polyomaviridae

Summary

Summary: A family of small, non-enveloped DNA viruses, infecting mainly MAMMALS.

Top Publications

  1. Chen C, Kincaid R, Seo G, Bennett M, Sullivan C. Insights into Polyomaviridae microRNA function derived from study of the bandicoot papillomatosis carcinomatosis viruses. J Virol. 2011;85:4487-500 pubmed publisher
    Several different members of the Polyomaviridae, including some human pathogens, encode microRNAs (miRNAs) that lie antisense with respect to the early gene products, the tumor (T) antigens...
  2. Johne R, Buck C, Allander T, Atwood W, Garcea R, Imperiale M, et al. Taxonomical developments in the family Polyomaviridae. Arch Virol. 2011;156:1627-34 pubmed publisher
    The Polyomaviridae Study Group of the International Committee on Taxonomy of Viruses (ICTV) has recommended several taxonomical revisions, as follows: The family Polyomaviridae, which is currently constituted as a single genus (..
  3. Woolford L, Rector A, Van Ranst M, Ducki A, Bennett M, Nicholls P, et al. A novel virus detected in papillomas and carcinomas of the endangered western barred bandicoot (Perameles bougainville) exhibits genomic features of both the Papillomaviridae and Polyomaviridae. J Virol. 2007;81:13280-90 pubmed publisher
    ..genome revealed a novel prototype virus exhibiting genomic properties of both the Papillomaviridae and the Polyomaviridae. Papillomaviral properties included a large genome size ( approximately 7...
  4. Gerits N, Moens U. Agnoprotein of mammalian polyomaviruses. Virology. 2012;432:316-26 pubmed publisher
    ..Members of the Polyomaviridae family have been isolated in birds (Avipolyomavirus) and mammals (Orthopolyomavirus and Wukipolyomavirus)...
  5. Fagrouch Z, Sarwari R, Lavergne A, Delaval M, de Thoisy B, Lacoste V, et al. Novel polyomaviruses in South American bats and their relationship to other members of the family Polyomaviridae. J Gen Virol. 2012;93:2652-7 pubmed publisher
    ..Interestingly, two lineages cluster with PyVs found in chimpanzees, orangutans and gorillas. In addition, one group of bat PyVs is genetically related to the human Merkel cell polyomavirus...
  6. Neske F, Blessing K, Ullrich F, Pröttel A, Wolfgang Kreth H, Weissbrich B. WU polyomavirus infection in children, Germany. Emerg Infect Dis. 2008;14:680-1 pubmed publisher
  7. Libbey J, Fujinami R. Complete Genome Sequence of Murine Pneumotropic Virus (Polyomaviridae) Clone pKV(37-1). Genome Announc. 2016;4: pubmed publisher
    ..The protein coding regions (large and small T antigens, viral proteins 1 to 3) showed multiple regions of high amino acid identity to the human, simian, and bovine polyomaviruses. ..
  8. Forbes B, Gissmann L, Pawlita M. Detection of individual virus-infected cells by filter in situ hybridization. Mol Cell Probes. 1988;2:245-53 pubmed
    ..Infection can be diagnosed even if only one out of 20,000 cells in a culture contains replicating virus. This assay may be of value as a diagnostic tool in other viral systems. ..
  9. Daoust P, Wadowska D, Kibenge F, Campagnoli R, Latimer K, Ritchie B. Proliferative pododermatitis associated with virus-like particles in a northern gannet. J Wildl Dis. 2000;36:378-82 pubmed
    ..To our knowledge, papovavirus-like particles have not been recognized previously in this avian species. ..

More Information

Publications92

  1. Kumar A, Joo W, Meinke G, Moine S, Naumova E, Bullock P. Evidence for a structural relationship between BRCT domains and the helicase domains of the replication initiators encoded by the Polyomaviridae and Papillomaviridae families of DNA tumor viruses. J Virol. 2008;82:8849-62 pubmed publisher
    ..presented that BRCT-related regions are present in the helicase domains of the viral initiators encoded by the Polyomaviridae and Papillomaviridae viral families...
  2. Chen J, Van Dyke T. Uniform cell-autonomous tumorigenesis of the choroid plexus by papovavirus large T antigens. Mol Cell Biol. 1991;11:5968-76 pubmed
    ..Analysis of mosaic transgenic mice indicated further that T antigen exerts its mitogenic effect cell autonomously. These studies form the foundation for elucidating the role of various T-antigen subactivities in tumorigenesis. ..
  3. Madinda N, Ehlers B, Wertheim J, Akoua Koffi C, Bergl R, Boesch C, et al. Assessing Host-Virus Codivergence for Close Relatives of Merkel Cell Polyomavirus Infecting African Great Apes. J Virol. 2016;90:8531-41 pubmed publisher
    It has long been hypothesized that polyomaviruses (PyV; family Polyomaviridae) codiverged with their animal hosts. In contrast, recent analyses suggested that codivergence may only marginally influence the evolution of PyV...
  4. Hunter L, Pipas J. Isolation of a simian virus 40-simian agent 12 recombinant papovavirus that synthesizes a hybrid large tumour antigen. J Gen Virol. 1988;69 ( Pt 3):683-7 pubmed
    ..Hyb4001 synthesizes a hybrid T antigen with the amino-terminal 382 residues encoded by SV40, residues 383 to 449 encoded by SA12, and the carboxy-terminal 259 residues encoded by SV40. ..
  5. Ben Salem N, Moens U, Ehlers B. Genome Sequences of Murine Pneumotropic Virus (Polyomaviridae) Detected in Wild House Mice (Mus musculus). Genome Announc. 2016;4: pubmed publisher
    Using generic PCR, we identified a variant of murine pneumotropic virus (MptV) (family Polyomaviridae) in 3 wild house mice (Mus musculus)...
  6. Horníková L, Žíla V, Španielová H, Forstová J. Mouse Polyomavirus: Propagation, Purification, Quantification, and Storage. Curr Protoc Microbiol. 2015;38:14F.1.1-26 pubmed publisher
    Mouse polyomavirus (MPyV) is a member of the Polyomaviridae family, which comprises non-enveloped tumorigenic viruses infecting various vertebrates including humans and causing different pathogenic responses in the infected organisms...
  7. Libbey J, Fujinami R. Variable Genome Sequences of the Murine Pneumotropic Virus (Polyomaviridae) Regulatory Region Isolated from an Infected Mouse Tissue Viral Suspension. Genome Announc. 2016;4: pubmed publisher
    ..The lungs, liver, spleen, and kidneys were the source of the tissue homogenate in order to mirror the heterogeneity of the virus population in vivo The regulatory region sequence was found to be highly variable. ..
  8. Anthony S, St Leger J, Navarrete Macias I, Nilson E, Sánchez León M, Liang E, et al. Identification of a novel cetacean polyomavirus from a common dolphin (Delphinus delphis) with Tracheobronchitis. PLoS ONE. 2013;8:e68239 pubmed publisher
    ..These results demonstrate that polyomaviruses can be associated with respiratory disease in cetaceans, and expand our knowledge of their diversity and clinical significance in marine mammals. ..
  9. Goodwin E, Atwood W, DiMaio D. High-throughput cell-based screen for chemicals that inhibit infection by simian virus 40 and human polyomaviruses. J Virol. 2009;83:5630-9 pubmed publisher
    ..Ellagic acid and spiperone also inhibited large T antigen expression by BK virus and JC virus, two important, pathogenic human polyomaviruses. ..
  10. Chen J, Neilson K, Van Dyke T. Lymphotropic papovavirus early region is specifically regulated transgenic mice and efficiently induces neoplasia. J Virol. 1989;63:2204-14 pubmed
    ..The origin of the lymphomas from B- and T-cell lineages suggests that the LPV early genes are expressed in and can transform both of these cell types in vivo. ..
  11. Pass D, Prus S, Riddell C. A papova-like virus infection of splendid parakeets (Neophema splendida). Avian Dis. 1987;31:680-4 pubmed
    ..One bird also had a hepatopathy characterized by hepatocyte enlargement and nuclear pleomorphism...
  12. Calgua B, Carratala A, Guerrero Latorre L, de Abreu Corrêa A, Kohn T, Sommer R, et al. UVC Inactivation of dsDNA and ssRNA Viruses in Water: UV Fluences and a qPCR-Based Approach to Evaluate Decay on Viral Infectivity. Food Environ Virol. 2014;6:260-8 pubmed publisher
    ..The families Adenoviridae and Polyomaviridae comprise human and animal pathogenic viruses that have been also proposed as indicators of fecal contamination ..
  13. Ben Salem N, Pérez de Val B, Martin M, Moens U, Ehlers B. Genome Sequence of Bovine Polyomavirus 1 Detected in a Salers Cow (Bos taurus) from Catalonia, Spain. Genome Announc. 2016;4: pubmed publisher
    We identified a variant of the first bovine polyomavirus (BPyV1; family Polyomaviridae) in a lymph node of a Salers cow...
  14. Ikeda K, Dorries K, ter Meulen V. Morphological and immunohistochemical studies of the central nervous system involvement in papovavirus K infection in mice. Acta Neuropathol. 1988;77:175-81 pubmed
    ..Therefore, this study has demonstrated that there is involvement of central nervous system during systemic K virus infection and that the infection involves predominantly brain capillary endothelial cells. ..
  15. Wutzler P, Sauerbrei A. Virucidal efficacy of a combination of 0.2% peracetic acid and 80% (v/v) ethanol (PAA-ethanol) as a potential hand disinfectant. J Hosp Infect. 2000;46:304-8 pubmed
  16. Das G, Shivakumar C, Todd S. Cell-specific modulation of the papovavirus promoters by tumor-suppressor protein p53 in the absence of large T-antigen. Oncogene. 1995;10:449-55 pubmed
    ..Well-defined viral promoters could thus provide us with an important tool for the identification and characterization of cellular factors that modulate p53-binding dependent gene regulation in animal cells. ..
  17. Sadeghi M, Wang Y, Ramqvist T, Aaltonen L, Pyöriä L, Toppinen M, et al. Multiplex detection in tonsillar tissue of all known human polyomaviruses. BMC Infect Dis. 2017;17:409 pubmed publisher
    ..past few years, eleven new human viruses have joined the two previously known members JCPyV and BKPyV of the Polyomaviridae family, by virtue of molecular methods...
  18. Boukoum H, Nahdi I, Sahtout W, Skiri H, Segondy M, Aouni M. BK and JC virus infections in healthy patients compared to kidney transplant recipients in Tunisia. Microb Pathog. 2016;97:204-8 pubmed publisher
    The human polyomaviruses BKPyV and JCPyV are members of Polyomaviridae family and after primary infections they persist as latent infection especially in the kidneys...
  19. Peterson L, Ostermann H, Fiegl M, Tischer J, Jaeger G, Rieger C. Reactivation of polyomavirus in the genitourinary tract is significantly associated with severe GvHD and oral mucositis following allogeneic stem cell transplantation. Infection. 2016;44:483-90 pubmed publisher
    BK-virus and JC-virus are the most common polyomaviridae associated with hemorrhagic cystitis in the allogeneic transplant setting...
  20. Delmas V, Bastien C, Scherneck S, Feunteun J. A new member of the polyomavirus family: the hamster papovavirus. Complete nucleotide sequence and transformation properties. EMBO J. 1985;4:1279-86 pubmed
    ..The cloned DNA can immortalize primary rat embryo cells and transform an established rat cell line. The viral DNA is stably integrated into the host genome. ..
  21. Carr M, Gonzalez G, Sasaki M, Ito K, Ishii A, Hang Ombe B, et al. Discovery of African bat polyomaviruses and infrequent recombination in the large T antigen in the Polyomaviridae. J Gen Virol. 2017;98:726-738 pubmed publisher
    ..from four newly proposed African bat PyV species employing the recently recommended criteria provided by the Polyomaviridae Study Group of the International Committee on Taxonomy of Viruses...
  22. Gurney E, Tamowski S, Deppert W. Antigenic binding sites of monoclonal antibodies specific for simian virus 40 large T antigen. J Virol. 1986;57:1168-72 pubmed
    ..Also, 3 of the 16 recognized the large T antigen of the human papovavirus BKV. ..
  23. Bethge T, Ajuh E, Hirsch H. Imperfect Symmetry of Sp1 and Core Promoter Sequences Regulates Early and Late Virus Gene Expression of the Bidirectional BK Polyomavirus Noncoding Control Region. J Virol. 2016;90:10083-10101 pubmed
    ..b>Polyomaviridae currently comprise more than 70 members, including 13 human polyomaviruses (PyVs), all of which share a ..
  24. Greenlee J, Phelps R, Stroop W. The major site of murine K papovavirus persistence and reactivation is the renal tubular epithelium. Microb Pathog. 1991;11:237-47 pubmed
    ..The present study represents the first instance in which the cell populations which support infection by a member of the polyomavirus subgroup in its natural host have been defined during acute, persistent, and reactivated infection. ..
  25. Gonzalez S, Escobar Serna D, Suarez O, Benavides X, Escobar Serna J, Lozano E. BK Virus Nephropathy in Kidney Transplantation: An Approach Proposal and Update on Risk Factors, Diagnosis, and Treatment. Transplant Proc. 2015;47:1777-85 pubmed publisher
    BK virus belongs to Polyomaviridae family; it causes 95% of nephropathy cases related to polyomavirus, with the other 5% caused by JC virus...
  26. Cayres Vallinoto I, Vallinoto A, Pena G, Azevedo V, Machado L, Ishak M, et al. JC virus/human immunodeficiency virus 1 co-infection in the Brazilian Amazonian region. Braz J Infect Dis. 2016;20:360-4 pubmed publisher
    JC virus (JCV) is a member of the Polyomaviridae family and is associated to a severe disease known as progressive multifocal leukoencephalopathy, PML, which is gradually increasing in incidence as an opportunistic infection among AIDS ..
  27. Pantazis P, Han Z, Chatterjee D, Wyche J. Water-insoluble camptothecin analogues as potential antiviral drugs. J Biomed Sci. 1999;6:1-7 pubmed
    ..These findings indicate that CPT analogues could be developed for use as potent drugs against DNA viruses. ..
  28. Belnap D, Grochulski W, Olson N, Baker T. Use of radial density plots to calibrate image magnification for frozen-hydrated specimens. Ultramicroscopy. 1993;48:347-58 pubmed
    ..35%-0.5%. Accurate scaling of a three-dimensional structure allows additional calibrations to be made with radial density plots computed from two- or three-dimensional data...
  29. Herrmann M, Oppenlander M, Pawlita M. Fast and high-affinity binding of B-lymphotropic papovavirus to human B-lymphoma cell lines. J Virol. 1995;69:6797-804 pubmed
    ..This indicates that the number of high-affinity receptors per cell is a key regulating factor for the LPV host range...
  30. Keef T, Twarock R, Elsawy K. Blueprints for viral capsids in the family of polyomaviridae. J Theor Biol. 2008;253:808-16 pubmed publisher
    ..1985. Virus Structure and Assembly. Jones and Bartlett, Boston, MA]. Especially, the family of Polyomaviridae, which contains cancer-causing viruses, falls out of the scope of this theory. In [Twarock, R., 2004...
  31. Mühlbach P, Pawlita M. A stable flank of unstable lymphotropic papovavirus integration sites is associated with a cellular S1 nuclease-sensitive sequence. Virology. 1992;186:65-73 pubmed
    ..The presence of this site may contribute to the stability of the flanking region...
  32. Moens U, Calvignac Spencer S, Lauber C, Ramqvist T, Feltkamp M, Daugherty M, et al. ICTV Virus Taxonomy Profile: Polyomaviridae. J Gen Virol. 2017;98:1159-1160 pubmed publisher
    The Polyomaviridae is a family of small, non-enveloped viruses with circular dsDNA genomes of approximately 5 kbp. The family includes four genera whose members have restricted host range, infecting mammals and birds...
  33. Munholland J, Kelly J, Hassell J, Wildeman A. Cell specificity of transcription regulation by papovavirus T antigens and DNA replication. EMBO J. 1992;11:177-84 pubmed
    ..Taken together, the data presented here suggest that papovaviruses may utilize permissive factors in transcription control mechanisms...
  34. Sock E, Enderich J, Wegner M. The J domain of papovaviral large tumor antigen is required for synergistic interaction with the POU-domain protein Tst-1/Oct6/SCIP. Mol Cell Biol. 1999;19:2455-64 pubmed
    ..Given the general role of J domains, we propose chaperone activity as the underlying mechanism for synergy between Tst-1/Oct6/SCIP and large T antigens...
  35. Helinski D, Clewell D. Circular DNA. Annu Rev Biochem. 1971;40:899-942 pubmed
  36. Takemoto K, Mullarkey M. Human papovavirus, BK strain: biological studies including antigenic relationship to simian virus 40. J Virol. 1973;12:625-31 pubmed
  37. Bastien C, Feunteun J. The hamster polyomavirus transforming properties. Oncogene. 1988;2:129-35 pubmed
    ..The viral genome is integrated in the host DNA and the early region is actively transcribed and translated...
  38. Bennett E, Naujokas M, Hassell J. Requirements for species-specific papovavirus DNA replication. J Virol. 1989;63:5371-85 pubmed
    ..These results suggest that species-specific permissive factors do not interact with the origin-auxiliary domains but, rather, with either the origin core or the large T antigen or with both components to effect DNA replication...
  39. Orefice G, Campanella G, Cicciarello S, Chirianni A, Borgia G, Rubino S, et al. Presence of papova-like viral particles in cerebrospinal fluid of AIDS patients with progressive multifocal leukoencephalopathy. An additional test for "in vivo" diagnosis. Acta Neurol (Napoli). 1993;15:328-32 pubmed
    ..Therefore, the CSF study by negative staining might be a useful test for an "in vivo" diagnosis of PML...
  40. Petry H, Goldmann C, Ast O, Lüke W. The use of virus-like particles for gene transfer. Curr Opin Mol Ther. 2003;5:524-8 pubmed
    ..This review will focus on studies performed with VLPs from members of the Papillomaviridae and Polyomaviridae families.
  41. Gray F, Geny C, Lescs M, Lionnet F, Brugieres P, Mikol J, et al. [AIDS-related progressive multifocal leukoencephalopathy limited to U fibers, responsible for subacute encephalopathy with normal CT scan findings]. Arch Anat Cytol Pathol. 1992;40:132-7 pubmed
    ..This case shows that papovavirus infection in AIDS patients may be responsible for a diffuse febrile encephalopathy with normal CT scan findings and a rapidly progressive course...
  42. Fattaey A, Lenz L, Consigli R. Production and characterization of monoclonal antibodies to budgerigar fledgling disease virus major capsid protein VP. Avian Dis. 1992;36:543-53 pubmed
    ..These MAbs were capable of detecting BFD virus protein in chicken embryonated cell-culture lysates by dot-blot analysis...
  43. Elo J, Hidvegi J, Bajtai A. Papova viruses and recurrent laryngeal papillomatosis. Acta Otolaryngol. 1995;115:322-5 pubmed
    ..It may reveal the inadequacies of removal of lesions and the need for adjuvant therapy. To make treatment more effective we have developed a therapeutic regimen that combines CO2 laser microsurgery with immunostimulants...
  44. Petterson M, Schaffner W. A purine-rich DNA sequence motif present in SV40 and lymphotropic papovavirus binds a lymphoid-specific factor and contributes to enhancer activity in lymphoid cells. Genes Dev. 1987;1:962-72 pubmed
    ..We suggest that such an arrangement reflects a diversification strategy of SV40 to maximize its chance of adaptation to various types of host cells...
  45. Chardonnet Y, Viac J, Schmitt D. [Malpighian epithelia infected by DNA viruses and Langerhans cells]. Pathol Biol (Paris). 1989;37:927-36 pubmed
  46. Padgett B, Walker D, ZuRhein G, Eckroade R, Dessel B. Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy. Lancet. 1971;1:1257-60 pubmed
  47. Marzec C, Day L. Pattern formation in icosahedral virus capsids: the papova viruses and Nudaurelia capensis beta virus. Biophys J. 1993;65:2559-77 pubmed
    ..In all cases examined so far, the MU orientations are correctly found...
  48. Symonds H, Chen J, Van Dyke T. Complex formation between the lymphotropic papovavirus large tumor antigen and the tumor suppressor protein p53. J Virol. 1991;65:5417-24 pubmed
    ..Sequential immunoprecipitation showed all detectable p53 to be of the PAb246+ class in each LPV-transformed cell line, suggesting that the stable p53 was indeed wild type...
  49. Chang T, Khalsa O, Wang H, Lee M, Schlegel R. Staurosporine resistance accompanies DNA tumor virus-induced immortalization and is independent of the expression and activities of ERK1, ERK2, cyclin A, cyclin-dependent kinase (cdk) 2, and cdk4. Cell Growth Differ. 1996;7:361-72 pubmed
  50. Lin M, Mutter G, Trivijisilp P, Boynton K, Sun D, Crum C. Patterns of allelic loss (LOH) in vulvar squamous carcinomas and adjacent noninvasive epithelia. Am J Pathol. 1998;152:1313-8 pubmed
    ..However, the divergent patterns of LOH observed imply that many genetic alterations in the adjacent vulvar epithelium are not directly related to the invasive carcinoma...
  51. Marshall J, Smith A, Cheng S. Monoclonal antibody specific for BK virus large-T antigen allows discrimination among the different papovaviral large-T antigens. Oncogene. 1991;6:1673-6 pubmed
    ..We show that when BK-T.1 is used in conjunction with preexisting monoclonal antibodies against SV40 large-T antigen, it is possible to identify the origin of papovavirus T antigens...
  52. Malkas L, Hickey R. Expression, purification, and characterization of DNA polymerases involved in papovavirus replication. Methods Enzymol. 1996;275:133-67 pubmed
    ..We believe that this information will enable us to develop an accurate view of the detailed processes mediating both pa..
  53. De Gascun C, Carr M. Human polyomavirus reactivation: disease pathogenesis and treatment approaches. Clin Dev Immunol. 2013;2013:373579 pubmed publisher
    ..The recent discoveries of eight new members of the Polyomaviridae family that are capable of infecting humans suggest that there are more to be discovered and raise the ..
  54. Katz R, Alappattu C, Glass J, Bruner J. Cerebrospinal fluid manifestations of the neurologic complications of human immunodeficiency virus infection. Acta Cytol. 1989;33:233-44 pubmed
    ..The CSF cytologic examination in HIV-infected patients with neurologic complications seems helpful in diagnosing cryptococcal meningitis and lymphoma, but less so for diagnosing toxoplasmosis...
  55. Varga E, Kiss M, Szabo K, Kemeny L. Detection of Merkel cell polyomavirus DNA in Merkel cell carcinomas. Br J Dermatol. 2009;161:930-2 pubmed publisher
    ..A new human polyomavirus, Merkel cell polyomavirus (MCV), was recently isolated from these tumours by applying digital transcriptome subtraction methodology...
  56. Hiraoka A, Ishikawa J, Kitayama H, Yamagami T, Teshima H, Nakamura H, et al. Hemorrhagic cystitis after bone marrow transplantation: importance of a thin sectioning technique on urinary sediments for diagnosis. Bone Marrow Transplant. 1991;7:107-11 pubmed
    ..These results suggest that a thin-sectioning technique on the cells of urinary sediments is important for the differential diagnosis between a viral-induced and non-viral hemorrhagic cystitis...
  57. Daniel R, Shah K, Madden D, Stagno S. Serological Investigation of the possibility of congenital transmission of papovavirus JC. Infect Immun. 1981;33:319-21 pubmed
    ..JC virus-specific immunoglobulin M was not demonstrated in umbilical cord sera of six infants born to mothers showing reactivation or in 300 additional umbilical cord sera from normal pregnancies...
  58. Mokhtarian F, Shah K. Pathogenesis of K papovavirus infection in athymic nude mice. Infect Immun. 1983;41:434-6 pubmed
    ..This protection was diminished by the depletion of B cells but not by the depletion of adherent cells from the primed spleen cells. B cell response is therefore important in the recovery of nude mice from K virus infection...
  59. Weidenheim K, Nelson S, Kure K, Harris C, Biempica L, Dickson D. Unusual patterns of Histoplasma capsulatum meningitis and progressive multifocal leukoencephalopathy in a patient with the acquired immunodeficiency virus. Hum Pathol. 1992;23:581-6 pubmed
    ..Each of these patterns of brain involvement is rare. As the incidence of AIDS increases and patients are treated aggressively, the frequency of unusual neuropathologic patterns of opportunistic infections may be expected to increase...
  60. Groen J, Broeders H, Spijkers I, Osterhaus A. Comparison of an enzyme-linked immunosorbent assay, an immunofluorescence assay and a hemagglutination inhibition assay for detection of antibodies to K-papovavirus in mice. Lab Anim Sci. 1989;39:21-4 pubmed
    ..The ELISA proved to be the most sensitive of the three assays and demonstrated K virus-specific antibodies as early as 3 days after infection...
  61. Keppler O, Herrmann M, Oppenlander M, Meschede W, Pawlita M. Regulation of susceptibility and cell surface receptor for the B-lymphotropic papovavirus by N glycosylation. J Virol. 1994;68:6933-9 pubmed
    ..We conclude that removal or modification of certain N-linked oligosaccharides in human B-lymphoma cells can enhance expression or functional activity of the sialylated LPV receptor...
  62. Borovoy M. The treatment of verrucae vulgaris with carbon dioxide laser surgery. Clin Podiatr Med Surg. 1987;4:799-807 pubmed
    ..The author describes the laser procedure in detail and provides guidelines for posttreatment management...
  63. Wu J, Simonette R, Nguyen H, Doan H, Rady P, Tyring S. Emerging differential roles of the pRb tumor suppressor in trichodysplasia spinulosa-associated polyomavirus and Merkel cell polyomavirus pathogeneses. J Clin Virol. 2016;76:40-3 pubmed publisher
    ..The observation that the pRb tumor suppressor is inactivated by TSPyV sT but not MCPyV sT provides further insights into the distinct pathobiological mechanisms of MCC and TS. ..
  64. Legoff J, Resche Rigon M, Bouquet J, Robin M, Naccache S, Mercier Delarue S, et al. The eukaryotic gut virome in hematopoietic stem cell transplantation: new clues in enteric graft-versus-host disease. Nat Med. 2017;23:1080-1085 pubmed publisher
    ..These results reveal a progressive expansion of vertebrate viral infections over time following HSCT, and they suggest an unexpected association of picobirnaviruses with early post-transplant GVHD. ..
  65. Eggers H. Experiments on antiviral activity of hand disinfectants. Some theoretical and practical considerations. Zentralbl Bakteriol. 1990;273:36-51 pubmed
    ..The load of rotavirus-contaminated hands, however, was substantially reduced by treatment with Desderman. A practical regimen can be proposed...
  66. Ramamoorthy S, Devaraj B, Miyai K, Luo L, Liu Y, Boland C, et al. John Cunningham virus T-antigen expression in anal carcinoma. Cancer. 2011;117:2379-85 pubmed publisher
    ..JCV T-antigen is present in brain, gastric, and colon malignancies, but has not been evaluated in anal cancers. The authors examined a cohort of anal cancers for JCV T-antigen and correlated this with clinicopathologic data...
  67. Ehrlich R. Modulation of antigen processing and presentation by persistent virus infections and in tumors. Hum Immunol. 1997;54:104-16 pubmed
    ..This review describes mechanisms used by viruses and in transformed cells for interference with antigen processing and presentation and addresses their significance for in vivo viral persistence and tumor progression...
  68. Keppler O, Peter M, Hinderlich S, Moldenhauer G, Stehling P, Schmitz I, et al. Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus. Glycobiology. 1999;9:557-69 pubmed
    ..To our knowledge, this is the first report demonstrating that differential sialylation in a clonal cell line may regulate the function of virus and signal-transducing receptors...
  69. Hall W, Farmer P, Takahashi H, Tanaka S, Furuta Y, Nagashima K. Pathological features of virus infections of the central nervous system (CNS) in the acquired immunodeficiency syndrome (AIDS). Acta Pathol Jpn. 1991;41:172-81 pubmed
    ..Mechanisms whereby HIV infection results in leukoencephalopathy and the possible contributing roles of the three opportunistic virus infections are discussed...
  70. Patt S, Zimmer C, Weigel K, Preuss M, Cervós Navarro J. [Brain biopsies in HIV-infected patients]. Verh Dtsch Ges Pathol. 1991;75:179-82 pubmed
    ..Conventional histology was not sufficiently decisive for toxoplasmosis, for some lymphomas and for PML. Stereotactic brain biopsy appears to be an effective method in the diagnosis of HIV-associated brain lesions...
  71. Cheng R, Olson N, Baker T. Cauliflower mosaic virus: a 420 subunit (T = 7), multilayer structure. Virology. 1992;186:655-68 pubmed
    ..1987, J. Cell Sci. (Suppl.) 7, 213-229). Remarkable agreement between the reconstructions of CaMV Cabb-B and CM1841 suggests that other strains of CaMV adopt the same basic structure...
  72. Tanaka Y, Tevethia M, Kalderon D, Smith A, Tevethia S. Clustering of antigenic sites recognized by cytotoxic T lymphocyte clones in the amino terminal half of SV40 T antigen. Virology. 1988;162:427-36 pubmed
    ..Our results indicate that the antigenic sites in the amino terminal half of SV40 T antigen are tightly clustered between amino acids 193 and 271 and most probably between 193 and 228...
  73. Orenstein J, Jannotta F. Human immunodeficiency virus and papovavirus infections in acquired immunodeficiency syndrome: an ultrastructural study of three cases. Hum Pathol. 1988;19:350-61 pubmed
    ..Transmission electron microscopy can be employed to reveal HIV and papovavirus infections not discernible at the light microscopic level and should be used as a diagnostic tool in HIV-related infections...
  74. Urbano P, Nali L, Bicalho C, Pierrotti L, David Neto E, Pannuti C, et al. New findings about trichodysplasia spinulosa-associated polyomavirus (TSPyV)--novel qPCR detects TSPyV-DNA in blood samples. Diagn Microbiol Infect Dis. 2016;84:123-4 pubmed publisher
    ..TSPyV-DNA was not detected in blood from healthy individuals, but 26.8% of kidney recipients presented TSPyV-DNA. This is the first report of TSPyV viremia. ..
  75. Calvignac Spencer S, Feltkamp M, Daugherty M, Moens U, Ramqvist T, Johne R, et al. A taxonomy update for the family Polyomaviridae. Arch Virol. 2016;161:1739-50 pubmed publisher
    ..To accommodate this fast-growing diversity, the International Committee on Taxonomy of Viruses (ICTV) Polyomaviridae Study Group designed a host- and sequence-based rationale for an updated taxonomy of the family Polyomaviridae...
  76. Nallaseth F, DePamphilis M. Papillomavirus contains cis-acting sequences that can suppress but not regulate origins of DNA replication. J Virol. 1994;68:3051-64 pubmed
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