seeds

Summary

Summary: The encapsulated embryos of flowering plants. They are used as is or for animal feed because of the high content of concentrated nutrients like starches, proteins, and fats. Rapeseed, cottonseed, and sunflower seed are also produced for the oils (fats) they yield.

Top Publications

  1. pmc LEAFY COTYLEDON1-LIKE defines a class of regulators essential for embryo development
    Raymond W Kwong
    Section of Plant Biology, Division of Biological Sciences, One Shields Avenue, University of California, Davis, California 95616, USA
    Plant Cell 15:5-18. 2003
  2. ncbi ABA induction of miR159 controls transcript levels of two MYB factors during Arabidopsis seed germination
    Jose L Reyes
    Laboratory of Plant Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Plant J 49:592-606. 2007
  3. pmc Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing
    Qing Xin Song
    State Key Laboratory of Plant Genomics, Genome Biology Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PR China
    BMC Plant Biol 11:5. 2011
  4. pmc Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism
    Michael Riefler
    Institute of Biology Applied Genetics, Free University of Berlin, Germany
    Plant Cell 18:40-54. 2006
  5. pmc Association mapping of kernel size and milling quality in wheat (Triticum aestivum L.) cultivars
    Flavio Breseghello
    Department of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genetics 172:1165-77. 2006
  6. ncbi Arabidopsis LEAFY COTYLEDON1 is sufficient to induce embryo development in vegetative cells
    T Lotan
    Division of Biological Sciences, University of California, Davis 95616, USA
    Cell 93:1195-205. 1998
  7. ncbi A QTL for rice grain width and weight encodes a previously unknown RING-type E3 ubiquitin ligase
    Xian Jun Song
    National Key Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, The Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
    Nat Genet 39:623-30. 2007
  8. ncbi Seed dormancy and the control of germination
    William E Finch-Savage
    Warwick HRI, Warwick University, Wellesbourne, Warwick CV35 9EF, UK
    New Phytol 171:501-23. 2006
  9. ncbi The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access
    Hideki Goda
    RIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Plant J 55:526-42. 2008
  10. pmc Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions
    George W Bassel
    Division of Plant and Crop Sciences, School of Biosciences and Centre for Plant Integrative Biology, University of Nottingham, Loughborough LE12 5RD, United Kingdom
    Proc Natl Acad Sci U S A 108:9709-14. 2011

Detail Information

Publications272 found, 100 shown here

  1. pmc LEAFY COTYLEDON1-LIKE defines a class of regulators essential for embryo development
    Raymond W Kwong
    Section of Plant Biology, Division of Biological Sciences, One Shields Avenue, University of California, Davis, California 95616, USA
    Plant Cell 15:5-18. 2003
    ..Our results also suggest that LEC1-type HAP3 subunits arose from a common origin uniquely in plants. Thus, L1L, an essential regulator of embryo development, defines a unique class of plant HAP3 subunits...
  2. ncbi ABA induction of miR159 controls transcript levels of two MYB factors during Arabidopsis seed germination
    Jose L Reyes
    Laboratory of Plant Molecular Biology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA
    Plant J 49:592-606. 2007
    ..Here, we show that, in germinating Arabidopsis thaliana seeds, ABA induces the accumulation of microRNA 159 (miR159) in an ABI3-dependent fashion, and miRNA159 mediates ..
  3. pmc Identification of miRNAs and their target genes in developing soybean seeds by deep sequencing
    Qing Xin Song
    State Key Laboratory of Plant Genomics, Genome Biology Center, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, PR China
    BMC Plant Biol 11:5. 2011
    ....
  4. pmc Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism
    Michael Riefler
    Institute of Biology Applied Genetics, Free University of Berlin, Germany
    Plant Cell 18:40-54. 2006
    ..Mutant seeds had more rapid germination, reduced requirement for light, and decreased far-red light sensitivity, unraveling ..
  5. pmc Association mapping of kernel size and milling quality in wheat (Triticum aestivum L.) cultivars
    Flavio Breseghello
    Department of Plant Breeding and Genetics, Cornell University, Ithaca, New York 14853, USA
    Genetics 172:1165-77. 2006
    ..Our results demonstrated that association mapping could complement and enhance previous QTL information for marker-assisted selection...
  6. ncbi Arabidopsis LEAFY COTYLEDON1 is sufficient to induce embryo development in vegetative cells
    T Lotan
    Division of Biological Sciences, University of California, Davis 95616, USA
    Cell 93:1195-205. 1998
    ..Our results suggest that LEC1 is an important regulator of embryo development that activates the transcription of genes required for both embryo morphogenesis and cellular differentiation...
  7. ncbi A QTL for rice grain width and weight encodes a previously unknown RING-type E3 ubiquitin ligase
    Xian Jun Song
    National Key Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institute for Biological Sciences, The Chinese Academy of Sciences, 300 Fenglin Road, Shanghai 200032, China
    Nat Genet 39:623-30. 2007
    ..The functional characterization of GW2 provides insight into the mechanism of seed development and is a potential tool for improving grain yield in crops...
  8. ncbi Seed dormancy and the control of germination
    William E Finch-Savage
    Warwick HRI, Warwick University, Wellesbourne, Warwick CV35 9EF, UK
    New Phytol 171:501-23. 2006
    ..We argue that adaptation has taken place on a theme rather than via fundamentally different paths and identify similarities underlying the extensive diversity in the dormancy response to the environment that controls germination...
  9. ncbi The AtGenExpress hormone and chemical treatment data set: experimental design, data evaluation, model data analysis and data access
    Hideki Goda
    RIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Plant J 55:526-42. 2008
    ..The data set presented here will be a versatile resource for future hormone studies, and constitutes a reference for genome-wide gene expression in Arabidopsis...
  10. pmc Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions
    George W Bassel
    Division of Plant and Crop Sciences, School of Biosciences and Centre for Plant Integrative Biology, University of Nottingham, Loughborough LE12 5RD, United Kingdom
    Proc Natl Acad Sci U S A 108:9709-14. 2011
    ..SeedNet is available as a community resource (http://vseed.nottingham.ac.uk) to aid dissection of this complex trait and gene function in diverse processes...
  11. pmc MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesis
    Michael D Nodine
    Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA
    Genes Dev 24:2678-92. 2010
    ..We propose that, by preventing precocious expression of differentiation-promoting transcription factors, miRNAs enable proper embryonic patterning...
  12. pmc MicroRNAs regulate the timing of embryo maturation in Arabidopsis
    Matthew R Willmann
    Department of Biology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Plant Physiol 155:1871-84. 2011
    ..Mature seeds are dormant and desiccated, with accumulated storage products that are to be used by the seedling after ..
  13. doi Genome-wide analysis of endogenous abscisic acid-mediated transcription in dry and imbibed seeds of Arabidopsis using tiling arrays
    Masanori Okamoto
    RIKEN Plant Science Center, Yokohama, Kanagawa 230 0045, Japan
    Plant J 62:39-51. 2010
    ..To understand how endogenous ABA regulates the transcriptomes in seeds, we performed comprehensive expression analyses using whole-genome Affymetrix tiling arrays in two ABA metabolism ..
  14. pmc Cytokinin regulates the activity of reproductive meristems, flower organ size, ovule formation, and thus seed yield in Arabidopsis thaliana
    Isabel Bartrina
    Institute of Biology Applied Genetics, Dahlem Centre of Plant Sciences, Freie Universitat Berlin, D 14195 Berlin, Germany
    Plant Cell 23:69-80. 2011
    ..Together, the results underpin the important role of cytokinin in reproductive development. The increased cytokinin content caused an ~55% increase in seed yield, highlighting the relevance of sink strength as a yield factor...
  15. ncbi GS3, a major QTL for grain length and weight and minor QTL for grain width and thickness in rice, encodes a putative transmembrane protein
    Chuchuan Fan
    National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research Wuhan, Huazhong Agricultural University, 430070 Wuhan, China
    Theor Appl Genet 112:1164-71. 2006
    ..Cloning of such a gene provided the opportunity for fully characterizing the regulatory mechanism and related processes during grain development...
  16. pmc CYP707A1 and CYP707A2, which encode abscisic acid 8'-hydroxylases, are indispensable for proper control of seed dormancy and germination in Arabidopsis
    Masanori Okamoto
    RIKEN Plant Science Center, Yokohama, Kanagawa 230 0045, Japan
    Plant Physiol 141:97-107. 2006
    ..encode ABA 8'-hydroxylases, and that the cyp707a2 mutants showed an increase in ABA levels in dry and imbibed seeds. In this study, we showed that the cyp707a1 mutant accumulated ABA to higher levels in dry seeds than the cyp707a2 ..
  17. ncbi ABI5 acts downstream of ABI3 to execute an ABA-dependent growth arrest during germination
    Luis Lopez-Molina
    Laboratory of Plant Molecular Biology, Laboratory for Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, 1230 York Avenue, New York, NY 10021 6399, USA
    Plant J 32:317-28. 2002
    ..Although ABI5 is consistently located in the nucleus, chromosomal immunoprecipitation (ChIP) experiments revealed that ABA increases ABI5 occupancy on the AtEm6 promoter...
  18. pmc The Arabidopsis cytochrome P450 CYP707A encodes ABA 8'-hydroxylases: key enzymes in ABA catabolism
    Tetsuo Kushiro
    Plant Science Center, RIKEN, Yokohama, Japan
    EMBO J 23:1647-56. 2004
    ..Consistent with the expression analyses, cyp707a2 mutants exhibited hyperdormancy in seeds and accumulated six-fold greater ABA content than wild type...
  19. ncbi Genome-wide profiling of stored mRNA in Arabidopsis thaliana seed germination: epigenetic and genetic regulation of transcription in seed
    Kazumi Nakabayashi
    Plant Science Center, RIKEN, Suehiro cho 1 7 22, Tsurumi, Yokohama, Kanagawa 230 0045, Japan
    Plant J 41:697-709. 2005
    ..Statistical analysis revealed that promoters of highly expressed genes in wild-type dry seeds overrepresented abscisic acid-responsive elements (ABREs) containing the core motif ACGT...
  20. ncbi An SNP caused loss of seed shattering during rice domestication
    Saeko Konishi
    Institute of the Society for Techno Innovation of Agriculture, Forestry, and Fisheries, 446 1 Ippaizuka, Kamiyokoba Tsukuba, Ibaraki 305 0854, Japan
    Science 312:1392-6. 2006
    ....
  21. ncbi Repression of AUXIN RESPONSE FACTOR10 by microRNA160 is critical for seed germination and post-germination stages
    Po Pu Liu
    Department of Horticulture, Oregon State University, Corvallis, OR 97331, USA
    Plant J 52:133-46. 2007
    ..During sensu stricto germination and post-germination, mARF10 mutant seeds and plants were hypersensitive to ABA in a dose-dependent manner...
  22. pmc Gene expression analysis of flax seed development
    Prakash Venglat
    Plant Biotechnology Institute, NRC, 110 Gymnasium Place, Saskatoon, Saskatchewan, S7N 0W9, Canada
    BMC Plant Biol 11:74. 2011
    ..is an important crop whose seed oil and stem fiber have multiple industrial applications. Flax seeds are also well-known for their nutritional attributes, viz...
  23. doi Expression of ER quality control-related genes in response to changes in BiP1 levels in developing rice endosperm
    Yuhya Wakasa
    Transgenic Crop Research and Development Center, National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 65:675-89. 2011
    ..Judicious modification of BiP1 levels in transgenic rice can provide suitable conditions for the production of secretory proteins by alleviating ER stress...
  24. doi Family life at close quarters: communication and constraint in angiosperm seed development
    Gwyneth Christina Ingram
    Institute of Molecular Plant Sciences, University of Edinburgh, Edinburgh, UK
    Protoplasma 247:195-214. 2010
    The formation of viable angiosperm seeds involves the co-ordinated growth and development of three genetically distinct organisms, the maternally derived seed coat and the zygotic embryo and endosperm...
  25. ncbi Molecular aspects of seed dormancy
    Ruth Finkelstein
    Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, California 93106 9610, USA
    Annu Rev Plant Biol 59:387-415. 2008
    ..The net result is a slightly heterogeneous response, thereby providing more temporal options for successful germination...
  26. ncbi A comparative linkage map of oilseed rape and its use for QTL analysis of seed oil and erucic acid content
    D Qiu
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, 1 Shizishan, 430070, Wuhan, China
    Theor Appl Genet 114:67-80. 2006
    ..The results provide new insights into the genetic control of seed oil and erucic acid content in oilseed rape, and demonstrate the utility of the linkage map and population...
  27. ncbi Role of anthocyanidin reductase, encoded by BANYULS in plant flavonoid biosynthesis
    De Yu Xie
    Plant Biology Division, Samuel Roberts Noble Foundation, 2510 Sam Noble Parkway, Ardmore, OK 73401, USA
    Science 299:396-9. 2003
    ..Ectopic expression of BAN in tobacco flower petals and Arabidopsis leaves results in loss of anthocyanins and accumulation of CTs...
  28. ncbi Molecular networks regulating Arabidopsis seed maturation, after-ripening, dormancy and germination
    Michael J Holdsworth
    Department of Agricultural and Environmental Sciences, School of Biosciences, University of Nottingham, Nottingham LE12 5RD, UK
    New Phytol 179:33-54. 2008
    ..Combined postgenomics, physiology and molecular genetics approaches are beginning to provide an unparalleled understanding of the molecular processes underlying dormancy and germination...
  29. pmc Gene coexpression clusters and putative regulatory elements underlying seed storage reserve accumulation in Arabidopsis
    Fred Y Peng
    Agricultural Lipid Biotechnology Program, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
    BMC Genomics 12:286. 2011
    ..A more holistic view of this molecular interplay will help in the further study of the regulatory mechanisms controlling seed storage compound accumulation...
  30. doi From the soil to the seeds: the long journey of nitrate in plants
    Julie Dechorgnat
    Institut Jean Pierre Bourgin, UMR 1318 INRA AgroParisTech, Institut National de la Recherche Agronomique, Route de St Cyr, F 78026 Versailles, France
    J Exp Bot 62:1349-59. 2011
    ..All these fluxes are controlled by key factors, the 'major tour operators' like the internal nutritional status of the plant but also by external abiotic factors...
  31. doi Natural variation in GS5 plays an important role in regulating grain size and yield in rice
    Yibo Li
    National Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research, Huazhong Agricultural University, Wuhan, China
    Nat Genet 43:1266-9. 2011
    ..The results suggest that natural variation in GS5 contributes to grain size diversity in rice and may be useful in improving yield in rice and, potentially, other crops(2)...
  32. pmc Genomic diversity and introgression in O. sativa reveal the impact of domestication and breeding on the rice genome
    Keyan Zhao
    Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA
    PLoS ONE 5:e10780. 2010
    ..However, genetic uniformity surrounding key domestication genes across divergent subpopulations suggests cultural exchange of genetic material among ancient farmers...
  33. ncbi Pharmacological and toxicological properties of Nigella sativa
    B H Ali
    Department of Veterinary Medicine, King Saud University, Buraydah, Al Gaseem 81999, Saudi Arabia
    Phytother Res 17:299-305. 2003
    The seeds of Nigella sativa Linn...
  34. pmc Unraveling the complex trait of crop yield with quantitative trait loci mapping in Brassica napus
    Jiaqin Shi
    National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan, China
    Genetics 182:851-61. 2009
    ..The idea of estimating indicator QTL for yield QTL and identifying potential candidate genes for yield provides an advance in methodology for complex traits...
  35. doi Differential expression of the microRNAs in superior and inferior spikelets in rice (Oryza sativa)
    Ting Peng
    Research Center for Rice Engineering and Key Laboratory of Physiology, Ecology and Genetic Improvement of Food Crops in Henan Province, Henan Agricultural University, Zhengzhou, 450002, China
    J Exp Bot 62:4943-54. 2011
    ..The results indicate that the slow grain-filling and low grain weight of rice inferior spikelets are attributed partly to differences in expression and function between superior and inferior spikelet miRNAs...
  36. pmc Extensive demethylation of repetitive elements during seed development underlies gene imprinting
    Mary Gehring
    Howard Hughes Medical Institute HHMI, Fred Hutchinson Cancer Research Center FHCRC, 1100 Fairview Avenue North, Seattle, WA 98109, USA
    Science 324:1447-51. 2009
    ..These data suggest that imprinting in plants evolved from targeted methylation of transposable element insertions near genic regulatory elements followed by positive selection when the resulting expression change was advantageous...
  37. ncbi High-throughput peptide mass fingerprinting of soybean seed proteins: automated workflow and utility of UniGene expressed sequence tag databases for protein identification
    Brian P Mooney
    Department of Biochemistry and Proteomics Center, University of Missouri Columbia, 125 Chemistry, Columbia, MO 65211, USA
    Phytochemistry 65:1733-44. 2004
    ..This survey of anonymous seed proteins will serve as the basis for future comparative analysis of seed-filling in soybean as well as comparisons with other soybean varieties...
  38. pmc Mutations in UDP-Glucose:sterol glucosyltransferase in Arabidopsis cause transparent testa phenotype and suberization defect in seeds
    Seth DeBolt
    Department of Horticulture, University of Kentucky, Lexington, Kentucky 40506, USA
    Plant Physiol 151:78-87. 2009
    ..An ancillary observation was that cellulose biosynthesis was unaffected in the double mutant, inconsistent with a predicted role for SGs in priming cellulose synthesis...
  39. ncbi A conditionally fertile coi1 allele indicates cross-talk between plant hormone signalling pathways in Arabidopsis thaliana seeds and young seedlings
    Christine Ellis
    School of Biological Sciences, University of East Anglia, Norwich, NR4 7TJ, UK
    Planta 215:549-56. 2002
    ..We have used coi1-16 seeds to define novel interactions between JA and other hormone signalling pathways in seed germination and in the ..
  40. ncbi Early infection of scutellum tissue with Agrobacterium allows high-speed transformation of rice
    Seiichi Toki
    Plant Genetic Engineering Research Unit, National Institute of Agrobiological Sciences, 2 1 2 Kannondai, Tsukuba, Ibaraki 305 8602, Japan
    Plant J 47:969-76. 2006
    ..Here, we report the competency of scutellum tissue from 1-day pre-cultured seeds for Agrobacterium-mediated transformation...
  41. ncbi Seed dormancy and germination
    Maarten Koornneef
    Laboratory of Genetics, Department of Plant Sciences, Wageningen University, Arboretumlaan 4, 6703 BD, Wageningen, The Netherlands
    Curr Opin Plant Biol 5:33-6. 2002
    ..These tools preferentially use Arabidopsis thaliana because of the molecular genetic resources available for this species. However, Solanaceae and cereals also provide important models for dormancy research...
  42. ncbi Expression profiling of genes involved in starch synthesis in sink and source organs of rice
    Takashi Ohdan
    Core Research for Evolutional Science and Technology CREST, Japan Science and Technology Agency JST, 4 1 8, Honcho, Kawaguchi, Saitama 332 0012, Japan
    J Exp Bot 56:3229-44. 2005
    ..branching enzyme, starch debranching enzyme, starch phosphorylase, and disproportionating enzyme in developing seeds and leaves. The modes of gene expression were tissue- and developmental stage-specific...
  43. ncbi Apyap1 affects aflatoxin biosynthesis during Aspergillus parasiticus growth in maize seeds
    M Reverberi
    Universita degli Studi La Sapienza, 00165 Rome, Italy
    Food Addit Contam 24:1070-5. 2007
    ..This study suggests that an association between oxidative stress and aflatoxin biosynthesis also occurs in maize seeds. We used DeltaApyap1, a strain in which the gene Apyap1 was disrupted, to verify whether this oxidative stress-..
  44. pmc A novel transcriptional cascade regulating expression of heat stress proteins during seed development of Arabidopsis
    Sachin Kotak
    Institute of Molecular Biosciences, Biocenter N200 R306, Goethe University, D 60439 Frankfurt, Germany
    Plant Cell 19:182-95. 2007
    ..Consequently, the most abundant heat stress proteins (Hsps) in seeds (Hsp17.4-CI, Hsp17...
  45. pmc Genetic analysis of functions involved in adhesion of Pseudomonas putida to seeds
    M Espinosa-Urgel
    Department of Plant Biochemistry, Estacion Experimental del Zaidin, Consejo Superior de Investigaciones Cientificas, E 18008 Granada, Spain
    J Bacteriol 182:2363-9. 2000
    ..require the establishment of efficient bacterial populations in the rhizosphere, for which colonization of plant seeds often constitutes a critical first step...
  46. pmc Biochemical and genetic analysis of the effects of amylose-extender mutation in rice endosperm
    A Nishi
    Faculty of Agriculture, Kyushu University, Hakozaki, Higashi ku, Fukuoka 812 8581, Japan
    Plant Physiol 127:459-72. 2001
    ..These results strongly suggest that BEIIb plays a specific role in the transfer of short chains, which might then be extended by SS to form the A and B(1) chains of amylopectin cluster in rice endosperm...
  47. ncbi Subcellular targeting is a key condition for high-level accumulation of cellulase protein in transgenic maize seed
    Elizabeth E Hood
    Arkansas State University, PO Box 2760, State University, AR 72467, USA
    Plant Biotechnol J 5:709-19. 2007
    ..Recovery of high levels of enzyme in T2 ears demonstrated that expression is likely to be stable over multiple generations. The enzymes were active in cleaving soluble substrate...
  48. pmc The gibberellic acid signaling repressor RGL2 inhibits Arabidopsis seed germination by stimulating abscisic acid synthesis and ABI5 activity
    Urszula Piskurewicz
    Universite de Geneve, Département de Biologie Végétale, 1211 Geneva 4, Switzerland
    Plant Cell 20:2729-45. 2008
    ..In sleepy1 mutant seeds, RGL2 overaccumulates; germination of these seeds can occur under conditions that produce low ABI5 expression...
  49. doi Arabidopsis seed secrets unravelled after a decade of genetic and omics-driven research
    Helen North
    INRA, Seed Biology Laboratory, Institut Jean Pierre Bourgin IJPB, UMR 204 INRA AgroParisTech, Versailles Cedex, France
    Plant J 61:971-81. 2010
    b>Seeds play a fundamental role in colonization of the environment by spermatophytes, and seeds harvested from crops are the main food source for human beings...
  50. pmc Strigolactones stimulate arbuscular mycorrhizal fungi by activating mitochondria
    Arnaud Besserer
    UMR 5546, Pôle de Biotechnologies Végétales, Castanet Tolosan, France
    PLoS Biol 4:e226. 2006
    ..intraradices. We conclude that strigolactones are important rhizospheric plant signals involved in stimulating both the pre-symbiotic growth of AM fungi and the germination of parasitic plants...
  51. ncbi Comparative organization of chloroplast, mitochondrial and nuclear diversity in plant populations
    Remy J Petit
    INRA, UMR Biodiversity, Genes and Ecosystems, 69 route d Arcachon, F 33612 Cestas cedex, France
    Mol Ecol 14:689-701. 2005
    ....
  52. pmc Abscisic acid signaling in seeds and seedlings
    Ruth R Finkelstein
    Department of Molecular, Cellular, and Developmental Biology, University of California at Santa Barbara, Santa Barbara, CA 93106, USA
    Plant Cell 14:S15-45. 2002
  53. pmc Class III homeodomain-leucine zipper gene family members have overlapping, antagonistic, and distinct roles in Arabidopsis development
    Michael J Prigge
    Department of Molecular, Cellular and Developmental Biology, University of Michigan, An Arbor, Michigan 48109 1048, USA
    Plant Cell 17:61-76. 2005
    ..Differences in expression patterns explain some of these genetic interactions, whereas other interactions are likely attributable to differences in protein function as indicated by cross-complementation studies...
  54. pmc Endogenous, tissue-specific short interfering RNAs silence the chalcone synthase gene family in glycine max seed coats
    Jigyasa H Tuteja
    Department of Crop Sciences, University of Illinois, Urbana, Illinois 61801, USA
    Plant Cell 21:3063-77. 2009
    ....
  55. ncbi DEMETER, a DNA glycosylase domain protein, is required for endosperm gene imprinting and seed viability in arabidopsis
    Yeonhee Choi
    Department of Plant and Microbial Biology, University of California, Berkeley, Berkeley, CA 94720, USA
    Cell 110:33-42. 2002
    ..In leaf, ectopic DME expression induces MEA and nicks the MEA promoter. Thus, a DNA glycosylase activates maternal expression of an imprinted gene in the central cell...
  56. pmc Genome-wide demethylation of Arabidopsis endosperm
    Tzung Fu Hsieh
    Department of Plant and Microbial Biology, University of California, Berkeley, CA 94720, USA
    Science 324:1451-4. 2009
    ..Our findings demonstrate extensive reconfiguration of the endosperm methylation landscape that likely reinforces transposon silencing in the embryo...
  57. ncbi Transcriptional regulation of ABI3- and ABA-responsive genes including RD29B and RD29A in seeds, germinating embryos, and seedlings of Arabidopsis
    Kazuo Nakashima
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, JIRCAS, 1 1 Ohwashi, Tsukuba, 305 8686, Japan
    Plant Mol Biol 60:51-68. 2006
    ..analysis using abi3 and abi5 mutants showed that ABI3 and ABI5 play important roles in the expression of RD29B in seeds. Base-substitution analysis showed that two ABREs function strongly and one ABRE coupled with DRE functions weakly ..
  58. pmc Variation in expression and protein localization of the PIN family of auxin efflux facilitator proteins in flavonoid mutants with altered auxin transport in Arabidopsis thaliana
    Wendy Ann Peer
    Department of Horticulture, Purdue University, West Lafayette, Indiana 47907 2010, USA
    Plant Cell 16:1898-911. 2004
    ..In some auxin-accumulating tissues, flavonoid increases and changes in flavonoid speciation are subsequent to auxin accumulation...
  59. pmc Mobilization of vacuolar iron by AtNRAMP3 and AtNRAMP4 is essential for seed germination on low iron
    Viviane Lanquar
    Institut des Sciences du Vegetal, CNRS, Gif sur Yvette, France
    EMBO J 24:4041-51. 2005
    ..Mutant seeds have wild type Fe content, but fail to retrieve Fe from the vacuolar globoids...
  60. pmc Development of maternal seed tissue in barley is mediated by regulated cell expansion and cell disintegration and coordinated with endosperm growth
    Volodymyr Radchuk
    Leibniz Institut für Pflanzengenetik und Kulturpflanzenforschung, Corrensstraße 3, D 06466 Gatersleben, Germany
    J Exp Bot 62:1217-27. 2011
    ..Possible functions of PCD in the maternal tissues imply a potential nutritive role or the relief of a physical restraint for endosperm growth. PCD could also activate post-phloem transport functions...
  61. pmc Large-scale production of functional human serum albumin from transgenic rice seeds
    Yang He
    Engineering Research Center for Plant Biotechnology and Germplasm Utilization, Ministry of Education, State Key Laboratory of Hybrid Rice, College of Life Sciences, Wuhan University, Wuhan 430072, China
    Proc Natl Acad Sci U S A 108:19078-83. 2011
    ..Here, we report the production of Oryza sativa recombinant HSA (OsrHSA) from transgenic rice seeds. The level of OsrHSA reached 10.58% of the total soluble protein of the rice grain...
  62. pmc LEAFY COTYLEDON2 encodes a B3 domain transcription factor that induces embryo development
    S L Stone
    Section of Plant Biology, Division of Biological Sciences, University of California, One Shields Avenue, Davis, CA 95616, USA
    Proc Natl Acad Sci U S A 98:11806-11. 2001
    ..that LEC2 shares greatest similarity with the B3 domain transcription factors that act primarily in developing seeds, VIVIPAROUS1/ABA INSENSITIVE3 and FUSCA3...
  63. pmc Regulation of expression of starch synthesis genes by ethylene and ABA in relation to the development of rice inferior and superior spikelets
    Guohui Zhu
    College of Life Sciences, South China Agricultural University, Guangdong, China
    J Exp Bot 62:3907-16. 2011
    ....
  64. pmc High temperature-induced abscisic acid biosynthesis and its role in the inhibition of gibberellin action in Arabidopsis seeds
    Shigeo Toh
    Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki, Kanagawa, Japan
    Plant Physiol 146:1368-85. 2008
    ..Here, we show that ABA levels in imbibed seeds are elevated at high temperature and that this increase is correlated with up-regulation of the zeaxanthin ..
  65. ncbi A phenylalanine in DGAT is a key determinant of oil content and composition in maize
    Peizhong Zheng
    Pioneer Hi Bred International Inc, A DuPont Company, 7300 NW 62nd Avenue, PO Box 1004, Johnston, Iowa 50131, USA
    Nat Genet 40:367-72. 2008
    ..This work provides insights into the molecular basis of natural variation of oil and oleic-acid contents in plants and highlights DGAT as a promising target for increasing oil and oleic-acid contents in other crops...
  66. ncbi Iron accumulation does not parallel the high expression level of ferritin in transgenic rice seeds
    Le Qing Qu
    Laboratory of Genetic Engineering, Department of Plant Biotechnology, National Institute of Agrobiological Sciences, Kannondai 2 1 2, Tsukuba, Ibaraki 305 8602, Japan
    Planta 222:225-33. 2005
    To answer the question whether iron accumulation in transgenic rice seeds depends on the expression level of exogenous soybean ferritin, we generated two kinds of ferritin hyper-expressing rice lines by introducing soybean ferritin ..
  67. doi Transcription factors regulating the progression of monocot and dicot seed development
    Pinky Agarwal
    Interdisciplinary Centre for Plant Genomics, Department of Plant Molecular Biology, University of Delhi South Campus, New Delhi, India
    Bioessays 33:189-202. 2011
    ..An understanding of this interplay will not only help unravel an integrated developmental process, but will also pave the way for biotechnological applications...
  68. ncbi The MADS box genes SEEDSTICK and ARABIDOPSIS Bsister play a maternal role in fertilization and seed development
    Chiara Mizzotti
    Dipartimento di Biologia, Universita degli Studi di Milano, Via Celoria 26, 20133 Milan, Italy
    Plant J 70:409-20. 2012
    ..Here we describe the characterization of the abs stk double mutant. This double mutant develops very few seeds due to both a reduced number of fertilized ovules and seed abortions later during development...
  69. pmc Evolutionary history of GS3, a gene conferring grain length in rice
    Noriko Takano-Kai
    Faculty of Agriculture, Kyushu University, Fukuoka 812 8581, Japan
    Genetics 182:1323-34. 2009
    ..This study indicates a critical role for GS3 in defining the seed morphologies of modern subpopulations of O. sativa and enhances the potential for genetic manipulation of grain size in rice...
  70. ncbi Translocation of neonicotinoid insecticides from coated seeds to seedling guttation drops: a novel way of intoxication for bees
    V Girolami
    Dipartimento di Agronomia Ambientale e Produzioni Vegetali, Entomologia, Universita di Padova, Viale dell Universita 16, 35020 Legnaro, Padova, Italy
    J Econ Entomol 102:1808-15. 2009
    ..Here, we show that leaf guttation drops of all the corn plants germinated from neonicotinoid-coated seeds contained amounts of insecticide constantly higher than 10 mg/l, with maxima up to 100 mg/l for thiamethoxam and ..
  71. ncbi Temporal expression patterns of hormone metabolism genes during imbibition of Arabidopsis thaliana seeds: a comparative study on dormant and non-dormant accessions
    Jeremy Preston
    Growth Regulation Research Group, RIKEN Plant Science Center, 1 7 22, Suehiro cho, Tsurumi, Yokohama, 230 0045, Japan
    Plant Cell Physiol 50:1786-800. 2009
    ..Here, we investigated imbibition responses of Arabidopsis seeds by transcriptomic and hormone profile analyses using dormant [Cape Verde Islands (Cvi)] and non-dormant [Columbia (..
  72. pmc Regulatory networks in seeds integrating developmental, abscisic acid, sugar, and light signaling
    Inès M Brocard-Gifford
    Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, California 93106, USA
    Plant Physiol 131:78-92. 2003
    ....
  73. ncbi Dietary feeding of proanthocyanidins from grape seeds prevents photocarcinogenesis in SKH-1 hairless mice: relationship to decreased fat and lipid peroxidation
    Anshu Mittal
    Department of Dermatology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
    Carcinogenesis 24:1379-88. 2003
    ..Dietary feeding of proanthocyanidins extracted from grape seeds (GSP) (0.2 and 0...
  74. doi Paternal control of embryonic patterning in Arabidopsis thaliana
    Martin Bayer
    Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
    Science 323:1485-8. 2009
    ..We propose that SSP protein produced from paternal transcripts upon fertilization triggers zygotic YDA activity, providing an essential temporal cue for the regulation of the asymmetric first division...
  75. ncbi Epigenetic resetting of a gene imprinted in plant embryos
    Stephanie Jahnke
    Developmental Biology and Biotechnology, Biocenter Klein Flottbek, University of Hamburg, Ohnhorststrasse 18, 22609 Hamburg, Germany
    Curr Biol 19:1677-81. 2009
    ..The striking difference between the regulation of imprinting in the embryo and endosperm suggests that imprinting mechanisms might have evolved independently in both fertilization products of flowering plants...
  76. pmc MATERNALLY EXPRESSED PAB C-TERMINAL, a novel imprinted gene in Arabidopsis, encodes the conserved C-terminal domain of polyadenylate binding proteins
    Sushma Tiwari
    Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, United Kingdom
    Plant Cell 20:2387-98. 2008
    ..In Arabidopsis, DEMETER (DME) activates expression of maternal alleles. MPC expression is reduced in flowers and seeds in a dme-4 mutant but only after fertilization in dme-1...
  77. ncbi Arabidopsis NF-YB subunits LEC1 and LEC1-LIKE activate transcription by interacting with seed-specific ABRE-binding factors
    Akiko Yamamoto
    Bioscience and Biotechnology Center, Nagoya University, Chikusa ku, Nagoya, Japan
    Plant J 58:843-56. 2009
    ..These results demonstrate a novel plant-specific mechanism for NF-Y subunit function that enables LEC1 and L1L to regulate a defined developmental network...
  78. ncbi Stored and neosynthesized mRNA in Arabidopsis seeds: effects of cycloheximide and controlled deterioration treatment on the resumption of transcription during imbibition
    Mitsuhiro Kimura
    Department of Cell and Systems Biology, University of Toronto, 25 Willcocks Street, Toronto, ON M5S3B2, Canada
    Plant Mol Biol 73:119-29. 2010
    Dry seeds accumulate translatable mRNAs as well as functional proteins for transcription and translation. They are possibly involved in early physiological responses after imbibition, however, their functions remain poorly understood...
  79. pmc The Arabidopsis histone deacetylases HDA6 and HDA19 contribute to the repression of embryonic properties after germination
    Motoki Tanaka
    Graduate School of Life and Environmental Sciences, University of Tsukuba, Ibaraki, Japan
    Plant Physiol 146:149-61. 2008
    ..These results suggest that during germination in Arabidopsis, HDA6 and HDA19 redundantly regulate the repression of embryonic properties directly or indirectly via repression of embryo-specific gene function...
  80. doi Comparative proteome analysis of metabolic proteins from seeds of durum wheat (cv. Svevo) subjected to heat stress
    Paolo Laino
    Department of Agrobiology and Agrochemistry, University of Tuscia, Viterbo, Italy
    Proteomics 10:2359-68. 2010
    ..Many of the heat-induced polypeptides are considered to be allergenic for sensitive individuals...
  81. ncbi Tailoring plant lipid composition: designer oilseeds come of age
    Johnathan A Napier
    Department of Biological Chemistry, Rothamsted Research, Harpenden, Herts AL5 2JQ, UK
    Curr Opin Plant Biol 13:330-7. 2010
    ..The new approaches and outcomes described here will inform new paradigms and hasten the arrival of truly predictive biology in this vital field...
  82. pmc The Arabidopsis SeedGenes Project
    Iris Tzafrir
    Department of Botany, Oklahoma State University, Stillwater, OK 74078, USA Virginia Bioinformatics Institute, Blacksburg, VA 24061, USA
    Nucleic Acids Res 31:90-3. 2003
    ..This information is needed to focus attention on genes with important cellular functions in a model plant and to assess from a genetic perspective the extent of functional redundancy in the Arabidopsis genome...
  83. pmc Molecular evolution of shattering loci in U.S. weedy rice
    Carrie S Thurber
    Biology Department, University of Massachusetts, Amherst, MA 01003, USA
    Mol Ecol 19:3271-84. 2010
    ..weedy rice accessions, as well as wild and cultivated relatives. We find that all U.S. weedy rice groups shatter seeds easily, despite multiple origins, and in contrast to a decrease in shattering ability seen in cultivated groups...
  84. doi Functional characterization of a UDP-glucose:flavonoid 3-O-glucosyltransferase from the seed coat of black soybean (Glycine max (L.) Merr.)
    Nik Kovinich
    Bioproducts and Bioprocesses, Research Branch, Agriculture and Agri Food Canada, Ottawa, ON, Canada K1A 0C6
    Phytochemistry 71:1253-63. 2010
    ..RT-PCR confirmed the co-expression of one of these genes (Glyma08g07130) with UGT78K1 in the seed coat of black soybean, suggesting possible functional redundancies in anthocyanin biosynthesis in this tissue...
  85. ncbi Seed arrival, ecological filters, and plant species richness: a meta-analysis
    Jonathan A Myers
    Department of Biological Sciences, Division of Systematics, Louisiana State University, Baton Rouge, LA 70803, USA
    Ecol Lett 12:1250-60. 2009
    ..experiments, effect size was positively correlated with species and functional diversity within the pool of added seeds (species evenness and seed-size diversity), primarily in disturbed communities...
  86. doi Glucose-induced delay of seed germination in rice is mediated by the suppression of ABA catabolism rather than an enhancement of ABA biosynthesis
    Guohui Zhu
    College of Life Science, South China Agricultural University, Guangdong, PR China
    Plant Cell Physiol 50:644-51. 2009
    ..increased during the first 6 h of imbibition, which was consistent with the decline of ABA content in the imbibed seeds. Expression of OsABA8ox genes, especially OsABA8ox2 and OsABA8ox3, was sensitively suppressed in the presence of ..
  87. doi Maternal epigenetic pathways control parental contributions to Arabidopsis early embryogenesis
    Daphné Autran
    diversité, Adaptation et Développement des Plantes, Institut de Recherche pour le Developpement, Universite de Montpellier, UMR 232, Montpellier 34394, France
    Cell 145:707-19. 2011
    ..Our results define maternal epigenetic pathways controlling the parental contributions in plant embryos, which are distinct from those regulating genomic imprinting...
  88. ncbi Plant seeds as bioreactors for recombinant protein production
    On Sun Lau
    Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520 8104, USA
    Biotechnol Adv 27:1015-22. 2009
    ..Significant advances in using seeds as bioreactors have occurred in the past decade, which include the first commercialized plant-derived recombinant ..
  89. pmc Anatomical and transcriptomic studies of the coleorhiza reveal the importance of this tissue in regulating dormancy in barley
    José M Barrero
    Plant Industry, Commonwealth Scientific and Industrial Research Organisation, Canberra, Australian Capital Territory 2601, Australia
    Plant Physiol 150:1006-21. 2009
    ....
  90. pmc Plants and people from the Early Neolithic to Shang periods in North China
    Gyoung Ah Lee
    Archaeology Program, La Trobe University, Victoria 3086, Australia
    Proc Natl Acad Sci U S A 104:1087-92. 2007
    ..The North China farming tradition that emphasized dry crops (millets, wheat, and legumes) with some rice appears to have been established at the latest by the Early Shang (Erligang; 1600-1300 B.C.) period...
  91. pmc The protein storage vacuole: a unique compound organelle
    L Jiang
    Department of Biology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    J Cell Biol 155:991-1002. 2001
    ....
  92. ncbi Mechanisms of long-distance dispersal of seeds by wind
    Ran Nathan
    Department of Life Sciences, Ben Gurion University of the Negev, Beer Sheva 84105, Israel
    Nature 418:409-13. 2002
    ..release and aerodynamics with turbulent transport processes provide accurate probabilistic descriptions of LDD of seeds by wind...
  93. pmc Differential contribution of frugivores to complex seed dispersal patterns
    P Jordano
    Integrative Ecology Group and Laboratorio de Ecología Molecular, Estacion Biologica de Donana, Consejo Superior de Investigaciones Cientificas, Pabellón del Perú, Avenida María Luisa, S N, E 41013 Seville, Spain
    Proc Natl Acad Sci U S A 104:3278-82. 2007
    ..We used DNA-based genotyping techniques on Prunus mahaleb seeds dispersed by birds (small- and medium-sized passerines) and carnivorous mammals to infer each seed's source tree, ..
  94. ncbi Role of cell walls in the bioaccessibility of lipids in almond seeds
    Peter R Ellis
    Biopolymers Group, Department of Life Sciences, King s College London, University of London, 150 Stamford Street, London SE1 9NN, UK
    Am J Clin Nutr 80:604-13. 2004
    ..A crucial and relevant aspect is the amount of these dietary components available for absorption in the intestine, which is a concept referred to as bioaccessibility...
  95. pmc Tung tree DGAT1 and DGAT2 have nonredundant functions in triacylglycerol biosynthesis and are localized to different subdomains of the endoplasmic reticulum
    Jay M Shockey
    U S Department of Agriculture, Agricultural Research Service, Southern Regional Research Center, New Orleans, Louisiana 70124, USA
    Plant Cell 18:2294-313. 2006
    b>Seeds of the tung tree (Vernicia fordii) produce large quantities of triacylglycerols (TAGs) containing approximately 80% eleostearic acid, an unusual conjugated fatty acid...
  96. ncbi Antitumor effects of curcin from seeds of Jatropha curcas
    Juan Lin
    College of Life Science, Sichuan University, Chengdu 610064, China
    Acta Pharmacol Sin 24:241-6. 2003
    ..To study the antitumor effects of curcin from Jatropha curcas...
  97. pmc Arabidopsis AtMYC2 (bHLH) and AtMYB2 (MYB) function as transcriptional activators in abscisic acid signaling
    Hiroshi Abe
    Biological Resources Division, Japan International Research Center for Agricultural Sciences, 1 1 Ohwashi, Tsukuba, Ibaraki 305 8686, Japan
    Plant Cell 15:63-78. 2003
    ..These results indicate that both AtMYC2 and AtMYB2 proteins function as transcriptional activators in ABA-inducible gene expression under drought stress in plants...
  98. ncbi Starch synthesis in the cereal endosperm
    Martha G James
    Department of Biochemistry, Biophysics, and Molecular Biology, 1210 Molecular Biology Building, Iowa State University, Ames, Iowa 50011, USA
    Curr Opin Plant Biol 6:215-22. 2003
    ..For the first time, tools for global analyses of starch biosynthesis are available for cereal crops, and are heralded by the draft sequence of the rice genome...
  99. ncbi Molecular characterization of the Arabidopsis 9-cis epoxycarotenoid dioxygenase gene family
    Bao Cai Tan
    Plant Molecular and Cellular Biology Program, University of Florida, Gainesville, FL 32611, USA
    Plant J 35:44-56. 2003
    ..AtNCED5, AtNCED6, AtNCED9, and AtNCED3 contribute to expression in developing seeds with high levels of AtNCED6 present at an early stage...
  100. pmc AtBXL1 encodes a bifunctional beta-D-xylosidase/alpha-L-arabinofuranosidase required for pectic arabinan modification in Arabidopsis mucilage secretory cells
    Andrej A Arsovski
    Biology Department, McGill University, Montreal, Quebec, Canada H3A 1B1
    Plant Physiol 150:1219-34. 2009
    ..Wetting of mature seeds leads to the rapid bursting of these mucilage secretory cells to release a hydrophilic gel that surrounds the seed ..
  101. doi Conserved and novel miRNAs in the legume Phaseolus vulgaris in response to stress
    Catalina Arenas-Huertero
    Departamento de Biologia Molecular de Plantas, Instituto de Biotecnologia, Universidad Nacional Autonoma de Mexico, Av Universidad 2001, Cuernavaca, Morelos, Mexico
    Plant Mol Biol 70:385-401. 2009
    ..vulgaris. We propose that the novel miRNAs present in common bean and other legumes, are involved in regulation of legume-specific processes including adaptation to diverse external cues...

Research Grants75

  1. Salmonella Vaccines Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2010
    ..We will annually amend our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, and submit information to facilitate ..
  2. Mosquito Vector Control Using Bt Coupled to Seed Oil Bodies
    Mohd Amir Abdullah; Fiscal Year: 2009
    ..This Phase I application will test this hypothesis by coupling Bti and BtB to oleosins in the oil-rich seeds of Arabidopsis thaliana...
  3. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2006
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  4. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2004
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  5. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2003
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  6. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2005
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  7. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2004
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  8. S. typhimiurium Vaccine Against Bacterial Enteropathogens
    Roy Curtiss; Fiscal Year: 2007
    ..will also collaboratively work to develop our Master File, prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  9. Stilbene's Contribution in Hemorrhagic Stroke
    SYLVAIN DORE; Fiscal Year: 2010
    The stilbene compound resveratrol is naturally present in grape skin and seeds and is found in particularly high concentrations in red wine...
  10. NMR OF BLOOD COAGULATION PROTEIN INHIBITORS
    Ramaswamy Krishnamoorthi; Fiscal Year: 1993
    ..Trypsin-inhibitors isolated from pumpkin (Cucurbita maxima) seeds, viz...
  11. PROTEIN-CARBOHYDRATE INTERACTION
    Irwin Goldstein; Fiscal Year: 1990
    ..and N-acetyllactosamine with the N-acetyl-D-glucosamine binding lectin from Datura stramonium seeds will be studied...
  12. A New Point of Use Decontamination Method for Fresh Produce
    ADRIAN J DENVIR; Fiscal Year: 2010
    ..Produce related outbreaks of foodborne illness have been attributed to sprouted seeds, leafy vegetables, tomatoes, melons, berries, and unpasteurized juices...
  13. Developing Implantable Miniature Temperature Sensors for Cryosurgery Control
    Yoed Rabin; Fiscal Year: 2010
    ..receiver; and, (iv) sensor localization can be done under imaging guidance, for example, similarly to radiation seeds localization during brachytherapy (local radiation treatment of the prostate)...
  14. High affinity capturing agents for strychnine
    Kit S Lam; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Strychnine is a poisonous indole alkaloid isolated from the seeds of the Indian tree Strychnos nux vomica...
  15. Walnuts vs. Walnut-Oil, Glucose Homeostasis, PCOS
    Sidika Kasim Karakas; Fiscal Year: 2007
    ..improves insulin sensitivity, these women are advised to increase polyunsaturated fat (PUFA) intake from nuts, seeds and fish-oil. This advice is not evidence based...
  16. Walnuts vs. Walnut-Oil, Glucose Homeostasis, PCOS
    Sidika Kasim Karakas; Fiscal Year: 2006
    ..improves insulin sensitivity, these women are advised to increase polyunsaturated fat (PUFA) intake from nuts, seeds and fish-oil. This advice is not evidence based...
  17. INTRACAVITARY HYPERTHERM & RADIATN OF ESOPHAGEAL CANCER
    C Chou; Fiscal Year: 1993
    ..esophageal multilumen polyurethane tube, which can accommodate six channels of temperature sensors or radiation seeds at the periphery, and a microwave antenna in the center of the tube...
  18. INTRACAVITRY HYPERTHERMIA & RADIATN OF ESOPHAGEAL CANCER
    C Chou; Fiscal Year: 1991
    ..esophageal multilumen polyurethane tube, which can accommodate six channels of temperature sensors or radiation seeds at the periphery, and a microwave antenna in the center of the tube...
  19. PLANT TOXINS AND DEMENTIA IN THE WESTERN PACIFIC
    TOM MABRY; Fiscal Year: 1992
    ..a motorneurone disease of India and Africa, is caused by beta-oxalylaminoalanine (L-BOAA) which is present in the seeds of the legume Lathyrus sativus. The seeds of this plant are ground to a flour and used as food...
  20. FERRITIN AND IRON DEFICIENCY--A NEW LOOK AT THE PROBLEM
    Elizabeth Theil; Fiscal Year: 1999
    A sustainable solution to dietary iron deficiency can be achieved in part by increasing bioavailable iron in seeds used for food such as soybeans. Dietary iron deficiency and anemia afflict 1.5 billion people world-wide, approximately 6...
  21. FERRITIN AND IRON DEFICIENCY--A NEW LOOK AT THE PROBLEM
    Elizabeth Theil; Fiscal Year: 2000
    A sustainable solution to dietary iron deficiency can be achieved in part by increasing bioavailable iron in seeds used for food such as soybeans. Dietary iron deficiency and anemia afflict 1.5 billion people world-wide, approximately 6...
  22. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2001
    ..The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field ..
  23. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2004
    ..The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field ..
  24. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2002
    ..The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field ..
  25. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2002
    ..The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field ..
  26. Crossing Borders: HIV and Substance use at the Gateway to North America
    Kimberly C Brouwer; Fiscal Year: 2010
    ..substance using FSWs;Round 2 will focus on the MSM population;and Round 3 will begin with peer recruiters ("seeds") drawn from "mobile" persons- including truck drivers, deportees and regional and international migrants...
  27. Echinacea: Standardized Product & Supply Provision
    Xiping Wang; Fiscal Year: 2003
    ..The source of crude material for subsequent analytical chemistry testing will be first addressed: Echinacea seeds will be tested and identified for purity, then germinated and cultivated at different seasons/soil/field ..
  28. Ferritin and Iron Nutrition in Health and Disease
    Elizabeth Theil; Fiscal Year: 2004
    ..Ferritin is a major source of iron in the early development of humans, other animals and plants. Legume seeds consumed by humans are rich in iron and ferritin...
  29. Ferritin and Iron Nutrition in Health and Disease
    Elizabeth Theil; Fiscal Year: 2005
    ..Ferritin is a major source of iron in the early development of humans, other animals and plants. Legume seeds consumed by humans are rich in iron and ferritin...
  30. Ferritin and Iron Nutrition in Health and Disease
    Elizabeth Theil; Fiscal Year: 2002
    ..Ferritin is a major source of iron in the early development of humans, other animals and plants. Legume seeds consumed by humans are rich in iron and ferritin...
  31. Ferritin and Iron Nutrition in Health and Disease
    Elizabeth Theil; Fiscal Year: 2003
    ..Ferritin is a major source of iron in the early development of humans, other animals and plants. Legume seeds consumed by humans are rich in iron and ferritin...
  32. CANCER EPIDEMIOLOGY IN ADVENTISTS--A LOW RISK GROUP
    Gary Fraser; Fiscal Year: 2007
    ..Nearly half of the population are vegetarian, and many eat dairy products, nuts, seeds and soy, these providing a wide range of dietary linolenic and other long-chain unsaturated acids...
  33. CONTROLLED RELEASE MICROSPHERES FOR RADIATION THERAPY
    Kam Leong; Fiscal Year: 2000
    ..controlled release technology to optimize the efficacy of radiotherapy by local and sustained delivery of radio-seeds arid radiosensitizers...
  34. REGULATION OF AMINO ACID BIOSYNTHESIS GENES IN PLANTS
    Gloria Coruzzi; Fiscal Year: 1999
    ..Nitrogen assimilation into these amino acids affects plant growth and ultimately seeds quantity and quality...
  35. CONTROLLED RELEASE MICROSPHERES FOR RADIATION THERAPY
    Kam Leong; Fiscal Year: 2001
    ..controlled release technology to optimize the efficacy of radiotherapy by local and sustained delivery of radio-seeds arid radiosensitizers...
  36. CONTROLLED RELEASE MICROSPHERES FOR RADIATION THERAPY
    Kam Leong; Fiscal Year: 2002
    ..controlled release technology to optimize the efficacy of radiotherapy by local and sustained delivery of radio-seeds arid radiosensitizers...
  37. A Novel Therapy for Staphylococcal Enterotoxin B Poisoning
    Kenneth J Piller; Fiscal Year: 2010
    ..Oral immunizations using soy milk formulations made from transgenic seeds expressing mutant SEB could elicit protective immunity in mice challenged with lethal doses of native toxin...
  38. Etiology of Balkan endemic nephropathy
    ARTHUR GROLLMAN; Fiscal Year: 2007
    ..many years to explain the etiology of EN; we are pursuing an earlier, largely ignored and untested hypothesis that seeds of Aristolochia clemantitis contaminate grain used in baking bread, a dietary staple in the endemic region...
  39. Etiology of Balkan endemic nephropathy
    ARTHUR GROLLMAN; Fiscal Year: 2006
    ..many years to explain the etiology of EN; we are pursuing an earlier, largely ignored and untested hypothesis that seeds of Aristolochia clemantitis contaminate grain used in baking bread, a dietary staple in the endemic region...
  40. Fabrication and validation of implantable MRI markers for prostate cancer treatme
    Andrew Bright; Fiscal Year: 2010
    ..Prostate brachytherapy (PB) is performed using tiny radioactive (0.1-10 mCi) titanium seeds implanted directly into the prostate gland...
  41. A Novel Therapy for Staphylococcal Enterotoxin B Poisoning
    KENNETH PILLER; Fiscal Year: 2009
    ..Oral immunizations using soy milk formulations made from transgenic seeds expressing mutant SEB could elicit protective immunity in mice challenged with lethal doses of native toxin...
  42. Visualization and real-time dosimetry for prostate brachytherapy using ultrasound
    Septimiu Salcudean; Fiscal Year: 2007
    ..This treatment involves the permanent placement of radioactive capsules (seeds) in the prostate, in a pattern that delivers a sufficient radiation dose to kill the cancer while maintaining a ..
  43. Visualization and real-time dosimetry for prostate brachytherapy using ultrasound
    Septimiu Salcudean; Fiscal Year: 2006
    ..This treatment involves the permanent placement of radioactive capsules (seeds) in the prostate, in a pattern that delivers a sufficient radiation dose to kill the cancer while maintaining a ..
  44. Resolution of Gouty Inflammation
    STEPHEN MALAWISTA; Fiscal Year: 2007
    ..We hypothesize that early lipid mediators sow the seeds for later ones (lipoxins and perhaps novel moieties) with anti-inflammatory properties, leading to resolution...
  45. Molecular Mechanism of Genistein in Prostate Cancer
    Fazlul Sarkar; Fiscal Year: 2002
    ..The soy isoflavone, genistein is believed to be the primary anti-cancer agent found in whole grain cereal food, seeds and soybean products, which may play an important role in the prevention and/or treatment of human prostate cancer...
  46. Molecular Mechanism of Genistein in Prostate Cancer
    Fazlul Sarkar; Fiscal Year: 2004
    ..The soy isoflavone, genistein is believed to be the primary anti-cancer agent found in whole grain cereal food, seeds and soybean products, which may play an important role in the prevention and/or treatment of human prostate cancer...
  47. Molecular Mechanism of Genistein in Prostate Cancer
    Fazlul Sarkar; Fiscal Year: 2003
    ..The soy isoflavone, genistein is believed to be the primary anti-cancer agent found in whole grain cereal food, seeds and soybean products, which may play an important role in the prevention and/or treatment of human prostate cancer...
  48. Geography, networks, and risk in disease transmission
    Richard Rothenberg; Fiscal Year: 2009
    ..We will use ethnographic methods to identify 3 "seeds" in each of 5 high-burden and 5 low-burden zip codes, and will use a chain-link design to construct 30 networks of ..
  49. Geography, networks, and risk in disease transmission
    Richard Rothenberg; Fiscal Year: 2006
    ..We will use ethnographic methods to identify 3 "seeds" in each of 5 high-burden and 5 low-burden zip codes, and will use a chain-link design to construct 30 networks of ..
  50. Geography, networks, and risk in disease transmission
    Richard Rothenberg; Fiscal Year: 2007
    ..We will use ethnographic methods to identify 3 "seeds" in each of 5 high-burden and 5 low-burden zip codes, and will use a chain-link design to construct 30 networks of ..
  51. Geography, networks, and risk in disease transmission
    Richard Rothenberg; Fiscal Year: 2005
    ..We will use ethnographic methods to identify 3 "seeds" in each of 5 high-burden and 5 low-burden zip codes, and will use a chain-link design to construct 30 networks of ..
  52. Geography, networks, and risk in disease transmission
    Richard Rothenberg; Fiscal Year: 2009
    ..We will use ethnographic methods to identify 3 "seeds" in each of 5 high-burden and 5 low-burden zip codes, and will use a chain-link design to construct 30 networks of ..
  53. HIV and Substance Abuse Epidemiology among IDUs: Structural and Network Risk Fact
    ABBY ELISE RUDOLPH; Fiscal Year: 2012
    ..Sixteen "seeds" from 8 different colonias in Tijuana, Mexico will be selected from those recently enrolled in El Cuete to ..
  54. Recombinant Attenuated Salmonella Vaccines for Humans
    Roy Curtiss; Fiscal Year: 2009
    ..We will also add to our Master File (filed with FDA), prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  55. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2010
    ..Public Health Relevance: Permanent implantation of radioactive seeds containing iodine-125, palladium-103, or cesium-131 in the prostate, also called brachytherapy, has become a ..
  56. Prostate Edema in Permanent Interstitial Brachytherapy
    Zhe Chen; Fiscal Year: 2009
    ..Public Health Relevance: Permanent implantation of radioactive seeds containing iodine-125, palladium-103, or cesium-131 in the prostate, also called brachytherapy, has become a ..
  57. Recombinant Attenuated Salmonella Vaccines for Humans
    Roy Curtiss; Fiscal Year: 2010
    ..We will also add to our Master File (filed with FDA), prepare and fully characterize candidate vaccine Master Seeds for stability and safety, prepare and submit protocols for IRB approvals, submit information necessary to obtain ..
  58. PROTEIN-CARBOHYDRATE INTERACTION
    Irwin Goldstein; Fiscal Year: 1991
    ..Mucus from colon cancer will be fractionated on immobilized amaranthin, the lectin which we isolated and characterized from Amaranthus caudatus seeds. This lectin recognizes the T- or cryptic T-antigen [(NANAalpha2,3)Galbeta1,3GalNAc].
  59. PROTEIN-CARBOHYDRATE INTERACTION
    Irwin Goldstein; Fiscal Year: 1993
    ..Mucus from colon cancer will be fractionated on immobilized amaranthin, the lectin which we isolated and characterized from Amaranthus caudatus seeds. This lectin recognizes the T- or cryptic T-antigen [(NANAalpha2,3)Galbeta1,3GalNAc].
  60. Clinical Development of Combination Plague/Smallpox Vaccine
    CHARALAMBOS PARTIDOS; Fiscal Year: 2010
    ..pestis V antigen (MVA/V). We propose here to manufacture GMP-quality vaccine seeds and conduct preclinical studies required for FDA approval under the Animal Rule (21 CFR, 314...
  61. BREAST CANCER RISK--VEGETABLES AND SERUM PHYTOSTEROLS
    Paola Muti; Fiscal Year: 2000
    ..Phytosterols are abundant in fat soluble fractions of plants: seeds, nuts, cereals, beans, and legumes are rich sources of phytosterols...
  62. Pre-clinical Studies on Lupinus termis Seeds Extract
    MIKHAIL ANTOUN; Fiscal Year: 2002
    ..is intended to carry out preliminary pharmacology-toxicology studies on an alcoholic extract obtained form the seeds of a plant which, in earlier clinical studies performed outside the US, demonstrated encouraging activity in the ..
  63. PROTEIN-CARBOHYDRATE INTERACTION
    Irwin Goldstein; Fiscal Year: 1992
    ..Mucus from colon cancer will be fractionated on immobilized amaranthin, the lectin which we isolated and characterized from Amaranthus caudatus seeds. This lectin recognizes the T- or cryptic T-antigen [(NANAalpha2,3)Galbeta1,3GalNAc].
  64. Pre-clinical Studies on Lupinus termis Seeds Extract
    MIKHAIL ANTOUN; Fiscal Year: 2003
    ..is intended to carry out preliminary pharmacology-toxicology studies on an alcoholic extract obtained form the seeds of a plant which, in earlier clinical studies performed outside the US, demonstrated encouraging activity in the ..
  65. Clinical Development of Combination Plague/Smallpox Vaccine
    CHARALAMBOS PARTIDOS; Fiscal Year: 2009
    ..pestis V antigen (MVA/V). We propose here to manufacture GMP-quality vaccine seeds and conduct preclinical studies required for FDA approval under the Animal Rule (21 CFR, 314...
  66. Neurotoxicity of sterol glucosides: role in ALS-PDC
    Christopher Shaw; Fiscal Year: 2007
    ..complex (ALS-PDC) of Guam has been historically and experimentally associated with the consumption of seeds of the cycad palm known to contain various cyto- as well as specific neurotoxins...
  67. TRANSCRIPTIONAL CONTROL OF ARABIDOPSIS NITRATE REDUCTASE
    Chi Lien Cheng; Fiscal Year: 1991
    ..it self fertilizes to allow recessive mutants to be easily recovered, it is compact and produces large numbers of seeds, making large scale mutant screens feasible, it has a small genome size with very little repetitive DNA to ..
  68. Molecular Mechanism of Genistein in Prostate Cancer
    Fazlul Sarkar; Fiscal Year: 2001
    ..The soy isoflavone, genistein is believed to be the primary anti-cancer agent found in whole grain cereal food, seeds and soybean products, which may play an important role in the prevention and/or treatment of human prostate cancer...
  69. Gamma Ray Spectroscopy for Dose Rate Constants
    Ravinder Nath; Fiscal Year: 2004
    Permanent implantation of either iodine-125 seeds or palladium-103 radioactive seeds in the prostate has become a popular form of radiation therapy for carefully selected prostate cancer patients...
  70. Gamma Ray Spectroscopy for Dose Rate Constants
    Ravinder Nath; Fiscal Year: 2005
    Permanent implantation of either iodine-125 seeds or palladium-103 radioactive seeds in the prostate has become a popular form of radiation therapy for carefully selected prostate cancer patients...
  71. Gamma Ray Spectroscopy for Dose Rate Constants
    Ravinder Nath; Fiscal Year: 2006
    Permanent implantation of either iodine-125 seeds or palladium-103 radioactive seeds in the prostate has become a popular form of radiation therapy for carefully selected prostate cancer patients...