Summary: A subfamily of DNA vertebrate viruses, in the family PARVOVIRIDAE. There are three genera: PARVOVIRUS; ERYTHROVIRUS; and DEPENDOVIRUS.

Top Publications

  1. Sloots T, McErlean P, Speicher D, Arden K, Nissen M, Mackay I. Evidence of human coronavirus HKU1 and human bocavirus in Australian children. J Clin Virol. 2006;35:99-102 pubmed
    ..Children under the age of 2 years were most at risk of infection by these viruses which contribute significantly to the microbial burden among patients with respiratory tract disease during the colder months...
  2. Lau S, Woo P, Tse H, Fu C, Au W, Chen X, et al. Identification of novel porcine and bovine parvoviruses closely related to human parvovirus 4. J Gen Virol. 2008;89:1840-8 pubmed publisher
    ..The co-detection of porcine reproductive and respiratory syndrome virus, the agent associated with the recent 'high fever' disease outbreaks in pigs in China, from our porcine samples warrants further investigation...
  3. Ma X, Endo R, Ishiguro N, Ebihara T, Ishiko H, Ariga T, et al. Detection of human bocavirus in Japanese children with lower respiratory tract infections. J Clin Microbiol. 2006;44:1132-4 pubmed
    ..7%) collected from children with lower respiratory tract infections. HBoV may be one of the causative agents of lower respiratory tract infections in young children...
  4. Fasina O, Stupps S, Figueroa Cuilan W, Pintel D. Minute Virus of Canines NP1 Protein Governs the Expression of a Subset of Essential Nonstructural Proteins via Its Role in RNA Processing. J Virol. 2017;91: pubmed publisher
    ..b>IMPORTANCE The Parvovirinae are small nonenveloped icosahedral viruses that are important pathogens in many animal species, including ..
  5. Canuti M, Eis Huebinger A, Deijs M, de Vries M, Drexler J, Oppong S, et al. Two novel parvoviruses in frugivorous New and Old World bats. PLoS ONE. 2011;6:e29140 pubmed publisher
    ..We also provide evidence that a variety of Parvovirinae are able to cause active infection in bats and that they are widely distributed in these animals with different ..
  6. Hargitai R, Pankovics P, Kertész A, Bíró H, Boros Ã, Phan T, et al. Detection and genetic characterization of a novel parvovirus distantly related to human bufavirus in domestic pigs. Arch Virol. 2016;161:1033-7 pubmed publisher
    ..Swine/Zsana3/2013/HUN is highly prevalent in domestic pigs and potentially represents a novel parvovirus species in the subfamily Parvovirinae.
  7. de Souza W, Dennis T, Fumagalli M, Araujo J, Sabino Santos G, Maia F, et al. Novel Parvoviruses from Wild and Domestic Animals in Brazil Provide New Insights into Parvovirus Distribution and Diversity. Viruses. 2018;10: pubmed publisher
    ..species (six of which have not been described previously), representing six distinct genera in the subfamily Parvovirinae...
  8. Sasaki M, Gonzalez G, Wada Y, Setiyono A, Handharyani E, Rahmadani I, et al. Divergent bufavirus harboured in megabats represents a new lineage of parvoviruses. Sci Rep. 2016;6:24257 pubmed publisher
    Bufavirus is a recently recognized member of the genus Protoparvovirus in the subfamily Parvovirinae. It has been reported that human bufavirus was detected predominantly in patients with diarrhoea in several countries...
  9. Palinski R, Mitra N, Hause B. Discovery of a novel Parvovirinae virus, porcine parvovirus 7, by metagenomic sequencing of porcine rectal swabs. Virus Genes. 2016;52:564-7 pubmed publisher
    ..Quantitative PCR screening of 182 porcine diagnostic samples found a total of 16 positives (8.6 %). Together, these data suggest that PPV7 is a highly divergent novel parvovirus prevalent within the US swine. ..

More Information


  1. Shi C, Liu Y, Hu X, Xiong J, Zhang B, Yuan Z. A metagenomic survey of viral abundance and diversity in mosquitoes from Hubei province. PLoS ONE. 2015;10:e0129845 pubmed publisher
    ..were identified, and six torque tenosus virus1 in family Anelloviridae, three porcine parvoviruses in subfamily Parvovirinae and a Culex tritaeniorhynchus rhabdovirus in Family Rhabdoviridae were preliminarily characterized...
  2. Fasina O, Dong Y, Pintel D. NP1 Protein of the Bocaparvovirus Minute Virus of Canines Controls Access to the Viral Capsid Genes via Its Role in RNA Processing. J Virol. 2016;90:1718-28 pubmed publisher
    ..MVC NP1 is a 22-kDa nuclear phosphoprotein unique to the genus Bocaparvovirus of the Parvovirinae which we have shown governs suppression of (pA)p independently of viral genome replication...
  3. Cibulski S, Teixeira T, Dos Santos H, de Sales Lima F, Scheffer C, Varela A, et al. Ungulate copiparvovirus 1 (bovine parvovirus 2): characterization of a new genotype and associated viremia in different bovine age groups. Virus Genes. 2016;52:134-7 pubmed publisher
    ..The genome organization of new BPV2 genotype retains the two ORFs typical of members of the Parvovirinae with 86.4 % of overall nucleotide sequence identities in comparison to other members of the subfamily...
  4. Sivakumar V, Sarathi M, Venkatesan C, Sivaraj A, Hameed A. Experimental exposure of Artemia to hepatopancreatic parvo-like virus and subsequent transmission to post-larvae of Penaeus monodon. J Invertebr Pathol. 2009;102:191-5 pubmed publisher
    ..This will enable us to understand better whether Artemia is a carrier of this virus and if so the mechanism involved...
  5. Gava D, Souza C, Mores T, Argenti L, Streck A, Canal C, et al. Dynamics of vanishing of maternally derived antibodies of Ungulate protoparvovirus 1 suggests an optimal age for gilts vaccination. Trop Anim Health Prod. 2017;49:1085-1088 pubmed publisher
    ..73, n = 248, P < 0.001). The MDA decreased earlier and the antibody half-life was a little longer than previously reported. Based on these findings, UPV1 vaccination can be performed earlier than usual. ..
  6. Cibulski S, Teixeira T, Varela A, Scheffer C, Santos H, Lima F, et al. Ungulate copiparvovirus 2 in healthy and postweaning multisystemic wasting syndrome-affected pigs. Trop Anim Health Prod. 2017;49:945-949 pubmed publisher
    ..001). Although the copy numbers were lower in younger PMWS-affected individuals, this result sheds some light on the possible association between PPV4 viral load detection in this group and the immune impairment caused by PMWS. ..
  7. Foulongne V, Olejnik Y, Perez V, Elaerts S, Rodière M, Segondy M. Human bocavirus in French children. Emerg Infect Dis. 2006;12:1251-3 pubmed
    ..We report the epidemiologic and clinical features observed from a 1-year retrospective study of HBoV infection in young children hospitalized with a respiratory tract infection...
  8. Adlhoch C, Kaiser M, Ellerbrok H, Pauli G. High prevalence of porcine Hokovirus in German wild boar populations. Virol J. 2010;7:171 pubmed publisher
    ..The German PHoV sequences from wild boars showed a close relationship with sequences of isolates from Hong Kong...
  9. Simon M. Simian parvoviruses: biology and implications for research. Comp Med. 2008;58:47-50 pubmed
  10. Yang S, Liu D, Wang Y, Qu F, He Y, Sun Z, et al. Bufavirus Protoparvovirus in feces of wild rats in China. Virus Genes. 2016;52:130-3 pubmed publisher
    ..Our epidemiologic study indicated that the prevalence rate of RatBuV in the cohort of 40 wild rats is 12.5 % (5/40), which is higher than that of BuV in humans in a previous study. ..
  11. Pan Y, Zeng Q, Zhu C, Hua X, Wang M, Pan K, et al. Frequency and characterization of porcine hokovirus (PHoV) in domestic pigs in eastern China. Arch Virol. 2012;157:1785-8 pubmed publisher
    ..The results provide evidence that there are differences between PHoV in China compared to early isolates. PHoV infections are more frequent in 0- to 6-week-old pigs than in older ones...
  12. Leuchs B, Roscher M, Müller M, Kürschner K, Rommelaere J. Standardized large-scale H-1PV production process with efficient quality and quantity monitoring. J Virol Methods. 2016;229:48-59 pubmed publisher
    ..For quick, sensitive determination of physical particles (and hence, particle-to-infectivity ratios), a "Capsid-ELISA" was developed, based on a novel monoclonal antibody that specifically targets assembled capsids. ..
  13. Doyle S. The detection of parvoviruses. Methods Mol Biol. 2011;665:213-31 pubmed publisher
    ..This chapter describes the current status of detection systems for all the aforementioned parvoviruses, with particular emphasis on Erythrovirus detection by serological, NAT, and immunological approaches...
  14. Nims R, Zhou S. Intra-family differences in efficacy of inactivation of small, non-enveloped viruses. Biologicals. 2016;44:456-62 pubmed publisher
    ..This should be taken into consideration by regulatory agencies and biologics manufacturers designing viral clearance and facility disinfection validation studies, and developers and evaluators of viral disinfectants. ..
  15. Weissbrich B, Neske F, Schubert J, Tollmann F, Blath K, Blessing K, et al. Frequent detection of bocavirus DNA in German children with respiratory tract infections. BMC Infect Dis. 2006;6:109 pubmed
    ..Some of these cases may be caused by the recently described human bocavirus (hBoV). The aim of this study was to investigate the frequency and the potential clinical relevance of hBoV in pediatric patients...
  16. Li B, Sun B, Du L, Mao A, Wen L, Ni Y, et al. Development of a loop-mediated isothermal amplification assay for the detection of porcine hokovirus. J Virol Methods. 2013;193:415-8 pubmed publisher
    ..These results show that the LAMP assay is a simple, rapid, sensitive and specific method for detecting PHoV. It does not require specialized equipment and can be used to detect PHoV both in the laboratory and in the field...
  17. Chen H, Tang Y, Dou Y, Zheng X, Diao Y. Evidence for Vertical Transmission of Novel Duck-Origin Goose Parvovirus-Related Parvovirus. Transbound Emerg Dis. 2016;63:243-7 pubmed publisher
    ..N-GPV infection did not reduce the fertilization rate and hatchability. These results indicate possible vertical transmission of N-GPV and suggest that it may be transmitted from breeder ducks to ducklings in ovo. ..
  18. Souza C, Streck A, Gonçalves K, Pinto L, Ravazzolo A, de Barcellos D, et al. Phylogenetic characterization of the first Ungulate tetraparvovirus 2 detected in pigs in Brazil. Braz J Microbiol. 2016;47:513-7 pubmed publisher
    ..The phylogenetic analysis demonstrated that Brazilian UTV2 sequences were more closely related to sequences from Europe and United States. ..
  19. Chung J, Han T, Kim C, Kim S. Bocavirus infection in hospitalized children, South Korea. Emerg Infect Dis. 2006;12:1254-6 pubmed
    ..The virus was detected in 27 (8.0%) of 336 tested specimens, including 17 (7.5%) of 225 virus-negative specimens, collected from children with acute lower respiratory tract infection...
  20. Owens L, McElnea C, Snape N, Harris L, Smith M. Prevalence and effect of spawner-isolated mortality virus on the hatchery phases of Penaeus monodon and P. merguiensis in Australia. Dis Aquat Organ. 2003;53:101-6 pubmed
    ..006). Data from 38 ponds showed 6.71% of losses were due to SMV. If these losses were consistent across the entire industry, the annual loss due to SMV would have been approximately AUD 3 million in 1999/2000...
  21. Lu X, Chittaganpitch M, Olsen S, Mackay I, Sloots T, Fry A, et al. Real-time PCR assays for detection of bocavirus in human specimens. J Clin Microbiol. 2006;44:3231-5 pubmed
    ..5%) were reproducibly positive for HBoV by one or both targets. Our data confirm the possible association of HBoV infection with pneumonia and demonstrate the utility of these real-time PCR assays for HBoV detection...