picornaviridae infections

Summary

Summary: Virus diseases caused by the PICORNAVIRIDAE.

Top Publications

  1. Kuo C, Lim S, King N, Bartlett N, Walton R, Zhu J, et al. Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo. Respirology. 2011;16:367-77 pubmed publisher
    ..Viral infections may promote the development of asthma and are the most common causes of asthma exacerbations. We evaluated whether rhinovirus (RV) infection induces airway remodelling, as assessed by ECM deposition...
  2. Fuji N, Suzuki A, Lupisan S, Sombrero L, Galang H, Kamigaki T, et al. Detection of human rhinovirus C viral genome in blood among children with severe respiratory infections in the Philippines. PLoS ONE. 2011;6:e27247 pubmed publisher
    ..This finding suggests that the 5'NCR region may be associated with viremia...
  3. Reuter G, Nemes C, Boros A, Kapusinszky B, Delwart E, Pankovics P. Porcine kobuvirus in wild boars (Sus scrofa). Arch Virol. 2013;158:281-2 pubmed publisher
    ..Wild boars could be an important host and reservoir for kobuvirus...
  4. Tapparel C, Cordey S, Junier T, Farinelli L, Van Belle S, Soccal P, et al. Rhinovirus genome variation during chronic upper and lower respiratory tract infections. PLoS ONE. 2011;6:e21163 pubmed publisher
  5. Han X, Zhang W, Xue Y, Shao S. Sequence analysis reveals mosaic genome of Aichi virus. Virol J. 2011;8:390 pubmed publisher
    ..Although only six complete genomes of Aichi virus were deposited in GenBank at present, mosaic genomes can be found in strains from different countries...
  6. Ljubin Sternak S, Juretić E, Santak M, Pleša M, Forcic D, Vilibic Cavlek T, et al. Clinical and molecular characterization of a parechovirus type 1 outbreak in neonates in Croatia. J Med Virol. 2011;83:137-41 pubmed publisher
    ..Change of the dominant strains each year may suggest antigenic variation as a result of viral response to specific immunity of the target population...
  7. Honkavuori K, Shivaprasad H, Briese T, Street C, Hirschberg D, Hutchison S, et al. Novel picornavirus in Turkey poults with hepatitis, California, USA. Emerg Infect Dis. 2011;17:480-7 pubmed publisher
    ..Molecular, anatomic, and immunologic evidence suggests that TVH is caused by a novel picornavirus, tentatively named turkey hepatitis virus...
  8. Selvarangan R, Nzabi M, Selvaraju S, Ketter P, Carpenter C, Harrison C. Human parechovirus 3 causing sepsis-like illness in children from midwestern United States. Pediatr Infect Dis J. 2011;30:238-42 pubmed publisher
    ..We sought to determine the prevalence of HPeV CNS infections and clinical presentation in children from the United States...
  9. Cao W, Zheng H, Zhang K, Jin Y, Lv L, Yang F, et al. Complete genome sequence of the porcine kobuvirus variant CH/HNXX-4/2012. J Virol. 2012;86:11947 pubmed publisher
    ..This will help the phenotypic variation and evolutionary characteristics of porcine kobuvirus to be understood...

More Information

Publications62

  1. Cordey S, Junier T, Gerlach D, Gobbini F, Farinelli L, Zdobnov E, et al. Rhinovirus genome evolution during experimental human infection. PLoS ONE. 2010;5:e10588 pubmed publisher
    ..In vivo, HRV generate new variants rapidly during the course of an acute infection due to mutations that accumulate in hot spot regions located at the capsid level, as well as in 2C and 3C genes...
  2. Barry A, Ribeiro J, Alfieri A, van der Poel W, Alfieri A. First detection of kobuvirus in farm animals in Brazil and the Netherlands. Infect Genet Evol. 2011;11:1811-4 pubmed publisher
    ..The data presented in this study contribute to the comprehension of kobuvirus epidemiology and also to the molecular identification of kobuvirus strains circulating worldwide...
  3. Zhong H, Lin Y, Su L, Cao L, Xu M, Xu J. Prevalence of human parechoviruses in central nervous system infections in children: a retrospective study in Shanghai, China. J Med Virol. 2013;85:320-6 pubmed publisher
    ..This study provided data on the molecular epidemiology of HPeV infections in CNS-related diseases in Shanghai, China and suggest that the screening for HPeV by PCR should be included in the routine viral testing of CSF...
  4. Wang C, Lan D, Cui L, Yang Z, Yuan C, Hua X. Molecular characterization of a porcine kobuvirus strain in China. Arch Virol. 2012;157:573-8 pubmed publisher
    ..This study further confirmed the existence of multiple lineages of porcine kobuvirus and indicated that homologous recombination may be a driving force in its evolution...
  5. Hewson C, Haas J, Bartlett N, Message S, Laza Stanca V, Kebadze T, et al. Rhinovirus induces MUC5AC in a human infection model and in vitro via NF-?B and EGFR pathways. Eur Respir J. 2010;36:1425-35 pubmed publisher
    ..Revealing the complex serial signalling cascade involved identifies targets for development of pharmacologic intervention to treat mucus hypersecretion in RV-induced illness...
  6. Van Ly D, Faiz A, Jenkins C, Crossett B, Black J, McParland B, et al. Characterising the mechanism of airway smooth muscle ?2 adrenoceptor desensitization by rhinovirus infected bronchial epithelial cells. PLoS ONE. 2013;8:e56058 pubmed publisher
    ..It was deduced that the mechanism by which ?2 adrenoceptor desensitization occurs was by pattern recognition receptor activation of COX-2 induced prostaglandins...
  7. Chieochansin T, Vichiwattana P, Korkong S, Theamboonlers A, Poovorawan Y. Molecular epidemiology, genome characterization, and recombination event of human parechovirus. Virology. 2011;421:159-66 pubmed publisher
    ..In conclusion, HPeV can be detected in both the respiratory and GI tract. Moreover, HPeV which circulates in Thailand is highly diverse and subject to recombination...
  8. Drexler J, Baumgarte S, de Souza Luna L, Eschbach Bludau M, Lukashev A, Drosten C. Aichi virus shedding in high concentrations in patients with acute diarrhea. Emerg Infect Dis. 2011;17:1544-8 pubmed publisher
    ..High concentrations of up to 1.32 × 1012 RNA copies/g stool were found in 10 (2.0%) of 499 outpatients sampled in northern Germany, 2004. These data substantiate Aichi virus pathogenicity in humans...
  9. Harvala H, McLeish N, Kondracka J, McIntyre C, McWilliam Leitch E, Templeton K, et al. Comparison of human parechovirus and enterovirus detection frequencies in cerebrospinal fluid samples collected over a 5-year period in edinburgh: HPeV type 3 identified as the most common picornavirus type. J Med Virol. 2011;83:889-96 pubmed publisher
    ..The highly sensitive virus typing methods applied in this study will assist further EV and HPeV screening of sepsis and meningitis cases as well as in future molecular epidemiological studies and population surveillance...
  10. Li L, Pesavento P, Shan T, Leutenegger C, Wang C, Delwart E. Viruses in diarrhoeic dogs include novel kobuviruses and sapoviruses. J Gen Virol. 2011;92:2534-41 pubmed publisher
    ..These results highlight the high frequency of new virus detection possible even in extensively studied animal species using metagenomics approaches, and provide viral genomes for further disease-association studies...
  11. Winther B. Rhinovirus infections in the upper airway. Proc Am Thorac Soc. 2011;8:79-89 pubmed publisher
    ..Most research has been done in young healthy adults with self-limiting experimental and natural rhinovirus infections, and this may set the stage for understanding rhinovirus infections in the ear, sinus, and lower airways...
  12. Cakebread J, Xu Y, Grainge C, Kehagia V, Howarth P, Holgate S, et al. Exogenous IFN-? has antiviral and anti-inflammatory properties in primary bronchial epithelial cells from asthmatic subjects exposed to rhinovirus. J Allergy Clin Immunol. 2011;127:1148-54.e9 pubmed publisher
  13. de Almeida M, Zerbinati R, Tateno A, Oliveira C, Romao R, Rodrigues J, et al. Rhinovirus C and respiratory exacerbations in children with cystic fibrosis. Emerg Infect Dis. 2010;16:996-9 pubmed publisher
    ..A significant association was found between the presence of human rhinovirus C and respiratory exacerbations...
  14. Guilbert T, Singh A, Danov Z, Evans M, Jackson D, Burton R, et al. Decreased lung function after preschool wheezing rhinovirus illnesses in children at risk to develop asthma. J Allergy Clin Immunol. 2011;128:532-8.e1-10 pubmed publisher
    ..Preschool rhinovirus (RV) wheezing illnesses predict an increased risk of childhood asthma; however, it is not clear how specific viral illnesses in early life relate to lung function later on in childhood...
  15. Kapoor A, Simmonds P, Dubovi E, Qaisar N, Henriquez J, Medina J, et al. Characterization of a canine homolog of human Aichivirus. J Virol. 2011;85:11520-5 pubmed publisher
    ..The discovery of CKoV provides new insights into the origin and evolution of AiV and the species specificity and pathogenesis of kobuviruses. ..
  16. Pham N, Takanashi S, Tran D, Trinh Q, Abeysekera C, Abeygunawardene A, et al. Human parechovirus infection in children hospitalized with acute gastroenteritis in Sri Lanka. J Clin Microbiol. 2011;49:364-6 pubmed publisher
    ..3%) were positive for human parechovirus (HPeV). Six different HPeV genotypes, including HPeV1, -3, -4, -5, -10, and -11, were identified, of these, HPeV11 was reported for the first time...
  17. McIntyre C, McWilliam Leitch E, Savolainen Kopra C, Hovi T, Simmonds P. Analysis of genetic diversity and sites of recombination in human rhinovirus species C. J Virol. 2010;84:10297-310 pubmed publisher
    ..The extensive sequence data from multiple genome regions of HRV-C and analyses of recombination in the current study will assist future formulation of consensus criteria for HRV-C type assignment and identification...
  18. Arden K, Chang A, Lambert S, Nissen M, Sloots T, Mackay I. Newly identified respiratory viruses in children with asthma exacerbation not requiring admission to hospital. J Med Virol. 2010;82:1458-61 pubmed publisher
    ..Larger, PCR-based studies are required to elucidate further the true impact of HRV species in childhood asthma exacerbations of both hospitalized and non-hospitalized cohorts...
  19. Wang C, Lan D, Hua X. Porcine kobuvirus from pig stool specimens in Shanghai, China. Virus Genes. 2011;43:350-2 pubmed publisher
    ..The phylogenetic analysis suggested the presence of multiple porcine kobuvirus lineages in Shanghai, China...
  20. Kolehmainen P, Oikarinen S, Koskiniemi M, Simell O, Ilonen J, Knip M, et al. Human parechoviruses are frequently detected in stool of healthy Finnish children. J Clin Virol. 2012;54:156-61 pubmed publisher
    ..Human parechoviruses (HPeVs) are common viruses mainly infecting young children. Most infections are mild, but HPeV3 causes severe CNS infections in new-born infants...
  21. Carmona Vicente N, Buesa J, Brown P, Merga J, Darby A, Stavisky J, et al. Phylogeny and prevalence of kobuviruses in dogs and cats in the UK. Vet Microbiol. 2013;164:246-52 pubmed publisher
    ..In addition, IgG antibody to AiV was also detected in cat sera, indicating for the first time that cats may also be susceptible to kobuvirus infection...
  22. Iikura K, Katsunuma T, Saika S, Saito S, Ichinohe S, Ida H, et al. Peripheral blood mononuclear cells from patients with bronchial asthma show impaired innate immune responses to rhinovirus in vitro. Int Arch Allergy Immunol. 2011;155 Suppl 1:27-33 pubmed publisher
    ..The present study aimed to elucidate the characteristics of the immune responses of asthmatic patients' peripheral blood mononuclear cells (PBMCs) to RV exposure...
  23. Nagarkar D, Bowman E, Schneider D, Wang Q, Shim J, Zhao Y, et al. Rhinovirus infection of allergen-sensitized and -challenged mice induces eotaxin release from functionally polarized macrophages. J Immunol. 2010;185:2525-35 pubmed publisher
    ..These data provide a new paradigm to explain RV-induced asthma exacerbations...
  24. Park S, Kim H, Moon H, Song D, Rho S, Han J, et al. Molecular detection of porcine kobuviruses in pigs in Korea and their association with diarrhea. Arch Virol. 2010;155:1803-11 pubmed publisher
  25. Smuts H, Workman L, Zar H. Human rhinovirus infection in young African children with acute wheezing. BMC Infect Dis. 2011;11:65 pubmed publisher
    ..The aim of this study was to determine the role of HRV as a cause of acute wheezing in South African children...
  26. An D, Jeoung H, Jeong W, Lee H, Park J, Kim B. Porcine kobuvirus from pig stool in Korea. Virus Genes. 2011;42:208-11 pubmed publisher
    ..Piglets under the age of 3 weeks were the main age group infected with porcine kobuvirus, which is the general case for other species of kobuviruses...
  27. Moreira L, Kamikawa J, Watanabe A, Carraro E, Leal E, Arruda E, et al. Frequency of human rhinovirus species in outpatient children with acute respiratory infections at primary care level in Brazil. Pediatr Infect Dis J. 2011;30:612-4 pubmed publisher
    ..HRV was detected in 27.5% of samples. HRV C was detected in 60.7% of wheezers, a frequency not different from that observed in nonwheezers (69.6%)...
  28. Zhong H, Lin Y, Sun J, Su L, Cao L, Yang Y, et al. Prevalence and genotypes of human parechovirus in stool samples from hospitalized children in Shanghai, China, 2008 and 2009. J Med Virol. 2011;83:1428-34 pubmed publisher
    ..This study provided useful data on the epidemiology of HPeV infection by documenting the distribution of genotypes, age of infection, and seasonal patterns in Shanghai, China...
  29. Dufkova L, Scigalkova I, Moutelikova R, Malenovska H, Prodělalová J. Genetic diversity of porcine sapoviruses, kobuviruses, and astroviruses in asymptomatic pigs: an emerging new sapovirus GIII genotype. Arch Virol. 2013;158:549-58 pubmed publisher
    ..The high prevalence rate of gastroenteritis-producing viruses in clinically healthy pigs represents a continuous source of infection of pigs, and possibly to humans...
  30. Slater L, Bartlett N, Haas J, Zhu J, Message S, Walton R, et al. Co-ordinated role of TLR3, RIG-I and MDA5 in the innate response to rhinovirus in bronchial epithelium. PLoS Pathog. 2010;6:e1001178 pubmed publisher
    ..Hence anti-viral defense within bronchial epithelium requires co-ordinated recognition of rhinovirus infection, initially via TLR3/TRIF and later via inducible RNA helicases...
  31. Pham N, Chan It W, Khamrin P, Nishimura S, Kikuta H, Sugita K, et al. Detection of human parechovirus in stool samples collected from children with acute gastroenteritis in Japan during 2007-2008. J Med Virol. 2011;83:331-6 pubmed publisher
    ..This is the first report of the circulation of HPeV, especially HPeV1 in Japan...
  32. Brand H, De Groot R, Galama J, Brouwer M, Teuwen K, Hermans P, et al. Infection with multiple viruses is not associated with increased disease severity in children with bronchiolitis. Pediatr Pulmonol. 2012;47:393-400 pubmed publisher
    ..This study evaluated the association between the detection of multiple viruses by RT-PCR and disease severity in children with bronchiolitis...
  33. Tapia G, Cinek O, Rasmussen T, Grinde B, Stene L, Rønningen K. Longitudinal study of parechovirus infection in infancy and risk of repeated positivity for multiple islet autoantibodies: the MIDIA study. Pediatr Diabetes. 2011;12:58-62 pubmed publisher
    ..The weak association of parechovirus present in the last 3 months before development of autoimmunity warrants further investigation...
  34. Stokes C, Ismail S, Dick E, Bennett J, Johnston S, Edwards M, et al. Role of interleukin-1 and MyD88-dependent signaling in rhinovirus infection. J Virol. 2011;85:7912-21 pubmed publisher
    ..Thus, IL-1? is a viable target for controlling the neutrophilia that is often found in inflammatory airway disease and is exacerbated by viral infection of the airways...
  35. Ito M, Yamashita T, Tsuzuki H, Kabashima Y, Hasegawa A, Nagaya S, et al. Detection of human parechoviruses from clinical stool samples in Aichi, Japan. J Clin Microbiol. 2010;48:2683-8 pubmed publisher
    ..A different pattern of clinical manifestations as well as seasonality suggested that there are different mechanisms of pathogenesis between HPeV-1 and HPeV-3 infections...
  36. Eis Hübinger A, Eckerle I, Helmer A, Reber U, Dresbach T, Buderus S, et al. Two cases of sepsis-like illness in infants caused by human parechovirus traced back to elder siblings with mild gastroenteritis and respiratory symptoms. J Clin Microbiol. 2013;51:715-8 pubmed publisher
    ..We report two unlinked cases of infant HPeV-3 sepsis-like illness whose sources could be traced back to elder siblings with mild gastroenteritis and respiratory symptoms...
  37. Korpi Steiner N, Valkenaar S, Bates M, Evans M, Gern J, Bertics P. Human monocytic cells direct the robust release of CXCL10 by bronchial epithelial cells during rhinovirus infection. Clin Exp Allergy. 2010;40:1203-13 pubmed publisher
    ..As HRV-induced cytokine levels in vivo are markedly elevated, this observation suggests that other mechanisms independent of direct viral infection may induce epithelial cell cytokine release...
  38. Bennett S, Harvala H, Witteveldt J, McWilliam Leitch E, McLeish N, Templeton K, et al. Rapid simultaneous detection of enterovirus and parechovirus RNAs in clinical samples by one-step real-time reverse transcription-PCR assay. J Clin Microbiol. 2011;49:2620-4 pubmed publisher
  39. Kuo C, Lim S, King N, Johnston S, Burgess J, Black J, et al. Rhinovirus infection induces extracellular matrix protein deposition in asthmatic and nonasthmatic airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol. 2011;300:L951-7 pubmed publisher
    ..Our results suggest that viruses may contribute to airway remodeling through increased ECM deposition, which in turn may contribute to increased ASM mass via increased cell migration...
  40. Han T, Kim C, Park S, Chung J, Hwang E. Detection of human parechoviruses in children with gastroenteritis in South Korea. Arch Virol. 2011;156:1471-5 pubmed publisher
    ..Two HPeV-4 strains showed discordant phylogenic relationships in the 3D gene, suggesting that recombination had occurred. This is the first study reporting the detection of HPeVs in children with GE in Korea...
  41. Ghazi F, Ataei Z, Dabirmanesh B. Molecular detection of human parechovirus type 1 in stool samples from children with diarrhea. Int J Infect Dis. 2012;16:e673-6 pubmed publisher
    ..Since there is no accurate information about the incidence and epidemiology of HPeV-1 in Iran, this study was designed to describe the frequency of HPeV-1 in stool samples from children under 4 years of age with gastroenteritis...
  42. Lee M, Jeoung H, Lim J, Song J, Song D, An D. Kobuvirus in South Korean black goats. Virus Genes. 2012;45:186-9 pubmed publisher
    ..The similarity of the sequence of the 08KG680 strains with the bovine kobuvirus indicate that the infectious may have originated from cattle, but the possible source for remaining strains could not be classified...
  43. Jackson D, Johnston S. The role of viruses in acute exacerbations of asthma. J Allergy Clin Immunol. 2010;125:1178-87; quiz 1188-9 pubmed publisher
  44. Lukashev A. Recombination among picornaviruses. Rev Med Virol. 2010;20:327-37 pubmed publisher
    ..This review covers existing evidence of recombination in most genera of the family Picornaviridae and possible implications for diagnostics, epidemiology and classification...
  45. Nascimento M, Souza A, Ferreira A, Rodrigues J, Abramovici S, Silva Filho L. High rate of viral identification and coinfections in infants with acute bronchiolitis. Clinics (Sao Paulo). 2010;65:1133-7 pubmed
    ..To determine the viruses and risk factors associated with hospital and intensive care unit (ICU) admissions in infants with acute bronchiolitis...
  46. Onyango C, Welch S, Munywoki P, Agoti C, Bett A, Ngama M, et al. Molecular epidemiology of human rhinovirus infections in Kilifi, coastal Kenya. J Med Virol. 2012;84:823-31 pubmed publisher
  47. Laza Stanca V, Message S, Edwards M, Parker H, Zdrenghea M, Kebadze T, et al. The role of IL-15 deficiency in the pathogenesis of virus-induced asthma exacerbations. PLoS Pathog. 2011;7:e1002114 pubmed publisher
    ..Deficient IL-15 production in asthma may be important in the pathogenesis of asthma exacerbations...
  48. Iwane M, Prill M, Lu X, Miller E, Edwards K, Hall C, et al. Human rhinovirus species associated with hospitalizations for acute respiratory illness in young US children. J Infect Dis. 2011;204:1702-10 pubmed publisher
    ..HRV-A and HRV-C were associated with ARI hospitalization and serious illness outcomes. ..
  49. Chattoraj S, Ganesan S, Faris A, Comstock A, Lee W, Sajjan U. Pseudomonas aeruginosa suppresses interferon response to rhinovirus infection in cystic fibrosis but not in normal bronchial epithelial cells. Infect Immun. 2011;79:4131-45 pubmed publisher
    ..Further, increased oxidative stress in CF cells appears to modulate the innate immune responses to coinfection...
  50. Okitsu S, Khamrin P, Thongprachum A, Hidaka S, Kongkaew S, Kongkaew A, et al. Sequence analysis of porcine kobuvirus VP1 region detected in pigs in Japan and Thailand. Virus Genes. 2012;44:253-7 pubmed publisher
    ..Since this strain was previously found to be closely related to bovine kobuviruses in the 3D gene region, it may be a natural recombinant...
  51. Reuter G, Boros A, Pankovics P. Kobuviruses - a comprehensive review. Rev Med Virol. 2011;21:32-41 pubmed publisher
  52. Tapparel C, Siegrist F, Petty T, Kaiser L. Picornavirus and enterovirus diversity with associated human diseases. Infect Genet Evol. 2013;14:282-93 pubmed publisher
    ..Better characterization of these ubiquitous human pathogens may help to develop vaccines or antiviral treatments and to monitor the emergence of new strains...
  53. Chattoraj S, Ganesan S, Jones A, Helm J, Comstock A, Bright Thomas R, et al. Rhinovirus infection liberates planktonic bacteria from biofilm and increases chemokine responses in cystic fibrosis airway epithelial cells. Thorax. 2011;66:333-9 pubmed publisher
    ..These observations imply that acute RV infection may increase lower respiratory symptoms by increasing planktonic bacterial load. However, the underlying mechanisms are not known...