salivary ducts

Summary

Summary: Any of the ducts which transport saliva. Salivary ducts include the parotid duct, the major and minor sublingual ducts, and the submandibular duct.

Top Publications

  1. Jamal A, Sun Z, Chen X, Zhao Y. Salivary duct carcinoma of the parotid gland: case report and review of the literature. J Oral Maxillofac Surg. 2008;66:1708-13 pubmed publisher
  2. Ohno K, Hattori T, Kagami H, Ueda M. Effects of preceding sialadenitis on the development of autoimmunity against salivary gland. Oral Dis. 2007;13:158-62 pubmed
    ..Here, we examined the effects of preceding inflammation of the salivary gland at the onset of autoimmunity against the salivary gland...
  3. Weon Y, Park S, Kim H, Jeong H, Ko Y, Park I, et al. Salivary duct carcinomas: clinical and CT and MR imaging features in 20 patients. Neuroradiology. 2012;54:631-40 pubmed publisher
    ..Salivary duct carcinoma (SDC) is an uncommon high grade adenocarcinoma of the salivary gland with a grave prognosis. The aim of this study was to investigate the clinical and CT and MR imaging features of SDC...
  4. Osailan S, Proctor G, McGurk M, Paterson K. Intraoral duct ligation without inclusion of the parasympathetic nerve supply induces rat submandibular gland atrophy. Int J Exp Pathol. 2006;87:41-8 pubmed
    ..It can be concluded that most of the atrophy induced by duct ligation is independent of damage caused to the parasympathetic nerve supply, although the latter causes a greater atrophy presumably due to denervation...
  5. Ko Y, Roh J, Son Y, Chung M, Jang J, Byun H, et al. Expression of mitotic checkpoint proteins BUB1B and MAD2L1 in salivary duct carcinomas. J Oral Pathol Med. 2010;39:349-55 pubmed publisher
    ..We aimed here to investigate the expression of mitotic checkpoint proteins benzimidazole 1 homolog beta (BUB1B) and mitosis arrest-deficient 2 like 1 (MAD2L1) in SDCs and to determine their possible role as surrogate prognostic markers...
  6. Williams M, Roberts D, Kies M, Mao L, Weber R, El Naggar A. Genetic and expression analysis of HER-2 and EGFR genes in salivary duct carcinoma: empirical and therapeutic significance. Clin Cancer Res. 2010;16:2266-74 pubmed publisher
    ..Because of the potential utilization of these markers as treatment targets, we evaluated protein and gene status by several techniques to determine complementary value...
  7. Takahashi S, Shinzato K, Nakamura S, Domon T, Yamamoto T, Wakita M. Cell death and cell proliferation in the regeneration of atrophied rat submandibular glands after duct ligation. J Oral Pathol Med. 2004;33:23-9 pubmed
    ..The present study aimed to clarify the proliferation and apoptosis of parenchymal cells during regeneration of rat submandibular glands following atrophy...
  8. Giger R, Mhawech P, Marchal F, Lehmann W, Dulguerov P. Mucoepidermoid carcinoma of Stensen's duct: a case report and review of the literature. Head Neck. 2005;27:829-33 pubmed
    ..Mucoepidermoid carcinoma of Stensen's duct is a rare neoplasm, with only five cases reported in the literature...
  9. Qi S, Liu X, Wang S. Sialoendoscopic and irrigation findings in chronic obstructive parotitis. Laryngoscope. 2005;115:541-5 pubmed
    ..To study the sialographic changes related to sialoendoscopic and irrigation fluid findings in chronic obstructive parotitis...

More Information

Publications62

  1. Piao S, Zhao S, Guo F, Xue J, Yao G, Wei Z, et al. Increased expression of CD147 and MMP-9 is correlated with poor prognosis of salivary duct carcinoma. J Cancer Res Clin Oncol. 2012;138:627-35 pubmed publisher
    ..The aim of this study was to investigate expression of CD147 and MMP-9 in salivary duct carcinoma (SDC) so as to determine whether these two genes may be correlated with poor prognosis of SDC...
  2. Salovaara E, Hakala O, Back L, Koivunen P, Saarilahti K, Passador Santos F, et al. Management and outcome of salivary duct carcinoma in major salivary glands. Eur Arch Otorhinolaryngol. 2013;270:281-5 pubmed publisher
    ..Diagnostics and management of these tumours need to be centralized in experienced surgical Head and Neck Oncology Centres, and new treatment strategies should be investigated...
  3. Takahashi S, Shinzato K, Domon T, Yamamoto T, Wakita M. Mitotic proliferation of myoepithelial cells during regeneration of atrophied rat submandibular glands after duct ligation. J Oral Pathol Med. 2004;33:430-4 pubmed
    ..The purpose of the present study was to elucidate whether myoepithelial cells proliferate mitotically during regeneration of rat submandibular glands after atrophy...
  4. Hille C, Walz B. Dopamine-induced graded intracellular Ca2+ elevation via the Na+Ca2+ exchanger operating in the Ca2+-entry mode in cockroach salivary ducts. Cell Calcium. 2006;39:305-11 pubmed
    ..These results indicate that dopamine induces a massive NKCC-mediated elevation in [Na(+)](i), which reverses the NCE activity into the reverse mode causing a graded [Ca(2+)](i) elevation in the duct cells...
  5. Kashiwagi N, Takashima S, Tomita Y, Araki Y, Yoshino K, Taniguchi S, et al. Salivary duct carcinoma of the parotid gland: clinical and MR features in six patients. Br J Radiol. 2009;82:800-4 pubmed publisher
  6. Hugill J, Sala E, Hollingsworth K, Lomas D. MR sialography: the effect of a sialogogue and ductal occlusion in volunteers. Br J Radiol. 2008;81:583-6 pubmed publisher
    ..Further optimization and evaluation of this approach should lead to improvements in the MR sialography examination of patients...
  7. Jaehne M, Roeser K, Jaekel T, Schepers J, Albert N, Löning T. Clinical and immunohistologic typing of salivary duct carcinoma: a report of 50 cases. Cancer. 2005;103:2526-33 pubmed
    ..The authors analyzed the clinical, molecular, and genetic profile of SDC and identified prognostic factors...
  8. Chossegros C, Guyot L, Richard O, Barki G, Marchal F. A technical improvement in sialendoscopy to enter the salivary ducts. Laryngoscope. 2006;116:842-4 pubmed
  9. Cotroneo E, Proctor G, Paterson K, Carpenter G. Early markers of regeneration following ductal ligation in rat submandibular gland. Cell Tissue Res. 2008;332:227-35 pubmed publisher
    ..This study suggests that morphological markers of regeneration appear as early as 3 days following ligation removal...
  10. Oehlke O, Martin H, Osterberg N, Roussa E. Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. J Cell Physiol. 2011;226:638-51 pubmed publisher
    ..We have previously shown that the bicarbonate-secreting epithelium of salivary ducts responds to changes of systemic acid-base balance by adaptive redistribution of H+ and HCO3- transporters, ..
  11. Hosal A, Fan C, Barnes L, Myers E. Salivary duct carcinoma. Otolaryngol Head Neck Surg. 2003;129:720-5 pubmed
    ..Although SDC exhibits an unpredictable clinical course, total parotidectomy with neck dissection and adjunctive radiation therapy appear to be appropriate for local and regional control of this aggressive neoplasm...
  12. Lang I, Walz B. Dopamine stimulates salivary duct cells in the cockroach Periplaneta americana. J Exp Biol. 1999;202:729-38 pubmed
  13. Okumura K, Nakamura K, Hisatomi Y, Nagano K, Tanaka Y, Terada K, et al. Salivary gland progenitor cells induced by duct ligation differentiate into hepatic and pancreatic lineages. Hepatology. 2003;38:104-13 pubmed
    ..In conclusion, the multipotent progenitor cells isolated from the rat salivary gland have characteristics of tissue stem cells and can differentiate into cells of endodermal lineages...
  14. Sakamoto M, Sasano T, Higano S, Takahashi S, Nagasaka T, Yanagawa I, et al. Evaluation of pulse sequences used for magnetic resonance sialography. Dentomaxillofac Radiol. 2001;30:276-84 pubmed
    ..To determine the most appropriate sequences for the visualization of small parotid ducts in MR sialography...
  15. Takahashi S, Nakamura S, Suzuki R, Islam N, Domon T, Yamamoto T, et al. Apoptosis and mitosis of parenchymal cells in the duct-ligated rat submandibular gland. Tissue Cell. 2000;32:457-63 pubmed
    ..Submandibular gland duct ligation thus induced marked depletion of acinar cell by apoptosis and a concurrent short-lived cycle of duct cell proliferation...
  16. Uematsu T, Yamaoka M, Doto R, Tanaka H, Matsuura T, Furusawa K. Expression of ATP-binding cassette transporter in human salivary ducts. Arch Oral Biol. 2003;48:87-90 pubmed
    ..The achieved drug resistance as well as the physiological secretory function of ABC transporters could contribute to the responsiveness to chemotherapy of malignant salivary tumours...
  17. Roussa E. H+ and HCO3- transporters in human salivary ducts. An immunohistochemical study. Histochem J. 2001;33:337-44 pubmed
    The presence and cellular distribution of key H+ and HCO3- transport proteins was studied in human salivary ducts. Immunofluorescence and immunoperoxidase light microscopy was applied, using specific antibodies against the NHE1 and NHE3 ..
  18. Man Y, Ball W, Marchetti L, Hand A. Contributions of intercalated duct cells to the normal parenchyma of submandibular glands of adult rats. Anat Rec. 2001;263:202-14 pubmed
  19. Sionis S, Vedele A, Brennan P, Fanni D, Puxeddu R. Balloon catheter sialoplasty: a safety and feasibility pilot study. Br J Oral Maxillofac Surg. 2013;51:228-30 pubmed publisher
    ..By virtue of the technique histological assessment is not possible after dilatation in patients. Long-term follow up is clearly required in this rapidly evolving area of surgery...
  20. Uruga H, Fujii T, Kurosaki A, Hanada S, Takaya H, Miyamoto A, et al. [A case of pulmonary tumor thrombotic microangiopathy caused by carcinoma (salivary duct carcinoma) ex pleomorphic adenoma]. Nihon Kokyuki Gakkai Zasshi. 2010;48:463-8 pubmed
    ..Immunohistochemical staining of the tumor cells for VEGF was weakly positive. To the best of our knowledge this is the first reported case of PTTM caused by a salivary gland tumor...
  21. Zheng L, Kim E, Yu C, Yang C, Park J, Chen Z. A retrospective case series illustrating a possible association between a widened hilum and sialolith formation in the submandibular gland. J Craniomaxillofac Surg. 2013;41:648-51 pubmed publisher
    ..The purpose of this study was to explore any association between anatomical variances in the ductal system and sialolith formation using sialoendoscopy and acrylic resin replication of the ductal system...
  22. Krishnamurthy J, Krishnamurty D, Baker J, Zhen W, Lydiatt D, Ganti A. Salivary duct carcinoma responding to trastuzumab-based therapy: case report and review of the literature. Head Neck. 2013;35:E372-5 pubmed publisher
    ..Salivary duct carcinoma (SDC) is a rare malignancy with a poor prognosis. Human epidermal growth factor receptor-2 (Her-2/neu) is overexpressed in SDC and, hence, HER-2/neu targeted therapy could be an option...
  23. Jang Y, Kim S, Pai H, Park J, Lee Y, Rotaru H. Sialolipoma: case report and review of 27 cases. Oral Maxillofac Surg. 2009;13:109-13 pubmed publisher
    ..A MEDLINE literature and articles published in the Korean language in KMbase (kmbase.medric.or.kr) search was performed and the literatures were reviewed...
  24. Leecy T, Buckland M, Turner J, Earls P. The use of immunohistochemistry in the diagnosis of primary salivary duct carcinoma: three case reports. Pathology. 2008;40:434-7 pubmed publisher
  25. Yamano Y, Uzawa K, Ito H, Tanzawa H. Endoscopically assisted removal of a fish bone penetrating the parotid duct: an unusual case. J Oral Maxillofac Surg. 2014;72:1343-9 pubmed publisher
    ..The aim was to evaluate the efficacy of endoscopy-assisted surgery for treating a foreign body (fish bone) deeply embedded in the parotid duct...
  26. Ogawa Y, Kishino M, Nakazawa M, Iwai S, Ohta Y, Ishida T, et al. Adenoid cystic carcinoma associated with salivary duct cyst in the sublingual gland. J Oral Pathol Med. 2004;33:311-3 pubmed
    ..Therefore, our case has presented for the first time a direct evidence that adenoid cystic carcinoma arises from acinus/intercalated duct...
  27. Furuse C, Cury P, de Araujo N, de Araujo V. Immunoexpression of extracellular matrix proteins in human salivary gland development. Eur J Oral Sci. 2004;112:548-51 pubmed
    ..As glandular development proceeded, the lobule was gradually filled with collagens and glandular tissue...
  28. Takahashi S, Nakamura S, Domon T, Yamamoto T, Wakita M. Active participation of apoptosis and mitosis in sublingual gland regeneration of the rat following release from duct ligation. J Mol Histol. 2005;36:199-205 pubmed
    ..These observations suggest that apoptosis as well as mitosis of duct and acinar cells actively participate in and play important roles in sublingual gland regeneration...
  29. Fukushima R, Pessan J, Sampaio F, Buzalaf M. Factors associated with fluoride concentrations in whole and parotid ductal saliva. Caries Res. 2011;45:568-73 pubmed publisher
    ..This study evaluated the effect of water fluoride concentration, age, gender, geographical area and localization (urban/rural) on fluoride concentrations in whole and ductal saliva...
  30. Goicovich E, Molina C, Perez P, Aguilera S, Fernandez J, Olea N, et al. Enhanced degradation of proteins of the basal lamina and stroma by matrix metalloproteinases from the salivary glands of Sjögren's syndrome patients: correlation with reduced structural integrity of acini and ducts. Arthritis Rheum. 2003;48:2573-84 pubmed
  31. Piao S, Ma J, Wang W, Liu Y, Zhang M, Chen H, et al. Increased expression of USP22 is associated with disease progression and patient prognosis of salivary duct carcinoma. Oral Oncol. 2013;49:796-801 pubmed publisher
    ..This study examines the protein expression of USP22 in salivary duct carcinoma (SDC) in association with patient survival and other clinicopathologic parameters...
  32. Mehta R, Faquin W, Deschler D. Pathology quiz case 1. Acinic cell carcinoma of the parotid gland with ductal extension. Arch Otolaryngol Head Neck Surg. 2004;130:790, 792-3 pubmed
  33. Liu D, Jiang L, Xie X, Zhang Z, Zhang L, Yu G. Sialoendoscopy-assisted sialolithectomy for submandibular hilar calculi. J Oral Maxillofac Surg. 2013;71:295-301 pubmed publisher
    ..To assess the clinical effects of endoscopy-assisted sialolithectomy for submandibular hilar calculi...
  34. Bruch J, Setlur J. Pediatric sialendoscopy. Adv Otorhinolaryngol. 2012;73:149-52 pubmed publisher
    ..In this chapter, the technique of sialendoscopy for parotid and submandibular glands is described...
  35. Kamath V, Belur J. Benign hyperplasia of duct-associated lymphoid tissue: report of a case and review of literature. Indian J Dent Res. 2011;22:737 pubmed publisher
    ..We report a case of benign hyperplasia of DALT in the buccal mucosa of a 58-year-old male. The histogenesis and pathological implications of this tissue are discussed and the need for recognition of this entity is stressed...
  36. Morimoto Y, Tanaka T, Tominaga K, Yoshioka I, Kito S, Ohba T. Clinical application of magnetic resonance sialographic 3-dimensional reconstruction imaging and magnetic resonance virtual endoscopy for salivary gland duct analysis. J Oral Maxillofac Surg. 2004;62:1237-45 pubmed
  37. Sato K, Shimode Y, Itoi A, Ueda Y, Katsuda S. Salivary duct carcinoma of the parotid gland presenting KIT (CD117) overexpression. Histopathology. 2007;51:114-5 pubmed
  38. Muñoz Guerra M, Nieto S, Capote A, Rodriguez Campo F, Naval Gias L. Undifferentiated carcinoma arising from the Stensen's duct: a case report and review of the literature. Am J Otolaryngol. 2005;26:415-8 pubmed
    ..The diagnosis of true Stensen's duct carcinoma can be performed on the basis of clinical presentation, radiological findings, and tumor histology. Criteria for determination of origin in the duct are revised and compared with this case...
  39. Saruta J, Tsukinoki K, Sasaguri K, Ishii H, Yasuda M, Osamura Y, et al. Expression and localization of chromogranin A gene and protein in human submandibular gland. Cells Tissues Organs. 2005;180:237-44 pubmed
    ..Finally, CgA was detected in secretory granules of serous and ductal cells by immunoelectron microscopy. In conclusion, CgA in humans is produced by HSG and secreted into saliva...
  40. Schwentner I, Obrist P, Thumfart W, Sprinzl G. Distant metastasis of parotid gland tumors. Acta Otolaryngol. 2006;126:340-5 pubmed
    ..On the basis of a clinical case regarding a patient with metastatic parotid gland cancer we present a review of the literature...
  41. Pollheimer M, Pollheimer V, Eherer A, Langner C. Multifocal primary salivary-type adenocarcinoma of the esophagus. Endoscopy. 2007;39 Suppl 1:E46 pubmed
  42. Gritzmann N. [Ultrasound of the salivary glands]. Laryngorhinootologie. 2009;88:48-56; quiz 57-9 pubmed publisher
    ..In children the main differential diagnosis of salivary gland pathologies are addressed. In many diseases sonography is the first line imaging modality in assessment of salivary glands...
  43. Erbil K, Uz A, Hayran M, Mas N, Senan S, Tuncel M. The relationship of the parotid duct to the buccal and zygomatic branches of the facial nerve; an anatomical study with parameters of clinical interest. Folia Morphol (Warsz). 2007;66:109-14 pubmed
    ..16+/-1.01 centimetres of the lateral canthus. Facial nerve paralysis is the most important complication of superficial face surgery and the anatomy of this region must thus be taken into detailed consideration by surgeons...
  44. Kajikawa S, Takeuchi A, Nii A, Nakayama H, Doi K. Temporal reduction in size of salivary acinus in rats induced by theophylline. Toxicol Pathol. 2005;33:218-24 pubmed
  45. Lee J, Kwon O, Park J, Seo J. Salivary duct carcinoma of the parotid gland: is adjuvant HER-2-targeted therapy required?. J Oral Maxillofac Surg. 2014;72:1023-31 pubmed publisher
    ..Overexpression of human epidermal growth factor receptor 2 (HER-2) is characteristic of SDC. HER-2 overexpression is considered a poor prognostic marker for SDC, and anti-HER-2 therapy has been suggested as a therapeutic option...
  46. Sato A, Hisanaga Y, Inoue Y, Nagato T, Toh H. Three-dimensional structure of apical vesicles of tuft cells in the main excretory duct of the rat submandibular gland. Eur J Morphol. 2002;40:235-9 pubmed
    ..Finally, a few vesicles and tubules that were not part either of the complex or of the network, also were found...
  47. Ngu R, Brown J, Whaites E, Drage N, Ng S, Makdissi J. Salivary duct strictures: nature and incidence in benign salivary obstruction. Dentomaxillofac Radiol. 2007;36:63-7 pubmed
    ..Salivary gland obstruction is most commonly caused either by salivary calculi or duct strictures. These strictures or stenoses develop secondarily to inflammation in the duct wall and may be single or multiple...
  48. Horsburgh A, Massoud T. The salivary ducts of Wharton and Stenson: analysis of normal variant sialographic morphometry and a historical review. Ann Anat. 2013;195:238-42 pubmed publisher
    ..These reported comprehensive and detailed morphometrics are useful for therapeutic planning of luminal procedures on the salivary ducts, including sialography, sialoendoscopy, interventional therapies, and lithotripsy.
  49. Ogbureke K, Fisher L. Expression of SIBLINGs and their partner MMPs in salivary glands. J Dent Res. 2004;83:664-70 pubmed
  50. Kang S, Kim M. Lingual crevicular approach for the intraoral submandibular gland excision. Oral Maxillofac Surg. 2010;14:219-22 pubmed publisher
    ..We present an intraoral submandibular gland excision via a lingual gingival crevicular incision which may be used for a patient with molars...
  51. Papadaki M, McCain J, Kim K, Katz R, Kaban L, Troulis M. Interventional sialoendoscopy: early clinical results. J Oral Maxillofac Surg. 2008;66:954-62 pubmed publisher
    ..This article describes the early clinical experience with endoscopic salivary duct exploration and sialolithectomy in 2 medical centers...
  52. Hertel V, Bumm K, Zenk J, Bozzato A. [Ultrasound of foreign bodies in the head and neck. Cases compared with an in vitro model]. Laryngorhinootologie. 2012;91:233-9 pubmed publisher
    ..The aim of the study was to examine these findings and to reproduce them in the head and neck area...
  53. Kim H, Yoo Y, Park K, Kwon J, Kim J, Monzon F. Genomic aberrations in salivary duct carcinoma arising in Warthin tumor of parotid gland: DNA microarray and HER2 fluorescence in situ hybridization. Arch Pathol Lab Med. 2011;135:1088-91 pubmed publisher
    ..To our knowledge, this is the first case of salivary duct carcinoma arising from Warthin tumor. The essential molecular pathway has not been reported, we presume an important role of MDM2 amplification- P53 inactivation...