mumps

Summary

Summary: An acute infectious disease caused by RUBULAVIRUS, spread by direct contact, airborne droplet nuclei, fomites contaminated by infectious saliva, and perhaps urine, and usually seen in children under the age of 15, although adults may also be affected. (From Dorland, 28th ed)

Top Publications

  1. Santak M, Lang Balija M, Ivancic Jelecki J, Kosutic Gulija T, Ljubin Sternak S, Forcic D. Antigenic differences between vaccine and circulating wild-type mumps viruses decreases neutralization capacity of vaccine-induced antibodies. Epidemiol Infect. 2013;141:1298-309 pubmed publisher
    A recent resurgence of mumps in doubly vaccinated cohorts has been observed, identifying genotype G as the current predominant genotype...
  2. Dayan G, Rubin S. Mumps outbreaks in vaccinated populations: are available mumps vaccines effective enough to prevent outbreaks?. Clin Infect Dis. 2008;47:1458-67 pubmed publisher
    Increased reports of mumps in vaccinated populations prompted a review of the performance of mumps vaccines. The effectiveness of prior vaccination with 1 dose of vaccine ranged from 72.8% to 91% for the Jeryl Lynn strain, from 54...
  3. Yoshida N, Fujino M, Miyata A, Nagai T, Kamada M, Sakiyama H, et al. Mumps virus reinfection is not a rare event confirmed by reverse transcription loop-mediated isothermal amplification. J Med Virol. 2008;80:517-23 pubmed publisher
    Clinically apparent mumps reinfection is considered extremely rare, but several cases have been suspected of reinfection in an out-patient clinic...
  4. Muhsen K, Shohat T, Aboudy Y, Mendelson E, Algor N, Anis E, et al. Sero-prevalence of mumps antibodies in subpopulations subsequently affected by a large scale mumps epidemic in Israel. Vaccine. 2011;29:3878-82 pubmed publisher
    Despite the high national vaccination coverage, a large outbreak of mumps occurred in Israel, in 2009-2010, with onset and heavy transmission in ultraorthodox Jewish communities and further country-wide spread...
  5. Yung C, Andrews N, Bukasa A, Brown K, Ramsay M. Mumps complications and effects of mumps vaccination, England and Wales, 2002-2006. Emerg Infect Dis. 2011;17:661-7; quiz 766 pubmed publisher
    We analyzed data from hospital admissions and enhanced mumps surveillance to assess mumps complications during the largest mumps outbreak in England and Wales, 2004-2005, and their association with mumps vaccination...
  6. Anderson L, Seward J. Mumps epidemiology and immunity: the anatomy of a modern epidemic. Pediatr Infect Dis J. 2008;27:S75-9 pubmed publisher
    The success of the measles, mumps, and rubella 2-dose vaccination program led public health officials in 1998 to set a goal to eliminate endemic transmission of mumps virus by 2010 in the United States...
  7. Yuk J, Ha K. Array-based spectral SPR biosensor: analysis of mumps virus infection. Methods Mol Biol. 2009;503:37-47 pubmed publisher
    ..gold arrays was modified with poly(diallyldimethylammonium chloride) and 11-mercap-toundecanoic acid to immobilize mumps virus...
  8. Bangor Jones R, Dowse G, Giele C, Van Buynder P, Hodge M, Whitty M. A prolonged mumps outbreak among highly vaccinated Aboriginal people in the Kimberley region of Western Australia. Med J Aust. 2009;191:398-401 pubmed
    To describe a prolonged outbreak of mumps in the Kimberley region of Western Australia in 2007-2008...
  9. Alp E, Cevahir F, Gokahmetoglu S, Demiraslan H, Doganay M. Prevaccination screening of health-care workers for immunity to measles, rubella, mumps, and varicella in a developing country: What do we save?. J Infect Public Health. 2012;5:127-32 pubmed publisher
    ..The HCWs were also screened for measles, rubella, mumps, and varicella (MMRV) using serological methods. One thousand two hundred and fifty-five HCWs were tested...

More Information

Publications93

  1. Vyse A, Gay N, Hesketh L, Pebody R, Morgan Capner P, Miller E. Interpreting serological surveys using mixture models: the seroepidemiology of measles, mumps and rubella in England and Wales at the beginning of the 21st century. Epidemiol Infect. 2006;134:1303-12 pubmed
    ..is applied to age-specific frequency distributions of quantitative results from serological surveys for measles, mumps and rubella using samples collected across the age range in England and Wales in 2000...
  2. McLean H, Fiebelkorn A, Temte J, Wallace G. Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep. 2013;62:1-34 pubmed
    ..of all current recommendations for the prevention of measles, rubella, congenital rubella syndrome (CRS), and mumps. The report presents the recent revisions adopted by the Advisory Committee on Immunization Practices (ACIP) on ..
  3. Fanoy E, Cremer J, Ferreira J, Dittrich S, van Lier A, Hahné S, et al. Transmission of mumps virus from mumps-vaccinated individuals to close contacts. Vaccine. 2011;29:9551-6 pubmed publisher
    During a recent mumps epidemic in the Netherlands caused by a genotype D mumps virus strain, we investigated the potential of vaccinated people to spread mumps disease to close contacts...
  4. Fu C, Liang J, Wang M. Matched case-control study of effectiveness of live, attenuated S79 mumps virus vaccine against clinical mumps. Clin Vaccine Immunol. 2008;15:1425-8 pubmed publisher
    b>Mumps virus infection is a potentially serious viral infection of childhood and early adulthood. In China, live, attenuated S(79) mumps virus vaccine has been licensed for pediatric use since 1990...
  5. Gemmill I. Mumps vaccine: is it time to re-evaluate our approach?. CMAJ. 2006;175:491-2 pubmed
  6. Bitsko R, Cortese M, Dayan G, Rota P, Lowe L, Iversen S, et al. Detection of RNA of mumps virus during an outbreak in a population with a high level of measles, mumps, and rubella vaccine coverage. J Clin Microbiol. 2008;46:1101-3 pubmed publisher
    The duration of mumps virus RNA detection was studied during a mumps outbreak in a highly vaccinated university population...
  7. Cortese M, Jordan H, Curns A, Quinlan P, Ens K, Denning P, et al. Mumps vaccine performance among university students during a mumps outbreak. Clin Infect Dis. 2008;46:1172-80 pubmed publisher
    The largest reported mumps outbreak at a US college in 19 years occurred in 2006 at a Kansas university with a 2-dose measles-mumps-rubella (MMR) vaccination policy...
  8. LeBaron C, Forghani B, Beck C, Brown C, Bi D, Cossen C, et al. Persistence of mumps antibodies after 2 doses of measles-mumps-rubella vaccine. J Infect Dis. 2009;199:552-60 pubmed publisher
    Since 1990, most US schoolchildren have received a second dose of measles-mumps-rubella vaccine (MMR2) at kindergarten entry. The objective of the present study was to evaluate the short- and long-term mumps immunogenicity of MMR2...
  9. Krause C, Eastick K, Ogilvie M. Real-time PCR for mumps diagnosis on clinical specimens--comparison with results of conventional methods of virus detection and nested PCR. J Clin Virol. 2006;37:184-9 pubmed
    Since November 2003, the UK has seen a dramatic rise in the number of mumps cases, resulting in increasing demands on virology laboratories to confirm mumps infection in a timely and efficient manner...
  10. Saika S, Kidokoro M, Kubonoya H, Ito K, Ohkawa T, Aoki A, et al. Development and biological properties of a new live attenuated mumps vaccine. Comp Immunol Microbiol Infect Dis. 2006;29:89-99 pubmed
    To develop a new live attenuated mumps vaccine, a wild mumps Y7 strain isolated from a patient who developed mild parotitis was treated with nitrosoguanidine and ultraviolet, followed by selection of a temperature-sensitive clone...
  11. Watson Creed G, Saunders A, Scott J, Lowe L, Pettipas J, Hatchette T. Two successive outbreaks of mumps in Nova Scotia among vaccinated adolescents and young adults. CMAJ. 2006;175:483-8 pubmed
    Before the widespread use of vaccine, mumps was the most common cause of viral meningitis (up to 10% of mumps infections)...
  12. Marin M, QUINLISK P, Shimabukuro T, Sawhney C, Brown C, LeBaron C. Mumps vaccination coverage and vaccine effectiveness in a large outbreak among college students--Iowa, 2006. Vaccine. 2008;26:3601-7 pubmed publisher
    Following implementation of a routine childhood two-dose measles-mumps-rubella vaccination strategy, mumps disease levels dropped dramatically in the US and an elimination goal was set for 2010...
  13. Lievano F, Galea S, Thornton M, Wiedmann R, Manoff S, Tran T, et al. Measles, mumps, and rubella virus vaccine (M-M-R™II): a review of 32 years of clinical and postmarketing experience. Vaccine. 2012;30:6918-26 pubmed publisher
    M-M-R™II (measles, mumps, and rubella virus vaccine live; Merck, Sharp, & Dohme Corp.) is indicated for simultaneous vaccination against measles, mumps, and rubella in individuals ? 12 months of age...
  14. Deeks S, Lim G, Simpson M, Gagné L, Gubbay J, Kristjanson E, et al. An assessment of mumps vaccine effectiveness by dose during an outbreak in Canada. CMAJ. 2011;183:1014-20 pubmed publisher
    This investigation was done to assess vaccine effectiveness of one and two doses of the measles, mumps and rubella (MMR) vaccine during an outbreak of mumps in Ontario...
  15. Vandermeulen C, Clement F, Roelants M, Van Damme P, Hoppenbrouwers K, Leroux Roels G. Evaluation of cellular immunity to mumps in vaccinated individuals with or without circulating antibodies up to 16 years after their last vaccination. J Infect Dis. 2009;199:1457-60 pubmed publisher
    In this observational study, mumps-specific in vitro lymphoproliferation was measured in 24 subjects with low antibody titers and 24 subjects with high antibody titers who received their last vaccine dose up to 16 years previously...
  16. Vainio K, Samdal H, Anestad G, Wedege E, Skutlaberg D, Bransdal K, et al. Detection of measles- and mumps-specific IgG antibodies in paired serum and oral fluid samples from Norwegian conscripts. Eur J Clin Microbiol Infect Dis. 2008;27:461-5 pubmed publisher
    The aim of this study was to measure the seroprevalence to mumps in Norwegian conscripts belonging to the first children vaccination cohorts that had been offered two doses of MMR vaccine...
  17. Gurgoze M, Yilmaz E, Godekmerdan A, Akça Z, Dogan Y, Akarsu S, et al. Seroprevalence of mumps, varicella and rubella antibodies in children 1-16 years of age in eastern Turkey. Turk J Pediatr. 2006;48:185-8 pubmed
    In this study, seroprevalence of mumps, varicella and rubella was investigated in 803 unvaccinated children in eastern Turkey whose ages ranged between 1 and 16 years...
  18. Miller C. Mumps resurgence prompts revised recommendations. Minn Med. 2007;90:41-3 pubmed
    b>Mumps outbreaks in 2006 served as a reminder that this often-overlooked, vaccine-preventable disease is still a threat. The outbreaks were concentrated in Iowa but affected several other states in the Midwest...
  19. Dayan G, Quinlisk M, Parker A, Barskey A, Harris M, Schwartz J, et al. Recent resurgence of mumps in the United States. N Engl J Med. 2008;358:1580-9 pubmed publisher
    The widespread use of a second dose of mumps vaccine among U.S. schoolchildren beginning in 1990 was followed by historically low reports of mumps cases...
  20. Wharton I, Chaudhry A, French M. A case of mumps epididymitis. Lancet. 2006;367:702 pubmed
  21. Vandana K, Arunkumar G, Bairy I. Role of laboratory in rapid diagnosis of atypical mumps. Braz J Infect Dis. 2010;14:201-2 pubmed
    Fairly large number of mumps virus infections present atypically without parotitis leading to delay in diagnosis and increased morbidity...
  22. Barskey A, Glasser J, LeBaron C. Mumps resurgences in the United States: A historical perspective on unexpected elements. Vaccine. 2009;27:6186-95 pubmed publisher
    In 2006 the United States experienced the largest nationwide mumps epidemic in 20 years, primarily affecting college dormitory residents...
  23. Takla A, Wichmann O, Klinc C, Hautmann W, Rieck T, Koch J. Mumps epidemiology in Germany 2007-11. Euro Surveill. 2013;18:20557 pubmed
    In Germany, mumps has been notifiable until 2013 only in the five Eastern federal states (EFS) of former East Germany...
  24. Xu P, Li Z, Sun D, Lin Y, Wu J, Rota P, et al. Rescue of wild-type mumps virus from a strain associated with recent outbreaks helps to define the role of the SH ORF in the pathogenesis of mumps virus. Virology. 2011;417:126-36 pubmed publisher
    b>Mumps virus (MuV) causes acute infections in humans. In recent years, MuV has caused epidemics among highly vaccinated populations. The largest outbreak in the U.S...
  25. Lemon K, Rima B, McQuaid S, Allen I, Duprex W. The F gene of rodent brain-adapted mumps virus is a major determinant of neurovirulence. J Virol. 2007;81:8293-302 pubmed
    Prior to the introduction of live-attenuated vaccines, mumps virus (MuV) was the leading cause of virus-induced meningitis...
  26. Johnson J, Grant K, Parks G. The paramyxoviruses simian virus 5 and mumps virus recruit host cell CD46 to evade complement-mediated neutralization. J Virol. 2009;83:7602-11 pubmed publisher
    ..Similar results were obtained for the closely related mumps virus (MuV), except that MuV particles derived from CHO-CD46 cells had higher C4b cofactor activity than SV5 ..
  27. dos Santos B, Stralioto S, Siqueira M, Ranieri T, Bercini M, Schermann M, et al. Prevalence of antibodies against measles, mumps, and rubella before and after vaccination of school-age children with three different triple combined viral vaccines, Rio Grande do Sul, Brazil, 1996. Rev Panam Salud Publica. 2006;20:299-306 pubmed
    We evaluated the seroprevalence for measles, mumps, and rubella in school-age children (6-12 years old) before and after the administration of three triple combined viral vaccines.
  28. Sulik A, Wojtkowska M, Oldak E. Elevated levels of MMP-9 and TIMP-1 in the cerebrospinal fluid of children with echovirus type 30 and mumps meningitis. Scand J Immunol. 2008;68:323-7 pubmed publisher
    ..Concentrations were measured by using an enzyme-linked immunosorbent assay (ELISA) in 16 children with mumps meningitis, in 25 children with echovirus type 30 meningitis and in a control group of 23 children without any CNS ..
  29. Rubin S, Link M, Sauder C, Zhang C, Ngo L, Rima B, et al. Recent mumps outbreaks in vaccinated populations: no evidence of immune escape. J Virol. 2012;86:615-20 pubmed publisher
    Recently, numerous large-scale mumps outbreaks have occurred in vaccinated populations...
  30. Ramondetti F, Sacco S, Comelli M, Bruno G, Falorni A, Iannilli A, et al. Type 1 diabetes and measles, mumps and rubella childhood infections within the Italian Insulin-dependent Diabetes Registry. Diabet Med. 2012;29:761-6 pubmed publisher
    ..A study investigating the incidence of Type 1 diabetes during 1996-1997 showed a higher notification of viral infections in the Pavia District. The aim was to confirm these results...
  31. Nelson G, Aguon A, Valencia E, Oliva R, Guerrero M, Reyes R, et al. Epidemiology of a mumps outbreak in a highly vaccinated island population and use of a third dose of measles-mumps-rubella vaccine for outbreak control--Guam 2009 to 2010. Pediatr Infect Dis J. 2013;32:374-80 pubmed publisher
    Despite high 2-dose measles-mumps-rubella (MMR) vaccine coverage, a large mumps outbreak occurred on the US Territory of Guam during 2009 to 2010, primarily in school-aged children.
  32. Ternavasio de la Vega H, Boronat M, Ojeda A, García Delgado Y, Angel Moreno A, Carranza Rodriguez C, et al. Mumps orchitis in the post-vaccine era (1967-2009): a single-center series of 67 patients and review of clinical outcome and trends. Medicine (Baltimore). 2010;89:96-116 pubmed publisher
    Since the introduction of the mumps vaccine, the age of appearance of mumps infection has shifted from children to adolescents and young adults, groups with a higher incidence of disease complications and sequelae...
  33. Waaijenborg S, Hahné S, Mollema L, Smits G, Berbers G, van der Klis F, et al. Waning of maternal antibodies against measles, mumps, rubella, and varicella in communities with contrasting vaccination coverage. J Infect Dis. 2013;208:10-6 pubmed publisher
    The combined measles, mumps, and rubella (MMR) vaccine has been successfully administered for >20 years. Because of this, protection by maternal antibodies in infants born to vaccinated mothers might be negatively affected.
  34. Vaidya S, Brown D, Jin L, Samuel D, Andrews N, Brown K. Development of a focus reduction neutralization test (FRNT) for detection of mumps virus neutralizing antibodies. J Virol Methods. 2010;163:153-6 pubmed publisher
    ..test (PRNT) is considered the "gold-standard" assay for measuring neutralizing antibodies for mumps, it is technically demanding, slow and requires large serum volumes, which limits its use for investigating mumps ..
  35. Sauder C, Vandenburgh K, Iskow R, Malik T, Carbone K, Rubin S. Changes in mumps virus neurovirulence phenotype associated with quasispecies heterogeneity. Virology. 2006;350:48-57 pubmed
    b>Mumps virus is a highly neurotropic virus with evidence of central nervous system invasion (CNS) in approximately half of all cases of infection...
  36. Li M, Schmitt P, Li Z, McCrory T, He B, Schmitt A. Mumps virus matrix, fusion, and nucleocapsid proteins cooperate for efficient production of virus-like particles. J Virol. 2009;83:7261-72 pubmed publisher
    ..To define mumps virus (MuV) proteins important for this process, viral proteins were expressed either singly or in combination in ..
  37. Heijstek M, van Gageldonk P, Berbers G, Wulffraat N. Differences in persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between children with rheumatic disease and healthy controls: a retrospective cross-sectional study. Ann Rheum Dis. 2012;71:948-54 pubmed publisher
    To compare the persistence of measles, mumps, rubella, diphtheria and tetanus antibodies between patients with juvenile idiopathic arthritis (JIA) and healthy controls.
  38. Barskey A, Schulte C, Rosen J, Handschur E, Rausch Phung E, Doll M, et al. Mumps outbreak in Orthodox Jewish communities in the United States. N Engl J Med. 2012;367:1704-13 pubmed publisher
    By 2005, vaccination had reduced the annual incidence of mumps in the United States by more than 99%, with few outbreaks reported...
  39. Cohen C, White J, Savage E, Glynn J, Choi Y, Andrews N, et al. Vaccine effectiveness estimates, 2004-2005 mumps outbreak, England. Emerg Infect Dis. 2007;13:12-7 pubmed
    The United Kingdom and United States have recently experienced large outbreaks of mumps, which raises concerns about vaccine effectiveness...
  40. Socan M, Berginc N. High seroprevalence of varicella, measles, mumps, rubella and pertussis antibodies in first-grade medical students. Wien Klin Wochenschr. 2008;120:422-6 pubmed publisher
    The aim of the study was to investigate seropositivity for five vaccine-preventable communicable diseases - varicella, measles, mumps, rubella and pertussis - in a sample of first-grade medical students.
  41. Atrasheuskaya A, Blatun E, Kulak M, Atrasheuskaya A, Karpov I, Rubin S, et al. Investigation of mumps vaccine failures in Minsk, Belarus, 2001-2003. Vaccine. 2007;25:4651-8 pubmed
    The purpose of this study was to investigate mumps vaccine failures (VF) in a highly vaccinated population of Minsk, Belarus, and to investigate a possible role for virus strain-specific immunity...
  42. Hashimoto H, Fujioka M, Kinumaki H. An office-based prospective study of deafness in mumps. Pediatr Infect Dis J. 2009;28:173-5 pubmed publisher
    Deafness is a rare but important complication of mumps virus infection. Its incidence has been estimated at 0.5 to 5...
  43. Onozuka D, Hashizume M. Effect of weather variability on the incidence of mumps in children: a time-series analysis. Epidemiol Infect. 2011;139:1692-700 pubmed publisher
    ..However, few studies have examined the impact of weather variability on mumps in children, despite the fact that children are considered particularly vulnerable to climate change...
  44. Dhiman N, Ovsyannikova I, Vierkant R, Pankratz V, Jacobson R, Poland G. Associations between cytokine/cytokine receptor single nucleotide polymorphisms and humoral immunity to measles, mumps and rubella in a Somali population. Tissue Antigens. 2008;72:211-20 pubmed publisher
    ..nucleotide polymorphisms (SNPs) using Illumina GoldenGate genotyping to determine associations with measles, mumps and rubella immunity. Overall, 61 significant associations (P < or = 0...
  45. Puri M, Lemon K, Duprex W, Rima B, Horvath C. A point mutation, E95D, in the mumps virus V protein disengages STAT3 targeting from STAT1 targeting. J Virol. 2009;83:6347-56 pubmed publisher
    b>Mumps virus, like other paramyxoviruses in the Rubulavirus genus, encodes a V protein that can assemble a ubiquitin ligase complex from cellular components, leading to the destruction of cellular signal transducer and activator of ..
  46. Masarani M, Wazait H, Dinneen M. Mumps orchitis. J R Soc Med. 2006;99:573-5 pubmed
    Although the incidence of mumps orchitis has dramatically declined since the introduction of the childhood vaccination programme, a sharp increase in reported cases of both mumps and mumps orchitis has been seen recently in the UK...
  47. Theeten H, Hutse V, Hens N, Yavuz Y, Hoppenbrouwers K, Beutels P, et al. Are we hitting immunity targets? The 2006 age-specific seroprevalence of measles, mumps, rubella, diphtheria and tetanus in Belgium. Epidemiol Infect. 2011;139:494-504 pubmed publisher
    ..Immunoglobulins against measles, mumps, rubella (MMR) and diphtheria at all available ages (1-65 years), and against tetanus in >40-year-olds, were ..
  48. Polgreen P, Bohnett L, Yang M, Pentella M, Cavanaugh J. A spatial analysis of the spread of mumps: the importance of college students and their spring-break-associated travel. Epidemiol Infect. 2010;138:434-41 pubmed publisher
    To characterize the association between county-level risk factors and the incidence of mumps in the 2006 Iowa outbreak, we used generalized linear mixed models with the number of mumps cases per county as the dependent variable...
  49. Schaffzin J, Pollock L, Schulte C, Henry K, Dayan G, Blog D, et al. Effectiveness of previous mumps vaccination during a summer camp outbreak. Pediatrics. 2007;120:e862-8 pubmed
    b>Mumps is a vaccine-preventable disease that may cause outbreaks. In July 2005, an outbreak of mumps occurred during a children's summer camp in upstate New York...
  50. Aytac S, Yalcin S, Cetin M, Yetgin S, Gumruk F, Tuncer M, et al. Measles, mumps, and rubella antibody status and response to immunization in children after therapy for acute lymphoblastic leukemia. Pediatr Hematol Oncol. 2010;27:333-43 pubmed publisher
    ..months before enrollment in this study were retrospectively analyzed regarding their antibody status for measles, mumps, and rubella, with the aim to demonstrate the seropositivity rate after treatment in the authors' group...
  51. Bonebrake A, Silkaitis C, Monga G, Galat A, Anderson J, Trad J, et al. Effects of mumps outbreak in hospital, Chicago, Illinois, USA, 2006. Emerg Infect Dis. 2010;16:426-32 pubmed publisher
    In 2006, nearly 6,000 mumps cases were reported in the United States, 795 of which occurred in Illinois. In Chicago, 1 healthcare institution experienced ongoing transmission for 4 weeks...
  52. Dominguez A, Plans P, Costa J, Torner N, Cardenosa N, Batalla J, et al. Seroprevalence of measles, rubella, and mumps antibodies in Catalonia, Spain: results of a cross-sectional study. Eur J Clin Microbiol Infect Dis. 2006;25:310-7 pubmed
    ..The objective of this study was to determine the prevalence of measles, rubella, and mumps antibodies in representative samples of the child and adult population of Catalonia and compare the findings to ..
  53. Wicker S, Rabenau H, Gottschalk R, Doerr H, Allwinn R. Seroprevalence of vaccine preventable and blood transmissible viral infections (measles, mumps, rubella, polio, HBV, HCV and HIV) in medical students. Med Microbiol Immunol. 2007;196:145-50 pubmed
    ..B-virus (HBV), hepatitis C-virus (HCV), human immunodeficiency virus (HIV), varicella zoster- (VZV), measles-, mumps-, rubella and polioviruses' type 1, 2 and 3 were performed. The results yielded, that 69...
  54. Park D, Nam M, Kim J, Kim H, Sohn J, Cho Y, et al. Mumps outbreak in a highly vaccinated school population: assessment of secondary vaccine failure using IgG avidity measurements. Vaccine. 2007;25:4665-70 pubmed
    From March to April 2006, an outbreak of mumps occurred in Gyeonggi, Korea...
  55. Snijders B, van Lier A, van de Kassteele J, Fanoy E, Ruijs W, Hulshof F, et al. Mumps vaccine effectiveness in primary schools and households, the Netherlands, 2008. Vaccine. 2012;30:2999-3002 pubmed publisher
    To estimate the mumps vaccine effectiveness (VE) during a large genotype D mumps outbreak, we conducted a cross-sectional study in eight primary schools and associated households in the Netherlands...
  56. Alirezaie B, Aghaiypour K, Shafyi A. Genetic characterization of RS-12 (S-12), an Iranian isolate of mumps virus, by sequence analysis and comparative genomics of F, SH, and HN genes. J Med Virol. 2008;80:702-10 pubmed publisher
    RS-12 mumps virus strain was isolated in 1986, in monkey kidney cells, from the throat-washing of an Iranian patient and developed to RS-12 vaccine by serial passage of the pathogen in MRC-5 cells...
  57. McIntyre P, Leask J. Improving uptake of MMR vaccine. BMJ. 2008;336:729-30 pubmed publisher
  58. Hviid A, Rubin S, Mühlemann K. Mumps. Lancet. 2008;371:932-44 pubmed publisher
    b>Mumps is a common childhood infection caused by the mumps virus. The hallmark of infection is swelling of the parotid gland...
  59. Sulik A, Wojtkowska M, Rozkiewicz D, Oldak E. Increase in adhesion molecules in cerebrospinal fluid of children with mumps and mumps meningitis. Scand J Immunol. 2006;64:420-4 pubmed
    ..sICAM-1) and leucocyte-originated soluble L-selectin (sL-selectin) in cerebrospinal fluid (CSF) of children with mumps meningitis (mononuclear pleocytosis, n = 33) and mumps (absence of pleocytosis, n = 9) were compared with values ..
  60. Saffar M, Ajami A, Khalilian A, Saffar H. The impact of maternal measles-rubella immunization on the 12-month-old infant's immune response to measles-mumps-rubella vaccine immunogenicity. Eur J Clin Microbiol Infect Dis. 2009;28:845-7 pubmed publisher
    ..MR) vaccination before pregnancy on the persistence of passive immunity against MR in their infant before measles-mumps-rubella (MMR) immunization and the effects on the immunogenicity of MMR vaccine...
  61. Hanaoka M, Hisano M, Watanabe N, Sugawara K, Kambe Y, Kanda E, et al. Changes in the prevalence of the measles, rubella, varicella-zoster, and mumps virus antibody titers in Japanese pregnant women. Vaccine. 2013;31:2343-7 pubmed publisher
    ..4 via the neutralization test [NT]), rubella (? 16 via the hemagglutination inhibition [HI]), and varicella and mumps (plus minus or negative on the enzyme-linked immunosorbent assay [EIA]) indicated that the rates of necessity for ..
  62. Sanz J, Mosquera M, Echevarria J, Fernandez M, Herranz N, Palacios G, et al. Sensitivity and specificity of immunoglobulin G titer for the diagnosis of mumps virus in infected patients depending on vaccination status. APMIS. 2006;114:788-94 pubmed
    The aim of the study was to evaluate the usefulness of serological detection of mumps IgM and titration of IgG in patients with acute parotitis according to their vaccination status...
  63. Tesovic G, Lesnikar V. Aseptic meningitis after vaccination with L-Zagreb mumps strain--virologically confirmed cases. Vaccine. 2006;24:6371-3 pubmed
  64. Bricks L, Sato H, Oselka G. Varicella vaccines and measles, mumps, rubella, and varicella vaccine. J Pediatr (Rio J). 2006;82:S101-8 pubmed
    To present an up-to-date review of studies investigating the efficacy, adverse events and vaccination regimens of the varicella vaccine and the new presentation combined with the vaccine for measles, mumps and rubella.
  65. LeBlanc J, Pettipas J, Davidson R, Tipples G, Hiebert J, Hatchette T. Detection of mumps virus RNA by real-time one-step reverse transcriptase PCR using the LightCycler platform. J Clin Microbiol. 2008;46:4049-51 pubmed publisher
    A real-time reverse transcriptase PCR (RT-PCR) assay that targeted both the mumps virus F gene and human RNase P in clinical samples was adapted for use with the LightCycler platform...
  66. Cortese M, Barskey A, Tegtmeier G, Zhang C, Ngo L, Kyaw M, et al. Mumps antibody levels among students before a mumps outbreak: in search of a correlate of immunity. J Infect Dis. 2011;204:1413-22 pubmed publisher
    In 2006, a mumps outbreak occurred on a university campus despite ? 95% coverage of students with 2 doses of measles-mumps-rubella (MMR) vaccine...
  67. Brockhoff H, Mollema L, Sonder G, Postema C, van Binnendijk R, Kohl R, et al. Mumps outbreak in a highly vaccinated student population, The Netherlands, 2004. Vaccine. 2010;28:2932-6 pubmed publisher
    In September 2004 a mumps outbreak occurred at an international hotel school in The Netherlands. We investigated this outbreak to identify risk factors for mumps...
  68. Cui A, Myers R, Xu W, Jin L. Analysis of the genetic variability of the mumps SH gene in viruses circulating in the UK between 1996 and 2005. Infect Genet Evol. 2009;9:71-80 pubmed publisher
    Genetic analysis (genotyping) of mumps viruses has been applied to the molecular epidemiology of mumps for over 10 years in the UK...
  69. Davidkin I, Jokinen S, Broman M, Leinikki P, Peltola H. Persistence of measles, mumps, and rubella antibodies in an MMR-vaccinated cohort: a 20-year follow-up. J Infect Dis. 2008;197:950-6 pubmed publisher
    The persistence of antibodies against measles, mumps, and rubella induced by the measles-mumps-rubella (MMR) vaccine and the kinetics of antibody decline after the second MMR vaccine dose were studied in the same cohort for 20 years.
  70. Schmid D, Pichler A, Wallenko H, Holzmann H, Popow Kraupp T, Allerberger F. Mumps outbreak affecting adolescents and young adults in Austria, 2006: update. Euro Surveill. 2006;11:E060706.2 pubmed
  71. Shourie S, Jackson C, Cheater F, Bekker H, Edlin R, Tubeuf S, et al. A cluster randomised controlled trial of a web based decision aid to support parents' decisions about their child's Measles Mumps and Rubella (MMR) vaccination. Vaccine. 2013;31:6003-10 pubmed publisher
    ..To evaluate the effectiveness of a web based decision aid versus a leaflet versus, usual practice in reducing parents' decisional conflict for the first dose MMR vaccination decision. The, impact on MMR vaccine uptake was also explored...
  72. Singh R, Mostafid H, Hindley R. Measles, mumps and rubella -- the urologist's perspective. Int J Clin Pract. 2006;60:335-9 pubmed
    ..has been a decline in the uptake of the MMR vaccine and a significant increase the number of reported case of mumps. This condition has number of important extrasalivary manifestations including mumps epididymo-orchitits...
  73. Stowe J, Andrews N, Taylor B, Miller E. No evidence of an increase of bacterial and viral infections following Measles, Mumps and Rubella vaccine. Vaccine. 2009;27:1422-5 pubmed publisher
    ..increase there appeared to be a reduced risk of severe bacterial infection in the three months following Measles, Mumps and Rubella vaccine (MMR)...
  74. Ahlgren C, Oden A, Toren K, Andersen O. Multiple sclerosis incidence in the era of measles-mumps-rubella mass vaccinations. Acta Neurol Scand. 2009;119:313-20 pubmed publisher
    ..Following national Swedish vaccination programs, measles sharply declined in the 1970s, and measles, mumps, and rubella were virtually eliminated in cohorts born from 1981.
  75. Bonnet M, Dutta A, Weinberger C, Plotkin S. Mumps vaccine virus strains and aseptic meningitis. Vaccine. 2006;24:7037-45 pubmed
    b>Mumps immunization can easily be included in national schedules, particularly if combined with measles or measles and rubella vaccines, but debate continues concerning the relative safety of various licensed mumps vaccine strains...
  76. Rubin S, Qi L, Audet S, Sullivan B, Carbone K, Bellini W, et al. Antibody induced by immunization with the Jeryl Lynn mumps vaccine strain effectively neutralizes a heterologous wild-type mumps virus associated with a large outbreak. J Infect Dis. 2008;198:508-15 pubmed publisher
    Recent mumps outbreaks in older vaccinated populations were caused primarily by genotype G viruses, which are phylogenetically distinct from the genotype A vaccine strains used in the countries affected by the outbreaks...
  77. Greenaway C, Dongier P, Boivin J, Tapiero B, Miller M, Schwartzman K. Susceptibility to measles, mumps, and rubella in newly arrived adult immigrants and refugees. Ann Intern Med. 2007;146:20-4 pubmed
    Despite effective vaccination programs for measles, mumps, and rubella in the United States and Canada, outbreaks continue to occur in susceptible subgroups, such as foreign-born persons.
  78. Greenland K, Whelan J, Fanoy E, Borgert M, Hulshof K, Yap K, et al. Mumps outbreak among vaccinated university students associated with a large party, the Netherlands, 2010. Vaccine. 2012;30:4676-80 pubmed publisher
    We investigated a mumps outbreak within a highly vaccinated university student population in the Netherlands by conducting a retrospective cohort study among members of university societies in Delft, Leiden and Utrecht...
  79. Davis N, McGuire B, Mahon J, Smyth A, O Malley K, Fitzpatrick J. The increasing incidence of mumps orchitis: a comprehensive review. BJU Int. 2010;105:1060-5 pubmed publisher
    There has been a recent increase in mumps orchitis among pubertal and postpubertal males...
  80. Demicheli V, Rivetti A, Debalini M, Di Pietrantonj C. Vaccines for measles, mumps and rubella in children. Cochrane Database Syst Rev. 2012;:CD004407 pubmed publisher
    b>Mumps, measles and rubella (MMR) are serious diseases that can lead to potentially fatal illness, disability and death...
  81. Kancherla V, Hanson I. Mumps resurgence in the United States. J Allergy Clin Immunol. 2006;118:938-41 pubmed
    The recent mumps epidemic in the central United States has generated a large amount of public concern...
  82. Latner D, McGrew M, Williams N, Lowe L, Werman R, Warnock E, et al. Enzyme-linked immunospot assay detection of mumps-specific antibody-secreting B cells as an alternative method of laboratory diagnosis. Clin Vaccine Immunol. 2011;18:35-42 pubmed publisher
    Although high measles, mumps, and rubella (MMR) vaccination coverage has been successful in dramatically reducing mumps disease in the United States, mumps (re)infections occasionally occur in individuals who have been either previously ..
  83. Celikbas A, Ergonul O, Aksaray S, Tuygun N, Esener H, Tanir G, et al. Measles, rubella, mumps, and varicella seroprevalence among health care workers in Turkey: is prevaccination screening cost-effective?. Am J Infect Control. 2006;34:583-7 pubmed
    To investigate the immune status of health care workers (HCWs) against measles, rubella, mumps, and varicella zoster (MMRV) in Turkey and to define an appropriate vaccination program among HCWs.
  84. Nagai T, Okafuji T, Miyazaki C, Ito Y, Kamada M, Kumagai T, et al. A comparative study of the incidence of aseptic meningitis in symptomatic natural mumps patients and monovalent mumps vaccine recipients in Japan. Vaccine. 2007;25:2742-7 pubmed
    To compare the incidence of aseptic meningitis associated with symptomatic natural mumps infection and in mumps vaccine recipients, we conducted a prospective comparative study...