Research Topics | antibiotic prophylaxisSummarySummary: Use of antibiotics before, during, or after a diagnostic, therapeutic, or surgical procedure to prevent infectious complications. Webpages
www.ahrq.gov/research/pedprep/pedchap4.htm ahrq webm&m: case & commentarywebmm.ahrq.gov/case.aspx?caseID=2 nosocomial infectionswww.iph.fgov.be/epidemio/epien/prog7.htm gbsscreen - newborn nursery at lpch - stanford university school of medicinenewborns.stanford.edu/GBSscreen.html special cases to consider - clinical assessment and guidelines | module 1: advanced pain control and sedation | aegdccnmtl.columbia.edu/projects/aegd/mod01_cag_spec.html service delivery guidelines: intrauterine deviceswww.reproline.jhu.edu/english/6read/6multi/sdg/id.htm complications from local anesthesia - advanced techniques and local anesthesia | module 1: advanced pain control and sedation | aegdccnmtl.columbia.edu/projects/aegd/mod01_resources.html search of: cefazolin - list results - clinicaltrials.govclinicaltrials.gov/ct2/results?term=cefazolin bacterial endocarditis and orthodonticswww.rcsed.ac.uk/journal/vol45_3/4530002.htm#THE RISK OF ANTI ... um evidence-based pediatrics web sitewww.med.umich.edu/pediatrics/ebm/topics/cards.htm ol>Research Grants EFFECT OF CRANBERRY CONSTITUENTS ON UTI PATHOGENESISScott J Hultgren; Fiscal Year: 2007 FOCUSJeffrey L Carson; Fiscal Year: 2007 FOCUS Data Coordinating CenterMichael L Terrin; Fiscal Year: 2007 Immunoprotective monoclonals to B. anthracis sporesALISON D O'BRIEN; Fiscal Year: 2003 Peptides surface modification to prevent stent blockageJoseph W Leung; Fiscal Year: 2006 Bacteremia from Dental Extraction vs. Oral HygienePeter B Lockhart; Fiscal Year: 2004 Clinical Trial of Prophylactic Antibiotics for Children*Ron Keren; Fiscal Year: 2007 Clinical Trial of Prophylactic Antibiotics for Children with Vesicoureteral RefluRon Keren; Fiscal Year: 2008 Hemifacial Microsomia: Psychosocial and Other SequelaeMartha M Werler; Fiscal Year: 2008 Hemifacial Microsomia: Psychosocial and Other SequelaeMartha M Werler; Fiscal Year: 2007 ol>Publications [Surgical site infection after total knee arthroplasty: a monocenter analysis of 923 first-intention implantations]R DeBarge Service de Chirurgie Orthopédique et Traumatologique, Centre Albert Trillat, rue Margnolles, 69300 Caluire Rev Chir Orthop Reparatrice Appar Mot 93:582-7 Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing postcesarean infectious morbidity: a randomized, controlled trialScott A Sullivan Department of Obstetrics Gynecology, Medical University of South Carolina, Charleston, SC 29425, USA Am J Obstet Gynecol 196:455.e1-5 Are routine peritoneal fluid cultures during appendicectomy justified?M N Khan Department of General Surgery, North Hampshire Hospital, Basingstoke, UK Ir J Med Sci 176:37-40 [Antibiotic prophylaxis in surgery: news and controversies]Silvano Esposito Clinica Malattie Infettive, Seconda Universita degli Studi di Napoli, Italy Infez Med 10:131-44 Standardized incidence rates of surgical site infection: a multicenter study in ThailandNongyao Kasatpibal Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand Am J Infect Control 33:587-94 [Prophylactic antibiotics in neurosurgery]G Iacob Universitatea de MedicinÄ Åi Farmacie Carol Davila BucureÅti, Facultatea de Medicina, Spitalul Universitar de UrgenÅ£Ä BucureÅti, Clinica de Neurochirurgie Rev Med Chir Soc Med Nat Iasi 111:643-8 Role of perioperative antibiotics in endoscopic skull base surgerySeth M Brown Department of Otorhinolaryngology, Weill Medical College of Cornell University, New York, New York 10021, USA Laryngoscope 117:1528-32 The influence of local instillation of fusidic acid on the development of microbial complications after lung resectionN Baltayiannis Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece J Chemother 18:285-92 [A questionnaire survey on the theory of postoperative infection prophylaxis in urology]Nagao Shinagawa Department of Surgery, Nagoya Midori Municipal Hospital Jpn J Antibiot 55:500-13 [Perioperative antibiotic prophylaxis in transperitoneal tumor nephrectomy: does it lower the rate of clinically significant postoperative infections?]T Steiner ol>Klinik und Poliklinik für Urologie der Friedrich Schiller Universität Jena Urologe A 42:34-7 | Scientific Experts
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Webpages
- pediatric terrorism and disaster preparedness: chapter 4. biological terrorism
www.ahrq.gov/research/pedprep/pedchap4.htm
ahrq webm&m: case & commentarywebmm.ahrq.gov/case.aspx?caseID=2
nosocomial infectionswww.iph.fgov.be/epidemio/epien/prog7.htm
gbsscreen - newborn nursery at lpch - stanford university school of medicinenewborns.stanford.edu/GBSscreen.html
special cases to consider - clinical assessment and guidelines | module 1: advanced pain control and sedation | aegdccnmtl.columbia.edu/projects/aegd/mod01_cag_spec.html
service delivery guidelines: intrauterine deviceswww.reproline.jhu.edu/english/6read/6multi/sdg/id.htm
complications from local anesthesia - advanced techniques and local anesthesia | module 1: advanced pain control and sedation | aegdccnmtl.columbia.edu/projects/aegd/mod01_resources.html
search of: cefazolin - list results - clinicaltrials.govclinicaltrials.gov/ct2/results?term=cefazolin
bacterial endocarditis and orthodonticswww.rcsed.ac.uk/journal/vol45_3/4530002.htm#THE RISK OF ANTI ...
um evidence-based pediatrics web sitewww.med.umich.edu/pediatrics/ebm/topics/cards.htm
channing laboratory - richard platt, mdwww.channing.harvard.edu/platt.htm
bacteroides fragilislib.bioinfo.pl/meid:39151
antrhax - news & journal articles - center for the study of bioterrorism - saint louis university,school of public healthbioterrorism.slu.edu/anthrax/news.htm
publication: antibiotic prophylaxis: update on common clinical useswww.fred.psu.edu/ds/retrieve/fred/publication/8379488
streptococcal infectionslib.bioinfo.pl/meid:17697
urinary tract infection - children - overviewwww.umm.edu/ency/article/000505.htm
qut eprintseprints.qut.edu.au/archive/00005696/
dental care for chronically illbuchta.lib.bioinfo.pl/meid:120215
resources | aegdccnmtl.columbia.edu/projects/aegd/resources.html
a randomized controlled trial on antibiotic prophylaxis in children with vesico-ureteral reflux - full text view - clinicaltrials.govclinicaltrials.gov/ct2/show/NCT00382343
dennis e. niewoehner, md - med - dom - pulmonary allergy sleep med, university of minnesotawww.med.umn.edu/pacc/faculty/niewoehner/home.html
colonoscopy clinical resourcescchs-dl.slis.ua.edu/clinical/gastroenterology/procedures/col ...
the section of epidemiology, anthrax informationwww.epi.hss.state.ak.us/bt/anthrax/anthrax.stm
cidrap >> anthrax decontamination workers should get vaccine or antibiotics, cdc sayswww.cidrap.umn.edu/cidrap/content/bt/anthrax/news/deconwork. ...
gillian sanders's publications - spriesprie.stanford.edu/people/publications/gilliandsanders
the dave project - gastroenterology - atlas of endoscopydave1.mgh.harvard.edu/SearchResults.cfm?criteria=Anna Ruther ...
ada.org: a-z topics: antibiotic prophylaxiswww.ada.org/prof/resources/topics/antibiotic.asp
cdc - epidemiologic responses to anthrax outbreaks: a review of field investigations, 19502001www.cdc.gov/ncidod/eid/vol8no10/02-0223.htm
gillian sanders's publications - fceef.stanford.edu/people/publications/gilliandsanders
ol>Research Grants
EFFECT OF CRANBERRY CONSTITUENTS ON UTI PATHOGENESISScott J Hultgren; Fiscal Year: 2007
..Because of the rise in antibiotic-resistant bacteria and the deleterious effects of long-term antibiotic prophylaxis, alternative therapies for UTIs are needed...
FOCUSJeffrey L Carson; Fiscal Year: 2007
..wrong patient, mislabeling of samples for type and cross match, use of whole blood instead of packed red cells), failure to use thromboembolism prophylaxis, incorrect antibiotic prophylaxis, wrong site surgery and femoral shaft fracture.
FOCUS Data Coordinating CenterMichael L Terrin; Fiscal Year: 2007
..use of whole blood instead of packed red cells), failure to use thromboembolism prophylaxis, incorrect antibiotic prophylaxis, wrong site surgery, and femoral shaft fracture.
..
Immunoprotective monoclonals to B. anthracis sporesALISON D O'BRIEN; Fiscal Year: 2003
..A remaining health concern is that the people who received antibiotic prophylaxis may still present with inhalation anthrax after conclusion of their therapy as dormant viable spores ..
Peptides surface modification to prevent stent blockageJoseph W Leung; Fiscal Year: 2006
..including use of different plastic materials, changing stent designs, biocide impregnation and systemic antibiotic prophylaxis. However, none of these methods have produced significant clinical benefits...
Bacteremia from Dental Extraction vs. Oral HygienePeter B Lockhart; Fiscal Year: 2004
DESCRIPTION: (provided by applicant): The use of antibiotic prophylaxis to prevent distant site infections (DSI) from oral pathogens remains a controversial issue in clinical practice...
Clinical Trial of Prophylactic Antibiotics for Children*Ron Keren; Fiscal Year: 2007
..We will also determine whether antibiotic prophylaxis increases the rate of gastrointestinal (Gl) colonization with antibiotic resistant E...
Clinical Trial of Prophylactic Antibiotics for Children with Vesicoureteral RefluRon Keren; Fiscal Year: 2008
..We will also determine whether antibiotic prophylaxis increases the rate of gastrointestinal (Gl) colonization with antibiotic resistant E...
Hemifacial Microsomia: Psychosocial and Other SequelaeMartha M Werler; Fiscal Year: 2008
..g., orthognathic), treatments (e.g., antibiotic prophylaxis), interventions (e.g., hearing aids), and other speciality consultations...
Hemifacial Microsomia: Psychosocial and Other SequelaeMartha M Werler; Fiscal Year: 2007
..g., orthognathic), treatments (e.g., antibiotic prophylaxis), interventions (e.g., hearing aids), and other speciality consultations...
Targeting protein synthesis in AMLARTHUR FRANKEL; Fiscal Year: 2005
..binding and inducing cytokine release from patient monocytes have occurred, necessitating steroid and antibiotic prophylaxis. Further, some patients failed to show leukemic cytoreductions...
Reservoirs of Antibiotic Resistance--BioinformaticsMichael Feldgarden; Fiscal Year: 2006
..tools and the research activities that they facilitate will have applications in the management of antibiotic prophylaxis and therapy in human disease, animal husbandry and horticulture and in management of genetically modified ..
Reservoirs of Antibiotic Resistance--BioinformaticsKARIN U TRAVERS; Fiscal Year: 2002
..tools and the research activities that they facilitate will have applications in the management of antibiotic prophylaxis and therapy in human disease, animal husbandry and horticulture and in management of genetically modified ..
Primary Vesicoureteral Reflux in ChildrenTej K Mattoo; Fiscal Year: 2007
..Despite the widespread use of antibiotic prophylaxis in children with VUR, there are no placebo-controlled studies demonstrating its clinical benefit in ..
Primary Vesicoureteral Reflux in ChildrenTej K Mattoo; Fiscal Year: 2008
..Despite the widespread use of antibiotic prophylaxis in children with VUR, there are no placebo-controlled studies demonstrating its clinical benefit in ..
Virulence regulation in group B StreptococcusMichael R Wessels; Fiscal Year: 2008
DESCRIPTION (provided by applicant): Despite progress in maternal prenatal screening and peripartum antibiotic prophylaxis, group B Streptococcus (Streptococcus agalactiae or GBS) infection remains a leading cause of neonatal sepsis and ..
Virulence regulation in group B StreptococcusMichael R Wessels; Fiscal Year: 2007
DESCRIPTION (provided by applicant): Despite progress in maternal prenatal screening and peripartum antibiotic prophylaxis, group B Streptococcus (Streptococcus agalactiae or GBS) infection remains a leading cause of neonatal sepsis and ..
CLINICAL STUDY OF VESICOURETERAL REFLUX IN CHILDRENMyra A Carpenter; Fiscal Year: 2008
..Candidate interventions are open surgery, endoscopic surgery, or antibiotic prophylaxis. We propose a randomized, placebo-controlled clinical trial of prophlaxic [sic] antibiotic therapy to ..
CLINICAL STUDY OF VESICOURETERAL REFLUX IN CHILDRENMyra A Carpenter; Fiscal Year: 2007
..Candidate interventions are open surgery, endoscopic surgery, or antibiotic prophylaxis. We propose a randomized, placebo-controlled clinical trial of prophlaxic [sic] antibiotic therapy to ..
POET Study: A Randomized Multi-institutional Clinical Trial of Girls with RefluxSaul P Greenfield; Fiscal Year: 2008
..While long term antibiotic prophylaxis works well in preventing urinary infection, it has been proposed that it may not be necessary in this ..
POET Study: A Randomized Multi-institutional Clinical T*Saul P Greenfield; Fiscal Year: 2007
..While long term antibiotic prophylaxis works well in preventing urinary infection, it has been proposed that it may not be necessary in this ..
CONSEQUENCES OF GROUP B STREPTOCOCCAL PROPHYLAXISAnushua Sinha; Fiscal Year: 2004
..The research builds on Dr. Sinha's NIAID-funded work to investigate the impact of maternal antibiotic prophylaxis against neonatal group B streptococcus on non-GBS infectious outcomes of both infants and mothers...
ol>Publications
[Surgical site infection after total knee arthroplasty: a monocenter analysis of 923 first-intention implantations]R DeBarge
Service de Chirurgie Orthopédique et Traumatologique, Centre Albert Trillat, rue Margnolles, 69300 Caluire
Rev Chir Orthop Reparatrice Appar Mot 93:582-7
Service de Chirurgie Orthopédique et Traumatologique, Centre Albert Trillat, rue Margnolles, 69300 Caluire
Rev Chir Orthop Reparatrice Appar Mot 93:582-7
..Age and body mass index did not differ between patients with and without surgical site infection. CONCLUSION: The analysis of our series demonstrated the difficulties in conducting long-term surveillance...
Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing postcesarean infectious morbidity: a randomized, controlled trialScott A Sullivan
Department of Obstetrics Gynecology, Medical University of South Carolina, Charleston, SC 29425, USA
Am J Obstet Gynecol 196:455.e1-5
Department of Obstetrics Gynecology, Medical University of South Carolina, Charleston, SC 29425, USA
Am J Obstet Gynecol 196:455.e1-5
..This dosing did not result in increased neonatal septic workups or complications...
Are routine peritoneal fluid cultures during appendicectomy justified?M N Khan
Department of General Surgery, North Hampshire Hospital, Basingstoke, UK
Ir J Med Sci 176:37-40
Department of General Surgery, North Hampshire Hospital, Basingstoke, UK
Ir J Med Sci 176:37-40
..7%) were the recorded complications in group II. Antibiotics were modified in 3 out of 109 patients. CONCLUSION: Intra-operative peritoneal cultures during appendicectomy do not significantly contribute towards patient management...
[Antibiotic prophylaxis in surgery: news and controversies]Silvano Esposito
Clinica Malattie Infettive, Seconda Universita degli Studi di Napoli, Italy
Infez Med 10:131-44
Clinica Malattie Infettive, Seconda Universita degli Studi di Napoli, Italy
Infez Med 10:131-44
..adeguate for the situation in question: evidence from several sources would extend the advisability of antibiotic prophylaxis to other clean surgeries; the current classification of surgical procedures does not consider the "..
Standardized incidence rates of surgical site infection: a multicenter study in ThailandNongyao Kasatpibal
Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
Am J Infect Control 33:587-94
Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand
Am J Infect Control 33:587-94
..of this study was to estimate the incidence of SSI in 9 hospitals, together with patterns of surgical antibiotic prophylaxis, risk factors for SSI, and common causative pathogens...
[Prophylactic antibiotics in neurosurgery]G Iacob
Universitatea de MedicinÄ Åi Farmacie Carol Davila BucureÅti, Facultatea de Medicina, Spitalul Universitar de UrgenÅ£Ä BucureÅti, Clinica de Neurochirurgie
Rev Med Chir Soc Med Nat Iasi 111:643-8
Universitatea de MedicinÄ Åi Farmacie Carol Davila BucureÅti, Facultatea de Medicina, Spitalul Universitar de UrgenÅ£Ä BucureÅti, Clinica de Neurochirurgie
Rev Med Chir Soc Med Nat Iasi 111:643-8
..Clinical studies emphasized that the most important factors influencing the choice of antibiotic prophylaxis in neurosurgery is the patient's immune status, virulence of the pathogens and the type of surgery ("..
Role of perioperative antibiotics in endoscopic skull base surgerySeth M Brown
Department of Otorhinolaryngology, Weill Medical College of Cornell University, New York, New York 10021, USA
Laryngoscope 117:1528-32
Department of Otorhinolaryngology, Weill Medical College of Cornell University, New York, New York 10021, USA
Laryngoscope 117:1528-32
..CONCLUSIONS: Despite direct contamination of the intracranial cavity during endoscopic, endonasal skull base surgery, the risk of CNS infections is low. Limited use of a single perioperative antibiotic may be sufficient prophylaxis...
The influence of local instillation of fusidic acid on the development of microbial complications after lung resectionN Baltayiannis
Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece
J Chemother 18:285-92
Department of Thoracic Surgery, Metaxa Cancer Hospital, Piraeus, Greece
J Chemother 18:285-92
..838; P <0.001, respectively). These results indicate that local instillation of fusidic acid in the pleural space prior to lung resection seems effective in reducing the rate of septic complications as well as of wound infections...
[A questionnaire survey on the theory of postoperative infection prophylaxis in urology]Nagao Shinagawa
Department of Surgery, Nagoya Midori Municipal Hospital
Jpn J Antibiot 55:500-13
Department of Surgery, Nagoya Midori Municipal Hospital
Jpn J Antibiot 55:500-13
..The most commonly used agent for clean operations are cefazolin (CEZ), followed by cefotiam (CTM) and piperacillin (PIPC), in this order. For clean-contaminated operations, the most commonly used agent is CTM, followed by PIPC and CEZ...
[Perioperative antibiotic prophylaxis in transperitoneal tumor nephrectomy: does it lower the rate of clinically significant postoperative infections?]T Steiner
Klinik und Poliklinik für Urologie der Friedrich Schiller Universität Jena
Urologe A 42:34-7
Klinik und Poliklinik für Urologie der Friedrich Schiller Universität Jena
Urologe A 42:34-7
..prospective randomized study was designed to determine the efficacy of single-shot perioperative antibiotic prophylaxis with 1 g ceftriaxone i.v. in transperitoneal tumor nephrectomy...
Abdominal surgical site infections: incidence and risk factors at an Iranian teaching hospitalSeyd Mansour Razavi
Community Medicine Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
BMC Surg 5:2
Community Medicine Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
BMC Surg 5:2
....
Vancomycin versus cefazolin prophylaxis for cerebrospinal shunt placement in a hospital with a high prevalence of meticillin-resistant Staphylococcus aureusE Tacconelli
Department of Infectious Diseases, Catholic University, Rome, Italy
J Hosp Infect 69:337-44
Department of Infectious Diseases, Catholic University, Rome, Italy
J Hosp Infect 69:337-44
..02). Our data suggest that use of vancomycin as prophylactic agent for cerebrospinal shunt placement reduces the rate of shunt infections in the context of high prevalence of MRSA...
Perioperative antibiotic prophylaxis: a critical reviewFausto de Lalla
Department of Infectious Diseases, Ospedale S Bortolo, Vicenza, Italy
Surg Infect (Larchmt) 7:S37-9
Department of Infectious Diseases, Ospedale S Bortolo, Vicenza, Italy
Surg Infect (Larchmt) 7:S37-9
..CONCLUSION: Antibiotic prophylaxis is generally overprescribed (i.e., given for too long). Short-duration prophylaxis is effective and safe.
Risk of Clostridium difficile infection after perioperative antibacterial prophylaxis before and during an outbreak of infection due to a hypervirulent strainAlex Carignan
Department of Microbiology and Infectious Diseases, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
Clin Infect Dis 46:1838-43
Department of Microbiology and Infectious Diseases, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, Quebec, Canada
Clin Infect Dis 46:1838-43
..In situations in which the only purpose of PAP is to prevent infrequent and relatively benign infections, the risks may outweigh the benefits in some elderly patients...
Selective antibiotic use to prevent postoperative wound infection after external dacryocystorhinostomyBulent Yazici
Lions Eye Institute, Department of Opthalmology, Albany Medical College, Albany, New York 12208, USA
Ophthal Plast Reconstr Surg 18:331-5; discussion 335
Lions Eye Institute, Department of Opthalmology, Albany Medical College, Albany, New York 12208, USA
Ophthal Plast Reconstr Surg 18:331-5; discussion 335
PURPOSE: The use of systemic antibiotic prophylaxis in lacrimal drainage surgery is controversial...
The Society of Thoracic Surgeons Practice Guideline Series: Antibiotic Prophylaxis in Cardiac Surgery, Part I: DurationFred H Edwards
Division of Cardiothoracic Surgery, University of Florida, Jacksonville, Florida 32209, USA
Ann Thorac Surg 81:397-404
Division of Cardiothoracic Surgery, University of Florida, Jacksonville, Florida 32209, USA
Ann Thorac Surg 81:397-404
Amoxicillin/clavulanic acid versus cefotaxime for antimicrobial prophylaxis in abdominal surgery: a randomized trialF Tonelli
Dipartimento di Fisiopatologia Clinica, Università degli Studi di Firenze, Italy
J Chemother 14:366-72
Dipartimento di Fisiopatologia Clinica, Università degli Studi di Firenze, Italy
J Chemother 14:366-72
..Its use in surgical prophylaxis may help decrease the cost of treatment and reduce the risk of resistance to antibiotics and superinfections...
[Appropriate antibiotic prophylaxis and treatment in surgery--comparison of concepts in North America and Japan]Yoshio Takesue
Department of Surgery, Programs for Applied Biomedicine, Hiroshima University, Hiroshima, Japan
Nippon Geka Gakkai Zasshi 105:709-15
Department of Surgery, Programs for Applied Biomedicine, Hiroshima University, Hiroshima, Japan
Nippon Geka Gakkai Zasshi 105:709-15
..Careful application of these concepts should allow surgeons to use more optimal dosing regimens in Japan...
Infective complications according to duration of antibiotic treatment in acute abdomenAna L M Gleisner
General Surgery Division, Hospital de ClÃnicas de Porto Alegre, Porto Alegre, RS, Brazil
Int J Infect Dis 8:155-62
General Surgery Division, Hospital de ClÃnicas de Porto Alegre, Porto Alegre, RS, Brazil
Int J Infect Dis 8:155-62
..CONCLUSIONS: Shorter courses of antibiotic therapy based on the degree of contamination/infection seem to be safe. A prospective study should confirm this hypothesis...
Prophylactic antibiotic use in oral surgery--a review of current conceptsEphraim Rikhotso
Division of Maxillofacial Surgery, Baragwanath Hospital, University of the Witwatersrand, Johannesburg
SADJ 57:408-13
Division of Maxillofacial Surgery, Baragwanath Hospital, University of the Witwatersrand, Johannesburg
SADJ 57:408-13
Single-dose and multi-dose clindamycin therapy fails to demonstrate efficacy in preventing infectious and inflammatory complications in third molar surgeryT Kaczmarzyk
Department of Oral Surgery, The Medical College of the Jagiellonian University, ul Montelupich 4, 31 155 Krakow, Poland
Int J Oral Maxillofac Surg 36:417-22
Department of Oral Surgery, The Medical College of the Jagiellonian University, ul Montelupich 4, 31 155 Krakow, Poland
Int J Oral Maxillofac Surg 36:417-22
..Clindamycin applied in a single preoperative dose of 600 mg with or without subsequent 5-day therapy does not demonstrate efficacy in prophylaxis for postoperative inflammatory complications after third molar surgery...
Usage of prophylactic antibiotics in uncomplicated gynecologic abdominal surgery in Siriraj hospitalDittakarn Boriboonhirunsarn
Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
J Med Assoc Thai 90:1068-73
Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
J Med Assoc Thai 90:1068-73
..The rate of postoperative infection between control and study groups, as well as between single and other antibiotic prophylaxis were similar...
Influence of broad-spectrum antibiotic prophylaxis on intracranial pressure monitor infections and subsequent infectious complications in head-injured patientsAddison K May
Division of Trauma and Surgical Critical Care, Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN 37212, USA
Surg Infect (Larchmt) 7:409-17
Division of Trauma and Surgical Critical Care, Section of Surgical Sciences, Vanderbilt University Medical Center, Nashville, TN 37212, USA
Surg Infect (Larchmt) 7:409-17
BACKGROUND: The benefit of antibiotic prophylaxis for intracranial pressure (ICP) monitors remains controversial, and clinical practice varies widely...
Assessment of a protocol for prophylactic antibiotics to prevent perioperative infection in urological surgery: a preliminary studySojun Kanamaru
Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Int J Urol 11:355-63
Department of Urology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Int J Urol 11:355-63
..Thus, our protocol of prophylactic antibiotic therapy would be recommended as an appropriate method for preventing perioperative infection in urological surgery...
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trialOrjan Friberg
Department of Cardiothoracic Surgery, Orebro University Hospital, Orebro, Sweden
Ann Thorac Surg 79:153-61; discussion 161-2
Department of Cardiothoracic Surgery, Orebro University Hospital, Orebro, Sweden
Ann Thorac Surg 79:153-61; discussion 161-2
..CONCLUSIONS: Local collagen-gentamicin reduced the risk for postoperative sternal wound infections. Further studies are warranted to confirm these results, particularly with regard to deep infections...
Surveillance of post-operative infections and management of antibiotic surgical prophylaxis in an Italian regionS Esposito
Dipartimento di Malattie Infettive, Seconda Università di Napoli, Italy
J Chemother 16:160-5
Dipartimento di Malattie Infettive, Seconda Università di Napoli, Italy
J Chemother 16:160-5
..length of pre- and post-operative hospitalization, type of surgery, intervention duration, possible antibiotic prophylaxis and onset of post-surgical infections also monitored by post-discharge ambulatory controls...
Ertapenem versus cefotetan prophylaxis in elective colorectal surgeryKamal M F Itani
Veterans Affairs Boston Healthcare System and Boston University Medical School, Boston, MA 02132, USA
N Engl J Med 355:2640-51
Veterans Affairs Boston Healthcare System and Boston University Medical School, Boston, MA 02132, USA
N Engl J Med 355:2640-51
..METHODS: In this randomized, double-blind trial, we assessed the efficacy and safety of antibiotic prophylaxis with ertapenem, as compared with cefotetan, in patients undergoing elective colorectal surgery...
Quality improvement of surgical prophylaxis in Dutch hospitals: evaluation of a multi-site intervention by time series analysisMarjo E E Van Kasteren
Department of Internal Medicine, University Medical Centre Nijmegen, Nijmegen, The Netherlands
J Antimicrob Chemother 56:1094-102
Department of Internal Medicine, University Medical Centre Nijmegen, Nijmegen, The Netherlands
J Antimicrob Chemother 56:1094-102
..4% (95% CI: 4.3-6.5) and 4.6% (95% CI: 3.6-5.4), respectively. CONCLUSIONS: The intervention led to improved quality of surgical prophylaxis and to reduced antibiotic use and costs without impairment of patient outcome...
Role of topical antibiotics in hip surgery. A prospective randomised studyS Kamath
Orthopaedics, Leighton Hospital, Crewe, CW1 4QJ, UK
Injury 36:783-7
Orthopaedics, Leighton Hospital, Crewe, CW1 4QJ, UK
Injury 36:783-7
..However, this was not statistically significant to recommend its use in routine practice. A larger study should provide useful information on the role of topical antibiotic and its effect on postoperative wound infection...
Prophylaxis versus pre-emptive treatment for infective and inflammatory complications of surgical third molar removal: a randomized, double-blind, placebo-controlled, clinical trial with sustained release amoxicillin/clavulanic acid (1000/62.5 mg)J M Lacasa
Service of Internal Medicine, Hospital Mútua de Terrassa, University of Barcelona, Barcelona, Spain
Int J Oral Maxillofac Surg 36:321-7
Service of Internal Medicine, Hospital Mútua de Terrassa, University of Barcelona, Barcelona, Spain
Int J Oral Maxillofac Surg 36:321-7
..Prophylaxis was beneficial in simpler procedures and may be indicated in cases where ostectomy is not performed...
Risk factors for surgical-site infections in head and neck cancer surgeryCarlos Jorge Lotfi
Infectious Diseases Service, Hospital do Câncer A C Camargo, São Paulo, Brazil
Otolaryngol Head Neck Surg 138:74-80
Infectious Diseases Service, Hospital do Câncer A C Camargo, São Paulo, Brazil
Otolaryngol Head Neck Surg 138:74-80
..surgery were those with cancer at advanced stages, those who were smokers, those presenting comorbidities, those who needed major reconstruction of the surgical wound, or those who were submitted to inadequate antibiotic prophylaxis.
A prospective placebo-controlled double-blind trial of antibiotic prophylaxis in intraoral bone grafting procedures: a pilot studyJerome A H Lindeboom
Department of Oral and Maxillofacial Surgery, Academic Medical Center and Academic Center for Dentistry, University of Amsterdam, The Netherlands
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:669-72
Department of Oral and Maxillofacial Surgery, Academic Medical Center and Academic Center for Dentistry, University of Amsterdam, The Netherlands
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 96:669-72
..of a single-dose preoperative prophylactic of the penicillin pheneticillin compared with placebo in the antibiotic prophylaxis of surgical wound infections in intra-oral bone grafting procedures...
Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4,578 patientsA M Korinek
Neuroanaesthesia Unit, Department of Anaesthesiology, Pitié Salpêtrière Hospital, University of Paris VI, Paris, France
Br J Neurosurg 19:155-62
Neuroanaesthesia Unit, Department of Anaesthesiology, Pitié Salpêtrière Hospital, University of Paris VI, Paris, France
Br J Neurosurg 19:155-62
..of this study was to evaluate incidence and risk factors of postoperative infections, with emphasis on antibiotic prophylaxis, in a series of 4578 craniotomies...
Reduction in surgical antibiotic prophylaxis expenditure and the rate of surgical site infection by means of a protocol that controls the use of prophylaxisMarisa I Gomez
Sanatorio Adventista del Plata, Facultad de Ciencias de la Salud de la Universidad Adventista del Plata, Libertador San MartÃn, Entre RÃos, Argentina
Infect Control Hosp Epidemiol 27:1358-65
Sanatorio Adventista del Plata, Facultad de Ciencias de la Salud de la Universidad Adventista del Plata, Libertador San MartÃn, Entre RÃos, Argentina
Infect Control Hosp Epidemiol 27:1358-65
..protocol with an automatic stop of antimicrobial prophylaxis to improve hospital compliance with surgical antibiotic prophylaxis guidelines...
Preventing postoperative Staphylococcus infections: an updateMatthew Grady
Department of Surgery, University of Iowa College of Medicine, and Veterans Affairs Medical Center, Iowa City, IA, USA
Surg Technol Int 11:57-60
Department of Surgery, University of Iowa College of Medicine, and Veterans Affairs Medical Center, Iowa City, IA, USA
Surg Technol Int 11:57-60
..Mupirocin, a topical antibiotic effective against Gram-positive organisms, was proved to be effective in reducing the rates of nasal colonization of S. aureus and decreased postoperative nosocomial infections due to S. aureus...
Post-operative infection following hand surgery. Guidelines for antibiotic useA J Platt
Department of Plastic Surgery, Northern General Hospital, Sheffield, UK
J Hand Surg Br 20:685-90
Department of Plastic Surgery, Northern General Hospital, Sheffield, UK
J Hand Surg Br 20:685-90
..002). A postal questionnaire of members of the British Society for Surgery of the Hand revealed a wide variation in antibiotic usage. Guidelines for antibiotic use in patients undergoing hand surgery are presented...
Recovery of the susceptibility of isolated bacterium achieved by giving long-established antibiotics as prophylaxis against postoperative infectionsShinya Kusachi
Third Department of Surgery, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo 153-8515, Japan
Surg Today 34:725-31
Third Department of Surgery, Toho University School of Medicine, 2-17-6 Ohashi, Meguro-ku, Tokyo 153-8515, Japan
Surg Today 34:725-31
....
Bacteria of preoperative urinary tract infections contaminate the surgical fields and develop surgical site infections in urological operationsRyoichi Hamasuna
Department of Urology, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki, Japan
Int J Urol 11:941-7
Department of Urology, Miyazaki Medical College, University of Miyazaki, Kiyotake, Miyazaki, Japan
Int J Urol 11:941-7
..CONCLUSIONS: Preoperative UTI was the most important risk factor for SSI following urological operations. It is most likely that the bacteria in the urine contaminated the surgical fields and the AMP resistant strains produced SSI...
Antibiotic prophylaxis in colorectal surgeryFrancesca Rovera
Department of Surgical Sciences, University of Insubria, Azienda Ospedaliero Universitaria, Fondazione Macchi, Varese, Italy
Expert Rev Anti Infect Ther 3:787-95
Department of Surgical Sciences, University of Insubria, Azienda Ospedaliero Universitaria, Fondazione Macchi, Varese, Italy
Expert Rev Anti Infect Ther 3:787-95
..It is reported that without antibiotic prophylaxis, wound infection after colorectal surgery develops in approximately 40% of patients...
Factors associated with postoperative infectionJ D Scott
Clinical Pharmacokinetics Laboratory, Millard Fillmore Hospital, Buffalo, New York, USA
Infect Control Hosp Epidemiol 22:347-51
Clinical Pharmacokinetics Laboratory, Millard Fillmore Hospital, Buffalo, New York, USA
Infect Control Hosp Epidemiol 22:347-51
..Interestingly, albumin and age were significantly associated with death within 28 days, in addition to early infection, showing the predictive association between these factors and early death...
Antimicrobial prophylaxis in the surgical patientHarrison G Weed
Division of General Internal Medicine, The Ohio State University College of Medicine, 4510 UHC Cramblett Hall, 456 West 10th Avenue, Columbus, OH 43210, USA
Med Clin North Am 87:59-75
Division of General Internal Medicine, The Ohio State University College of Medicine, 4510 UHC Cramblett Hall, 456 West 10th Avenue, Columbus, OH 43210, USA
Med Clin North Am 87:59-75
..Although we do not have either the randomized, controlled trials or the detailed, patient-specific information to estimate this balance precisely, there are general guidelines to help the clinician choose treatment for most patients...
The practice of perioperative antibiotic prophylaxis in eight German hospitalsM Dettenkofer
Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Germany
Infection 30:164-7
Institute of Environmental Medicine and Hospital Epidemiology, Freiburg University Hospital, Germany
Infection 30:164-7
..Although there is consensus in the international literature on the benefits of using perioperative antibiotic prophylaxis (PAP), there is still considerable scope for improving its use in many hospitals...
Infectious complications and antibiotic use in dermatologic surgeryEva A Hurst
UCSF Dermatologic Surgery and Laser Center, San Francisco, CA 94115, USA
Semin Cutan Med Surg 26:47-53
UCSF Dermatologic Surgery and Laser Center, San Francisco, CA 94115, USA
Semin Cutan Med Surg 26:47-53
..In addition, recommendations surrounding endocarditis and prosthetic joint infection prophylaxis are presented as they apply to dermatologic surgery...
Prevalence and predictors of surgical site infection in Tbilisi, Republic of GeorgiaS Brown
Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
J Hosp Infect 66:160-6
Massachusetts General Hospital Harvard Medical School, Boston, MA, USA
J Hosp Infect 66:160-6
..In a separate model, NNIS risk index was highly predictive of SSI. Antibiotic prophylaxis was rare (29.5% of operations), while postoperative antibiotic use was common...
Intranasal mupirocin to prevent postoperative infectionsChristof von Eiff
N Engl J Med 347:1207-8; author reply 1207-8
N Engl J Med 347:1207-8; author reply 1207-8
Mupirocin to prevent S. aureus infectionsBarry M Farr
N Engl J Med 346:1905-6
N Engl J Med 346:1905-6
Five day antibiotic prophylaxis for major lower limb amputation reduces wound infection rates and the length of in-hospital stayU Sadat
Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
Eur J Vasc Endovasc Surg 35:75-8
Cambridge Vascular Unit, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
Eur J Vasc Endovasc Surg 35:75-8
..77.5% vs. 55% P=0.033). CONCLUSIONS: This data supports the use of a prolonged 5-day course of combined antibiotics after major lower limb amputation. This appears to reduce stump infection rates leading to shorter in-hospital stay...
A randomized, double-blind, placebo-controlled trial to determine effectiveness of antibiotic prophylaxis for tension-free mesh herniorrhaphyAnthony R Perez
Department of Surgery, University of the Philippines College of Medicine and Philippine General Hospital, Manila, Philippines
J Am Coll Surg 200:393-7; discussion 397-8
Department of Surgery, University of the Philippines College of Medicine and Philippine General Hospital, Manila, Philippines
J Am Coll Surg 200:393-7; discussion 397-8
..Our results do not support use of antibiotic prophylaxis for tension-free mesh herniorrhaphy.
Prophylactic antibiotics given within 24 hours of surgery, compared with antibiotics given for 72 hours perioperatively, increased the rate of methicillin-resistant Staphylococcus aureus isolated from surgical site infectionsShinya Kusachi
Third Department of Surgery, Toho University Ohashi Medical Center Hospital, 2 17 6 Ohashi, Meguro ku, Tokyo, Japan
J Infect Chemother 14:44-50
Third Department of Surgery, Toho University Ohashi Medical Center Hospital, 2 17 6 Ohashi, Meguro ku, Tokyo, Japan
J Infect Chemother 14:44-50
..aureus (MSSA) were both significantly higher in period B patients (P < 0.005). We concluded that the administration of prophylactic antibiotics within 24 h of surgery increased the rate of isolation of MRSA...
Comparison of routine prophylaxis with vancomycin or cefazolin for femoral neck fracture surgery: microbiological and clinical outcomesJacques Merrer
Unité de Lutte Contre les Infections Nosocomiales, Hôpital de Poissy St Germain en Laye, Poissy, France
Infect Control Hosp Epidemiol 27:1366-71
Unité de Lutte Contre les Infections Nosocomiales, Hôpital de Poissy St Germain en Laye, Poissy, France
Infect Control Hosp Epidemiol 27:1366-71
OBJECTIVE: To assess the impact of antibiotic prophylaxis on the emergence of vancomycin-resistant strains of Enterococcus faecium, Enterococcus faecalis, and Staphylococcus aureus and the incidence of surgical site infection (SSI) after ..
Prospective randomized comparison of single-dose versus 1-day cefazolin for prophylaxis in gynecologic surgeryHer-Young Su
Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Acta Obstet Gynecol Scand 84:384-9
Department of Obstetrics and Gynecology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Acta Obstet Gynecol Scand 84:384-9
..Shortening the duration of antibiotics prophylaxis also reduced medical costs and microorganism resistance...
Antimicrobial prophylaxis in laparotomic gynecologic surgery: a prospective randomized study comparing amoxicillin-clavulanic acid with cefazolinG Cormio
Sezione di Ginecologia A, Dipartimento di Scienze Chirurgiche Generali e Specialistiche, Università degli Studi di Bari, Italy
J Chemother 14:618-22
Sezione di Ginecologia A, Dipartimento di Scienze Chirurgiche Generali e Specialistiche, Università degli Studi di Bari, Italy
J Chemother 14:618-22
..It is concluded that ultra-short term prophylaxis with both amoxicillin-clavulanic acid and cefazolin is safe and effective in elective laparotomic gynecologic surgery...
Cefazolin versus cefazolin plus metronidazole for antibiotic prophylaxis at cesarean sectionNorman L Meyer
Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, TN 38103 2896, USA
South Med J 96:992-5
Department of Obstetrics and Gynecology, University of Tennessee Health Science Center, Memphis, TN 38103 2896, USA
South Med J 96:992-5
..0064 versus P = 0.014) compared with cefazolin alone. The estimated antibiotic prophylaxis cost per person was less with cefazolin and metronidazole than with cefazolin alone (9...
A pilot study to determine the feasibility of continuous cefazolin infusionTodd Waltrip
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY 40292, USA
Surg Infect (Larchmt) 3:5-9
Price Institute of Surgical Research, University of Louisville School of Medicine, Louisville, KY 40292, USA
Surg Infect (Larchmt) 3:5-9
....
End-of-procedure cefazolin concentrations after administration for prevention of surgical-site infectionErin Koopman
Saint Mary s Hospital, Mayo Clinic, Rochester, MN, USA
Am J Health Syst Pharm 64:1927-34
Saint Mary s Hospital, Mayo Clinic, Rochester, MN, USA
Am J Health Syst Pharm 64:1927-34
..CONCLUSION: Noncompliance with antimicrobial prophylaxis guidelines was associated with low end-of-procedure antibiotic levels. Compliance with guidelines did not guarantee adequate levels...
Elective intestinal operations in infants and children without mechanical bowel preparation: a pilot studyCharles M Leys
Department of Surgery, Vanderbilt Children's Hospital, Vanderbilt University Medical Center, Nashville, TN 37203, USA
J Pediatr Surg 40:978-81; discussion 982
Department of Surgery, Vanderbilt Children's Hospital, Vanderbilt University Medical Center, Nashville, TN 37203, USA
J Pediatr Surg 40:978-81; discussion 982
..These findings warrant a large, prospective, randomized clinical trial to validate our findings and to investigate further the necessity of MBP in the pediatric population...
Successful control program to implement the appropriate antibiotic prophylaxis for Cesarean sectionSilvia Nunes Szente Fonseca
Department of Infection Control, Ribeirão Preto, SP, Brazil
Rev Inst Med Trop Sao Paulo 50:79-82
Department of Infection Control, Ribeirão Preto, SP, Brazil
Rev Inst Med Trop Sao Paulo 50:79-82
....
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