dna virus infections

Summary

Summary: Diseases caused by DNA VIRUSES.

Top Publications

  1. Schock D, Ruthig G, Collins J, Kutz S, Carrière S, Gau R, et al. Amphibian chytrid fungus and ranaviruses in the Northwest Territories, Canada. Dis Aquat Organ. 2010;92:231-40 pubmed publisher
  2. Miller D, Rajeev S, Brookins M, Cook J, Whittington L, Baldwin C. Concurrent infection with ranavirus, Batrachochytrium dendrobatidis, and Aeromonas in a captive anuran colony. J Zoo Wildl Med. 2008;39:445-9 pubmed
    ..Bacterial culture of internal organs yielded Aeromonas hydrophila. This is the first report of concurrent infections in anurans by Ranavirus and Bd and A. hydrophila...
  3. Brink M, Ståhl K, Masembe C, Okurut A, Berg M, Blomström A. First time molecular detection and phylogenetic relationships of torque teno sus virus 1 and 2 in domestic pigs in Uganda: further evidence for a global distribution. Virol J. 2012;9:39 pubmed publisher
    ..Therefore, the aim of this study was to investigate the possible presence of the two viruses in domestic pigs in Uganda, and describe the phylogenetic relationships to those in the rest of the world...
  4. Okamoto H. History of discoveries and pathogenicity of TT viruses. Curr Top Microbiol Immunol. 2009;331:1-20 pubmed
  5. Huang X, Huang Y, Ouyang Z, Cai J, Yan Y, Qin Q. Roles of stress-activated protein kinases in the replication of Singapore grouper iridovirus and regulation of the inflammatory responses in grouper cells. J Gen Virol. 2011;92:1292-301 pubmed publisher
    ..It is proposed that the JNK pathway is important for SGIV replication and modulates the inflammatory responses during virus infection...
  6. Miller D, Gray M, Rajeev S, Schmutzer A, Burton E, Merrill A, et al. Pathologic findings in larval and juvenile anurans inhabiting farm ponds in Tennessee, USA. J Wildl Dis. 2009;45:314-24 pubmed
    ..Protozoans were most common in fecal examination. These data can serve as a baseline to evaluate the presence of clinical disease in larval and juvenile amphibians. ..
  7. Jensen B, Ersbøll A, Ariel E. Susceptibility of pike Esox lucius to a panel of Ranavirus isolates. Dis Aquat Organ. 2009;83:169-79 pubmed publisher
    ..The temperature from where the sample was taken and the number of days after infection were not associated with the probability of a positive virus re-isolation...
  8. Tshering C, Takagi M, Deguchi E. Detection of Torque teno sus virus types 1 and 2 by nested polymerase chain reaction in sera of sows at parturition and of their newborn piglets immediately after birth without suckling colostrum and at 24 hr after suckling colostrum. J Vet Med Sci. 2012;74:315-9 pubmed
    ..These results confirmed the existence of a sow-to-fetus transmission pathway of TTSuV during normal pregnancy and suggested a possibility of sow-to-piglet transmission of TTSuV via colostrum...
  9. Teacher A, Garner T, Nichols R. Evidence for directional selection at a novel major histocompatibility class I marker in wild common frogs (Rana temporaria) exposed to a viral pathogen (Ranavirus). PLoS ONE. 2009;4:e4616 pubmed publisher

More Information

Publications87

  1. Kakkola L, Bond n H, Hedman L, Kivi N, Moisala S, Julin J, et al. Expression of all six human Torque teno virus (TTV) proteins in bacteria and in insect cells, and analysis of their IgG responses. Virology. 2008;382:182-9 pubmed publisher
    ..The genotype-6 sequences remained unaltered for years, suggesting that some mechanisms other than amino acid substitutions play a role in TTV immune evasion...
  2. Ng T, Suedmeyer W, Wheeler E, Gulland F, Breitbart M. Novel anellovirus discovered from a mortality event of captive California sea lions. J Gen Virol. 2009;90:1256-61 pubmed publisher
    ..The higher prevalence of ZcAV and presence of the double-stranded replicative form in the lungs of sea lions from the mortality event suggest that ZcAV was associated with the death of these animals. ..
  3. Raj V, Fournier G, Rakus K, Ronsmans M, Ouyang P, Michel B, et al. Skin mucus of Cyprinus carpio inhibits cyprinid herpesvirus 3 binding to epidermal cells. Vet Res. 2011;42:92 pubmed publisher
    ..The present study demonstrates that skin mucus removal and epidermal lesions enhance CyHV-3 entry in carp. It highlights the role of fish skin mucus as an innate immune protection against viral epidermal entry. ..
  4. Taira O, Ogawa H, Nagao A, Tuchiya K, Nunoya T, Ueda S. Prevalence of swine Torque teno virus genogroups 1 and 2 in Japanese swine with suspected post-weaning multisystemic wasting syndrome and porcine respiratory disease complex. Vet Microbiol. 2009;139:347-50 pubmed publisher
    ..These results suggest that swine TTV may be widespread in post-weaning pigs and could play aetiological roles in pig diseases in Japan. This is the first report on the prevalence of swine TTV in Japan. ..
  5. Sibila M, Martínez Guinó L, Huerta E, Mora M, Grau Roma L, Kekarainen T, et al. Torque teno virus (TTV) infection in sows and suckling piglets. Vet Microbiol. 2009;137:354-8 pubmed publisher
    ..Results of the present study showed that the TTV infection occurs early in the production system and that these viruses may be transmitted from sow-to-piglet but also from piglet-to-piglet in farrowing facilities. ..
  6. Guo C, Wu Y, Yang L, Yang X, He J, Mi S, et al. Infectious spleen and kidney necrosis virus (a fish iridovirus) enters Mandarin fish fry cells via caveola-dependent endocytosis. J Virol. 2012;86:2621-31 pubmed publisher
    ..Thus, our work may help further the understanding of the initial steps of iridovirus infection. ..
  7. Adamek M, Rakus K, Chyb J, Brogden G, Huebner A, Irnazarow I, et al. Interferon type I responses to virus infections in carp cells: In vitro studies on Cyprinid herpesvirus 3 and Rhabdovirus carpio infections. Fish Shellfish Immunol. 2012;33:482-93 pubmed publisher
    ..This would open the opportunity to treat the disease associated with CyHV-3 by an application of poly I:C in certain cases...
  8. Whittington R, Becker J, Dennis M. Iridovirus infections in finfish - critical review with emphasis on ranaviruses. J Fish Dis. 2010;33:95-122 pubmed publisher
  9. Fabian M, Baumer A, Steinhagen D. Do wild fish species contribute to the transmission of koi herpesvirus to carp in hatchery ponds?. J Fish Dis. 2013;36:505-14 pubmed publisher
    ..Furthermore, virus transfer to naive carp was observed after a period of cohabitation. Cyprinid and non-cyprinid wild fish can therefore be considered as an epidemiological risk for pond carp farms. ..
  10. Sharifi Z, Mahmoodian Shooshtari M, Talebian A. The prevalence of SEN virus infection in blood donors in Iran. Arch Iran Med. 2008;11:423-6 pubmed publisher
    ..Our results also showed that the high prevalence of SEN virus in healthy blood donors with no history of blood transfusion may attribute to the transmission modes other than parenteral transmission. ..
  11. Ouyang P, Rakus K, Boutier M, Reschner A, Leroy B, Ronsmans M, et al. The IL-10 homologue encoded by cyprinid herpesvirus 3 is essential neither for viral replication in vitro nor for virulence in vivo. Vet Res. 2013;44:53 pubmed publisher
    ..All together, the results of the present study demonstrate that the IL-10 homologue encoded by CyHV-3 is essential neither for viral replication in vitro nor for virulence in common carp. ..
  12. Glenney G, Julian J, Quartz W. Preliminary amphibian health survey in the Delaware Water Gap National Recreation Area. J Aquat Anim Health. 2010;22:102-14 pubmed publisher
  13. Maggi F, Fabrizio M, Ricci V, Valentina R, Bendinelli M, Mauro B, et al. Changes In CD8+57+ T lymphocyte expansions after autologous hematopoietic stem cell transplantation correlate with changes in torquetenovirus viremia. Transplantation. 2008;85:1867-8 pubmed publisher
  14. Grayfer L, Andino F, Chen G, Chinchar G, Robert J. Immune evasion strategies of ranaviruses and innate immune responses to these emerging pathogens. Viruses. 2012;4:1075-92 pubmed publisher
    ..This review focuses on the recent advances in the understanding of the RV immune evasion strategies with emphasis on the roles of the innate immune system in ranaviral infections. ..
  15. Aramouni M, Segales J, Cortey M, Kekarainen T. Age-related tissue distribution of swine Torque teno sus virus 1 and 2. Vet Microbiol. 2010;146:350-3 pubmed publisher
    ..Both swine TTV species were present in high levels in almost all older animals, while viral negative tissues were only found in 5-week-old and 5-day-old pigs, and foetuses. ..
  16. Huang Y, Ni Y, Dryman B, Meng X. Multiple infection of porcine Torque teno virus in a single pig and characterization of the full-length genomic sequences of four U.S. prototype PTTV strains: implication for genotyping of PTTV. Virology. 2010;396:289-97 pubmed publisher
    ..The identification of novel PTTV strains from pigs in the United States also pave the way for future disease characterization and genotyping of PTTV. ..
  17. Lee S, Sunyoung S, Jung H, Shin J, Lyoo Y. Quantitative detection of porcine Torque teno virus in Porcine circovirus-2-negative and Porcine circovirus-associated disease-affected pigs. J Vet Diagn Invest. 2010;22:261-4 pubmed
    ..Results of this study indicate that there are no statically remarkable differences in TTV viral load between the 2 groups, which indicates that TTV might not be an agent of aggravation in PCVAD...
  18. Whitley D, Sample R, Sinning A, Henegar J, Chinchar V. Antisense approaches for elucidating ranavirus gene function in an infected fish cell line. Dev Comp Immunol. 2011;35:937-48 pubmed publisher
  19. Martínez Guinó L, Kekarainen T, Maldonado J, Aramouni M, Llorens A, Segales J. Torque teno sus virus (TTV) detection in aborted and slaughterhouse collected foetuses. Theriogenology. 2010;74:277-81 pubmed publisher
    ..Results obtained confirm that vertical transmission is an important route of TTVs dissemination. In addition, data obtained suggest that swine TTVs should not be considered as infectious agents responsible for abortion occurrence...
  20. Blomström A, Belak S, Fossum C, Fuxler L, Wallgren P, Berg M. Studies of porcine circovirus type 2, porcine boca-like virus and torque teno virus indicate the presence of multiple viral infections in postweaning multisystemic wasting syndrome pigs. Virus Res. 2010;152:59-64 pubmed publisher
    ..These observations indicate a multiple viral infection in PMWS-affected pigs. It has to be studied further if the clinical manifestation of PMWS might be due to synergistic effects of different viruses acting together...
  21. Driskell E, Miller D, Swist S, Gyimesi Z. PCR detection of ranavirus in adult anurans from the Louisville Zoological Garden. J Zoo Wildl Med. 2009;40:559-63 pubmed
    ..These findings reveal that ranaviral infection in captive adult anurans may occur without clinical signs or consistent histopathologic lesions...
  22. Mazzoni R, de Mesquita A, Fleury L, de Brito W, Nunes I, Robert J, et al. Mass mortality associated with a frog virus 3-like Ranavirus infection in farmed tadpoles Rana catesbeiana from Brazil. Dis Aquat Organ. 2009;86:181-91 pubmed publisher
    ..Additionally, our results suggest that American bullfrogs may have served as a vector of transmission of this virus, which highlights the potential threat of amphibian translocation in the world distribution of pathogens...
  23. Zhu C, Shan T, Cui L, Luo X, Liu Z, Tang S, et al. Molecular detection and sequence analysis of feline Torque teno virus (TTV) in China. Virus Res. 2011;156:13-6 pubmed publisher
    ..5% and 93.3%) identity with the strain of Japan and the strain of France, and SH-F2 shared 94.5% and 92.1% homology with them, respectively. In conclusion, we demonstrated that feline TTV is present in China...
  24. Krakowka S, Ellis J. Evaluation of the effects of porcine genogroup 1 torque teno virus in gnotobiotic swine. Am J Vet Res. 2008;69:1623-9 pubmed publisher
    ..To determine whether porcine genogroup 1 torque teno virus (g1-TTV) can infect and cause disease in gnotobiotic swine...
  25. Gray M, Miller D, Hoverman J. Ecology and pathology of amphibian ranaviruses. Dis Aquat Organ. 2009;87:243-66 pubmed publisher
    ..We also encourage natural resource organizations to establish routine surveillance programs for ranaviruses in wild amphibian populations...
  26. Haislip N, Gray M, Hoverman J, Miller D. Development and disease: how susceptibility to an emerging pathogen changes through anuran development. PLoS ONE. 2011;6:e22307 pubmed publisher
  27. Schloegel L, Daszak P, Cunningham A, Speare R, Hill B. Two amphibian diseases, chytridiomycosis and ranaviral disease, are now globally notifiable to the World Organization for Animal Health (OIE): an assessment. Dis Aquat Organ. 2010;92:101-8 pubmed publisher
    ..This listing made chytridiomycosis and ranaviral disease internationally notifiable diseases and thus subject to OIE standards, which aim to assure the sanitary safety of international trade in live amphibians and their products...
  28. Ariel E, Kielgast J, Svart H, Larsen K, Tapiovaara H, Jensen B, et al. Ranavirus in wild edible frogs Pelophylax kl. esculentus in Denmark. Dis Aquat Organ. 2009;85:7-14 pubmed publisher
    ..The identity of the virus was confirmed by immunofluorescent antibody test. Sequencing of the major capsid protein gene showed the isolate had more than 97.3% nucleotide homology to 6 other ranaviruses...
  29. Cui H, Yan Y, Wei J, Hou Z, Huang Y, Huang X, et al. Cloning, characterization, and expression analysis of orange-spotted grouper (Epinephelus coioides) ILF2 gene (EcILF2). Fish Shellfish Immunol. 2011;30:378-88 pubmed publisher
    ..These results suggest that EcILF2 is potentially involved in grouper immune responses to invasion of bacterial and viral pathogens...
  30. Torrence S, Green D, Benson C, Ip H, Smith L, McMurry S. A new ranavirus isolated from Pseudacris clarkii tadpoles in playa wetlands in the southern High Plains, Texas. J Aquat Anim Health. 2010;22:65-72 pubmed publisher
    ..Thus, the virus may contribute to substantial seasonal population declines and low seasonal recruitment, with negative impacts on populations of breeding adults in successive years...
  31. Johnson A, Pessier A, Wellehan J, Childress A, Norton T, Stedman N, et al. Ranavirus infection of free-ranging and captive box turtles and tortoises in the United States. J Wildl Dis. 2008;44:851-63 pubmed
    ..Amphibians may serve as a reservoir host for susceptible chelonians. This report also demonstrated that significant disease associated with Ranavirus infections are likely more widespread in chelonians than previously suspected...
  32. Michel B, Leroy B, Stalin Raj V, Lieffrig F, Mast J, Wattiez R, et al. The genome of cyprinid herpesvirus 3 encodes 40 proteins incorporated in mature virions. J Gen Virol. 2010;91:452-62 pubmed publisher
    ..The identification of the proteins incorporated into CyHV-3 virions and determination of the viral genes encoding these proteins are key milestones for further fundamental and applied research on this virus...
  33. Allender M, Mitchell M, Torres T, Sekowska J, Driskell E. Pathogenicity of frog virus 3-like virus in red-eared slider turtles (Trachemys scripta elegans) at two environmental temperatures. J Comp Pathol. 2013;149:356-67 pubmed publisher
    ..This study determined that environmental temperature affects the survival and disease progression in ranavirus-infected red-eared slider turtles, which will aid in managing animals in a clinical or free-ranging setting...
  34. Shinmoto H, Taniguchi K, Ikawa T, Kawai K, Oshima S. Phenotypic diversity of infectious red sea bream iridovirus isolates from cultured fish in Japan. Appl Environ Microbiol. 2009;75:3535-41 pubmed publisher
    ..These results revealed that variant characteristics exist in the same phylogenetic location in emergent iridoviruses. We suggest that this strain variation would expand the host range in iridoviral epidemics...
  35. Picco A, Collins J. Amphibian commerce as a likely source of pathogen pollution. Conserv Biol. 2008;22:1582-9 pubmed publisher
    ..The tiger salamander bait trade in the western United States is a useful model for understanding the consequences of the unregulated anthropogenic movement of amphibians and their pathogens through trade...
  36. Schock D, Bollinger T, Collins J. Mortality rates differ among amphibian populations exposed to three strains of a lethal ranavirus. Ecohealth. 2009;6:438-48 pubmed publisher
    ..Our study highlights the need to minimize translocations of amphibian ranaviruses, even among conspecifc host populations, and the importance of considering intraspecific variation in endeavors to manage wildlife diseases...
  37. Gallei A, Pesch S, Esking W, Keller C, Ohlinger V. Porcine Torque teno virus: determination of viral genomic loads by genogroup-specific multiplex rt-PCR, detection of frequent multiple infections with genogroups 1 or 2, and establishment of viral full-length sequences. Vet Microbiol. 2010;143:202-12 pubmed publisher
    ..Moreover, two porcine TTV full-length sequences were established, one for each genogroup...
  38. Cotter J, Storfer A, Page R, Beachy C, Voss S. Transcriptional response of Mexican axolotls to Ambystoma tigrinum virus (ATV) infection. BMC Genomics. 2008;9:493 pubmed publisher
    ..We used a custom microarray gene chip to characterize gene expression responses of axolotls (Ambystoma mexicanum) to an emerging viral pathogen, Ambystoma tigrinum virus (ATV)...
  39. Ellis J, Allan G, Krakowka S. Effect of coinfection with genogroup 1 porcine torque teno virus on porcine circovirus type 2-associated postweaning multisystemic wasting syndrome in gnotobiotic pigs. Am J Vet Res. 2008;69:1608-14 pubmed publisher
    ..To determine whether genogroup 1 porcine torque teno virus (g1-TTV) can potentiate clinical disease associated with porcine circovirus type 2 (PCV2)...
  40. St Amour V, Wong W, Garner T, Lesbarreres D. Anthropogenic influence on prevalence of 2 amphibian pathogens. Emerg Infect Dis. 2008;14:1175-6 pubmed publisher
  41. Miyahira A, Shahangian A, Hwang S, Sun R, Cheng G. TANK-binding kinase-1 plays an important role during in vitro and in vivo type I IFN responses to DNA virus infections. J Immunol. 2009;182:2248-57 pubmed publisher
    ..responses in TBK1(-/-) macrophages infected with an RNA virus, IFN responses were severely abrogated during DNA virus infections in TBK1(-/-) macrophages...
  42. Dropulic L, Cohen J. Update on new antivirals under development for the treatment of double-stranded DNA virus infections. Clin Pharmacol Ther. 2010;88:610-9 pubmed publisher
    ..Additionally, no drugs have been approved to treat several DNA virus infections, including those caused by adenovirus, smallpox, molluscum contagiosum, and BK virus...
  43. Okamoto H. TT viruses in animals. Curr Top Microbiol Immunol. 2009;331:35-52 pubmed
    ..To date, TTVs infecting nonhuman primates and other mammalian species have been under-examined. It is likely that essentially all animals are naturally infected with species-specific TTVs...
  44. Roperto S, Paciello O, Paolini F, Pagnini U, Palma E, Di Palo R, et al. Short communication: Detection of human Torque teno virus in the milk of water buffaloes (Bubalus bubalis). J Dairy Sci. 2009;92:5928-32 pubmed publisher
    ..Finally, the mode of transmission of TTV has not been determined. Contaminated of the food chain with TTV may be a potential risk for human health, representing one of the multiple routes of infection...
  45. Robert J, Gregory Chinchar V. "Ranaviruses: an emerging threat to ectothermic vertebrates" report of the First International Symposium on Ranaviruses, Minneapolis MN July 8, 2011. Dev Comp Immunol. 2012;36:259-61 pubmed publisher
  46. Leu J, Chen L, Lin Y, Kou G, Lo C. Molecular mechanism of the interactions between white spot syndrome virus anti-apoptosis protein AAP-1 (WSSV449) and shrimp effector caspase. Dev Comp Immunol. 2010;34:1068-74 pubmed publisher
    ..Asp233, on the other hand, negatively regulates AAP-1's anti-Pm caspase activity. Lastly, AAP-1 homotypically interacts with each other both in vitro and in insect cells...
  47. Chinchar V, Yu K, Jancovich J. The molecular biology of frog virus 3 and other iridoviruses infecting cold-blooded vertebrates. Viruses. 2011;3:1959-85 pubmed publisher
    ..Collectively, these and future efforts will elucidate molecular events in viral replication, intrinsic and extrinsic factors that contribute to disease outbreaks, and the role of the host immune system in protection from disease...
  48. Rathinam V, Jiang Z, Waggoner S, Sharma S, Cole L, Waggoner L, et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol. 2010;11:395-402 pubmed publisher
    ..Collectively, our observations demonstrate the importance of AIM2 in the sensing of both bacterial and viral pathogens and in triggering innate immunity...
  49. Robert J, George E, De Jesús Andino F, Chen G. Waterborne infectivity of the Ranavirus frog virus 3 in Xenopus laevis. Virology. 2011;417:410-7 pubmed publisher
    ..These data highlight the efficiency of FV3 infectivity by the water route and the ability of FV3 to adapt to its hosts...
  50. Geng Y, Wang K, Zhou Z, Li C, Wang J, He M, et al. First report of a ranavirus associated with morbidity and mortality in farmed Chinese giant salamanders (Andrias davidianus). J Comp Pathol. 2011;145:95-102 pubmed publisher
    ..These salamanders all died within 6-8 days. This is the first report of ranavirus infection associated with mass mortality in Chinese giant salamanders...
  51. Saadi H, Pagnier I, Colson P, Cherif J, Beji M, Boughalmi M, et al. First isolation of Mimivirus in a patient with pneumonia. Clin Infect Dis. 2013;57:e127-34 pubmed publisher
    ..Mimiviruses have been linked to pneumonia, but they have never been isolated from patients. To further understand the pathogenic role of these viruses, we aimed to isolate them from a patient presenting with pneumonia...
  52. Balseiro A, Dalton K, del Cerro A, Marquez I, Cunningham A, Parra F, et al. Pathology, isolation and molecular characterisation of a ranavirus from the common midwife toad Alytes obstetricans on the Iberian Peninsula. Dis Aquat Organ. 2009;84:95-104 pubmed publisher
    ..A rabbit antiserum raised against purified virions was prepared and used to definitively demonstrate systemic distribution of the virus in diseased tadpoles, indicating that the isolated virus was the primary pathogen...
  53. Balseiro A, Dalton K, del Cerro A, Marquez I, Parra F, Prieto J, et al. Outbreak of common midwife toad virus in alpine newts (Mesotriton alpestris cyreni) and common midwife toads (Alytes obstetricans) in northern Spain: a comparative pathological study of an emerging ranavirus. Vet J. 2010;186:256-8 pubmed publisher
    ..This is the first report of ranavirus infection in the alpine newt, the second known species to be affected by CMTV in the past 2 years...
  54. Zhou J, Wei J, Xu D, Cui H, Yan Y, Ou Yang Z, et al. Molecular cloning and characterization of two novel hepcidins from orange-spotted grouper, Epinephelus coioides. Fish Shellfish Immunol. 2011;30:559-68 pubmed publisher
    ..These data should offer important information on the antimicrobial and antiviral roles of EC-hepcidins, and will be help to the better understanding of molecular mechanisms of grouper innate immunity...
  55. Huang Y, Dryman B, Harrall K, Vaughn E, Roof M, Meng X. Development of SYBR green-based real-time PCR and duplex nested PCR assays for quantitation and differential detection of species- or type-specific porcine Torque teno viruses. J Virol Methods. 2010;170:140-6 pubmed publisher
    ..These assays provide rapid and practical tools for molecular diagnosis of species- or type-specific porcine TTV...
  56. Pozzuto T, Mueller B, Meehan B, Ringler S, McIntosh K, Ellis J, et al. In utero transmission of porcine torque teno viruses. Vet Microbiol. 2009;137:375-9 pubmed publisher
    ..These data demonstrate that porcine TTV may be transmitted to piglets by the in utero route and that the incidence of fetal infection is high...
  57. Sibila M, Martínez Guinó L, Huerta E, Llorens A, Mora M, Grau Roma L, et al. Swine torque teno virus (TTV) infection and excretion dynamics in conventional pig farms. Vet Microbiol. 2009;139:213-8 pubmed publisher
    ..Moreover, results indicate that both swine TTV genogroups are able to establish persistent infections in a number of pigs...
  58. Xia L, Cao J, Huang X, Qin Q. Characterization of Singapore grouper iridovirus (SGIV) ORF086R, a putative homolog of ICP18 involved in cell growth control and virus replication. Arch Virol. 2009;154:1409-16 pubmed publisher
    ..Furthermore, overexpression of SGIV ICP18 can promote the growth of grouper embryonic cells (GP) and contribute to SGIV replication. These results should offer important insights into the pathogenesis of ranaviruses...
  59. Greer A, Brunner J, Collins J. Spatial and temporal patterns of Ambystoma tigrinum virus (ATV) prevalence in tiger salamanders Ambystoma tigrinum nebulosum. Dis Aquat Organ. 2009;85:1-6 pubmed publisher
    ..There was no statistically significant spatial pattern in prevalence across the landscape. Our findings highlight the need to explore new hypotheses regarding the population level impact of these pathogens on amphibian communities...
  60. Dong C, Weng S, Luo Y, Huang M, Ai H, Yin Z, et al. A new marine megalocytivirus from spotted knifejaw, Oplegnathus punctatus, and its pathogenicity to freshwater mandarinfish, Siniperca chuatsi. Virus Res. 2010;147:98-106 pubmed publisher
    ..Taken together, the results presented here provide new insight into the pathology of megalocytivirus infection...
  61. Fournier G, Boutier M, Stalin Raj V, Mast J, Parmentier E, Vanderwalle P, et al. Feeding Cyprinus carpio with infectious materials mediates cyprinid herpesvirus 3 entry through infection of pharyngeal periodontal mucosa. Vet Res. 2012;43:6 pubmed publisher
    ..They led to comparable clinical signs and mortality rate. The results of the present study suggest that, based on epidemiological conditions, CyHV-3 can enter carp either by skin or periodontal pharyngeal mucosal infection...
  62. Morales H, Abramowitz L, Gertz J, Sowa J, Vogel A, Robert J. Innate immune responses and permissiveness to ranavirus infection of peritoneal leukocytes in the frog Xenopus laevis. J Virol. 2010;84:4912-22 pubmed publisher
    ..This suggests that although PLs are actively involved in anti-FV3 immune responses, some of these cells can be permissive and harbor quiescent, asymptomatic FV3...
  63. Xu X, Lu Q, Wang R, Lin T, Weng S, Lu L, et al. Identification of the VP92R gene from infectious spleen and kidney necrosis virus. Virus Genes. 2010;41:210-7 pubmed publisher
    ..Therefore, VP92R may have specific functions during ISKNV pathogenesis and could be a subject for studying the differences between megalocytiviruses...
  64. Gobbo F, Cappellozza E, Pastore M, Bovo G. Susceptibility of black bullhead Ameiurus melas to a panel of ranavirus isolates. Dis Aquat Organ. 2010;90:167-74 pubmed publisher
    ..No significant mortality was recorded in fish challenged with European sheatfish virus (ESV), Frog virus 3 (FV3), Rana esculenta virus-like (REV-like), Bohle iridovirus (BIV) or short-finned eel virus (SERV)...
  65. Takacs M, Dencs A, Csiszár C, Hettmann A, Rusvai E, Szomor K, et al. First description of swine Torque teno virus (TTV) and detection of a new genogroup in Hungary: short communication. Acta Vet Hung. 2008;56:547-53 pubmed publisher
    ..However, the sequences derived from one liver were remarkably different from all other known genogroups and seemed to represent a new genogroup...
  66. Shi C, Jia K, Yang B, Huang J. Complete genome sequence of a Megalocytivirus (family Iridoviridae) associated with turbot mortality in China. Virol J. 2010;7:159 pubmed publisher
    ..We here sequenced and analyzed the complete genome of TRBIV, which was identified in Shandong province, China...
  67. Mei M, Zhu L, Wang Y, Xu Z, Zhao L, Peng X, et al. Histopathological investigation in porcine infected with torque teno sus virus type 2 by inoculation. Virol J. 2011;8:545 pubmed publisher
    ..However, there exists no information about histopathological lesions caused by infection with porcine TTSuV2...
  68. Pinho Nascimento C, Leite J, Niel C, Diniz Mendes L. Torque teno virus in fecal samples of patients with gastroenteritis: prevalence, genogroups distribution, and viral load. J Med Virol. 2011;83:1107-11 pubmed publisher
    ..However, only moderate variations of viral load were noted depending on genogroup and number of coinfecting TTV genogroups. These results show a high prevalence and a diversity of TTV isolates in feces...
  69. Mavian C, López Bueno A, Balseiro A, Casais R, Alcami A, Alejo A. The genome sequence of the emerging common midwife toad virus identifies an evolutionary intermediate within ranaviruses. J Virol. 2012;86:3617-25 pubmed publisher
    ..This work sheds light on the phylogenetic relationships within this complex group of emerging, disease-causing viruses...
  70. Huang Y, Harrall K, Dryman B, Beach N, Kenney S, Opriessnig T, et al. Expression of the putative ORF1 capsid protein of Torque teno sus virus 2 (TTSuV2) and development of Western blot and ELISA serodiagnostic assays: correlation between TTSuV2 viral load and IgG antibody level in pigs. Virus Res. 2011;158:79-88 pubmed publisher
    ..01). This is the first study to establish essential serodiagnostic tools for investigation of TTSuV seroprevalence and infection dynamics, which will help elucidate the potential pathogenicity of TTSuV infection in pigs...
  71. Lilius E, Nuutila J. Bacterial infections, DNA virus infections, and RNA virus infections manifest differently in neutrophil receptor expression. ScientificWorldJournal. 2012;2012:527347 pubmed publisher
  72. Maggi F, Bendinelli M. Human anelloviruses and the central nervous system. Rev Med Virol. 2010;20:392-407 pubmed publisher
    ..In this review, we briefly outline the general properties of anelloviruses, examine what is currently known about the interactions they establish with the central nervous system (CNS), and discuss the possible pathological consequences...
  73. Fu X, Li N, Liu L, Lin Q, Wang F, Lai Y, et al. Genotype and host range analysis of infectious spleen and kidney necrosis virus (ISKNV). Virus Genes. 2011;42:97-109 pubmed publisher
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    ..To commence proper antiviral treatment, timely knowledge of whether the infection is caused by DNA or RNA virus would be beneficial for the clinician...
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    ..These results have important implications for an understanding of the diversity of anelloviruses as well as for the classification and vaccine development of TTSuVs...
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    ..This is a first demonstration of ERK-mediated nonapoptotic cell death induced by a DNA virus. These findings contribute to understanding the mechanisms of iridovirus pathogenesis...