mining

Summary

Top Publications

  1. pmc Intellectual function in Mexican children living in a mining area and environmentally exposed to manganese
    Horacio Riojas-Rodriguez
    Dirección de Salud Ambiental, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
    Environ Health Perspect 118:1465-70. 2010
  2. doi Cause of death and presence of respiratory disease at autopsy in an HIV-1 seroconversion cohort of southern African gold miners
    Jill Murray
    National Institute for Occupational Health, PO Box 4788, Johannesburg2000, South Africa
    AIDS 21:S97-S104. 2007
  3. pmc Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010
    Carrie A Dooyema
    Healthy Homes and Lead Poisoning Prevention Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Environ Health Perspect 120:601-7. 2012
  4. pmc Metabolic diversity among main microorganisms inside an arsenic-rich ecosystem revealed by meta- and proteo-genomics
    Philippe N Bertin
    Genetique Moleculaire, Génomique et Microbiologie, UMR7156 CNRS and UdS, Strasbourg, France
    ISME J 5:1735-47. 2011
  5. pmc The diesel exhaust in miners study: I. Overview of the exposure assessment process
    Patricia A Stewart
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:728-46. 2010
  6. pmc Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study
    Patricia A Sullivan
    Field Studies Branch, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Environ Health Perspect 115:579-85. 2007
  7. doi Oscillating migration and the epidemics of silicosis, tuberculosis, and HIV infection in South African gold miners
    David Rees
    Occupational Medicine Division, National Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa
    Am J Ind Med 53:398-404. 2010
  8. doi Mining and other threats to the New Caledonia biodiversity hotspot
    Michel Pascal
    INRA, Station SCRIBE, Campus de Beaulieu, F 35 042 Rennes Cedex, France
    Conserv Biol 22:498-9. 2008
  9. pmc The Diesel Exhaust in Miners Study: II. Exposure monitoring surveys and development of exposure groups
    Joseph B Coble
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:747-61. 2010
  10. doi In situ evolutionary rate measurements show ecological success of recently emerged bacterial hybrids
    Vincent J Denef
    Department of Earth and Planetary Science, University of California, Berkeley, CA 94720, USA
    Science 336:462-6. 2012

Detail Information

Publications343 found, 100 shown here

  1. pmc Intellectual function in Mexican children living in a mining area and environmentally exposed to manganese
    Horacio Riojas-Rodriguez
    Dirección de Salud Ambiental, Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico
    Environ Health Perspect 118:1465-70. 2010
    ..Excessive exposure to manganese (Mn), an essential trace element, has been shown to be neurotoxic, especially when inhaled. Few studies have examined potential effects of Mn on cognitive functions of environmentally exposed children...
  2. doi Cause of death and presence of respiratory disease at autopsy in an HIV-1 seroconversion cohort of southern African gold miners
    Jill Murray
    National Institute for Occupational Health, PO Box 4788, Johannesburg2000, South Africa
    AIDS 21:S97-S104. 2007
    ..To describe causes of death and respiratory infections in HIV-infected miners in the pre-antiretroviral era, by duration of HIV infection...
  3. pmc Outbreak of fatal childhood lead poisoning related to artisanal gold mining in northwestern Nigeria, 2010
    Carrie A Dooyema
    Healthy Homes and Lead Poisoning Prevention Branch, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Environ Health Perspect 120:601-7. 2012
    ..In May 2010, a team of national and international organizations was assembled to investigate children's deaths due to lead poisoning in villages in northwestern Nigeria...
  4. pmc Metabolic diversity among main microorganisms inside an arsenic-rich ecosystem revealed by meta- and proteo-genomics
    Philippe N Bertin
    Genetique Moleculaire, Génomique et Microbiologie, UMR7156 CNRS and UdS, Strasbourg, France
    ISME J 5:1735-47. 2011
    ....
  5. pmc The diesel exhaust in miners study: I. Overview of the exposure assessment process
    Patricia A Stewart
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:728-46. 2010
    ..Air monitoring surveys at seven of the eight study mining facilities were conducted between 1998 and 2001 and provided reference personal REC exposure levels and ..
  6. pmc Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study
    Patricia A Sullivan
    Field Studies Branch, Division of Respiratory Disease Studies, National Institute for Occupational Safety and Health, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Environ Health Perspect 115:579-85. 2007
    ..Asbestos-contaminated Libby vermiculite was used in loose-fill attic insulation that remains in millions of homes in the United States, Canada, and other countries...
  7. doi Oscillating migration and the epidemics of silicosis, tuberculosis, and HIV infection in South African gold miners
    David Rees
    Occupational Medicine Division, National Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa
    Am J Ind Med 53:398-404. 2010
    ..This is termed oscillating or circular migration. Today we have serious interrelated epidemics of silicosis, tuberculosis, and HIV infection in the gold mining industry.
  8. doi Mining and other threats to the New Caledonia biodiversity hotspot
    Michel Pascal
    INRA, Station SCRIBE, Campus de Beaulieu, F 35 042 Rennes Cedex, France
    Conserv Biol 22:498-9. 2008
  9. pmc The Diesel Exhaust in Miners Study: II. Exposure monitoring surveys and development of exposure groups
    Joseph B Coble
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:747-61. 2010
    Air monitoring surveys were conducted between 1998 and 2001 at seven non-metal mining facilities to assess exposure to respirable elemental carbon (REC), a component of diesel exhaust (DE), for an epidemiologic study of miners exposed to ..
  10. doi In situ evolutionary rate measurements show ecological success of recently emerged bacterial hybrids
    Vincent J Denef
    Department of Earth and Planetary Science, University of California, Berkeley, CA 94720, USA
    Science 336:462-6. 2012
    ..The ecological success of hybrid bacterial types highlights the role of evolutionary processes in rapid adaptation within natural microbial communities...
  11. ncbi Mercury exposure and public health
    Jack C Clifton
    Great Lakes Center for Children s Environmental Health, John H Stroger, Jr Hospital of Cook County, Chicago, IL, USA
    Pediatr Clin North Am 54:237-69, viii. 2007
    ....
  12. ncbi The Mt. Diwata study on the Philippines 1999--assessing mercury intoxication of the population by small scale gold mining
    G Drasch
    Institute for Forensic Medicine, Ludwig Maximilians University, Munich, Germany
    Sci Total Environ 267:151-68. 2001
    ..A reduction of the external Hg burden on Mt. Diwata is urgently recommended. An attempt to treat the intoxicated participants with the chelating agent dimercaptopropanesulfonic acid (DMPS) is planned...
  13. pmc The Diesel Exhaust in Miners Study: IV. Estimating historical exposures to diesel exhaust in underground non-metal mining facilities
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:774-88. 2010
    ..for an epidemiologic study of mortality, including lung cancer, among diesel-exposed miners at eight non-metal mining facilities [the Diesel Exhaust in Miners Study (DEMS)]...
  14. pmc Mercury exposure, serum antinuclear/antinucleolar antibodies, and serum cytokine levels in mining populations in Amazonian Brazil: a cross-sectional study
    Renee M Gardner
    Johns Hopkins Bloomberg School of Public Health, Department of Environmental Health Sciences, Baltimore, MD 21205, USA
    Environ Res 110:345-54. 2010
    ..We have reported elevated levels of ANA and ANoA in human populations exposed to mercury in artisanal gold mining, though other confounding variables that may also modulate ANA/ANoA levels were not well controlled...
  15. pmc Characterization of Ferroplasma isolates and Ferroplasma acidarmanus sp. nov., extreme acidophiles from acid mine drainage and industrial bioleaching environments
    Mark Dopson
    School of Biological Sciences Centre for Ecology, Evolution and Conservation, University of East Anglia, Norwich NR4 7TJ, United Kingdom
    Appl Environ Microbiol 70:2079-88. 2004
    ..F. acidarmanus" Fer1(T) groups separately, and we propose the new species "F. acidarmanus" Fer1(T) sp. nov...
  16. ncbi An archaeal iron-oxidizing extreme acidophile important in acid mine drainage
    K J Edwards
    Department of Geology and Geophysics, University of Wisconsin Madison, 1215 West Dayton Street, Madison, WI 53706, USA
    Science 287:1796-9. 2000
    ..The presence of this and other closely related Thermoplasmales suggests that these acidophiles are important contributors to acid mine drainage and may substantially impact iron and sulfur cycles...
  17. ncbi Health assessment of artisanal gold miners in Indonesia
    Stephan Bose-O'Reilly
    Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT University for Health Sciences, Medical Informatics and Technology, Eduard Wallnoefer Center I, A 6060 Hall i T, Austria
    Sci Total Environ 408:713-25. 2010
    ..Less exposed mineral processors and the general population in the mining areas were also intoxicated to a high percentage.
  18. ncbi Comparison of ferric iron generation by different species of acidophilic bacteria immobilized in packed-bed reactors
    Owen F Rowe
    School of Biological Sciences, University of Wales, Bangor LL57 4UF, UK
    Syst Appl Microbiol 31:68-77. 2008
    ....
  19. doi Biodiversity and geochemistry of an extremely acidic, low-temperature subterranean environment sustained by chemolithotrophy
    Sakurako Kimura
    School of Biological Sciences, College of Natural Sciences, Bangor University, Deiniol Road, Bangor, LL57 2UW, UK
    Environ Microbiol 13:2092-104. 2011
    ..ferrivorans and acidophilic iron-oxidizing Betaproteobacteria) in mediating mineral oxidation and redox transformations of iron in acidic, low-temperature environments...
  20. pmc GeoChip-based analysis of the functional gene diversity and metabolic potential of microbial communities in acid mine drainage
    Jianping Xie
    School of Mineral Processing and Bioengineering, Central South University, Changsha, Hunan 410083, China
    Appl Environ Microbiol 77:991-9. 2011
    ..This study presents an overview of functional gene diversity and the structure of AMD microbial communities and also provides insights into our understanding of metabolic potential in AMD ecosystems...
  21. ncbi Ecology. Danger of deep-sea mining
    Jochen Halfar
    Department of Chemical and Physical Sciences, University of Toronto at Mississauga, Mississauga, Ontario, Canada, L5L 1C6
    Science 316:987. 2007
  22. ncbi The Mt. Diwata study on the Philippines 2000-treatment of mercury intoxicated inhabitants of a gold mining area with DMPS (2,3-dimercapto-1-propane-sulfonic acid, Dimaval)
    S Bose-O'Reilly
    Institute of Forensic Medicine, Ludwig Maximilians University, Munich, Germany
    Sci Total Environ 307:71-82. 2003
    Ninty-five inhabitants of the gold mining area of Mt. Diwata (on Mindanao, Philippines), who were diagnosed to be mercury (Hg) intoxicated, were orally treated with 2 x 200 mg of the chelating agent DMPS (Dimaval, Co...
  23. doi The influence of radon exposures on lung cancer mortality in German uranium miners, 1946-2003
    Linda Walsh
    Federal Office for Radiation Protection, Department Radiation Protection and Health, 85764 Oberschleissheim, Germany
    Radiat Res 173:79-90. 2010
    Extensive uranium extraction took place from 1946 until 1990 at the former Wismut mining company in East Germany...
  24. doi Copper mining in Streptomyces: enzymes, natural products and development
    Jonathan A R Worrall
    Department of Biological Sciences, University of Essex, Colchester, CO4 3SQ, UK
    Nat Prod Rep 27:742-56. 2010
    ....
  25. ncbi High human exposure to cobalt and other metals in Katanga, a mining area of the Democratic Republic of Congo
    Célestin Lubaba Nkulu Banza
    Unité de Toxicologie et Environnement, Ecole de Santé Publique, Université de Lubumbashi, Democratic Republic of Congo
    Environ Res 109:745-52. 2009
    The human health impact of the historic and current mining and processing of non-ferrous metals in the African Copperbelt is not known...
  26. doi Decreases in depression over 20 years in a mining area of Sardinia: due to selective migration?
    Mauro Giovanni Carta
    Centro di Psichiatria di Consultazione e Psicosomatica, Azienda Ospedaliero Universitaria di Cagliari, University of Cagliari, Italy
    J Affect Disord 141:255-60. 2012
    ..The objective of the study was to determine if community surveys, conducted 3 times over a period of 20 years in a small district of Sardinia (Italy), confirm the increase in depressive disorders reported in the recent literature...
  27. ncbi Contamination status of arsenic and other trace elements in drinking water and residents from Tarkwa, a historic mining township in Ghana
    Kwadwo Ansong Asante
    Center for Marine Environmental Studies, Ehime University, Bunkyo cho 2 5, Matsuyama, Ehime 790 8577, Japan
    Chemosphere 66:1513-22. 2007
    ..assess the contamination status of 22 trace elements, especially As in water and residents in Tarkwa, a historic mining town in Ghana...
  28. ncbi Retrospective exposure assessment for respirable and inhalable dust, crystalline silica and arsenic in the former German uranium mines of SAG/SDAG Wismut
    D Dahmann
    Institut für Gefahrstoff Forschung, IGF, Bochum, Germany
    Int Arch Occup Environ Health 81:949-58. 2008
    ..to the end of the 1990s, an extensive series of retrospective exposure investigations for the East German uranium mining industry was performed in order to provide information about the exposure situation of the miners towards ..
  29. ncbi Community proteomics of a natural microbial biofilm
    Rachna J Ram
    Department of Environmental Science, Policy, and Management, University of California at Berkeley, Berkeley, CA 94720, USA
    Science 308:1915-20. 2005
    ..We validated and estimated the relative abundance and cellular localization of 357 unique and 215 conserved novel proteins and determined that one abundant novel protein is a cytochrome central to iron oxidation and AMD formation...
  30. ncbi Role of methylmercury exposure (from fish consumption) on growth and neurodevelopment of children under 5 years of age living in a transitioning (tin-mining) area of the western Amazon, Brazil
    Rejane C Marques
    Escola de Enfermagem Anna Nery, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil
    Arch Environ Contam Toxicol 62:341-50. 2012
    Human occupation of the Amazon region has recently increased, bringing deforestation for agriculture and open-cast mining, activities that cause environmental degradation and pollution...
  31. ncbi Cultivation-dependent and cultivation-independent characterization of the microbial community in acid mine drainage associated with acidic Pb/Zn mine tailings at Lechang, Guangdong, China
    Gui Liang Tan
    State Key Laboratory of Biocontrol, School of Life Sciences, University of Wales, UK
    FEMS Microbiol Ecol 59:118-26. 2007
    ..Thus, the present study extends our knowledge of the biodiversity of microorganisms populating highly acidic AMD environments...
  32. doi Sleep and circadian rhythms in mining operators: limited evidence of adaptation to night shifts
    Sally A Ferguson
    Centre for Sleep Research, University of South Australia, Australia
    Appl Ergon 43:695-701. 2012
    ..The current study followed twenty-nine operators at a live-in mining operation working to a seven-day, seven-night shift pattern who collected saliva samples for melatonin measurement,..
  33. ncbi HIV/AIDS prevalence testing--merits, methodology and outcomes of a survey conducted at a large mining organisation in South Africa
    W Stevens
    Department of Molecular Medicine and Haematology, University of the Witwatersrand, Johannesburg
    S Afr Med J 96:134-9. 2006
    ..To determine the HIV prevalence rate at Anglo Platinum, a large, multinational organisation operating in South Africa (Gauteng, Limpopo and North-West), and to assess the merits, methodology and outcomes of the survey...
  34. pmc In situ proteo-metabolomics reveals metabolite secretion by the acid mine drainage bio-indicator, Euglena mutabilis
    David Halter
    UMR7156 Université de Strasbourg CNRS, Genetique Moleculaire, Génomique et Microbiologie, Département Micro organismes, Génomes, Environnement, Strasbourg, France
    ISME J 6:1391-402. 2012
    ..mutabilis. Consequently, this protist may have an indirect but important role in AMD ecosystems but also in other ecological niches often described as nitrogen-limited...
  35. ncbi Ischemic heart disease mortality among miners and other potentially silica-exposed workers
    Jan Weiner
    Swedish Work Environment Authority, Solna, Sweden
    Am J Ind Med 50:403-8. 2007
    ..Some previous studies have observed an increased mortality regarding ischemic heart disease (IHD) among miners and industrial sand workers. The purpose was to study the occurrence of IHD mortality among silica-exposed workers...
  36. ncbi South African experience with asbestos related environmental mesothelioma: is asbestos fiber type important?
    Neil White
    UCT Lung Institute and Department of Medicine, University of Cape Town, P O Box 34560, Groote Schuur 7937, South Africa
    Regul Toxicol Pharmacol 52:S92-6. 2008
    ..In the vast majority of these cases, exposure was linked to crocidolite mining activities in the Northern Cape Province...
  37. pmc Incidence of leukemia, lymphoma, and multiple myeloma in Czech uranium miners: a case-cohort study
    Vladimír Rericha
    Health Institute of the Uranium Industry, Príbram, Czech Republic
    Environ Health Perspect 114:818-22. 2006
    ..Uranium miners are chronically exposed to low levels of radon and its progeny. We investigated whether radon exposure is associated with increased incidence of leukemia, lymphoma, or multiple myeloma in this population...
  38. ncbi Evaluation of genotoxic effects of heavy metals and arsenic in wild nestling white storks (Ciconia ciconia) and black kites (Milvus migrans) from southwestern Spain after a mining accident
    Raquel Baos
    Department of Applied Biology, Estación Biológica de Doñana C S I C, Avda Ma Luisa s n Pabellón del Perú, 41013 Sevilla, Spain
    Environ Toxicol Chem 25:2794-803. 2006
    Studies of birds from Doñana (southwestern Spain) after the Aznalcóllar mining accident (April 1998) have reported high levels of genetic damage when compared to conspecifics from reference areas...
  39. ncbi Heavy metal pollution of soils affected by the Guadiamar toxic flood
    F Cabrera
    Instituto de Recursos Naturales y Agrobiología de Sevilla CSIC, Spain
    Sci Total Environ 242:117-29. 1999
    ....
  40. pmc Gold mining in the Peruvian Amazon: global prices, deforestation, and mercury imports
    Jennifer J Swenson
    Nicholas School of the Environment, Duke University, Durham, North Carolina, United States of America
    PLoS ONE 6:e18875. 2011
    ..We find that since 2003, recent mining deforestation in Madre de Dios, Peru is increasing nonlinearly alongside a constant annual rate of increase in ..
  41. ncbi HIV and STIs in clients and female sex workers in mining regions of Gejiu City, China
    Jun Jie Xu
    National Center for AIDS STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China
    Sex Transm Dis 35:558-65. 2008
    To investigate HIV/sexually transmitted infections (STIs) among female sex workers (FSWs) and clients in a mining region of China.
  42. ncbi Use of fluoroquinolone antibiotics leads to tuberculosis treatment delay in a South African gold mining community
    C Y Jeon
    Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Int J Tuberc Lung Dis 15:77-83. 2011
    ..Empiric use of fluoroquinolone (FQ) antibiotics could delay tuberculosis (TB) treatment and lead to FQ-resistant TB...
  43. pmc Community-level social support responses in a slow-motion technological disaster: the case of Libby, Montana
    Rebecca J W Cline
    School of Communication Studies, Kent State University, Kent, OH 44242, USA
    Am J Community Psychol 46:1-18. 2010
    ..Specifically, community-level conflict appears to interfere with previously established social support patterns. The observed phenomenon can be understood as the deterioration of a previously supportive community...
  44. ncbi Use of the modified BCR three-step sequential extraction procedure for the study of trace element dynamics in contaminated soils
    M Pueyo
    Departament de Quimica Analitica, Universitat de Barcelona, Marti i Franques 1 11, E 08028 Barcelona, Spain
    Environ Pollut 152:330-41. 2008
    ..Thus, the effectiveness of the BCR procedure has proved to be a useful tool for predicting short- and long-term mobility of trace elements, even in complex environmental scenarios...
  45. ncbi Factors associated with an increased case-fatality rate in HIV-infected and non-infected South African gold miners with pulmonary tuberculosis
    G J Churchyard
    Aurum Health Research, Welkom, Free State, South Africa
    Int J Tuberc Lung Dis 4:705-12. 2000
    A gold mining company in the Free State Province, South Africa.
  46. ncbi Microbial diversity in uranium mining-impacted soils as revealed by high-density 16S microarray and clone library
    Gurdeep Rastogi
    Department of Chemical and Biological Engineering, South Dakota School of Mines and Technology, Rapid City, SD 57701, USA
    Microb Ecol 59:94-108. 2010
    Microbial diversity was characterized in mining-impacted soils collected from two abandoned uranium mine sites, the Edgemont and the North Cave Hills, South Dakota, using a high-density 16S microarray (PhyloChip) and clone libraries...
  47. ncbi Estimating historical respirable crystalline silica exposures for Chinese pottery workers and iron/copper, tin, and tungsten miners
    Z Zhuang
    National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, US Department of Health and Human Services, 1095 Willowdale Road, Morgantown, WV 26505, USA
    Ann Occup Hyg 45:631-42. 2001
    ..The exposure matrix of the historical Chinese total dust concentrations was multiplied by these conversion factors to obtain an exposure matrix of historical respirable crystalline silica concentrations...
  48. pmc The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilities
    Roel Vermeulen
    Division of Cancer Epidemiology and Genetics, US National Cancer Institute, Bethesda, MD 20892, USA
    Ann Occup Hyg 54:762-73. 2010
    ..historical components of DE from side-by-side area measurements taken in underground operations of seven non-metal mining facilities...
  49. pmc Behavioural development of school-aged children who live around a multi-metal sulphide mine in Guangdong province, China: a cross-sectional study
    Qing Song Bao
    Department of Food Safe Supervision, Health Inspection and Supervision Center, 205 Renmin South Road, Yixing, PR China
    BMC Public Health 9:217. 2009
    ..The present study aimed to estimate relationships between measured multi-metal exposures and the presence of behavioural problems for the school-aged children in the polluted area...
  50. ncbi Effect of HIV on work-related injury rates in South African gold miners
    Jill Murray
    National Institute for Occupational Health, National Health Laboratory Service, Johannesburg, South Africa
    AIDS 19:2019-24. 2005
    ..The objective was to calculate the effect of HIV on the rate and severity of work-related injuries by duration of infection...
  51. ncbi Inorganic carbon limitation and mixotrophic growth in Chlamydomonas from an acidic mining lake
    Jörg Tittel
    Institute of Biochemistry and Biology, University of Potsdam, Maulbeerallee 2, 14469 Potsdam, Germany
    Protist 156:63-75. 2005
    Plankton communities in acidic mining lakes (pH 2.5-3.3) are species-poor because they face extreme environmental conditions, e.g. 150mg l(-1) Fe2+ +Fe3+...
  52. doi Incidence of tuberculosis and HIV and progression of silicosis and lung function impairment among former Basotho gold miners
    Harriet H Park
    International AIDS Vaccine Initiative, New York, New York, USA
    Am J Ind Med 52:901-8. 2009
    ..Pulmonary tuberculosis and HIV incidence, mortality, and the progression of silicosis and lung function impairment are described over a 1-year period in migrant ex-gold miners from Lesotho...
  53. ncbi Heavy metal mining using microbes
    Douglas E Rawlings
    Department of Microbiology, University of Stellenbosch, Private Bag X1, South Africa
    Annu Rev Microbiol 56:65-91. 2002
    ..The development of higher-temperature processes will extend the variety of minerals that can be commercially processed...
  54. pmc Methylmercury neurotoxicity in Amazonian children downstream from gold mining
    P Grandjean
    Department of Environmental Medicine, Odense University, Odense, Denmark
    Environ Health Perspect 107:587-91. 1999
    In widespread informal gold mining in the Amazon Basin, mercury is used to capture the gold particles as amalgam. Releases of mercury to the environment have resulted in the contamination of freshwater fish with methylmercury...
  55. ncbi A review of the federal government's health activities in response to asbestos-contaminated ore found in Libby, Montana
    Kevin Horton
    Agency for Toxic Substances and Disease Registry, Division of Health Studies, Surveillance and Registries Branch, Atlanta, Georgia 30333, USA
    Inhal Toxicol 18:925-40. 2006
    ..This article presents the various follow-up activities that have been conducted to date by ATSDR and partnering state health departments...
  56. ncbi Determinants of reproductive health and related quality of life among Indian women in mining communities
    Melba Sheila D'Souza
    Department of Adult Health and Critical Care, Sultan Qaboos University, Muscat, Sultanate of Oman
    J Adv Nurs 67:1963-75. 2011
    ..This article is a report of a mixed method to examine the determinants of reproductive health and quality of life among Indian women...
  57. ncbi High percentage inorganic arsenic content of mining impacted and nonimpacted Chinese rice
    Y G Zhu
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China
    Environ Sci Technol 42:5008-13. 2008
    ..Two of the sites were within mining and smeltery districts, and the third was devoid of large-scale metal processing industries...
  58. pmc Exposure to silica and silicosis among tin miners in China: exposure-response analyses and risk assessment
    W Chen
    Department of Labor Health and Occupational Diseases, School of Public Health, Tonji Medical University, 13 Hang Kong Lu, Wuhan, Hubei, People s Republic of China
    Occup Environ Med 58:31-7. 2001
    ..To investigate the risk of silicosis among tin miners and to investigate the relation between silicosis and cumulative exposure to dust (Chinese total dust and respirable crystalline silica dust)...
  59. ncbi Prevalence of occupational lung disease in a random sample of former mineworkers, Libode District, Eastern Cape Province, South Africa
    A S Trapido
    Epidemiology Research Unit, Johannesburg, South Africa
    Am J Ind Med 34:305-13. 1998
    ..Gold mineworkers in South Africa are exposed to high levels of silica dust as a result of which they are at risk of developing silicosis, which is a compensable disease. The incidence of tuberculosis is also high...
  60. doi Impact of biostimulated redox processes on metal dynamics in an iron-rich creek soil of a former uranium mining area
    Eva Maria Burkhardt
    Institute of Ecology, Friedrich Schiller University Jena, Dornburger Strabetae 159, D 07743 Jena, Germany
    Environ Sci Technol 44:177-83. 2010
    ..An iron-rich creek soil of a former uranium-mining district (Ronneburg, Germany) showed high porewater concentrations of heavy metals and radionuclides...
  61. ncbi Radon, smoking and lung cancer risk: results of a joint analysis of three European case-control studies among uranium miners
    Klervi Leuraud
    Institute for Radiological Protection and Nuclear Safety, B P 17, F 92262 Fontenay aux Roses Cedex, France
    Radiat Res 176:375-87. 2011
    ..The results confirm that the lung carcinogenic effect of radon persists even when smoking is adjusted for, with arguments in favor of a sub-multiplicative interaction between radon and smoking...
  62. ncbi HIV infection and silicosis: the impact of two potent risk factors on the incidence of mycobacterial disease in South African miners
    E L Corbett
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, UK
    AIDS 14:2759-68. 2000
    ..To investigate the combined effects of HIV infection and silicosis on mycobacterial disease...
  63. ncbi Changing patterns of knowledge, reported behaviour and sexually transmitted infections in a South African gold mining community
    Brian G Williams
    16 rue de la Canonniere, Geneva 1202, Switzerland
    AIDS 17:2099-107. 2003
    In 1998, a major HIV intervention project was started in a mining community in Carletonville, South Africa...
  64. ncbi Mercury exposures and symptoms in smelting workers of artisanal mercury mines in Wuchuan, Guizhou, China
    Ping Li
    State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, 46 Guanshui Road, Guiyang 550002, China
    Environ Res 107:108-14. 2008
    ..Clinical symptoms including finger and eyelid tremor, gingivitis, and typical dark-line on gums were observed in six workers. This study indicated that the smelting workers in Wuchuan were seriously exposed to mercury vapor...
  65. doi Baseline study of the spatio-temporal patterns of reef fish assemblages prior to a major mining project in New Caledonia (South Pacific)
    Pascale Chabanet
    IRD, UR 128, BP 172, 97492 Ste Clotilde cedex, La Reunion, France
    Mar Pollut Bull 61:598-611. 2010
    ..These results are discussed and compared with others sites of the South Pacific. For monitoring perspectives, some indicators related to expected disturbances are proposed...
  66. ncbi Mortality of former crocidolite (blue asbestos) miners and millers at Wittenoom
    A W Musk
    Occupational Respiratory Epidemiology, School of Population Health, M431, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia
    Occup Environ Med 65:541-3. 2008
    ..Blue asbestos was mined and milled at Wittenoom in Western Australia between 1943 and 1966...
  67. ncbi Accumulation of Pb, Cd, Cu and Zn in plants and hyperaccumulator choice in Lanping lead-zinc mine area, China
    Zu Yanqun
    Eco environment Research Institute, College of Resources and Environment, Yunnan Agricultural University, Kunming 650201, PR China
    Environ Int 30:567-76. 2004
    ..annae in Paomaping, had high accumulation capacity. R. annae in Paomaping had hyperaccumulating capacity to Pb, Cd and Zn, L. plyneura to Pb and Cd, and S. cathayana to Cd, respectively...
  68. ncbi Influence of a mine tailing accident near Doñana National Park (Spain) on heavy metals and arsenic accumulation in 14 species of waterfowl (1998 to 2000)
    G Gomez
    Department of Instrumental Analysis and Environmental Chemistry, Instituto Química Orgánica General, Consejo Superior de Investigaciones Cientificas, Juan de la Cierva 3, 28006 Madrid, Spain
    Arch Environ Contam Toxicol 47:521-9. 2004
    ..Four species (Anser anser, Ciconia ciconia, Larus ridibundus, and Porphyrio porphyrio) were found to have the highest levels of the 5 elements...
  69. pmc Radon and risk of extrapulmonary cancers: results of the German uranium miners' cohort study, 1960-2003
    M Kreuzer
    Federal Office for Radiation Protection, Department of Radiation Protection and Health, Neuherberg 85764, Germany
    Br J Cancer 99:1946-53. 2008
    ..cohort includes 58,987 men who were employed for at least 6 months from 1946 to 1989 at the former Wismut uranium mining company in Eastern Germany. A total of 20,684 deaths were observed in the follow-up period from 1960 to 2003...
  70. ncbi Mercury in surface soil and cassava crop near an alluvial goldmine at Dunkwa-on-Offin, Ghana
    A A Golow
    Department of Chemistry, University of Cape Coast, Cape Coast, Ghana
    Bull Environ Contam Toxicol 69:228-35. 2002
  71. ncbi Health assessment of artisanal gold miners in Tanzania
    Stephan Bose-O'Reilly
    Institute of Public Health, Medical Decision Making and Health Technology Assessment, UMIT University for Health Sciences, Medical Informatics and Technology, Eduard Wallnoefer Center I, A 6060 Hall i T, Austria
    Sci Total Environ 408:796-805. 2010
    ..Nations Industrial Development Organization) conducted an environmental and health assessment in a small-scale mining area in Tanzania. BGS (British Geological Survey) performed the environmental assessment...
  72. pmc Spatial and temporal analysis of the microbial community in the tailings of a Pb-Zn mine generating acidic drainage
    Li Nan Huang
    Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, Sun Yat Sen Zhongshan University, Guangzhou 510275, People s Republic of China
    Appl Environ Microbiol 77:5540-4. 2011
    ..were consistently present in the acidic tailings, acidophilic archaea, mostly Ferroplasma acidiphilum, were predominant in the oxidized zones and the oxidation front, indicating their importance to generation of acid mine drainage...
  73. ncbi Characterisation of sequential leachate discharges of mining waste rock dumps in the Tinto and Odiel rivers
    A Sainz
    Departamento de Ciencias Agroforestales, Area de Tecnología del Medio Ambiente, Universidad de Huelva, 21819 Palos de la Frontera, Huelva, Spain
    J Environ Manage 64:345-53. 2002
    b>Mining waste rock dumps (WRDs) are potential sources of pollution, which after rainfall produce leachate discharges, loaded with acid mining drainage (AMD)...
  74. ncbi Multiple factor design for reactive mixture selection for use in reactive walls in mine drainage treatment
    Ioana A Cocos
    Ecole Polytechnique de Montreal, Quebec, Canada
    Water Res 36:167-77. 2002
    ..86, F = 62.38 (p-level < 10(-13)) and R2 = 0.90. F = 62.30 (p-level < 10(-13))) identified poultry manure and two other carbon sources as the critical variables for sulfate-reduction rate...
  75. ncbi Use of conductivity to monitor the treatment of acid mine drainage by sulphate-reducing bacteria
    D Lyew
    Department of Agricultural and Biosystems Engineering, Macdonald Campus of McGill University, 21111 Lakeshore Road, Ste Anne-de-Bellevue, Quebec, Canada H9X 3V9
    Water Res 35:2081-6. 2001
    ..Changes in conductivity were not always coincident with changes in ORP and pH, indicating that conductivity may be a more sensitive tool for locating and monitoring specific zones of SRB activity...
  76. doi Ecological impacts of lead mining on Ozark streams: toxicity of sediment and pore water
    John M Besser
    US Geological Survey, Columbia Environmental Research Center, 4200 New Haven Road, Columbia, MO 65201, USA
    Ecotoxicol Environ Saf 72:516-26. 2009
    We studied the toxicity of sediments downstream of lead-zinc mining areas in southeast Missouri, using chronic sediment toxicity tests with the amphipod, Hyalella azteca, and pore-water toxicity tests with the daphnid, Ceriodaphnia dubia...
  77. doi Technological assessment of a mining-waste dump at the Dexing copper mine, China, for possible conversion to an in situ bioleaching operation
    Aixiang Wu
    School of Civil and Environment Engineering, University of Science and Technology Beijing, Beijing 100083, China
    Bioresour Technol 100:1931-6. 2009
    ..To evaluate the potential unstability of the dump, the leaching process, ore surface erosion, particle size, chemical elements and mechanical properties of the waste rock in DCM were investigated through experiment in this paper...
  78. ncbi Water chemistry and ecotoxicity of an acid mine drainage-affected stream in subtropical China during a major flood event
    C Lin
    Centre for Ecological and Environmental Technologies, South China Agricultural University, Guangzhou 510642, China
    J Hazard Mater 142:199-207. 2007
    ..5 km downstream of the discharge point was highly toxic to the test organism. At 25 km downstream of the discharge point where stream water pH was as high as 5.75, marked toxic responses of the test organism were still observed...
  79. doi The impact of mining activities in alteration of As levels in the surrounding ecosystems: an encompassing risk assessment and evaluation of remediation strategies
    Janice Susaya
    Department of Environment and Energy, Sejong University, 98 Goon Ja Dong, Seoul 143 747, Republic of Korea
    J Hazard Mater 182:427-38. 2010
    ..69 mg kg(-1)) and the strong correlation between TS and TA) suggests a strong effect of previous mining activities...
  80. ncbi Could the bug Triatoma sherlocki be vectoring Chagas disease in small mining communities in Bahia, Brazil?
    C E Almeida
    Laboratório de Biodiversidade Entomológica, Instituto Oswaldo Cruz FIOCRUZ IOC Fiocruz, Rio de Janeiro, Brazil
    Med Vet Entomol 23:410-7. 2009
    ..was described in the municipality of Gentio do Ouro, in the state of Bahia, Brazil, and in a small artisan quarry-mining community approximately 13 km distant in a remote area of the same municipality...
  81. ncbi Soil to plant transfer of 238U, 226Ra and 232Th on a uranium mining-impacted soil from southeastern China
    S B Chen
    Research Center for Eco Environmental Sciences, Chinese Academy of Sciences, 18 Shuangqing Road, Beijing 100085, PR China
    J Environ Radioact 82:223-36. 2005
    ..3+/-1.2) and 232Th (5.3+/-1.7), while the smallest R/S ratio for 238U was observed in clover (2.8+/-0.9)...
  82. ncbi Arsenic hazards to humans, plants, and animals from gold mining
    Ronald Eisler
    U S Geological Survey, Patuxent Wildlife Research Center, 11510 American Holly Drive, Laurel, MD 20708 4019, USA
    Rev Environ Contam Toxicol 180:133-65. 2004
    Arsenic sources to the biosphere associated with gold mining include waste soil and rocks, residual water from ore concentrations, roasting of some types of gold-containing ores to remove sulfur and sulfur oxides, and bacterially enhanced ..
  83. ncbi Long-term effects of the Aznalcóllar mine spill-heavy metal content and mobility in soils and sediments of the Guadiamar river valley (SW Spain)
    Uta Kraus
    Faculty Biology and Geography, University of Duisburg Essen, Universitaetsstrasse 2, 45141 Essen, Germany
    Sci Total Environ 367:855-71. 2006
    ..As a consequence of the heavy metal migration, an accumulation zone has formed up to 30 cm into the underlying soil at the time of investigation. In the future, there may be further penetration of heavy metals to greater depths...
  84. ncbi Oxidation of arsenite by Thiomonas strains and characterization of Thiomonas arsenivorans sp. nov
    Fabienne Battaglia-Brunet
    BRGM, Environment and Process Division, Biotechnology Unit, 2 av Claude Guillemin, 45060, Orléans cedex 02, France
    Antonie Van Leeuwenhoek 89:99-108. 2006
    ..It was closely related to an unnamed Thiomonas strain (NO115) isolated from a Norwegian mining site, though sequence identities between strain b6(T) and characterized Thiomonas species were less than 95%...
  85. ncbi Hyperaccumulation of Pb, Zn and Cd in herbaceous grown on lead-zinc mining area in Yunnan, China
    Zu Yanqun
    Eco environment Research Institute, College of Resources and Environment, Yunnan Agricultural University, Kunming 650201, P R China
    Environ Int 31:755-62. 2005
    A field survey of herbaceous growing on lead-zinc mining area in Yunnan, China were conducted to identify species accumulating exceptionally large concentrations of Pb, Zn and Cd in shoots...
  86. ncbi Exposures to silica mixed dust and cohort mortality study in tin mines: exposure-response analysis and risk assessment of lung cancer
    Weihong Chen
    Department of Occupational and Environmental Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China
    Am J Ind Med 49:67-76. 2006
    ..The health impacts on workers with silica mixed dust exposure in tin mines and dose-response relationships between cumulative dust exposure and the mortality from lung cancer are investigated...
  87. ncbi Biosorption of metal and salt tolerant microbial isolates from a former uranium mining area. Their impact on changes in rare earth element patterns in acid mine drainage
    Götz Haferburg
    Friedrich Schiller University, Institute of Microbiology, Jena, Germany
    J Basic Microbiol 47:474-84. 2007
    The concentration of metals in microbial habitats influenced by mining operations can reach enormous values...
  88. ncbi Feasibility and acceptability of a specialist clinical service for HIV-infected mineworkers in South Africa
    S Charalambous
    Aurum Health Research, Welkom, South Africa
    AIDS Care 16:47-56. 2004
    ..A specialized clinic was established in a mining hospital in the Free State, South Africa, with the primary aim of delivering preventive therapy such as isoniazid ..
  89. ncbi Sequential extraction of heavy metals in river sediments of an abandoned pyrite mining area: pollution detection and affinity series
    F Pagnanelli
    Department of Chemistry, University of Rome La Sapienza, p le A Moro, 5, 00185 Rome, Italy
    Environ Pollut 132:189-201. 2004
    ....
  90. ncbi Cyanide hazards to plants and animals from gold mining and related water issues
    Ronald Eisler
    US Geological Survey, Patuxent Wildlife Research Center, 11510 American Holly Drive, Laurel, Maryland 20708 4019, USA
    Rev Environ Contam Toxicol 183:21-54. 2004
    ..Surface waters are diverted around surface mining operations...
  91. ncbi Initial studies for the phytostabilization of a mine tailing from the Cartagena-La Union Mining District (SE Spain)
    Héctor M Conesa
    Soil Protection Group, Institute of Terrestrial Ecology, Swiss Federal Institute of Technology, ETH Zurich, Universitatstrasse 16, CH 8092 Zurich, Switzerland
    Chemosphere 66:38-44. 2007
    Mine tailings are one of the main environmental problems in post-mining landscapes and their removal is often complicated due to their high heavy metal content and dimensions...
  92. ncbi Trace element partitioning and soil particle characterisation around mining and smelting areas at Tharsis, Ríotinto and Huelva, SW Spain
    E I B Chopin
    School of Human and Environmental Sciences, University of Reading, UK
    Sci Total Environ 373:488-500. 2007
    Trace elements may present an environmental hazard in the vicinity of mining and smelting activities...
  93. ncbi Evolution of biological effects of Aznalcóllar mining spill in the Algerian mouse (Mus spretus) using biochemical biomarkers
    D Bonilla-Valverde
    Department of Biochemistry and Molecular Biology, University of Cordoba, Severo Ochoa Building, 2nd Floor, Campus of Rabanales, Road N IV, Km 396a, 14071 Cordoba, Spain
    Toxicology 197:123-38. 2004
    ..The increasing responses of several biomarkers at reference sites may suggest a progressive pollution of key Doñana ecosystems...
  94. ncbi [Association between reported annual gold mining extraction and incidence of malaria in Mato Grosso-Brazil, 1985-1996]
    Elisabeth Carmen Duarte
    Fundacao Nacional de Saude, Cuiaba, MT, Brasil
    Rev Soc Bras Med Trop 35:665-8. 2002
    ..ecological design to study the association between malaria incidence rates, the reported annual production of gold mining extraction and monetary investments for the control of malaria from 1985 to 1996 in Mato Grosso, Brazil...
  95. ncbi Health and environmental assessment of mercury exposure in a gold mining community in Western Mindanao, Philippines
    Nelia Cortes-Maramba
    National Poison Control and Information Service, College of Medicine, University of the Philippines Manila, Philippines
    J Environ Manage 81:126-34. 2006
    The small-scale gold mining activities using mercury began in the late 1980s in Sibutad, Western Mindanao. It is located very near the Murcielagos Bay with tailing ponds directly discharging into bodies of water...
  96. pmc HIV-1 and STIs prevalence and risk factors of miners in mining districts of Yunnan, China
    Guolei Zhang
    National Center for AIDS STD Control and Prevention, Beijing, China
    J Acquir Immune Defic Syndr 53:S54-60. 2010
    ..To assess HIV/sexually transmitted infection (STI) prevalence and associated risk factors among miners in Yunnan, China...
  97. ncbi Using performance indicators to evaluate an environmental education program in artisanal gold mining communities in the Brazilian Amazon
    Rodolfo N Sousa
    Global Mercury Project, Norman B Keevil Institute of Mining Engineering, University of British Columbia, Vancouver, Canada
    Ambio 38:40-6. 2009
    ..A group of educators provided support to miners, training 4200 people in 141 mining locations. The effectiveness of this training was evaluated based on 20 performance indicators...
  98. ncbi Aerial measurements on uranium ore mining, milling and processing areas in Germany
    I Winkelmann
    Federal Office for Radiation Protection, 10318 Berlin, Germany
    J Environ Radioact 53:301-11. 2001
    ..These values are commonly found in the environment. In general, there is reasonable agreement between the results measured with different detectors and measuring methods...
  99. ncbi Mercury contamination in freshwater, estuarine, and marine fishes in relation to small-scale gold mining in Suriname, South America
    J H Mol
    Center for Agriculture Research in Suriname (CELOS, University of Suriname, Paramaribo, Suriname
    Environ Res 86:183-97. 2001
    The extent of mercury contamination in Surinamese food fishes due to small-scale gold mining was investigated by determination of the total mercury concentration in 318 freshwater fishes, 109 estuarine fishes, and 110 fishes from the ..
  100. ncbi Analysis of fatalities and injuries involving mining equipment
    W A Groves
    The Pennsylvania State University, Department of Energy and Mineral Engineering, 110 Hosler Building, University Park, PA 16802 5000, USA
    J Safety Res 38:461-70. 2007
    Despite significant reductions, the number of injuries and fatalities in mining remains high. A persistent area of concern continues to be equipment-related incidents.
  101. pmc Lead sources, behaviors, and socioeconomic factors in relation to blood lead of native american and white children: a community-based assessment of a former mining area
    Lorraine Halinka Malcoe
    Masters in Public Health Program, Department of Family and Community Medicine, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Environ Health Perspect 110:221-31. 2002
    ..Further, the relation of mining waste to blood lead concentrations (BPbs) of rural children is controversial...

Research Grants95

  1. International Training & Research in Envir. and Occup. *
    Daniel Hryhorczuk; Fiscal Year: 2006
    ..Program Coordinator Program Administrator / RT in data management Research Training (RT) in , Komsomolsk and coal mining health programs Training in research bioethics BB rczuk, Daniel 0...
  2. Respiratory, reproductive, and other effects of air pollution and high altitude
    NELSON STEENLAND; Fiscal Year: 2007
    ..Water contamination by metals is an important problem in both Peru and Chile, where mining has increased and mine wastes have contaminated water and soils Ongoing Fogarty studies funded under our current ..
  3. International Training and Research in Environmental and Occupational Health
    NELSON K STEENLAND; Fiscal Year: 2012
    ..Water contamination by metals is an important problem in both Peru and Chile, where mining has increased and mine wastes have contaminated water and soils Ongoing Fogarty studies funded under our current ..
  4. International Training and Research in Environmental and Occupational Health
    NELSON K STEENLAND; Fiscal Year: 2010
    ..Water contamination by metals is an important problem in both Peru and Chile, where mining has increased and mine wastes have contaminated water and soils Ongoing Fogarty studies funded under our current ..
  5. International Training and Research in Environmental and Occupational Health
    NELSON STEENLAND; Fiscal Year: 2009
    ..Water contamination by metals is an important problem in both Peru and Chile, where mining has increased and mine wastes have contaminated water and soils Ongoing Fogarty studies funded under our current ..
  6. Comprehensive Clinical Decision Support for the Primary Care of Premature Infants
    Robert W Grundmeier; Fiscal Year: 2010
    ..The intervention will consist of (1) a real-time data mining tool functioning in the EHR that will organize large amounts of health information visually in a succinct time-..
  7. Ionic Liquid Gas Sensors for Detection of Flammable Gases In Workplace
    Xiangqun Zeng; Fiscal Year: 2010
    ..are essential in occupational health and safety to prevent fire or explosion in gas facilities and underground mining. Three things are needed to support a fire or explosion: a source of fuel (e.g...
  8. Ionic Liquid Gas Sensors for Detection of Flammable Gases In Workplace
    Xiangqun Zeng; Fiscal Year: 2009
    ..are essential in occupational health and safety to prevent fire or explosion in gas facilities and underground mining. Three things are needed to support a fire or explosion: a source of fuel (e.g...
  9. Catalytic Approach to Treatment of Cyanide Poisoning
    SIGRIDUR SUMAN; Fiscal Year: 2009
    ..It is used industrially in tasks such as fumigation, electroplating, and mining, and accidental exposure can be life-threatening...
  10. Catalytic Approach to Treatment of Cyanide Poisoning
    SIGRIDUR G SUMAN; Fiscal Year: 2010
    ..It is used industrially in tasks such as fumigation, electroplating, and mining, and accidental exposure can be life-threatening...
  11. International Program for Mining Health and Safety
    Jefferey Burgess; Fiscal Year: 2006
    ..DO NOT EXCEED THE SPACE PROVIDED. Objectives: To improve environmental and occupational health associated with mining operations andmineral processing in sub-Saharan Africa through training, research, prevention and intervention...
  12. Data Mining Assisted Discovery of Novel Organophosphorou
    Robert Turner; Fiscal Year: 2005
    ..Unfortunately, many if not most are not active organophosphate hydrolases. We have developed a data mining method for identifying active OPH's...
  13. Pain Assessment & Intervention Needs (PAIN)
    Fern Fitzhenry; Fiscal Year: 2010
    ..The primary aim of the study is to analyze pain management by both hypothesis tests &data mining. Current pain management practice is informed with standards disseminated by the American Pain Society reflecting ..
  14. Estrogenic activity of uranium in vitro and in vivo
    CHERYL DYER; Fiscal Year: 2007
    ..S. In the mid 1940's active uranium (U) mining began in the Four Corners region of the southwest U.S. where the Navajo Nation is located...
  15. Nanoassay for Realtime Molecular Probing ABC Transporter
    Xiaohong Xu; Fiscal Year: 2009
    ..to use high resolution cryo transmission-electron-microscopy (cryo-TEM), computer reconstruction and structure mining to solve the structure and molecular mechanism(s) of BmrA, a multidrug bacterial transporter belonging to the ABC ..
  16. Mining the Structural Genomics Initiative for Disorder
    A Dunker; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  17. Sources and Wetting Characteristics of Respirable Coal and Silica Dust from Selec
    YOGINDER P CHUGH; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Increased productivity and high out-of-seam dilution (15% to 20%) mining in US underground coal mines continue to generate dust control problems and the need to develop and implement alternate more ..
  18. Mining the Structural Genomics Initiative for Disorder
    A Dunker; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  19. Sources and Wetting Characteristics of Respirable Coal and Silica Dust from Selec
    YOGINDER CHUGH; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Increased productivity and high out-of-seam dilution (15% to 20%) mining in US underground coal mines continue to generate dust control problems and the need to develop and implement alternate more ..
  20. A Systems Biology Approach to the Model Apicomplexan Toxoplasma gondii
    William J Sullivan Jr; Fiscal Year: 2010
    ..genomics and other high throughput technologies (thematic area 1) with a systems-level integration, analysis and mining of large datasets with the overarching goal of translating our discoveries into new insights into therapy and ..
  21. Characterization and testing of novel genes in DNA double-strand break repair
    Claudia Wiese; Fiscal Year: 2010
    ..a global meta-analysis (GMA) of over 3,600 human 2-color microarray datasets in combination with literature data-mining software...
  22. Research Training on Chronic Lung Diseases in Southern Africa
    Thomas Robins; Fiscal Year: 2009
    ..g., silica associated with mining &construction industries, respirable dust in coal mines, allergens and endotoxin associated with agriculture ..
  23. Small Molecule Inhibitors of Anthrax Lethal Factor
    NORTON PEET; Fiscal Year: 2006
    ..molecule LF inhibitors through a combination of screening of chemical libraries and 3D sub-structure database mining. These inhibitors have been shown to specifically bind to LF with low (M potencies in enzymatic assays and to ..
  24. Small Molecule Inhibitors of Anthrax Lethal Factor
    NORTON PEET; Fiscal Year: 2005
    ..molecule LF inhibitors through a combination of screening of chemical libraries and 3D sub-structure database mining. These inhibitors have been shown to specifically bind to LF with low (M potencies in enzymatic assays and to ..
  25. Advanced Computational Framework for Decision Support in Critically Ill Children
    Randall Wetzel; Fiscal Year: 2009
    ..Using AI and automated computational methodology we will develop algorithms for data mining raw medical data from disparate clinical data sources...
  26. Advanced Computational Framework for Decision Support in Critically Ill Children
    Randall C Wetzel; Fiscal Year: 2010
    ..Using AI and automated computational methodology we will develop algorithms for data mining raw medical data from disparate clinical data sources...
  27. Core--Genomics and Bioinformatics
    Peter Sorger; Fiscal Year: 2005
    ..for microarray fabrication, microarray analysis, database storage, large-scale database management, data mining and data modeling...
  28. EFFECT OF LEAD ON THE DEVELOPMENT OF AUDITORY TEMPORAL PROCESSING
    DIANA LURIE; Fiscal Year: 2002
    ..In states like Montana, where mining has resulted in regionally high levels of lead in the environment, there are focal regions where lead levels in ..
  29. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2000
    ..effectiveness in mobilizing a Native American community to respond to heavy metal contamination from lead and zinc mining. Ottawa County Oklahoma, the site of the proposed research, was heavily mined for zinc and lead in the first half ..
  30. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2002
    ..effectiveness in mobilizing a Native American community to respond to heavy metal contamination from lead and zinc mining. Ottawa County Oklahoma, the site of the proposed research, was heavily mined for zinc and lead in the first half ..
  31. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2003
    ..effectiveness in mobilizing a Native American community to respond to heavy metal contamination from lead and zinc mining. Ottawa County Oklahoma, the site of the proposed research, was heavily mined for zinc and lead in the first half ..
  32. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2001
    ..effectiveness in mobilizing a Native American community to respond to heavy metal contamination from lead and zinc mining. Ottawa County Oklahoma, the site of the proposed research, was heavily mined for zinc and lead in the first half ..
  33. A SOCIAL NETWORK-BASED INTERVENTION TO REDUCE LEAD EXPOS
    Michelle Kegler; Fiscal Year: 2004
    ..effectiveness in mobilizing a Native American community to respond to heavy metal contamination from lead and zinc mining. Ottawa County Oklahoma, the site of the proposed research, was heavily mined for zinc and lead in the first half ..
  34. EXPLOSION HAZARDS RELATED TO COMBUSTIBLE DUSTS
    CHARLES KAUFFMAN; Fiscal Year: 1992
    ..Traditionally these explosions have been associated with the agricultural and mining industries, but they have also occurred in other industries where a combustible dust is handled or generated, as ..
  35. Arsenic Phytosensors
    MARK ELLESS; Fiscal Year: 2009
    ..is often required to detect and monitor arsenic over large areas affected by activities such as pesticide use, mining, smelting, and construction with pressure-treated wood...
  36. Arsenic Phytosensors
    Mark P Elless; Fiscal Year: 2010
    ..is often required to detect and monitor arsenic over large areas affected by activities such as pesticide use, mining, smelting, and construction with pressure-treated wood...
  37. Proteomics of Porphyromonas gingivalis interactions with Fusobacterium nucleatum
    Murray Hackett; Fiscal Year: 2010
    ..This will include global protein modification analysis using data mining techniques, and a chemical approach to global phosphorylation specifically...
  38. Proteomics of Porphyromonas gingivalis interactions with Fusobacterium nucleatum
    Murray Hackett; Fiscal Year: 2012
    ..This will include global protein modification analysis using data mining techniques, and a chemical approach to global phosphorylation specifically...
  39. Algorithms and Image Analysis Software Tool for Automated Recognition and Identif
    JELENA KOVACEVIC; Fiscal Year: 2009
    ..While this trove hides answers to a host of important questions, mining it visually, as it is typically done, is an enormous and error-prone task wasting valuable resources...
  40. Chaperone Mining of the Chlamydia Type Three Secretion System
    Ellena Peterson; Fiscal Year: 2009
    ..Having an understanding of the critical elements of the Chlamydia TTS system should lead to the development of strategies to subvert the TTS system with the ultimate goal of attenuating or preventing infections with this pathogen. ..
  41. Chaperone Mining of the Chlamydia Type Three Secretion System
    Ellena Peterson; Fiscal Year: 2007
    ..Having an understanding of the critical elements of the Chlamydia TTS system should lead to the development of strategies to subvert the TTS system with the ultimate goal of attenuating or preventing infections with this pathogen. ..
  42. In Silico Model for Acute Lung Injury Prediction and Clinical Trial Design
    Ognjen Gajic; Fiscal Year: 2010
    ..b) a rule based model to capture clinicians'putative knowledge and expertise, and c) a probabilistic/data mining model derived from empirical evidence extracted from electronic medical records and clinical trial databases...
  43. Algorithms and Image Analysis Software Tool for Automated Recognition and Identif
    JELENA KOVACEVIC; Fiscal Year: 2010
    ..While this trove hides answers to a host of important questions, mining it visually, as it is typically done, is an enormous and error-prone task wasting valuable resources...
  44. Chaperone Mining of the Chlamydia Type Three Secretion System
    ELLENA MARIE PETERSON; Fiscal Year: 2010
    ..Having an understanding of the critical elements of the Chlamydia TTS system should lead to the development of strategies to subvert the TTS system with the ultimate goal of attenuating or preventing infections with this pathogen. ..
  45. Chaperone Mining of the Chlamydia Type Three Secretion System
    Ellena Peterson; Fiscal Year: 2006
    ..Having an understanding of the critical elements of the Chlamydia TTS system should lead to the development of strategies to subvert the TTS system with the ultimate goal of attenuating or preventing infections with this pathogen. ..
  46. Enhancing the Biomedical Computing Platform for Pancreatic Cancer Research
    Simon Sherman; Fiscal Year: 2010
    ..with other related systems;(ii) compliant with the emerging requirements for data collection, access, mining, management and sharing;and (iii) a computing platform useful for developing novel hypotheses and studies aimed at ..
  47. Ontology-based Information Network to Support Vaccine Research
    Yongqun He; Fiscal Year: 2009
    ..Our goal is to develop the community-based Vaccine Ontology (VO) and apply it to efficient vaccine literature mining and analysis of protective immune mechanisms...
  48. Mining the Multiple Sclerosis miRNome for Disease Markers
    Amy Lovett Racke; Fiscal Year: 2009
    ..This study is designed to identify normally occurring microRNA that may be dysregulating, promoting autoimmunity. The data will enable us to identify new therapeutic targets and disease biomarkers for MS. ..
  49. Mining the Multiple Sclerosis miRNome for Disease Markers
    Amy E Lovett Racke; Fiscal Year: 2010
    ..This study is designed to identify normally occurring microRNA that may be dysregulating, promoting autoimmunity. The data will enable us to identify new therapeutic targets and disease biomarkers for MS. ..
  50. Mining Soil Metagenome for Novel Biodegradation Genes
    Ronald Crawford; Fiscal Year: 2003
    ..abstract_text> ..
  51. Mining the Soil Metagenome for Novel Biodegradation Gen*
    Ronald Crawford; Fiscal Year: 2004
    ..abstract_text> ..
  52. Mining the Structural Genomics Initiative for Disorder
    A Dunker; Fiscal Year: 2009
    ..Alsoof importance is that this workwill significantly increase the sequence-function informationobtained from the structural genomics initiative with very little incremental increase over the current investment. ..
  53. Natural Language Processing for Cancer Research Network Surveillance Studies
    David Carrell; Fiscal Year: 2009
    ..HMO Cancer Research Network (CRN) of "industrial-strength" natural language processing (NLP) systems useful for mining valuable, research-grade information from unstructured clinical text...
  54. Natural Language Processing for Cancer Research Network Surveillance Studies
    David Carrell; Fiscal Year: 2010
    ..HMO Cancer Research Network (CRN) of "industrial-strength" natural language processing (NLP) systems useful for mining valuable, research-grade information from unstructured clinical text...
  55. CHEMICAL ENVIRONMENTAL PROBLEMS ASSOCIATED WITH MINING
    RUTH BILLINGS; Fiscal Year: 1992
    This program will focus on the most common chemical contaminants which results, or have resulted from mining of gold and silver in the desert environment of the Western United States. The program consists of six projects...
  56. CORE--Community Outreach and Translation Core
    Howard Hu; Fiscal Year: 2004
    ..studies pertaining to the health risks to children that are associated with exposures to metals in mining waste; the potential interactions between metals in mining waste and nutritional status; and personal and culture-..
  57. MURINE TYPHUS: VECTOR BIOLOGY AND TRANSMISSION
    Abdu Azad; Fiscal Year: 2009
    ..Thus, we will use an integrated approach including the combination of rickettsial genome data mining, pathogen phylogenomic analysis and empirical studies to investigate the patterns of rickettsial and host ..
  58. Root exudates as a new chemical-mining pool for isolation of novel antimicrobials
    HARSH BAIS; Fiscal Year: 2009
    ..It is expected that these novel efforts will lead to the development of new therapeutics for treatment of E. faecalis and E. faecium infections either by a stand-alone drug or by augmenting the effectiveness of existing drug therapies. ..
  59. Phytostablization of Mine Tailings
    Raina Maier; Fiscal Year: 2005
    Extensive mining activity in arid and semi-arid ecosystems of the southwestern United States has resulted in large numbers of tailings sites with elevated metal concentrations ranging between 0.1 and 5% (w/w)...
  60. Root exudates as a new chemical-mining pool for isolation of novel antimicrobials
    Harsh P Bais; Fiscal Year: 2010
    ..It is expected that these novel efforts will lead to the development of new therapeutics for treatment of E. faecalis and E. faecium infections either by a stand-alone drug or by augmenting the effectiveness of existing drug therapies. ..
  61. Active Hearing Protectors and Audibility of Critical Communications
    Anthony Brammer; Fiscal Year: 2006
    ..worn by aircraft air and ground crews, military personnel, and emergency responders, and persons in industry, mining and construction working in noisy environments, have long complained that HPDs interfere with their ability to ..
  62. Active Hearing Protectors and Audibility of Critical Communications
    Anthony Brammer; Fiscal Year: 2009
    ..worn by aircraft air and ground crews, military personnel, and emergency responders, and persons in industry, mining and construction working in noisy environments, have long complained that HPDs interfere with their ability to ..
  63. DESIGN OF NOVEL D1 DOPAMINE RECEPTOR LIGANDS
    Alexander Tropsha; Fiscal Year: 2000
    ..of novel methods of data analysis (Quantitative Structure-Activity Relationships, QSAR) and prediction (database mining, de novo design)...
  64. Active Hearing Protectors and Audibility of Critical Communications
    Anthony Brammer; Fiscal Year: 2007
    ..worn by aircraft air and ground crews, military personnel, and emergency responders, and persons in industry, mining and construction working in noisy environments, have long complained that HPDs interfere with their ability to ..
  65. SPATIALLY ORIENTED DATABASE FOR DIGITAL BRAIN IMAGES
    Edward H Herskovits; Fiscal Year: 2010
    ..First, our current data-mining approaches are designed to generate Bayesian networks that model a structure-function relationship;that is, these ..
  66. SPATIALLY ORIENTED DATABASE FOR DIGITAL BRAIN IMAGES
    Edward Herskovits; Fiscal Year: 2009
    ..First, our current data-mining approaches are designed to generate Bayesian networks that model a structure-function relationship;that is, these ..
  67. Data Mining Based Noninvasive Intracranial Pressure Assessment
    Xiao Hu; Fiscal Year: 2007
    ..unreadable] [unreadable] The objectives of this project are to develop and validate a data mining based, noninvasive ICP assessment method...
  68. Droplet Compartmentalized Selection for Deep-Mining of Antibody Diversity
    JOHN HEYMAN; Fiscal Year: 2009
    ..Moreover, because the antibodies from a single cell can be detected, it becomes possible to directly screen non-immortalized cells instead of hybridomas, further increasing the antibody diversity that can be accessed. ..
  69. Using Electronic Data to Improve Care of Patients with Known or Suspected Cancer
    Hardeep Singh; Fiscal Year: 2010
    ..We will build upon our previous and ongoing work in innovative data mining techniques to identify patients likely to have delays in cancer diagnosis or treatment, and we will facilitate ..
  70. Mining the Aspergillus nidulans Secondary Metabolome
    Berl Oakley; Fiscal Year: 2009
    This is an application for a competitive revision of Program Project grant (5P01GM084077) entitled "Mining the Aspergillus nidulans Secondary Metabolome," It is written in response to Notice Number NOT-OD-09-058, Notice Title: NIH ..
  71. Using Electronic Data to Improve Care of Patients with Known or Suspected Cancer
    Hardeep Singh; Fiscal Year: 2009
    ..We will build upon our previous and ongoing work in innovative data mining techniques to identify patients likely to have delays in cancer diagnosis or treatment, and we will facilitate ..
  72. Pattern array: in vivo mining for novel psychoactive drug discovery
    GREGORY ELMER; Fiscal Year: 2009
    ..Data mining techniques are increasingly used to discover predictive in vitro system profiles for a cancer or toxicological ..
  73. Oogenesis, Spematogenesis and Sperm -Egg Interactions
    Martin Matzuk; Fiscal Year: 2004
    ..identification strategies including degenerate PCR, in silico subtraction, PCR-based subtraction, genome database mining, and GeneChip technology to characterize over 20 novel gonad-expressed genes...
  74. METAL MIXTURES AND CHILDREN'S HEALTH
    Howard Hu; Fiscal Year: 2004
    ..Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese, and others) in mining waste and populated by many residents of Native American descent...
  75. Multi-Hazard Sensor for Miners
    MICHAEL FRISH; Fiscal Year: 2006
    ..The mining industry presents particularly challenging safety and health needs...
  76. METAL MIXTURES AND CHILDREN'S HEALTH
    Joseph Brain; Fiscal Year: 2007
    ..Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese, and others) in mining waste and populated by many residents of Native American descent...
  77. TGFB AND GENE THERAPY IN SILICA INDUCED LUNG FIBROSIS
    Patricia Sime; Fiscal Year: 2001
    Inhalation of silica in mining, sandblasting and quarrying occupations results in serious, potentially life threatening, pulmonary inflammatory and fibrotic pathologies including acute and chronic (nodular pulmonary fibrosis) silicosis...
  78. METAL MIXTURES AND CHILDREN'S HEALTH
    Howard Hu; Fiscal Year: 2006
    ..Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese, and others) in mining waste and populated by many residents of Native American descent...
  79. METAL MIXTURES AND CHILDREN'S HEALTH
    Howard Hu; Fiscal Year: 2005
    ..Superfund site of Oklahoma - an area highly contaminated by metals (lead, cadmium, iron, manganese, and others) in mining waste and populated by many residents of Native American descent...
  80. TGFB AND GENE THERAPY IN SILICA INDUCED LUNG FIBROSIS
    Patricia Sime; Fiscal Year: 2002
    Inhalation of silica in mining, sandblasting and quarrying occupations results in serious, potentially life threatening, pulmonary inflammatory and fibrotic pathologies including acute and chronic (nodular pulmonary fibrosis) silicosis...
  81. TGFB AND GENE THERAPY IN SILICA INDUCED LUNG FIBROSIS
    Patricia Sime; Fiscal Year: 2003
    Inhalation of silica in mining, sandblasting and quarrying occupations results in serious, potentially life threatening, pulmonary inflammatory and fibrotic pathologies including acute and chronic (nodular pulmonary fibrosis) silicosis...
  82. TGFB AND GENE THERAPY IN SILICA INDUCED LUNG FIBROSIS
    Patricia Sime; Fiscal Year: 2005
    Inhalation of silica in mining, sandblasting and quarrying occupations results in serious, potentially life threatening, pulmonary inflammatory and fibrotic pathologies including acute and chronic (nodular pulmonary fibrosis) silicosis...
  83. TGFB AND GENE THERAPY IN SILICA INDUCED LUNG FIBROSIS
    Patricia Sime; Fiscal Year: 2004
    Inhalation of silica in mining, sandblasting and quarrying occupations results in serious, potentially life threatening, pulmonary inflammatory and fibrotic pathologies including acute and chronic (nodular pulmonary fibrosis) silicosis...
  84. TOXIC SUBSTANCES IN THE ENVIRONMENT
    Martyn Smith; Fiscal Year: 1999
    ..To better understand the release and transport of toxic metals and other contaminants from inactive mining sites and from various combustion processes; 5...
  85. Phase II: Advanced Personal Gas Detectors for Mining Applications
    DMITRI ROUTKEVITCH; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: The mining industry is one of the more challenging occupational sectors that involve adverse workers conditions, including ..
  86. Phase II: Advanced Personal Gas Detectors for Mining Applications
    DMITRI ROUTKEVITCH; Fiscal Year: 2009
    ..PUBLIC HEALTH RELEVANCE: The mining industry is one of the more challenging occupational sectors that involve adverse workers conditions, including ..
  87. Graduate Industrial Hygiene Training Program Grant, University of Arizona
    Jefferey Burgess; Fiscal Year: 2009
    ..Given the national and global need for Industrial Hygienists with experience in mining and our extensive partnership with the Department of Mining and Geological Engineering at the University of ..
  88. Urinary Continence Index for Prediction of Urinary Incontinence in Older Women
    Mohammad Reza Siadat; Fiscal Year: 2011
    ..Developing reliable and effective statistical models to aid in mining data enhances the ability to utilize the data to answer novel research questions with significant potential to ..
  89. A Prospective Birth Cohort Study Involving Uranium Exposure in the Navajo Nation
    Johnnye L Lewis; Fiscal Year: 2010
    ..the prenatal, perinatal, and early postnatal health effects of environmental exposures to uranium and associated mining wastes on Navajo mothers and their offspring through the following specific aims: Aim 1: Co-operatively design and ..
  90. POSTURAL STABILITY EFFECTS IN LOW SEAM MINING TASKS
    Amit Bhattacharya; Fiscal Year: 1999
    ..These findings will provide the framework within which future mining worker- population-based prospective studies can be designed to address the following issues...
  91. POSTURAL STABILITY EFFECTS IN LOW SEAM MINING TASKS
    Amit Bhattacharya; Fiscal Year: 2000
    ..These findings will provide the framework within which future mining worker- population-based prospective studies can be designed to address the following issues...
  92. POSTURAL STABILITY EFFECTS IN LOW SEAM MINING TASKS
    Amit Bhattacharya; Fiscal Year: 2001
    ..These findings will provide the framework within which future mining worker- population-based prospective studies can be designed to address the following issues...