C, Al Abdallah Q, Lintl L, Pietruszka A, Maiss E. A chimeric plum pox virus shows reduced spread and cannot compete with its parental wild-type viruses in a mixed infection. J Gen Virol. 2007;88:2846-51 pubmed
    ..These data suggest that, in PPV infections, symptom severity and competitiveness are independent aspects and that spatial separation may contribute to the displacement of a recombinant virus. ..
  24. Schirm S, Moscovici G, Bishop J. A temperature-sensitive phenotype of avian myeloblastosis virus: determinants that influence the production of viral mRNAs. J Virol. 1990;64:767-73 pubmed
    The oncogene v-myb of avian myeloblastosis virus is expressed from an mRNA that arises by splicing of the viral genome...
  25. Cummins T, Smith R. Association of persistent synthesis of viral DNA with macrophage accessory cell dysfunction induced by avian retrovirus myeloblastosis-associated virus of subgroup B inducing osteopetrosis in chickens. Cancer Res. 1987;47:6033-9 pubmed
    ..Therefore, it was speculated that the persistent synthesis of retrovirus DNA might be involved in the inability of infected macrophages to function as accessory cells. ..
  26. Chesters P, Howes K, Petherbridge L, Evans S, Payne L, Venugopal K. The viral envelope is a major determinant for the induction of lymphoid and myeloid tumours by avian leukosis virus subgroups A and J, respectively. J Gen Virol. 2002;83:2553-61 pubmed
    ..Induction of both LL and ML by the two chimeric viruses occurred through the activation of c-myc, while the EB tumours were induced by activation of the c-erbB oncogene...
  27. Vranovský K, Bartunek P, Cermáková V, Forstova J, Dvorak M, Doskocil J. Production of v-Myb and c-Myb in insect cells infected with recombinant baculoviruses. Gene. 1992;117:233-5 pubmed
    ..The system provides a convenient source of relatively large amounts of v-Myb or c-Myb for in vitro binding studies. ..
  28. Bagossi P, Sperka T, Fehér A, Kadas J, Zahuczky G, Miklossy G, et al. Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites. J Virol. 2005;79:4213-8 pubmed
    ..Specificities at this position were compared for HIV-1, HIV-2, equine infectious anemia virus, avian myeloblastosis virus, Mason-Pfizer monkey virus, mouse mammary tumor virus, Moloney murine leukemia virus, human T-cell ..
  29. Leis J, Phillips N, Fu X, Tuazon P, Traugh J. Phosphorylation of avian retrovirus matrix protein by Ca2+/phospholipid-dependent protein kinase. Eur J Biochem. 1989;179:415-22 pubmed
    The matrix protein from avian myeloblastosis virus and the Rous sarcoma virus, Prague C strain, is a phosphoprotein. A comparison of the amino acid sequences shows these phosphoproteins are very similar...
  30. Vora A, Grandgenett D. DNase protection analysis of retrovirus integrase at the viral DNA ends for full-site integration in vitro. J Virol. 2001;75:3556-67 pubmed
    ..Molecular insights into the organization of avian myeloblastosis virus IN at the viral DNA ends were gained by reconstituting nucleoprotein complexes possessing intasome ..
  31. Crews S, Barth R, Hood L, Prehn J, Calame K. Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. Science. 1982;218:1319-21 pubmed
    ..The translocated c-myc sequence is not the same oncogene detected in urine plasmacytomas by the NIH-3T3 cell transformation assay. ..
  32. Bading H. Determination of the molecular weight of DNA-bound protein(s) responsible for gel electrophoretic mobility shift of linear DNA fragments examplified with purified viral myb protein. Nucleic Acids Res. 1988;16:5241-8 pubmed
    ..As an example this calculation was used in order to analyse DNA-binding of the isolated viral myb protein. It could be demonstrated that the viral myb protein binds to DNA as a monomer and as a dimer. ..
  33. Minth C, Andrews P, Dixon J. Characterization, sequence, and expression of the cloned human neuropeptide Y gene. J Biol Chem. 1986;261:11974-9 pubmed
    ..by primer extension analysis using a primer derived from a human cDNA, pheochromocytoma RNA and avian myeloblastosis virus reverse transcriptase...
  34. Ibanez C, Lipsick J. Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation. J Virol. 1988;62:1981-8 pubmed
    The v-myb oncogene of avian myeloblastosis virus causes acute myelomonocytic leukemia in vivo and transforms only myeloid cells in vitro. Its product, p48v-myb, is a nuclear protein of unknown function...
  35. Rosson D, Reddy E. Nucleotide sequence of chicken c-myb complementary DNA and implications for myb oncogene activation. Nature. 1986;319:604-6 pubmed
    b>Avian myeloblastosis virus (AMV), like other acute transforming viruses, arose by recombination between its helper virus and host cellular sequences...
  36. Semar M, Anke H, Arendholz W, Velten R, Steglich W. Lachnellins A, B, C, D, and naphthalene-1,3,8-triol, biologically active compounds from a Lachnellula species (ascomycetes). Z Naturforsch C. 1996;51:500-12 pubmed
    ..In addition, rac-scytalone (9), (+)-trans-3,4-dihydro-3,4,8-trihydroxy-1 (2H)-naphthalenone (10), 2,5-dihydroxytoluene (11), and (R)-(-)-5-methylmellein (12) were obtained from the same source and biologically characterized. ..
  37. Lorsch J, Bartel D, Szostak J. Reverse transcriptase reads through a 2'-5'linkage and a 2'-thiophosphate in a template. Nucleic Acids Res. 1995;23:2811-4 pubmed
    b>Avian myeloblastosis virus and Maloney murine leukemia virus RNase H-reverse transcriptases pause when they encounter a 2'-5' linkage or a 2'-thiophosphate in their template RNAs, but eventually read through these backbone modifications...
  38. Klempnauer K, Gonda T, Bishop J. Nucleotide sequence of the retroviral leukemia gene v-myb and its cellular progenitor c-myb: the architecture of a transduced oncogene. Cell. 1982;31:453-63 pubmed
    The oncogene (v-myb) of avian myeloblastosis virus and a large portion of its cellular homolog (c-myb) have been molecularly cloned and sequenced. The portion of c-myb we analyzed contains seven interspersed segments (or exons)...
  39. Hafuri Y, Takemori E, Oogose K, Inouye Y, Nakamura S, Kitahara Y, et al. Mechanism of inhibition of reverse transcriptase by quinone antibiotics. II. Dependence on putative quinone pocket on the enzyme molecule. J Antibiot (Tokyo). 1988;41:1471-8 pubmed
    Inhibition of avian myeloblastosis virus (AMV) reverse transcriptase by natural and synthetic quinones including antibiotics could be accounted for by an oxidation-reduction reaction...
  40. Alexandrova L, Skoblov A, Jasko M, Victorova L, Krayevsky A. 2'-Deoxynucleoside 5'-triphosphates modified at alpha-, beta- and gamma-phosphates as substrates for DNA polymerases. Nucleic Acids Res. 1998;26:778-86 pubmed
    ..HIV reverse transcriptase utilized these compounds 1 order of magnitude less efficiently than AMV reverse transcriptase; terminal deoxynucleotidyl transferase did not recognize them at all. ..
  41. Lomri A, Baron R. 1 alpha,25-dihydroxyvitamin D3 regulates the transcription of carbonic anhydrase II mRNA in avian myelomonocytes. Proc Natl Acad Sci U S A. 1992;89:4688-92 pubmed
    ..These results suggest that activation of the CAII gene occurs early in the differentiation events triggered by vitamin D3 in myelomonocytic cells. ..
  42. Martinez M, Sala M, Vartanian J, Wain Hobson S. Reverse transcriptase and substrate dependence of the RNA hypermutagenesis reaction. Nucleic Acids Res. 1995;23:2573-8 pubmed
    ..three reverse transcriptases (RTases) available, those of human immunodeficiency virus type 1 (HIV-1), avian myeloblastosis virus (AMV) and Moloney murine leukemia virus (MoMLV), the HIV-1 enzyme showed the greatest sensitivity to ..
  43. Garrido C, Leprince D, Lipsick J, Stehelin D, Gospodarowicz D, Saule S. Definition of functional domains in P135gag-myb-ets and p48v-myb proteins required to maintain the response of neuroretina cells to basic fibroblast growth factor. J Virol. 1992;66:160-6 pubmed
    ..The v-myb-containing avian myeloblastosis virus also induces the proliferation of infected CNR cells stimulated by bFGF...
  44. Ibanez C, Garcia A, Stober Grässer U, Lipsick J. DNA-binding activity associated with the v-myb oncogene product is not sufficient for transformation. J Virol. 1988;62:4398-402 pubmed
    The product of the v-myb oncogene of avian myeloblastosis virus is a nuclear protein with an associated DNA-binding activity...
  45. Secnik J, Gelfand C, Jentoft J. Retroviral nucleocapsid protein specifically recognizes the base and the ribose of mononucleotides and mononucleotide components. Biochemistry. 1992;31:2982-8 pubmed
    ..site and of the forces that drive its interaction with nucleic acids, the relative affinities of NC from avian myeloblastosis virus were determined for a series of mononucleotides and mononucleotide components using a competitive ..
  46. Chen H, McBroom D, Zhu Y, Gold L, North T. Inhibitory RNA ligand to reverse transcriptase from feline immunodeficiency virus. Biochemistry. 1996;35:6923-30 pubmed
    ..This ligand was specific for the FIV enzyme and did not inhibit other reverse transcriptases tested (avian myeloblastosis virus, Moloney murine leukemia virus, and human immunodeficiency virus type 1).
  47. Dhananjaya K, Antony A. Pharmacokinetics and chemotherapeutic efficacy of adriamycin encapsulated in immunoliposomes against avian myeloblastosis virus infection. J Virol Methods. 1988;19:121-9 pubmed
    Immunoliposomes were prepared using rabbit anti-AMV gp80 IgG for the targeted chemotherapy of avian myeloblastosis virus infection. Adriamycin was encapsulated into immunoliposomes and used for in vivo studies...
  48. Lautenberger J, Kan N, Court D, Pry T, Showalter S, Papas T. High-level expression of oncogenes in Escherichia coli. Gene Amplif Anal. 1983;3:147-74 pubmed
    ..sites allowed us to fuse the sequences from the avian myelocytomatosis virus (MC29) v-myc gene, the avian myeloblastosis virus (AMV) v-myb gene, and the Harvey murine sarcoma virus (Ha-MuSV) v-ras gene to the amino-terminal portion ..
  49. Riman J. Anatomy of the primase-alpha DNA polymerase reaction accomplished by nucleoprotein complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus core-bound DNA: influencing by carbonyldiphosphonate, mimosine and butylphenyl de. Acta Virol. 2001;45:109-24 pubmed
    ..reaction systems represented by special NP complexes harboring an extrachromosomal DNA identical with avian myeloblastosis virus (AMV) core-bound DNA (J. Riman, A. Sulová and K. Horská, Acta virol. 39, 149-159 (1995); J...
  50. Oyama F, Kikuchi R, Crouch R, Uchida T. Intrinsic properties of reverse transcriptase in reverse transcription. Associated RNase H is essentially regarded as an endonuclease. J Biol Chem. 1989;264:18808-17 pubmed
    ..With or without concomitant cDNA synthesis, the RNase H activity of avian myeloblastosis virus (AMV)-reverse transcriptase cleaved the substrate at a site which would leave a hybrid of between 7 and ..
  51. Erkel G, Anke T, Gimenez A, Steglich W. Antibiotics from basidiomycetes. XLI. Clavicoronic acid, a novel inhibitor of reverse transcriptases from Clavicorona pyxidata (Pers. ex Fr.) Doty. J Antibiot (Tokyo). 1992;45:29-37 pubmed
    ..Clavicoronic acid (1) is a noncompetitive inhibitor of avian myeloblastosis virus (Ki 130 microM) and Moloney murine leukemia virus (Ki 68 microM) reverse transcriptases...
  52. Fitzgerald M, Vora A, Zeh W, Grandgenett D. Concerted integration of viral DNA termini by purified avian myeloblastosis virus integrase. J Virol. 1992;66:6257-63 pubmed
  53. Fu S, Lipsick J. FAETL motif required for leukemic transformation by v-Myb. J Virol. 1996;70:5600-10 pubmed
    The nuclear protein v-Myb, encoded by the avian myeloblastosis virus (AMV), can induce acute monoblastic leukemia in vivo and transform chicken myelomonocytic cells in culture...
  54. Wilczek C, Chayka O, Plachetka A, Klempnauer K. Myb-induced chromatin remodeling at a dual enhancer/promoter element involves non-coding rna transcription and is disrupted by oncogenic mutations of v-myb. J Biol Chem. 2009;284:35314-24 pubmed publisher
    The oncogene v-myb of avian myeloblastosis virus (AMV) encodes a transcription factor (v-Myb) that transforms myelomonocytic cells by deregulating the expression of specific target genes...
  55. Wilson J, DeRiel J, Forget B, Marotta C, Weissman S. Nucleotide sequence of 3' untranslated portion of human alpha globin mRNA. Nucleic Acids Res. 1977;4:2353-68 pubmed
  56. Mroczkowska M, Kusmierek J. The effect of neighboring bases on miscoding properties of N2,3-ethenoguanine. Z Naturforsch C. 1993;48:63-7 pubmed
    ..These results suggest that mutagenic potential of epsilon G in vivo can depend on the nature of neighboring bases...
  57. Agnes F, Crance J, LeVeque F. Separate detection of the two complementary RNA strands of hepatitis A virus. J Virol Methods. 1994;49:323-30 pubmed
    ..This problem was overcome by the use of the thermostable rTth DNA polymerase that also has reverse transcriptase activity in the presence of Mn2+...
  58. Cameron C, Grinde B, Jacques P, Jentoft J, Leis J, Wlodawer A, et al. Comparison of the substrate-binding pockets of the Rous sarcoma virus and human immunodeficiency virus type 1 proteases. J Biol Chem. 1993;268:11711-20 pubmed
    A steady state kinetic analysis of the avian myeloblastosis virus/Rous sarcoma virus (AMV/RSV) and human immunodeficiency virus Type 1 (HIV-1) retroviral proteases (PRs) was carried out using a series of 40 peptide substrates that are ..
  59. Dhananjaya K, Antony A. Cytotoxic activity of daunomycin and adriamycin encapsulated in immunoliposomes against avian myeloblastosis virus-infected cells. J Virol Methods. 1988;19:131-40 pubmed
    Immunoliposomes were prepared using the antibody raised against the avian myeloblastosis virus envelope glycoprotein, gp80. Adriamycin was encapsulated into immunoliposomes...
  60. Luo G, Sharmeen L, Taylor J. Specificities involved in the initiation of retroviral plus-strand DNA. J Virol. 1990;64:592-7 pubmed
    ..acid sequences from the genome of Rous sarcoma virus along with three different sources of RNase H: avian myeloblastosis virus DNA polymerase, murine leukemia virus DNA polymerase, and the RNase H of Escherichia coli...
  61. Keith G, Heyman T. Heterogeneities in vertebrate tRNAs(Trp) avian retroviruses package only as a primer the tRNA(Trp) lacking modified m2G in position 7. Nucleic Acids Res. 1990;18:703-10 pubmed
    Bovine, rabbit and chicken tRNA(Trp) species and tRNA(Trp) packaged in avian myeloblastosis virus were separated and purified using two-dimensional gel electrophoresis and their primary structures were determined...
  62. Joliot V, Khelifi C, Wyers M, Dambrine G, Lasserre F, Lemercier P, et al. The noncoding and surface envelope coding sequences of myeloblastosis-associated virus are respectively responsible for nephroblastoma development and renal hyperplasia. J Virol. 1996;70:2576-80 pubmed
  63. Yasukawa K, Mizuno M, Inouye K. Characterization of Moloney murine leukaemia virus/avian myeloblastosis virus chimeric reverse transcriptases. J Biochem. 2009;145:315-24 pubmed publisher
    Reverse transcriptases (RTs) from Moloney murine leukaemia virus (MMLV) and avian myeloblastosis virus (AMV) contain all the fingers, palm, thumb, connection and RNase H domains...
  64. Bukowska A, Kusmierek J. Miscoding properties of isoguanine (2-oxoadenine) studied in an AMV reverse transcriptase in vitro system. Acta Biochim Pol. 1996;43:247-54 pubmed
    ..Our results indicate also that formation of the reverse transcriptase catalyzed base pairs between iG and A, G or C can occur only at a low frequency, comparable to the frequency, of mismatches of.(ABSTRACT TRUNCATED)..
  65. Pavlickova L, Stys D, Soucek M, Urban J, Hrusková O, Sedlacek J, et al. 15gag proteinase of myeloblastosis-associated virus: specificity studies with substrate-based inhibitors. Arch Biochem Biophys. 1992;298:753-6 pubmed
    ..The data obtained provide evidence that the MAV proteinase has generally lower specificity and poorer binding than the HIV proteinase...
  66. Lipsick J, Baluda M. The myb oncogene. Gene Amplif Anal. 1986;4:73-98 pubmed
  67. Sears J, Khan A. Single-tube fluorescent product-enhanced reverse transcriptase assay with Ampliwax (STF-PERT) for retrovirus quantitation. J Virol Methods. 2003;108:139-42 pubmed
    ..The STF-PERT assay can be used to quantitate low amounts of retrovirus in clinical and research materials and to evaluate retrovirus contamination in cell substrates and biological products in human use...
  68. Spencer J, Benkel B, Chan M, Nadin Davis S. Evidence for virus closely related to avian myeloblastosis-associated virus type 1 in a commercial stock of chickens. Avian Pathol. 2003;32:383-90 pubmed
  69. Martynov B, Shirokova E, Jasko M, Victorova L, Krayevsky A. Effect of triphosphate modifications in 2'-deoxynucleoside 5'-triphosphates on their specificity towards various DNA polymerases. FEBS Lett. 1997;410:423-7 pubmed
    ..properties of dNTPs in DNA synthesis catalyzed by human placental DNA polymerases alpha and beta, avian myeloblastosis virus reverse transcriptase, and calf thymus terminal deoxynucleotidyl transferase...
  70. Krebs J, Kore A. Novel FRET-based assay to detect reverse transcriptase activity using modified dUTP analogues. Bioconjug Chem. 2008;19:185-91 pubmed publisher
    ..Our results indicate that the wild-type AMV (avian myeloblastosis virus) enzyme is slightly more stable at 43 degrees C than the HIV-1 (human immunodeficiency virus) or MMLV (..
  71. Sano K, Odawara F, Nakano T, Morimatsu S, Nakamura T, Saitoh Y, et al. Comparable sensitivities for detection of HIV-1 reverse transcriptase (RT) and other polymerases by RT assays requiring no radioisotopic materials. J Virol Methods. 1995;53:235-44 pubmed
    ..Two RTs from Rous-associated virus 2 (RAV-2) and avian myeloblastosis virus (AMV), one polymerase from Escherichia coli (Pol-I) and one recombinant RT of human immunodeficiency ..
  72. Engelke U, Whittaker L, Lipsick J. Weak transcriptional activation is sufficient for transformation by v-Myb. Virology. 1995;208:467-77 pubmed
  73. Sooknanan R, Howes M, Read L, Malek L. Fidelity of nucleic acid amplification with avian myeloblastosis virus reverse transcriptase and T7 RNA polymerase. Biotechniques. 1994;17:1077-80, 1083-5 pubmed
    ..alternate steps of DNA synthesis from an RNA template and RNA synthesis from a DNA template, using avian myeloblastosis virus (AMV) reverse transcriptase and T7 RNA polymerase, respectively...
  74. Suzuki K, Craddock B, Okamoto N, Kano T, Steigbigel R. Detection of human immunodeficiency virus (HIV) by colorimetric assay for reverse transcriptase activity on magnetic beads. Biotechnol Appl Biochem. 1993;18 ( Pt 1):37-44 pubmed
    ..The total assay time, including the RT reaction step, was less than 1 h, and therefore provides a reliable rapid assay for detection and quantification of HIV...
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