reoviridae infections

Summary

Summary: Infections produced by reoviruses, general or unspecified.

Top Publications

  1. Kant A, Balk F, Born L, van Roozelaar D, Heijmans J, Gielkens A, et al. Classification of Dutch and German avian reoviruses by sequencing the sigma C protein. Vet Res. 2003;34:203-12 pubmed
    ..We did not establish temporal or geographic differences in the avian reoviruses studied...
  2. Vasserman Y, Eliahoo D, Hemsani E, Kass N, Ayali G, Pokamunski S, et al. The influence of reovirus sigma C protein diversity on vaccination efficiency. Avian Dis. 2004;48:271-8 pubmed
    ..The results of this study highlight the need to reconsider vaccinations against ARV in terms of the strains to be used and of the method of identifying protective antibodies transferred to progeny...
  3. Van de Zande S, Kuhn E. Central nervous system signs in chickens caused by a new avian reovirus strain: a pathogenesis study. Vet Microbiol. 2007;120:42-9 pubmed
    ..The results indicate that the pathogenesis of ERS infection in chickens bears some resemblance with that of the mammalian reoviruses serotype 1 in mice...
  4. Guo K, Dormitorio T, Ou S, Giambrone J. Detection and differentiation of avian reoviruses using SYBR-Green I-based two-step real-time reverse transcription PCR with melting curve analysis. Avian Dis. 2012;56:369-76 pubmed
    ..Compared with traditional subtyping methods, the current melting curve analysis provided an accurate test for separating ARVs, thereby making it a useful method for the improved selection of ARV vaccines...
  5. Oura C, Batten C, Ivens P, Balcha M, Alhassan A, Gizaw D, et al. Equine encephalosis virus: evidence for circulation beyond southern Africa. Epidemiol Infect. 2012;140:1982-6 pubmed
    ..This evidence for EEV circulation in countries in East and West Africa sheds light on how the virus may have reached Israel to cause the recent outbreak in 2009...
  6. Mohd Jaafar F, Attoui H, de Micco P, de Lamballerie X. Recombinant VP6-based enzyme-linked immunosorbent assay for detection of immunoglobulin G antibodies to Eyach virus (genus Coltivirus). J Clin Virol. 2004;30:248-53 pubmed
    ..It was isolated in Germany and France and has been suspected to be responsible for neurological diseases in humans. To date, there has been no relatively rapid and relatively specific serological assay for EYAV...
  7. Martins L, Diniz J, Silva E, Barros V, Monteiro H, Azevedo R, et al. Characterization of Minaçu virus (Reoviridae: Orbivirus) and pathological changes in experimentally infected newborn mice. Int J Exp Pathol. 2007;88:63-73 pubmed
    ..The liver, spleen and kidneys had moderate tissue changes. Viral antigens were more abundant in the CNS and the heart, and absent in the lungs. In conclusion, Minaçu virus belongs to the family Reoviridae, genus Orbivirus...
  8. Yang Z, Wang C, Lee L, Chuang K, Lien Y, Yin H, et al. Development of ELISA kits for antibodies against avian reovirus using the sigmaC and sigmaB proteins expressed in the methyltropic yeast Pichia pastoris. J Virol Methods. 2010;163:169-74 pubmed publisher
    ..The results revealed that the correlation rates for the serum neutralization titer and the absorbance values with the new ELISA kits and the conventional ELISA were 100% and 95.8%, respectively...
  9. Boehme K, Frierson J, Konopka J, Kobayashi T, Dermody T. The reovirus sigma1s protein is a determinant of hematogenous but not neural virus dissemination in mice. J Virol. 2011;85:11781-90 pubmed publisher
    ..Together, these results indicate that ?1s is not required for reovirus spread by neural mechanisms. Instead, ?1s mediates hematogenous dissemination within the infected host, which is required for full reovirus neurovirulence...

More Information

Publications62

  1. Danthi P, Kobayashi T, Holm G, Hansberger M, Abel T, Dermody T. Reovirus apoptosis and virulence are regulated by host cell membrane penetration efficiency. J Virol. 2008;82:161-72 pubmed
    ..These results indicate a critical function for the membrane penetration activity of mu1 in evoking prodeath signaling pathways that regulate reovirus pathogenesis...
  2. Kobayashi T, Antar A, Boehme K, Danthi P, Eby E, Guglielmi K, et al. A plasmid-based reverse genetics system for animal double-stranded RNA viruses. Cell Host Microbe. 2007;1:147-57 pubmed
    ..The plasmid-based reverse genetics approach described here can be exploited for studies of reovirus replication and pathogenesis and used to develop reovirus as a vaccine vector...
  3. O Donnell S, Holm G, Pierce J, Tian B, Watson M, Chari R, et al. Identification of an NF-kappaB-dependent gene network in cells infected by mammalian reovirus. J Virol. 2006;80:1077-86 pubmed
    ..Together, these results suggest a genetic program for reovirus-induced apoptosis involving NF-kappaB-directed expression of cellular genes that activate death signaling pathways in infected cells...
  4. Belhouchet M, Mohd Jaafar F, Firth A, Grimes J, Mertens P, Attoui H. Detection of a fourth orbivirus non-structural protein. PLoS ONE. 2011;6:e25697 pubmed publisher
    ..NS4 of both GIV and BTV protect DNA from degradation by DNAse. NS4 was found to associate with lipid droplets in cells infected with BTV or GIV or transfected with a plasmid expressing NS4. ..
  5. Barton E, Youree B, Ebert D, Forrest J, Connolly J, Valyi Nagy T, et al. Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease. J Clin Invest. 2003;111:1823-33 pubmed
  6. Swanson G, Meyers J, Huang D. Restricted growth of avirulent avian reovirus strain 2177 in macrophage derived HD11 cells. Virus Res. 2001;81:103-11 pubmed
    ..These features may contribute to the lower virulence of the strain 2177 in their natural host in vivo...
  7. Anthony S, Maan N, Maan S, Sutton G, Attoui H, Mertens P. Genetic and phylogenetic analysis of the core proteins VP1, VP3, VP4, VP6 and VP7 of epizootic haemorrhagic disease virus (EHDV). Virus Res. 2009;145:187-99 pubmed publisher
    ..Interestingly, VP6 did not show this, and possible reasons for this are discussed...
  8. Nabeshima T, Thi Nga P, Guillermo P, Parquet M, Yu F, Thanh Thuy N, et al. Isolation and molecular characterization of Banna virus from mosquitoes, Vietnam. Emerg Infect Dis. 2008;14:1276-9 pubmed publisher
    ..Together, these findings suggest widespread distribution of this virus throughout Southeast Asia...
  9. Temizel E, Yesilbag K, Batten C, Senturk S, Maan N, Mertens P, et al. Epizootic hemorrhagic disease in cattle, Western Turkey. Emerg Infect Dis. 2009;15:317-9 pubmed
    ..Reverse transcription-PCR and sequence analyses indicated that the virus belonged to EHD virus serotype 6, thus confirming EHD virus infection of cattle in Turkey. ..
  10. Day J. The diversity of the orthoreoviruses: molecular taxonomy and phylogentic divides. Infect Genet Evol. 2009;9:390-400 pubmed publisher
    ..This review mainly focuses on the molecular taxonomy of the fusogenic orthoreoviruses, and aims to provide insight into their relationships with the non-fusogenic orthoreoviruses and other selected Reoviridae genera...
  11. Thirukkumaran C, Morris D. Oncolytic viral therapy using reovirus. Methods Mol Biol. 2009;542:607-34 pubmed publisher
    ..The extensive pre-clinical efficacy, replication competency, and low toxicity profile in humans has placed the reovirus as an attractive anti-cancer therapeutic for ongoing clinical testing...
  12. Tai J, Williams J, Edwards K, Wright P, Crowe J, Dermody T. Prevalence of reovirus-specific antibodies in young children in Nashville, Tennessee. J Infect Dis. 2005;191:1221-4 pubmed
    ..We observed an age-dependent increase in reovirus-specific antibodies in children 1 year of age and older, peaking at 50.0% in children 5-6 years of age. These findings suggest that reovirus infections are common during early childhood...
  13. Tyler K, Barton E, Ibach M, Robinson C, Campbell J, O Donnell S, et al. Isolation and molecular characterization of a novel type 3 reovirus from a child with meningitis. J Infect Dis. 2004;189:1664-75 pubmed
    ..T3C/96 is capable of systemic spread in newborn mice after peroral inoculation and produces lethal encephalitis. These results suggest that serotype 3 reoviruses can cause meningitis in humans...
  14. Wittmann E, Mello P, Baylis M. Effect of temperature on the transmission of orbiviruses by the biting midge, Culicoides sonorensis. Med Vet Entomol. 2002;16:147-56 pubmed
    ..sonorensis for AHSV4, EHDV1, BTV10 and BTV16 was greater at higher temperatures, because although vector survival was reduced, this was more than compensated for by the accompanying decrease in duration of the EIP...
  15. Nygaard R, Golden J, Schiff L. Impact of host proteases on reovirus infection in the respiratory tract. J Virol. 2012;86:1238-43 pubmed publisher
    ..In this report, we show that endogenous respiratory and inflammatory proteases can promote reovirus infection in vitro and that preexisting inflammation augments in vivo infection in the murine respiratory tract...
  16. Hassler D, Oehme R, Kimmig P, Dobler G. [Eyach virus: relative of the Colorado tick fever virus rediscovered in Baden-Württemberg]. Dtsch Med Wochenschr. 2003;128:1874 pubmed
  17. Antar A, Konopka J, Campbell J, Henry R, Perdigoto A, Carter B, et al. Junctional adhesion molecule-A is required for hematogenous dissemination of reovirus. Cell Host Microbe. 2009;5:59-71 pubmed publisher
    ..These findings indicate that a broadly expressed IgSF viral receptor specifically mediates hematogenous dissemination in the host...
  18. Zhang Y, Liu M, Shuidong O, Hu Q, Guo D, Chen H, et al. Detection and identification of avian, duck, and goose reoviruses by RT-PCR: goose and duck reoviruses are part of the same genogroup in the genus Orthoreovirus. Arch Virol. 2006;151:1525-38 pubmed
    ..Overall, this study developed a sensitive and specific technique for the identification ARV, DRV, and GRV, and sequencing analysis has enhanced our understanding of the evolutionary relationship between ARV, DRV, and GRV...
  19. Connolly J, Dermody T. Virion disassembly is required for apoptosis induced by reovirus. J Virol. 2002;76:1632-41 pubmed
    ..These results demonstrate that disassembly of reovirus virions to form ISVPs, but not viral transcription or subsequent steps in viral replication, is required for reovirus to induce apoptosis...
  20. Derrien M, Fields B. Anti-interleukin-3 and anti-nerve growth factor increase neonatal mice survival to reovirus type 3 clone 9 per oral challenge. J Neuroimmunol. 2000;110:209-13 pubmed
    ..These data suggest that IL-3 and NGF are involved in the pathogenesis of T3C9 infection in neonatal mice...
  21. Hamamdzic D, Phillips Dorsett T, Altman Hamamdzic S, London S, London L. Reovirus triggers cell type-specific proinflammatory responses dependent on the autocrine action of IFN-beta. Am J Physiol Lung Cell Mol Physiol. 2001;280:L18-29 pubmed
  22. Kobayashi T, Ooms L, Ikizler M, Chappell J, Dermody T. An improved reverse genetics system for mammalian orthoreoviruses. Virology. 2010;398:194-200 pubmed publisher
    ..Improvements to the reovirus reverse genetics system enhance its applicability for studies of reovirus biology and clinical use...
  23. Savini G, Afonso A, Mellor P, Aradaib I, Yadin H, Sanaa M, et al. Epizootic heamorragic disease. Res Vet Sci. 2011;91:1-17 pubmed publisher
    ..It is our conviction that more attention should be drawn to both EHDV and the disease itself in order to fulfil all these gaps and not to be unprepared in case future possible incursions...
  24. Beckham J, Goody R, Clarke P, Bonny C, Tyler K. Novel strategy for treatment of viral central nervous system infection by using a cell-permeating inhibitor of c-Jun N-terminal kinase. J Virol. 2007;81:6984-92 pubmed
    ..Given the efficacy of the inhibitor in protecting mice from viral encephalitis, JNK inhibition represents a promising and novel treatment strategy for viral encephalitis...
  25. Middleton J, Agosto M, Severson T, Yin J, Nibert M. Thermostabilizing mutations in reovirus outer-capsid protein mu1 selected by heat inactivation of infectious subvirion particles. Virology. 2007;361:412-25 pubmed
    ..We propose that the mutants stabilize the outer capsid by interfering with unwinding of the mu1 trimer...
  26. Attoui H, Mohd Jaafar F, Biagini P, Cantaloube J, De Micco P, Murphy F, et al. Genus Coltivirus (family Reoviridae): genomic and morphologic characterization of Old World and New World viruses. Arch Virol. 2002;147:533-61 pubmed
    ..This analysis allows for the first time to propose an evolutionary rate for virus dsRNA genomes which was found to be in the order of 10(-8) to 10(-9) mutations/nt/year, a rate similar to that of dsDNA genomes...
  27. Mohd Jaafar F, Attoui H, Gallian P, Isahak I, Wong K, Cheong S, et al. Recombinant VP9-based enzyme-linked immunosorbent assay for detection of immunoglobulin G antibodies to Banna virus (genus Seadornavirus). J Virol Methods. 2004;116:55-61 pubmed
    ..The VP9 ELISA permits to determine the sero-status of a population without special safety precautions and without any requirements to propagate the BAV. This test should be a useful tool for epidemiological survey of BAV...
  28. O Donnell S, Hansberger M, Connolly J, Chappell J, Watson M, Pierce J, et al. Organ-specific roles for transcription factor NF-kappaB in reovirus-induced apoptosis and disease. J Clin Invest. 2005;115:2341-50 pubmed
    ..These findings reveal an organ-specific role for NF-kappaB in the regulation of reovirus-induced apoptosis, which modulates encephalitis and myocarditis associated with reovirus infection...
  29. London L, Majeski E, Paintlia M, Harley R, London S. Respiratory reovirus 1/L induction of diffuse alveolar damage: a model of acute respiratory distress syndrome. Exp Mol Pathol. 2002;72:24-36 pubmed
    ..Reovirus 1/L infection of CBA/J mice will allow investigations of the pathophysiology of ARDS as it progresses from the initial stages of edema and neutrophilia to fibrotic lesion development in late stages...
  30. Gaydos J, Davidson W, Elvinger F, Mead D, Howerth E, Stallknecht D. Innate resistance to epizootic hemorrhagic disease in white-tailed deer. J Wildl Dis. 2002;38:713-9 pubmed
    ..Should this phenomenon occur in other species, these findings have major implications for managing wildlife populations, both endangered and non-endangered, using tools such as translocation and captive propagation...
  31. Golden J, Bahe J, Lucas W, Nibert M, Schiff L. Cathepsin S supports acid-independent infection by some reoviruses. J Biol Chem. 2004;279:8547-57 pubmed
  32. B nyai K, Dand r E, Dorsey K, Mat T, Palya V. The genomic constellation of a novel avian orthoreovirus strain associated with runting-stunting syndrome in broilers. Virus Genes. 2011;42:82-9 pubmed publisher
    ..Collectively, our analyses indicated that multiple reassortment events and strong divergence caused by the accumulation of point mutations could have led to the observed assortment and genetic heterogeneity of the AVS-B genome...
  33. Prestwich R, Errington F, Steele L, Ilett E, Morgan R, Harrington K, et al. Reciprocal human dendritic cell-natural killer cell interactions induce antitumor activity following tumor cell infection by oncolytic reovirus. J Immunol. 2009;183:4312-21 pubmed publisher
    ..These findings suggest that reciprocal DC-NK cell interactions, following reovirus therapy, may play an important role in altering the immune milieu of the tumor microenvironment and mediating tumor regression...
  34. Helander A, Miller C, Myers K, Neutra M, Nibert M. Protective immunoglobulin A and G antibodies bind to overlapping intersubunit epitopes in the head domain of type 1 reovirus adhesin sigma1. J Virol. 2004;78:10695-705 pubmed
    ..Identification of these intersubunit epitopes on sigma1 opens the way for further studies of the mechanisms of antibody-based neutralization and protection with type 1 reoviruses...
  35. Attoui H, Mohd Jaafar F, Belhouchet M, Aldrovandi N, Tao S, Chen B, et al. Yunnan orbivirus, a new orbivirus species isolated from Culex tritaeniorhynchus mosquitoes in China. J Gen Virol. 2005;86:3409-17 pubmed publisher
    ..The availability of the complete genome sequence will facilitate the development of sequence-specific PCR assays for the study of YUOV epidemiology in the field...
  36. Zhang Y, Jiang J, Chen Y, Zhu R, Shi Y, Zhang Q, et al. The innate immune response to grass carp hemorrhagic virus (GCHV) in cultured Carassius auratus blastulae (CAB) cells. Dev Comp Immunol. 2007;31:232-43 pubmed
    ..This study provides strong evidence for existence of IFN antiviral innate immune response in fish, and will assist in elucidating the origin and evolution of vertebrate IFN system...
  37. Prestwich R, Errington F, Ilett E, Morgan R, Scott K, Kottke T, et al. Tumor infection by oncolytic reovirus primes adaptive antitumor immunity. Clin Cancer Res. 2008;14:7358-66 pubmed publisher
    ..Early clinical trials are under way exploring the direct oncolytic potential of reovirus. This study addresses whether tumor infection by reovirus is also able to generate bystander, adaptive antitumor immunity...
  38. Holm G, Zurney J, Tumilasci V, Leveille S, Danthi P, Hiscott J, et al. Retinoic acid-inducible gene-I and interferon-beta promoter stimulator-1 augment proapoptotic responses following mammalian reovirus infection via interferon regulatory factor-3. J Biol Chem. 2007;282:21953-61 pubmed
    ..Interferon-beta promoter stimulator-1 and IRF-3 are required for efficient apoptosis following reovirus infection, suggesting a common mechanism of antiviral cytokine induction and activation of the cell death response...
  39. Hermann L, Embree J, Hazelton P, Wells B, Coombs R. Reovirus type 2 isolated from cerebrospinal fluid. Pediatr Infect Dis J. 2004;23:373-5 pubmed
    ..Virus neutralization and RNA-gel electrophoresis studies identified the isolated pathogen as reovirus serotype 2. This report represents one of only a few to isolate reovirus from the central nervous system in humans...
  40. Mikalsen A, Haugland O, Rode M, Solbakk I, Evensen O. Atlantic salmon reovirus infection causes a CD8 T cell myocarditis in Atlantic salmon (Salmo salar L.). PLoS ONE. 2012;7:e37269 pubmed publisher
    ..We further demonstrate mRNA transcript assessment and in situ characterization that challenged fish develop a CD8+ T cell myocarditis...
  41. Li L, Sevinsky J, Rowland M, Bundy J, Stephenson J, Sherry B. Proteomic analysis reveals virus-specific Hsp25 modulation in cardiac myocytes. J Proteome Res. 2010;9:2460-71 pubmed publisher
    ..However, results here provide the first evidence for a virus-induced decrease in Hsp25/27 and suggest that viruses may have evolved a mechanism to subvert this protective response, as they have for IFN...
  42. Zhang C, Wang Q, Shi C, Zeng W, Liu Y, Wu S. Molecular analysis of grass carp reovirus HZ08 genome segments 1-3 and 5-6. Virus Genes. 2010;41:102-4 pubmed publisher
  43. Kedmi M, van Straten M, Ezra E, Galon N, Klement E. Assessment of the productivity effects associated with epizootic hemorrhagic disease in dairy herds. J Dairy Sci. 2010;93:2486-95 pubmed publisher
    ..5/cow in the Israeli dairy cattle. This equals 0.55% of the average total value production of a dairy cow in Israel. This is the first study to estimate the production losses caused by EHDV or any bluetongue-like disease...
  44. Lin Y, Lee L, Shih W, Hu Y, Liu H. Baculovirus surface display of sigmaC and sigmaB proteins of avian reovirus and immunogenicity of the displayed proteins in a mouse model. Vaccine. 2008;26:6361-7 pubmed publisher
    ..This demonstrates that the recombinant baculoviruses BacSC-sigmaC and BacSC-sigmaB can be a potential vaccine against ARV infections...
  45. Mohd Jaafar F, Attoui H, Mertens P, de Micco P, de Lamballerie X. Structural organization of an encephalitic human isolate of Banna virus (genus Seadornavirus, family Reoviridae). J Gen Virol. 2005;86:1147-57 pubmed
  46. Ruder M, Allison A, Stallknecht D, Mead D, McGraw S, Carter D, et al. Susceptibility of white-tailed deer (Odocoileus virginianus) to experimental infection with epizootic hemorrhagic disease virus serotype 7. J Wildl Dis. 2012;48:676-85 pubmed
  47. Løvoll M, Wiik Nielsen J, Grove S, Wiik Nielsen C, Kristoffersen A, Faller R, et al. A novel totivirus and piscine reovirus (PRV) in Atlantic salmon (Salmo salar) with cardiomyopathy syndrome (CMS). Virol J. 2010;7:309 pubmed publisher
    ..In the present work we have studied whether PRV or other infectious agents may be involved in the etiology of CMS...
  48. Attoui H, Mohd Jaafar F, de Micco P, de Lamballerie X. Coltiviruses and seadornaviruses in North America, Europe, and Asia. Emerg Infect Dis. 2005;11:1673-9 pubmed
    ..Evidence suggests that BAV is responsible for encephalitis in humans. Infection with BAV may be underreported because it circulates in regions with a high incidence of Japanese encephalitis and could be misdiagnosed as this disease...
  49. Cheng P, Lau C, Lai A, Ho E, Leung P, Chan F, et al. A novel reovirus isolated from a patient with acute respiratory disease. J Clin Virol. 2009;45:79-80 pubmed publisher
  50. Franca M, Crespo R, Chin R, Woolcock P, Shivaprasad H. Retrospective study of myocarditis associated with reovirus in turkeys. Avian Dis. 2010;54:1026-31 pubmed
    ..Reovirus has been suggested as a probable etiology of this condition. Vitamin E deficiency might also contribute to the development of the lesions...
  51. Hollmen T, Franson J, Kilpi M, Docherty D, Hansen W, Hario M. Isolation and characterization of a reovirus from common eiders (Somateria mollissima) from Finland. Avian Dis. 2002;46:478-84 pubmed
    ..These findings raise the question of potential involvement of the virus in poor duckling survival and eider population declines observed in several breeding areas along coastal Finland since the mid-1980s...
  52. Kedmi M, Herziger Y, Galon N, Cohen R, Perel M, Batten C, et al. The association of winds with the spread of EHDV in dairy cattle in Israel during an outbreak in 2006. Prev Vet Med. 2010;96:152-60 pubmed publisher
    ..This study therefore shows that winds are probably a major contributory factor for long and medium distance spread of Culicoides borne viruses in this region...
  53. Danthi P, Coffey C, Parker J, Abel T, Dermody T. Independent regulation of reovirus membrane penetration and apoptosis by the mu1 phi domain. PLoS Pathog. 2008;4:e1000248 pubmed publisher
    ..These results indicate that the phi domain of mu1 plays an important regulatory role in reovirus-induced apoptosis and disease...