iridovirus

Summary

Summary: A genus of IRIDOVIRIDAE comprising small iridescent insect viruses. The infected larvae and purified virus pellets exhibit a blue to purple iridescence.

Top Publications

  1. Dang L, Kondo H, Hirono I, Aoki T. Inhibition of red seabream iridovirus (RSIV) replication by small interfering RNA (siRNA) in a cell culture system. Antiviral Res. 2008;77:142-9 pubmed
    ..we describe an antiviral activity of a siRNA that targets the major capsid protein (MCP) gene of red seabream iridovirus (RSIV), a marine fish-pathogenic virus, in a cell culture system...
  2. Qin Q, Lam T, Sin Y, Shen H, Chang S, Ngoh G, et al. Electron microscopic observations of a marine fish iridovirus isolated from brown-spotted grouper, Epinephelus tauvina. J Virol Methods. 2001;98:17-24 pubmed
    The morphogenesis and the ultrastructure of a marine fish iridovirus isolated from diseased grouper, Epinephelus tauvina were studied by electron microscopy. The virus was grown on a marine fish cell line (GP) at 25 degrees C...
  3. Lua D, Yasuike M, Hirono I, Aoki T. Transcription program of red sea bream iridovirus as revealed by DNA microarrays. J Virol. 2005;79:15151-64 pubmed
    Red sea bream iridovirus (RSIV) has been identified as the causative agent of a serious disease in red sea bream and at least 30 other marine fish species...
  4. Qin Q, Wu T, Jia T, Hegde A, Zhang R. Development and characterization of a new tropical marine fish cell line from grouper, Epinephelus coioides susceptible to iridovirus and nodavirus. J Virol Methods. 2006;131:58-64 pubmed
    ..GS cell cultures showed advanced cytopathic effects after infection with a pathogenic grouper iridovirus (Singapore grouper iridovirus, SGIV) or with a grouper nodavirus (Epinephelus tauvina nervous necrosis virus, ..
  5. Kim T, Jung T, Lee J. Expression and serological application of a capsid protein of an iridovirus isolated from rock bream, Oplegnathus fasciatus (Temminck & Schlegel). J Fish Dis. 2007;30:691-9 pubmed
    ..This paper reports the cloning, sequencing, and expression of the rock bream iridovirus (RBIV) major capsid protein (MCP) in an Escherichia coli expression system for subsequent immunological studies...
  6. Jakob N, Muller K, Bahr U, Darai G. Analysis of the first complete DNA sequence of an invertebrate iridovirus: coding strategy of the genome of Chilo iridescent virus. Virology. 2001;286:182-96 pubmed
    Chilo iridescent virus (CIV), the type species of the genus Iridovirus, a member of the Iridoviridae family, is highly pathogenic for a variety of insect larvae...
  7. Guo C, Wu Y, Yang L, Yang X, He J, Mi S, et al. Infectious spleen and kidney necrosis virus (a fish iridovirus) enters Mandarin fish fry cells via caveola-dependent endocytosis. J Virol. 2012;86:2621-31 pubmed publisher
    ..As a fish iridovirus, ISKNV entry into MFF-1 cells is different from the clathrin-mediated endocytosis of frog virus 3 entry into ..
  8. He J, Deng M, Weng S, Li Z, Zhou S, Long Q, et al. Complete genome analysis of the mandarin fish infectious spleen and kidney necrosis iridovirus. Virology. 2001;291:126-39 pubmed
    ..In addition, one major repeated sequence showing significant homology to the Red Sea bream iridovirus (RSIV) genome was identified...
  9. Chen X, Lin K, Wang X. Outbreaks of an iridovirus disease in maricultured large yellow croaker, Larimichthys crocea (Richardson), in China. J Fish Dis. 2003;26:615-9 pubmed

More Information

Publications72

  1. Lin P, Huang Y, John J, Chang Y, Yuan C, Chen W, et al. Iridovirus Bcl-2 protein inhibits apoptosis in the early stage of viral infection. Apoptosis. 2008;13:165-76 pubmed
    The grouper iridovirus (GIV) belongs to the family Iridoviridae, whose genome contains an antiapoptotic B-cell lymphoma (Bcl)-2-like gene. This study was carried-out to understand whether GIV blocks apoptosis in its host...
  2. Drury S, Gough R, Calvert I. Detection and isolation of an iridovirus from chameleons (Chamaeleo quadricornis and Chamaeleo hoehnelli) in the United Kingdom. Vet Rec. 2002;150:451-2 pubmed
  3. Weber E, Waltzek T, Young D, Twitchell E, Gates A, Vagelli A, et al. Systemic iridovirus infection in the Banggai cardinalfish (Pterapogon kauderni Koumans 1933). J Vet Diagn Invest. 2009;21:306-20 pubmed
    ..The objective of the current study was to characterize an iridovirus causing systemic infection of wild-caught Pterapogon kauderni Koumans 1933 (Banggai cardinalfish)...
  4. Cui H, Yan Y, Wei J, Huang X, Huang Y, Ouyang Z, et al. Identification and functional characterization of an interferon regulatory factor 7-like (IRF7-like) gene from orange-spotted grouper, Epinephelus coioides. Dev Comp Immunol. 2011;35:672-84 pubmed publisher
    ..up-regulated after stimulation with Vibrio vulnificus, Staphylococcus aureus and Singapore grouper iridovirus (SGIV)...
  5. Bollinger T, Mao J, Schock D, Brigham R, Chinchar V. Pathology, isolation, and preliminary molecular characterization of a novel iridovirus from tiger salamanders in Saskatchewan. J Wildl Dis. 1999;35:413-29 pubmed
    All iridovirus was confirmed to be the cause of an epizootic in larval and adult tiger salamanders (Ambystoma tigrinum diaboli) from four separate ponds in southern Saskatchewan (Canada) during the summer of 1997...
  6. Huang X, Huang Y, Gong J, Yan Y, Qin Q. Identification and characterization of a putative lipopolysaccharide-induced TNF-alpha factor (LITAF) homolog from Singapore grouper iridovirus. Biochem Biophys Res Commun. 2008;373:140-5 pubmed publisher
    ..Here, a novel LITAF homolog encoded by Singapore grouper iridovirus (SGIV LITAF) was identified and characterized...
  7. Song W, Qin Q, Qiu J, Huang C, Wang F, Hew C. Functional genomics analysis of Singapore grouper iridovirus: complete sequence determination and proteomic analysis. J Virol. 2004;78:12576-90 pubmed
    Here we report the complete genome sequence of Singapore grouper iridovirus (SGIV). Sequencing of the random shotgun and restriction endonuclease genomic libraries showed that the entire SGIV genome consists of 140,131 nucleotide bp...
  8. Ting J, Wu M, Tsai C, Lin C, Guo I, Chang C. Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase. J Gen Virol. 2004;85:2883-92 pubmed
    ..Here, a novel piscine viral PNP gene that was identified from grouper iridovirus (GIV), a causative agent of an epizootic fish disease, is reported...
  9. Marina C, Ibarra J, Arredondo Jiménez J, Fernandez Salas I, Valle J, Williams T. Sublethal iridovirus disease of the mosquito Aedes aegypti is due to viral replication not cytotoxicity. Med Vet Entomol. 2003;17:187-94 pubmed
    ..only 5-17% decrease of R0 following treatments with deactivated virus, compared to controls. Sublethal effects of IIV-6 in Ae. aegypti appear to be mainly due to virus replication, rather than cytotoxic effects of the viral inoculum...
  10. Bromenshenk J, Henderson C, Wick C, Stanford M, Zulich A, Jabbour R, et al. Iridovirus and microsporidian linked to honey bee colony decline. PLoS ONE. 2010;5:e13181 pubmed publisher
    ..We next need to characterize the IIV and Nosema that we detected and develop management practices to reduce honey bee losses. ..
  11. Wan Q, Gong J, Huang X, Huang Y, Zhou S, Ou Yang Z, et al. Identification and characterization of a novel capsid protein encoded by Singapore grouper iridovirus ORF038L. Arch Virol. 2010;155:351-9 pubmed publisher
    Singapore grouper iridovirus (SGIV) is an important pathogen isolated from grouper, Epinephelus tauvina, and characterized as a novel ranavirus...
  12. Imajoh M, Sugiura H, Oshima S. Morphological changes contribute to apoptotic cell death and are affected by caspase-3 and caspase-6 inhibitors during red sea bream iridovirus permissive replication. Virology. 2004;322:220-30 pubmed
    Red sea bream iridovirus (RSIV) of the Iridoviridae family is a causative agent of lethal infections in many cultured marine fish species in southwestern Japan. RSIV-induced apoptosis was divided as follows: (1)...
  13. Huang Y, Huang X, Yan Y, Cai J, Ouyang Z, Cui H, et al. Transcriptome analysis of orange-spotted grouper (Epinephelus coioides) spleen in response to Singapore grouper iridovirus. BMC Genomics. 2011;12:556 pubmed publisher
    ..The emergence of infectious viral diseases, including iridovirus and betanodavirus, have severely affected food products based on this species, causing heavy economic losses...
  14. Qin Q, Shi C, Gin K, Lam T. Antigenic characterization of a marine fish iridovirus from grouper, Epinephelus spp. J Virol Methods. 2002;106:89-96 pubmed
    ..Antigenic properties of a pathogenic iridovirus isolated from grouper, Epinephelus spp...
  15. Wang C, Shih H, Ku C, Chen S. Studies on epizootic iridovirus infection among red sea bream, Pagrus major (Temminck & Schlegel), cultured in Taiwan. J Fish Dis. 2003;26:127-33 pubmed
    ..bp fragments were produced from the viral DNA using as a template 1-F and 1-R primers derived from red seabream iridovirus (RSIV) from red sea bream in Japan...
  16. Sudthongkong C, Miyata M, Miyazaki T. Iridovirus disease in two ornamental tropical freshwater fishes: African lampeye and dwarf gourami. Dis Aquat Organ. 2002;48:163-73 pubmed
    ..We found African lampeye Aplocheilichthys normani and dwarf gourami Colisa lalia suffering from an iridovirus infection just after being imported by tropical fish wholesalers from Singapore...
  17. Song W, Lin Q, Joshi S, Lim T, Hew C. Proteomic studies of the Singapore grouper iridovirus. Mol Cell Proteomics. 2006;5:256-64 pubmed
    The Singapore grouper iridovirus (SGIV) genome consists of a double-stranded circular DNA of 140,131 base pairs with 162 predicted open reading frames...
  18. Ao J, Chen X. Identification and characterization of a novel gene encoding an RGD-containing protein in large yellow croaker iridovirus. Virology. 2006;355:213-22 pubmed
    ..and functional characterization of a gene encoding an RGD-containing protein (037L) from large yellow croaker iridovirus (LYCIV), a causative agent of epizootics among large yellow croaker, Pseudosciaena crocea...
  19. Wang F, Bi X, Chen L, Hew C. ORF018R, a highly abundant virion protein from Singapore grouper iridovirus, is involved in serine/threonine phosphorylation and virion assembly. J Gen Virol. 2008;89:1169-78 pubmed publisher
    b>Iridovirus is an important pathogen causing serious diseases among wild, cultured and ornamental fish...
  20. Go J, Lancaster M, Deece K, Dhungyel O, Whittington R. The molecular epidemiology of iridovirus in Murray cod (Maccullochella peelii peelii) and dwarf gourami (Colisa lalia) from distant biogeographical regions suggests a link between trade in ornamental fish and emerging iridoviral diseases. Mol Cell Probes. 2006;20:212-22 pubmed
    ..There was almost complete homology (99.95%) over 4,527 bp between Murray cod iridovirus (MCIV) and an iridovirus (DGIV) present in dwarf gourami (Colisa lalia) that had died in aquarium shops in ..
  21. Jakob N, Kleespies R, Tidona C, Muller K, Gelderblom H, Darai G. Comparative analysis of the genome and host range characteristics of two insect iridoviruses: Chilo iridescent virus and a cricket iridovirus isolate. J Gen Virol. 2002;83:463-70 pubmed
    The iridovirus isolate termed cricket iridovirus (CrIV) was isolated in 1996 from Gryllus campestris L. and Acheta domesticus L. (both Orthoptera, Gryllidae)...
  22. Teng Y, Hou Z, Gong J, Liu H, Xie X, Zhang L, et al. Whole-genome transcriptional profiles of a novel marine fish iridovirus, Singapore grouper iridovirus (SGIV) in virus-infected grouper spleen cell cultures and in orange-spotted grouper, Epinephulus coioides. Virology. 2008;377:39-48 pubmed publisher
    A DNA microarray containing all Singapore grouper iridovirus (SGIV) open reading frames (ORFs) was constructed to map the viral gene transcriptional profiles in virus-infected grouper spleen (GS) cells and in spleen tissues of virus-..
  23. He J, Lu L, Deng M, He H, Weng S, Wang X, et al. Sequence analysis of the complete genome of an iridovirus isolated from the tiger frog. Virology. 2002;292:185-97 pubmed
    ..The results from this study indicated that TFV may belong to the genus Ranavirus of the family Iridoviridae...
  24. Tsai C, Lin C, Chang C. Analysis of codon usage bias and base compositional constraints in iridovirus genomes. Virus Res. 2007;126:196-206 pubmed
    The codon usage bias and the base composition variations in the available 12 complete iridovirus genome sequences have been investigated...
  25. Chitnis N, D Costa S, Paul E, Bilimoria S. Modulation of iridovirus-induced apoptosis by endocytosis, early expression, JNK, and apical caspase. Virology. 2008;370:333-42 pubmed
    ..This is the first report of JNK signal requirement during apoptosis induction by an insect virus...
  26. Williams T. Natural invertebrate hosts of iridoviruses (Iridoviridae). Neotrop Entomol. 2008;37:615-32 pubmed
    ..I show that the rate of publication on IIVs has slowed from 1990 to the present, and I draw a number of conclusions and suggestions from the host list and make recommendations for future research efforts...
  27. Zhou S, Wan Q, Huang Y, Huang X, Cao J, Ye L, et al. Proteomic analysis of Singapore grouper iridovirus envelope proteins and characterization of a novel envelope protein VP088. Proteomics. 2011;11:2236-48 pubmed publisher
    Singapore grouper iridovirus (SGIV) is an enveloped virus causing heavy economic losses to marine fish culture...
  28. Do J, Moon C, Kim H, Ko M, Kim S, Son J, et al. Complete genomic DNA sequence of rock bream iridovirus. Virology. 2004;325:351-63 pubmed
    b>Iridovirus is a causative agent of epizootics among cultured rock bream (Oplegnathus fasciatus) in Korea. Here, we report the complete genomic sequence of rock bream iridovirus (RBIV)...
  29. Tapiovaara H, Olesen N, Linden J, Rimaila Pärnänen E, von Bonsdorff C. Isolation of an iridovirus from pike-perch Stizostedion lucioperca. Dis Aquat Organ. 1998;32:185-93 pubmed
    ..the virus was stained by rabbit antisera against EHN (epizootic haematopoietic necrosis) virus, sheatfish iridovirus and cod iridovirus...
  30. Kuo H, Wang T, Hsu H, Chen P, Lee S, Chen Y, et al. Nervous necrosis virus replicates following the embryo development and dual infection with iridovirus at juvenile stage in grouper. PLoS ONE. 2012;7:e36183 pubmed publisher
    Infection of virus (such as nodavirus and iridovirus) and bacteria (such as Vibrio anguillarum) in farmed grouper has been widely reported and caused large economic losses to Taiwanese fish aquaculture industry since 1979...
  31. Jeong J, Cho H, Jun L, Hong S, Chung J, Jeong H. Transmission of iridovirus from freshwater ornamental fish (pearl gourami) to marine fish (rock bream). Dis Aquat Organ. 2008;82:27-36 pubmed publisher
    ..tested positive for PGIV-SP by 2-step polymerase chain reaction (PCR). Thus, PGIV-SP from freshwater ornamental fish may have crossed both environmental and species barriers to infect marine fish such as rock bream...
  32. Zhao Z, Ke F, Shi Y, Zhou G, Gui J, Zhang Q. Rana grylio virus thymidine kinase gene: an early gene of iridovirus encoding for a cytoplasmic protein. Virus Genes. 2009;38:345-52 pubmed publisher
    ..Collectively, current data indicate that RGV TK was an early gene of iridovirus which encoded a cytoplasmic protein in fish cells.
  33. Shinmoto H, Taniguchi K, Ikawa T, Kawai K, Oshima S. Phenotypic diversity of infectious red sea bream iridovirus isolates from cultured fish in Japan. Appl Environ Microbiol. 2009;75:3535-41 pubmed publisher
    ..We explored the emergence of red sea bream iridovirus (RSIV) on a fish farm in Japan, and we specifically endeavored to quantify genetic and phenotypic differences ..
  34. Tamaru Y, Ohtsuka M, Kato K, Manabe S, Kuroda K, Sanada M, et al. Application of the arming system for the expression of the 380R antigen from red sea bream iridovirus (RSIV) on the surface of yeast cells: a first step for the development of an oral vaccine. Biotechnol Prog. 2006;22:949-53 pubmed
    ..In this study, we describe the expression of one of the target antigens, 380R, from the red sea bream iridovirus (RSIV), which is one of the most common viral diseases in the cultured marine fish Pagrus major in Japan, using ..
  35. Paul E, Chitnis N, Henderson C, Kaul R, D Costa S, Bilimoria S. Induction of apoptosis by iridovirus virion protein extract. Arch Virol. 2007;152:1353-64 pubmed
    Chilo iridescent virus (CIV; IIV-6) is the type member of the genus Iridovirus (family Iridoviridae, large icosahedral cytoplasmic DNA viruses)...
  36. López M, Rojas J, Vandame R, Williams T. Parasitoid-mediated transmission of an iridescent virus. J Invertebr Pathol. 2002;80:160-70 pubmed
    ..We suggest that the polyphagous habits of many noctuid parasitoids combined with the catholic host range of most IIVs may represent a mechanism for the transmission of IIVs between different host species in the field...
  37. Williams T, Barbosa Solomieu V, Chinchar V. A decade of advances in iridovirus research. Adv Virus Res. 2005;65:173-248 pubmed
  38. Raverty S, Hedrick R, Henry J, Saksida S. Diagnosis of sturgeon iridovirus infection in farmed white sturgeon in British Columbia. Can Vet J. 2003;44:327-8 pubmed
  39. Xie J, Lu L, Deng M, Weng S, Zhu J, Wu Y, et al. Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference. Virology. 2005;338:43-52 pubmed
    ..were tested for silencing expression of the major capsid protein (MCP) encoded by tiger frog virus (TFV), an iridovirus causing severe disease in fish...
  40. Hunter W, LaPointe S. Iridovirus infection of cell cultures from the Diaprepes root weevil, Diaprepes abbreviatus. J Insect Sci. 2003;3:37 pubmed
    ..Root weevil cells were successfully infected in vitro with a known insect virus, Invertebrate Iridescent Virus 6. Potential uses of insect cell cultures and insect viruses are discussed...
  41. Hunter W, LaPointe S, Sinisterra X, Achor D, Funk C. Iridovirus in the root weevil Diaprepes abbreviatus. J Insect Sci. 2003;3:9 pubmed
    ..Discovery of new pathogens against root weevils may provide new management tools for development of control strategies based on induced epizootics. This is the first report of a virus infecting D. abbreviatus...
  42. Henderson C, Johnson C, Lodhi S, Bilimoria S. Replication of Chilo iridescent virus in the cotton boll weevil, Anthonomus grandis, and development of an infectivity assay. Arch Virol. 2001;146:767-75 pubmed
    ..Chilo iridescent virus (CIV) is the type species for genus Iridovirus, family Iridoviridae: large, icosahedral cytoplasmic viruses containing a double-stranded DNA genome...
  43. Hunter W, Patte C, Sinisterra X, Achor D, Funk C, Polston J. Discovering new insect viruses: whitefly iridovirus (Homoptera: Aleyrodidae: Bemisia tabaci). J Invertebr Pathol. 2001;78:220-5 pubmed
    ..and DNA sequencing confirmed that the virus discovered infecting the whitefly cell cultures was an iridovirus. Sequence analysis showed that the amplimer (893 bp) had a 95% homology to the invertebrate iridescent virus ..
  44. Huang X, Huang Y, Ouyang Z, Xu L, Yan Y, Cui H, et al. Singapore grouper iridovirus, a large DNA virus, induces nonapoptotic cell death by a cell type dependent fashion and evokes ERK signaling. Apoptosis. 2011;16:831-45 pubmed publisher
    ..Singapore grouper iridovirus (SGIV), a novel iridovirus of genus Ranavirus, causes high mortality and heavy economic losses in grouper ..
  45. Wong C, Young V, Kleffmann T, Ward V. Genomic and proteomic analysis of invertebrate iridovirus type 9. J Virol. 2011;85:7900-11 pubmed publisher
    ..Invertebrate iridovirus type 9 (IIV-9; Wiseana iridovirus) is a member of the major phylogenetic group of iridoviruses for which there ..
  46. Yan Y, Cui H, Jiang S, Huang Y, Huang X, Wei S, et al. Identification of a novel marine fish virus, Singapore grouper iridovirus-encoded microRNAs expressed in grouper cells by Solexa sequencing. PLoS ONE. 2011;6:e19148 pubmed publisher
    ..Singapore grouper iridovirus (SGIV) is a pathogenic iridovirus that has severely affected grouper aquaculture in China and Southeast Asia...
  47. Chao C, Chen C, Lai Y, Lin C, Huang H. Histological, ultrastructural, and in situ hybridization study on enlarged cells in grouper Epinephelus hybrids infected by grouper iridovirus in Taiwan (TGIV). Dis Aquat Organ. 2004;58:127-42 pubmed
    Grouper iridovirus in Taiwan (TGIV) infection in the Epinephelus hybrid is a major problem in the grouper industry. ATPase gene sequences indicate that this virus is closely related to cell hypertrophy iridoviruses...
  48. Huang Y, Huang X, Liu H, Gong J, Ouyang Z, Cui H, et al. Complete sequence determination of a novel reptile iridovirus isolated from soft-shelled turtle and evolutionary analysis of Iridoviridae. BMC Genomics. 2009;10:224 pubmed publisher
    Soft-shelled turtle iridovirus (STIV) is the causative agent of severe systemic diseases in cultured soft-shelled turtles (Trionyx sinensis)...
  49. Caipang C, Takano T, Hirono I, Aoki T. Genetic vaccines protect red seabream, Pagrus major, upon challenge with red seabream iridovirus (RSIV). Fish Shellfish Immunol. 2006;21:130-8 pubmed
    ..capsid protein (MCP) and an open reading frame (ORF) containing a transmembrane domain against red seabream iridovirus (RSIV)...
  50. Mao X, Zhou S, Xu D, Gong J, Cui H, Qin Q. Rapid and sensitive detection of Singapore grouper iridovirus by loop-mediated isothermal amplification. J Appl Microbiol. 2008;105:389-97 pubmed publisher
    The aim of this paper was to develop a loop-mediated isothermal amplification (LAMP) method for rapid, sensitive and inexpensive detection of Singapore grouper iridovirus (SGIV) in grouper (GP), Epinephelus sp.
  51. Johnson A, Wendland L, Norton T, Belzer B, Jacobson E. Development and use of an indirect enzyme-linked immunosorbent assay for detection of iridovirus exposure in gopher tortoises (Gopherus polyphemus) and eastern box turtles (Terrapene carolina carolina). Vet Microbiol. 2010;142:160-7 pubmed publisher
    ..To determine the prevalence of iridovirus exposure in free-ranging gopher tortoises (Gopherus polyphemus) in the southeast United States, an indirect ..
  52. Gong J, Huang Y, Huang X, Zhang R, Qin Q. Nuclear-export-signal-dependent protein translocation of dUTPase encoded by Singapore grouper iridovirus. Arch Virol. 2010;155:1069-76 pubmed publisher
    ..In the present study, the expression pattern and translocation of a dUTPase homolog encoded by Singapore grouper iridovirus (SGIV) were elucidated...
  53. Docherty D, Meteyer C, Wang J, Mao J, Case S, Chinchar V. Diagnostic and molecular evaluation of three iridovirus-associated salamander mortality events. J Wildl Dis. 2003;39:556-66 pubmed
    ..Electron microscopy of ultra thin sections of the same tissues revealed iridovirus-like particles within the inclusions...
  54. Zhou J, Wei J, Xu D, Cui H, Yan Y, Ou Yang Z, et al. Molecular cloning and characterization of two novel hepcidins from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2011;30:559-68 pubmed publisher
    ..The replication of Singapore grouper iridovirus (SGIV) was inhibited in the EC-hepcidin1 and EC-hepcidin2 over-expressed stable transfected fish cell lines (GS/..
  55. Lu L, Zhou S, Chen C, Weng S, Chan S, He J. Complete genome sequence analysis of an iridovirus isolated from the orange-spotted grouper, Epinephelus coioides. Virology. 2005;339:81-100 pubmed
    Orange-spotted grouper iridovirus (OSGIV) was the causative agent of serious systemic diseases with high mortality in the cultured orange-spotted grouper, Epinephelus coioides. Here we report the complete genome sequence of OSGIV...
  56. Chen L, Tran B, Lin Q, Lim T, Wang F, Hew C. iTRAQ analysis of Singapore grouper iridovirus infection in a grouper embryonic cell line. J Gen Virol. 2008;89:2869-76 pubmed publisher
    We report, here, the first proteomics study of a grouper embryonic cell line (GEC) infected by Singapore grouper iridovirus (SGIV)...
  57. Tokarz R, Firth C, Street C, Cox Foster D, Lipkin W. Lack of evidence for an association between Iridovirus and colony collapse disorder. PLoS ONE. 2011;6:e21844 pubmed publisher
    ..i) we surveyed healthy and CCD colonies from the United States and Israel for the presence of members of the Iridovirus genus and (ii) we reanalyzed metagenomics data previously generated from RNA pools of CCD colonies for the ..
  58. Huang Y, Huang X, Cai J, Ye F, Guan L, Liu H, et al. Construction of green fluorescent protein-tagged recombinant iridovirus to assess viral replication. Virus Res. 2011;160:221-9 pubmed publisher
    ..Here, we identified soft-shelled turtle iridovirus (STIV) ORF55 as an envelope protein (VP55), and developed a recombinant STIV expressing an enhanced green ..
  59. Yeh C, Chen Y, Wu M, Chen C, Yuan C, Pan K, et al. Differential display of grouper iridovirus-infected grouper cells by immunostaining. Biochem Biophys Res Commun. 2008;372:674-80 pubmed publisher
    Grouper iridovirus (GIV) is one of the most devastating infectious pathogens of aquaculture fish. When infecting a susceptible cell line, such as GK-2, GIV causes antigenic changes in host cellular proteins...
  60. Drennan J, LaPatra S, Siple J, Ireland S, Cain K. Transmission of white sturgeon iridovirus in Kootenai River white sturgeon Acipenser transmontanus. Dis Aquat Organ. 2006;70:37-45 pubmed
    It is thought that white sturgeon iridovirus (WSIV) is transmitted vertically from adult white sturgeon Acipenser transmontanus to progeny, and that wild adults are carriers of this virus...
  61. Xu D, Wei J, Cui H, Gong J, Yan Y, Lai R, et al. Differential profiles of gene expression in grouper Epinephelus coioides, infected with Singapore grouper iridovirus, revealed by suppression subtractive hybridization and DNA microarray. J Fish Biol. 2010;77:341-60 pubmed publisher
    ..in the spleen of orange-spotted grouper Epinephelus coioides after 5 days of infection with Singapore grouper iridovirus (SGIV)...
  62. Sudthongkong C, Miyata M, Miyazaki T. Viral DNA sequences of genes encoding the ATPase and the major capsid protein of tropical iridovirus isolates which are pathogenic to fishes in Japan, South China Sea and Southeast Asian countries. Arch Virol. 2002;147:2089-109 pubmed
    Tropical iridovirus infection causes severe epizootic resulting in mass mortalities and large economic losses in freshwater ornamental fishes cultured in Southeast Asian countries, in wild fish seedlings captured in South China Sea, and ..
  63. Caipang C, Hirono I, Aoki T. Immunogenicity, retention and protective effects of the protein derivatives of formalin-inactivated red seabream iridovirus (RSIV) vaccine in red seabream, Pagrus major. Fish Shellfish Immunol. 2006;20:597-609 pubmed
    ..virus was previously found to be efficient in protecting fish against challenge with red seabream iridovirus (RSIV), a DNA virus belonging to the Iridoviridae family...