pseudomonas phages

Summary

Summary: Viruses whose host is Pseudomonas. A frequently encountered Pseudomonas phage is BACTERIOPHAGE PHI 6.

Top Publications

  1. Mesyanzhinov V, Robben J, Grymonprez B, Kostyuchenko V, Bourkaltseva M, Sykilinda N, et al. The genome of bacteriophage phiKZ of Pseudomonas aeruginosa. J Mol Biol. 2002;317:1-19 pubmed
    ..However, limited homology on the DNA and protein levels indicates that bacteriophage phiKZ represents an evolutionary distinctive branch of the Myoviridae family...
  2. Hertveldt K, Lavigne R, Pleteneva E, Sernova N, Kurochkina L, Korchevskii R, et al. Genome comparison of Pseudomonas aeruginosa large phages. J Mol Biol. 2005;354:536-45 pubmed
    ..Besides a putative transposase, EL harbours predicted mobile endonucleases related to H-N-H and LAGLIDADG homing endonucleases associated with group I intron and intein intervening sequences...
  3. Kwan T, Liu J, DuBow M, Gros P, Pelletier J. Comparative genomic analysis of 18 Pseudomonas aeruginosa bacteriophages. J Bacteriol. 2006;188:1184-7 pubmed
    ..Comparative sequence analysis and ORF map organization revealed that most of the phages analyzed displayed little relationship to each other...
  4. Ceyssens P, Lavigne R, Mattheus W, Chibeu A, Hertveldt K, Mast J, et al. Genomic analysis of Pseudomonas aeruginosa phages LKD16 and LKA1: establishment of the phiKMV subgroup within the T7 supergroup. J Bacteriol. 2006;188:6924-31 pubmed
    ..Therefore, we propose that phiKMV represents an independent and widespread group of lytic P. aeruginosa phages within the T7 supergroup...
  5. Ceyssens P, Noben J, Ackermann H, Verhaegen J, De Vos D, Pirnay J, et al. Survey of Pseudomonas aeruginosa and its phages: de novo peptide sequencing as a novel tool to assess the diversity of worldwide collected viruses. Environ Microbiol. 2009;11:1303-13 pubmed publisher
    ..aeruginosa and the global spread of P. aeruginosa phage species, and points at the resistance of two clinically predominant, widespread P. aeruginosa strains against phage attack...
  6. Sillankorva S, Neubauer P, Azeredo J. Pseudomonas fluorescens biofilms subjected to phage phiIBB-PF7A. BMC Biotechnol. 2008;8:79 pubmed publisher
    ..Here we describe the application of phage phiIBB-PF7, a newly isolated phage, to control P. fluorescens biofilms. The biofilms were formed under static or dynamic conditions and with or without renewal of medium...
  7. Sillankorva S, Oliveira R, Vieira M, Azeredo J. Real-time quantification of Pseudomonas fluorescens cell removal from glass surfaces due to bacteriophage varphiS1 application. J Appl Microbiol. 2008;105:196-202 pubmed publisher
    ..To study the efficacy of the lytic phage varphiS1 in eliminating Pseudomonas fluorescens in the early stage of biofilm formation, using an in situ and real time methodology for cell quantification...
  8. Burkal tseva M, Krylov V, Pleteneva E, Shaburova O, Krylov S, Volkart G, et al. [Phenogenetic characterization of a group of giant Phi KZ-like bacteriophages of Pseudomonas aeruginosa]. Genetika. 2002;38:1470-9 pubmed
    ..Since the phage phi KZ genome codes for potentially toxic proteins, caution must be exercised in the employment of large bacteriophages in phage therapy...
  9. Morgan A, Brockhurst M, Lopez Pascua L, Pal C, Buckling A. Differential impact of simultaneous migration on coevolving hosts and parasites. BMC Evol Biol. 2007;7:1 pubmed
    ..However, previous studies suggest phages should benefit more from migration than bacteria; because in the absence of migration, phages are more genetically limited and have a lower evolutionary potential compared to the bacteria...

More Information

Publications71

  1. Cornelissen A, Hardies S, Shaburova O, Krylov V, Mattheus W, Kropinski A, et al. Complete genome sequence of the giant virus OBP and comparative genome analysis of the diverse ?KZ-related phages. J Virol. 2012;86:1844-52 pubmed publisher
  2. Debarbieux L, Leduc D, Maura D, Morello E, Criscuolo A, Grossi O, et al. Bacteriophages can treat and prevent Pseudomonas aeruginosa lung infections. J Infect Dis. 2010;201:1096-104 pubmed publisher
  3. Lecoutere E, Ceyssens P, Miroshnikov K, Mesyanzhinov V, Krylov V, Noben J, et al. Identification and comparative analysis of the structural proteomes of phiKZ and EL, two giant Pseudomonas aeruginosa bacteriophages. Proteomics. 2009;9:3215-9 pubmed publisher
    ..The phiKZ structural proteome strongly correlates to that of Pseudomonas chlororaphis bacteriophage 201phi2-1. Phage EL is more distantly related, shown by its 26 non-conserved structural proteins and the presence of genomic inversions...
  4. Braid M, Silhavy J, Kitts C, Cano R, Howe M. Complete genomic sequence of bacteriophage B3, a Mu-like phage of Pseudomonas aeruginosa. J Bacteriol. 2004;186:6560-74 pubmed
    ..These differences illustrate and support the widely held view that tailed phages are genetic mosaics arising by the exchange of functional modules within a diverse genetic pool...
  5. Krylov V, Dela Cruz D, Hertveldt K, Ackermann H. "phiKZ-like viruses", a proposed new genus of myovirus bacteriophages. Arch Virol. 2007;152:1955-9 pubmed
    ..The genome of the type virus, phiKZ, has 306 ORFs and over 280 kbp and is the second-largest phage genome known. The phiKZ genus has very few relationships to other phages and includes three species and one possible species...
  6. McVay C, Velasquez M, Fralick J. Phage therapy of Pseudomonas aeruginosa infection in a mouse burn wound model. Antimicrob Agents Chemother. 2007;51:1934-8 pubmed
    ..m. or s.c. route, which may explain the differences in the efficacies of these three different routes of administration...
  7. Nakayama K, Kanaya S, Ohnishi M, Terawaki Y, Hayashi T. The complete nucleotide sequence of phi CTX, a cytotoxin-converting phage of Pseudomonas aeruginosa: implications for phage evolution and horizontal gene transfer via bacteriophages. Mol Microbiol. 1999;31:399-419 pubmed
    ..They appear to be deeply concerned in the acquisition of various genes that are horizontally transferred by bacteriophage infection...
  8. Tan Y, Zhang K, Rao X, Jin X, Huang J, Zhu J, et al. Whole genome sequencing of a novel temperate bacteriophage of P. aeruginosa: evidence of tRNA gene mediating integration of the phage genome into the host bacterial chromosome. Cell Microbiol. 2007;9:479-91 pubmed
    ..The results indicated that 3'-end of tRNA(Pro) gene of the PaP3 genome is involved in the integration reaction and 5'-end of tRNA(Lys) gene of host bacteria genome is hot spot of the integration...
  9. Ceyssens P, Hertveldt K, Ackermann H, Noben J, Demeke M, Volckaert G, et al. The intron-containing genome of the lytic Pseudomonas phage LUZ24 resembles the temperate phage PaP3. Virology. 2008;377:233-8 pubmed publisher
    ..The lytic characteristics of LUZ24 are evaluated against its genomic content, which displays an overall 71% sequence similarity to the temperate phage PaP3...
  10. Ceyssens P, BRABBAN A, Rogge L, Lewis M, Pickard D, Goulding D, et al. Molecular and physiological analysis of three Pseudomonas aeruginosa phages belonging to the "N4-like viruses". Virology. 2010;405:26-30 pubmed publisher
    ..detailed analysis of the genome architecture, structural proteome and infection-related properties of three Pseudomonas phages, designated LUZ7, LIT1 and PEV2. These podoviruses encapsulate 72.5 to 74...
  11. Garbe J, Bunk B, Rohde M, Schobert M. Sequencing and characterization of Pseudomonas aeruginosa phage JG004. BMC Microbiol. 2011;11:102 pubmed publisher
    ..g. Pseudomonas aeruginosa. For an effective use of bacteriophages as antimicrobial agents, it is important to understand phage biology but also genes of the bacterial host essential for phage infection...
  12. Lopez Pascua L, Gandon S, Buckling A. Abiotic heterogeneity drives parasite local adaptation in coevolving bacteria and phages. J Evol Biol. 2012;25:187-95 pubmed publisher
    ..These results demonstrate that the abiotic environment can play a strong and predictable role in driving patterns of local adaptation...
  13. Zhang Q, Buckling A. Antagonistic coevolution limits population persistence of a virus in a thermally deteriorating environment. Ecol Lett. 2011;14:282-8 pubmed publisher
    ..The results highlight the importance of interspecific evolutionary interactions for the evolutionary responses of populations to global climate change...
  14. Fokine A, Kostyuchenko V, Efimov A, Kurochkina L, Sykilinda N, Robben J, et al. A three-dimensional cryo-electron microscopy structure of the bacteriophage phiKZ head. J Mol Biol. 2005;352:117-24 pubmed
    ..The double-stranded genomic DNA is packaged into a highly condensed series of layers, separated by 24 A, that follow the contour of the inner wall of the capsid...
  15. Sillankorva S, Oliveira R, Vieira M, Sutherland I, Azeredo J. Pseudomonas fluorescens infection by bacteriophage PhiS1: the influence of temperature, host growth phase and media. FEMS Microbiol Lett. 2004;241:13-20 pubmed
    ..The host physiological state also affected these rates. Infection was dependent on the presence of cell wall proteins with molecular weights of 17.5+/-1 and 99+/-5 kDa...
  16. Ceyssens P, Lavigne R. Bacteriophages of Pseudomonas. Future Microbiol. 2010;5:1041-55 pubmed publisher
    ..Here, we summarize recent molecular research performed on Pseudomonas phages by reviewing findings on individual phage genera...
  17. Gomez P, Buckling A. Bacteria-phage antagonistic coevolution in soil. Science. 2011;332:106-9 pubmed publisher
    ..These results suggest that rapid coevolution between bacteria and phage is likely to play a key role in structuring natural microbial communities...
  18. Nzula S, Vandamme P, Govan J. Sensitivity of the Burkholderia cepacia complex and Pseudomonas aeruginosa to transducing bacteriophages. FEMS Immunol Med Microbiol. 2000;28:307-12 pubmed
    ..The lytic activity of NS1 and NS2 was inhibited by B. cepacia lipopolysaccharide suggesting that this moiety is a binding site for both phages. The molecular size of the NS1 and NS2 genomes was approximately 48 kb...
  19. Ceyssens P, Miroshnikov K, Mattheus W, Krylov V, Robben J, Noben J, et al. Comparative analysis of the widespread and conserved PB1-like viruses infecting Pseudomonas aeruginosa. Environ Microbiol. 2009;11:2874-83 pubmed publisher
    ..These PB1-like viruses constitute a new genus of environmentally very widespread phages within the Myoviridae...
  20. Cady K, O Toole G. Non-identity-mediated CRISPR-bacteriophage interaction mediated via the Csy and Cas3 proteins. J Bacteriol. 2011;193:3433-45 pubmed publisher
    ..This work demonstrates how the interaction between P. aeruginosa strain UCBPP-PA14 and bacteriophage DMS3 can be used to further our understanding of the diverse roles of CRISPR system function in bacteria...
  21. Scanlan P, Hall A, Lopez Pascua L, Buckling A. Genetic basis of infectivity evolution in a bacteriophage. Mol Ecol. 2011;20:981-9 pubmed publisher
    ..An understanding of the molecular genetics of phage infectivity has helped to explain the complex phenotypic coevolutionary dynamics in this system...
  22. Kropinski A. Sequence of the genome of the temperate, serotype-converting, Pseudomonas aeruginosa bacteriophage D3. J Bacteriol. 2000;182:6066-74 pubmed
    ..Among the ORFs was discovered the gene encoding the fucosamine O-acetylase, which is in part responsible for the serotype conversion events...
  23. Hanlon G, Denyer S, Olliff C, Ibrahim L. Reduction in exopolysaccharide viscosity as an aid to bacteriophage penetration through Pseudomonas aeruginosa biofilms. Appl Environ Microbiol. 2001;67:2746-53 pubmed
    ..The data suggest that bacteriophage migration through P. aeruginosa biofilms may be facilitated by a reduction in alginate viscosity brought about by enzymic degradation and that the source of the enzyme may be the bacterial host itself...
  24. Sepúlveda Robles O, Kameyama L, Guarneros G. High diversity and novel species of Pseudomonas aeruginosa bacteriophages. Appl Environ Microbiol. 2012;78:4510-5 pubmed publisher
    ..This finding increased the group diversity by ~30%. The great diversity of phage species could be related to the ubiquitous nature of P. aeruginosa...
  25. Ceyssens P, Mesyanzhinov V, Sykilinda N, Briers Y, Roucourt B, Lavigne R, et al. The genome and structural proteome of YuA, a new Pseudomonas aeruginosa phage resembling M6. J Bacteriol. 2008;190:1429-35 pubmed
    ..The genome organization of both phages differs substantially from those of the other known Pseudomonas-infecting Siphoviridae, delineating them as a distinct genus within this family...
  26. Chung I, Cho Y. Complete genome sequences of two Pseudomonas aeruginosa temperate phages, MP29 and MP42, which lack the phage-host CRISPR interaction. J Virol. 2012;86:8336 pubmed publisher
    ..Both MP29 and MP42 lysogens, however, were proficient in swarming, suggesting the absence of the phage-host CRISPR interaction...
  27. Adriaenssens E, Mattheus W, Cornelissen A, Shaburova O, Krylov V, Kropinski A, et al. Complete genome sequence of the giant Pseudomonas phage Lu11. J Virol. 2012;86:6369-70 pubmed publisher
    ..The closest relative is Ralstonia phage ?RSL1, encoding 40 similar proteins. As such, Lu11 can be considered phylogenetically unique within the Myoviridae and indicates the diversity of the giant phages within this family...
  28. Piekarowicz A, Kłyz A, Majchrzak M, Adamczyk Popławska M, Maugel T, Stein D. Characterization of the dsDNA prophage sequences in the genome of Neisseria gonorrhoeae and visualization of productive bacteriophage. BMC Microbiol. 2007;7:66 pubmed
    ..The distribution, conservation and function of many of these sequences, and their ability to produce bacteriophage particles are unknown...
  29. Alemayehu D, Casey P, McAuliffe O, Guinane C, Martin J, Shanahan F, et al. Bacteriophages ?MR299-2 and ?NH-4 can eliminate Pseudomonas aeruginosa in the murine lung and on cystic fibrosis lung airway cells. MBio. 2012;3:e00029-12 pubmed publisher
  30. Vogwill T, Fenton A, Brockhurst M. The impact of parasite dispersal on antagonistic host-parasite coevolution. J Evol Biol. 2008;21:1252-8 pubmed publisher
  31. Kirov S, Webb J, O may C, Reid D, Woo J, Rice S, et al. Biofilm differentiation and dispersal in mucoid Pseudomonas aeruginosa isolates from patients with cystic fibrosis. Microbiology. 2007;153:3264-74 pubmed
    ..aeruginosa in the CF airway...
  32. Park S, Nakai T. Bacteriophage control of Pseudomonas plecoglossicida infection in ayu Plecoglossus altivelis. Dis Aquat Organ. 2003;53:33-9 pubmed
    ..Neither phage-resistant organisms nor phage-neutralizing antibodies were detected in diseased fish or apparently healthy fish, respectively. These results indicate the potential for phage control of the disease...
  33. Knezevic P, Kostanjsek R, Obreht D, Petrovic O. Isolation of Pseudomonas aeruginosa specific phages with broad activity spectra. Curr Microbiol. 2009;59:173-80 pubmed publisher
    ..Digested DNA of the phages delta and I showed similar patterns, indicating the prevalence and success of this phage type in the environment...
  34. Lopez Pascua L, Buckling A. Increasing productivity accelerates host-parasite coevolution. J Evol Biol. 2008;21:853-60 pubmed publisher
    ..The data further suggest that variation in productivity can generate variation in selection for resistance across landscapes, a result that is crucial to the geographic mosaic theory of coevolution...
  35. Watanabe R, Matsumoto T, Sano G, Ishii Y, Tateda K, Sumiyama Y, et al. Efficacy of bacteriophage therapy against gut-derived sepsis caused by Pseudomonas aeruginosa in mice. Antimicrob Agents Chemother. 2007;51:446-52 pubmed
    ..In conclusion, our findings suggest that oral administration of phage may be effective against gut-derived sepsis caused by P. aeruginosa...
  36. Chibeu A, Ceyssens P, Hertveldt K, Volckaert G, Cornelis P, Matthijs S, et al. The adsorption of Pseudomonas aeruginosa bacteriophage phiKMV is dependent on expression regulation of type IV pili genes. FEMS Microbiol Lett. 2009;296:210-8 pubmed publisher
  37. Vogwill T, Fenton A, Buckling A, Hochberg M, Brockhurst M. Source populations act as coevolutionary pacemakers in experimental selection mosaics containing hotspots and coldspots. Am Nat. 2009;173:E171-6 pubmed publisher
    ..These results confirm theoretical predictions and suggest that source populations can act as coevolutionary "pacemakers" for recipient populations, overriding local conditions...
  38. Nakai T, Park S. Bacteriophage therapy of infectious diseases in aquaculture. Res Microbiol. 2002;153:13-8 pubmed
    ..Here we describe the protective effects of phages against experimentally induced bacterial infections of cultured fish and discuss the potential for phage therapy in aquaculture...
  39. Hoogstraten D, Qiao X, Sun Y, Hu A, Onodera S, Mindich L. Characterization of phi8, a bacteriophage containing three double-stranded RNA genomic segments and distantly related to Phi6. Virology. 2000;272:218-24 pubmed publisher
    ..The host range of Phi8 includes rough strains of Salmonella typhimurium and of pseudomonads..
  40. Ashelford K, Day M, Fry J. Elevated abundance of bacteriophage infecting bacteria in soil. Appl Environ Microbiol. 2003;69:285-9 pubmed
    ..Thus, soil phage, like their aquatic counterparts, are likely to be important in controlling bacterial populations and mediating gene transfer in soil...
  41. Sillankorva S, Neubauer P, Azeredo J. Isolation and characterization of a T7-like lytic phage for Pseudomonas fluorescens. BMC Biotechnol. 2008;8:80 pubmed publisher
    ..Here we describe the isolation and characterization of a lytic phage capable to infect a variety of P. fluorescens strains isolated from Portuguese and United States dairy industries...
  42. Uchiyama J, Rashel M, Takemura I, Kato S, Ujihara T, Muraoka A, et al. Genetic characterization of Pseudomonas aeruginosa bacteriophage KPP10. Arch Virol. 2012;157:733-8 pubmed publisher
    ..aeruginosa. Phage KPP10 is considered to be suitable for therapeutic purposes because it is a lytic phage without ORF-encoded pathogenicity or a lysogenization factors...
  43. Morgan A, Buckling A. Relative number of generations of hosts and parasites does not influence parasite local adaptation in coevolving populations of bacteria and phages. J Evol Biol. 2006;19:1956-63 pubmed
    ..Taken together, these data suggest that the relative generation times of hosts and parasites may not be an important determinant of local adaptation in this system...
  44. Klimuk E, Akulenko N, Makarova K, Ceyssens P, Volchenkov I, Lavigne R, et al. Host RNA polymerase inhibitors encoded by ?KMV-like phages of Pseudomonas. Virology. 2013;436:67-74 pubmed publisher
    ..This finding indicates that Pseudomonas phages may use external or internal cues to initiate inhibition of host RNAP transcription and that gp2-like ..
  45. Pourcel C, Midoux C, Vergnaud G, Latino L. A carrier state is established in Pseudomonas aeruginosa by phage LeviOr01, a newly isolated ssRNA levivirus. J Gen Virol. 2017;98:2181-2189 pubmed publisher
    ..The present results highlight the importance of the carrier state, an association that benefits both phages and bacteria and plays a role in bacterial evolution. ..
  46. Alber J, Langewische F, Adebayo A, Lutz F. Organization and activation of the late promoters of phiCTX, a cytotoxin-converting phage from Pseudomonas aeruginosa. Mol Genet Genomics. 2002;267:38-44 pubmed
    ..Whereas the late promoters were active in P. aeruginosa, only weak beta-galactosidase activity was obtained in E. coli. ..
  47. Val M, Bouvier M, Campos J, Sherratt D, Cornet F, Mazel D, et al. The single-stranded genome of phage CTX is the form used for integration into the genome of Vibrio cholerae. Mol Cell. 2005;19:559-66 pubmed
    ..This integration strategy explains why the rules that normally apply to tyrosine recombinase reactions seemed not to apply to CTXvarphi integration and, in particular, why integration is irreversible. ..
  48. Kim M, Cha K, Myung H. Complete genome of Pseudomonas aeruginosa phage PA26. J Virol. 2012;86:10244 pubmed publisher
    ..It was found to belong to the myoviridae by an electron microscopic observation. It had a linear double-stranded DNA genome of 72,321 bp. Genomic analysis showed that it resembled another Pseudomonas phage, LIT1. ..
  49. Hayashi T, Matsumoto H, Ohnishi M, Terawaki Y. Molecular analysis of a cytotoxin-converting phage, phi CTX, of Pseudomonas aeruginosa: structure of the attP-cos-ctx region and integration into the serine tRNA gene. Mol Microbiol. 1993;7:657-67 pubmed
    ..In addition, phi CTX was found to integrate into the serine tRNA gene which was mapped to the 43-45 min region on the P. aeruginosa chromosome. ..
  50. Kim S, Rahman M, Seol S, Yoon S, Kim J. Pseudomonas aeruginosa bacteriophage PA1Ø requires type IV pili for infection and shows broad bactericidal and biofilm removal activities. Appl Environ Microbiol. 2012;78:6380-5 pubmed publisher
    ..PA1Ø may be developed as a therapeutic agent for biofilm-related mixed infections with P. aeruginosa and Staphylococcus aureus. ..
  51. Lim F, Peabody D. RNA recognition site of PP7 coat protein. Nucleic Acids Res. 2002;30:4138-44 pubmed
    ..However, another structural class possessing only some of these features is capable of binding almost as tightly. ..
  52. Krylov V. Bacteriophages of Pseudomonas aeruginosa: long-term prospects for use in phage therapy. Adv Virus Res. 2014;88:227-78 pubmed publisher
    ..aeruginosa phages and organizational arrangements (as banks of phages) to ensure long-term use of phages in the treatment of P. aeruginosa infections. ..
  53. Hawkins C, Harper D, Burch D, Anggård E, Soothill J. Topical treatment of Pseudomonas aeruginosa otitis of dogs with a bacteriophage mixture: a before/after clinical trial. Vet Microbiol. 2010;146:309-13 pubmed publisher
    ..aeruginosa in the ear without apparent toxicity and that it has potential to be a convenient and effective treatment for P. aeruginosa otitis in dogs...
  54. Rajal V, McSwain B, Thompson D, Leutenegger C, Kildare B, Wuertz S. Validation of hollow fiber ultrafiltration and real-time PCR using bacteriophage PP7 as surrogate for the quantification of viruses from water samples. Water Res. 2007;41:1411-22 pubmed
  55. Tsuboi M, Overman S, Nakamura K, Rodríguez Casado A, Thomas G. Orientation and interactions of an essential tryptophan (Trp-38) in the capsid subunit of Pf3 filamentous virus. Biophys J. 2003;84:1969-76 pubmed
    ..Such a C-terminal Trp-38/Arg-37 interaction may be important for the stabilization of a subunit conformation that is required for binding to the single-stranded DNA genome during virion assembly...
  56. Shaburova O, Pleteneva E, Hertveldt K, Krylov V. [Comparison of DNA sizes in a group of giant Pseudomonas aeruginosa phages by the PFGE method]. Genetika. 2008;44:713-6 pubmed
    ..Putative "redundant" genes in phiKZ phage genome are supposed to control functions promoting vigorous growth of the phage belonging to this species, compared to phages of EL species...
  57. Matsko N, Klinov D, Manykin A, Demin V, Klimenko S. Atomic force microscopy analysis of bacteriophages phiKZ and T4. J Electron Microsc (Tokyo). 2001;50:417-22 pubmed
    ..We have established a procedure to partially disintegrate the viral particles after which the internal protein body, which is a helical structure with a cylinder-like form, was easily observable inside the bacteriophage phiKZ head...
  58. Nishihara T, Fujisaki S, Nishimura Y, Minami Y, Yubisui T. Analysis of six new genes encoding lysis proteins and coat proteins in Escherichia coli group A RNA phages. Microbiol Immunol. 2006;50:61-6 pubmed
    ..The phylogenetic analysis shows that the sub-groups A-I and A-II of E. coli RNA phages were clearly dispersed into two clusters...
  59. Sillankorva S, Pires D, Oliveira H, Neubauer P, Azeredo J. The influence of P. fluorescens cell morphology on the lytic performance and production of phage ?IBB-PF7A. Curr Microbiol. 2011;63:347-53 pubmed publisher
    ..The results of this study suggest that the change of rod cells to an elongated morphology does not prevent cells from being attacked by phages and also does not impair the phage infection...
  60. Hesse E, Buckling A. Host population bottlenecks drive parasite extinction during antagonistic coevolution. Evolution. 2016;70:235-40 pubmed publisher
    ..Our findings emphasize the importance of feedbacks between ecological and coevolutionary dynamics, and how this feedback can qualitatively alter coevolutionary dynamics. ..
  61. Kurochkina L, Aksyuk A, Sachkova M, Sykilinda N, Mesyanzhinov V. Characterization of tail sheath protein of giant bacteriophage phiKZ Pseudomonas aeruginosa. Virology. 2009;395:312-7 pubmed publisher
    ..Although there is no sequence homology of phiKZ proteins to proteins of other bacteriophages, some characteristic biochemical properties of gp29 revealed similarities to the tail sheath protein of bacteriophage T4...
  62. Thomas J, Weintraub S, Wu W, Winkler D, Cheng N, Steven A, et al. Extensive proteolysis of head and inner body proteins by a morphogenetic protease in the giant Pseudomonas aeruginosa phage ?KZ. Mol Microbiol. 2012;84:324-39 pubmed publisher
    ..Together the six abundant proteins sum to the estimated mass of the inner body (15-20 MDa). The identification of these proteins is important for future studies on the composition and function of the inner body...