coronaviridae infections


Summary: Virus diseases caused by CORONAVIRIDAE.

Top Publications

  1. Vijaykrishna D, Smith G, Zhang J, Peiris J, Chen H, Guan Y. Evolutionary insights into the ecology of coronaviruses. J Virol. 2007;81:4012-20 pubmed
    ..Further surveillance of bat and other animal populations is needed to fully describe the ecology and evolution of this virus family...
  2. Falcón A, Vazquez Moron S, Casas I, Aznar C, Ruiz G, Pozo F, et al. Detection of alpha and betacoronaviruses in multiple Iberian bat species. Arch Virol. 2011;156:1883-90 pubmed publisher
    ..Interestingly, although some of these viruses are related to other European BatCoV, or to Asian CoV, some of the viruses found in Spain cluster in new groups of ? and ? CoV...
  3. Woo P, Lau S, Lam C, Lau C, Tsang A, Lau J, et al. Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacor. J Virol. 2012;86:3995-4008 pubmed publisher
  4. Alexander D, Gough R. Isolation of avian infectious bronchitis virus from experimentally infected chickens. Res Vet Sci. 1977;23:344-7 pubmed
  5. Almazán F, DeDiego M, Sola I, Zúñiga S, Nieto Torres J, Marquez Jurado S, et al. Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate. MBio. 2013;4:e00650-13 pubmed publisher
    ..This virus constitutes a vaccine candidate that may represent a balance between safety and efficacy for the induction of mucosal immunity, which is needed to prevent MERS-CoV infection. ..
  6. Machii K, Iwai H, Otsuka Y, Ueda K, Hirano N. Reactivities of 4 murine coronavirus antigens with immunized or naturally infected rat sera by enzyme linked immunosorbent assay. Jikken Dobutsu. 1988;37:251-5 pubmed
    ..These results suggested that, although homologous antigens are best to detect SDAV or PCV infection by ELISA, MHV antigen can be used if highly cross-reactive viral strain is selected. ..
  7. Miyazaki T, Okamoto H, Kageyama T, Kobayashi T. Viremia-associated ana-aki-byo, a new viral disease in color carp Cyprinus carpio in Japan. Dis Aquat Organ. 2000;39:183-92 pubmed
    ..Carp experimentally inoculated with the cultured virus showed virus transmission, and the same pathological signs of the disease and mortalities as in natural infections. ..
  8. Mao J, Zhao Y, She R, Xiao P, Tian J, Chen J. One case of swine hepatitis E virus and porcine reproductive and respiratory syndrome virus co-infection in weaned pigs. Virol J. 2013;10:341 pubmed publisher
    ..We speculated that co-infection with PRRSV and HEV might lead to more serious problems. ..
  9. Lu C, Yao H, Eichhorn W. Coronavirus as an agent of neonatal calf diarrhea in a Chinese dairy cattle farm. Zentralbl Veterinarmed B. 1991;38:473-6 pubmed
    ..In the last years we have developed diagnostic methods including a monoclonal antibody-based ELISA to detect BCV and other diarrheal viruses. In this study, the diagnosis of an outbreak of BCV in chinese dairy cattle is described. ..

More Information

Publications108 found, 100 shown here

  1. Ohnuma K, Haagmans B, Hatano R, Raj V, Mou H, Iwata S, et al. Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibody. J Virol. 2013;87:13892-9 pubmed publisher
    ..These findings indicate that both 2F9 and YS110 are potential therapeutic agents for MERS-CoV infection. YS110, in particular, is a good candidate for immediate testing as a therapeutic modality for MERS. ..
  2. Vannier P. Disorders induced by the experimental infection of pigs with the porcine respiratory coronavirus (P.R.C.V.). Zentralbl Veterinarmed B. 1990;37:177-80 pubmed
    ..The reasons for the variability of effects of experimental infection observed in previous trials, are discussed. ..
  3. Jung K, Ahn K, Chae C. Decreased activity of brush border membrane-bound digestive enzymes in small intestines from pigs experimentally infected with porcine epidemic diarrhea virus. Res Vet Sci. 2006;81:310-5 pubmed
    ..Reduced enzymatic activity and villous atrophy in the small intestine is thought to result in a maldigestive and malabsorptive diarrhea. ..
  4. Mair T, Taylor F, Harbour D, Pearson G. Concurrent cryptosporidium and coronavirus infections in an Arabian foal with combined immunodeficiency syndrome. Vet Rec. 1990;126:127-30 pubmed
    ..Intestinal infection by coronavirus (not previously recorded in cases of the syndrome) and cryptosporidia was identified. Histopathological evidence also suggested the presence of an adenovirus infection. ..
  5. Barthold S, de Souza M, Smith A. Susceptibility of laboratory mice to intranasal and contact infection with coronaviruses of other species. Lab Anim Sci. 1990;40:481-5 pubmed
    ..This study demonstrates that although these coronaviruses are antigenically closely related, they are biologically different viruses and disease patterns in susceptible infant mice can be used to differentiate viruses. ..
  6. Boschert K, Schoeb T, Chandler D, Dillehay D. Inhibition of phagocytosis and interleukin-1 production in pulmonary macrophages from rats with sialodacryoadenitis virus infection. J Leukoc Biol. 1988;44:87-92 pubmed
    ..Effects of SDAV infection on lung macrophages could increase host susceptibility to other pathogens or complicate studies of respiratory tract immunity. ..
  7. Halbur P, Paul P, Vaughn E, Andrews J. Experimental reproduction of pneumonia in gnotobiotic pigs with porcine respiratory coronavirus isolate AR310. J Vet Diagn Invest. 1993;5:184-8 pubmed
    ..PRCV was not isolated from the lungs or intestines of control pigs. PRCV was also isolated from the nasal and rectal swabs of inoculated but not of control pigs. ..
  8. Monroe S, Glass R, Noah N, Flewett T, Caul E, Ashton C, et al. Electron microscopic reporting of gastrointestinal viruses in the United Kingdom, 1985-1987. J Med Virol. 1991;33:193-8 pubmed
    ..We have attempted to identify the reasons for this. We make suggestions for improving the detection of human fecal viruses, and we recognize the need for continued surveillance of these agents...
  9. Ohno S, Steer B, Sattler C, Adler H. ORF23 of murine gammaherpesvirus 68 is non-essential for in vitro and in vivo infection. J Gen Virol. 2012;93:1076-80 pubmed publisher
    ..A phenotype of the ORF23 deletion mutant, reflected by a moderate reduction in lytic replication and latency amplification, was only detectable in the face of direct competition to the parental virus...
  10. Fazzini E, Fleming J, Fahn S. Cerebrospinal fluid antibodies to coronavirus in patients with Parkinson's disease. Mov Disord. 1992;7:153-8 pubmed
    ..05). Responses (p greater than 0.05) to A (0.1722 vs. 0.0929) and O (0.0839 vs. 0.0446) were greater than that to E (0.1261 vs. 0.0946). These results suggest that there may be an association between coronavirus and PD. ..
  11. Kemp D, Percy D, Hayes M. Lack of effects of viral sialoadenitis and depletion of epidermal growth factor on initiation of hepatic carcinogenesis in the rat. Toxicol Pathol. 1991;19:156-63 pubmed
    ..Based on this model, concurrent infection with SDAV does not appear to have any significant effects on the initial stages of chemical hepatocarcinogenesis in the rat. ..
  12. Evermann J, Heeney J, McKeirnan A, O Brien S. Comparative features of a coronavirus isolated from a cheetah with feline infectious peritonitis. Virus Res. 1989;13:15-27 pubmed
  13. Percy D, Hayes M, Kocal T, Wojcinski Z. Depletion of salivary gland epidermal growth factor by sialodacryoadenitis virus infection in the Wistar rat. Vet Pathol. 1988;25:183-92 pubmed
    ..These studies suggest that a clinical (or subclinical) infection with SDA virus could have significant effects on experimental studies on EGF-dependent functions, including reproductive physiology and carcinogenesis. ..
  14. De Herdt P, Ducatelle A, Uyttebroek A, Sneep A, Torbeyns R. Infectious bronchitis serology in broilers and broiler breeders: correlations between antibody titers and performance in vaccinated flocks. Avian Dis. 2001;45:612-9 pubmed
    ..We concluded that IBV vaccination strategies should aim at high and uniform antibody titers in the broiler breeders. ..
  15. Kadoi K, Sugioka H, Satoh T, Kadoi B. The propagation of a porcine epidemic diarrhea virus in swine cell lines. New Microbiol. 2002;25:285-90 pubmed
    ..Small but clear plaques were formed under an agar overlay medium on the cells. The infective titer in the order of 10(7.00-7.50) TCID50 per ml was obtained at usual incubation temperature. ..
  16. Karaca K, Naqi S, Palukaitis P, Lucio B. Serological and molecular characterization of three enteric isolates of infectious bronchitis virus of chickens. Avian Dis. 1990;34:899-904 pubmed
    ..This and the co-fingerprinting data suggested that the three field isolates may have emerged from the Connecticut virus through mutation(s). The mutation(s) apparently involved the S1 protein gene that determines the virus serotype. ..
  17. Christianson K, Ingersoll J, Landon R, Pfeiffer N, Gerber J. Characterization of a temperature sensitive feline infectious peritonitis coronavirus. Arch Virol. 1989;109:185-96 pubmed
    ..These unique characteristics possessed by TS-FIPV may account for its nonvirulent nature and ability to stimulate protective immune responses in cats. ..
  18. Perlman S, Schelper R, Ries D. Maternal antibody-modulated MHV-JHM infection in C57BL/6 and BALB/c mice. Adv Exp Med Biol. 1987;218:297-305 pubmed
    ..5. This model should be useful for the study of the viral and immune factors important in MHV-induced viral demyelination. ..
  19. Stoddart C, Barlough J, Baldwin C, Scott F. Attempted immunisation of cats against feline infectious peritonitis using canine coronavirus. Res Vet Sci. 1988;45:383-8 pubmed
    ..The five surviving cats developed FIP after subsequent challenge with a fivefold higher dose of FIPV. Thus heterotypic vaccination of cats with CCV did not provide effective protection against FIPV challenge. ..
  20. Kuljić Kapulica N, Budisin A. [Coronaviruses]. Srp Arh Celok Lek. 1992;120:215-8 pubmed
    ..However, in the last years more attention has been paid to the role of human corona viruses in the provocation of sickness in man and they are becoming a special field of interest in scientific studies. ..
  21. Martins N, Mockett A, Cook J. A method for the rapid purification of serum IgM for the diagnosis of recent viral infections of chickens. J Virol Methods. 1990;29:117-25 pubmed
  22. Otsuki K, Nakamura T, Kawaoka Y, Tsubokura M. Interferon induction by several strains of avian infectious bronchitis virus, a coronavirus, in chickens. Acta Virol. 1988;32:55-9 pubmed
    ..All strains induced interferon (IFN) in several organs of six-week-old SPF chickens. However, the extent of IFN formation in these chickens was not necessarily the same from one strain to another. ..
  23. Walsh K, Lodoen M, Edwards R, Lanier L, Lane T. Evidence for differential roles for NKG2D receptor signaling in innate host defense against coronavirus-induced neurological and liver disease. J Virol. 2008;82:3021-30 pubmed
  24. Wang L, Byrum B, Zhang Y. Porcine coronavirus HKU15 detected in 9 US states, 2014. Emerg Infect Dis. 2014;20:1594-5 pubmed publisher
  25. Sedgwick J, Schwender S, Imrich H, Dörries R, Butcher G, ter Meulen V. Isolation and direct characterization of resident microglial cells from the normal and inflamed central nervous system. Proc Natl Acad Sci U S A. 1991;88:7438-42 pubmed
    ..In normal CNS, a very small population of blood-derived CD45high-expressing cells are present; most MHC class II expression is associated with these few cells and not with the resident microglia. ..
  26. Van Kruiningen H, Castellano V, Torres A, Sharpee R. Serologic evidence of coronavirus infection in New York and New England dairy cattle with winter dysentery. J Vet Diagn Invest. 1991;3:293-6 pubmed
    ..Adult cattle in all 8 herds seroconverted. These findings complement previously reported immunoperoxidase and electron microscopic evidence, suggesting an etiologic role for an enteric coronavirus in this disease. ..
  27. Butcher G, Winterfield R, Shapiro D. An outbreak of nephropathogenic H13 infectious bronchitis in commercial broilers. Avian Dis. 1989;33:823-6 pubmed
    ..Tracheal changes included marked thickening of the mucosa, desquamation of ciliated and glandular epithelia and replacement with a stratified undifferentiated epithelium, and inflammatory cell infiltration. ..
  28. Collins A, Sorensen O. Regulation of viral persistence in human glioblastoma and rhabdomyosarcoma cells infected with coronavirus OC43. Microb Pathog. 1986;1:573-82 pubmed
    ..The relative ease of establishment and cure of these persistent infectious makes them attractive as models to study coronavirus regulatory processes. ..
  29. Song D, Kang B, Lee S, Yang J, Moon H, Oh J, et al. Use of an internal control in a quantitative RT-PCR assay for quantitation of porcine epidemic diarrhea virus shedding in pigs. J Virol Methods. 2006;133:27-33 pubmed
    ..This suggests that measurement of PEDV shedding viral load in pigs, by quantitative RT-PCR, may be a useful tool for estimating the transmission potential of PEDV in the swine population. ..
  30. Woods R, Wesley R. Seroconversion of pigs in contact with dogs exposed to canine coronavirus. Can J Vet Res. 1992;56:78-80 pubmed
    ..The dogs shed CCV for eight days after exposure. All three pigs developed neutralizing antibodies against CCV and transmissible gastroenteritis virus by 14 days after they were exposed to the dogs. ..
  31. Heckert R, Saif L, Myers G. Mucosal and systemic isotype-specific antibody responses to bovine coronavirus structural proteins in naturally infected dairy calves. Am J Vet Res. 1991;52:852-7 pubmed
    ..However, calves with BCV respiratory tract or enteric tract infections had no detectable passive antibodies to any BCV proteins in nasal secretions or feces. ..
  32. Mertsola J, Ziegler T, Ruuskanen O, Vanto T, Koivikko A, Halonen P. Recurrent wheezy bronchitis and viral respiratory infections. Arch Dis Child. 1991;66:124-9 pubmed
    ..The incidence of wheezing was not associated with IgE mediated atopy, with positive virological tests, or with fever during virus infection, but was associated with parental smoking and more than one sibling. ..
  33. Woo P, Lau S, Lam C, Tsang A, Hui S, Fan R, et al. Discovery of a novel bottlenose dolphin coronavirus reveals a distinct species of marine mammal coronavirus in Gammacoronavirus. J Virol. 2014;88:1318-31 pubmed publisher
    ..We propose a distinct species, Cetacean coronavirus, in Gammacoronavirus, to include BdCoV HKU22 and BWCoV SW1, whereas IBV and its closely related bird CoVs represent another species, Avian coronavirus, in Gammacoronavirus. ..
  34. Bumstead N, Huggins M, Cook J. Genetic differences in susceptibility to a mixture of avian infectious bronchitis virus and Escherichia coli. Br Poult Sci. 1989;30:39-48 pubmed
    ..5. The pattern of mortality in F2 and backcross progeny of matings was compatible with the inheritance of a dominant autosomal resistance gene and showed no evidence of association with the major histocompatibility complex. ..
  35. Perlman S, Ries D. The astrocyte is a target cell in mice persistently infected with mouse hepatitis virus, strain JHM. Microb Pathog. 1987;3:309-14 pubmed
    ..These results indicate that astrocytes are a target cell in both symptomatic and asymptomatic mice persistently infected with MHV-JHM, and suggest that the astrocyte is a potential cellular reservoir for MHV-JHM in asymptomatic mice. ..
  36. Garner M, Ramsell K, Morera N, Juan Sallés C, Jimenez J, Ardiaca M, et al. Clinicopathologic features of a systemic coronavirus-associated disease resembling feline infectious peritonitis in the domestic ferret (Mustela putorius). Vet Pathol. 2008;45:236-46 pubmed publisher
    ..Partial sequencing of the coronavirus spike gene obtained from frozen tissue indicates that the virus is related to ferret enteric coronavirus. ..
  37. Fiscus S, Rivoire B, Teramoto Y. Humoral immune response of cats to virulent and avirulent feline infectious peritonitis virus isolates. Adv Exp Med Biol. 1987;218:559-68 pubmed
    ..However, all cats except uninoculated controls developed neutralizing titers to FIPV-UCD-2. Competition ELISAs were used to analyze the specific humoral immune responses of cats to structural polypeptides of the viruses. ..
  38. Rao G, Haseman J, Edmondson J. Influence of viral infections on body weight, survival, and tumor prevalence in Fischer 344/NCr rats on two-year studies. Lab Anim Sci. 1989;39:389-93 pubmed
    ..However, none of the tumor prevalence and survival differences were statistically significant when interlaboratory variability and time-related effects were taken into account. ..
  39. Cross A, McCarron R, McFarlin D, Raine C. Adoptively transferred acute and chronic relapsing autoimmune encephalomyelitis in the PL/J mouse and observations on altered pathology by intercurrent virus infection. Lab Invest. 1987;57:499-512 pubmed
    ..The pathology of autoimmune mediated demyelination may be altered in the presence of coronavirus infection but the clinical pattern of EAE expression did not differ between virus-free and coronavirus-infected mice. ..
  40. Kiss I, Ros C, Kecskemeti S, Tanyi J, Klingeborn S, Belak S. Observations on the quasispecies composition of three animal pathogenic RNA viruses. Acta Vet Hung. 1999;47:471-80 pubmed
  41. Penzes Z, Meszaros J. Comparison of different computational methods for measuring antibodies to avian infectious bronchitis virus in single serum dilution. Acta Vet Hung. 1992;40:311-21 pubmed
    ..Titres obtained by the different methods showed a good correlation for sera of low, medium and high antibody levels. The authors recommend the use of the single dilution method...
  42. Gaertner D, Winograd D, Compton S, Paturzo F, Smith A. Development and optimization of plaque assays for rat coronaviruses. J Virol Methods. 1993;43:53-64 pubmed
    ..These methods will facilitate production of cloned virus stocks for study of RCV biology and virus quantification for in vitro and in vivo studies of RCVs...
  43. Sasaki I, Kazusa Y, Shirai J, Taniguchi T, Honda E. Neutralizing test of hemagglutinating encephalomyelitis virus (HEV) in FS-L3 cells cultured without serum. J Vet Med Sci. 2003;65:381-3 pubmed
    ..Our results support the idea that the VN is a more reliable measure of HEV infection than the conventionally used HI test...
  44. Kennedy M, Citino S, Dolorico T, McNabb A, Moffat A, Kania S. Detection of feline coronavirus infection in captive cheetahs (Acinonyx jubatus) by polymerase chain reaction. J Zoo Wildl Med. 2001;32:25-30 pubmed
    ..Screening programs in cheetah populations for feline coronavirus infection may be most reliable if a combination of serologic analysis and viral detection by polymerase chain reaction is used...
  45. Garcelon D, Wayne R, Gonzales B. A serologic survey of the island fox (Urocyon littoralis) on the Channel Islands, California. J Wildl Dis. 1992;28:223-9 pubmed
    ..Antibody prevalence of canine herpesvirus, canine coronavirus, leptospirosis and toxoplasmosis were low. Antibodies against canine distemper virus were not detected...
  46. Abraham G, Roeder P, Zewdu R. Agents associated with neonatal diarrhoea in Ethiopian dairy calves. Trop Anim Health Prod. 1992;24:74-80 pubmed
    ..It is concluded that BEC is the major infectious cause of neonatal calf diarrhoea in the Ethiopian dairy herds studied with RV and K99 ETEC also contributing to morbidity, either alone or as mixed infections...
  47. Brown I, Paton D. Serological studies of transmissible gastroenteritis in Great Britain, using a competitive ELISA. Vet Rec. 1991;128:500-3 pubmed
    ..All British isolates of TGEV tested by the indirect fluorescent antibody test were recognised by the monoclonal antibody 1D.B12, the indicator antibody in the ELISA...
  48. Dea S, Verbeek A, Tijssen P. Transmissible enteritis of turkeys: experimental inoculation studies with tissue-culture-adapted turkey and bovine coronaviruses. Avian Dis. 1991;35:767-77 pubmed
  49. Percy D, Bond S, Paturzo F, Bhatt P. Duration of protection from reinfection following exposure to sialodacryoadenitis virus in Wistar rats. Lab Anim Sci. 1990;40:144-9 pubmed
    ..The results indicate that reinfection with homologous rat coronavirus can occur as early as 6 months after the initial infection, and such rats can transmit the infection to contact controls...
  50. Wege H, Winter J, Meyermann R. The peplomer protein E2 of coronavirus JHM as a determinant of neurovirulence: definition of critical epitopes by variant analysis. J Gen Virol. 1988;69 ( Pt 1):87-98 pubmed
    ..These variants caused acute hepatitis and encephalomyelitis in mice. In contrast, JHM variants with changes in site E2-Ba had a strong propensity to induce chronic disease accompanied by demyelination persisting for several months...
  51. Zimmer M, Dales S. In vivo and in vitro models of demyelinating diseases. XXIV. The infectious process in cyclosporin A treated Wistar Lewis rats inoculated with JHM virus. Microb Pathog. 1989;6:7-16 pubmed
    ..When cellular immunity is suppressed or absent the disease process is altered from one in which white matter demyelination predominates to another form of disease in which neuronal involvement is prominent...
  52. Mcvey D, Rudd R, Toshach K, Moore W, Keeton K. Systemic autoimmune disease and concurrent nematode infection in a dog. J Am Vet Med Assoc. 1989;195:957-60 pubmed
    ..Serotest data generated from the dog's serum obtained at the time of referral suggested that autoantibodies and circulating immune complexes may have included IgE isotypes...
  53. Mullaney T, Newman L, Whitehair C. Humoral immune response of the bovine fetus to in utero vaccination with attenuated bovine coronavirus. Am J Vet Res. 1988;49:156-9 pubmed
    ..Although in utero vaccination with a coronavirus vaccine stimulated immunity in the newborn calf, the frequency of abortions (2 of 14 cows inoculated intra-amniotically) and premature births (4 of 14) precluded practical application...
  54. Stoddart M, Gaskell R, Harbour D, Gaskell C. Virus shedding and immune responses in cats inoculated with cell culture-adapted feline infectious peritonitis virus. Vet Microbiol. 1988;16:145-58 pubmed
    ..Antibody titres, measured by immunofluorescence and by virus neutralization, rose rapidly to very high levels in all cats, regardless of the route of inoculation...
  55. Wilson G, Dales S. In vivo and in vitro models of demyelinating disease: efficiency of virus spread and formation of infectious centers among glial cells is genetically determined by the murine host. J Virol. 1988;62:3371-7 pubmed
    ..Since cells from (SJL x CD.1)F1 mice were fully susceptible to JHMV, resistance to virus spread must be due to a deficiency in some factor, perhaps a proteolytic activity necessary for dissemination...
  56. Ellis J, McLean N, Hupaelo R, Haines D. Detection of coronavirus in cases of tracheobronchitis in dogs: a retrospective study from 1971 to 2003. Can Vet J. 2005;46:447-8 pubmed
  57. Addie D, Jarrett O. A study of naturally occurring feline coronavirus infections in kittens. Vet Rec. 1992;130:133-7 pubmed
    ..In this survey, cases of feline infectious peritonitis occurred in kittens from households where the initial presentation had been enteritis and vice versa. Therefore no difference in epidemiology could be found...
  58. Murray R, Cai G, Hoel K, Zhang J, Soike K, Cabirac G. Coronavirus infects and causes demyelination in primate central nervous system. Virology. 1992;188:274-84 pubmed
    ..This study suggests that human CNS may be susceptible to coronavirus infection...
  59. Schultze B, Herrler G. Bovine coronavirus uses N-acetyl-9-O-acetylneuraminic acid as a receptor determinant to initiate the infection of cultured cells. J Gen Virol. 1992;73 ( Pt 4):901-6 pubmed
  60. Saif L, Brock K, Redman D, Kohler E. Winter dysentery in dairy herds: electron microscopic and serological evidence for an association with coronavirus infection. Vet Rec. 1991;128:447-9 pubmed
    ..These findings provide additional evidence for a possible role for bovine coronavirus in the aetiology of winter dysentery. Furthermore, this is the first report of a group B rotavirus associated with diarrhoea in adult cattle...
  61. van Nieuwstadt A, Zetstra T. Use of two enzyme-linked immunosorbent assays to monitor antibody responses in swine with experimentally induced infection with porcine epidemic diarrhea virus. Am J Vet Res. 1991;52:1044-50 pubmed
    ..The latter technique is easier to perform and discriminates well between infected and noninfected pigs, which makes this test useful for routine diagnosis and serologic surveys of porcine epidemic diarrhea...
  62. Alenius S, Niskanen R, Juntti N, Larsson B. Bovine coronavirus as the causative agent of winter dysentery: serological evidence. Acta Vet Scand. 1991;32:163-70 pubmed
    ..In conclusion, BCV is commonly detected in animals suffering from winter dysentery. A co-infection with BVDV appears to aggravate the disease...
  63. Cox E, Pensaert M, Hooyberghs J, Van Deun K. Sites of replication of a porcine respiratory coronavirus in 5-week-old pigs with or without maternal antibodies. Adv Exp Med Biol. 1990;276:429-33 pubmed
    ..Upon inoculation of 10(5) or 10(7) TCID50 directly into the lumen of the cranial jejunum, no intestinal replication could be demonstrated...
  64. Butcher G, Gelb J, Collisson E. Comparisons of the genomic RNA of Arkansas DPI embryonic passages 10 and 100, Australian T, and Massachusetts 41 strains of infectious bronchitis virus. Avian Dis. 1990;34:253-9 pubmed
    ..Fingerprinting is reliable and sensitive, and should be used in combination with other characterization methods for identifying and differentiating IBV strains...
  65. Hok K. Demonstration of feline corona virus (FCV) antigen in organs of cats suspected of feline infectious peritonitis (FIP) disease. APMIS. 1990;98:659-64 pubmed
    ..001). A similar distribution of the incidence of FCV antigen in the investigated organs was observed in these two groups...
  66. Chandra M. Comparative nephropathogenicity of different strains of infectious bronchitis virus in chickens. Poult Sci. 1987;66:954-9 pubmed
    ..The Australian T strain induced the most rapid and the most severe kidney lesions followed by Holte, Gray, and M 41 in descending order...
  67. Afzelius B. Ultrastructure of human nasal epithelium during an episode of coronavirus infection. Virchows Arch. 1994;424:295-300 pubmed
    ..The ciliated cells seem not to be destroyed by the viruses, although in many cases the cilia are withdrawn into the cell body. The loss of cilia is likely to cause rhinorrhoea...
  68. Tennant B, Gaskell R, Jones R, Gaskell C. Studies on the epizootiology of canine coronavirus. Vet Rec. 1993;132:7-11 pubmed
    ..It would appear that although canine coronavirus is widespread, the role of the virus in canine enteritis is still equivocal...
  69. Pijpers A, van Nieuwstadt A, Terpstra C, Verheijden J. Porcine epidemic diarrhoea virus as a cause of persistent diarrhoea in a herd of breeding and finishing pigs. Vet Rec. 1993;132:129-31 pubmed
    ..The infections and diarrhoea persisted in six- to 10-week-old pigs in separate barns. The suckling pigs and young weaners appeared to be spared from the infections...
  70. Decimo D, Boespflug O, Meunier Rotival M, Hadchouel M, Tardieu M. Genetic restriction of murine hepatitis virus type 3 expression in liver and brain: comparative study in BALB/c and C3H mice by immunochemistry and hybridization in situ. Arch Virol. 1993;130:269-77 pubmed
  71. Kuo L, Masters P. Functional analysis of the murine coronavirus genomic RNA packaging signal. J Virol. 2013;87:5182-92 pubmed publisher
    ..However, the PS was found to provide a distinct selective advantage to MHV. Viruses containing the PS readily outcompeted their otherwise isogenic counterparts lacking the PS...
  72. Tennant B, Gaskell R, Kelly D, Carter S, Gaskell C. Canine coronavirus infection in the dog following oronasal inoculation. Res Vet Sci. 1991;51:11-8 pubmed
    ..Specific anti-CCV IgM was first detected in plasma three days after inoculation and IgG on days 4 to 7. Small amounts of anti-CCV IgG, IgM and IgA were detected in duodenal secretion, but none in bile...
  73. Rao G. Light intensity-associated eye lesions of Fischer 344 rats in long-term studies. Toxicol Pathol. 1991;19:148-55 pubmed
  74. Vennema H, de Groot R, Harbour D, Dalderup M, Gruffydd Jones T, Horzinek M, et al. Immunogenicity of recombinant feline infectious peritonitis virus spike protein in mice and kittens. Adv Exp Med Biol. 1990;276:217-22 pubmed
    ..When kittens were immunized with the recombinant, low titers of neutralizing antibodies were obtained. After challenge with FIPV, these animals succumbed earlier than the vWR-immunized control group ("early death syndrome")...
  75. Robbins S, Hamel C, Detrick B, Hooks J. Murine coronavirus induces an acute and long-lasting disease of the retina. Lab Invest. 1990;62:417-26 pubmed
    ..This murine disease may be considered a model for degenerative diseases of the pigment epithelium and photoreceptors in man...
  76. Watanabe R, Wege H, ter Meulen V. Comparative analysis of coronavirus JHM-induced demyelinating encephalomyelitis in Lewis and Brown Norway rats. Lab Invest. 1987;57:375-84 pubmed
    ..These observations demonstrate the pathogenetic importance of host factors in the development of virus-induced demyelination...
  77. Fleming J, Shubin R, Sussman M, Casteel N, Stohlman S. Monoclonal antibodies to the matrix (E1) glycoprotein of mouse hepatitis virus protect mice from encephalitis. Virology. 1989;168:162-7 pubmed
    ..These results demonstrate that antibodies which are specific for a viral matrix protein are able to alter the course of disease...
  78. Percy D, Wojcinski Z, Schunk M. Sequential changes in the harderian and exorbital lacrimal glands in Wistar rats infected with sialodacryoadenitis virus. Vet Pathol. 1989;26:238-45 pubmed
    ..Persistent lesions also indicate that normal functions of these glands may be compromised for up to several weeks following outbreaks of SDA...
  79. Sorensen O, Dugre R, Percy D, Dales S. In vivo and in vitro models of demyelinating disease: endogenous factors influencing demyelinating disease caused by mouse hepatitis virus in rats and mice. Infect Immun. 1982;37:1248-60 pubmed
  80. Andrews S, Westbury B, Francis M. In vitro compatibility of an anticoccidial vaccine with live infectious bronchitis and live Newcastle disease vaccines. Vet Rec. 2003;152:717-8 pubmed
  81. Lima F, Campos F, Kunert Filho H, Batista H, Carnielli P, Cibulski S, et al. Detection of Alphacoronavirus in velvety free-tailed bats (Molossus molossus) and Brazilian free-tailed bats (Tadarida brasiliensis) from urban area of Southern Brazil. Virus Genes. 2013;47:164-7 pubmed publisher
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