adenoids

Summary

Summary: A collection of lymphoid nodules on the posterior wall and roof of the NASOPHARYNX.

Top Publications

  1. Drago L, Esposito S, De Vecchi E, Marchisio P, Blasi F, Baggi E, et al. Detection of respiratory viruses and atypical bacteria in children's tonsils and adenoids. J Clin Microbiol. 2008;46:369-70 pubmed
    The tonsils and adenoids of 44 children were analyzed for the detection of respiratory syncytial virus, influenza virus, parainfluenza virus, adenovirus, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. Viruses were detected in 47...
  2. Kurnatowski P, Putyński L, Łapienis M, Kowalska B. Physical and emotional disturbances in children with adenotonsillar hypertrophy. J Laryngol Otol. 2008;122:931-5 pubmed
    Enlarged tonsils and adenoids (part of Waldeyer's ring) are responsible for obstructive sleep disordered breathing...
  3. Ogasawara N, Kojima T, Go M, Takano K, Kamekura R, Ohkuni T, et al. Epithelial barrier and antigen uptake in lymphoepithelium of human adenoids. Acta Otolaryngol. 2011;131:116-23 pubmed publisher
    ..The adenoids (nasopharyngeal tonsils) comprise one of the NALTs and constitute the major part of Waldeyer's lymphoid ring in ..
  4. Zelazowska Rutkowska B, Wysocka J, Skotnicka B. Chosen factors of T and B cell apoptosis in hypertrophic adenoid in children with otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2010;74:698-700 pubmed publisher
    ..The tendency of reduced percentages of T and B lymphocytes with Bcl-2 expression and elevated percentages of these cells with CD95(+) expression within the adenoid may reflect local immunity disorders...
  5. Pagella F, Colombo A, Gatti O, Giourgos G, Matti E. Rhinosinusitis and otitis media: the link with adenoids. Int J Immunopathol Pharmacol. 2010;23:38-40 pubmed
    ..Recently some works in literature evidenced the presence of bacterial biofilms on adenoids and suggested a responsibility of bacterial biofilms in both chronic rhinosinusitis and otitis media...
  6. Piacentini G, Peroni D, Blasi F, Pescollderungg L, Goller P, Gallmetzer L, et al. Atypical bacteria in adenoids and tonsils of children requiring adenotonsillectomy. Acta Otolaryngol. 2010;130:620-5 pubmed publisher
    ..Therefore, their identification, followed by an appropriate treatment, should be considered...
  7. Winther B, Gross B, Hendley J, Early S. Location of bacterial biofilm in the mucus overlying the adenoid by light microscopy. Arch Otolaryngol Head Neck Surg. 2009;135:1239-45 pubmed publisher
    ..To determine the location of bacteria and biofilm in adenoid tissue and in mucus overlying the adenoid...
  8. Kania R, Lamers G, Vonk M, Dorpmans E, Struik J, Tran Ba Huy P, et al. Characterization of mucosal biofilms on human adenoid tissues. Laryngoscope. 2008;118:128-34 pubmed
    To demonstrate the presence of mucosal biofilm in adenoid tissue using double staining for visualization of both the bacterial matrix and the bacterial cells. To identify bacterial species present on the surface of the studied adenoids.
  9. Verbrugghe P, Kujala P, Waelput W, Peters P, Cuvelier C. Clusterin in human gut-associated lymphoid tissue, tonsils, and adenoids: localization to M cells and follicular dendritic cells. Histochem Cell Biol. 2008;129:311-20 pubmed
    ..In palatine tonsils and adenoids, we demonstrated clusterin expression in germinal centers and in the lymphoepithelium in the crypts where M cells ..

More Information

Publications62

  1. Avanzini A, Castellazzi A, Marconi M, Valsecchi C, Marseglia A, Ciprandi G, et al. Children with recurrent otitis show defective IFN gamma-producing cells in adenoids. Pediatr Allergy Immunol. 2008;19:523-6 pubmed publisher
    ..Intracellular cytokine profile of lymphocyte subsets in adenoids and peripheral blood was evaluated by flow cytometry analysis...
  2. Lu X, Gooding L, Erdman D. Human bocavirus in tonsillar lymphocytes. Emerg Infect Dis. 2008;14:1332-4 pubmed publisher
  3. Granath A, Uddman R, Cardell L. Increased TLR7 expression in the adenoids among children with otitis media with effusion. Acta Otolaryngol. 2010;130:57-61 pubmed publisher
    Toll-like receptor 7 (TLR7) is present in the adenoids in young children and might play a role in the immunological response behind the development of otitis media with effusion (OME).
  4. Jonsson A, Papadogiannakis N, Granath A, Haggstrom J, Schaffer M, Uzunel M, et al. Maternal microchimerism in juvenile tonsils and adenoids. Pediatr Res. 2010;68:199-204 pubmed publisher
    ..The aim of this study was to investigate the occurrence of maternal cells in tonsils and adenoids of 20 healthy children between the ages of 2 and 15 years...
  5. Kolo E, Ahmed A, Kazeem M, Nwaorgu O. Plain radiographic evaluation of children with obstructive adenoids. Eur J Radiol. 2011;79:e38-41 pubmed publisher
    ..There are several methods of evaluating adenoidal size pre-operatively. Plain nasopharyngeal radiography is a common investigative modality: it has been advocated, and also condemned...
  6. Nistico L, Kreft R, Gieseke A, Coticchia J, Burrows A, Khampang P, et al. Adenoid reservoir for pathogenic biofilm bacteria. J Clin Microbiol. 2011;49:1411-20 pubmed publisher
    ..Controlled studies indicate that adenoidectomy is effective in the treatment of COM, suggesting that the adenoids may act as a reservoir for COM pathogens...
  7. Sade K, Fishman G, Kivity S, DeRowe A, Langier S. Expression of Th17 and Treg lymphocyte subsets in hypertrophied adenoids of children and its clinical significance. Immunol Invest. 2011;40:657-66 pubmed publisher
    ..the adenoidal lymphocyte subsets to describe the percentage of various lymphocyte subsets in hypertrophied adenoids and correlate them with symptom severity...
  8. Heo K, Hur D, Park S, Yang Y, Kwak H, Kim T. Expression of chitinases in hypertrophied adenoids of children. Otolaryngol Head Neck Surg. 2011;145:660-5 pubmed publisher
    ..effusion (OME), and allergic rhinitis (AR) are common conditions that have been associated with hypertrophied adenoids in children, and adenoidectomy is clinically recommended...
  9. Cassano P, Cassano M. Otitis media and immunological alterations of Waldeyer's ring. Adv Otorhinolaryngol. 2011;72:164-9 pubmed publisher
    In the literature, correlations between adenoids and middle ear disorders have been widely discussed over the years...
  10. Marseglia G, Caimmi D, Pagella F, Matti E, Labò E, Licari A, et al. Adenoids during childhood: the facts. Int J Immunopathol Pharmacol. 2011;24:1-5 pubmed
    b>Adenoids are constantly exposed to viral and bacterial agents as well as to allergens. They play a major role in the upper airways immunity, being effector organs in both mucosal-type and systemic-type adaptive immunity...
  11. Marseglia G, Avanzini M, Caimmi S, Caimmi D, Marseglia A, Valsecchi C, et al. Passive exposure to smoke results in defective interferon-gamma production by adenoids in children with recurrent respiratory infections. J Interferon Cytokine Res. 2009;29:427-32 pubmed publisher
    ..The intracellular cytokine profile of lymphocyte subsets in adenoids was evaluated by flow cytometry analysis...
  12. Takano K, Kojima T, Ogasawara N, Go M, Kikuchi S, Ninomiya T, et al. Expression of tight junction proteins in epithelium including Ck20-positive M-like cells of human adenoids in vivo and in vitro. J Mol Histol. 2008;39:265-73 pubmed publisher
    ..These results indicate that the epithelial barrier of the human adenoid is stably maintained by expression of tight junction proteins in the epithelium including Ck20-positive M-like cells...
  13. Papatziamos G, van der Ploeg I, Hemlin C, Patwardhan A, Scheynius A. Increased occurrence of IgE+ and FcepsilonRI+ cells in adenoids from atopic children. Allergy. 1999;54:916-25 pubmed
    To examine the influence of atopy on the different cell populations in adenoids, we investigated the presence of IgE+ cells, cells expressing the high-affinity receptor for IgE (Fc(epsilon)RI), and various other cell populations in ..
  14. Boyaka P, Wright P, Marinaro M, Kiyono H, Johnson J, Gonzales R, et al. Human nasopharyngeal-associated lymphoreticular tissues. Functional analysis of subepithelial and intraepithelial B and T cells from adenoids and tonsils. Am J Pathol. 2000;157:2023-35 pubmed
    Subepithelial and intraepithelial lymphocytes of human adenoids and tonsils were characterized and directly compared to determine the potential contribution of these tissues to mucosal and systemic immune responses...
  15. Mason P, Adam E, Prior M, Warner J, Randall C. Effect of bacterial endotoxin and middle ear effusion on ciliary activity: implications for otitis media. Laryngoscope. 2002;112:676-80 pubmed
    ..We hypothesized that endotoxin or the bacterial products in middle ear fluid in otitis media with effusion would adversely affect ciliary activity, thereby contributing to the pathogenesis of the disease...
  16. Avanzini M, Ricci A, Scaramuzza C, Semino L, Pagella F, Castellazzi A, et al. Deficiency of INFgamma producing cells in adenoids of children exposed to passive smoke. Int J Immunopathol Pharmacol. 2006;19:609-16 pubmed
    ..The aim of the present study is to evaluate the intracellular cytokine profile in adenoids and peripheral blood cells of children exposed to passive smoke...
  17. Brook I, Shah K. Bacteriology of adenoids and tonsils in children with recurrent adenotonsillitis. Ann Otol Rhinol Laryngol. 2001;110:844-8 pubmed
    b>Adenoids and tonsils electively removed from 25 children with a history of recurrent group A beta-hemolytic streptococci (GABHS) adenotonsillitis were cultured for aerobic and anaerobic bacteria...
  18. Arita M, Kodama S, Suzuki M, Mogi G. Single cell analysis of adenoid CD5+ B cells and their protective contributions to nasopharyngeal immunity. Laryngoscope. 2003;113:484-91 pubmed
    ..In the present study, the contribution of adenoid CD5+ B cells to nasopharyngeal immunity at the single cell level was investigated...
  19. Brook I, Shah K. Effect of amoxicillin or clindamycin on the adenoids bacterial flora. Otolaryngol Head Neck Surg. 2003;129:5-10 pubmed
    ..They were divided into 3 groups of 15 each to receive either no therapy (control) or 10 days of therapy with Am or C. Core adenoid tissues was quantitatively cultured for aerobic and anaerobic bacteria...
  20. Greenfeld M, Tauman R, DeRowe A, Sivan Y. Obstructive sleep apnea syndrome due to adenotonsillar hypertrophy in infants. Int J Pediatr Otorhinolaryngol. 2003;67:1055-60 pubmed
    ..The peak age for adenoid and tonsillar hypertrophy and related OSAS is 3-6 years. It has been suggested that OSAS due to ATH is extremely rare in infants. The purpose of the present study was to delineate OSAS due to ATH in infants...
  21. Brandtzaeg P. Immunology of tonsils and adenoids: everything the ENT surgeon needs to know. Int J Pediatr Otorhinolaryngol. 2003;67 Suppl 1:S69-76 pubmed
    The lymphoid tissue of Waldeyer's ring, and particularly the nasopharyngeal tonsil (adenoids), appears to be functionally comparable to nasal-associated lymphoid tissue in rodents...
  22. Zhang Q, Bernatoniene J, Bagrade L, Paton J, Mitchell T, Hammerschmidt S, et al. Regulation of production of mucosal antibody to pneumococcal protein antigens by T-cell-derived gamma interferon and interleukin-10 in children. Infect Immun. 2006;74:4735-43 pubmed
    Nasopharyngeal tonsils (adenoids) are part of human nasopharynx-associated lymphoid tissue, which may play an important role in local defense against pneumococci...
  23. Da Costa J, Navarro A, Branco Neves J, Martin M. [Otitis medias with effusion: association with the Eustachian tube dysfunction and adenoiditis. The case of the Central Hospital of Maputo]. Acta Otorrinolaringol Esp. 2005;56:290-4 pubmed
    Although the aetiology of otitis media is known to be multifactorial, adenoids infections and Eustachian tube dysfunction, have been frequently associated with the incidence of middle-ear effusion...
  24. Papatziamos G, van Hage Hamsten M, Lundahl J, Hemlin C. IgE-positive plasma cells are present in adenoids of atopic children. Acta Otolaryngol. 2006;126:180-5 pubmed
    We demonstrated the presence of IgE(+) plasma cells in the adenoids of atopic children. Our data suggest that adenoids are capable of local production of IgE and support the role of adenoids as an inductive site for allergic reactions.
  25. Havkin N, Tatum S, Shprintzen R. Velopharyngeal insufficiency and articulation impairment in velo-cardio-facial syndrome: the influence of adenoids on phonemic development. Int J Pediatr Otorhinolaryngol. 2000;54:103-10 pubmed
    ..It is hypothesized that early identification of the absence or hypoplasia of the adenoids can result in the implementation of appropriate therapy plans to avoid severe disorders of speech intelligibility.
  26. Wysocka J, Hassmann Poznanska E, Kasprzycka E, Musiatowicz M. [Lymphocyte subpopulations in the adenoids analyzed by flow cytometry]. Wiad Lek. 2001;54:418-23 pubmed
    ..The aim of the study was to evaluate the lymphocyte subpopulations in the adenoids of children with serous otitis media...
  27. Arens R, Marcus C. Pathophysiology of upper airway obstruction: a developmental perspective. Sleep. 2004;27:997-1019 pubmed
    ..This compensatory response appears to be blunted in children with OSAS. Further research is needed to fully understand the complexities of upper airway structure and function during both normal development and disease...
  28. Karlidag T, Demirdag K, Kaygusuz I, Ozden M, Yalcin S, Ozturk L. Resistant bacteria in the adenoid tissues of children with otitis media with effusion. Int J Pediatr Otorhinolaryngol. 2002;64:35-40 pubmed
    ..To investigate the relationship between the resistant bacteria in the adenoid tissue and the middle ear effusion of children who underwent myringotomy and adenoidectomy with the diagnosis of otitis media with effusion (OME)...
  29. Zhang Q, Bernatoniene J, Bagrade L, Pollard A, Mitchell T, Paton J, et al. Serum and mucosal antibody responses to pneumococcal protein antigens in children: relationships with carriage status. Eur J Immunol. 2006;36:46-57 pubmed
    ..Antibodies to CbpA and Ply may protect children aged 2 years and older against pneumococcal colonization. Adenoids may be important local induction and effector sites for both mucosal and systemic antibody production to ..
  30. Garnett C, Erdman D, Xu W, Gooding L. Prevalence and quantitation of species C adenovirus DNA in human mucosal lymphocytes. J Virol. 2002;76:10608-16 pubmed
    ..These findings suggest that human mucosal T lymphocytes may harbor species C adenoviruses in a quiescent, perhaps latent form...
  31. Pires M, Di Francesco R, Grumach A, Mello J. Evaluation of inspiratory pressure in children with enlarged tonsils and adenoids. Braz J Otorhinolaryngol. 2005;71:598-601 pubmed
    Children with enlarged tonsils and adenoids usually present breathing abnormalities such as snoring, mouth breathing and sleep apnea. It is known that upper airway obstruction and consequent mouth breathing may result in pulmonary diseases...
  32. Brook I. Effects of antimicrobial therapy on the microbial flora of the adenoids. J Antimicrob Chemother. 2003;51:1331-7 pubmed
    The core of the adenoids contains polymicrobial aerobic and anaerobic flora and also includes potential respiratory pathogens...
  33. Valera F, Travitzki L, Mattar S, Matsumoto M, Elias A, Anselmo Lima W. Muscular, functional and orthodontic changes in pre school children with enlarged adenoids and tonsils. Int J Pediatr Otorhinolaryngol. 2003;67:761-70 pubmed
    Hypertrophy of the adenoids and palatine tonsils is the second most frequent cause of upper respiratory obstruction and, consequently, mouth breathing in children...
  34. Erdag T, Ecevit M, Guneri E, Dogan E, Ikiz A, Sutay S. Pathologic evaluation of routine tonsillectomy and adenoidectomy specimens in the pediatric population: is it really necessary?. Int J Pediatr Otorhinolaryngol. 2005;69:1321-5 pubmed
    ..To evaluate the necessity of histopathologic examination for routine tonsillectomy and/or adenoidectomy in terms of unexpected malignancy by evaluating a large group of pediatric patients retrospectively with review of the literature...
  35. Orenstein J, Wahl S. The macrophage origin of the HIV-expressing multinucleated giant cells in hyperplastic tonsils and adenoids. Ultrastruct Pathol. 1999;23:79-91 pubmed
    ..However, similar cells in hyperplastic tonsils and adenoids from HIV+ individuals were alternatively identified as macrophages or, on the basis of the same S-100 and p55 ..
  36. Tonnaer E, Rijkers G, Meis J, Klaassen C, Bogaert D, Hermans P, et al. Genetic relatedness between pneumococcal populations originating from the nasopharynx, adenoid, and tympanic cavity of children with otitis media. J Clin Microbiol. 2005;43:3140-4 pubmed
    ..Bacteria involved in this process most likely originate from the nasopharynx since they show a close genetic relatedness with their nasopharyngeal counterparts...
  37. Dayyat E, Kheirandish Gozal L, Sans Capdevila O, Maarafeya M, Gozal D. Obstructive sleep apnea in children: relative contributions of body mass index and adenotonsillar hypertrophy. Chest. 2009;136:137-144 pubmed publisher
    ..The obesity epidemic has prompted remarkable changes in the proportion of obese children who are referred for habitual snoring. However, the contribution of obesity to adenotonsillar hypertrophy remains undefined...
  38. Medeiros N, Gaffrée G. Accidental displacement of inferior third molar into the lateral pharyngeal space: case report. J Oral Maxillofac Surg. 2008;66:578-80 pubmed publisher
  39. Oztürk O, Polat S. Comparison of transoral power-assisted endoscopic adenoidectomy to curettage adenoidectomy. Adv Ther. 2012;29:708-21 pubmed publisher
    ..The success of an adenoidectomy has been evaluated by assessing the amount of reduction in the adenoid size and the symptomatic improvement at the sixth postoperative month...
  40. Ozcan C, Vayisoglu Y, Otag F, Polat A, Gorur K, Ismi O. Does Helicobacter pylori have a role in the development of chronic otitis media with effusion? A preliminary study. J Otolaryngol Head Neck Surg. 2009;38:526-31 pubmed
    ..To investigate the possible relationship between chronic otitis media with effusion (COME) and Helicobacter pylori (HP)...
  41. Shin S, Choi G, Park H, Lee K, Kim S, Cho J. Immunological investigation in the adenoid tissues from children with chronic rhinosinusitis. Otolaryngol Head Neck Surg. 2009;141:91-6 pubmed publisher
  42. Dong Y, Meng L, Wang Y, Zhang J, Zhao G, Ma C. The effect of remifentanil on the incidence of agitation on emergence from sevoflurane anaesthesia in children undergoing adenotonsillectomy. Anaesth Intensive Care. 2010;38:718-22 pubmed
    ..01). In preschool-aged children undergoing adenotonsillectomy with sevoflurane general anaesthesia, after propofol and fentanyl induction, intraoperative remifentanil decreased the incidence of emergence agitation...
  43. Al Sebeih K, Katchy K. Adenotonsillar granuloma: histopathological correlation. Med Princ Pract. 2007;16:450-3 pubmed
    ..This study was undertaken to investigate the presence and nature of granulomatous changes in the adenotonsillar tissues and their relation to systemic disorders...
  44. Fernandes A, Alcântara T, D Avila D, D Avila J. Study of weight and height development in children after adenotonsillectomy. Braz J Otorhinolaryngol. 2008;74:391-4 pubmed
  45. Arrarte J, Lubianca Neto J, Fischer G. The effect of adenotonsillectomy on oxygen saturation in children with sleep breathing disorders. Int J Pediatr Otorhinolaryngol. 2007;71:973-8 pubmed
    ..To evaluate the effect of adenotonsillectomy on the oxygen saturation measures by nocturnal pulse oximetry in children with sleep breathing disorders (SBD)...
  46. Berlucchi M, Valetti L, Parrinello G, Nicolai P. Long-term follow-up of children undergoing topical intranasal steroid therapy for adenoidal hypertrophy. Int J Pediatr Otorhinolaryngol. 2008;72:1171-5 pubmed publisher
    ..Up to now, no data are available about outcomes of such therapy after long-term follow-up. We evaluated the utility of mometasone furoate aqueous nasal spray in children with adenoidal hypertrophy in long-term maintenance therapy...
  47. Strauss T, Sin S, Marcus C, Mason T, McDonough J, Allen J, et al. Upper airway lymphoid tissue size in children with sickle cell disease. Chest. 2012;142:94-100 pubmed publisher
    ..It has been speculated that overgrowth of the adenoid and tonsils is an important contributor...
  48. Macari A, Bitar M, Ghafari J. New insights on age-related association between nasopharyngeal airway clearance and facial morphology. Orthod Craniofac Res. 2012;15:188-97 pubmed publisher
    ..To evaluate the relation between adenoid hypertrophy and facial morphology across age in a pediatric population...
  49. Çiftel M, Demir B, Kozan G, Yılmaz O, Kahveci H, Kılıç Ã. Evaluation of carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy. World J Pediatr. 2016;12:103-8 pubmed publisher
    ..The present study revealed increased carotid intima-media thickness in children with adenotonsillar hypertrophy. The risk of subclinical atherosclerosis may be higher in children with adenotonsillar hypertrophy. ..
  50. Nguyen C, Parikh S, Bent J. Comparison of intraoperative bleeding between microdebrider intracapsular tonsillectomy and electrocautery tonsillectomy. Ann Otol Rhinol Laryngol. 2009;118:698-702 pubmed
    ..We sought to assess the quantity of intraoperative bleeding from microdebrider intracapsular tonsillectomy (IT) relative to electrocautery tonsillectomy (ET)...
  51. Olusesi A, Undie N, Amodu J. Allergy history as a predictor of early onset adenoids/adenotonsillar hypertrophy among Nigerian children. Int J Pediatr Otorhinolaryngol. 2013;77:1032-5 pubmed publisher
    ..Very little is known about the association of history of allergy with timing of first presentation in adenotonsillitis patients...
  52. Grandi D. The "Interdisciplinary Orofacial Examination Protocol for Children and Adolescents": a resource for the interdisciplinary assessment of the stomatognatic system. Int J Orofacial Myology. 2012;38:15-26 pubmed
  53. Berlucchi M, Sessa M. Can adenoidal hypertrophy be treated with intranasal steroids?. Rev Recent Clin Trials. 2010;5:123-7 pubmed
    ..e., alteration of the immunological system, postoperative bleeding, and recurrence of adenoids) are object of criticism...