nucleopolyhedrovirus

Summary

Summary: A genus of the family BACULOVIRIDAE, subfamily Eubaculovirinae, characterized by the formation of crystalline, polyhedral occlusion bodies in the host cell nucleus. The type species is Autographa californica nucleopolyhedrovirus.

Top Publications

  1. Liu C, Li Z, Wu W, Li L, Yuan M, Pan L, et al. Autographa californica multiple nucleopolyhedrovirus ac53 plays a role in nucleocapsid assembly. Virology. 2008;382:59-68 pubmed publisher
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) orf53 (ac53) is a highly conserved gene existing in all sequenced Lepidoptera and Hymenoptera baculoviruses, but its function remains unknown...
  2. Katsuma S, Nakanishi T, Shimada T. Bombyx mori nucleopolyhedrovirus FP25K is essential for maintaining a steady-state level of v-cath expression throughout the infection. Virus Res. 2009;140:155-60 pubmed publisher
    It has been previously reported that the fp25K product of Bombyx mori nucleopolyhedrovirus (BmNPV) is required for post-mortem host degradation, but the mechanism by which it regulates host degradation is still unknown...
  3. Fang M, Nie Y, Theilmann D. Deletion of the AcMNPV core gene ac109 results in budded virions that are non-infectious. Virology. 2009;389:66-74 pubmed publisher
    Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ac109 is a core gene and its function in the virus life cycle is unknown...
  4. Singh J, Singh C, Bhavani A, Nagaraju J. Discovering microRNAs from Bombyx mori nucleopolyhedrosis virus. Virology. 2010;407:120-8 pubmed publisher
  5. Katsuma S, Tsuchida A, Matsuda Imai N, Kang W, Shimada T. Role of the ubiquitin-proteasome system in Bombyx mori nucleopolyhedrovirus infection. J Gen Virol. 2011;92:699-705 pubmed publisher
    ..Furthermore, Western blots also showed that v-UBI was not required for degradation of IE2, which is known as a target viral protein of the ubiquitin-proteasome system. ..
  6. Salem T, Zhang F, Xie Y, Thiem S. Comprehensive analysis of host gene expression in Autographa californica nucleopolyhedrovirus-infected Spodoptera frugiperda cells. Virology. 2011;412:167-78 pubmed publisher
    Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) is the best-studied baculovirus and most commonly used virus vector for baculovirus expression vector systems...
  7. Katsuma S, Horie S, Shimada T. The fibroblast growth factor homolog of Bombyx mori nucleopolyhedrovirus enhances systemic virus propagation in B. mori larvae. Virus Res. 2008;137:80-5 pubmed publisher
    ..Recently, we generated a Bombyx mori nucleopolyhedrovirus (BmNPV) mutant lacking functional vfgf and found that BmNPV vfgf contributes to virus virulence in B...
  8. Jiang L, Wang G, Cheng T, Yang Q, Jin S, Lu G, et al. Resistance to Bombyx mori nucleopolyhedrovirus via overexpression of an endogenous antiviral gene in transgenic silkworms. Arch Virol. 2012;157:1323-8 pubmed publisher
    ..mori nucleopolyhedrovirus (BmNPV)...
  9. Hori T, Kiuchi T, Shimada T, Nagata M, Katsuma S. Silkworm plasmatocytes are more resistant than other hemocyte morphotypes to Bombyx mori nucleopolyhedrovirus infection. J Invertebr Pathol. 2013;112:102-4 pubmed publisher
    ..In this study, a Bombyx mori nucleopolyhedrovirus (BmNPV) derivative possessing a Drosophila hsp70 promoter-driven green fluorescent protein (GFP) gene was ..

More Information

Publications102 found, 100 shown here

  1. Kato T, Manoha S, Tanaka S, Park E. High-titer preparation of Bombyx mori nucleopolyhedrovirus (BmNPV) displaying recombinant protein in silkworm larvae by size exclusion chromatography and its characterization. BMC Biotechnol. 2009;9:55 pubmed publisher
    ..In this study, we tried to produce and purify the recombinant Bombyx mori nucleopolyhedrovirus (rBmNPV-hPRR) that displayed human (pro)renin receptor (hPRR) connected with FLAG peptide sequence on its ..
  2. Chen H, Li G, Huang G, Chen K, Yao Q, Guo Z. Characterization of ORF29 of Bombyx mori nucleopolyhedrovirus. Acta Virol. 2010;54:275-80 pubmed
    ORF 29 of Bombyx mori nucleopolyhedrovirus (BmNPV ORF29), a conserved gene among all the lepidopteran baculoviruses, was subjected to analysis of sequence and transcription/translation in the insect BmN cells in vitro...
  3. Yuan M, Huang Z, Wei D, Hu Z, Yang K, Pang Y. Identification of Autographa californica nucleopolyhedrovirus ac93 as a core gene and its requirement for intranuclear microvesicle formation and nuclear egress of nucleocapsids. J Virol. 2011;85:11664-74 pubmed publisher
    Autographa californica nucleopolyhedrovirus (AcMNPV) orf93 (ac93) is a highly conserved uncharacterized gene that is found in all of the sequenced baculovirus genomes except for Culex nigripalpus NPV...
  4. Virto C, Zarate C, Lopez Ferber M, Murillo R, Caballero P, Williams T. Gender-mediated differences in vertical transmission of a nucleopolyhedrovirus. PLoS ONE. 2013;8:e70932 pubmed publisher
    ..Vertical transmission of Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) is common in natural populations of S. exigua...
  5. Nai Y, Wu C, Wang T, Chen Y, Lau W, Lo C, et al. Genomic sequencing and analyses of Lymantria xylina multiple nucleopolyhedrovirus. BMC Genomics. 2010;11:116 pubmed publisher
    ..LyxyMNPV (L. xylina multiple nucleopolyhedrovirus) is highly virulent to the casuarina moth and has been investigated as a possible biopesticide for ..
  6. Gandhi K, Ohkawa T, Welch M, Volkman L. Nuclear localization of actin requires AC102 in Autographa californica multiple nucleopolyhedrovirus-infected cells. J Gen Virol. 2012;93:1795-803 pubmed publisher
    Autographa californica multiple nucleopolyhedrovirus requires nuclear actin for progeny virus production and thereby encodes viral products that ensure actin's translocation to and retention within the nucleus...
  7. Moreno Habel D, Biglang awa I, Dulce A, Luu D, Garcia P, Weers P, et al. Inactivation of the budded virus of Autographa californica M nucleopolyhedrovirus by gloverin. J Invertebr Pathol. 2012;110:92-101 pubmed publisher
    ..ni systemically infected with the baculovirus Autographa californica M nucleopolyhedrovirus (AcMNPV). Two gloverin genes were cloned using RNA isolated from the hemocytes of T...
  8. Grein T, Michalsky R, Vega López M, Czermak P. Purification of a recombinant baculovirus of Autographa californica M nucleopolyhedrovirus by ion exchange membrane chromatography. J Virol Methods. 2012;183:117-24 pubmed publisher
    ..work the stability and ion exchange membrane chromatography of a recombinant of Autographa californica M nucleopolyhedrovirus is studied...
  9. Laakkonen J, Mäkelä A, Kakkonen E, Turkki P, Kukkonen S, Peranen J, et al. Clathrin-independent entry of baculovirus triggers uptake of E. coli in non-phagocytic human cells. PLoS ONE. 2009;4:e5093 pubmed publisher
    The prototype baculovirus, Autographa californica multiple nucleopolyhedrovirus, an insect pathogen, holds great potential as a gene therapy vector...
  10. Carpes M, Nunes J, Sampaio T, Castro M, Zanotto P, Ribeiro B. Molecular analysis of a mutant Anticarsia gemmatalis multiple nucleopolyhedrovirus (AgMNPV) shows an interruption of an inhibitor of apoptosis gene (iap-3) by a new class-II piggyBac-related insect transposon. Insect Mol Biol. 2009;18:747-57 pubmed publisher
    ..transposable element (TE) was found in the genome of a mutant Anticarsia gemmatalis multiple nucleopolyhedrovirus interrupting an inhibitor of apoptosis gene...
  11. Harrison R, Sparks W, Bonning B. Autographa californica multiple nucleopolyhedrovirus ODV-E56 envelope protein is required for oral infectivity and can be substituted functionally by Rachiplusia ou multiple nucleopolyhedrovirus ODV-E56. J Gen Virol. 2010;91:1173-82 pubmed publisher
    The Autographa californica multiple nucleopolyhedrovirus (AcMNPV) odv-e56 gene encodes an occlusion-derived virus (ODV)-specific envelope protein, ODV-E56...
  12. Xue J, Qiao N, Zhang W, Cheng R, Zhang X, Bao Y, et al. Dynamic interactions between Bombyx mori nucleopolyhedrovirus and its host cells revealed by transcriptome analysis. J Virol. 2012;86:7345-59 pubmed publisher
    ..To determine the host response to Bombyx mori nucleopolyhedrovirus infection and the dynamic interaction between the virus and its host, eight digital gene expression ..
  13. Chen Y, Lin X, Yi Y, Lu Y, Zhang Z. Construction and application of a baculovirus genomic library. Z Naturforsch C. 2009;64:574-80 pubmed
    A random genomic library of the baculovirus Bombyx mori nucleopolyhedrovirus (BmNPV) was constructed and viral factors were identified by screening the regulator(s) for helicase gene expression...
  14. Lyupina Y, Abaturova S, Erokhov P, Orlova O, Beljelarskaya S, Mikhailov V. Proteotoxic stress induced by Autographa californica nucleopolyhedrovirus infection of Spodoptera frugiperda Sf9 cells. Virology. 2013;436:49-58 pubmed publisher
    ..This result suggests that lysosomes may assist in protection against proteotoxicity caused by baculoviruses absorbing the ubiquitinated proteins...
  15. Chaivisuthangkura P, Tawilert C, Tejangkura T, Rukpratanporn S, Longyant S, Sithigorngul W, et al. Molecular isolation and characterization of a novel occlusion body protein gene from Penaeus monodon nucleopolyhedrovirus. Virology. 2008;381:261-7 pubmed publisher
    The full-length of the occlusion body (OB) protein gene of Penaeus monodon nucleopolyhedrovirus (PemoNPV) was successfully isolated...
  16. Chen Y, Zhong S, Fei Z, Hashimoto Y, XIANG J, Zhang S, et al. The transcriptome of the baculovirus Autographa californica multiple nucleopolyhedrovirus in Trichoplusia ni cells. J Virol. 2013;87:6391-405 pubmed publisher
    ..Combined, these data provide an emerging global picture of the organization and regulation of AcMNPV transcription through the infection cycle. ..
  17. Guo Z, Wang D, Yao Q, Chen K, Zhang C. Identification of a novel functional nuclear localization signal in the protein encoded by open reading frame 47 of Bombyx mori nucleopolyhedrovirus. Arch Virol. 2010;155:1943-50 pubmed publisher
    BM47 is encoded by open reading frame 47 of Bombyx mori nucleopolyhedrovirus (BmNPV). BM47 was localized in the nucleus of BmNPV-infected cells...
  18. Katsuma S, Kang W, Shin I T, Ohishi K, Kadota K, Kohara Y, et al. Mass identification of transcriptional units expressed from the Bombyx mori nucleopolyhedrovirus genome. J Gen Virol. 2011;92:200-3 pubmed publisher
    In order to identify the transcriptional units expressed from an entire nucleopolyhedrovirus (NPV) genome during infection, we constructed a full-length-enriched cDNA library from Bombyx mori NPV (BmNPV)-infected BmN cells...
  19. Song J, Wang R, Deng F, Wang H, Hu Z. Functional studies of per os infectivity factors of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus. J Gen Virol. 2008;89:2331-8 pubmed publisher
    ..investigation on the four per os infectivity factors (PIFs) of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus (HearNPV) was conducted in this study...
  20. Wu W, Liang H, Kan J, Liu C, Yuan M, Liang C, et al. Autographa californica multiple nucleopolyhedrovirus 38K is a novel nucleocapsid protein that interacts with VP1054, VP39, VP80, and itself. J Virol. 2008;82:12356-64 pubmed publisher
    It has been shown that the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) 38K (ac98) is required for nucleocapsid assembly. However, the exact role of 38K in nucleocapsid assembly remains unknown...
  21. Slack J, Lawrence S, Krell P, Arif B. A soluble form of P74 can act as a per os infectivity factor to the Autographa californica multiple nucleopolyhedrovirus. J Gen Virol. 2010;91:915-8 pubmed publisher
    ..The Autographa californica multicapsid nucleopolyhedrovirus P74 protein is an ODV envelope protein that is essential for ODVs to be infectious...
  22. Georgievska L, Hoover K, van der Werf W, Muñoz D, Caballero P, Cory J, et al. Dose dependency of time to death in single and mixed infections with a wildtype and egt deletion strain of Helicoverpa armigera nucleopolyhedrovirus. J Invertebr Pathol. 2010;104:44-50 pubmed publisher
    ..The number of occlusion bodies produced per larva increased with time to death and decreased with virus dose, but no significant differences among virus types were found. ..
  23. Tian C, Tang X, Xu H, Ge J, Miao Y, Zhang C. Bombyx mori nucleopolyhedrovirus ORF51 encodes a budded virus envelope associated protein. Virus Genes. 2009;38:171-7 pubmed publisher
    Bombyx mori nucleopolyhedrovirus (BmNPV) ORF 51 (Bm51) is a gene present in many lepidopteran NPVs, but its function is unknown. In this study, Bm51 was characterized. Transcripts of Bm51 were detected from 4...
  24. Sparks W, Rohlfing A, Bonning B. A peptide with similarity to baculovirus ODV-E66 binds the gut epithelium of Heliothis virescens and impedes infection with Autographa californica multiple nucleopolyhedrovirus. J Gen Virol. 2011;92:1051-60 pubmed publisher
    ..HV2, and two peptides (AcE66A and AcE66B) derived from similar sequences of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) ODV-E66, bound to unfixed cryosections of whole midgut tissues. AcE66A, but not HV1, bound to H...
  25. Zhou J, Li X, De Eknamkul W, Suraporn S, Xu J. Identification of a new Bombyx mori nucleopolyhedrovirus and analysis of its bro gene family. Virus Genes. 2012;44:539-47 pubmed publisher
    The highly pathogenic Bombyx mori nucleopolyhedrovirus (BmNPV) has caused severe damages to sericulture in many countries, and the relationship between the pathogenicity of various BmNPV strains and their geographical evolution has been ..
  26. Zhu S, Yi J, Shen W, Wang L, He H, Wang Y, et al. Genomic sequence, organization and characteristics of a new nucleopolyhedrovirus isolated from Clanis bilineata larva. BMC Genomics. 2009;10:91 pubmed publisher
    ..In this study, the complete genome of Clanis bilineata nucleopolyhedrovirus (ClbiNPV) has been sequenced and analyzed in order to understand this virus better...
  27. Peng K, van Oers M, Hu Z, van Lent J, Vlak J. Baculovirus per os infectivity factors form a complex on the surface of occlusion-derived virus. J Virol. 2010;84:9497-504 pubmed publisher
    ..stable complex on the surface of ODV particles of the baculovirus Autographa californica multinucleocapsid nucleopolyhedrovirus (AcMNPV). The complex could withstand 2% SDS-5% beta-mercaptoethanol with heating at 50 degrees C for 5 min...
  28. Wei W, Gai Z, Ai H, Wu W, Yang Y, Peng J, et al. Baculovirus infection triggers a shift from amino acid starvation-induced autophagy to apoptosis. PLoS ONE. 2012;7:e37457 pubmed publisher
    ..In the present study, we investigated the effects of the Autographa californica nucleopolyhedrovirus (AcMNPV) infection on autophagy in SL-HP cell line from Spodoptera litura induced under amino acid ..
  29. Graham R, Grzywacz D, Mushobozi W, Wilson K. Wolbachia in a major African crop pest increases susceptibility to viral disease rather than protects. Ecol Lett. 2012;15:993-1000 pubmed publisher
    ..This finding potentially has implications for the biological control of other insect crop pests. ..
  30. Shen H, Chen K, Yao Q, Yu W, Pan Y, Huo J, et al. Characterization of Bombyx mori nucleopolyhedrovirus orf74, a novel gene involved in virulence of virus. Virus Genes. 2009;38:487-94 pubmed publisher
    orf74 of Bombyx mori nucleopolyhedrovirus (BmNPV) is a homologue of uncharacterized orf91 of Autographa californica multicapsid NPV, predicted to encode a protein of 17.3 kDa...
  31. Wu C, Chen Y, Lin C, Hsu C, Wang C, Lo C. A new cell line (NTU-SE) from pupal tissues of the beet armyworm, Spodoptera exigua (Lepidoptera: Noctuidae), is highly susceptible to S. exigua multiple nucleopolyhedrovirus (SeMNPV) and Autographa californica MNPV (AcMNPV). J Invertebr Pathol. 2012;111:143-51 pubmed publisher
    ..litura larvae. The NTU-SE cell line is highly susceptible to S. exigua multiple nucleopolyhedrovirus (SeMNPV) and Autographa californica MNPV (AcMNPV)...
  32. Harrison R. Genomic sequence analysis of the Illinois strain of the Agrotis ipsilon multiple nucleopolyhedrovirus. Virus Genes. 2009;38:155-70 pubmed publisher
    The Agrotis ipsilon multiple nucleopolyhedrovirus (AgipMNPV) is a group II nucleopolyhedrovirus (NPV) from the black cutworm, A. ipsilon, with potential as a biopesticide to control infestations of cutworm larvae...
  33. Ribeiro B, Generino A, Acacio C, Kalapothakis E, B o S. Characterization of a new Autographa californica multiple nucleopolyhedrovirus (AcMNPV) polyhedra mutant. Virus Res. 2009;140:1-7 pubmed publisher
    ..The phenotype of this recombinant virus was the same as the mutant one, confirming that this single mutation alone was responsible for the mutant phenotype...
  34. Hashimoto Y, Zhang S, Blissard G. Ao38, a new cell line from eggs of the black witch moth, Ascalapha odorata (Lepidoptera: Noctuidae), is permissive for AcMNPV infection and produces high levels of recombinant proteins. BMC Biotechnol. 2010;10:50 pubmed publisher
    ..The insect cell line is a critical component in the production of recombinant proteins in the baculovirus expression system and new cell lines hold the promise of increasing both quantity and quality of protein production...
  35. Burand J, Kim W, Welch A, Elkinton J. Identification of a nucleopolyhedrovirus in winter moth populations from Massachusetts. J Invertebr Pathol. 2011;108:217-9 pubmed publisher
    ..We identified O. brumata nucleopolyhedrovirus (OpbuNPV) in winter moth larvae collected from field sites in Massachusetts by using PCR to amplify a 482 ..
  36. Tang X, Xiao Q, Ma X, Zhu Z, Zhang C. Morphology and genome of Euproctis pseudoconspersa nucleopolyhedrovirus. Virus Genes. 2009;38:495-506 pubmed publisher
    ..Gene parity plots, percent identities of gene homologues and phylogenetic analysis all suggested that EupsNPV is most closely related to EcobNPV in Group II NPV, although its genomic organization was highly distinct...
  37. Shirata N, Ikeda M, Kobayashi M. Identification of a Hyphantria cunea nucleopolyhedrovirus (NPV) gene that is involved in global protein synthesis shutdown and restricted Bombyx mori NPV multiplication in a B. mori cell line. Virology. 2010;398:149-57 pubmed publisher
    We previously demonstrated that Bombyx mori nucleopolyhedrovirus (BmNPV) multiplication is restricted in permissive BmN-4 cells upon coinfection with Hyphantria cunea NPV (HycuNPV)...
  38. Xu Y, Ye Z, Niu C, Bao Y, Wang W, Shen W, et al. Comparative analysis of the genomes of Bombyx mandarina and Bombyx mori nucleopolyhedroviruses. J Microbiol. 2010;48:102-10 pubmed publisher
    The Bombyx mandarina nucleopolyhedrovirus (BomaNPV) S1 strain can infect the silkworm, Bombyx mori, but is significantly less virulent than B. mori nucleopolyhedrovirus (BmNPV) T3 strain...
  39. Kamiya K, Kobayashi J, Yoshimura T, Tsumoto K. Confocal microscopic observation of fusion between baculovirus budded virus envelopes and single giant unilamellar vesicles. Biochim Biophys Acta. 2010;1798:1625-31 pubmed publisher
    ..between giant unilamellar vesicles (GUVs) and budded viruses (BVs) of baculovirus (Autographa californica nucleopolyhedrovirus), the envelopes of which have been labeled with the fluorescent dye Alexa Fluor 488...
  40. Elvira S, Williams T, Caballero P. Juvenile hormone analog technology: effects on larval cannibalism and the production of Spodoptera exigua (Lepidoptera: Noctuidae) nucleopolyhedrovirus. J Econ Entomol. 2010;103:577-82 pubmed
    The production of a multiple nucleopolyhedrovirus (SeMNPV) of the beet armyworm, Spodoptera exigua (Hübner) (Lepidoptera: Noctuidae), has been markedly increased by using juvenile hormone analog (JHA) technology to generate a ..
  41. Cabodevilla O, Villar E, Virto C, Murillo R, Williams T, Caballero P. Intra- and intergenerational persistence of an insect nucleopolyhedrovirus: adverse effects of sublethal disease on host development, reproduction, and susceptibility to superinfection. Appl Environ Microbiol. 2011;77:2954-60 pubmed publisher
    Sublethal infections by Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) are common in field populations of the beet armyworm (S. exigua, Hübner) in the Almerian horticultural region of Spain...
  42. Simón O, Williams T, Lopez Ferber M, Caballero P. Deletion of egt is responsible for the fast-killing phenotype of natural deletion genotypes in a Spodoptera frugiperda multiple nucleopolyhedrovirus population. J Invertebr Pathol. 2012;111:260-3 pubmed publisher
    A Nicaraguan population of Spodoptera frugiperda multiple nucleopolyhedrovirus, SfMNPV-NIC, includes fast-killing genotypes with deletions in the egt region...
  43. Xiao W, Yang Y, Weng Q, Lin T, Yuan M, Yang K, et al. The role of the PI3K-Akt signal transduction pathway in Autographa californica multiple nucleopolyhedrovirus infection of Spodoptera frugiperda cells. Virology. 2009;391:83-9 pubmed publisher
    ..In the present study, we demonstrate that infection of Sf9 cells with Autographa californica multiple nucleopolyhedrovirus (AcMNPV) elevated cellular Akt phosphorylation at 1 h post-infection...
  44. Yu M, Carstens E. Characterization of an Autographa californica multiple nucleopolyhedrovirus mutant lacking the ac39(p43) gene. Virus Res. 2011;155:300-6 pubmed publisher
    Open reading frame 39 [orf39(p43)] of Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) is present in 10 isolates of the Alphabaculovirus genus...
  45. Kang L, Shi H, Liu X, Zhang C, Yao Q, Wang Y, et al. Arginine kinase is highly expressed in a resistant strain of silkworm (Bombyx mori, Lepidoptera): Implication of its role in resistance to Bombyx mori nucleopolyhedrovirus. Comp Biochem Physiol B Biochem Mol Biol. 2011;158:230-4 pubmed publisher
    ..has been indentified differentially expressed in the midguts of Bombyx mori strain NB which is resistant to nucleopolyhedrovirus (BmNPV), strain 306 which is susceptible to NPV and a near isogenic line BC(8) with similar genetic ..
  46. Luo S, Zhang Y, Xu X, Westenberg M, Vlak J, Wang H, et al. Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, HA100, affects oral infectivity in vivo but not virus replication in vitro. J Gen Virol. 2011;92:1324-31 pubmed publisher
    ORF100 (ha100) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV) has been reported as one of the unique genes of group II alphabaculoviruses encoding a protein located in the occlusion-derived virus (ODV) envelope and nucleocapsid...
  47. Ravikumar G, Raje Urs S, Vijaya Prakash N, Rao C, Vardhana K. Development of a multiplex polymerase chain reaction for the simultaneous detection of microsporidians, nucleopolyhedrovirus, and densovirus infecting silkworms. J Invertebr Pathol. 2011;107:193-7 pubmed publisher
    ..novel PCR-based assay for individual and simultaneous detection of three major pathogens (microsporidians, nucleopolyhedrovirus (NPV) and densovirus (DNV)) infecting the silkworm, Bombyx mori...
  48. Jayachandran B, Hussain M, Asgari S. RNA interference as a cellular defense mechanism against the DNA virus baculovirus. J Virol. 2012;86:13729-34 pubmed publisher
    ..small reads of ?20 nucleotides from Helicoverpa armigera larvae infected with Helicoverpa armigera single nucleopolyhedrovirus (HaSNPV) were mapped to certain open reading frames in the viral genome (hot spots) that are mostly ..
  49. Bae S, Kim H, Lee J, Choi J, Shin T, Koo H, et al. Hyper-enhanced production of foreign recombinant protein by fusion with the partial polyhedrin of nucleopolyhedrovirus. PLoS ONE. 2013;8:e60835 pubmed publisher
    ..This study suggests a new option for higher expression of useful foreign recombinant protein by using the partial polyhedrin in baculovirus...
  50. Iizuka M, Tomita M, Shimizu K, Kikuchi Y, Yoshizato K. Translational enhancement of recombinant protein synthesis in transgenic silkworms by a 5'-untranslated region of polyhedrin gene of Bombyx mori Nucleopolyhedrovirus. J Biosci Bioeng. 2008;105:595-603 pubmed publisher
    ..In this study, we examined whether the 5'-untranslated region (5'-UTR) of the polyhedrin gene (pol) of nucleopolyhedrovirus (NPV) has a translational enhancer activity in the r-protein expression by middle silk gland (MSG) cells of ..
  51. Peng K, Wu M, Deng F, Song J, Dong C, Wang H, et al. Identification of protein-protein interactions of the occlusion-derived virus-associated proteins of Helicoverpa armigera nucleopolyhedrovirus. J Gen Virol. 2010;91:659-70 pubmed publisher
    ..interactions among the components of the occlusion-derived virus (ODV) of Helicoverpa armigera nucleopolyhedrovirus (HearNPV), a group II alphabaculovirus in the family Baculoviridae...
  52. McNeil J, Cox Foster D, Gardner M, Slavicek J, Thiem S, Hoover K. Pathogenesis of Lymantria dispar multiple nucleopolyhedrovirus in L. dispar and mechanisms of developmental resistance. J Gen Virol. 2010;91:1590-600 pubmed publisher
    Lymantria dispar has a long historical association with the baculovirus Lymantria dispar multiple nucleopolyhedrovirus (LdMNPV), which is one of the primary population regulators of L. dispar in the field...
  53. Rowley D, Farrar R, Blackburn M, Harrison R. Genetic and biological variation among nucleopolyhedrovirus isolates from the fall armyworm, Spodoptera frugiperda (Lepidoptera: Noctuidae). Virus Genes. 2010;40:458-68 pubmed publisher
    A PCR-based method was used to identify and distinguish among 40 uncharacterized nucleopolyhedrovirus (NPV) isolates from larvae of the moth Spodoptera frugiperda that were part of an insect virus collection...
  54. Yamada H, Shibuya M, Kobayashi M, Ikeda M. Identification of a novel apoptosis suppressor gene from the baculovirus Lymantria dispar multicapsid nucleopolyhedrovirus. J Virol. 2011;85:5237-42 pubmed publisher
    ..Apsup is expressed in LdMNPV-infected Ld652Y cells late in infection, and RNA interference-mediated apsup ablation induces apoptosis of LdMNPV-infected Ld652Y cells...
  55. Harrison R, Popham H, Breitenbach J, Rowley D. Genetic variation and virulence of Autographa californica multiple nucleopolyhedrovirus and Trichoplusia ni single nucleopolyhedrovirus isolates. J Invertebr Pathol. 2012;110:33-47 pubmed publisher
    To determine the genetic diversity within the baculovirus species Autographa calfornica multiple nucleopolyhedrovirus (AcMNPV; Baculoviridae: Alphabaculovirus), a PCR-based method was used to identify and classify baculoviruses found in ..
  56. Kato T, Suzuki F, Park E. Display of the human (pro)renin receptor on Bombyx mori nucleopolyhedrovirus (BmNPV) particles using Bm cells. J Biosci Bioeng. 2012;114:564-9 pubmed publisher
    The human (pro)renin receptor (hPRR) was displayed on the surface of Bombyx mori nucleopolyhedrovirus (BmNPV) with and without fusion to glycoprotein 64 (GP64) of the BmNPV...
  57. Vieira C, Tuelher E, Valicente F, Wolff J. Characterization of a Spodoptera frugiperda multiple nucleopolyhedrovirus isolate that does not liquefy the integument of infected larvae. J Invertebr Pathol. 2012;111:189-92 pubmed publisher
    Here we report the characterization of a Spodoptera frugiperda multiple nucleopolyhedrovirus isolate, named SfMNPV-6nd, that does not cause the liquefaction of the host integument...
  58. Dong S, Wang M, Qiu Z, Deng F, Vlak J, Hu Z, et al. Autographa californica multicapsid nucleopolyhedrovirus efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH. J Virol. 2010;84:5351-9 pubmed publisher
    The budded virus (BV) of the Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) infects insect cells and transduces mammalian cells mainly through the endocytosis pathway...
  59. Giri L, Li H, Sandgren D, FEISS M, Roller R, Bonning B, et al. Removal of transposon target sites from the Autographa californica multiple nucleopolyhedrovirus fp25k gene delays, but does not prevent, accumulation of the few polyhedra phenotype. J Gen Virol. 2010;91:3053-64 pubmed publisher
    Low-cost, large-scale production of the baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) using continuous insect cell culture is seriously hindered by the accumulation of AcMNPV mutants...
  60. Wu W, Passarelli A. Autographa californica multiple nucleopolyhedrovirus Ac92 (ORF92, P33) is required for budded virus production and multiply enveloped occlusion-derived virus formation. J Virol. 2010;84:12351-61 pubmed publisher
    The Autographa californica multiple nucleopolyhedrovirus orf92 (p33), ac92, is one of 31 genes carried in all sequenced baculovirus genomes, thus suggesting an essential function...
  61. Jiang J, Zeng A, Ji X, Wan N, Chen X. Combined effect of nucleopolyhedrovirus and Microplitis pallidipes for the control of the beet armyworm, Spodoptera exigua. Pest Manag Sci. 2011;67:705-13 pubmed publisher
    b>Nucleopolyhedrovirus (SeNPV) and Microplitis pallidipes are important biological control agents of Spodoptera exigua populations...
  62. Nie Y, Fang M, Erlandson M, Theilmann D. Analysis of the autographa californica multiple nucleopolyhedrovirus overlapping gene pair lef3 and ac68 reveals that AC68 is a per os infectivity factor and that LEF3 is critical, but not essential, for virus replication. J Virol. 2012;86:3985-94 pubmed publisher
    Autographa californica multiple nucleopolyhedrovirus ac68 is a core gene that overlaps lef3 which encodes the single-stranded DNA binding protein...
  63. Shen S, Gan Y, Wang M, Hu Z, Wang H, Deng F. Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro. J Gen Virol. 2012;93:2705-11 pubmed publisher
    The envelope fusion proteins of baculoviruses, glycoprotein GP64 from group I nucleopolyhedrovirus (NPV) or the F protein from group II NPV and granulovirus, are essential for baculovirus morphogenesis and infectivity...
  64. Elderd B, Dushoff J, Dwyer G. Host-pathogen interactions, insect outbreaks, and natural selection for disease resistance. Am Nat. 2008;172:829-42 pubmed publisher
    ..We measured heterogeneity among gypsy moth larvae in their risk of infection with a nucleopolyhedrovirus, which is effectively heterogeneity in the pathogen's attack rate...
  65. Terenius O, Popham H, Shelby K. Bacterial, but not baculoviral infections stimulate Hemolin expression in noctuid moths. Dev Comp Immunol. 2009;33:1176-85 pubmed publisher
    ..Heliothis virescens), have a 1000-fold difference in sensitivity to Autographa californica multiple nucleopolyhedrovirus (AcMNPV) infection...
  66. Sun J, Yao L, Yao N, Xu H, Jin P, Kan Y. Production of recombinant Bombyx mori nucleopolyhedrovirus in silkworm by intrahaemocoelic injection with invasive diaminopimelate auxotrophic Escherichia coli containing BmNPV-Bacmid. Biotechnol Appl Biochem. 2010;57:117-25 pubmed publisher
    ..elaborates a cost-effective and transfectant-free method for generating recombinant Bombyx mori (silkworm) nucleopolyhedrovirus in silkworm larvae and pupae by injecting invasive Escherichia coli carrying BmBacmid [BmNPV (B...
  67. Behle R, Popham H. Laboratory and field evaluations of the efficacy of a fast-killing baculovirus isolate from Spodoptera frugiperda. J Invertebr Pathol. 2012;109:194-200 pubmed publisher
    ..evaluated for a fast-killing isolate (3AP2) and a wild-type isolate (Sf3) of Spodoptera frugiperda multiple nucleopolyhedrovirus (SfMNPV)...
  68. Choi J, Roh J, Wang Y, Zhen Z, Tao X, Lee J, et al. Analysis of genes expression of Spodoptera exigua larvae upon AcMNPV infection. PLoS ONE. 2012;7:e42462 pubmed publisher
    The impact of Autographa californica multicapsid nucleopolyhedrovirus (AcMNPV) infection on host gene expression in Spodoptera exigua 4th instar larvae was investigated through the use of 454 sequencing-based RNA-seq of cDNA libraries ..
  69. Ponnuvel K, Nithya K, Sirigineedi S, Awasthi A, Yamakawa M. In vitro antiviral activity of an alkaline trypsin from the digestive juice of Bombyx mori larvae against nucleopolyhedrovirus. Arch Insect Biochem Physiol. 2012;81:90-104 pubmed publisher
    ..from the digestive juice of Bombyx mori larvae indicated strong antiviral activity against Bombyx mori nucleopolyhedrovirus (BmNPV) under in vitro conditions...
  70. Chen Y, Wu C, Lee S, Wu Y, Lo C, Tsai M, et al. Genomic and host range studies of Maruca vitrata nucleopolyhedrovirus. J Gen Virol. 2008;89:2315-30 pubmed publisher
    The complete genome of the Maruca vitrata nucleopolyhedrovirus (MaviNPV) isolated from the legume pod borer, Maruca vitrata (Lepidoptera: Pyralidae), was sequenced...
  71. Liu X, Chen K, Cai K, Yao Q. Determination of protein composition and host-derived proteins of Bombyx mori nucleopolyhedrovirus by 2-dimensional electrophoresis and mass spectrometry. Intervirology. 2008;51:369-76 pubmed publisher
    ..The virion contains proteins essential for host-range determination and initiation of infection. Determination of protein composition of the occlusion-derived virus (ODV) will help us to understand this virion's infection mechanism...
  72. de Jong J, Arif B, Theilmann D, Krell P. Autographa californica multiple nucleopolyhedrovirus me53 (ac140) is a nonessential gene required for efficient budded-virus production. J Virol. 2009;83:7440-8 pubmed publisher
    ..Together, these results indicate that me53, although not essential for viral replication, is required for efficient BV production...
  73. Redman E, Wilson K, Grzywacz D, Cory J. High levels of genetic diversity in Spodoptera exempta NPV from Tanzania. J Invertebr Pathol. 2010;105:190-3 pubmed publisher
    The African armyworm, Spodoptera exempta, is a major pest in sub-Saharan Africa. A nucleopolyhedrovirus (NPV) is often recorded in later population outbreaks and can cause very high levels of mortality...
  74. Ohkawa T, Volkman L, Welch M. Actin-based motility drives baculovirus transit to the nucleus and cell surface. J Cell Biol. 2010;190:187-95 pubmed publisher
    ..In this study, we show that nucleocapsids of the baculovirus Autographa californica multiple nucleopolyhedrovirus undergo intracellular motility driven by actin polymerization...
  75. Rowley D, Popham H, Harrison R. Genetic variation and virulence of nucleopolyhedroviruses isolated worldwide from the heliothine pests Helicoverpa armigera, Helicoverpa zea, and Heliothis virescens. J Invertebr Pathol. 2011;107:112-26 pubmed publisher
    ..found in insects of the heliothine pest complex, a PCR-based method was used to classify 90 samples of nucleopolyhedrovirus (NPV; Baculoviridae: Alphabaculovirus) obtained worldwide from larvae of Heliothis virescens, Helicoverpa ..
  76. Su J, Lung O, Blissard G. The Autographa californica multiple nucleopolyhedrovirus lef-5 gene is required for productive infection. Virology. 2011;416:54-64 pubmed publisher
    ..An egfp-tagged lef-5 gene from SeMNPV was used to generate a stable Sf9 cell line that supported replication of the vAc(lef5ko) virus. The LEF-5 protein was also found to co-localize with IE-1 in infected cell nuclei...
  77. Simón O, Palma L, Williams T, Lopez Ferber M, Caballero P. Analysis of a naturally-occurring deletion mutant of Spodoptera frugiperda multiple nucleopolyhedrovirus reveals sf58 as a new per os infectivity factor of lepidopteran-infecting baculoviruses. J Invertebr Pathol. 2012;109:117-26 pubmed publisher
    The Nicaraguan population of Spodoptera frugiperda multiple nucleopolyhedrovirus, SfMNPV-NIC, is structured as a mixture of nine genotypes (A-I)...
  78. Li Z, Blissard G. The Autographa californica multicapsid nucleopolyhedrovirus GP64 protein: analysis of transmembrane domain length and sequence requirements. J Virol. 2009;83:4447-61 pubmed publisher
    GP64, the major envelope glycoprotein of the Autographa californica multicapsid nucleopolyhedrovirus budded virion, is important for host cell receptor binding and mediates low-pH-triggered membrane fusion during entry by endocytosis...
  79. Sun J, Zhang E, Yao L, Zhang H, Jin P. A high efficient method of constructing recombinant Bombyx mori (silkworm) multiple nucleopolyhedrovirus based on zero-background Tn7-mediated transposition in Escherichia coli. Biotechnol Prog. 2009;25:524-9 pubmed publisher
    A high efficient way for generation of recombinant Bombyx mori (silkworm) multiple nucleopolyhedrovirus by Tn7-mediated transposition in Escherichia coli was performed...
  80. Lin L, Wang J, Deng R, Ke J, Wu H, Wang X. ac109 is required for the nucleocapsid assembly of Autographa californica multiple nucleopolyhedrovirus. Virus Res. 2009;144:130-5 pubmed publisher
    ORF109 (Ac109) of Autographa californica multiple nucleopolyhedrovirus (AcMNPV) is a highly conserved gene in all sequenced baculovirus genomes, but its function is not known...
  81. Nai Y, Wang T, Chen Y, Lo C, Wang C. A new nucleopolyhedrovirus strain (LdMNPV-like virus) with a defective fp25 gene from Lymantria xylina (Lepidoptera: Lymantriidae) in Taiwan. J Invertebr Pathol. 2009;102:110-9 pubmed publisher
    A new multiple nucleopolyhedrovirus strain was isolated from casuarina moth, Lymantria xylina Swinhoe, (Lepidoptera: Lymantriidae) in Taiwan...
  82. Ogembo J, Caoili B, Shikata M, Chaeychomsri S, Kobayashi M, Ikeda M. Comparative genomic sequence analysis of novel Helicoverpa armigera nucleopolyhedrovirus (NPV) isolated from Kenya and three other previously sequenced Helicoverpa spp. NPVs. Virus Genes. 2009;39:261-72 pubmed publisher
    A newly cloned Helicoverpa armigera nucleopolyhedrovirus (HearNPV) from Kenya, HearNPV-NNg1, has a higher insecticidal activity than HearNPV-G4, which also exhibits lower insecticidal activity than HearNPV-C1...
  83. Hoover K, Humphries M, Gendron A, Slavicek J. Impact of viral enhancin genes on potency of Lymantria dispar multiple nucleopolyhedrovirus in L. dispar following disruption of the peritrophic matrix. J Invertebr Pathol. 2010;104:150-2 pubmed publisher
    ..We compared the potency of wild-type Lymantria dispar multiple nucleopolyhedrovirus (LdMNPV) with that of single and double enhancin deletion viruses in L...
  84. Pedrini M, Reid S, Nielsen L, Chan L. Kinetic characterization of the group II Helicoverpa armigera nucleopolyhedrovirus propagated in suspension cell cultures: implications for development of a biopesticides production process. Biotechnol Prog. 2011;27:614-24 pubmed publisher
    ..have so far only been reported for the commercially established recombinant Autographa californica nucleopolyhedrovirus (AcMNPV), a Group I NPV...
  85. Shen H, Chen K. BM61 of Bombyx mori nucleopolyhedrovirus: its involvement in the egress of nucleocapsids from the nucleus. FEBS Lett. 2012;586:990-5 pubmed publisher
    All lepidopteran baculovirus genomes sequenced encode a homolog of the Bombyx mori nucleopolyhedrovirus orf61 gene (Bm61)...
  86. de Rezende S, Castro M, Souza M. Accumulation of few-polyhedra mutants upon serial passage of Anticarsia gemmatalis multiple nucleopolyhedrovirus in cell culture. J Invertebr Pathol. 2009;100:153-9 pubmed publisher
    Anticarsia gemmatalis nucleopolyhedrovirus (AgMNPV) has been widely used to control the velvetbean caterpillar, Anticarsia gemmatalis, in Brazil...
  87. Ogata M, Nakajima M, Kato T, Obara T, Yagi H, Kato K, et al. Synthesis of sialoglycopolypeptide for potentially blocking influenza virus infection using a rat alpha2,6-sialyltransferase expressed in BmNPV bacmid-injected silkworm larvae. BMC Biotechnol. 2009;9:54 pubmed publisher
    ..silkworm larval hemolymph using recombinant both cysteine protease- and chitinase-deficient Bombyx mori nucleopolyhedrovirus (BmNPV-CP--Chi-) bacmid...
  88. Xu F, Vlak J, Eker A, van Oers M. DNA photolyases of Chrysodeixis chalcites nucleopolyhedrovirus are targeted to the nucleus and interact with chromosomes and mitotic spindle structures. J Gen Virol. 2010;91:907-14 pubmed publisher
    ..phr genes encoding class II CPD photolyases PHR1 and PHR2 have been identified in Chrysodeixis chalcites nucleopolyhedrovirus (ChchNPV)...
  89. Wu C, Huang Y, Wang J, Wu Y, Lo H, Wang J, et al. Autographa californica multiple nucleopolyhedrovirus LEF-2 is a capsid protein required for amplification but not initiation of viral DNA replication. J Virol. 2010;84:5015-24 pubmed publisher
    The late expression factor 2 gene (lef-2) of baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been identified as one of the factors essential for origin-dependent DNA replication in transient expression assays ..
  90. Wang R, Deng F, Hou D, Zhao Y, Guo L, Wang H, et al. Proteomics of the Autographa californica nucleopolyhedrovirus budded virions. J Virol. 2010;84:7233-42 pubmed publisher
    ..In this study, the protein composition of the BV of Autographa californica nucleopolyhedrovirus (AcMNPV), the type species of baculoviruses, was analyzed by various mass spectrometry (MS) techniques, ..
  91. Li K, Wang Y, Bai H, Wang Q, Song J, Zhou Y, et al. The putative pocket protein binding site of Autographa californica nucleopolyhedrovirus BV/ODV-C42 is required for virus-induced nuclear actin polymerization. J Virol. 2010;84:7857-68 pubmed publisher
    ..Previously, we had demonstrated that Autographa californica multiple nucleopolyhedrovirus (AcMNPV) BV/ODV-C42 (C42) is involved in nuclear actin polymerization by recruiting P78/83, an AcMNPV orf9-..
  92. Sakamoto S, Pongkitwitoon B, Nakamura S, Maenaka K, Tanaka H, Morimoto S. Efficient silkworm expression of single-chain variable fragment antibody against ginsenoside Re using Bombyx mori nucleopolyhedrovirus bacmid DNA system and its application in enzyme-linked immunosorbent assay for quality control of total ginsenoside. J Biochem. 2010;148:335-40 pubmed publisher
    ..against ginsenoside Re (G-Re) have been successfully expressed in the silkworm larvae using Bombyx mori nucleopolyhedrovirus (BmNPV) bacmid DNA system...