fowlpox virus

Summary

Summary: The type species of the genus AVIPOXVIRUS. It is the etiologic agent of FOWLPOX.

Top Publications

  1. Boyle D, Heine H. Recombinant fowlpox virus vaccines for poultry. Immunol Cell Biol. 1993;71 ( Pt 5):391-7 pubmed
    ..of recombinant vaccinia viruses have been readily adapted to the construction of recombinant viruses based on fowlpox virus (rFPV)...
  2. Singh P, Schnitzlein W, Tripathy D. Reticuloendotheliosis virus sequences within the genomes of field strains of fowlpox virus display variability. J Virol. 2003;77:5855-62 pubmed
    Nine field strains of fowlpox virus (FPV) isolated during a 24-year span from geographically diverse outbreaks of fowlpox in the United States were screened for the presence of reticuloendotheliosis virus (REV) sequences in their genomes ..
  3. Boulanger D, Smith T, Skinner M. Morphogenesis and release of fowlpox virus. J Gen Virol. 2000;81:675-87 pubmed
    Release of fowlpox virus (FWPV) as extracellular enveloped virus (EEV) appears to proceed both by the budding of intracellular mature virus (IMV) through the plasma membrane and by the fusion of intracellular enveloped virus (IEV) with ..
  4. Zhang L, Jin N, Song Y, Wang H, Ma H, Li Z, et al. Construction and characterization of a recombinant fowlpox virus containing HIV-1 multi-epitope-p24 chimeric gene in mice. Sci China C Life Sci. 2007;50:212-20 pubmed
    ..5x20) of fowlpox virus (FPV) transfer vector pUTA2...
  5. Butter C, Sturman T, Baaten B, Davison T. Protection from infectious bursal disease virus (IBDV)-induced immunosuppression by immunization with a fowlpox recombinant containing IBDV-VP2. Avian Pathol. 2003;32:597-604 pubmed
    ..These results indicate that measurement of immunosuppression could be a useful strategy for assessing the efficacy of vaccines to protect against the consequences of IBDV infection...
  6. Yang G, Li J, Zhang X, Zhao Q, Liu Q, Gong P. Eimeria tenella: construction of a recombinant fowlpox virus expressing rhomboid gene and its protective efficacy against homologous infection. Exp Parasitol. 2008;119:30-6 pubmed publisher
    A recombinant fowlpox virus (rFPV) expressing the Eimeria tenella rhomboid gene was constructed and its protective efficacy against homologous infection in chickens determined...
  7. Laidlaw S, Anwar M, Thomas W, Green P, Shaw K, Skinner M. Fowlpox virus encodes nonessential homologs of cellular alpha-SNAP, PC-1, and an orphan human homolog of a secreted nematode protein. J Virol. 1998;72:6742-51 pubmed
    The genome of fowlpox virus (FWPV), type species of the Avipoxviridae, is considerably rearranged compared with that of vaccinia virus (the prototypic poxvirus and type species of the Orthopoxviridae) and is 30% larger...
  8. Afonso C, Tulman E, Lu Z, Zsak L, Kutish G, Rock D. The genome of fowlpox virus. J Virol. 2000;74:3815-31 pubmed
    Here we present the genomic sequence, with analysis, of a pathogenic fowlpox virus (FPV). The 288-kbp FPV genome consists of a central coding region bounded by identical 9...
  9. Davidson I, Shkoda I, Perk S. Integration of the reticuloendotheliosis virus envelope gene into the poultry fowlpox virus genome is not universal. J Gen Virol. 2008;89:2456-60 pubmed publisher
    b>Fowlpox virus (FWPV) is found worldwide in poultry and wild birds...

More Information

Publications66

  1. Qiao C, Yu K, Jiang Y, Jia Y, Tian G, Liu M, et al. Protection of chickens against highly lethal H5N1 and H7N1 avian influenza viruses with a recombinant fowlpox virus co-expressing H5 haemagglutinin and N1 neuraminidase genes. Avian Pathol. 2003;32:25-32 pubmed
    ..In this study, a recombinant fowlpox virus co-expressing HA (H5 subtype) and NA (NI subtype)genes of AIV was evaluated for its ability to protect ..
  2. Tadese T, Fitzgerald S, Reed W. Detection and differentiation of re-emerging fowlpox virus (FWPV) strains carrying integrated reticuloendotheliosis virus (FWPV-REV) by real-time PCR. Vet Microbiol. 2008;127:39-49 pubmed
    Current strains of fowlpox virus (FWPV) carrying circulating reticuloendotheliosis virus (FWPV-REV) sequence are becoming more pathogenic to poultry...
  3. Shi X, Zhao Y, Gao H, Jing Z, Wang M, Cui H, et al. Evaluation of recombinant fowlpox virus expressing infectious bronchitis virus S1 gene and chicken interferon-? gene for immune protection against heterologous strains. Vaccine. 2011;29:1576-82 pubmed publisher
    A recombinant fowlpox virus (rFPV-IFN?S1) that co-expressed the infectious bronchitis virus (IBV) S1 gene and the chicken interferon-? gene has been constructed...
  4. Webster D, Dunachie S, Vuola J, Berthoud T, Keating S, Laidlaw S, et al. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proc Natl Acad Sci U S A. 2005;102:4836-41 pubmed
    ..Here, we report that substitution of plasmid DNA as the priming vector with a specific attenuated recombinant fowlpox virus, FP9, vaccine in such prime-boost regimes can elicit complete sterile protection that can last for 20 months...
  5. Pacchioni S, Volonté L, Zanotto C, Pozzi E, De Giuli Morghen C, Radaelli A. Canarypox and fowlpox viruses as recombinant vaccine vectors: an ultrastructural comparative analysis. Arch Virol. 2010;155:915-24 pubmed publisher
    Due to their natural host-range restriction to avian species, canarypox virus (CP) and fowlpox virus (FP) represent efficient and safe vaccine vectors, as they correctly express transgenes in human cells, elicit complete immune responses,..
  6. Skinner M, Laidlaw S, Eldaghayes I, Kaiser P, Cottingham M. Fowlpox virus as a recombinant vaccine vector for use in mammals and poultry. Expert Rev Vaccines. 2005;4:63-76 pubmed
    Live vaccines against fowlpox virus, which causes moderate pathology in poultry and is the type species of the Avipoxvirus genus, were developed in the 1920s...
  7. Cheng J, Liu X, Pen D, Liu H. [Recombinant fowlpox virus expressing HA from subtype H9N2 of avian influenza virus and its protective immunity against homologous challenge in chickens]. Wei Sheng Wu Xue Bao. 2002;42:442-7 pubmed
    ..In order to generate recombinant fowlpox virus expressing HA(rFPV-HA), the recombinant transferring vector 1175HA was used to transfect the chicken embryo ..
  8. Qiao C, Yu K, Jiang Y, Li C, Tian G, Wang X, et al. Development of a recombinant fowlpox virus vector-based vaccine of H5N1 subtype avian influenza. Dev Biol (Basel). 2006;124:127-32 pubmed
    The genetic stability of the recombinant fowlpox virus (named rFPV-HA-NA) was confirmed by serial passage on chicken embryo fibroblast (CEF) cells...
  9. Chaudhry Y, Skinner M, Goodfellow I. Recovery of genetically defined murine norovirus in tissue culture by using a fowlpox virus expressing T7 RNA polymerase. J Gen Virol. 2007;88:2091-100 pubmed
    ..In this report, a reverse-genetics system for MNV is described, using a fowlpox virus (FWPV) recombinant expressing T7 RNA polymerase to recover genetically defined MNV in tissue culture for the ..
  10. Pozzi E, Basavecchia V, Zanotto C, Pacchioni S, Morghen C, Radaelli A. Construction and characterization of recombinant fowlpox viruses expressing human papilloma virus E6 and E7 oncoproteins. J Virol Methods. 2009;158:184-9 pubmed publisher
    ..In this study, two new fowlpox virus (FPV) recombinants encoding the HPV-16 E6 and E7 proteins were engineered and evaluated for their correct ..
  11. Zheng M, Jin N, Zhang H, Jin M, Lu H, Ma M, et al. Construction and immunogenicity of a recombinant fowlpox virus containing the capsid and 3C protease coding regions of foot-and-mouth disease virus. J Virol Methods. 2006;136:230-7 pubmed
    ..A recombinant fowlpox virus (vUTAL3CP1) containing FMDV capsid polypeptide and 3C coding regions of O/NY00 was constructed and evaluated ..
  12. Bissa M, Pacchioni S, Zanotto C, De Giuli Morghen C, Radaelli A. GFP co-expression reduces the A33R gene expression driven by a fowlpox vector in replication permissive and non-permissive cell lines. J Virol Methods. 2013;187:172-6 pubmed publisher
    ..Therefore, GFP co-expression does not prevent, but can reduce the level of a vaccine protein, and may affect the protective efficacy of the immune response...
  13. Banadyga L, Veugelers K, Campbell S, Barry M. The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis. J Virol. 2009;83:7085-98 pubmed publisher
    ..We previously characterized the fowlpox virus protein FPV039 as a Bcl-2-like antiapoptotic protein that inhibits apoptosis by interacting with and ..
  14. Srinivasan V, Schnitzlein W, Tripathy D. Fowlpox virus encodes a novel DNA repair enzyme, CPD-photolyase, that restores infectivity of UV light-damaged virus. J Virol. 2001;75:1681-8 pubmed
    b>Fowlpox virus (FPV), a pathogen of poultry, can persist in desiccated scabs shed from infected hosts...
  15. Zanotto C, Pozzi E, Pacchioni S, Volonté L, De Giuli Morghen C, Radaelli A. Canarypox and fowlpox viruses as recombinant vaccine vectors: a biological and immunological comparison. Antiviral Res. 2010;88:53-63 pubmed publisher
    ..The production of retrovirus-like particles, the longer transgene expression, and a balanced cytokine induction may confer to fowlpox-based recombinants the ability to elicit a better immune response...
  16. Boyle D, Coupar B, Gibbs A, Seigman L, Both G. Fowlpox virus thymidine kinase: nucleotide sequence and relationships to other thymidine kinases. Virology. 1987;156:355-65 pubmed
    The thymidine kinase (TK) gene of fowlpox virus (FPV) is located in a 2.2-kb HindIII-ClaI fragment derived from a 5.5-kb EcoR1 fragment of the FPV genome...
  17. Zanotto C, Pozzi E, Pacchioni S, Bissa M, De Giuli Morghen C, Radaelli A. Construction and characterisation of a recombinant fowlpox virus that expresses the human papilloma virus L1 protein. J Transl Med. 2011;9:190 pubmed publisher
  18. Wang Y, Sun Y, Tian Z, Shi X, Tong G, Liu S, et al. Protection of chickens against infectious bronchitis by a recombinant fowlpox virus co-expressing IBV-S1 and chicken IFNgamma. Vaccine. 2009;27:7046-52 pubmed publisher
    A fowlpox virus expressing the chicken infectious bronchitis virus (IBV) S1 gene of the LX4 strain (rFPV-IBVS1) and a fowlpox virus co-expressing the S1 gene and the chicken type II interferon gene (rFPV-IBVS1-ChIFNgamma) were ..
  19. Culyba M, Hwang Y, Minkah N, Bushman F. DNA binding and cleavage by the fowlpox virus resolvase. J Biol Chem. 2009;284:1190-201 pubmed publisher
    ..We found that fowlpox virus resolvase was much more tractable...
  20. Yun S, Zhang W, Liu W, Zhang X, Chen S, Wu Y, et al. [Construction of recombinant fowlpox virus coexpressing HA gene from H5N1 avian influenza virus and chicken interleukin-2 gene and assessment of its protective efficacy]. Bing Du Xue Bao. 2009;25:430-6 pubmed
    ..The p12LSH5AIL2 was then used to transfect the chicken embryo fibroblasts (CEF) pre-infected with a wild-type fowlpox virus 282E4 strain, to generate a recombinant fowlpox virus coexpressing the inserted HA and chiIL2 genes (rFPV-..
  21. Hemachandra A, Puls R, Sirivichayakul S, Kerr S, Thantiworasit P, Ubolyam S, et al. An HIV-1 clade A/E DNA prime, recombinant fowlpox virus boost vaccine is safe, but non-immunogenic in a randomized phase I/IIa trial in Thai volunteers at low risk of HIV infection. Hum Vaccin. 2010;6:835-40 pubmed publisher
    ..Previously demonstrated safe and highly immunogenic in non-human primates, this study assessed DNA (pHIS-HIV-AE) prime, recombinant fowlpox (rFPV-HIV-AE) boost vaccines in humans...
  22. Ma M, Jin N, Shen G, Zhu G, Liu H, Zheng M, et al. Immune responses of swine inoculated with a recombinant fowlpox virus co-expressing P12A and 3C of FMDV and swine IL-18. Vet Immunol Immunopathol. 2008;121:1-7 pubmed
    ..Control groups were inoculated with wild-type fowlpox virus (wtFPV)...
  23. Lousberg E, Diener K, Fraser C, Phipps S, Foster P, Chen W, et al. Antigen-specific T-cell responses to a recombinant fowlpox virus are dependent on MyD88 and interleukin-18 and independent of Toll-like receptor 7 (TLR7)- and TLR9-mediated innate immune recognition. J Virol. 2011;85:3385-96 pubmed publisher
    b>Fowlpox virus (FWPV) is a double-stranded DNA virus long used as a live-attenuated vaccine against poultry diseases, but more recent interest has focused on its use as a mammalian vaccine vector...
  24. Binns M, Tomley F, Campbell J, Boursnell M. Comparison of a conserved region in fowlpox virus and vaccinia virus genomes and the translocation of the fowlpox virus thymidine kinase gene. J Gen Virol. 1988;69 ( Pt 6):1275-83 pubmed
    ..of a clustered set of genes which are conserved in orthopoxviruses has been determined for the avipoxvirus, fowlpox virus. The arrangement of the genes in fowlpox virus is nearly identical to that in vaccinia virus, and genes which ..
  25. Shen G, Jin N, Ma M, Jin K, Zheng M, Zhuang T, et al. Immune responses of pigs inoculated with a recombinant fowlpox virus coexpressing GP5/GP3 of porcine reproductive and respiratory syndrome virus and swine IL-18. Vaccine. 2007;25:4193-202 pubmed
    ..Control groups were inoculated with wild-type fowlpox virus (wtFPV)...
  26. Radaelli A, Bonduelle O, Beggio P, Mahe B, Pozzi E, Elli V, et al. Prime-boost immunization with DNA, recombinant fowlpox virus and VLP(SHIV) elicit both neutralizing antibodies and IFNgamma-producing T cells against the HIV-envelope protein in mice that control env-bearing tumour cells. Vaccine. 2007;25:2128-38 pubmed
    Different primings with DNA and fowlpox virus (FP) recombinants or FP alone were used in a pre-clinical trial to evaluate and compare immunogenicity and efficacy against HIV/SHIV...
  27. Hertig C, Coupar B, Gould A, Boyle D. Field and vaccine strains of fowlpox virus carry integrated sequences from the avian retrovirus, reticuloendotheliosis virus. Virology. 1997;235:367-76 pubmed
    ..We report here that field and vaccine strains of fowlpox virus (FPV) carry integrated sequences from the avian retrovirus, reticuloendotheliosis virus (REV)...
  28. Radaelli A, Zanotto C, Perletti G, Elli V, Vicenzi E, Poli G, et al. Comparative analysis of immune responses and cytokine profiles elicited in rabbits by the combined use of recombinant fowlpox viruses, plasmids and virus-like particles in prime-boost vaccination protocols against SHIV. Vaccine. 2003;21:2052-64 pubmed
    ..6P) followed by VLP boosting generated a T helper (Th0) profile and a good Ab titer, suggesting a potential protocol to be tested in the SHIV-macaque model of HIV-1 infection...
  29. Coupar B, Purcell D, Thomson S, Ramshaw I, Kent S, Boyle D. Fowlpox virus vaccines for HIV and SHIV clinical and pre-clinical trials. Vaccine. 2006;24:1378-88 pubmed
    DNA prime and recombinant fowlpox virus (rFPV) boost vaccines were designed to express multiple HIV or SIV antigens for use in human clinical trials and in pre-clinical trials in macaques...
  30. Taylor J, Paoletti E. Fowlpox virus as a vector in non-avian species. Vaccine. 1988;6:466-8 pubmed
    ..We have taken advantage of this restricted host range in fowlpox virus to engineer recombinant vector viruses for use in the poultry industry and in vaccination of non-avian species.
  31. Ogawa R, Calvert J, Yanagida N, Nazerian K. Insertional inactivation of a fowlpox virus homologue of the vaccinia virus F12L gene inhibits the release of enveloped virions. J Gen Virol. 1993;74 ( Pt 1):55-64 pubmed
    ..7 kb HindIII fragment of the fowlpox virus (FPV) genome resulted in the generation of stable recombinants...
  32. Laidlaw S, Skinner M. Comparison of the genome sequence of FP9, an attenuated, tissue culture-adapted European strain of Fowlpox virus, with those of virulent American and European viruses. J Gen Virol. 2004;85:305-22 pubmed
    The 266 kbp genome sequence of plaque-purified, tissue culture-adapted, attenuated European Fowlpox virus FP9 has been determined and compared with the 288 kbp sequence of a pathogenic US strain (FPVUS)...
  33. Karaca K, Swayne D, Grosenbaugh D, Bublot M, Robles A, Spackman E, et al. Immunogenicity of fowlpox virus expressing the avian influenza virus H5 gene (TROVAC AIV-H5) in cats. Clin Diagn Lab Immunol. 2005;12:1340-2 pubmed
    Vaccination of cats with fowlpox virus expressing the avian influenza (AI) virus H5 hemagglutinin gene (TROVAC AI) resulted in detectable hemagglutination inhibition (HI) antibody responses to the homologous A/Turkey/Ireland/1378/83 (..
  34. Qiao C, Jiang Y, Tian G, Wang X, Li C, Xin X, et al. Recombinant fowlpox virus vector-based vaccine completely protects chickens from H5N1 avian influenza virus. Antiviral Res. 2009;81:234-8 pubmed publisher
    ..study, the immune efficacy and hemagglutination inhibition (HI) antibody responses induced by a recombinant fowlpox virus (FPV) vector-based rFPV-HA-NA vaccine was evaluated in SPF and commercial chickens...
  35. Singh P, Schnitzlein W, Tripathy D. Construction and characterization of a fowlpox virus field isolate whose genome lacks reticuloendotheliosis provirus nucleotide sequences. Avian Dis. 2005;49:401-8 pubmed
    b>Fowlpox virus (FWPV) has been isolated from vaccinated chicken flocks during subsequent fowlpox outbreaks that were characterized by a high degree of mortality and significant economic losses...
  36. Weli S, Nilssen Ø, Traavik T. Morphogenesis of fowlpox virus in a baby hamster kidney cell line. Med Electron Microsc. 2004;37:225-35 pubmed
    b>Fowlpox virus (FWPV) recombinant vaccines are presently being tested as an antihuman immunodeficiency virus vaccine for humans. However, biosafety, as well as the morphogenesis of FWPV in mammalian cells, are not well understood...
  37. Emery S, Workman C, Puls R, Bloch M, Baker D, Bodsworth N, et al. Randomized, placebo-controlled, phase I/IIa evaluation of the safety and immunogenicity of fowlpox virus expressing HIV gag-pol and interferon-gamma in HIV-1 infected subjects. Hum Vaccin. 2005;1:232-8 pubmed
    ..Although safe, neither vaccine construct appeared to possess detectable T-cell mediated anti-HIV immunogenic properties in HIV infected individuals, as measured by standard T cell assays...
  38. Boot H, ter Huurne A, Peeters B, Gielkens A. Efficient rescue of infectious bursal disease virus from cloned cDNA: evidence for involvement of the 3'-terminal sequence in genome replication. Virology. 1999;265:330-41 pubmed
    ..cDNA behind a T7 promoter, by transfecting these plasmids into cells which were infected with a recombinant Fowlpox virus that expressed T7 RNA polymerase...
  39. Lamien C, Meda A, Mans J, Romito M, Nacoulma O, Viljoen G. Inhibition of fowlpox virus by an aqueous acetone extract from galls of Guiera senegalensis J. F. Gmel (Combretaceae). J Ethnopharmacol. 2005;96:249-53 pubmed
    ..acetone extract from the galls of Guiera senegalensis was screened for in vitro antiviral activity against fowlpox virus (FPV)...
  40. Pozzi E, Zanotto C, Pacchioni S, De Giuli Morghen C, Radaelli A. MHC-restricted cytotoxic T-lymphocyte assay: an improved method based on normal and SV40-immortalized rabbit epidermal target cells. J Virol Methods. 2009;155:77-81 pubmed publisher
    ..The results show that: (i) skin-derived rabbit fibroblasts can be used as target cells after infection with a fowlpox virus recombinant; (ii) SV40-immortalized skin fibroblasts appear to be more appropriate for repeated assays; (iii) ..
  41. Kelleher A, Puls R, Bebbington M, Boyle D, Ffrench R, Kent S, et al. A randomized, placebo-controlled phase I trial of DNA prime, recombinant fowlpox virus boost prophylactic vaccine for HIV-1. AIDS. 2006;20:294-7 pubmed
    An HIV-vaccine consisting of a DNA prime, recombinant fowlpox virus (rFPV) boost was evaluated in a double-blind placebo controlled trial...
  42. Cottingham M, van Maurik A, Zago M, Newton A, Anderson R, Howard M, et al. Different levels of immunogenicity of two strains of Fowlpox virus as recombinant vaccine vectors eliciting T-cell responses in heterologous prime-boost vaccination strategies. Clin Vaccine Immunol. 2006;13:747-57 pubmed
    ..These "passage-specific" alterations are hypothesized to be involved in determining the immunogenicity of fowlpox virus as a recombinant vaccine vector.
  43. Alvarez Lajonchere L, Amador Cañizares Y, Frías R, Milian Y, Musacchio A, Guerra I, et al. Immunization with a recombinant fowlpox virus expressing a hepatitis C virus core-E1 polyprotein variant, protects mice and African green monkeys (Chlorocebus aethiops sabaeus) against challenge with a surrogate vaccinia virus. Biotechnol Appl Biochem. 2008;51:97-105 pubmed publisher
    ..In the present work a recombinant fowlpox virus, FPCoE1, expressing a truncated HCV core-E1 polyprotein, was generated...
  44. Beukema E, Brown M, Hayball J. The potential role of fowlpox virus in rational vaccine design. Expert Rev Vaccines. 2006;5:565-77 pubmed
    ..b>Fowlpox virus, the prototypical member of the Avipoxvirus genus, is particularly suitable, as it is also incapable of ..
  45. Hghihghi H, Read L, Mohammadi H, Pei Y, Ursprung C, Nagy E, et al. Characterization of host responses against a recombinant fowlpox virus-vectored vaccine expressing the hemagglutinin antigen of an avian influenza virus. Clin Vaccine Immunol. 2010;17:454-63 pubmed publisher
    There currently are commercial fowlpox virus (FPV)-vectored vaccines for use in chickens, including TROVAC-AIV H5, which expresses the hemagglutinin (HA) antigen of an avian influenza virus and can confer immunity against avian influenza ..
  46. Sun H, Wang Y, Tong G, Zhang P, Miao D, Zhi H, et al. Protection of chickens from Newcastle disease and infectious laryngotracheitis with a recombinant fowlpox virus co-expressing the F, HN genes of Newcastle disease virus and gB gene of infectious laryngotracheitis virus. Avian Dis. 2008;52:111-7 pubmed
    A recombinant fowlpox virus (rFPV) coexpressing the Newcastle disease virus (NDV) fusion and hemagglutinin-neuraminidase genes and infectious laryngothracheitis virus (ILTV) glycoprotein B gene was constructed...
  47. Li X, Jin N, Mi Z, Lian H, Sun L, Li X, et al. Antitumor effects of a recombinant fowlpox virus expressing Apoptin in vivo and in vitro. Int J Cancer. 2006;119:2948-57 pubmed
    ..To explore the use of the Apoptin gene in cancer gene therapy, we constructed a recombinant fowlpox virus expressing the Apoptin protein (vFV-Apoptin) and compared the tumor-killing activity of the recombinant virus ..
  48. Banadyga L, Gerig J, Stewart T, Barry M. Fowlpox virus encodes a Bcl-2 homologue that protects cells from apoptotic death through interaction with the proapoptotic protein Bak. J Virol. 2007;81:11032-45 pubmed publisher
    ..to encode an array of effective inhibitors of apoptosis, members of the Avipoxvirus genus, which includes fowlpox virus, encode proteins with Bcl-2 homology...
  49. Diallo I, Taylor J, Gibson J, Hoad J, de Jong A, Hewitson G, et al. Diagnosis of a naturally occurring dual infection of layer chickens with fowlpox virus and gallid herpesvirus 1 (infectious laryngotracheitis virus). Avian Pathol. 2010;39:25-30 pubmed publisher
    ..The diagnosis was based on virus isolation of gallid herpesvirus 1 (GaHV-1) in chicken kidney cells and fowlpox virus (FWPV) in 9-day-old chicken embryonated eggs inoculated via the chorioallantoic membrane...
  50. Kent S, Zhao A, Best S, Chandler J, Boyle D, Ramshaw I. Enhanced T-cell immunogenicity and protective efficacy of a human immunodeficiency virus type 1 vaccine regimen consisting of consecutive priming with DNA and boosting with recombinant fowlpox virus. J Virol. 1998;72:10180-8 pubmed
    ..Plasmid DNA and recombinant fowlpox virus (rFPV) vaccines are among the most promising safe HIV-1 vaccine candidates...
  51. Singh P, Kim T, Tripathy D. Identification and characterization of fowlpox virus strains using monoclonal antibodies. J Vet Diagn Invest. 2003;15:50-4 pubmed
    The use of 2 monoclonal antibodies (MAbs), P1D9 and P2D4, which recognize different fowlpox virus (FPV) antigens, for the identification and characterization of FPV strains was evaluated...
  52. Binns M, Boursnell M, Skinner M. Gene translocations in poxviruses: the fowlpox virus thymidine kinase gene is flanked by 15 bp direct repeats and occupies the locus which in vaccinia virus is occupied by the ribonucleotide reductase large subunit gene. Virus Res. 1992;24:161-72 pubmed
    By sequencing a fragment of 7351 bp the fowlpox virus thymidine kinase gene has been found to map to a position within the equivalent of the vaccinia HindIII I fragment...
  53. Skinner M, Moore J, Binns M, Smith G, Boursnell M. Deletion of fowlpox virus homologues of vaccinia virus genes between the 3 beta-hydroxysteroid dehydrogenase (A44L) and DNA ligase (A50R) genes. J Gen Virol. 1994;75 ( Pt 9):2495-8 pubmed
    A fragment of 4156 bp of fowlpox virus (FPV) genomic DNA contains homologues of vaccinia virus 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD; A44L) and DNA ligase (A50R) genes...
  54. Dale C, De Rose R, Stratov I, Chea S, Montefiori D, Thomson S, et al. Efficacy of DNA and fowlpox virus priming/boosting vaccines for simian/human immunodeficiency virus. J Virol. 2004;78:13819-28 pubmed
    ..We analyzed a set of multigenic simian/human immunodeficiency virus (SHIV) DNA and fowlpox virus priming and boosting vaccines for immunogenicity and protective efficacy in outbred pigtail macaques...
  55. Zeytin H, Reali E, Zaharoff D, Rogers C, Schlom J, Greiner J. Targeted delivery of murine IFN-gamma using a recombinant fowlpox virus: NK cell recruitment to regional lymph nodes and priming of tumor-specific host immunity. J Interferon Cytokine Res. 2008;28:73-87 pubmed publisher
    ..if mice were vaccinated with MC38 cells either pretreated with rIFN-gamma or infected with the wild-type fowlpox virus (FP-WT)...
  56. Liu A, Guardino A, Chinsangaram L, Goldstein M, Panicali D, Levy R. Therapeutic vaccination against murine lymphoma by intratumoral injection of recombinant fowlpox virus encoding CD40 ligand. Cancer Res. 2007;67:7037-44 pubmed
    ..In this study, we investigated the therapeutic antitumor effect of intratumoral administration of recombinant fowlpox virus encoding murine CD40L (rF-mCD40L) in a murine B-cell lymphoma model. BALB/c mice with established s.c...
  57. Emery S, Kelleher A, Workman C, Puls R, Bloch M, Baker D, et al. Influence of IFNgamma co-expression on the safety and antiviral efficacy of recombinant fowlpox virus HIV therapeutic vaccines following interruption of antiretroviral therapy. Hum Vaccin. 2007;3:260-7 pubmed
    ..The promising antiretrovirological effect supports further study of FC in a larger trial with a broader population of patients with HIV disease...