fowlpox

Summary

Summary: A poxvirus infection of poultry and other birds characterized by the formation of wart-like nodules on the skin and diphtheritic necrotic masses (cankers) in the upper digestive and respiratory tracts.

Top Publications

  1. Wang J, Meers J, Spradbrow P, Robinson W. Evaluation of immune effects of fowlpox vaccine strains and field isolates. Vet Microbiol. 2006;116:106-19 pubmed
    The immune effects of fowlpox virus (FPV) field isolates and vaccine strains were evaluated in chickens infected at the age of 1 day and 6 weeks...
  2. Culyba M, Hwang Y, Hu J, Minkah N, Ocwieja K, Bushman F. Metal cofactors in the structure and activity of the fowlpox resolvase. J Mol Biol. 2010;399:182-95 pubmed publisher
    ..Here we report studies of the influence of metal cofactors on the activity and structure of the resolvase of fowlpox virus, which provides a tractable model for in vitro studies...
  3. Diallo I, Taylor J, Gibson J, Hoad J, de Jong A, Hewitson G, et al. Diagnosis of a naturally occurring dual infection of layer chickens with fowlpox virus and gallid herpesvirus 1 (infectious laryngotracheitis virus). Avian Pathol. 2010;39:25-30 pubmed publisher
    An outbreak of acute respiratory disease in layers was diagnosed as being of dual nature due to fowlpox and infectious laryngotracheitis using a multidisciplinary approach including virus isolation, histopathology, electron microscopy ..
  4. Butter C, Sturman T, Baaten B, Davison T. Protection from infectious bursal disease virus (IBDV)-induced immunosuppression by immunization with a fowlpox recombinant containing IBDV-VP2. Avian Pathol. 2003;32:597-604 pubmed
    ..These results indicate that measurement of immunosuppression could be a useful strategy for assessing the efficacy of vaccines to protect against the consequences of IBDV infection...
  5. Bublot M, Pritchard N, Cruz J, Mickle T, Selleck P, Swayne D. Efficacy of a fowlpox-vectored avian influenza H5 vaccine against Asian H5N1 highly pathogenic avian influenza virus challenge. Avian Dis. 2007;51:498-500 pubmed
    A recombinant fowlpox-avian influenza (AI) H5 vaccine (rFP-AIV-HS) expressing the hemagglutinin of the A/turkey/Ireland/1378/83 H5N8 AI isolate has been used in Central America since 1998 to control H5N2 low pathogenicity AI...
  6. Davidson I, Shkoda I, Perk S. Integration of the reticuloendotheliosis virus envelope gene into the poultry fowlpox virus genome is not universal. J Gen Virol. 2008;89:2456-60 pubmed publisher
    b>Fowlpox virus (FWPV) is found worldwide in poultry and wild birds...
  7. Taylor J, Paoletti E. Fowlpox virus as a vector in non-avian species. Vaccine. 1988;6:466-8 pubmed
    ..We have taken advantage of this restricted host range in fowlpox virus to engineer recombinant vector viruses for use in the poultry industry and in vaccination of non-avian ..
  8. Singh P, Schnitzlein W, Tripathy D. Construction and characterization of a fowlpox virus field isolate whose genome lacks reticuloendotheliosis provirus nucleotide sequences. Avian Dis. 2005;49:401-8 pubmed
    b>Fowlpox virus (FWPV) has been isolated from vaccinated chicken flocks during subsequent fowlpox outbreaks that were characterized by a high degree of mortality and significant economic losses...
  9. Webster D, Dunachie S, McConkey S, Poulton I, Moore A, Walther M, et al. Safety of recombinant fowlpox strain FP9 and modified vaccinia virus Ankara vaccines against liver-stage P. falciparum malaria in non-immune volunteers. Vaccine. 2006;24:3026-34 pubmed
    ..We report on two such vaccine constructs, modified vaccinia virus Ankara and FP9 (an attenuated fowlpox virus) both expressing the pre-erythrocytic malaria antigen thrombospondin-related adhesion protein and a string ..

More Information

Publications83

  1. Boyle D, Heine H. Recombinant fowlpox virus vaccines for poultry. Immunol Cell Biol. 1993;71 ( Pt 5):391-7 pubmed
    ..of recombinant vaccinia viruses have been readily adapted to the construction of recombinant viruses based on fowlpox virus (rFPV)...
  2. Srinivasan V, Schnitzlein W, Tripathy D. Fowlpox virus encodes a novel DNA repair enzyme, CPD-photolyase, that restores infectivity of UV light-damaged virus. J Virol. 2001;75:1681-8 pubmed
    b>Fowlpox virus (FPV), a pathogen of poultry, can persist in desiccated scabs shed from infected hosts...
  3. Singh P, Schnitzlein W, Tripathy D. Reticuloendotheliosis virus sequences within the genomes of field strains of fowlpox virus display variability. J Virol. 2003;77:5855-62 pubmed
    Nine field strains of fowlpox virus (FPV) isolated during a 24-year span from geographically diverse outbreaks of fowlpox in the United States were screened for the presence of reticuloendotheliosis virus (REV) sequences in their genomes ..
  4. Afonso C, Tulman E, Lu Z, Zsak L, Kutish G, Rock D. The genome of fowlpox virus. J Virol. 2000;74:3815-31 pubmed
    Here we present the genomic sequence, with analysis, of a pathogenic fowlpox virus (FPV). The 288-kbp FPV genome consists of a central coding region bounded by identical 9...
  5. Chen H, Shang Y, Yao H, Cui B, Zhang H, Wang Z, et al. Immune responses of chickens inoculated with a recombinant fowlpox vaccine coexpressing HA of H9N2 avain influenza virus and chicken IL-18. Antiviral Res. 2011;91:50-6 pubmed publisher
    ..Here, we developed a recombinant fowlpox virus (rFPV-HA) expressing the haemagglutinin (HA) gene of the A/CH/JY/1/05 (H9N2) influenza virus and a ..
  6. Ogawa R, Yanagida N, Saeki S, Saito S, Ohkawa S, Gotoh H, et al. Recombinant fowlpox viruses inducing protective immunity against Newcastle disease and fowlpox viruses. Vaccine. 1990;8:486-90 pubmed
    The haemagglutinin-neuraminidase gene of Newcastle disease virus was inserted into a non-essential region of the fowlpox virus genome and expressed under control of the vaccinia virus 7.5 kDa polypeptide gene promoter...
  7. Banadyga L, Veugelers K, Campbell S, Barry M. The fowlpox virus BCL-2 homologue, FPV039, interacts with activated Bax and a discrete subset of BH3-only proteins to inhibit apoptosis. J Virol. 2009;83:7085-98 pubmed publisher
    ..Interestingly, the avipoxviruses, which include fowlpox and canarypox virus, are the only poxviruses known to encode proteins with obvious Bcl-2 sequence homology...
  8. Karaca K, Sharma J, Winslow B, Junker D, Reddy S, Cochran M, et al. Recombinant fowlpox viruses coexpressing chicken type I IFN and Newcastle disease virus HN and F genes: influence of IFN on protective efficacy and humoral responses of chickens following in ovo or post-hatch administration of recombinant viruses. Vaccine. 1998;16:1496-503 pubmed
    ..Chickens vaccinated with FPV coexpressing IFN and NDV genes produced less antibodies against NDV in comparison with chickens vaccinated with FPV expressing NDV genes...
  9. Isa G, Pfister K, Kaaden O, Czerny C. Development of a monoclonal blocking ELISA for the detection of antibodies against fowlpox virus. J Vet Med B Infect Dis Vet Public Health. 2002;49:21-3 pubmed
    To provide a fast and easy method to detect antibodies against fowlpox virus (FWPV) particularly in high numbers of chicken sera we established a monoclonal blocking enzyme-linked immunosorbent assay (ELISA)...
  10. Mishra S, Mallick B. Restriction fragment analysis of fowlpox virus using Bgl I, Bam HI, Hha I and Sma I restriction endonucleases. Indian J Exp Biol. 1996;34:959-63 pubmed
    b>Fowlpox virus vaccine strain and two field isolates collected from out breaks of disease were purified from cell culture using sucrose gradient ultracentrifugation...
  11. Li G, Hong Q, Ren Y, Lillehoj H, He C, Ren X. Development of FPV140 antigen-specific ELISA differentiating fowlpox virus isolates from all other viral pathogens of avian origin. Poult Sci. 2012;91:2507-11 pubmed
    The FPV140 gene encodes an envelope protein of fowlpox virus (FPV)...
  12. Hauck R, Prusas C, Hafez H, Lüschow D. Quantitative PCR as a tool to determine the reticuloendotheliosis virus-proviral load of fowl poxvirus. Avian Dis. 2009;53:211-5 pubmed
    ..201. Generally, the method overestimated the relative amount of REV-proviral DNA. Skin lesions from fowlpox outbreaks were investigated with the multiplex qPCR. The FPV:REV ratio was between 1:0.803 and 1:1...
  13. Joshi R, Shakya S. Rapid diagnosis of fowl pox with coagglutination assay. Trop Anim Health Prod. 1997;29:147-50 pubmed
    ..The test is easy to perform and rapid as the positive results can be read within 15 seconds. ..
  14. Wambura P, Mzula A. A novel rapid direct haemagglutination-inhibition assay for measurements of humoral immune response against non-haemagglutinating Fowlpox virus strains in vaccinated chickens. Heliyon. 2017;3:e00428 pubmed publisher
    b>Fowlpox (FP) is a serious disease in chickens caused by Fowlpox virus (FPV)...
  15. Gimeno I, Cortes A, Faiz N, Hernandez Ortiz B, Guy J, Hunt H, et al. Evaluation of the Protection Efficacy of a Serotype 1 Marek's Disease Virus-Vectored Bivalent Vaccine Against Infectious Laryngotracheitis and Marek's Disease. Avian Dis. 2015;59:255-62 pubmed publisher
    ..In recent years, the use of recombinant DNA-derived vaccines using turkey herpesvirus (HVT) and fowlpox virus has expanded, as they protect not only against the vector used but also against LT...
  16. Srinivasan V, Schnitzlein W, Tripathy D. A consideration of previously uncharacterized fowl poxvirus unidirectional and bidirectional late promoters for inclusion in homologous recombinant vaccines. Avian Dis. 2003;47:286-95 pubmed
    ..4-fold less efficient, both of these promoters, P174 and P190, should be satisfactory for directing the expression of poultry pathogen genes inserted into the genomes of FPV recombinant vaccines. ..
  17. Saini S, Maiti N, Sharma S. Immune response of chicks to oral vaccination with combined extra- and intracellular fowl pox viruses. Trop Anim Health Prod. 1990;22:165-9 pubmed
    ..05) than the control birds one week after revaccination. The serum haemolytic complement activity in both the vaccinated groups was significantly lower (P less than 0.05) than the control birds. ..
  18. Tadese T, Reed W. Detection of specific reticuloendotheliosis virus sequence and protein from REV-integrated fowlpox virus strains. J Virol Methods. 2003;110:99-104 pubmed
  19. Bickerton E, Keep S, Britton P. Reverse Genetics System for the Avian Coronavirus Infectious Bronchitis Virus. Methods Mol Biol. 2017;1602:83-102 pubmed publisher
    ..Infectious recombinant IBVs are generated in situ following the transfection of vaccinia virus DNA, containing the modified IBV cDNA, into cells infected with a recombinant fowlpox virus expressing T7 DNA-dependant RNA polymerase.
  20. Illiano E, Bissa M, Paolini F, Zanotto C, De Giuli Morghen C, Franconi R, et al. Prime-boost therapeutic vaccination in mice with DNA/DNA or DNA/Fowlpox virus recombinants expressing the Human Papilloma Virus type 16 E6 and E7 mutated proteins fused to the coat protein of Potato virus X. Virus Res. 2016;225:82-90 pubmed publisher
    ..After verifying the correct expression of E6F47RCP and E7GGGCP inserted into DNA and Fowlpox virus recombinants by Western blotting and immunofluorescence, their combined use was evaluated for therapy in a ..
  21. Peleg B, Samina I, Brenner J. Vaccination of chickens with live fowl pox (FP) vaccine in oil. Zentralbl Veterinarmed B. 1993;40:522-4 pubmed
    ..Incorporation of live FP vaccine in two different kinds of commercial Newcastle disease (ND) killed vaccine in oil, was shown to endow full protection following SC administration. ..
  22. Tanizaki E, Horiuchi T, Niikura M, Mikami T, Wakamiya N. Detection of fowlpox virus DNA by in situ hybridization using a biotinylated probe. Avian Dis. 1990;34:374-80 pubmed
    In situ hybridization was applied to detect fowlpox virus (FPV) DNA in formalin-fixed paraffin-embedded sections of the skin from infected chickens by using a biotinylated probe and a streptavidin-alkalinephosphatase conjugate...
  23. Anasir M, Caria S, Skinner M, Kvansakul M. Structural basis of apoptosis inhibition by the fowlpox virus protein FPV039. J Biol Chem. 2017;292:9010-9021 pubmed publisher
    ..One such viral prosurvival protein is the fowlpox virus protein FPV039, which is a potent apoptosis inhibitor, but the precise molecular mechanism by which FPV039 ..
  24. Buttigieg K, Laidlaw S, Ross C, Davies M, Goodbourn S, Skinner M. Genetic screen of a library of chimeric poxviruses identifies an ankyrin repeat protein involved in resistance to the avian type I interferon response. J Virol. 2013;87:5028-40 pubmed publisher
    ..We show that the prototypic avipoxvirus, fowlpox virus (FWPV), is highly resistant to the antiviral effects of avian IFN...
  25. Barreda C. Relationship Between Values of Fowlpox ELISA and the Presence of "Takes" After Vaccination. Avian Dis. 2016;60:67-9 pubmed publisher
    Values from an ELISA for evaluating the immune response induced by a commercial vaccine against fowlpox virus and the lesion at the site of inoculation (i.e., swelling of the skin or a pox where the vaccine was applied) were compared...
  26. Offerman K, Deffur A, Carulei O, Wilkinson R, Douglass N, Williamson A. Six host-range restricted poxviruses from three genera induce distinct gene expression profiles in an in vivo mouse model. BMC Genomics. 2015;16:510 pubmed publisher
    ..poxvirus species from three genera, namely Lumpy Skin Disease virus (LSDV), Canarypox virus (CNPV), Fowlpox virus (FWPV), modified vaccinia Ankara (MVA) and two novel South African avipoxviruses, Feral Pigeonpox virus (..
  27. Bissa M, Quaglino E, Zanotto C, Illiano E, Rolih V, Pacchioni S, et al. Protection of mice against the highly pathogenic VVIHD-J by DNA and fowlpox recombinant vaccines, administered by electroporation and intranasal routes, correlates with serum neutralizing activity. Antiviral Res. 2016;134:182-191 pubmed publisher
    ..In this study, DNA and fowlpox (FP) recombinants that expressed the VV L1R, A27L, A33R, and B5R genes were generated (4DNAmix, 4FPmix, ..
  28. Biswas S, Jana C, Chand K, Rehman W, Mondal B. Detection of fowl poxvirus integrated with reticuloendotheliosis virus sequences from an outbreak in backyard chickens in India. Vet Ital. 2011;47:147-53 pubmed
    ..In the present case, fowl pox has been observed to have persisted for about three years in fowl that were reared in backyard systems in villages...
  29. Li J, Yang T, Xu Q, Sun E, Feng Y, Lv S, et al. DNA vaccine prime and recombinant FPV vaccine boost: an important candidate immunization strategy to control bluetongue virus type 1. Appl Microbiol Biotechnol. 2015;99:8643-52 pubmed publisher
    ..Therefore, the need for an effective vaccine against BTV is urgent. In this study, DNA vaccines and recombinant fowlpox virus (rFPV) vaccines expressing VP2 alone or VP2 in combination with VP5 or co-expressing the VP2 and VP5 ..
  30. Le Loc h G, Paul M, Camus Bouclainville C, Bertagnoli S. Outbreaks of Pox Disease Due to Canarypox-Like and Fowlpox-Like Viruses in Large-Scale Houbara Bustard Captive-Breeding Programmes, in Morocco and the United Arab Emirates. Transbound Emerg Dis. 2016;63:e187-e196 pubmed publisher
    ..Molecular typing revealed that infections were mostly due to canarypox-like viruses in Morocco while fowlpox-like viruses were predominant in the United Arab Emirates...
  31. Ostrowski S, Dorrestein G, Ancrenaz M, Saint Jalme M. Debilitating cutaneous poxvirus lesions on two captive houbara bustards (Chlamydotis undulata). Avian Dis. 1995;39:907-11 pubmed
    ..Progressive leg lesions were extensive and interfered with walking, significantly debilitating the birds. Successful excisions of these lesions were performed...
  32. Barbour E, Hamadeh S, Hilan C, Abbas S. Comparison of immunity and resistance to diseases in male and female poultry breeders in Lebanon. Trop Anim Health Prod. 1995;27:65-70 pubmed
    ..Immune injuries, following vaccination, were observed in 85% of the males compared to none of the females. The immune injuries included appearance of facial papules, vesicles, and reddish brown to black scabs...
  33. Oros J, Rodriguez F, Rodriguez J, Bravo C, Fernandez A. Debilitating cutaneous poxvirus infection in a Hodgson's grandala (Grandala coelicolor). Avian Dis. 1997;41:481-3 pubmed
    ..Electron microscopy revealed numerous pox virions in the inclusion bodies. This is the first report of cutaneous poxvirus infection in a Hodgson's grandala...
  34. Tanizaki E, Kotani T, Odagiri Y, Horiuchi T. Pathologic changes in chickens caused by intravenous inoculation with fowlpox virus. Avian Dis. 1989;33:333-9 pubmed
    Twenty chickens were inoculated intravenously with fowlpox (FP) virus, and clinical and pathological examinations were carried out chronologically...
  35. Gao Y, Wang L, Huang B, Song M, Cui Y. [Self-excising reporter gene in recombinant Fowlpox virus expressing H5 hemagglutinin gene of influenza A virus using Cre-loxp systerm]. Wei Sheng Wu Xue Bao. 2007;47:537-9 pubmed
    ..Then delivery vector was constructed by subcloning hemagglutinin gene of subtype H5 and GFP gene into fowlpox virus recombinant arm...
  36. Docherty D, Long R, Flickinger E, Locke L. Isolation of poxvirus from debilitating cutaneous lesions on four immature grackles (Quiscalus sp.). Avian Dis. 1991;35:244-7 pubmed
    ..Phaenicia calliphoridae (blowfly) larvae were found in one of the pox nodules, raising the possibility of mechanical transmission of the virus by contaminated adult blowflies...
  37. Samour J, Cooper J. Avian pox in birds of prey (order Falconiformes) in Bahrain. Vet Rec. 1993;132:343-5 pubmed
    ..Quarantine and general hygiene procedures were also used as an integral part of the management and control of the disease...
  38. Hess C, Maegdefrau Pollan B, Bilic I, Liebhart D, Richter S, Mitsch P, et al. Outbreak of cutaneous form of poxvirus on a commercial turkey farm caused by the species fowlpox. Avian Dis. 2011;55:714-8 pubmed
    ..of the poxvirus species was carried out by PCR and sequencing, revealing an infection with the species fowlpox. Layers in vicinity of the turkey farm that also were affected by fowlpox were considered as potential source of ..
  39. Lee L, Witter R, Reddy S, Wu P, Yanagida N, Yoshida S. Protection and synergism by recombinant fowl pox vaccines expressing multiple genes from Marek's disease virus. Avian Dis. 2003;47:549-58 pubmed
    ..This synergism between rFPV/gB1gIgEUL32 and HVT indicates additional genes yet to be discovered in HVT may be responsible for the enhancement...
  40. Sharma J, Zhang Y, Jensen D, Rautenschlein S, Yeh H. Field trial in commercial broilers with a multivalent in ovo vaccine comprising a mixture of live viral vaccines against Marek's disease, infectious bursal disease, Newcastle disease, and fowl pox. Avian Dis. 2002;46:613-22 pubmed
    ..19%; FPV, 86% vs. 0%. The successful use of MIV under field conditions expands the usefulness of the in ovo technology for poultry...
  41. Ramsay A, Leong K, Ramshaw I. DNA vaccination against virus infection and enhancement of antiviral immunity following consecutive immunization with DNA and viral vectors. Immunol Cell Biol. 1997;75:382-8 pubmed
    ..of vaccine antigen encoded in DNA plasmids followed by a booster with the same antigen encoded in recombinant fowlpox virus vectors...
  42. Thiel T, Whiteman N, Tirape A, Baquero M, Cedeno V, Walsh T, et al. Characterization of canarypox-like viruses infecting endemic birds in the Galápagos Islands. J Wildl Dis. 2005;41:342-53 pubmed
    ..chain reaction-based method for identification and discrimination of avipoxvirus strains similar to the fowlpox or canarypox viruses...
  43. Lamien C, Mans J, Meda A, Couacy Hymann E, Romito M, Ouedraogo A, et al. In ovo inhibition of fowlpoxvirus replication by a gall extract from Guiera senegalensis. Avian Pathol. 2005;34:127-32 pubmed
    ..Three viral isolates were obtained from suspected fowlpox cases after passage in embryonating chicken eggs and their poxviral identity confirmed by electron microscopy...
  44. Hitchner S. History of biological control of poultry diseases in the USA. Avian Dis. 2004;48:1-8 pubmed
  45. Fallavena L, Rodrigues N, Moraes H, Salle C, da Silva A, Nascimento V, et al. Squamous cell carcinoma-like and pox lesions occurring simultaneously in chorioallantoic membranes of chicken embryos inoculated with materials from squamous cell carcinoma and pox lesions in broiler chickens. Avian Dis. 1997;41:469-71 pubmed
    ..This finding was unexpected and may shed some light on the etiology of SCC...
  46. Pace L, Chengappa M, Greer S, Alderson C. Isolation of Erysipelothrix rhusiopathiae from a red-tailed hawk (Buteo jamaicensis) with a concurrent pox virus infection. J Wildl Dis. 1987;23:671-3 pubmed
    ..The hawk had been housed on a farm with domestic turkeys, providing a possible source of the E. rhusiopathiae...
  47. Gustafson C, Bickford A, Cooper G, Charlton B. Sticktight fleas associated with fowl pox in a backyard chicken flock in California. Avian Dis. 1997;41:1006-9 pubmed
    ..Also noted histologically in this region were epidermal hyperplasia and ballooned epidermal cells containing intracytoplasmic inclusions indicative of fowl poxvirus...
  48. Huw Lee L, Hwa Lee K. Application of the polymerase chain reaction for the diagnosis of fowl poxvirus infection. J Virol Methods. 1997;63:113-9 pubmed
    ..The identity of the amplification products from the tissue specimen preparations was determined further by using a simple, rapid procedure in which an internally nested, end-labeled probe was used...
  49. Deuter A, Southee D, Mockett A. Fowlpox virus: pathogenicity and vaccination of day-old chickens via the aerosol route. Res Vet Sci. 1991;50:362-4 pubmed
    Day-old chickens were given a single fowlpox virus vaccination (strain HP201) either via the aerosol or wing-web route...
  50. Wang Y, Chen S, Liu W, Qiu X, Dong L, Peng D, et al. [Induction of potent immune responses by recombinant fowlpox virus with deleted ORF73 or ORF214]. Wei Sheng Wu Xue Bao. 2010;50:512-6 pubmed
    To determine if the fowlpox virus (FPV) ORF73 or ORF214 gene encoding protein has the function of IL-18 binding protein, and to assess the role that ORF73 or ORF214 gene in regulating the immune response.
  51. Liu Q, Zhao J, Su J, Pu J, Zhang G, Liu J. Full genome sequences of two reticuloendotheliosis viruses contaminating commercial vaccines. Avian Dis. 2009;53:341-6 pubmed
    ..The results further indicated that the prototype CSV may be the most-important REV contaminant in the commercial vaccines, and distinct genotypes of REVs may cocirculate in chicken flocks of China at the present time...
  52. Banbura M, Webster R, Cooper M, Doherty P. Size and frequency characteristics of alpha beta and gamma delta T cells in the spleens of normal and cyclophosphamide-suppressed virus-infected chickens. Cell Immunol. 1991;136:242-50 pubmed
    ..However, although the gamma delta T cells increase in size, their frequency in spleen either does not change (CT8+) or is significantly decreased (CT8-)...
  53. Tadese T, Potter A, Fitzgerald S, Reed W. Concurrent infection in chickens with fowlpox virus and infectious laryngotracheitis virus as detected by immunohistochemistry and a multiplex polymerase chain reaction technique. Avian Dis. 2007;51:719-24 pubmed
    A concurrent infection of chickens with infectious laryngotracheitis virus (ILTV), a herpesvirus, and fowlpox virus (FWPV), an avipoxvirus, is described...
  54. Kudo Saito C, Garnett C, Wansley E, Schlom J, Hodge J. Intratumoral delivery of vector mediated IL-2 in combination with vaccine results in enhanced T cell avidity and anti-tumor activity. Cancer Immunol Immunother. 2007;56:1897-910 pubmed
    ..t. boosting with rF-CEA/TRICOM. The addition of intratumoral (i.t.) delivery of IL-2 via a recombinant fowlpox (rF) IL-2 vector greatly enhanced anti-tumor activity of a recombinant vaccine, resulting in complete tumor ..
  55. Nazerian K, Yanagida N. A recombinant fowlpox virus expressing the envelope antigen of subgroup A avian leukosis/sarcoma virus. Avian Dis. 1995;39:514-20 pubmed
    A recombinant fowlpox virus (FPV) was constructed by inserting cloned sequences from Schmidt-Ruppin subgroup A avian sarcoma virus coding for the viral envelope (env) antigen into a nonessential region of FPV DNA downstream from a ..
  56. Lamien C, Meda A, Couacy Hymann E, Ouedraogo A, Nacoulma O. The phytochemical composition and in vitro antiviral activity of decoctions from galls of Guiera senegalensis J.F. Gmel. (Combretaceae) and their relative non-toxicity for chickens. Onderstepoort J Vet Res. 2005;72:111-8 pubmed
    ..senegalensis were screened to determine their phytochemical composition and in vitro antiviral activity against fowlpox virus. In addition, we wanted to investigate the toxic effects, if any, of crude extracts in chickens...
  57. Stratov I, Dale C, Kent S. Phenotypic and kinetic analysis of effective simian-human immunodeficiency virus-specific T cell responses in DNA--and fowlpox virus-vaccinated macaques. Virology. 2005;337:222-34 pubmed
    ..from virulent SHIV challenges in macaques administered priming with DNA vaccines and boosting with recombinant fowlpox viruses expressing shared SIV Gag antigens...
  58. Taylor J, Christensen L, Gettig R, Goebel J, Bouquet J, Mickle T, et al. Efficacy of a recombinant fowl pox-based Newcastle disease virus vaccine candidate against velogenic and respiratory challenge. Avian Dis. 1996;40:173-80 pubmed
  59. Wambura P, Godfrey S. Protective immune response of chickens to oral vaccination with thermostable live Fowlpox virus vaccine (strain TPV-1) coated on oiled rice. Trop Anim Health Prod. 2010;42:451-6 pubmed publisher
    ..In conclusion, the present study has shown that FP vaccine (strain TPV-1) was safe, thermostable, immunogenic and efficacious in vaccinated chickens...
  60. Singh P, Tripathy D. Fowlpox virus infection causes a lymphoproliferative response in chickens. Viral Immunol. 2003;16:223-7 pubmed
    While attenuated fowlpox virus (FPV) strains are widely used for vaccination of chickens and turkeys for prevention of fowlpox, recombinant FPV expressing various foreign genes have been evaluated for their ability to offer protection ..
  61. Fatunmbi O, Reed W. Evaluation of a commercial modified live virus fowl pox vaccine for the control of "variant" fowl poxvirus infections. Avian Dis. 1996;40:582-7 pubmed
    ..The variant isolates tested may be good vaccine candidates to prevent the vaccine breaks currently encountered in previously pox-vaccinated flocks...
  62. Laidlaw S, Robey R, Davies M, Giotis E, Ross C, Buttigieg K, et al. Genetic screen of a mutant poxvirus library identifies an ankyrin repeat protein involved in blocking induction of avian type I interferon. J Virol. 2013;87:5041-52 pubmed publisher
    ..e., mammals, including humans) species, encode no obvious equivalents of any of these proteins. We show that fowlpox virus (FWPV) fails to induce chicken beta IFN (ChIFN2) and is able to block its induction by transfected poly(I·..
  63. Jieyuan J, Spradbrow P. Oral fowlpox vaccination in chickens. Zentralbl Veterinarmed B. 1992;39:388-90 pubmed
    Chickens were given various fowlpox vaccines on food pellets--a commercial vaccine (strain M), and the same strain after a single passage on chorio-allantoic membrane or in chicken embryo fibroblasts...
  64. Boyle D, Heine H. Influence of dose and route of inoculation on responses of chickens to recombinant fowlpox virus vaccines. Vet Microbiol. 1994;41:173-81 pubmed
    The influence of dose and route of inoculation on responses of chickens to vaccination with recombinant fowlpox viruses (rFPVs) expressing an influenza haemagglutinin (HA) (FPV-HA) and the infectious bursal disease virus (IBDV) VP2 ..
  65. York J, Strom A, Connick T, McWaters P, Boyle D, Lowenthal J. In vivo effects of chicken myelomonocytic growth factor: delivery via a viral vector. J Immunol. 1996;156:2991-7 pubmed
    We have constructed a recombinant fowlpox virus (FPV) that expresses chicken myelomonocytic growth factor (cMGF)...
  66. Fatunmbi O, Reed W, Schwartz D, Tripathy D. Dual infection of chickens with pox and infectious laryngotracheitis (ILT) confirmed with specific pox and ILT DNA dot-blot hybridization assays. Avian Dis. 1995;39:925-30 pubmed
  67. Jackwood M. Current and future recombinant viral vaccines for poultry. Adv Vet Med. 1999;41:517-22 pubmed
    ..A vaccine that is novel because it is a recombinant vaccine is not enough. Recombinant vaccines must be safer, or more efficacious, or less expensive to produce in order for them to gain a niche in the marketplace...
  68. Baxi M, Oberoi M. Comparative evaluation of cell culture-adapted and chicken embryo-adapted fowl pox vaccine strains. Avian Dis. 1999;43:16-21 pubmed
    ..The birds vaccinated with VacCE showed only 60% and 20% protection at the corresponding levels, respectively...
  69. Kim T, Schnitzlein W, McAloose D, Pessier A, Tripathy D. Characterization of an avianpox virus isolated from an Andean condor (Vultur gryphus). Vet Microbiol. 2003;96:237-46 pubmed
    ..of specific pathogen free (SPF) chicken embryos was compared biologically, antigenically and genetically with fowlpox virus (FPV), the type species of the genus Avipoxvirus...
  70. Lüschow D, Hoffmann T, Hafez H. [Detection of fowlpox in chickens and turkeys in Germany]. Berl Munch Tierarztl Wochenschr. 2012;125:60-6 pubmed
    ..Diagnostic samples suspected for fowlpox were investigated using the polymerase chain reaction (PCR) in combination with restriction enzyme analysis (REA) ..
  71. Landolt M, Kocan R. Transmission of avian pox from starlings to Rothchild's mynahs. J Wildl Dis. 1976;12:353-6 pubmed
    ..Results indicated the agent was an indigenous starling pox capable of infecting and producing disease in mynah birds. Destruction of the captive starlings and isolation of the remaining mynahs immediately stopped the mortality...
  72. Nakamura K, Waseda K, Yamamoto Y, Yamada M, Nakazawa M, Hata E, et al. Pathology of cutaneous fowlpox with amyloidosis in layer hens inoculated with fowlpox vaccine. Avian Dis. 2006;50:152-6 pubmed
    Cutaneous fowlpox occurring in vaccinated layer hens was investigated pathologically and microbiologically...
  73. Ariyoshi R, Takase K, Matsuura Y, Deguchi K, Ginnaga A, Fujikawa H. Vaccination against Fowlpox virus via drinking water. J Vet Med Sci. 2003;65:1127-30 pubmed
    The oral vaccination against Fowlpox was investigated via drinking water containing the F132-c strain of Fowlpox virus to be effective even though the vaccine virus-titer was 10(4) TCID (50)/dose each time...
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    ..The findings showed that the integrated REV provirus had an effect on the pathogenesis of fowlpox and that the tested vaccine strain is effective against FPV strains carrying REV provirus...