viral hemorrhagic fevers

Summary

Summary: A group of viral diseases of diverse etiology but having many similar clinical characteristics; increased capillary permeability, leukopenia, and thrombocytopenia are common to all. Hemorrhagic fevers are characterized by sudden onset, fever, headache, generalized myalgia, backache, conjunctivitis, and severe prostration, followed by various hemorrhagic symptoms. Hemorrhagic fever with kidney involvement is HEMORRHAGIC FEVER WITH RENAL SYNDROME.

Webpages

  1. safety and health topics: viral hemorrhagic fevers (vhfs
    www.osha.gov/SLTC/vhf/index.html
  2. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#tular ...
  3. biological agents: anthrax, small pox, plague, virus - texas
    texashelp.tamu.edu/006-violence-terrorism/biological-agents. ...
  4. acp: bioterrorism and disaster preparedness
    www.acponline.org/clinical_information/resources/bioterroris ...
  5. acp: bioterrorism and disaster preparedness
    www.acponline.org/clinical_information/resources/bioterroris ...
  6. acp - pda portal
    www.acponline.org/running_practice/technology/mobile_computi ...
  7. bioterrorism sources
    www.lib.uchicago.edu/e/su/sci/biot.html
  8. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#anthr ...
  9. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#botul ...
  10. division of specialized information services creates biological warfare site
    www.nlm.nih.gov/news/sisbiolwar02.html

Research Grants

  1. 1 Z01 AI000938-03 RV Paramyxoviruses as Vaccine Vectors
    Peter L Collins; Fiscal Year: 2006
  2. Cytokine patterns in guinea pig arenavirus disease
    Judith F Aronson; Fiscal Year: 2004
  3. Therapeutics for Pox, Filo and Other Viral Pathogens
    Stewart W Schneller; Fiscal Year: 2007
  4. Recombinant Yellow Fever 17D-Lassa Vaccine
    Igor S Lukashevich; Fiscal Year: 2008
  5. Recombinant Yellow Fever 17D-Lassa Vaccine
    Igor S Lukashevich; Fiscal Year: 2007
  6. Aminoglycoside Antivirals to Combat Arenaviruses
    Juan C de la Torre; Fiscal Year: 2004
  7. Pathobiology and Small-Molecule Inhibition of Arenavirus Infection
    ANDREW MICHAEL LEE; Fiscal Year: 2008
  8. Pathobiology and Small-Molecule Inhibition of Arenavirus Infection
    ANDREW MICHAEL LEE; Fiscal Year: 2007
  9. Neutralizing Compounds for Viral Hemorrhagic Fever
    Richard S Larson; Fiscal Year: 2005
  10. B.abortus-based vaccine against viral hemorrhagic fevers
    Ramesh Vemulapalli; Fiscal Year: 2004

Publications

  1. Confronting bioterrorism: physicians on the front line
    Prathibha Varkey
    Division of Preventive Medicine and Occupational Medicine and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 77:661-72
  2. Syndromic surveillance and bioterrorism-related epidemics
    James W Buehler
    Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Emerg Infect Dis 9:1197-204
  3. Histopathology and immunohistochemistry in the diagnosis of bioterrorism agents
    Jeannette Guarner
    Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Mailstop G32, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    J Histochem Cytochem 54:3-11
  4. Bioterrorism and catastrophe response: a quick-reference guide to resources
    Susan Z Han
    Harvard School of Dental Medicine, Boston, USA
    J Am Dent Assoc 134:745-52
  5. Molecular diagnostic techniques for use in response to bioterrorism
    Marcia A Firmani
    Department of Clinical Laboratory Sciences, Louisiana State University Health Sciences Center, 1900 Gravier Street, New Orleans, LA 70112 2223, USA
    Expert Rev Mol Diagn 3:605-16
  6. Recognition and management of bioterrorism infections
    Mark L Higdon
    Family Practice Residency Program, Martin Army Community Hospital, Fort Benning, Georgia, USA
    Am Fam Physician 67:1927-34
  7. Threats in bioterrorism. I: CDC category A agents
    Robert G Darling
    Operational Medicine Division, US Army Medical Research Institute of Infectious Diseases USAMRIID, 1425 Porter Street, ATTN MCMR UIM O, Fort Detrick, MD 21702 5011, USA
    Emerg Med Clin North Am 20:273-309
  8. Bioterrorism: a clinical reality
    Robert J Leggiadro
    Lincoln Medical and Mental Health Center, Bronx, NY, USA
    Pediatr Ann 36:352-8
  9. [Emerging or re-emerging infections that can be used for bioterrorism]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitié Salpêtrière, 47 83, boulevard de l Hôpital, 75013 Paris, France
    Presse Med 34:149-55
  10. Biological and chemical agents: a brief synopsis
    Mark Rosenbloom
    Northwestern University School of Medicine, Chicago, IL, USA
    Am J Ther 9:5-14

Scientific Experts

Detail Information

Webpages64 found, 30 most recent shown here

  1. safety and health topics: viral hemorrhagic fevers (vhfs
    www.osha.gov/SLTC/vhf/index.html
  2. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#tular ...
  3. biological agents: anthrax, small pox, plague, virus - texas
    texashelp.tamu.edu/006-violence-terrorism/biological-agents. ...
  4. acp: bioterrorism and disaster preparedness
    www.acponline.org/clinical_information/resources/bioterroris ...
  5. acp: bioterrorism and disaster preparedness
    www.acponline.org/clinical_information/resources/bioterroris ...
  6. acp - pda portal
    www.acponline.org/running_practice/technology/mobile_computi ...
  7. bioterrorism sources
    www.lib.uchicago.edu/e/su/sci/biot.html
  8. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#anthr ...
  9. nyusm chip
    chip.med.nyu.edu/datafiles/mostcited/mostcitedbio.html#botul ...
  10. division of specialized information services creates biological warfare site
    www.nlm.nih.gov/news/sisbiolwar02.html
  11. bush approves quarantine authority for mystery illness
    www.rmi.gsu.edu/rmi/faculty/klein/RMI_3500/Readings/Other/SA ...
  12. junin virus
    pathport.vbi.vt.edu/pathinfo/pathogens/Junin_virus.html
  13. biocontainment unit - health services - the nebraska medical center
    www.nhsnet.org/Services/BiocontainmentUnit/Default.aspx
  14. factsheet: crimean-congo hemorrhagic fever | cdc special pathogens branch
    www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/omsk.htm
  15. lassa fever | cdc special pathogens branch
    www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lassaf.htm
  16. lymphocytic choriomeningitis (lcmv) | cdc special pathogens branch
    www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/lcmv/qa.htm
  17. factsheet: crimean-congo hemorrhagic fever | cdc special pathogens branch
    www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/kyasanur.htm
  18. high risk diseases for travelers, robert wood johnson university hospital, new brunswick, nj, 08903
    www.rwjuh.edu/health_information/adult_travel_highhub.html
  19. non-dengue viral hemorrhagic fevers
    www.tropical.umn.edu/TTM/Cases/talks/Hemorrhagic Fever_files ...
  20. vm9086, advanced emerging infectious diseases, homepage
    courses.iddl.vt.edu/AEID_II/
  21. marburg hemorrhagic fever: cdc assists in public health response to marburg hemorrhagic fever outbreak in angola | cdc special pathogens branch
    www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/marburg/cdcrole ...
  22. non-dengue viral hemorrhagic fevers
    www.tropical.umn.edu/TTM/Cases/talks/Hemorrhagic Fever_files ...
  23. high risk diseases for travelers - travel medicine - the nebraska medical center
    www.nhsnet.org/ManageHealth/libraries/Default.aspx?P=1440
  24. our physicians - health information
    www.memorialhealth.com/healthinfo/content.aspx?pageid=P01464
  25. topic index - travel medicine - travel medicine - the nebraska medical center
    www.nhsnet.org/ManageHealth/libraries/Default.aspx?P=1456
  26. our physicians - health information
    www.memorialhealth.com/healthinfo/content.aspx?pageid=P01440
  27. news and press room, robert wood johnson university hospital, new brunswick, nj
    www.rwjuh.edu/health_information/conditions.aspx?a1=v

Research Grants21

  1. 1 Z01 AI000938-03 RV Paramyxoviruses as Vaccine Vectors
    Peter L Collins; Fiscal Year: 2006
    ..These data suggest the feasibility of intranasal immunization against severe viral hemorrhagic fevers. The immunogenicity and protective efficacy of the vectored vaccine did not appear to be enhanced by co-..
  2. Cytokine patterns in guinea pig arenavirus disease
    Judith F Aronson; Fiscal Year: 2004
    ..cytokines are important effectors in the terminal pathophysiology of septic shock and other viral hemorrhagic fevers, and some have direct anti-viral effects in cultured cells...
  3. Therapeutics for Pox, Filo and Other Viral Pathogens
    Stewart W Schneller; Fiscal Year: 2007
    ..Among that group of pathogens are smallpox and the viral hemorrhagic fevers (including the filoviruses Ebola and Marburg)...
  4. Recombinant Yellow Fever 17D-Lassa Vaccine
    Igor S Lukashevich; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Yellow Fever (YF) and Lassa Fever (LF) are two viral hemorrhagic fevers (VHFs) endemic for West and Central Africa...
  5. Recombinant Yellow Fever 17D-Lassa Vaccine
    Igor S Lukashevich; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Yellow Fever (YF) and Lassa Fever (LF) are two viral hemorrhagic fevers (VHFs) endemic for West and Central Africa...
  6. Aminoglycoside Antivirals to Combat Arenaviruses
    Juan C de la Torre; Fiscal Year: 2004
    ..that cause important and severe human diseases like Lassa fever virus (LFV) and the South American viral hemorrhagic fevers (SAHF). In addition, weaponized forms of these viruses pose a real threat as agents of bioterrorism...
  7. Pathobiology and Small-Molecule Inhibition of Arenavirus Infection
    ANDREW MICHAEL LEE; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Viral hemorrhagic fevers represent a serious public health problem, with recurring outbreaks of hemorrhagic fever occurring in all parts of the world...
  8. Pathobiology and Small-Molecule Inhibition of Arenavirus Infection
    ANDREW MICHAEL LEE; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Viral hemorrhagic fevers represent a serious public health problem, with recurring outbreaks of hemorrhagic fever occurring in all parts of the world...
  9. Neutralizing Compounds for Viral Hemorrhagic Fever
    Richard S Larson; Fiscal Year: 2005
    ..The CDC has ranked viral hemorrhagic fevers (VHP) among the highest of the potential bioterror threats, in part because of their high case-fatality ..
  10. B.abortus-based vaccine against viral hemorrhagic fevers
    Ramesh Vemulapalli; Fiscal Year: 2004
    DESCRIPTION (provided by applicant): Viral hemorrhagic fevers (VHF) are severe and life-threatening diseases caused by several viruses...
  11. TF Signaling in Systemic Inflammation
    Wolfram Ruf; Fiscal Year: 2008
    ..is a hallmark of diverse systemic inflammatory response syndromes associated with bacterial sepsis and viral hemorrhagic fevers. In the previous funding period of this grant, we have used a mouse model of severe endotoxemia to define ..
  12. Identification of Ebola Virus Entry Inhibitors
    Arnab Basu; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Ebola virus (EBOV) causes periodic outbreaks of severe viral hemorrhagic fevers in Africa with high mortality rates in infected patients...
  13. A Cellular Receptor for New World Arenaviruses
    Hyeryun Choe; Fiscal Year: 2008
    DESCRIPTION (provided by applicant): Arenaviruses cause severe viral hemorrhagic fevers in humans...
  14. A Cellular Receptor for New World Arenaviruses
    Hyeryun Choe; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Arenaviruses cause severe viral hemorrhagic fevers in humans...
  15. Chimeric VLP Vaccines for Viral Hemorrhagic Fever
    Richard W Compans; Fiscal Year: 2003
    DESCRIPTION (provided by applicant): Viral hemorrhagic fevers (VHF's) involve severe disease symptoms and high mortality rates, and the potential for natural reemergence and spread of the viral agents...
  16. Host Genetics and Symptomatic Dengue Infection
    Ronald E Blanton; Fiscal Year: 2004
    ..The results of this study may help predict populations at risk, may influence vaccine design or may aid in understanding and managing other viral hemorrhagic fevers.
  17. Genetics of Innate Immunity in Human Leptospirosis in Brazil
    Joseph M Vinetz; Fiscal Year: 2007
    ..The fulminant hemorrhagic form of leptospirosis can closely mimic a number of viral hemorrhagic fevers caused by potential bioterrorism agents...
  18. Genetics of Innate Immunity in Human Leptospirosis in Brazil
    Joseph M Vinetz; Fiscal Year: 2008
    ..The fulminant hemorrhagic form of leptospirosis can closely mimic a number of viral hemorrhagic fevers caused by potential bioterrorism agents...
  19. Neutralizing Compounds for Viral Hemorrhagic Fever
    Richard S Larson; Fiscal Year: 2003
    ..The CDC has ranked viral hemorrhagic fevers (VHF) among the highest of the potential bioterror threats, in part because of their high case-fatality ..
  20. CTL pathogenesis after infection of vaccinated host
    John T Harty; Fiscal Year: 2008
    ..Finally, agents that cause viral hemorrhagic fevers, including some LCMV strains, are CDC class A biodefense agents...
  21. CTL pathogenesis after infection of vaccinated host
    John T Harty; Fiscal Year: 2007
    ..Finally, agents that cause viral hemorrhagic fevers, including some LCMV strains, are CDC class A biodefense agents...

Publications62

  1. Confronting bioterrorism: physicians on the front line
    Prathibha Varkey
    Division of Preventive Medicine and Occupational Medicine and Internal Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 77:661-72
    ..The diseases discussed include anthrax, smallpox, tularemia, plague, botulism, and viral hemorrhagic fevers. Despite the unpredictable nature of bioterrorism, disaster preparedness and knowledge of essential ..
  2. Syndromic surveillance and bioterrorism-related epidemics
    James W Buehler
    Rollins School of Public Health, Emory University, 1518 Clifton Road NE, Atlanta, GA 30322, USA
    Emerg Infect Dis 9:1197-204
  3. Histopathology and immunohistochemistry in the diagnosis of bioterrorism agents
    Jeannette Guarner
    Infectious Disease Pathology Activity, Centers for Disease Control and Prevention, Mailstop G32, 1600 Clifton Rd NE, Atlanta, GA 30333, USA
    J Histochem Cytochem 54:3-11
    ..with specific emphasis on the role of pathology and immunohistochemistry and will describe the histopathologic features of category A bioterrorism agents (anthrax, plague, tularemia, botulism, smallpox, and viral hemorrhagic fevers).
  4. Bioterrorism and catastrophe response: a quick-reference guide to resources
    Susan Z Han
    Harvard School of Dental Medicine, Boston, USA
    J Am Dent Assoc 134:745-52
    ..with the greatest potential for use as weapons: anthrax, botulism, plague, smallpox, tularemia and viral hemorrhagic fevers. This article presents Web site and journal citations for background and patient-oriented information (..
  5. Molecular diagnostic techniques for use in response to bioterrorism
    Marcia A Firmani
    Department of Clinical Laboratory Sciences, Louisiana State University Health Sciences Center, 1900 Gravier Street, New Orleans, LA 70112 2223, USA
    Expert Rev Mol Diagn 3:605-16
    ..Consequently, the molecular diagnostic techniques that have recently been developed for the diseases associated with these agents will be emphasized...
  6. Recognition and management of bioterrorism infections
    Mark L Higdon
    Family Practice Residency Program, Martin Army Community Hospital, Fort Benning, Georgia, USA
    Am Fam Physician 67:1927-34
    ..Many resources are available to physicians when a bioterrorism attack is suspected, including local public health agencies and the Centers for Disease Control and Prevention...
  7. Threats in bioterrorism. I: CDC category A agents
    Robert G Darling
    Operational Medicine Division, US Army Medical Research Institute of Infectious Diseases USAMRIID, 1425 Porter Street, ATTN MCMR UIM O, Fort Detrick, MD 21702 5011, USA
    Emerg Med Clin North Am 20:273-309
    ..Thus, it is imperative that plans be developed now to deal with the consequences of an intentional release of any one or more of these pathogens...
  8. Bioterrorism: a clinical reality
    Robert J Leggiadro
    Lincoln Medical and Mental Health Center, Bronx, NY, USA
    Pediatr Ann 36:352-8
  9. [Emerging or re-emerging infections that can be used for bioterrorism]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitié Salpêtrière, 47 83, boulevard de l Hôpital, 75013 Paris, France
    Presse Med 34:149-55
    ..INFECTIONS THAT REQUIRE RECOGNITION: The role of practitioners in the rapid recognition of bioterrorism-related infections is crucial. Hence, updated knowledge on these potentially emerging or reemerging infections is required...
  10. Biological and chemical agents: a brief synopsis
    Mark Rosenbloom
    Northwestern University School of Medicine, Chicago, IL, USA
    Am J Ther 9:5-14
    ..The information provided outlines the bare essentials needed to deal with any emergency or catastrophic event involving these agents...
  11. Defensive applications of gene transfer technology in the face of bioterrorism: DNA-based vaccines and immune targeting
    Catherine J Ackley
    Department of Pharmacology and Toxicology, Dartmouth Medical School, Hanover, NH 03755-1404, USA
    Expert Opin Biol Ther 3:1279-89
    ..While most of these strategies are not yet ready for human application, DNA-based vaccines appear to be among the most promising in the fight against bioterrorism...
  12. Anthrax, tularemia, plague, ebola or smallpox as agents of bioterrorism: recognition in the emergency room
    B A Cunha
    Infectious Disease Division, Winthrop-University Hospital, Mineola and State University of New York School of Medicine, Stony Brook, New York 11501, USA
    Clin Microbiol Infect 8:489-503
    ..The review concludes with suggestions for postexposure prophylaxis and therapy...
  13. Radiologic manifestations of potential bioterrorist agents of infection
    Loren Ketai
    Department of Radiology, University of New Mexico Health Science Center, 915 Camino de Salud N.E, Albuquerque, NM 87131-5336, USA
    AJR Am J Roentgenol 180:565-75
  14. Bioterrorism
    Theodore J Cieslak
    Department of Pediatrics, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam, Houston, TX 78234-6200, USA
    Pediatr Ann 32:154-65
  15. [Bioterrorism]
    Tetsutaro Sata
    Department of Pathology, National Institute of Infectious Diseases
    Nihon Hoigaku Zasshi 59:119-25
    ..Both medical knowledge of bioterrorism and the preparedness with training under simulation should be required in advance...
  16. [Germs employed as biological weapons]
    C G Meyer
    Anasthesiol Intensivmed Notfallmed Schmerzther 37:538-46
  17. Pathobiology and management of laboratory rodents administered CDC category A agents
    Yongqun He
    Unit for Laboratory Animal Medicine, University of Michigan Medical School, Ann Arbor, USA
    Comp Med 57:18-32
    ..virus (smallpox), Francisella tularensis (tularemia), and the filoviruses and arenaviruses that induce viral hemorrhagic fevers. These agents are regarded as having the greatest potential for adverse impact on public health and ..
  18. Recognizing the real threat of biological terror
    Richard P Wenzel
    Department of Internal Medicine, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298-0565, USA
    Trans Am Clin Climatol Assoc 113:42-53; discussion 53-5
    ..Herein I will review some of the issues and some of the currently available biological weapons. The major goal is to highlight the clinical presentations of patients with infections that could be used as biological weapons...
  19. Hemorrhagic fever viruses as biological weapons: medical and public health management
    Luciana Borio
    Johns Hopkins Center for Civilian Biodefense Strategies, Johns Hopkins Schools of Medicine and Public Health, 111 Market Pl, Suite 830, Baltimore, MD 21202, USA
    JAMA 287:2391-405
    ..Initiation of ribavirin therapy in the early phases of illness may be useful in treatment of some of these viruses, although extensive experience is lacking. There are no licensed vaccines to treat the diseases caused by HFVs...
  20. [Haemorrhagic fever viruses, possible bioterrorist use]
    Sophie Rigaudeau
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitié Salpêtrière, 47 83, boulevard de l Hôpital, 75013 Paris, France
    Presse Med 34:169-76
    ..Except for yellow fever, there is no vaccination for the other forms of viral haemorrhagic fever...
  21. Bichat guidelines for the clinical management of haemorrhagic fever viruses and bioterrorism-related haemorrhagic fever viruses
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E11-2
    ..Ribavirin is recommended for the treatment and the prophylaxis of the arenaviruses and the bunyaviruses, but is not effective for the other families. All patients must be isolated and receive intensive supportive therapy...
  22. Therapeutic options for diseases due to potential viral agents of bioterrorism
    Michael S Bronze
    Department of Medicine, University of Oklahoma Health Sciences Center, Williams Pavilion, Room WP2080, 920 Stanton Young Blvd, Oklahoma City, OK 73190, USA
    Curr Opin Investig Drugs 4:172-8
    ..Genomic analysis of the viral pathogen and the animal model response to infection may provide valuable information enabling the development of novel treatment and prevention strategies. Current knowledge of these strategies is reviewed...
  23. Hemorrhagic fevers and bioterror
    Stephen A Berger
    Department of Microbiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Isr Med Assoc J 4:513-9
  24. Hospital preparedness and management of patients affected by viral haemorrhagic fever or smallpox at the Lazzaro Spallanzani Institute, Italy
    G Ippolito
    Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Rome, Italy
    Euro Surveill 10:36-9
    ....
  25. Defending against viruses in biowarfare. How to respond to smallpox, encephalitides, hemorrhagic fevers
    Timothy M Straight
    Department of Medicine, Infectious Disease Service, Walter Reed Army Medical Center, 6800 Georgia Ave, Washington, DC 20317, USA
    Postgrad Med 112:75-6, 79-80, 85-6
    ..Awareness and preparedness are instrumental in reducing viral transmission and improving survival of the victims...
  26. Hemorrhagic fever viruses
    David C Pigott
    Department of Emergency Medicine, The University of Alabama at Birmingham, 619 South 19th Street, Birmingham, AL 35249 7013, USA
    Crit Care Clin 21:765-83, vii
    ..Important aspects of management, including recognition of infected patients, isolation and decontamination procedures, as well as available vaccines and therapies are emphasized...
  27. What caused the Black Death?
    C J Duncan
    School of Biological Sciences, University of Liverpool, UK
    Postgrad Med J 81:315-20
    ..Epidemics of haemorrhagic plague over the next three centuries then steadily raised the frequency in Europe (but not elsewhere) to present day values...
  28. Reappraisal of the historical selective pressures for the CCR5-Delta32 mutation
    S R Duncan
    Department of Engineering Science, University of Oxford, Parks Road, Oxford, UK
    J Med Genet 42:205-8
    ....
  29. Wave-like spread of Ebola Zaire
    Peter D Walsh
    Max Planck Institute for Evolutionary Primatology, Leipzig, Germany
    PLoS Biol 3:e371
    ..Controlling the impact of Ebola on wild apes and human populations may be more feasible than previously recognized...
  30. Outbreaks of filovirus hemorrhagic fever: time to refocus on the patient
    Daniel G Bausch
    Tulane School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA
    J Infect Dis 196:S136-41
    ..quot; A summary of the opportunities for and challenges to improving treatment of filovirus hemorrhagic fevers is presented here...
  31. Lessons from nosocomial viral haemorrhagic fever outbreaks
    Susan P Fisher Hoch
    Department of Epidemiology, University of Texas Houston Health Science Center, School of Public Health, Brownsville Campus, Brownsville, TX, USA
    Br Med Bull 73:123-37
    ..Educating the public to demand higher standards could be a powerful tool. Good practices are difficult to establish and maintain on the scale needed...
  32. A clinical guide to viral haemorrhagic fevers: Ebola, Marburg and Lassa
    Benjamin Jeffs
    Medicens Sans Frontieres, Spain
    Trop Doct 36:1-4
    ..This article gives a brief overview of diseases caused by the Ebola, Marburg and Lassa viruses. It gives some practical advice to the clinician on the diagnosis and management of these diseases...
  33. Imported viral haemorrhagic fever with a potential for person-to-person transmission: review and recommendations for initial management of a suspected case in Belgium
    R Colebunders
    Departement Klinische Wetenschappen, Instituut voor Tropische Geneeskunde Nationalestraat 155, B 2000 Antwerpen
    Acta Clin Belg 57:233-40
    ..Using universal precautions for handling blood and body fluids and barrier nursing techniques there is little risk that if a patient with viral haemorrhagic fever arrives in Belgium there will be secondary cases...
  34. Persistence of category A select agents in the environment
    Ryan Sinclair
    Department of Soil, Water and Environmental Science, University of Arizona, Tucson, Arizona 85721, USA
    Appl Environ Microbiol 74:555-63
  35. Mitogen therapy for biological warfare/terrorist attacks and viral hemorrhagic fever control
    Bruce M Wimer
    Cancer Biother Radiopharm 17:19-28
    ..A key objective would be to find an effective management for the dreaded viral hemorrhagic fevers. Using Ebola infection as an experimental model, Yang et al...
  36. [Viral hemorrhagic fever as a biological weapon]
    Eyal Robenshtok
    Harefuah 141:96-9, 119
    ..This paper reviews the viruses that cause hemorrhagic fever, and their role as possible warfare agents...
  37. The potential role of viral pathogens as agents of bioterrorism
    Michael S Bronze
    Department of Medicine, University of Oklahoma Health Sciences Center, Room WP2080, 920 Stanton Young Blvd, Oklahoma City, OK 73190, USA
    J Okla State Med Assoc 96:29-33
  38. Viral hemorrhagic fevers
    Aileen M Marty
    Battelle Memorial Institute, Suite 601, 1550 Crystal Drive, Arlington, VA 22202 4172, USA
    Clin Lab Med 26:345-86, viii
    ..While significant progress has been made over the last several years in dissecting out the molecular biology and pathogenesis of the HF viruses, there are currently no vaccines or drugs licensed available for most of the VHFs...
  39. Modes of transmission of hemorrhagic fever
    Leonard J Morse
    JAMA 288:571; author reply 571
  40. [Biological weapons. II. Smallpox, botulinum toxin, hemorrhagic fever viruses]
    Wolfram Christ
    Med Monatsschr Pharm 26:13-22
  41. Biological warfare and the skin II: viruses
    Theodore J Cieslak
    San Antonio Military Pediatric Center, San Antonio, Texas, USA
    Clin Dermatol 20:355-64
  42. [Dengue and other hemorrhagic viral fevers]
    Cristina Domingo Carrasco
    Laboratorio de Arbovirus y Enfermedades Víricas Importadas, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Madrid, Spain
    Enferm Infecc Microbiol Clin 23:615-26
    Few diseases generate such alarm among the general population and health professionals as viral hemorrhagic fevers (VHFs)...
  43. The role of reverse genetics systems in studying viral hemorrhagic fevers
    Hideki Ebihara
    Division of Virology, Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, Japan
    Thromb Haemost 94:240-53
    ..Here we review the existing reverse genetics systems for VHF causing viruses and discuss their use in studying viral replication, pathogenesis, and the development of antivirals and vaccines...
  44. [The use of monoclonal antibodies in studying the causative agents of viral hemorrhagic fevers]
    G V Borisevich
    Vopr Virusol 48:4-8
    ..The methodological specificity of obtaining the Mabs to viral hemorrhagic-fevers' agents as well as data on its practical use are discussed...
  45. Infectious disease surveillance update
    Pam Das
    Lancet Infect Dis 2:133
  46. [Hemorrhagic (Marburg, Ebola, Lassa, and Bolivian) fevers: epidemiology, clinical pictures, and treatment]
    I V Borisevich
    Vopr Virusol 51:8-16
    ..Particular emphasis is laid on the methods for infection diagnosis and on the studies to design specific protective agents--immunoglobulins and inactivated vaccines...
  47. Alkhumra virus infection, a new viral hemorrhagic fever in Saudi Arabia
    Tariq A Madani
    Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
    J Infect 51:91-7
    ..The role of arthropods such as ticks and mosquitoes, and animals such as sheep, goat, and rodents in the transmission and maintenance of the virus remains to be elucidated...
  48. A reassortant bunyavirus isolated from acute hemorrhagic fever cases in Kenya and Somalia
    M D Bowen
    Special Pathogens Branch, Divivion of Viral and Ricksettial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA 30333, USA
    Virology 291:185-90
    ..The association of this reassortant bunyavirus, proposed name Garissa virus, with severe disease is supported by the detection of the virus RNA in acute-phase sera taken from 12 additional hemorrhagic fever cases in the region...
  49. [Infectiology -- new scenarios, ever increasing tasks]
    W V Kern
    Zentrum Infektiologie und Reisemedizin, Medizinische Klinik und Poliklinik, Universitätsklinikum, Freiburg
    Dtsch Med Wochenschr 130:1559-62
  50. [Risk of nosocomial infection in intertropical Africa--part 2: patient infection]
    F Simon
    Service de Pathologie Infectieuse et Tropicale, l Hôpital d instruction des armées Laveran, Marseilles Armées
    Med Trop (Mars) 67:197-203
    ..Epidemics involving viral hemorrhagic fever are rare but highly publicized events that attest to daily neglect of nosocomial risk factors in some health care facilities..
  51. Drought, epidemic disease, and the fall of classic period cultures in Mesoamerica (AD 750-950). Hemorrhagic fevers as a cause of massive population loss
    Rodolfo Acuna Soto
    Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, México City, D F C P 04510, Mexico
    Med Hypotheses 65:405-9
    ....
  52. Ngari virus is a Bunyamwera virus reassortant that can be associated with large outbreaks of hemorrhagic fever in Africa
    Sonja R Gerrard
    Special Pathogens Branch, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd. NE, Atlanta, GA 30333, USA
    J Virol 78:8922-6
    ..Ngari virus should be considered when investigating hemorrhagic fever outbreaks throughout sub-Saharan Africa...
  53. Treating viral hemorrhagic fever
    Albert T A Mairuhu
    Slotervaart Hospital, Department of Internal Medicine, Louwesweg 6, 1066 EC Amsterdam, The Netherlands
    IDrugs 6:1061-6
    b>Viral hemorrhagic fevers are illnesses associated with a number of geographically restricted, mostly tropical areas. Over recent decades a number of new hemorrhagic fever viruses have emerged...
  54. Megadrought and megadeath in 16th century Mexico
    Rodolfo Acuna-Soto
    Universidad Nacional Autonoma de Mexico, Ciudad Universitaria, Mexico
    Emerg Infect Dis 8:360-2
    ....
  55. Ebola-Poe: a modern-day parallel of the red death?
    Setu K Vora
    Emerg Infect Dis 8:1521-3
  56. The model of response to viral haemorrhagic fevers of the National Institute for Infectious Diseases "Lazzaro Spallanzani"
    O Armignacco
    National Institute for Infectious Diseases Lazzaro Spallanzani-IRCCS, Rome, Italy
    J Biol Regul Homeost Agents 15:314-21
    ..A brief overview of procedures and equipment adopted is provided...