chemoradiotherapy

Summary

Summary: Treatment that combines chemotherapy with radiotherapy.

Top Publications

  1. Raber Durlacher J, Brennan M, Verdonck de Leeuw I, Gibson R, Eilers J, Waltimo T, et al. Swallowing dysfunction in cancer patients. Support Care Cancer. 2012;20:433-43 pubmed publisher
    ..More prospective studies on the course of dysphagia and impact on quality of life from baseline to long-term follow-up after various treatment modalities, including targeted therapies, are needed. ..
  2. Yao J, Yu X, Zhang F, Zhang W, Zhou G, Tang L, et al. Radiotherapy with neoadjuvant chemotherapy versus concurrent chemoradiotherapy for ascending-type nasopharyngeal carcinoma: a retrospective comparison of toxicity and prognosis. Chin J Cancer. 2017;36:26 pubmed publisher
    ..study was to compare the efficacy of NACT followed by IMRT (NACT + RT) with the efficacy of concurrent chemoradiotherapy (CCRT) on ascending-type NPC...
  3. Greuter M, Schouten C, Castelijns J, de Graaf P, Comans E, Hoekstra O, et al. Cost-effectiveness of response evaluation after chemoradiation in patients with advanced oropharyngeal cancer using 18F-FDG-PET-CT and/or diffusion-weighted MRI. BMC Cancer. 2017;17:256 pubmed publisher
    ..However, if healthcare resources are limited, DW-MRI is the strategy of choice because of lower costs while still providing a large reduction in unnecessary EUA indications. ..
  4. Yu Y, Yue J, Yu J. [Value of functional magnetic resonance imaging in predicting outcomes of neoadjuvant chemoradiotherapy in rectal cancer]. Zhonghua Wei Chang Wai Ke Za Zhi. 2017;20:491-494 pubmed
    ..Accurate prediction of the treatment response after the neoadjuvant chemoradiotherapy (CRT) can guide more suitable treatment strategy...
  5. Faivre Finn C. Dose escalation in lung cancer: have we gone full circle?. Lancet Oncol. 2015;16:125-7 pubmed publisher
  6. Amsbaugh M, Yusuf M, Gaskins J, Burton E, Woo S. Patterns of care and predictors of adjuvant therapies in elderly patients with glioblastoma: An analysis of the National Cancer Data Base. Cancer. 2017;123:3277-3284 pubmed publisher
    ..Combined-modality treatment produces improved survival outcomes and should be considered as adjuvant treatment for carefully selected elderly patients. Cancer 2017;123:3277-84. © 2017 American Cancer Society. ..
  7. Kanao H, Aoki Y, Hisa T, Takeshima N. Total laparoscopic pelvic exenteration for a laterally recurrent cervical carcinoma with a vesicovaginal fistula that developed after concurrent chemoradiotherapy. Gynecol Oncol. 2017;146:438-439 pubmed publisher
    For locally advanced cervical carcinoma, concurrent chemoradiotherapy (CCRT) is the standard treatment, however, CCRT can lead to development of a vesicovaginal or rectovaginal fistula [1]...
  8. Torgeson A, Lloyd S, Boothe D, Tao R, Whisenant J, Garrido Laguna I, et al. Multiagent induction chemotherapy followed by chemoradiation is associated with improved survival in locally advanced pancreatic cancer. Cancer. 2017;123:3816-3824 pubmed publisher
    The role of chemoradiotherapy (CRT) in locally advanced pancreatic cancer (LAPC) is uncertain after multiple randomized clinical trials have yielded mixed results...
  9. Liu Y, Zhao G, Xu Y, He X, Li X, Chen H, et al. Multicenter Phase 2 Study of Peri-Irradiation Chemotherapy Plus Intensity Modulated Radiation Therapy With Concurrent Weekly Docetaxel for Inoperable or Medically Unresectable Nonmetastatic Gastric Cancer. Int J Radiat Oncol Biol Phys. 2017;98:1096-1105 pubmed publisher
    ..Common grade 3/4 toxicities during CCRT were nausea and vomiting. This regimen is tolerable and shows promising efficacy in inoperable or medically unresectable GC. ..

More Information

Publications108 found, 100 shown here

  1. Sangkittipaiboon S. Long-term outcomes of concurrent chemoradiotherapy with weekly carboplatin in locally-advanced carcinoma of the uterine cervix patients. J Med Assoc Thai. 2014;97:12-9 pubmed
    To study the treatment outcomes of concurrent chemoradiotherapy with weekly carboplatin in locally-advanced carcinoma of the uterine cervix patients and the complications resulting from the treatment...
  2. Alterio D, Cossu Rocca M, Russell Edu W, Dicuonzo S, Fanetti G, Marvaso G, et al. Feasibility of concurrent chemoradiotherapy with high-dose cisplatin after induction TPF chemotherapy in head and neck cancer: a critical review of the literature and the experience of the European Institute of Oncology. Med Oncol. 2017;34:86 pubmed publisher
    ..cisplatin, 5-fluorouracil) could reduce the ability to deliver the subsequent standard concurrent chemoradiotherapy (CRT) in head and neck cancer patients...
  3. Lester S, Lin S, Chuong M, Bhooshan N, Liao Z, Arnett A, et al. A Multi-institutional Analysis of Trimodality Therapy for Esophageal Cancer in Elderly Patients. Int J Radiat Oncol Biol Phys. 2017;98:820-828 pubmed publisher
    ..For appropriately selected elderly patients, trimodality therapy for esophageal cancer is a reasonable treatment option. ..
  4. Jacinto J, Co J, Mejia M, Regala E. The evidence on effectiveness of weekly vs triweekly cisplatin concurrent with radiotherapy in locally advanced head and neck squamous cell carcinoma (HNSCC): a systematic review and meta-analysis. Br J Radiol. 2017;90:20170442 pubmed publisher
  5. Liu H, Chen Q, Guo L, Tang L, Mo H, Zhong Z, et al. Feasibility and efficacy of chemoradiotherapy for elderly patients with locoregionally advanced nasopharyngeal carcinoma: results from a matched cohort analysis. Radiat Oncol. 2013;8:70 pubmed publisher
    To clarify the feasibility and efficacy of chemoradiotherapy (CRT) in elderly (age?65 years) patients with locoregionally advanced nasopharyngeal carcinoma (NPC)...
  6. Trifiletti D, Smith A, Mitra N, Grover S, Lukens J, Cohen R, et al. Beyond Positive Margins and Extracapsular Extension: Evaluating the Utilization and Clinical Impact of Postoperative Chemoradiotherapy in Resected Locally Advanced Head and Neck Cancer. J Clin Oncol. 2017;35:1550-1560 pubmed publisher
    Purpose To examine recent utilization and survival outcomes associated with use of adjuvant chemoradiotherapy (CRT) for patients with resected locally advanced head and neck cancer (LAHNC) with negative surgical margins (SM negative) and ..
  7. Zhang Y, Sun Y, Xu Z, Chi P, Lu X. Is neoadjuvant chemoradiotherapy always necessary for mid/high local advanced rectal cancer: A comparative analysis after propensity score matching. Eur J Surg Oncol. 2017;43:1440-1446 pubmed publisher
    ..and oncological outcomes of mid/high locally advanced midrectal cancer (LARC) treated with neoadjuvant chemoradiotherapy (NCRT) vs. surgery alone, and to identify risk factors for local recurrence in mid/high LARC...
  8. Sung S, Kim S, Lee J, Nam T, Jeong S, Jang H, et al. Continuous Effect of Radial Resection Margin on Recurrence and Survival in Rectal Cancer Patients Who Receive Preoperative Chemoradiation and Curative Surgery: A Multicenter Retrospective Analysis. Int J Radiat Oncol Biol Phys. 2017;98:647-653 pubmed publisher
    ..proper length and prognostic value of resection margins in rectal cancer patients who received preoperative chemoradiotherapy (CRT) followed by curative total mesorectal excision (TME)...
  9. Paulikova S, Petera J, Sirak I, Vosmik M, Drastíková M, Dusek L, et al. ATM and TGFB1 genes polymorphisms in prediction of late complications of chemoradiotherapy in patients with locally advanced cervical cancer. Neoplasma. 2014;61:70-6 pubmed
    ..to evaluate a possible correlation between genetic polymorphisms in ATM and TGFB1 genes and late toxicity of chemoradiotherapy for locally advanced cervical cancer...
  10. Jakubowicz J, Blecharz P, Skotnicki P, Reinfuss M, Walasek T, Luczyńska E. Toxicity of concurrent chemoradiotherapy for locally advanced cervical cancer. Eur J Gynaecol Oncol. 2014;35:393-9 pubmed
    The analysis of acute and late toxicity of concurrent chemoradiotherapy (CCRT) for locally advanced cervical cancer (LACC) based on review of 120 patients treated in Centre of Oncology in Krakow between 2001 and 2007...
  11. Schrag D. Optimizing Treatment for Locally Advanced Pancreas Cancer: Progress but No Precision. JAMA. 2016;315:1837-8 pubmed publisher
  12. Tyc Szczepaniak D, Wyrwicz L, Wiśniowska K, Michalski W, Pietrzak L, Bujko K. Palliative radiotherapy and chemotherapy instead of surgery in symptomatic rectal cancer with synchronous unresectable metastases: long-term results of a phase II study. Acta Oncol. 2016;55:1369-1370 pubmed
  13. Franco P, Martini S, DI Muzio J, Cavallin C, Arcadipane F, Rampino M, et al. Prospective assessment of oral mucositis and its impact on quality of life and patient-reported outcomes during radiotherapy for head and neck cancer. Med Oncol. 2017;34:81 pubmed publisher
    ..In the present study, we provided a quantitative assessment of OM, PROs and QoL in HNC patient undergoing radiotherapy, potentially useful for future comparison. ..
  14. Martin R. Multi-disciplinary management of locally advanced pancreatic cancer with irreversible electroporation. J Surg Oncol. 2017;116:35-45 pubmed publisher
    ..This review will present the current status of initial chemotherapy, surgical therapy, ablative therapy, and radiation therapy for patients with nonmetastatic locally advanced unresectable pancreatic cancer. ..
  15. Matsuo K, Shimada M, Aoki Y, Sakamoto M, Takeshima N, Fujiwara H, et al. Comparison of adjuvant therapy for node-positive clinical stage IB-IIB cervical cancer: Systemic chemotherapy versus pelvic irradiation. Int J Cancer. 2017;141:1042-1051 pubmed publisher
    ..compared based upon the adjuvant treatment pattern: whole pelvic radiotherapy alone (n?=?253), concurrent chemoradiotherapy (CCRT, n?=?502) and chemotherapy alone (n?=?319)...
  16. Knox J, Cleary S, Dawson L. Localized and systemic approaches to treating hepatocellular carcinoma. J Clin Oncol. 2015;33:1835-44 pubmed publisher
  17. Lynn P, Renfro L, Carrero X, Shi Q, Strombom P, Chow O, et al. Anorectal Function and Quality of Life in Patients With Early Stage Rectal Cancer Treated With Chemoradiation and Local Excision. Dis Colon Rectum. 2017;60:459-468 pubmed publisher
    ..Overall quality of life remained stable, with mixed effects on different subscales. This information should be used to counsel patients about expected outcomes. ..
  18. Macy M, Kieran M, Chi S, Cohen K, Macdonald T, Smith A, et al. A pediatric trial of radiation/cetuximab followed by irinotecan/cetuximab in newly diagnosed diffuse pontine gliomas and high-grade astrocytomas: A Pediatric Oncology Experimental Therapeutics Investigators' Consortium study. Pediatr Blood Cancer. 2017;64: pubmed publisher
    ..While the trial met the predetermined endpoint for DIPG, overall survival was not markedly improved from historical controls, therefore does not merit further study in this population. ..
  19. Yao H, Liu Y. [Diagnosis and treatment strategy for clinical complete responders after chemoradiotherapy for rectal cancer: is watch-and-wait policy safe?]. Zhonghua Wai Ke Za Zhi. 2017;55:496-499 pubmed publisher
    Neo-adjuvant chemoradiotherapy (NACRT) combined with total mesorectal excision (TME) surgery is the main treatment for locally advanced middle-low rectal cancer, and NACRT significantly improves the local control rate of rectal cancer...
  20. Zhang W, Li H, Chen X, Su M, Lin R, Zou C. Phase II study of concurrent chemoradiotherapy with a modified target volumes delineation method for inoperable oesophagealcancer patients. Br J Radiol. 2017;90:20170328 pubmed publisher
    A Phase II study was designed to test the safety and efficacy of concurrent chemoradiotherapy with a modified target volumes delineation method for inoperable oesophageal cancer patients...
  21. Jiang C, Yang P, Lei J, Li J, Yan K, Li F, et al. The Application of Iodine Quantitative Information Obtained by Dual-Source Dual-Energy Computed Tomography on Chemoradiotherapy Effect Monitoring for Cervical Cancer: A Preliminary Study. J Comput Assist Tomogr. 2017;41:737-745 pubmed publisher
    ..of the iodine quantitative parameters of dual-phase dual-energy computed tomography (DECT) scanning for chemoradiotherapy (CRT) response monitoring for cervical cancer...
  22. Naik K, Liu Y, Goodman M, Gillespie T, Pickens A, Force S, et al. Concurrent chemoradiotherapy with or without surgery for patients with resectable esophageal cancer: An analysis of the National Cancer Data Base. Cancer. 2017;123:3476-3485 pubmed publisher
    Patients with resectable esophageal cancer (rEC) are managed with either concurrent chemoradiotherapy followed by surgery (CRSx) or concurrent chemoradiotherapy alone (cCR)...
  23. Jäger T, Neureiter D, Urbas R, Klieser E, Hitzl W, Emmanuel K, et al. Applicability of American Joint Committee on Cancer and College of American Pathologists Regression Grading System in Rectal Cancer. Dis Colon Rectum. 2017;60:815-826 pubmed publisher
    ..have been proposed to predict the association between tumor response and clinical outcome after preoperative chemoradiotherapy in patients with rectal cancer...
  24. de Geus S, Eskander M, Kasumova G, Ng S, Kent T, Mancias J, et al. Stereotactic body radiotherapy for unresected pancreatic cancer: A nationwide review. Cancer. 2017;123:4158-4167 pubmed publisher
    ..These results support the idea that SBRT is a promising treatment approach for patients with unresected pancreatic cancer. Cancer 2017;123:4158-4167. © 2017 American Cancer Society. ..
  25. Merx K, Martens U, Kripp M, Hoehler T, Geissler M, Gaiser T, et al. Panitumumab in Combination With Preoperative Radiation Therapy in Patients With Locally Advanced RAS Wild-type Rectal Cancer: Results of the Multicenter Explorative Single-Arm Phase 2 Study NEORIT. Int J Radiat Oncol Biol Phys. 2017;99:867-875 pubmed publisher
    ..Panitumumab in combination with radiation therapy as neoadjuvant treatment for locally advanced rectal cancer showed a favorable toxicity profile but failed to meet the predefined pCR rate to justify further clinical trials. ..
  26. Ogino I, Watanabe S, Sakamaki K, Ogino Y, Kunisaki C, Kimura K. Dosimetric predictors of radiation-induced pericardial effusion in esophageal cancer. Strahlenther Onkol. 2017;193:552-560 pubmed publisher
    ..pericardial effusion (PE) and symptomatic PE (SPE) in esophageal cancer patients treated with concurrent chemoradiotherapy. In 86 of 303 esophageal cancer patients, follow-up CT was obtained at least 24 months after concurrent ..
  27. Zhang D, Zhan T, Li M, Gu J. [Predictive value of serum carcinoembryonic antigen level in efficacy and prognosis for patients with rectal cancer following preoperative radiochemotherapy]. Zhonghua Wei Chang Wai Ke Za Zhi. 2017;20:519-523 pubmed
    ..However, the prognosis of patients with high CEA level is worse. Recurrence and metastasis are more likely to occur in patients with high CEA level after radiochemotherapy. ..
  28. Tam K, Jeffery C, Sung C. Surgical Management of Supraglottic Stenosis Using Intubationless Optiflow. Ann Otol Rhinol Laryngol. 2017;126:669-672 pubmed publisher
    ..Optiflow is an important new tool in the management of severe supraglottic stenosis. It provides sufficient oxygenation to perform extended apneic surgery and improves endoscopic surgical access in a limited airway. ..
  29. Casiraghi M, Maisonneuve P, Piperno G, Bellini R, Brambilla D, Petrella F, et al. Salvage Surgery After Definitive Chemoradiotherapy for Non-small Cell Lung Cancer. Semin Thorac Cardiovasc Surg. 2017;29:233-241 pubmed publisher
    ..We aimed to evaluate the feasibility of salvage surgery after definitive chemoradiotherapy and perioperative morbidity and mortality rates to determine long-term survival...
  30. Ang K, Zhang Q, Rosenthal D, Nguyen Tan P, Sherman E, Weber R, et al. Randomized phase III trial of concurrent accelerated radiation plus cisplatin with or without cetuximab for stage III to IV head and neck carcinoma: RTOG 0522. J Clin Oncol. 2014;32:2940-50 pubmed
    ..Adding cetuximab to radiation-cisplatin did not improve outcome and hence should not be prescribed routinely. PFS and OS were higher in patients with p16-positive OPC, but outcomes did not differ by EGFR expression. ..
  31. Plana J, Galderisi M, Barac A, Ewer M, Ky B, Scherrer Crosbie M, et al. Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2014;27:911-39 pubmed publisher
  32. Sadahiro S, Suzuki T, Tanaka A, Okada K, Saito G, Miyakita H, et al. Gene expression levels of gamma-glutamyl hydrolase in tumor tissues may be a useful biomarker for the proper use of S-1 and tegafur-uracil/leucovorin in preoperative chemoradiotherapy for patients with rectal cancer. Cancer Chemother Pharmacol. 2017;79:1077-1085 pubmed publisher
    Preoperative chemoradiotherapy (CRT) using 5-fluorouracil (5-FU)-based chemotherapy is the standard of care for rectal cancer...
  33. Nishimura G, Shiono O, Sano D, Yabuki K, Arai Y, Chiba Y, et al. Efficacy and safety of postoperative bio-chemoradiotherapy using cetuximab and docetaxel for high-risk head and neck cancer patients in Japan. Cancer Chemother Pharmacol. 2017;80:203-207 pubmed publisher
    ..With the safety of this treatment confirmed, we propose a phase trail to further clarify the efficacy of cetuximab and docetaxel use for high-risk cisplatin-intolerant patients. ..
  34. Xue Z, Wu F, Pierson K, Mara K, Yang P, Roden A, et al. Survival in Surgical and Nonsurgical Patients With Superior Sulcus Tumors. Ann Thorac Surg. 2017;104:988-997 pubmed publisher
    Treatments for superior sulcus tumor (SST) have evolved, with induction chemoradiotherapy providing an improved R0 resection rate...
  35. Jing Z, Chen T, Zhang X, Wu S. Long-term outcome of concurrent chemoradiotherapy with elective nodal irradiation for inoperable esophageal cancer. Cancer Sci. 2017;108:1828-1833 pubmed publisher
    ..Concurrent chemoradiotherapy with ENI improves both disease-specific overall survival and loco-regional control in patients with ..
  36. Yeom S, Park I, Jung S, Oh S, Lee J, Yoon Y, et al. Outcomes of patients with abdominoperineal resection (APR) and low anterior resection (LAR) who had very low rectal cancer. Medicine (Baltimore). 2017;96:e8249 pubmed publisher
    ..5% vs 55.4%, P?=?.049) and advanced-stage patients (P?<?.001). Preoperative chemoradiotherapy (PCRT) was more frequently administered in the SSR group (83.8% vs 52.8%, P?<?.001)...
  37. Wang Q, Ma J, Lu Y, Zhang S, Huang J, Bei J, et al. CDK20 interacts with KEAP1 to activate NRF2 and promotes radiochemoresistance in lung cancer cells. Oncogene. 2017;36:5321-5330 pubmed publisher
    ..Collectively, our results suggest that CDK20 positively modulate the KEAP1-NRF2 cytoprotective pathway to regulate tumor progression and radiochemoresistance, implying that CDK20 is a novel, promising therapeutic target for lung cancer. ..
  38. Crosby T, Hurt C, Falk S, Gollins S, Staffurth J, Ray R, et al. Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/- cetuximab in oesophageal cancer. Br J Cancer. 2017;116:709-716 pubmed publisher
    The SCOPE-1 study tested the role of adding cetuximab to conventional definitive chemoradiotherapy (dCRT), and demonstrated greater toxicity and worse survival outcomes. We present the long-term outcomes and patterns of recurrence...
  39. Masago K, Fujita S, Hata A, Okuda C, Kaji R, Katakami N, et al. PD-L1 Expression in Patients with Non-small Cell Lung Cancer. Anticancer Res. 2017;37:2269-2274 pubmed
    ..Seventeen patients with NSCLC who received chemoradiotherapy and underwent tumor resection and six patients whose pre-treatment biopsy specimens were available, were ..
  40. de Azevedo C, Thuler L, de Mello M, de Oliveira Lima J, da Fonte A, Fontão D, et al. Phase II trial of neoadjuvant chemotherapy followed by chemoradiation in locally advanced cervical cancer. Gynecol Oncol. 2017;146:560-565 pubmed publisher
    ..4-98.0) and 71.3% (IC 53.3-83.3), respectively. In our hands NACT in locally advanced cervical cancer patients did not show a meaningful improvement in ORR. Nevertheless, we believe it should be further explored in prospective trials. ..
  41. Lattanzio L, Denaro N, Vivenza D, Varamo C, Strola G, Fortunato M, et al. Elevated basal antibody-dependent cell-mediated cytotoxicity (ADCC) and high epidermal growth factor receptor (EGFR) expression predict favourable outcome in patients with locally advanced head and neck cancer treated with cetuximab and radiotherapy. Cancer Immunol Immunother. 2017;66:573-579 pubmed publisher
    ..02). In this study, patients treated with cetuximab and radiotherapy, showing high baseline of both ADCC and EGFR3+, have significant higher probability of achieving a complete response and a long overall survival compared to the others. ..
  42. Kokuryo D, Aoki I, Yuba E, Kono K, Aoshima S, Kershaw J, et al. Evaluation of a combination tumor treatment using thermo-triggered liposomal drug delivery and carbon ion irradiation. Transl Res. 2017;185:24-33 pubmed publisher
    ..The proposed strategy of combining high-LET irradiation and the nanodevice provides an effective approach for minimally invasive cancer treatment. ..
  43. Yamashita H, Seto Y, Takenaka R, Okuma K, Kiritooshi T, Mori K, et al. Survival comparison between radical surgery and definitive chemoradiation in 267 esophageal squamous cell carcinomas in a single institution: A propensity-matched study. PLoS ONE. 2017;12:e0177133 pubmed publisher
    ..A prospective randomized clinical trial will be necessary to draw a definite conclusion. ..
  44. Kuo D, Chang M, Wang S, Hsieh P, Shueng P. Unusual axillary metastasis of recurrent nasopharyngeal cancer: A case report. Medicine (Baltimore). 2017;96:e6854 pubmed publisher
    ..We hereby present the case of a 66-year-old man with NPC, cT2N2M0, at diagnosis. He had completed chemoradiotherapy and been disease-free for 7 years...
  45. Qin Q, Huang B, Cao W, Zhou J, Ma T, Zhou Z, et al. Bowel Dysfunction After Low Anterior Resection With Neoadjuvant Chemoradiotherapy or Chemotherapy Alone for Rectal Cancer: A Cross-Sectional Study from China. Dis Colon Rectum. 2017;60:697-705 pubmed publisher
    ..The study was conducted at a tertiary GI hospital in China. Included patients underwent neoadjuvant chemoradiotherapy or chemotherapy without radiation and curative low anterior resection for rectal cancer between 2012 and ..
  46. Rao Y, Chin R, Hui C, Mutch D, Powell M, Schwarz J, et al. Improved survival with definitive chemoradiation compared to definitive radiation alone in squamous cell carcinoma of the vulva: A review of the National Cancer Database. Gynecol Oncol. 2017;146:572-579 pubmed publisher
    ..These findings suggest that concurrent chemoradiation may be beneficial for select patients in the definitive setting. ..
  47. Fujimoto Y, Nakashima Y, Sasaki S, Jogo T, Hirose K, Edahiro K, et al. Chemoradiotherapy for Solitary Skeletal Muscle Metastasis from Oesophageal Cancer: Case Report and Brief Literature Review. Anticancer Res. 2017;37:5687-5691 pubmed
    ..The incidence of skeletal muscle metastasis from oesophageal cancer is very low, and the treatment strategy has not been established...
  48. Baucom R, Maguire L, Kavalukas S, Geiger T, Ford M, Muldoon R, et al. Nodal Disease in Rectal Cancer Patients With Complete Tumor Response After Neoadjuvant Chemoradiation: Danger Below Calm Waters. Dis Colon Rectum. 2017;60:1260-1266 pubmed publisher
    ..Complete nodal response is not universal in these patients and is difficult to assess clinically. Quantifying the risk of nodal disease would allow for targeted therapy with either radical resection or "watchful waiting."..
  49. Holdhoff M, Rosner G, Alcorn S, Grossman S. 'Elderly' patients with newly diagnosed glioblastoma deserve optimal care. J Neurooncol. 2013;113:343-4 pubmed publisher
  50. Colombo N, Preti E, Landoni F, Carinelli S, Colombo A, Marini C, et al. Endometrial cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013;24 Suppl 6:vi33-8 pubmed publisher
  51. Chang J, Kestin L, Barriger R, Chetty I, Ginsburg M, Kumar S, et al. ACR Appropriateness Criteria® nonsurgical treatment for locally advanced non-small-cell lung cancer: good performance status/definitive intent. Oncology (Williston Park). 2014;28:706-10, 712, 714 passim pubmed
    ..In instances in which evidence is lacking or not definitive, expert opinion may be used as the basis for recommending imaging or treatment. ..
  52. Wang Y, Chen G. Identifying pretreatment baseline factors predictive of distant metastasis in patients with nasopharyngeal carcinoma after radiotherapy. Medicine (Baltimore). 2017;96:e6692 pubmed publisher
    ..A cohort of 119 NPC patients undergoing radiotherapy (RT) or chemoradiotherapy (CRT) were recruited into the study...
  53. Steen R, Dahl A, Hess S, Kiserud C. A study of chronic fatigue in Norwegian cervical cancer survivors. Gynecol Oncol. 2017;146:630-635 pubmed publisher
    ..Some of the associated factors are amenable to prevention and/or treatment and should be subjects of attention at follow-up. ..
  54. Walker A, Kartsonaki C, Collantes E, Nicholson J, Gilbert D, Kiltie A. No additional prognostic value for MRE11 in squamous cell carcinomas of the anus treated with chemo-radiotherapy. Br J Cancer. 2017;117:322-325 pubmed publisher
    ..Further investigation into the role of DNA repair proteins in anal cancer is required. ..
  55. Brackstone M, Palma D, Tuck A, Scott L, Potvin K, Vandenberg T, et al. Concurrent Neoadjuvant Chemotherapy and Radiation Therapy in Locally Advanced Breast Cancer. Int J Radiat Oncol Biol Phys. 2017;99:769-776 pubmed publisher
  56. Van Poppel H, Watkin N, Osanto S, Moonen L, Horwich A, Kataja V. Penile cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2013;24 Suppl 6:vi115-24 pubmed publisher
  57. Niu G, Chen X. RGD PET: From Lesion Detection to Therapy Response Monitoring. J Nucl Med. 2016;57:501-2 pubmed publisher
  58. Silvestris N, Brunetti O, Vasile E, Cellini F, Cataldo I, Pusceddu V, et al. Multimodal treatment of resectable pancreatic ductal adenocarcinoma. Crit Rev Oncol Hematol. 2017;111:152-165 pubmed publisher
    ..latter aiming to reduce the incidence of both distant metastases (chemotherapy) and locoregional failures (chemoradiotherapy)...
  59. Joo J, Shin H, Park B, Park S, Yoo C, Yoon K, et al. Integration Pattern of Human Papillomavirus Is a Strong Prognostic Factor for Disease-Free Survival After Radiation Therapy in Cervical Cancer Patients. Int J Radiat Oncol Biol Phys. 2017;98:654-661 pubmed publisher
    ..This finding may open the possibility of personalized treatment of these patients. ..
  60. Kwon O, Hong S, Kwon S, Go Y, Oh E, Cha H. BCL2 induced by LAMTOR3/MAPK is a druggable target of chemoradioresistance in mesenchymal lung cancer. Cancer Lett. 2017;403:48-58 pubmed publisher
    ..MEK1/MP1/ERK1 axis using a MEK1 inhibitor or MP1 depletion repressed BCL2 expression and sensitized MLCCs to chemoradiotherapy. Taken together, our results suggest that targeting druggable proteins in the MEK1/MP1/ERK1/BCL2 axis, such ..
  61. Chera B, Fried D, Price A, Amdur R, Mendenhall W, Lu C, et al. Dosimetric Predictors of Patient-Reported Xerostomia and Dysphagia With Deintensified Chemoradiation Therapy for HPV-Associated Oropharyngeal Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2017;98:1022-1027 pubmed publisher
    ..After deintensified CRT, the rate of patient-reported xerostomia/dysphagia appears to be associated with the V15 of the combined contralateral salivary glands and V55 to V60 of the superior pharyngeal constrictors. ..
  62. Al Mousa A, Abu Hijlih R, Salem A, Sultan I, Mula Hussain L, Ismael T, et al. Induction Methotrexate, Cisplatin, and 5-Fluorouracil Versus Cisplatin and 5-Fluorouracil Followed by Radiotherapy in Pediatric Nasopharyngeal Carcinoma: A Retrospective Analysis in a Tertiary Cancer Center. J Pediatr Hematol Oncol. 2017;39:e437-e442 pubmed publisher
    ..5-fluorouracil (MPF) or cisplatin and 5-fluorouracil (PF) in pediatric NPC patients treated with sequential chemoradiotherapy. A total of 25 patients aged 18 years or below with stage II-IV NPC treated with IC using PF (n=16) or MPF (..
  63. Boysen A, Wettergren Y, Sorensen B, Taflin H, Gustavson B, Spindler K. Cell-free DNA levels and correlation to stage and outcome following treatment of locally advanced rectal cancer. Tumour Biol. 2017;39:1010428317730976 pubmed publisher
    ..Furthermore, we have found a trend towards a correlation with the risk of recurrence following resection of localized rectal cancer...
  64. Bote H, Alaoui A, Oussama Z, Sayegh H, Iken A, Benslimane L, et al. [Neuroendocrine carcinoma of the bladder: about 5 cases]. Pan Afr Med J. 2017;26:92 pubmed publisher
    ..In one case, cystectomy was performed followed by neoadjuvant chemotherapy; chemoradiotherapy was performed in two cases and palliative chemotherapy in the other two cases...
  65. Chen Y, Chen L, Li W, Lee A, Vermorken J, Wee J, et al. Reporting Quality of Randomized, Controlled Trials Evaluating Combined Chemoradiotherapy in Nasopharyngeal Carcinoma. Int J Radiat Oncol Biol Phys. 2017;98:170-176 pubmed publisher
    ..and EMBASE for RCTs published between January 1988 and December 2015 that assessed the effect of combined chemoradiotherapy for NPC...
  66. Lin W, Ding Y, Hsu H, Chang J, Yuan K, Wu A, et al. Value and application of trimodality therapy or definitive concurrent chemoradiotherapy in thoracic esophageal squamous cell carcinoma. Cancer. 2017;123:3904-3915 pubmed publisher
    Few large, prospective, randomized studies have investigated the value and optimal application of neoadjuvant chemoradiotherapy followed by surgery (trimodality therapy) or definitive concurrent chemoradiotherapy (CCRT) for patients with ..
  67. Sekhar H, Zwahlen M, Trelle S, Malcomson L, Kochhar R, Saunders M, et al. Nodal stage migration and prognosis in anal cancer: a systematic review, meta-regression, and simulation study. Lancet Oncol. 2017;18:1348-1359 pubmed publisher
    ..Studies were eligible if patients received chemoradiotherapy or radiotherapy as the main treatment, reported LNP proportions (all studies), and reported overall survival ..
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