serous membrane


Summary: A thin lining of closed cavities of the body, consisting of a single layer of squamous epithelial cells (MESOTHELIUM) resting on a thin layer of CONNECTIVE TISSUE, and covered with secreted clear fluid from blood and lymph vessels. Major serous membranes in the body include PERICARDIUM; PERITONEUM; and PLEURA.

Top Publications

  1. Cecchettini A, Falleni A, Gremigni V, Locci M, Masetti M, Bradley J, et al. Yolk utilization in stick insects entails the release of vitellin polypeptides into the perivitelline fluid. Eur J Cell Biol. 2001;80:458-65 pubmed
  2. Schmidt Ott U. Insect serosa: a head line in comparative developmental genetics. Curr Biol. 2005;15:R245-7 pubmed
    ..The results shed light on the functional evolution of bicoid, a zen paralogue of higher flies, which determines anterior body parts...
  3. van der Zee M, Berns N, Roth S. Distinct functions of the Tribolium zerknüllt genes in serosa specification and dorsal closure. Curr Biol. 2005;15:624-36 pubmed
    ..In Drosophila, amnioserosa formation depends on the dorsoventral patterning gene zerknüllt (zen), a derived Hox3 gene...
  4. Panfilio K, Liu P, Akam M, Kaufman T. Oncopeltus fasciatus zen is essential for serosal tissue function in katatrepsis. Dev Biol. 2006;292:226-43 pubmed
    ..Of-zen is also expressed in the blastoderm, although this early expression shows no apparent correlation with defects seen by RNAi knockdown...
  5. Grimaldi A, Caccia S, Congiu T, Ferrarese R, Tettamanti G, Rivas Pena M, et al. Structure and function of the extraembryonic membrane persisting around the larvae of the parasitoid Toxoneuron nigriceps. J Insect Physiol. 2006;52:870-80 pubmed
    ..The reported results emphasizes the important role that the embryo-derived host regulation factors may have in parasitism success in Hymenoptera koinobionts...
  6. Goltsev Y, Fuse N, Frasch M, Zinzen R, Lanzaro G, Levine M. Evolution of the dorsal-ventral patterning network in the mosquito, Anopheles gambiae. Development. 2007;134:2415-24 pubmed
    ..melanogaster embryo. Evidence is presented that this expanded signaling is due to altered expression of the sog gene...
  7. Panfilio K. Extraembryonic development in insects and the acrobatics of blastokinesis. Dev Biol. 2008;313:471-91 pubmed
  8. Soga K, Ichikawa D, Yasukawa S, Kubota T, Kikuchi S, Fujiwara H, et al. Prognostic impact of the width of subserosal invasion in gastric cancer invading the subserosal layer. Surgery. 2010;147:197-203 pubmed publisher
    ..We hypothesized that the horizontal width of spread of the neoplasm in the subserosal layer correlated with frequency of latent tumor exposure to the subserosal surface in subserosal (ss) gastric cancer...
  9. Takeuchi T, Iwasaki S, Miyazaki J, Nozaki Y, Takahashi M, Ono M, et al. Matrix metalloproteinase-1 expression in splenic angiosarcoma metastasizing to the serous membrane. Int J Clin Exp Pathol. 2010;3:634-9 pubmed
    Angiosarcoma involving the serous membrane may mimic mesothelioma; therefore, the term "pseudomesotheliomatous angiosarcoma" has been suggested for this entity...

More Information

Publications102 found, 100 shown here

  1. Guo L, Kuroda N, Nakayama H, Miyazaki E, Hayashi Y, Toi M, et al. Cytokeratin-positive subserosal myofibroblasts in gastroduodenal ulcer; another type of myofibroblasts. Histol Histopathol. 2006;21:697-704 pubmed publisher
    ..In contrast, in the surface layer of ulceration, stromal cells expressing only ASMA were observed. The cytokeratin-positive subserosal myofibroblastic cell in human gastroduodenal ulcer is a novel type of myofibroblast. ..
  2. Spivach A, Zanconati F, Tirabosco R, Falconieri G. Parachordoma of the gastric serosa: report of a myxoid mimicry in an unusual location. Int J Surg Pathol. 2007;15:307-10 pubmed
    ..Immunoreactivity for high-molecular-weight keratins, S100 protein, and vimentin was detected. In this report, the authors address the differential diagnosis of parachordoma and the unusual location of this neoplasm. ..
  3. Jeong O, Ryu S, Jeong M, Sun J, Park Y. Accuracy of macroscopic intraoperative diagnosis of serosal invasion and risk of over- and underestimation in gastric carcinoma. World J Surg. 2011;35:2252-8 pubmed publisher
    ..However, great care should be taken with regard to the risk of over- and underestimation of serosal invasion when making a decision for invasive treatments based on macroscopic findings of serosal invasion. ..
  4. Chattopadhyay S, Galaal K, Patel A, Fisher A, Nayar A, Cross P, et al. Tumour-free distance from serosa is a better prognostic indicator than depth of invasion and percentage myometrial invasion in endometrioid endometrial cancer. BJOG. 2012;119:1162-70 pubmed publisher
    ..01), in women who had pelvic lymphadenectomy (n = 86). A TFD cut-off of 1.75 mm showed good prognostic performance. The TFD measure may be a more accurate method of representing myometrial invasion in the staging for endometrial cancer. ..
  5. Chaudhari U, Metkari S, Manjaramkar D, Sachdeva G, Katkam R, Bandivdekar A, et al. Echography of the cervix and uterus during the proliferative and secretory phases of the menstrual cycle in bonnet monkeys (Macaca radiata). J Am Assoc Lab Anim Sci. 2014;53:18-23 pubmed
    ..43 ± 0.15 cm). Knowledge of the echogenic changes in the female reproductive organs of bonnet monkeys during a regular menstrual cycle may facilitate understanding of other physiologic and pathophysiologic changes. ..
  6. Paskaranandavadivel N, Cheng L, Du P, Rogers J, O Grady G. High-resolution mapping of gastric slow-wave recovery profiles: biophysical model, methodology, and demonstration of applications. Am J Physiol Gastrointest Liver Physiol. 2017;313:G265-G276 pubmed publisher
    ..During normal activation, RAi vs. ARi had a slope of -1, whereas the weakening of the slope indicated a dysrhythmic propagation. ..
  7. Malbec O, Roget K, Schiffer C, Iannascoli B, Dumas A, Arock M, et al. Peritoneal cell-derived mast cells: an in vitro model of mature serosal-type mouse mast cells. J Immunol. 2007;178:6465-75 pubmed
    ..These properties make PCMC a useful new model for understanding the physiopathology of mast cells in IgE- and IgG-dependent tissue inflammation. ..
  8. Moser S, Harron S, Crack J, Fawcett J, Cowley E. Multiple KCNQ potassium channel subtypes mediate basal anion secretion from the human airway epithelial cell line Calu-3. J Membr Biol. 2008;221:153-63 pubmed publisher
  9. Trischitta F, Faggio C. Gossypol affects ion transport in the isolated intestine of the seawater adapted eel, Anguilla anguilla. Comp Biochem Physiol A Mol Integr Physiol. 2008;151:139-43 pubmed publisher
    ..Since the intestine is an important organ for maintaining the water and ion balance in seawater adapted fish, it is conceivable that gossypol could impair the ability of the animals to adapt to the environment. ..
  10. Americo M, Oliveira R, Cora L, Marques R, Romeiro F, Andreis U, et al. The ACB technique: a biomagentic tool for monitoring gastrointestinal contraction directly from smooth muscle in dogs. Physiol Meas. 2010;31:159-69 pubmed publisher
    ..ACB and EMG are complementary for studying motility, with special emphasis on the colon. ACB offers an accurate method for monitoring in vivo GI motility. ..
  11. Adas G, Adas M, Arikan S, Sarvan A, Toklu A, Mert S, et al. Effect of growth hormone, hyperbaric oxygen and combined therapy on the gastric serosa. World J Gastroenterol. 2013;19:2904-12 pubmed publisher
    ..01) 3 wk after the operation. HBOT or GH and combined therapy augmented on neomucosal formation. The use of combined therapy produced a synergistic effect on the histological, morphological and functional parameters. ..
  12. Walia H, Abd el Karim H. Anterior lesser curve seromyotomy with posterior truncal vagotomy versus proximal gastric vagotomy: results of a prospective randomized trial 3-8 years after surgery. World J Surg. 1994;18:758-63 pubmed
    ..The recurrent ulcer rate was 14% for PGV and 12% for ASPTV. This trial suggests that for the treatment of duodenal ulcer ASPTV is as good an operation as PGV. ..
  13. Hand A, Pathmanathan D, Field R. Morphological features of the minor salivary glands. Arch Oral Biol. 1999;44 Suppl 1:S3-10 pubmed
    ..The role of minor salivary glands in the function and defence of the oral cavity may be better understood as a result of new physiological and molecular methods applicable to samples of limited size and availability...
  14. Nissman S, Mann B, Vitvitsky E, Fyfe B. Spontaneous nontraumatic hemoperitoneum due to a bleeding arteriovenous malformation on the serosal surface of the transverse colon: a case report. Am Surg. 2002;68:911-2 pubmed
    ..The lesion was excised and the patient recovered without sequelae. To date there have been no other documented cases of an arteriovenous malformation on the serosal surface of a visceral abdominal organ. ..
  15. Dahlman D, Rana R, Schepers E, Schepers T, DiLuna F, Webb B. A teratocyte gene from a parasitic wasp that is associated with inhibition of insect growth and development inhibits host protein synthesis. Insect Mol Biol. 2003;12:527-34 pubmed
    ..We hypothesize that some wasp parasites inhibit translation as a general means to regulate and redirect lepidopteran host physiology to support endoparasite development. ..
  16. Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Ono H, et al. Surgical outcome of serosa-negative advanced gastric carcinoma. Anticancer Res. 2004;24:3169-75 pubmed
    ..Prophylactic therapeutic strategy should be advised for patients with many metastatic lymph nodes, for peritoneal or lymphatic recurrence and in patients with "medullary" stroma for hematogenous recurrence. ..
  17. Yamaura M, Sato T, Echigo S, Takahashi N. Quantification and detection of bacteria from postoperative maxillary cyst by polymerase chain reaction. Oral Microbiol Immunol. 2005;20:333-8 pubmed
    ..It is probable that bacterial infection affects the progression of POMC symptoms. The aims of this study were to determine the bacterial density and to examine the presence of 20 oral bacteria in POMC fluids...
  18. Kim R, Falkenberg E, Pareek P. Image-based intracavitary brachytherapy in the treatment of inoperable uterine cancer: individual dose specification at specific anatomical sites. Brachytherapy. 2005;4:286-90 pubmed
    ..Image-based brachytherapy based on individualized dose specification at specific anatomical sites can be done easily and provides excellent local control for inoperable uterine cancer. ..
  19. Stewart C, Morris M, De Boer B, Iacopetta B. Identification of serosal invasion and extramural venous invasion on review of Dukes' stage B colonic carcinomas and correlation with survival. Histopathology. 2007;51:372-8 pubmed
    ..The revised assessment correlated with patient outcome. Reliable identification of these features may permit stratification of high-risk patients with Dukes' stage B colonic cancer who could benefit from adjuvant treatment. ..
  20. Lemke S, Schmidt Ott U. Evidence for a composite anterior determinant in the hover fly Episyrphus balteatus (Syrphidae), a cyclorrhaphan fly with an anterodorsal serosa anlage. Development. 2009;136:117-27 pubmed publisher
    ..We discuss our findings in a phylogenetic context and propose that Episyrphus employs a primitive cyclorrhaphan mechanism of AP axis specification. ..
  21. Seki A, Maeshima A, Nakagawa H, Shiraishi J, Murata Y, Arai H, et al. A subserosal uterus-like mass presenting after a sliding hernia of the ovary and endometriosis: a rare entity with a discussion of the histogenesis. Fertil Steril. 2011;95:1788.e15-9 pubmed publisher
    ..To report the first case of a subserosal uterus-like mass...
  22. Jahreis G, Wohlgemuth S, Grünz G, Martin L, Knieling M, Engel R, et al. Dietary crystalline common-, micro-, nanoscale and emulsified nanoscale sitosterol reduce equally the cholesterol pool in guinea pigs, but varying nanosystems result in different sterol concentrations in serosal jejunum. Nanomedicine. 2013;9:1027-35 pubmed publisher
  23. Murakumo M, Ushiki T, Abe K, Matsumura K, Shinno Y, Koyanagi T. Three-dimensional arrangement of collagen and elastin fibers in the human urinary bladder: a scanning electron microscopic study. J Urol. 1995;154:251-6 pubmed
    ..The arrangements of these components were discussed in relation to the mechanical function and compliance of the urinary bladder. ..
  24. Freud E, Eshet R. Insights from animal models for growing intestinal neomucosa with serosal patching--a still untapped technique for the treatment of short bowel syndrome. Lab Anim. 2001;35:180-7 pubmed
  25. Inglis S, Finlay L, Ramminger S, Richard K, Ward M, Wilson S, et al. Regulation of intracellular pH in Calu-3 human airway cells. J Physiol. 2002;538:527-39 pubmed
    ..RT-PCR detected the expression of the electrogenic Na(+)-HCO(3)(-) cotransporter NBC1 and the Cl(-)-HCO(3)(-) exchanger (AE2) but not the electroneutral Na(+)-HCO(3)(-) cotransporter NBCn1. ..
  26. Mineo H, Hara H, Tomita F. Sugar alcohols enhance calcium transport from rat small and large intestine epithelium in vitro. Dig Dis Sci. 2002;47:1326-33 pubmed
    ..We concluded that sugar alcohols directly affect the epithelial tissue and promote Ca absorption from the small and large intestine in vitro. ..
  27. Yoshikawa T, Tsuburaya A, Kobayashi O, Sairenji M, Motohashi H, Noguchi Y. Peritoneal cytology in patients with gastric cancer exposed to the serosa--a proposed new classification based on the local and distant cytology. Hepatogastroenterology. 2003;50:1183-6 pubmed
    ..Peritoneal cytology should be evaluated not only at a distant site, but also locally to identify the subset of patients with limited peritoneal dissemination. ..
  28. Mardones P, Andrinolo D, Csendes A, Lagos N. Permeability of human jejunal segments to gonyautoxins measured by the Ussing chamber technique. Toxicon. 2004;44:521-8 pubmed
    ..These findings suggests that permeability of gonyautoxins depends on temperature and processes involving sodium ion. Replacing sodium ions by choline ions showed a marked effect on TER. ..
  29. Hamauzu T, Kuroda N, Guo L, Miyazaki E, Hayashi Y, Toi M, et al. CAM5.2-positive subserosal myofibroblasts in appendicitis. Med Mol Morphol. 2006;39:209-13 pubmed
    ..Finally, many myofibroblasts appearing in the subserosal area of the perforation of appendicitis may be derived from submesothelial cells or mesothelial cells. ..
  30. Johnatty S, Beesley J, Chen X, Spurdle A, deFazio A, Webb P, et al. Polymorphisms in the FGF2 gene and risk of serous ovarian cancer: results from the ovarian cancer association consortium. Twin Res Hum Genet. 2009;12:269-75 pubmed publisher
    ..Overall genetic variation in FGF2 does not appear to play a role in susceptibility to ovarian cancer. ..
  31. Panfilio K, Roth S. Epithelial reorganization events during late extraembryonic development in a hemimetabolous insect. Dev Biol. 2010;340:100-15 pubmed publisher
    ..These data also address the long-standing question of the final fate of the amnion: it undergoes apoptosis during dorsal closure and thus is likely to be solely extraembryonic...
  32. Loeschke K, Bentzel C. Osmotic water flow pathways across Necturus gallbladder: role of the tight junction. Am J Physiol. 1994;266:G722-30 pubmed
    ..Directionally divergent pathways may account for flow asymmetry. ..
  33. Quddus M, Rashid L, Sung C, Steinhoff M, Cunxian Zhang -, Lawrence W. Ewing's sarcoma/peripheral primitive neuroectodermal tumor (ES/PNET) differentiation in endometrial serous carcinomas. Reprod Sci. 2009;16:591-5 pubmed publisher
  34. Li C, Wei Y, Xue Y. [Expression of hepatocyte growth factor, transcription factor SP1, vascular endothelial growth factor and CD34 in serosa-infiltrative gastric cancer and their relations with defluxion of gastric cancer cell and prognosis]. Zhonghua Wai Ke Za Zhi. 2009;47:206-9 pubmed
    ..The detection of these factors might be helpful in predicting the defluxion of gastric cancer cells and postoperative recurrence. ..
  35. Sikaris K. CA125--a test with a change of heart. Heart Lung Circ. 2011;20:634-40 pubmed publisher
  36. Briscoe J, Bennett R. Use of a duodenal serosal patch in the repair of a colon rupture in a female Solomon Island eclectus parrot. J Am Vet Med Assoc. 2011;238:922-6 pubmed publisher
    ..Because birds lack an omentum, serosal patching with adjacent duodenum should be considered as a viable option in avian surgery. ..
  37. Vovk T, Bogataj M, Roskar R, Kmetec V, Mrhar A. Determination of main low molecular weight antioxidants in urinary bladder wall using HPLC with electrochemical detector. Int J Pharm. 2005;291:161-9 pubmed
    ..The developed HPLC method with electrochemical detection of LMWA is simple, fast and can be used for simultaneous quantification of LMWA in tissues, which contain low concentrations of antioxidants. ..
  38. Kusum D, Semlani S, Deshpande J. Migration of steatonecrosis in pancreatitis. Indian J Pathol Microbiol. 2006;49:546-7 pubmed
    ..Saponified fatty acid crystalloids, not seen in every case, were seen in these foci of fat necrosis. ..
  39. Yasuda K, Shiraishi N, Inomata M, Shiroshita H, Izumi K, Kitano S. Prognostic significance of macroscopic serosal invasion in advanced gastric cancer. Hepatogastroenterology. 2007;54:2028-31 pubmed
    ..Clinically, knowledge of the extent of macroscopic serosal invasion is helpful in planning adjuvant chemotherapy. ..
  40. Fu C, Chang W, Yu T, Cheng M, Chen T. Unusual giant abdominal leiomyoma in a young man: a case report. Z Gastroenterol. 2008;46:421-4 pubmed publisher
    ..An abdominal leiomyoma with central hemorrhage was found on exploratory laparotomy; the tumor was completely resected. To the best of our knowledge, no similar case has been reported in the literature. ..
  41. Jacobs C, Rezende G, Lamers G, van der Zee M. The extraembryonic serosa protects the insect egg against desiccation. Proc Biol Sci. 2013;280:20131082 pubmed publisher
    ..We propose that the origin of this extraembryonic membrane facilitated the spectacular radiation of insects on land, as did the origin of the amniote egg in the terrestrial invasion of vertebrates...
  42. Hilbrant M, Horn T, Koelzer S, Panfilio K. The beetle amnion and serosa functionally interact as apposed epithelia. elife. 2016;5: pubmed publisher
    ..This EE strategy may reflect evolutionary changes within the holometabolous insects and serves as a model to study interactions between developing epithelia. ..
  43. Miyazaki T, Inoue Y, Takano K. Seromucous cells in human sublingual glands: examination by immunocytochemistry of lysozyme. Arch Histol Cytol. 2001;64:305-12 pubmed
    ..The present study demonstrated that the seromucous cells in the human sublingual glands conform closely with those in the human labial glands (MIYAZAKI et. al., 1998)...
  44. Terreni A, Nosi D, Greven H, Delfino G. Development of serous cutaneous glands in Scinax nasica (Anura, Hylidae): patterns of poison biosynthesis and maturation in comparison with larval glands in specimens of other families. Tissue Cell. 2003;35:274-87 pubmed
  45. Yeh D, Cheng S, Yu C, Ho W, Wu C, Liu T, et al. Role of glucocorticoid receptor in serosa-involved gastric carcinoma after gastrectomy. J Gastrointest Surg. 2006;10:706-11 pubmed
    ..GR-positive gastric cancer had a worse survival rate than GR-negative gastric cancer. Multimodality adjuvant therapies should be considered in patients with GR-positive serosa-involved gastric carcinoma...
  46. Fischer H, Illek B, Sachs L, Finkbeiner W, Widdicombe J. CFTR and calcium-activated chloride channels in primary cultures of human airway gland cells of serous or mucous phenotype. Am J Physiol Lung Cell Mol Physiol. 2010;299:L585-94 pubmed publisher
  47. Badmos K, Seada L, Faraj A. Heterotopic ossification in a colorectal carcinoma. J Coll Physicians Surg Pak. 2011;21:626-7 pubmed publisher
    ..From the available literature reviewed and to the best of our knowledge, this is the first reported case of mucinous colorectal carcinoma with heterotopic ossification in Saudi Arabia...
  48. Chung Y, Yamashita Y, Kato Y, Nakata B, Sawada T, Sowa M. Prognostic significance of T antigen expression in patients with gastric carcinoma. Cancer. 1996;77:1768-73 pubmed
    ..In this study, we determined the prognostic significance of T antigen in specimens with gastric carcinoma...
  49. Wang L, Chu D, Dokun A, Yokoyama W. Inducible expression of the gp49B inhibitory receptor on NK cells. J Immunol. 2000;164:5215-20 pubmed
  50. Lee W, Lee M, Jeen Y, Kie J, Chung J, Yun S. Solitary fibrous tumor arising in gastric serosa. Pathol Int. 2004;54:436-9 pubmed
    ..Although its occurrence is rare, SFT should be considered in the differential diagnosis of mesenchymal tumors of the stomach...
  51. Routh J, Wolpert J, Reinberg Y. Tunneled tunica vaginalis flap is an effective technique for recurrent urethrocutaneous fistulas following tubularized incised plate urethroplasty. J Urol. 2006;176:1578-80; discussion 1581 pubmed
    ..However, to our knowledge its use after tubularized incised plate repair has not yet been described. We present our results with this technique...
  52. Petricevic J, Punda H, Brakus S, Vukojevic K, Govorko D, Alfirevic D, et al. Immunolocalization of nestin, mesothelin and epithelial membrane antigen (EMA) in developing and adult serous membranes and mesotheliomas. Acta Histochem. 2012;114:469-79 pubmed publisher
    ..We speculate that submesothelial pericardial and mesothelial pleural cells might belong to a population of stem cells. In epithelioid mesotheliomas, 13% of cells expressed nestin, 39% EMA and 7% mesothelin...
  53. Kishi K, Fujiwara Y, Yano M, Inoue M, Miyashiro I, Motoori M, et al. Staging laparoscopy using ALA-mediated photodynamic diagnosis improves the detection of peritoneal metastases in advanced gastric cancer. J Surg Oncol. 2012;106:294-8 pubmed publisher
    ..This study evaluated the usefulness of photodynamic diagnosis (PDD) using oral 5-aminolevulinic acid (ALA) for the detection of peritoneal metastases in advanced gastric cancer...
  54. Avvisati G. [Primary lymphoma of the serous body cavities]. Clin Ter. 2004;155:487-8 pubmed
  55. Xue L, Locke G, Camilleri M, Schuurkes J, Meulemans A, Coulie B, et al. Effect of modulation of serotonergic, cholinergic, and nitrergic pathways on murine fundic size and compliance measured by ultrasonomicrometry. Am J Physiol Gastrointest Liver Physiol. 2006;290:G74-82 pubmed
    ..The data suggest that ultrasonomicrometry is a useful tool that can reproducibly and accurately measure changes in fundic size and the response to pharmacological agents...
  56. Lee K, Yamataka A, Kato Y, Kobayashi H, Lane G, Maeda K, et al. Graft serosectomy in adult small bowel transplantation without vascular reconstruction in rats improves graft survival by induction of vascular endothelial growth factor. J Pediatr Surg. 2005;40:1881-6 pubmed
    ..The aim of this study was to assess whether adult small bowel grafts (ASBGs) can survive transplantation without vascular reconstruction if graft serosectomy (SS) is performed...
  57. Bentrem D, Gerdes H, Tang L, Brennan M, Coit D. Clinical correlation of endoscopic ultrasonography with pathologic stage and outcome in patients undergoing curative resection for gastric cancer. Ann Surg Oncol. 2007;14:1853-9 pubmed
    ..The aim of this study was to correlate EUS staging with pathologic evaluation and outcome in patients undergoing curative R0 resection for gastric cancer...
  58. Zhang T, Chen J, Zhang Y, Shen Q, Pan W. Characterization and evaluation of nanostructured lipid carrier as a vehicle for oral delivery of etoposide. Eur J Pharm Sci. 2011;43:174-9 pubmed publisher
    ..The NLCs formulation remarkably improved the oral bioavailability of VP16 and demonstrated a promising perspective for oral delivery of VP16...
  59. Takii M, Tanaka H, Kuroda K, Asano Y, Sakurai K, Muguruma K, et al. [Locally recurrent case of gastric cancer with serosal invasion after four months of endoscopic submucosal dissection]. Gan To Kagaku Ryoho. 2012;39:2342-4 pubmed
    ..ESD is less invasive than open surgery, but strict observation following curative resection is essential to rule out inflammation-mediated recurrence...
  60. Kato H, Iizuka K, Igawa Y, Nishizawa O. Serous-lined extramural tunnel technique for uretero-ileal implantation in urinary diversion. Int J Urol. 1999;6:145-8 pubmed
    ..We present our initial experience of a serous-lined extramural tunnel technique for anti-refluxing uretero-ileal anastomosis in five cases of orthotopic ileal bladder and four cases of continent ileal pouch...
  61. Blanco Bruned J, Alvarez Díaz J, Sáez López A, Oliver Llinares F, Prado Fernández C, González Landa G. [Seromuscular colocystoplasty lined by urothelium. Experimental study in rats]. Cir Pediatr. 2001;14:162-7 pubmed
    ..To determine what technical of vesical extension in rat can offer the best functional and histological results...
  62. Jabar M, Shaker A, Gul Y. Spontaneous haemoperitoneum secondary to a Meckel's diverticulum. Acta Chir Belg. 2004;104:596-8 pubmed
    ..The diverticulum was routinely excised. It was macroscopically and histologically devoid of inflammation. The bleeding vessel was not found to be abnormal or part of an arteriovenous malformation...
  63. Josefsson M, Evilevitch L, Weström B, Grunditz T, Ekblad E. Sodium-iodide symporter mediates iodide secretion in rat gastric mucosa in vitro. Exp Biol Med (Maywood). 2006;231:277-81 pubmed
    ..We conclude that iodide is actively transported into the gastric lumen and that this transport is at least partly mediated by NIS. Additional investigations are needed to understand the regulation and significance of this transport...
  64. Grimes J, Schmiedt C, Milovancev M, Radlinsky M, Cornell K. Efficacy of serosal patching in dogs with septic peritonitis. J Am Anim Hosp Assoc. 2013;49:246-9 pubmed publisher
    ..2%) died prior to discharge (P = 0.34). Use of a serosal patch did not protect dogs from either postoperative septic peritonitis or failure to survive. ..
  65. Calado A, Macedo A, Delcelo R, de Figueiredo L, Ortiz V, Srougi M. The tunica vaginalis dorsal graft urethroplasty: experimental study in rabbits. J Urol. 2005;174:765-70 pubmed
    ..We studied the histological and radiological characteristics of free tunica vaginalis graft urethroplasty...
  66. Tan D, Agarwal R, Kaye S. Mechanisms of transcoelomic metastasis in ovarian cancer. Lancet Oncol. 2006;7:925-34 pubmed
    ..These studies might also result in the identification of potential new therapeutic targets in ovarian cancer...
  67. Papatsenko D, Levine M, Goltsev Y. Clusters of temporal discordances reveal distinct embryonic patterning mechanisms in Drosophila and anopheles. PLoS Biol. 2011;9:e1000584 pubmed publisher
    ..We propose that gene clustering by local temporal discordance can be used for the de novo identification of the gene batteries underlying morphological diversity...
  68. Sun Z, Xu Y, Wang Z, Zhu Z, Zhang H, Huang B, et al. Macroscopic serosal classification predicts peritoneal recurrence for patients with gastric cancer underwent potentially curative surgery. Ann Surg Oncol. 2011;18:1068-80 pubmed publisher
    ..The aim of the present study was to propose a macroscopic serosal classification (MSC) and to investigate the validity of this classification as a predictor of peritoneal recurrence...
  69. Hunter S, Anglesio M, Sharma R, Gilks C, Melnyk N, Chiew Y, et al. Copy number aberrations in benign serous ovarian tumors: a case for reclassification?. Clin Cancer Res. 2011;17:7273-82 pubmed publisher
    ..This study aimed to conduct copy number (CN) analysis using a series of benign and borderline serous ovarian tumors to identify underlying genomic changes that may be indicative of early events in tumorigenesis...
  70. Teng X, Xu L, Wu J, Sun M, Guo J, Mao Z. Clinical and morphological features of serosal form of eosinophilic gastroenteritis in a retrospective study of 10 children. Fetal Pediatr Pathol. 2013;32:276-83 pubmed publisher
    ..Serosal form is one subtype of EG. The aetiology and pathogenesis of EG are unknown and the diagnosis and treatment properly are difficult for physician...
  71. Yano M, Yasuda T, Fujiwara Y, Takiguchi S, Miyata H, Monden M. Preoperative intraperitoneal chemotherapy for patients with serosa-infiltrating gastric cancer. J Surg Oncol. 2004;88:39-43 pubmed
    ..Serosa-infiltrating gastric cancer poses a high risk for peritoneal recurrence. This study examined the feasibility and efficacy of preoperative intraperitoneal (i.p.) chemotherapy for such cancer...
  72. Binnebösel M, Klinge U, Rosch R, Junge K, Lynen Jansen P, Schumpelick V. Morphology, quality, and composition in mature human peritoneal adhesions. Langenbecks Arch Surg. 2008;393:59-66 pubmed
    ..Adhesions are supposed to consist of avascular scar tissue. The aim of the present study was to analyze whether mature postsurgical adhesions even after years still reveal a dynamic remodeling process...
  73. Braga L, Pippi Salle J, Dave S, Bagli D, Lorenzo A, Khoury A. Outcome analysis of severe chordee correction using tunica vaginalis as a flap in boys with proximal hypospadias. J Urol. 2007;178:1693-7; discussion 1697 pubmed
    ..To further assess these issues we reviewed our experience with ventral penile lengthening for correcting the severe ventral curvature associated with proximal hypospadias...
  74. Azevedo J, Hypólito O, Azevedo O, Becker O, Freire D. Comparative study of hand sewn single layer anastomosis of dog's bowel. Arq Gastroenterol. 2008;45:319-22 pubmed
    ..However the four main kinds of stitches which may be chosen in performing single layer intestinal sutures never before had been comparatively studied...
  75. Park H, Hong S, Kim J, Kwon S, Kwon K, Choi D, et al. Tumor detection and serosal invasion of bladder cancer: role of three-dimensional volumetric reconstructed US. Abdom Imaging. 2010;35:265-70 pubmed publisher
    ..The purpose of this study is to evaluate the accuracy of 3D volumetric reconstructed US in the assessment of tumor detection and serosal invasion in patients with bladder cancer...
  76. Ordway G, Boheler K, Longhurst J. Stimulating intestinal afferents reflexly activates cardiovascular system in cats. Am J Physiol. 1988;254:H354-60 pubmed
    ..Furthermore, although mechanoreceptors may contribute to the responses evoked by bradykinin and bethanechol, the capsaicin-related responses likely are mediated exclusively by chemically sensitive receptors...
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    ..HPA, SBA and UEA-I are likely to be useful markers for identification of RMC and AC in cytology...
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    ..The significance of MUC 1 expression in the gallbladder tissues in relation to cancer and non-cancer disease is not well understood. The aim of this study was to clarify the significance of MUC 1 expression...
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    ..We advocate SAA as a modification of appendicectomy in patients with recurrent appendicitis where the appendix is inflamed and adherent...
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    ..We report the results of corporeal tunica vaginalis free graft for single stage correction of severe chordee in children with proximal hypospadias...
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    ..Because of its high sensitivity (99.1%) and specificity (100%), Claudin 4 might be used as an ideal "single-shot" marker for the identification of metastatic epithelial cells in serous effusions...
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    ..All the results suggest that constitutive expression of IL-17A in intestine enhances tumor growth, and anti-IL-17A antibody treatment is a candidate of a new anti-tumor immunotherapy against intestinal tumors...
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    ..Diagnosing epithelioid serosal lesions remains a challenge because numerous different processes-primary or secondary, benign or malignant-occur in body cavities, some of which are very rare...
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    ..These findings are valuable to develop an effective method of in vivo gene transfer to the stomach...
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    ..Second, hindsight might function both to maintain the amnioserosa and to regulate chemical signaling from the amnioserosa to the epidermal ectoderm, thus coordinating the cell shape changes and movements that drive germ-band retraction...
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    ..To determine the sensitivity and specificity of flow- and image-cytometry for the detection of DNA-aneuploidy as a marker for malignant cells in effusions...
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    ..We also show several examples of anatomical objects with glistening effects that mimic real anatomical objects...
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    ..In this study, the effects resulting from the presence or absence of the omentum were evaluated in the setting of infection or serosal defects in the formation of adhesions in abdominal closures using mesh grafts...
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    ..The purpose of our study was to assess the relationship between the endometrium and submucosal fibroids before and after uterine artery embolization (UAE)...
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    ..The capacity of salmeterol to restore the secretory capacity of glandular serous cells suggests that it could also improve the airway mucociliary clearance in patients with CF...
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    ..A paradigm shift with respect to the origin of ovarian cancer from the ovary to the endometrium could have enormous consequences for primary and secondary preventive strategies to decrease the mortality from this disease...
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    ..The review article highlights the contentious issues in histopathological recognition of pT4 tumour stage based on microscopic parameters in colorectal cancer...