colonic pouches

Summary

Summary: Sacs or reservoirs created to function in place of the COLON and/or RECTUM in patients who have undergone restorative proctocolectomy (PROCTOCOLECTOMY, RESTORATIVE).

Top Publications

  1. Krausz M, Duek S. Restorative proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis and familial adenomatous polyposis: twenty years follow-up in 174 patients. Isr Med Assoc J. 2005;7:23-7 pubmed
    ..Restorative proctocolectomy with ileal pouch-anal anastomosis has become the surgical procedure of choice for patients with ulcerative colitis and familial adenomatous polyposis...
  2. Schaus B, Fazio V, Remzi F, Bennett A, Lashner B, Shen B. Clinical features of ileal pouch polyps in patients with underlying ulcerative colitis. Dis Colon Rectum. 2007;50:832-8 pubmed
    ..Although the majority of polyps were inflammatory type, polyps in two patients were dysplastic or malignant. Endoscopic polypectomy with concomitant medical therapy seemed to improve patients' symptom scores. ..
  3. Kariv R, Remzi F, Lian L, Bennett A, Kiran R, Kariv Y, et al. Preoperative colorectal neoplasia increases risk for pouch neoplasia in patients with restorative proctocolectomy. Gastroenterology. 2010;139:806-12, 812.e1-2 pubmed publisher
    ..We characterized features, risk factors, and outcomes of pouch neoplasia in patients with inflammatory bowel disease in a historical cohort study...
  4. Zárate C A, Zúñiga D A, Pinedo M G, López K F, Molina P M, Viviani G P. [Ileal pouch-anal anastomosis for ulcerative colitis: complications and long term functional results]. Rev Med Chil. 2008;136:467-74 pubmed publisher
    ..The ileo anal-pouch-anastomosis (IPAA) is the treatment of choice for patients with ulcerative colitis (UC)...
  5. Yamaguchi T, Yamamoto S, Fujita S, Akasu T, Moriya Y. Long-term outcome of metachronous rectal cancer following ileorectal anastomosis for familial adenomatous polyposis. J Gastrointest Surg. 2010;14:500-5 pubmed publisher
    ..Total colectomy with ileorectal anastomosis (IRA) for familial adenomatous polyposis (FAP) carries a potential risk of metachronous cancer in the residual rectum. This study evaluated the risk of cancer development in the residual rectum...
  6. Indar A, Efron J, Young Fadok T. Laparoscopic ileal pouch-anal anastomosis reduces abdominal and pelvic adhesions. Surg Endosc. 2009;23:174-7 pubmed publisher
    ..Adhesions are responsible for more than 75% of small bowel obstruction cases. This study aimed to evaluate adhesions to the anterior abdominal wall and adnexal organs after laparoscopic ileal-pouch anal anastomosis (IPAA)...
  7. Fichera A, Silvestri M, Hurst R, Rubin M, Michelassi F. Laparoscopic restorative proctocolectomy with ileal pouch anal anastomosis: a comparative observational study on long-term functional results. J Gastrointest Surg. 2009;13:526-32 pubmed publisher
    ..Long-term results after laparoscopic ileal pouch anal anastomosis (IPAA) have not been thoroughly evaluated. Our study prospectively compares short- and long-term outcomes of laparoscopic and open IPAA...
  8. Coffey J, Rowan F, Burke J, Dochery N, Dochery N, Kirwan W, et al. Pathogenesis of and unifying hypothesis for idiopathic pouchitis. Am J Gastroenterol. 2009;104:1013-23 pubmed publisher
    ..The implications for the management of both pouchitis and ulcerative colitis are discussed...
  9. Remzi F, Fazio V, Kirat H, Wu J, Lavery I, Kiran R. Repeat pouch surgery by the abdominal approach safely salvages failed ileal pelvic pouch. Dis Colon Rectum. 2009;52:198-204 pubmed publisher
    ..This study evaluated outcomes of patients with abdominal salvage operations for failed ileal pouch-anal anastomosis...

More Information

Publications74

  1. Leowardi C, Hinz U, Tariverdian M, Kienle P, Herfarth C, Ulrich A, et al. Long-term outcome 10 years or more after restorative proctocolectomy and ileal pouch-anal anastomosis in patients with ulcerative colitis. Langenbecks Arch Surg. 2010;395:49-56 pubmed publisher
  2. M Koma A, Moses H, Adunyah S. Inflammatory bowel disease-associated colorectal cancer: proctocolectomy and mucosectomy do not necessarily eliminate pouch-related cancer incidences. Int J Colorectal Dis. 2011;26:533-52 pubmed publisher
    ..We review IBD-associated CRC and pouch-related neoplasia prevalence, adverse events, risk factors, and surveillances...
  3. Leal R, Coy C, Ayrizono M, Fagundes J, Milanski M, Saad M, et al. Differential expression of pro-inflammatory cytokines and a pro-apoptotic protein in pelvic ileal pouches for ulcerative colitis and familial adenomatous polyposis. Tech Coloproctol. 2008;12:33-8 pubmed publisher
    ..However, its frequency is quite rare in patients with familial adenomatous polyposis (FAP). We evaluated the inflammatory and pro-apoptotic activity in endoscopically normal mucosa of the ileal pouch in patients with UC and FAP...
  4. Leal R, Ayrizono M, Coy C, Fagundes J, Góes J. [Short-term and long-term postoperative complications after ileal pouch-anal anastomosis in familial adenomatous polyposis]. Arq Gastroenterol. 2008;45:106-10 pubmed
    ..Restorative proctocolectomy is the procedure of choice to treat familial adenomatous polyposis, however it can be associated to short-term and long-term postoperative complications...
  5. Loftus E, Friedman H, Delgado D, Sandborn W. Colectomy subtypes, follow-up surgical procedures, postsurgical complications, and medical charges among ulcerative colitis patients with private health insurance in the United States. Inflamm Bowel Dis. 2009;15:566-75 pubmed publisher
  6. Banasiewicz T, Marciniak R, Kaczmarek E, Meissner W, Krokowicz P, Paszkowski J, et al. The diameter of the ileal J-pouch-anal anastomosis as an important risk factor of pouchitis - clinical observations. Med Sci Monit. 2011;17:CR91-6 pubmed
    ..Patients' quality of life after restorative proctocolectomy depends on the potential complications. Stricture of the ileal pouch-anal anastomosis is one of the complications following restorative proctocolectomy...
  7. Wuthrich P, Gervaz P, Ambrosetti P, Soravia C, Morel P. Functional outcome and quality of life after restorative proctocolectomy and ileo-anal pouch anastomosis. Swiss Med Wkly. 2009;139:193-7 pubmed publisher
    ..The aim of our study was to evaluate the functional results of this procedure and to assess its impact upon patient quality of life (QoL)...
  8. Tajika M, Nakamura T, Nakahara O, Kawai H, Komori K, Hirai T, et al. Prevalence of adenomas and carcinomas in the ileal pouch after proctocolectomy in patients with familial adenomatous polyposis. J Gastrointest Surg. 2009;13:1266-73 pubmed publisher
    ..Our aim was to evaluate the prevalence, nature, and etiology of ileal pouch and nonpouch adenomas and carcinoma in patients with FAP...
  9. Atila K, Terzi C, Canda A, Akhisaroglu S, Avci H, Sarioglu S, et al. Partially hydrolyzed guar gum attenuates the severity of pouchitis in a rat model of ileal J pouch-anal anastomosis. Dig Dis Sci. 2009;54:522-9 pubmed publisher
    ..This study demonstrated that rectal administration of PHGG attenuates the severity of pouchitis in a rat model. In conclusion, PHGG may be an additional therapeutic strategy for the treatment of pouchitis...
  10. Schmitz Winnenthal F, Kadmon M, Schwab E, Galindo L, Blauer K, Niethammer A, et al. Functional outcome after restorative proctocolectomy in pigs: comparing a novel transverse ileal pouch to the J-pouch and straight ileoanal anastomosis. J Gastrointest Surg. 2009;13:261-8 pubmed publisher
  11. Friederich P, de Jong A, Mathus Vliegen L, Dekker E, Krieken H, Dees J, et al. Risk of developing adenomas and carcinomas in the ileal pouch in patients with familial adenomatous polyposis. Clin Gastroenterol Hepatol. 2008;6:1237-42 pubmed publisher
    ..The aim of this study was to evaluate the long-term risk of developing adenomas and carcinomas in the pouch in a large cohort of Dutch FAP patients...
  12. Pinto R, Canedo J, Murad Regadas S, Regadas S, Weiss E, Wexner S. Ileal pouch-anal anastomosis in elderly patients: is there a difference in morbidity compared with younger patients?. Colorectal Dis. 2011;13:177-83 pubmed publisher
    ..The aim of this study was to review the recent results of ileal pouch-anal anastomosis (IPAA) in elderly patients compared with younger patients...
  13. Navaneethan U, Shen B. Laboratory tests for patients with ileal pouch-anal anastomosis: clinical utility in predicting, diagnosing, and monitoring pouch disorders. Am J Gastroenterol. 2009;104:2606-15 pubmed publisher
  14. Norwood M, Mann C, West K, Miller A, Hemingway D. Restorative proctocolectomy. Does ethnicity affect outcome?. Colorectal Dis. 2009;11:972-5 pubmed publisher
    ..We review outcome of pouch surgery from a single centre, comparing non-South Asian and South Asian Caucasian populations...
  15. Wu H, Shen B. Pouchitis: lessons for inflammatory bowel disease. Curr Opin Gastroenterol. 2009;25:314-22 pubmed publisher
    ..e., pouchitis) that mimics IBD...
  16. Pardi D, Shen B. Endoscopy in the management of patients after ileal pouch surgery for ulcerative colitis. Endoscopy. 2008;40:529-33 pubmed publisher
    ..This paper will review the differential diagnosis of pouchitis and the role of endoscopy in the diagnosis and management of disorders of the ileal pouch. ..
  17. Hallberg H, Ståhlberg D, Akerlund J. Ileal pouch-anal anastomosis (IPAA): functional outcome after postoperative pelvic sepsis. A prospective study of 100 patients. Int J Colorectal Dis. 2005;20:529-33 pubmed
    ..There was one failure in the control group. In this study, no evidence was found that suggested pelvic sepsis postoperatively impairs functional outcome after IPAA at long-term follow-up. ..
  18. Friederich P, Berkhout M, Roelofs H, van Goor H, van Krieken J, Peters W, et al. Decreased levels of mucosal detoxification enzymes in the pouch of patients with familial adenomatous polyposis. Br J Surg. 2006;93:1108-14 pubmed
    ..After IPAA, GST detoxification activity in the pouch is significantly lower than that in the afferent ileal loop, which may promote tumorigenesis. ..
  19. Remzi F, Fazio V, Gorgun E, Ooi B, Hammel J, Preen M, et al. The outcome after restorative proctocolectomy with or without defunctioning ileostomy. Dis Colon Rectum. 2006;49:470-7 pubmed
    ..Quality of life and functional results are similar to those who undergo ileal pouch-anal anastomosis with diversion, provided that certain selection factors are considered. ..
  20. Vrouenraets B, Van Duijvendijk P, Bemelman W, Offerhaus G, Slors J. Adenocarcinoma in the anal canal after ileal pouch-anal anastomosis for familial adenomatous polyposis using a double-stapled technique: report of two cases. Dis Colon Rectum. 2004;47:530-4 pubmed
    ..Endoscopic biopsies ten years postoperatively revealed adenocarcinoma T4N0M0. The patient underwent an abdominoperineal resection with partial resection of the prostate, and a permanent ileostomy was constructed. ..
  21. Schluender S, Mei L, Yang H, Fleshner P. Can a meta-analysis answer the question: is mucosectomy and handsewn or double-stapled anastomosis better in ileal pouch-anal anastomosis?. Am Surg. 2006;72:912-6 pubmed
    ..This meta-analysis demonstrates that DS-IPAA offers no advantage in functional or manometric outcome when compared with HS-IPAA...
  22. Nilubol N, Scherl E, Bub D, Gorfine S, Marion J, Harris M, et al. Mucosal dysplasia in ileal pelvic pouches after restorative proctocolectomy. Dis Colon Rectum. 2007;50:825-31 pubmed
    ..Ileal-pouch mucosal dysplasia is uncommon, occurring in only 1 of 138 patients. Villous atrophy and colonic metaplasia were not observed in this series. Routine pouch surveillance with biopsies may not be warranted. ..
  23. Ferrante M, Declerck S, De Hertogh G, Van Assche G, Geboes K, Rutgeerts P, et al. Outcome after proctocolectomy with ileal pouch-anal anastomosis for ulcerative colitis. Inflamm Bowel Dis. 2008;14:20-8 pubmed
    ..004). Pouch failure occurred in 5% of patients. Although proctocolectomy with IPAA surgery has a good functional outcome, postoperative complications, especially pouchitis, remain considerable in patients with UC. ..
  24. Fowler A, Turner B, Thomson W. A study of the complications and pelvic visceral function after restorative proctocolectomy and W pouch construction. Colorectal Dis. 2003;5:342-6 pubmed
    ..Pouch frequency is less if wind can be passed separately; otherwise functional outcome seems determined by other, non-technical, factors. ..
  25. Yamamoto T, Umegae S, Kitagawa T, Matsumoto K. The impact of the fecal stream and stasis on immunologic reactions in ileal pouch after restorative proctocolectomy for ulcerative colitis: a prospective, pilot study. Am J Gastroenterol. 2005;100:2248-53 pubmed
    ..The immunological reactions in the pouch occurred soon after ileostomy closure, and continued for at least 1 yr. The fecal stream and stasis play an important part in the pathogenesis of immunological reactions in the ileal pouch. ..
  26. Teixeira M, Ponte A, Sousa M, Almeida M, Silva Filho E, Calache J, et al. Short- and long-term outcomes of ileal pouch-anal anastomosis for ulcerative colitis. Rev Hosp Clin Fac Med Sao Paulo. 2003;58:193-8 pubmed
    ..There was no correlation between pouchitis and severe disease, operation with or without ileostomy, or early postoperative complications. The incidence of pouchitis was directly proportional to duration of time of follow-up. ..
  27. Yu E, Shao Z, Shen B. Pouchitis. World J Gastroenterol. 2007;13:5598-604 pubmed
    ..The majority of patients respond favorably to antibiotic therapy. However, management of chronic antibiotic-refractory pouchitis remains a challenge...
  28. Kiran R, Remzi F, Fazio V, Lavery I, Church J, Strong S, et al. Complications and functional results after ileoanal pouch formation in obese patients. J Gastrointest Surg. 2008;12:668-74 pubmed publisher
    ..We compare outcomes for patients with a body mass index (BMI) > or =30 undergoing IPAA when compared with those for patients with BMI <30...
  29. Cordero Fernández C, Pizarro Moreno A, Garzón Benavides M, García Lozano R, Belda Laguna O, Sobrino S, et al. [Follow-up after surgical treatment of patients with familial adenomatous polyposis: results in a southern Spanish population]. Rev Esp Enferm Dig. 2007;99:440-5 pubmed
  30. Hurlstone D, Saunders B, Church J. Endoscopic surveillance of the ileoanal pouch following restorative proctocolectomy for familial adenomatous polyposis. Endoscopy. 2008;40:437-42 pubmed publisher
    ..In the future, novel adjunctive endoscopic technologies such as magnification endoscopy and confocal endomicroscopy may improve our diagnostic and therapeutic management of this group...
  31. Herline A, Meisinger L, Rusin L, Roberts P, Murray J, Coller J, et al. Is routine pouch surveillance for dysplasia indicated for ileoanal pouches?. Dis Colon Rectum. 2003;46:156-9 pubmed
    ..This study was designed to evaluate our institutional incidence of dysplasia in ileoanal pouch during long-term follow-up...
  32. Walkowiak J, Banasiewicz T, Krokowicz P, Hansdorfer Korzon R, Drews M, Herzig K. Fecal pyruvate kinase (M2-PK): a new predictor for inflammation and severity of pouchitis. Scand J Gastroenterol. 2005;40:1493-4 pubmed
  33. Chapman J, Larson D, Wolff B, Dozois E, Cima R, Pemberton J, et al. Ileal pouch-anal anastomosis: does age at the time of surgery affect outcome?. Arch Surg. 2005;140:534-9; discussion 539-40 pubmed
    ..Our aim was to update our understanding on how the age of the patient at the time of surgery influences functional outcome and quality of life after IPAA...
  34. Gualdrini U, Coraglio M, Filippa L, Masciangioli G, Gutierrez A, Lumi C, et al. [Long term functional outcomes after ileoanal pouch in patients with and without postoperative complications]. Acta Gastroenterol Latinoam. 2007;37:143-9 pubmed
    ..the proctocolectomy with ilealpouch (IP) has become the gold standard for surgical treatment for ulcerative colitis (UC). The postoperative complications are frequent but the definitive outcome is acceptable...
  35. Swenson B, Hollenbeak C, Poritz L, Koltun W. Modified two-stage ileal pouch-anal anastomosis: equivalent outcomes with less resource utilization. Dis Colon Rectum. 2005;48:256-61 pubmed
    ..The present study sought to evaluate the safety, results, cost, and length of hospital stay using this modified approach compared to that of the traditional three-stage ileal pouch-anal anastomosis...
  36. Laake K, Bjørneklett A, Aamodt G, Aabakken L, Jacobsen M, Bakka A, et al. Outcome of four weeks' intervention with probiotics on symptoms and endoscopic appearance after surgical reconstruction with a J-configurated ileal-pouch-anal-anastomosis in ulcerative colitis. Scand J Gastroenterol. 2005;40:43-51 pubmed
  37. Campos F, Habr Gama A, Kiss D, da Silva E, Rawet V, Imperiale A, et al. Adenocarcinoma after ileoanal anastomosis for familial adenomatous polyposis: review of risk factors and current surveillance apropos of a case. J Gastrointest Surg. 2005;9:695-702 pubmed
    ..Although the long-term risk of malignancy is not known, lifelong follow-up seems to be necessary after restorative proctocolectomy. Current recommendations for pouch surveillance are presented...
  38. Sagap I, Remzi F, Hammel J, Fazio V. Factors associated with failure in managing pelvic sepsis after ileal pouch-anal anastomosis (IPAA)--a multivariate analysis. Surgery. 2006;140:691-703; discussion 703-4 pubmed
    ..Pelvic sepsis is known to cause a detrimental outcome after ileal pouch-anal anastomosis (IPAA). The aim of this study was to examine potential factors associated with failure in managing pelvic sepsis after IPAA...
  39. Cherki S, Glehen O, Moutardier V, Francois Y, Gilly F, Vignal J. Pouch adenocarcinoma after restorative proctocolectomy for familial adenomatous polyposis. Colorectal Dis. 2003;5:592-4 pubmed
  40. Tilney H, Lovegrove R, Heriot A, Purkayastha S, Constantinides V, Nicholls R, et al. Comparison of short-term outcomes of laparoscopic vs open approaches to ileal pouch surgery. Int J Colorectal Dis. 2007;22:531-42 pubmed
    ..The present meta-analysis compared short-term outcomes between patients undergoing laparoscopic and open restorative proctocolectomy...
  41. Shen B, Fazio V, Remzi F, Delaney C, Bennett A, Achkar J, et al. Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses. Am J Gastroenterol. 2005;100:93-101 pubmed
    ..Symptomatology, endoscopy, histology, and the Cleveland Global QOL and the Irritable Bowel Syndrome-QOL scores were compared among the groups...
  42. Dinnewitzer A, Wexner S, Baig M, Oberwalder M, Pishori T, Weiss E, et al. Timing of restorative proctectomy following subtotal colectomy in patients with inflammatory bowel disease. Colorectal Dis. 2006;8:278-82 pubmed
    ..The aim of this study was to determine the impact of timing of RPC in patients who have undergone subtotal colectomy and end ileostomy for inflammatory bowel disease (IBD)...
  43. Hoda K, Collins J, Knigge K, Deveney K. Predictors of pouchitis after ileal pouch-anal anastomosis: a retrospective review. Dis Colon Rectum. 2008;51:554-60 pubmed publisher
    ..The primary end point of this study was to determine the risk factors that predict chronic pouchitis in those patients having ileal pouch-anal anastomosis...
  44. Aziz O, Athanasiou T, Fazio V, Nicholls R, Darzi A, Church J, et al. Meta-analysis of observational studies of ileorectal versus ileal pouch-anal anastomosis for familial adenomatous polyposis. Br J Surg. 2006;93:407-17 pubmed
    ..Colectomy with ileorectal anastomosis and proctocolectomy with ileal pouch-anal anastomosis both offer this, but there is no clear consensus about which is better...
  45. Koh P, Tang C, Eu K, Samuel M, Chan E. A systematic review of the function and complications of colonic pouches. Int J Colorectal Dis. 2007;22:543-8 pubmed
    ..This is a meta-analysis of randomized, controlled trials to compare the function and complications of a straight coloanal anastomosis to a colonic J-pouch after rectal excision at 1 year postoperatively...
  46. Hueting W, Buskens E, van der Tweel I, Gooszen H, van Laarhoven C. Results and complications after ileal pouch anal anastomosis: a meta-analysis of 43 observational studies comprising 9,317 patients. Dig Surg. 2005;22:69-79 pubmed
  47. Carmon E, Keidar A, Ravid A, Goldman G, Rabau M. The correlation between quality of life and functional outcome in ulcerative colitis patients after proctocolectomy ileal pouch anal anastomosis. Colorectal Dis. 2003;5:228-32 pubmed
  48. Lovegrove R, Constantinides V, Heriot A, Athanasiou T, Darzi A, Remzi F, et al. A comparison of hand-sewn versus stapled ileal pouch anal anastomosis (IPAA) following proctocolectomy: a meta-analysis of 4183 patients. Ann Surg. 2006;244:18-26 pubmed
    ..Using meta-analytical techniques, the study compared postoperative adverse events and functional outcomes of stapled versus hand-sewn ileal pouch-anal anastomosis (IPAA) following restorative proctocolectomy...
  49. Hassan I, Chua H, Wolff B, Donnelly S, Dozois R, Larson D, et al. Quality of life after ileal pouch-anal anastomosis and ileorectal anastomosis in patients with familial adenomatous polyposis. Dis Colon Rectum. 2005;48:2032-7 pubmed
    ..We therefore sought to ascertain not only the surgical results but also the perceptions of patients about their outcomes...
  50. Friederich P, van Heumen B, Nagtegaal I, Berkhout M, van Krieken J, Peters W, et al. Increased epithelial cell proliferation in the ileal pouch mucosa of patients with familial adenomatous polyposis. Virchows Arch. 2007;451:659-67 pubmed
  51. Groves C, Beveridge l, Swain D, Saunders B, Talbot I, Nicholls R, et al. Prevalence and morphology of pouch and ileal adenomas in familial adenomatous polyposis. Dis Colon Rectum. 2005;48:816-23 pubmed
    ..Our aim was to evaluate prospectively the prevalence, nature, and etiology of pouch ileal adenomas with that of nonpouch ileal adenomas in familial adenomatous polyposis...
  52. Ooi B, Remzi F, Gramlich T, Church J, Preen M, Fazio V. Anal transitional zone cancer after restorative proctocolectomy and ileoanal anastomosis in familial adenomatous polyposis: report of two cases. Dis Colon Rectum. 2003;46:1418-23; discussion 1422-3 pubmed
    ..We report two cases of this cancer from the anal transitional zone in patients with familial adenomatous polyposis, with a review of the literature...
  53. Kadmon M. [Preventive surgery for familial adenomatous polyposis coli]. Chirurg. 2005;76:1125-34 pubmed
    ..The development of reliable guidelines for attenuated FAP variants requires further evidence from clinical studies on surgical strategy and the advantages of prophylactic surgery over regular endoscopic screening with removal of polyps...
  54. Hata K, Watanabe T, Shinozaki M, Nagawa H. Patients with extraintestinal manifestations have a higher risk of developing pouchitis in ulcerative colitis: multivariate analysis. Scand J Gastroenterol. 2003;38:1055-8 pubmed
    ..The aim of our study is to clarify the cumulative risk and risk factors for developing pouchitis in Japanese patients with UC undergoing IPAA...
  55. Remzi F, Fazio V, Delaney C, Preen M, Ormsby A, Bast J, et al. Dysplasia of the anal transitional zone after ileal pouch-anal anastomosis: results of prospective evaluation after a minimum of ten years. Dis Colon Rectum. 2003;46:6-13 pubmed
  56. Michelassi F, Lee J, Rubin M, Fichera A, Kasza K, Karrison T, et al. Long-term functional results after ileal pouch anal restorative proctocolectomy for ulcerative colitis: a prospective observational study. Ann Surg. 2003;238:433-41; discussion 442-5 pubmed
    ..To document functional results in patients treated with an ileal pouch anal anastomosis (IPAA)...
  57. Kuisma J, Mentula S, Luukkonen P, Jarvinen H, Kahri A, Farkkila M. Factors associated with ileal mucosal morphology and inflammation in patients with ileal pouch-anal anastomosis for ulcerative colitis. Dis Colon Rectum. 2003;46:1476-83 pubmed
  58. Berndtsson I, Lindholm E, Oresland T, Borjesson L. Long-term outcome after ileal pouch-anal anastomosis: function and health-related quality of life. Dis Colon Rectum. 2007;50:1545-52 pubmed
    ..This study was designed to investigate long-term pouch function and health-related quality of life in a single, large cohort of patients with ileal pouch-anal anastomosis for ulcerative colitis...
  59. Lin J, Song Z, Xu J. [The prognosis of the total proctocolectomy and ileal-pouch anal anastomosis]. Zhonghua Wai Ke Za Zhi. 2004;42:861-3 pubmed
    ..To evaluate the prognosis of the total proctocolectomy and ileal-pouch anal anastomosis (IPAA) for ulcerative colitis (UC) and familial adenomatous polyposis (FAP)...
  60. Moussata D, Nancey S, Lapalus M, Prost B, Chavaillon A, Bernard G, et al. Frequency and severity of ileal adenomas in familial adenomatous polyposis after colectomy. Endoscopy. 2008;40:120-5 pubmed
    ..Our aim was to evaluate retrospectively the frequency of and time interval to adenoma development in the ileal mucosa of patients with both types of surgery...
  61. Walker M, Radley S. Adenocarcinoma in an ileoanal pouch formed for ulcerative colitis in a patient with primary sclerosing cholangitis and a liver transplant: report of a case and review of the literature. Dis Colon Rectum. 2006;49:909-12 pubmed
    ..There is also the need for longer-term follow-up data to determine the risk of this rare and potentially devastating complication of restorative proctocolectomy...
  62. Ho K, Chang C, Baig M, Borjesson L, Nogueras J, Efron J, et al. Ileal pouch anal anastomosis for ulcerative colitis is feasible for septuagenarians. Colorectal Dis. 2006;8:235-8 pubmed
    ..Results in these patients were compared to the results in a group of patients aged less than 70 years who had IPAA...
  63. Knupper N, Straub E, Terpe H, Vestweber K. Adenocarcinoma of the ileoanal pouch for ulcerative colitis--a complication of severe chronic atrophic pouchitis?. Int J Colorectal Dis. 2006;21:478-82 pubmed
    ..We report a case of an adenocarcinoma arising in all probability from the ileal pouch after malignant transformation of the ileal pouch mucosa based on a chronic atrophic pouchitis...
  64. Holubar S, Hyman N. Continence alterations after ileal pouch-anal anastomosis do not diminish quality of life. Dis Colon Rectum. 2003;46:1489-91 pubmed
  65. Fruin A, El Zammer O, Stucchi A, O Brien M, Becker J. Colonic metaplasia in the ileal pouch is associated with inflammation and is not the result of long-term adaptation. J Gastrointest Surg. 2003;7:246-53; discussion 253-4 pubmed
    ..These morphologic changes in the ileal pouch are found primarily in the setting of inflammation, and likely represent a reparative response...