nuclear warfare

Summary

Summary: Warfare involving the use of nuclear weapons.

Top Publications

  1. ncbi Radiation exposure due to local fallout from Soviet atmospheric nuclear weapons testing in Kazakhstan: solid cancer mortality in the Semipalatinsk historical cohort, 1960-1999
    Susanne Bauer
    Federal Office for Radiation Protection, Institute for Radiation Hygiene, Germany
    Radiat Res 164:409-19. 2005
  2. ncbi Solid cancer incidence in atomic bomb survivors: 1958-1998
    D L Preston
    Hirosoft International, Eureka, California, USA
    Radiat Res 168:1-64. 2007
  3. ncbi Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 160:381-407. 2003
  4. ncbi Noncancer disease incidence in atomic bomb survivors, 1958-1998
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 161:622-32. 2004
  5. ncbi Radiation effects on breast cancer risk: a pooled analysis of eight cohorts
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 158:220-35. 2002
  6. ncbi Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 162:377-89. 2004
  7. ncbi Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors
    T Hayashi
    Department of Radiobiology, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ward, Hiroshima 732 0815 Japan
    Int J Radiat Biol 79:129-36. 2003
  8. ncbi Effects of radiation on fatty liver and metabolic coronary risk factors among atomic bomb survivors in Nagasaki
    Masazumi Akahoshi
    Department of Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan
    Hypertens Res 26:965-70. 2003
  9. ncbi Prevalence of atherosclerosis in relation to atomic bomb radiation exposure: an RERF Adult Health Study
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Int J Radiat Biol 81:821-6. 2005
  10. ncbi Dose estimation for atomic bomb survivor studies: its evolution and present status
    Harry M Cullings
    Departments of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 166:219-54. 2006

Research Grants

  1. Protectan CBLB502
    Andrei Gudkov; Fiscal Year: 2009
  2. HIGH ENERGY IONS AND GENOMIC INSTABILITY
    Eric Hall; Fiscal Year: 2001
  3. KIDNEY RESPONSE TO RADIATION AND CHEMOTHERAPY
    JOHN MOULDER; Fiscal Year: 2006
  4. Near infrared/MR system for imaging brain oxygenation
    Harold Swartz; Fiscal Year: 2004
  5. Determination of Clinical Feasibility of EPR Oximetry of Tumors
    Harold Swartz; Fiscal Year: 2007
  6. BioDose-08 Conference
    Harold Swartz; Fiscal Year: 2008
  7. Measurement of pO2 in tissues in vivo and in vitro
    Harold Swartz; Fiscal Year: 2006
  8. Development of a Diagnostic Test for Alzheimer's Disease
    Mark Lovell; Fiscal Year: 2007
  9. Neuronogenesis in the Non-pigmented Retina
    RICHARD NOWAKOWSKI; Fiscal Year: 2008
  10. Cardiovascular Risk 50 Years After Thymic Irradiation
    Michael Adams; Fiscal Year: 2007

Detail Information

Publications189 found, 100 shown here

  1. ncbi Radiation exposure due to local fallout from Soviet atmospheric nuclear weapons testing in Kazakhstan: solid cancer mortality in the Semipalatinsk historical cohort, 1960-1999
    Susanne Bauer
    Federal Office for Radiation Protection, Institute for Radiation Hygiene, Germany
    Radiat Res 164:409-19. 2005
    ..Future epidemiological assessments based on this cohort will benefit from extension of follow-up and ongoing validation of dosimetric data...
  2. ncbi Solid cancer incidence in atomic bomb survivors: 1958-1998
    D L Preston
    Hirosoft International, Eureka, California, USA
    Radiat Res 168:1-64. 2007
    ..In view of the persisting increase in solid cancer risks, the LSS should continue to provide important new information on radiation exposure and solid cancer risks for at least another 15 to 20 years...
  3. ncbi Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 160:381-407. 2003
    ..Lifetime risk summaries are used to examine uncertainties of the LSS noncancer disease findings...
  4. ncbi Noncancer disease incidence in atomic bomb survivors, 1958-1998
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 161:622-32. 2004
    ..These results attest to the need for continued follow-up of the aging A-bomb survivors to fully elucidate the effects of radiation exposure on the occurrence of noncancer diseases...
  5. ncbi Radiation effects on breast cancer risk: a pooled analysis of eight cohorts
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 158:220-35. 2002
    ..There is also a suggestion that women with some benign breast conditions may be at elevated risk of radiation-associated breast cancer...
  6. ncbi Effect of recent changes in atomic bomb survivor dosimetry on cancer mortality risk estimates
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 162:377-89. 2004
    ..Whether or not one makes allowance for this, there is no statistically significant city difference in the estimated cancer risk...
  7. ncbi Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors
    T Hayashi
    Department of Radiobiology, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ward, Hiroshima 732 0815 Japan
    Int J Radiat Biol 79:129-36. 2003
    ....
  8. ncbi Effects of radiation on fatty liver and metabolic coronary risk factors among atomic bomb survivors in Nagasaki
    Masazumi Akahoshi
    Department of Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan
    Hypertens Res 26:965-70. 2003
    ..It is suggested that these associations are involved in the basic mechanism(s) linking radiation exposure and CHD...
  9. ncbi Prevalence of atherosclerosis in relation to atomic bomb radiation exposure: an RERF Adult Health Study
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Int J Radiat Biol 81:821-6. 2005
    ..To determine whether exposure to atomic bomb radiation altered the prevalence of asymptomatic atherosclerosis...
  10. ncbi Dose estimation for atomic bomb survivor studies: its evolution and present status
    Harry M Cullings
    Departments of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 166:219-54. 2006
    ..We summarize calculated doses and illustrate their change and elaboration through the various systems for a hypothetical example case in each city. We conclude with a description of current efforts and plans for further improvements...
  11. ncbi Review of methods of dose estimation for epidemiological studies of the radiological impact of nevada test site and global fallout
    Harold L Beck
    Radiat Res 166:209-18. 2006
    ..This paper summarizes the various methods of dose estimation from weapons test fallout and the most important dose assessment and epidemiology studies that have relied on those methods...
  12. ncbi A perspective on public concerns about exposure to fallout from the production and testing of nuclear weapons
    F Owen Hoffman
    SENES Oak Ridge, Inc, TN 37830, USA
    Health Phys 82:736-48. 2002
    ....
  13. ncbi Long-lasting alterations of the immune system by ionizing radiation exposure: implications for disease development among atomic bomb survivors
    Yoichiro Kusunoki
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, 5 2, Hijiyama Park, Minami Ward, Hiroshima 732, Japan
    Int J Radiat Biol 84:1-14. 2008
    ....
  14. ncbi Age-time patterns of cancer to be anticipated from exposure to general mutagens
    Donald A Pierce
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima 732 0815, Japan
    Biostatistics 4:231-48. 2003
    ..It is indicated that the model consequences conform remarkably well to observations from cohort studies of the A-bomb survivors, miners with prolonged exposure to radon, and cigarette smokers who stopped smoking at various ages...
  15. ncbi Dose response and temporal patterns of radiation-associated solid cancer risks
    D L Preston
    Department of Statistics, Radiation Effects Research Foundation, 5 2 Hijiyama Koen, Minami Ku, Hiroshima, 732 0815 Japan
    Health Phys 85:43-6. 2003
    ....
  16. ncbi Thyroid disease associated with exposure to the Nevada nuclear weapons test site radiation: a reevaluation based on corrected dosimetry and examination data
    Joseph L Lyon
    Department of Family and Preventive Medicine, School of Medicine, University of Utah, Salt Lake City, UT 84108, USA
    Epidemiology 17:604-14. 2006
    ..In 1993, we reported that among those examined in 1985 to 1986 (Phase II) there was an association between radiation from the Nevada Test Site and thyroid neoplasms...
  17. pmc Low dose radiation and cancer in A-bomb survivors: latency and non-linear dose-response in the 1950-90 mortality cohort
    Greg Dropkin
    Flat 5, 32 Sheil Rd, Liverpool L6 3AE, UK
    Environ Health 6:1. 2007
    ..Do radiation doses below 20 mSv have significant impact on cancer mortality in Japanese A-bomb survivors, and is the dose-response linear?..
  18. ncbi Effects of radiation on the longitudinal trends of hemoglobin levels in the Japanese atomic bomb survivors
    F Lennie Wong
    Departments of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 164:820-7. 2005
    ..Sex and birth cohort differences in radiation effects were not found after adjusting for smoking. The radiation-induced reduction in hemoglobin levels could not be explained by the presence of certain anemia-associated diseases...
  19. ncbi Understanding estimation of time and age effect-modification of radiation-induced cancer risks among atomic-bomb survivors
    Frederic Lagarde
    Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima 732 0815, Japan
    Health Phys 91:608-18. 2006
    ..Also, due to collinearity between these effect-modifier variables, all three models with two of the effect-modifiers necessarily show equivalent fits...
  20. ncbi Radiation-induced leukemia: lessons from history
    Stuart C Finch
    University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, USA
    Best Pract Res Clin Haematol 20:109-18. 2007
    ..The discussion in this section also covers some concepts of radiation-induced cell damage and ruminations on unanswered questions...
  21. ncbi Nuclear weapons tests and human germline mutation rate
    Yuri E Dubrova
    Department of Genetics, University of Leicester, Leicester LE1 7RH, UK
    Science 295:1037. 2002
  22. ncbi Hepatocellular carcinoma among atomic bomb survivors: significant interaction of radiation with hepatitis C virus infections
    Gerald B Sharp
    Department of Epidemiology, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima, 732 0815 Japan
    Int J Cancer 103:531-7. 2003
    ....
  23. ncbi Radiation-related mortality among offspring of atomic bomb survivors: a half-century of follow-up
    Shizue Izumi
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Int J Cancer 107:292-7. 2003
    ..However, because of uncertainty due to the small number of deaths and relatively young ages of subjects, we cannot rule out an increase in disease mortality at this time...
  24. pmc Non-cancer diseases of Korean atomic bomb survivors in residence at Hapcheon, Republic of Korea
    Young Su Ju
    Department of Occupational and Environmental Medicine, Sacred Heart Hospital, Hallym University, Anyang, Korea
    J Korean Med Sci 21:385-90. 2006
    ..24; 1.06-1.44), chronic liver disease (2.07; 1.51-2.84), and hypercholesterolemia (1.79; 1.11-2.90) than controls. This study suggests that A-bomb exposure is associated with a higher prevalence of non-cancer diseases in Korean survivors...
  25. ncbi Joint effects of radiation and smoking on lung cancer risk among atomic bomb survivors
    Donald A Pierce
    Department of Statistics, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Hiroshima 732, Japan
    Radiat Res 159:511-20. 2003
    ..The adjustment also removes an artifactual age-at-exposure effect in the radiation relative risk, opposite in direction to other cancers, which is due to birth cohort variation in lung cancer rates...
  26. ncbi Selection bias in cancer risk estimation from A-bomb survivors
    Donald A Pierce
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 167:735-41. 2007
    ..05 to 0.07. For solid cancer this would correspond to bias in the excess relative risk at 1 Sv of at most about 15-20%...
  27. ncbi Persistent subclinical inflammation among A-bomb survivors
    K Neriishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Hiroshima, Japan
    Int J Radiat Biol 77:475-82. 2001
    ..To investigate the associations between inflammation tests and radiation dose in A-bomb survivors...
  28. ncbi The effects of aging and radiation exposure on blood pressure levels of atomic bomb survivors
    Hideo Sasaki
    Department of Clinical Studies and Statistics, Radiation Effect Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima, Japan
    J Clin Epidemiol 55:974-81. 2002
    ..This phenomenon is compatible with the degenerative effect of ionizing radiation on blood vessels...
  29. ncbi Long-term effects of radiation dose on inflammatory markers in atomic bomb survivors
    Tomonori Hayashi
    Department of Radiobiology Molecular Epidemiology, Hiroshima University Faculty of Dentistry, Hiroshima, Japan
    Am J Med 118:83-6. 2005
  30. ncbi Impact of comparison group on cohort dose response regression: an example using risk estimation in atomic-bomb survivors
    J B Cologne
    Department of Statistics, Hiroshima, Japan
    Health Phys 80:491-6. 2001
    ..Consideration of heterogeneity in comparison groups is particularly important in dose-response studies focused on low doses at which the response may be comparable in magnitude to such heterogeneity...
  31. ncbi Psychiatric sequelae in atomic bomb survivors in Hiroshima and Nagasaki two decades after the explosions
    Michiko Yamada
    Department of Clinical Studies, Radiation Effects Research Foundation, 5 2 Hijiyama Park, Minami Ku, Hiroshima, 732 0815 Japan
    Soc Psychiatry Psychiatr Epidemiol 37:409-15. 2002
    ..The psychiatric effects of exposure to the atomic bomb explosions in Hiroshima and Nagasaki were assessed in this study...
  32. ncbi Risks of non-cancer disease incidence and mortality in the Japanese atomic bomb survivors
    Mark P Little
    J Radiol Prot 24:327-8. 2004
  33. ncbi Biological dosimetry of atomic bomb survivors exposed within 500 meters from the hypocenter and the health consequences
    N Kamada
    Department of Cancer Cytogenetics, Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan
    J Radiat Res 40:155-64. 1999
    ..Further continuous follow-up study of these heavily exposed people will give us more information on the late effects of A-bomb radiation, which may arise in the future...
  34. ncbi Chernobyl and the future: too soon for a final diagnosis
    Dillwyn Williams
    Thyroid Carcinogenesis Research Group, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
    Nature 440:993-4. 2006
  35. ncbi External dose estimates for Dolon village: application of the U.S./Russian joint methodology
    Steven L Simon
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA
    J Radiat Res 47:A143-7. 2006
    ..This report presents the basic elements of the joint methodology model for estimation of external dose received from SNTS fallout...
  36. ncbi Cataract in atomic bomb survivors
    A Minamoto
    Department of Ophthalmology, Hiroshima University School of Medicine, Hiroshima, Japan
    Int J Radiat Biol 80:339-45. 2004
    ..Ophthalmologic examinations were conducted on atomic bomb (A-bomb) survivors 55 years after exposure...
  37. ncbi Histologic characteristics of skin cancer in Hiroshima and Nagasaki: background incidence and radiation effects
    Masao Kishikawa
    Nagasaki Institute for Diagnostic Pathology, Isahaya, Japan
    Int J Cancer 117:363-9. 2005
    ....
  38. ncbi Male breast cancer incidence among atomic bomb survivors
    Elaine Ron
    Radiation Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, 6120 Executive Blvd, MSC 7362, Bethesda, MD 20892 7362, USA
    J Natl Cancer Inst 97:603-5. 2005
    ....
  39. ncbi Flexible dose-response models for Japanese atomic bomb survivor data: Bayesian estimation and prediction of cancer risk
    James Bennett
    Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    Radiat Environ Biophys 43:233-45. 2004
    ..Overall, cancer incidence risks predicted by Bayesian Markov Chain Monte Carlo methods are similar to those derived by classical likelihood-based methods and which form the basis of established estimates of radiation-induced cancer risk...
  40. ncbi Joint effects of radiation and smoking on lung cancer risk among Atomic bomb survivors
    D A Pierce
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima 732, Japan
    Radiat Res 163:694-5. 2005
  41. ncbi Incidence of multiple primary cancers in Nagasaki atomic bomb survivors: association with radiation exposure
    Masahiro Nakashima
    Tissue and Histopathology Section, Division of Scientific Data Registry, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Medicine, Nagasaki 851 8523, Japan
    Cancer Sci 99:87-92. 2008
    ..These results on the incidence of MPC in the tumor-bearing survivors and its correlations with the atomic bombing of 62 years ago are described for the first time in this report...
  42. ncbi DS02 fluence spectra for neutrons and gamma rays at Hiroshima and Nagasaki with fluence-to-kerma coefficients and transmission factors for sample measurements
    Stephen D Egbert
    Science Applications International Corporation, 10260 Campus Point Drive, San Diego, CA 92121, USA
    Radiat Environ Biophys 46:311-25. 2007
    ....
  43. ncbi Radiation dose estimation by tooth enamel EPR dosimetry for residents of Dolon and Bodene
    Kassym Zhumadilov
    Research Institute for Radiation Biology and Medicine, Hiroshima University, Japan
    J Radiat Res 47:A47-53. 2006
    ..1+/-45.5 mGy before 1949 while the younger population received up to about 100 mGy with an average value of 11.5+/-37.7 mGy...
  44. ncbi Progress in assessing the public health impact from residues of nuclear bomb testing in Kazakhstan
    Bernd Grosche
    J Radiol Prot 25:123-4. 2005
  45. ncbi Tritium in well waters, streams and atomic lakes in the East Kazakhstan Oblast of the Semipalatinsk Nuclear Test Site
    Peter I Mitchell
    Department of Experimental Physics, University College Dublin, Belfield, Dublin 4, Ireland
    J Radiol Prot 25:141-8. 2005
    ..Annual doses to humans arising from the ingestion of tritium in these well waters are very low at the present time and are of no radiological significance...
  46. ncbi The presence of BRAF point mutation in adult papillary thyroid carcinomas from atomic bomb survivors correlates with radiation dose
    Keiko Takahashi
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan
    Mol Carcinog 46:242-8. 2007
    ..039 and P=0.010, respectively). These results suggest that involvement of BRAF mutation in thyroid carcinogenesis in exposed people may differ from that in the nonexposed people...
  47. ncbi External radiation in Dolon village due to local fallout from the first USSR atomic bomb test in 1949
    Tetsuji Imanaka
    Research Reactor Institute, Kyoto University, Osaka, Japan
    J Radiat Res 47:A121-7. 2006
    ..Finally, 0.50 Gy of absorbed dose in air was derived as our tentative estimate for 1-year cumulative external dose in Dolon due to local fallout from the first USSR test in 1949...
  48. ncbi Retrospective dose assessment for the population living in areas of local fallout from the Semipalatinsk Nuclear Test Site Part II: Internal exposure to thyroid
    Konstantin Gordeev
    J Radiat Res 47:A137-41. 2006
    ..2006) in this conference, are presented. The main sources of uncertainty in the estimates are identified...
  49. ncbi Radiation exposure and thyroid cancer
    F Owen Hoffman
    JAMA 296:513; author reply 514. 2006
  50. ncbi Results of EPR dosimetry for population in the vicinity of the most contaminating radioactive fallout trace after the first nuclear test in the Semipalatinsk test site
    Alexander Ivannikov
    Research Institute for Radiation Biology and Medicine RIRBM, Hiroshima University, Japan
    J Radiat Res 47:A39-46. 2006
    ..25 Gy. These results are in agreement with the pattern of radioactive contamination of the territory after the nuclear test of 1949 except one case of extremely high dose, which should be additionally investigated...
  51. ncbi Considerations regarding the implementation of EPR dosimetry for the population in the vicinity of Semipalatinsk nuclear test site based on experience from other radiation accidents
    Valeriy Skvortsov
    Medical Radiological Research Center MRRC, Obninsk, Russia
    J Radiat Res 47:A61-9. 2006
    ....
  52. ncbi Plutonium and uranium in human bones from areas surrounding the Semipalatinsk nuclear test site
    Masayoshi Yamamoto
    Low Level Radioactivity Laboratory, K INET, Kanazawa University, Ishikawa, Japan
    J Radiat Res 47:A85-94. 2006
    ..2 mSv, respectively. The annual intake of total U (234,235,238U) and its effective dose for 60 years were estimated as 30 Bq for adult and 0.1 mSv, respectively, for chronic ingestion...
  53. ncbi An overview on GSF activities at the Semipalatinsk Test Site, Kazakhstan
    Natalia Semioshkina
    GSF Institut für Strahlenschutz, Neuherberg, Germany
    J Radiat Res 47:A95-100. 2006
    ..Internal doses, based on food monitoring and whole body measurements, were calculated for adults and were in the range of 13-500 microSv/y due to radiocaesium and radiostrontium...
  54. ncbi Molecular basis of basal cell carcinogenesis in the atomic-bomb survivor population: p53 and PTCH gene alterations
    Terumi Mizuno
    Department of Radiobiology Molecular Epidemiology Hiroshima 732 0815, Japan
    Carcinogenesis 27:2286-94. 2006
    ..Moreover, 60% of high-IR tumors harbored both p53 and PTCH abnormalities compared with 23% of low-IR tumors. Therefore, alteration of both genes is likely to play a role in radiation-induced basal cell carcinogenesis...
  55. ncbi Radiological situation in the vicinity of Semipalatinsk nuclear test site: Dolon, Mostik, Cheremushka and Budene settlements
    Aya Sakaguchi
    Low Level Radioactivity Laboratory, K INET, Kanazawa University, Ishikawa, Japan
    J Radiat Res 47:A101-16. 2006
    ..The obtained data will be helpful for evaluating the current and future radiation risks to the people living around there...
  56. ncbi Around Semipalatinsk nuclear test site: progress of dose estimations relevant to the consequences of nuclear tests (a summary of 3rd Dosimetry Workshop on the Semipalatinsk nuclear test site area, RIRBM, Hiroshima University, Hiroshima, 9-11 of March, 200
    Valeriy F Stepanenko
    Research Institute for Radiation Biology and Medicine RIRBM, Hiroshima University, Japan
    J Radiat Res 47:A1-13. 2006
    ..The results of investigation of psychological consequences of nuclear tests, which are expressed in the form of verbal behaviour, were presented at this session as well...
  57. ncbi A dose-dependent decrease in the fraction of cases harboring M6P/IGF2R mutations in hepatocellular carcinomas from the atomic bomb survivors
    Keisuke S Iwamoto
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 166:870-6. 2006
    ....
  58. ncbi Unilateral multiple primary tumours in an atomic-bomb survivor
    M Morishita
    Department of Molecular Medicine, Atomic Bomb Disease Institute, Nagasaki University Graduate School of Biomedical Sciences, 1 12 4 Sakamoto, Nagasaki City Nagasaki 852 8523, Japan
    Clin Oncol (R Coll Radiol) 17:391-2. 2005
    ..This case study indicates that the risk of multiple primary tumours should be considered in older atomic-bomb survivors...
  59. ncbi Evaluation of 137Cs fallout from the Chernobyl accident in a forest soil and its impact on Alpine Lake sediments, Mercantour Massif, S.E. France
    S Rezzoug
    Laboratoire de Radiochimie, Sciences Analytiques et Environnement, University of Nice Sophia Antipolis, 28, avenue Valrose, 06108 Nice Cedex 02, France
    J Environ Radioact 85:369-79. 2006
    ..Thus the 137Cs external exposure impact was evaluated at 2 mSvy(-1) for 2002 in the most contaminated point...
  60. ncbi 60 years since atomic bombings of Hiroshima and Nagasaki: radiation effects research at RERF
    Burton G Bennett
    Radiat Res 164:235-6. 2005
  61. ncbi Width and center-axis location of the radioactive plume that passed over Dolon and nearby villages on the occasion of the first USSR A-bomb test in 1949
    Tetsuji Imanaka
    Research Reactor Institute, Kyoto University, Osaka, Japan
    J Radiat Res 46:395-9. 2005
    ..5 km. Additional soil contamination data around Dolon and other villages are necessary for more detailed discussion...
  62. ncbi Radiation dose-response relationships for thyroid nodules and autoimmune thyroid diseases in Hiroshima and Nagasaki atomic bomb survivors 55-58 years after radiation exposure
    Misa Imaizumi
    Department of Clinical Studies, Radiation Effects Research Foundation, Nagasaki, Japan
    JAMA 295:1011-22. 2006
    ..Effects of irradiation on thyroid diseases such as thyroid nodules and autoimmune thyroid diseases have not been evaluated among people exposed to radiation more than 50 years in the past...
  63. ncbi Thyroid disease 60 years after Hiroshima and 20 years after Chernobyl
    John D Boice
    JAMA 295:1060-2. 2006
  64. ncbi Ecological half-time and effective dose from chernobyl debris and from nuclear weapons fallout of 137Cs as measured in different Swedish populations
    C L Rääf
    Department of Radiation Physics, Lund University, Malmo University Hospital, SE 205 02 Malmo, Sweden
    Health Phys 90:446-58. 2006
    ....
  65. ncbi Radiation and noncancer diseases
    Colin R Muirhead
    Radiat Res 161:748. 2004
  66. ncbi Studies on the Hiroshima and Nagasaki survivors, and their use in estimating radiation risks
    C R Muirhead
    National Radiological Protection Board, Chilton, Didcot, Oxon OX11 0RQ, UK
    Radiat Prot Dosimetry 104:331-5. 2003
    ..Continued follow-up of the survivors will be important in shedding further light on these issues...
  67. ncbi The use of biologically based cancer risk models in radiation epidemiology
    D Krewski
    McLaughlin Centre for Population Health Risk Assessment, University of Ottawa, One Stewart Street, Room 320, Ottawa, Ontario, Canada K1N 6N5
    Radiat Prot Dosimetry 104:367-76. 2003
    ....
  68. ncbi Biological parameters for lung cancer in mathematical models of carcinogenesis
    P Jacob
    GSF Research Center for Environment and Health, Institute of Radiation Protection, D 85764 Neuherberg, Germany
    Radiat Prot Dosimetry 104:357-66. 2003
    ..Based on representative results for these three parameters, implications for the biological parameters in the TSCE model are derived...
  69. ncbi Evolution in zigzag--the changing state of A-bomb dosimetry
    A M Kellerer
    J Radiol Prot 22:337-9. 2002
  70. ncbi Monoclonal gammopathy of undetermined significance in atomic bomb survivors: incidence and transformation to multiple myeloma
    Kazuo Neriishi
    Department of Clinical Studies, Radiation Effects Research Foundation, Minami Ku, Hiroshima, Japan
    Br J Haematol 121:405-10. 2003
    ..6 per 100 000 person-years. The risk of MM mortality was greater in the older generation. The transformation from MGUS to MM was faster in exposed persons than in non-exposed persons, but this was not statistically significant...
  71. ncbi [Analysis of the epidemiological data concerning radiation carcinogenic effects and approaches to the low doses' upper limits determination in the aspect of a threshold of the unhealthy influences of ionizing radiation]
    L M Rozhdestvenskiĭ
    State Research Center Institute of Biophysics, Russian Ministry of Health, Moscow, 123182 Russia
    Radiats Biol Radioecol 43:227-36. 2003
    ..65 mGy. It can serve for evaluation of the dose rate threshold regarding the safe chronic radiation levels in the environment...
  72. ncbi Kazakhstan. For a long-suffering population, uncertainty reigns
    Richard Stone
    Science 300:1222. 2003
  73. ncbi Mortality of atomic bomb survivors predicted from laboratory animals
    Bruce A Carnes
    The Donald W Reynolds Department of Geriatric Medicine, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma 73190, USA
    Radiat Res 160:159-67. 2003
    ..These findings illustrate the value of comparative mortality analyses and the relevance of animal data to the study of human health effects...
  74. ncbi Cancer risk estimates for gamma-rays with regard to organ-specific doses Part II: site-specific solid cancers
    Linda Walsh
    Radiobiological Institute, University of Munich, Schillerstrasse 42, 80336 Munich, Germany
    Radiat Environ Biophys 43:225-31. 2004
    ..e. the organ that is closest to the body surface. However, this neutron contribution fraction is only about 10% for deeper lying organs, such as the colon...
  75. ncbi Absence of evidence for differences in the dose-response for cancer and non-cancer endpoints by acute injury status in the Japanese atomic-bomb survivors
    Mark P Little
    Department of Epidemiology and Public Health, Imperial College Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Int J Radiat Biol 78:1001-10. 2002
    ..To ascertain possible evidence for radiosensitive subgroups in the Japanese atomic-bomb survivors...
  76. ncbi Corrections in the atomic bomb data to examine low dose risk
    Gizelle S Baker
    Department of Biometry and Epidemiology at the Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA
    Health Phys 85:709-20. 2003
    ....
  77. ncbi New models for evaluation of radiation-induced lifetime cancer risk and its uncertainty employed in the UNSCEAR 2006 report
    M P Little
    Department of Epidemiology and Public Health, Imperial College, London, UK
    Radiat Res 169:660-76. 2008
    ..Linear-quadratic-exponential models predict lower risks (at least at low test doses) and appear to fit as well, although for other (theoretical) reasons we favor the simpler linear-quadratic models...
  78. ncbi Radiation risks and dirty bombs
    Joseph P Ring
    Harvard University Environmental Health and Safety Cambridge, MA 02138, USA
    Health Phys 86:S42-7. 2004
    ..This paper discusses the health risks from radiation exposure and compares them to risks from various activities of daily life and to exposure to hazardous chemicals...
  79. ncbi T cells of atomic bomb survivors respond poorly to stimulation by Staphylococcus aureus toxins in vitro: does this stem from their peripheral lymphocyte populations having a diminished naïve CD4 T-cell content?
    Yoichiro Kusunoki
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 158:715-24. 2002
    ..This may explain why A-bomb survivors tend to respond poorly to toxins encoded by the common pathogenic bacterium S. aureus...
  80. ncbi Comparisons of lung tumour mortality risk in the Japanese A-bomb survivors and in the Colorado Plateau uranium miners: support for the ICRP lung model
    M P Little
    Department of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, St Mary s Campus, Norfolk Place, London, W2 1PG, UK
    Int J Radiat Biol 78:145-63. 2002
    ..To estimate the ratio of risks for exposure to radon progeny relative to low-LET radiation based on human lung cancer data, taking account of possible time and age variations in radiation-induced lung cancer risk...
  81. pmc Ultrasound-detected thyroid nodule prevalence and radiation dose from fallout
    C E Land
    National Cancer Institute, Division of Cancer Epidemiology and Genetics, Bthesda, MD 20892 7238, USA
    Radiat Res 169:373-83. 2008
    ..In terms of excess relative risk per unit dose, our dose-response findings for nodule prevalence are comparable to those from populations exposed to medical X rays and to acute radiation from the Hiroshima and Nagasaki atomic bombings...
  82. ncbi Sixty years of follow-up of Hiroshima and Nagasaki survivors: current progress in molecular epidemiology studies
    Kei Nakachi
    Department of Radiobiology Molecular Epidemiology, Radiation Effects Research Foundation RERF, 5 2 Hijiyama Park, Minami Ku, Hiroshima shi, Hiroshima 732 0815, Japan
    Mutat Res 659:109-17. 2008
    ....
  83. ncbi The potential of amifostine: from cytoprotectant to therapeutic agent
    V Santini
    Dept of Hematology, Policlinico di Careggi, Viale Morgagni 85, 50134 Florence, Italy
    Haematologica 84:1035-42. 1999
    ..Amifostine was originally developed as a radioprotective agent in a classified nuclear warfare project...
  84. ncbi Aims of conditioning
    Huib M Vriesendorp
    Exp Hematol 31:844-54. 2003
    b>Nuclear warfare research and treatment of radiation accident victims uncovered the potential of hemopoietic stem cell transplants...
  85. ncbi Amifostine: chemotherapeutic and radiotherapeutic protective effects
    V Santini
    Dept of Haematology, Policlinico di Careggi, Viale Morgagni 85, 50134 Firenze, Italy
    Expert Opin Pharmacother 2:479-89. 2001
    ..Amifostine was originally developed as a radioprotective agent in a classified nuclear warfare project...
  86. ncbi Manhattan transfer: lethal radiation, bone marrow transplantation, and the birth of stem cell biology, ca. 1942-1961
    Alison Kraft
    Inst for Science and Society, Univ of Nottingham
    Hist Stud Nat Sci 39:171-218. 2009
    This study investigates how, in the late 1940s and 1950s, fears of nuclear accidents and nuclear warfare shaped postwar radiobiology...
  87. ncbi Cardiovascular function in breast cancer patients receiving radiotherapy
    C N Anigbogu
    Department of Physiology, Radiotherapy Radiation Biology, College of Medicine, University of Lagos, Idi Araba, 101014 Nigeria
    Nig Q J Hosp Med 18:21-4. 2008
    ..may be for medicinal, industrial or cosmetic purposes and sometimes accidental and incidental exposure as in nuclear warfare. Cardiovascular function was studied in some female patients with breast cancer undergoing radiation therapy...
  88. ncbi Anomalous 235U/238U ratios and metal elements detected in the black rain from the Hiroshima A-bomb
    Yoko Fujikawa
    Research Reactor Institute, Kyoto University, Kumatori cho, Sennan gun, Osaka 590 0494, Japan
    Health Phys 84:155-62. 2003
    Contents of black rain from the A-bomb are important to clarify the health and environmental hazard caused by nuclear warfare. We analyzed the only existing physical remains of the black rain from Hiroshima A-bomb (Little Boy), a ..
  89. ncbi Shielding from solar particle event exposures in deep space
    J W Wilson
    NASA Langley Research Center, Hampton, VA 23681 0001, USA
    Radiat Meas 30:361-82. 1999
    ..experienced by sensitive tissues and used to evaluate bioresponse models developed for use in tactical nuclear warfare. The present results will help to clarify the biophysical aspects of such exposure in the assessment of RBE ..
  90. ncbi Psychological effects of nuclear and radiological warfare
    C A Salter
    Medical Service Corps, Military Medical Operations Department, Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20889, USA
    Mil Med 166:17-8. 2001
    Not since 1945 has the world experienced nuclear warfare, although there has been the threat of nuclear terrorism and a large number of nuclear/radiological accidents...
  91. ncbi In vivo EPR dosimetry to quantify exposures to clinically significant doses of ionising radiation
    Harold M Swartz
    EPR Center for Viable Systems, Dartmouth Medical School, 703 Vail, Hanover, NH 03755, USA
    Radiat Prot Dosimetry 120:163-70. 2006
    ..state of development, the method is already sufficient for decision-making action for individuals with regard to acute effects from exposure to ionising radiation for most applications related to terrorism, accidents or nuclear warfare.
  92. ncbi Measurements of clinically significant doses of ionizing radiation using non-invasive in vivo EPR spectroscopy of teeth in situ
    Harold M Swartz
    Dartmouth Medical School, EPR Center for Viable Systems, Hanover, NH 03755, USA
    Appl Radiat Isot 62:293-9. 2005
    ..In its current state of development, it probably is sufficient for most applications related to terrorism or nuclear warfare, for decision-making for action for individuals in regard to acute effects from exposure to ionizing radiation...
  93. pmc The incidence of leukemia, lymphoma and multiple myeloma among atomic bomb survivors: 1950-2001
    Wan Ling Hsu
    Radiation Effects Research Foundation, Hiroshima and Nagasaki, Japan
    Radiat Res 179:361-82. 2013
    ..There was no evidence of radiation-associated excess risks for either Hodgkin lymphoma or multiple myeloma...
  94. ncbi Manmade and natural radionuclides in north east Atlantic shelf and slope sediments: Implications for rates of sedimentary processes and for contaminant dispersion
    A B MacKenzie
    Scottish Universities Environmental Research Centre, Scottish Enterprise Technology Park, East Kilbride, G75 0QF, Scotland, UK
    Sci Total Environ 369:256-72. 2006
    ..By analogy, it can be concluded that a similar situation will apply to other contaminants in seawater entering the north east Atlantic via the North Channel...
  95. ncbi Chemical, biological and radiation casualties: critical care considerations
    S A Bland
    Emergency Medicine, Queen Alexandra Hospital, Portsmouth
    J R Army Med Corps 155:160-71. 2009
    ..Critical care departments should also contingency plans for CBRN events including surge capacity...
  96. ncbi Risks of brain tumour following treatment for cancer in childhood: modification by genetic factors, radiotherapy and chemotherapy
    M P Little
    National Radiological Protection Board, Chilton, Didcot, Oxon, UK
    Int J Cancer 78:269-75. 1998
    ....
  97. ncbi Enhanced neoplastic transformation by mammography X rays relative to 200 kVp X rays: indication for a strong dependence on photon energy of the RBE(M) for various end points
    D Frankenberg
    Department for Clinical Radiobiology and Clinical Radiation Physics, University of Gottingen, von Siebold Strasse 3, D 37075 Gottingen, Germany
    Radiat Res 157:99-105. 2002
    ....
  98. pmc Are A-bomb survivor studies an appropriate basis for nuclear worker compensation?
    David Richardson
    Environ Health Perspect 111:A748. 2003
  99. ncbi The politics of atmospheric sciences: "nuclear winter" and global climate change
    Matthias Dörries
    IRIST, Universite de Strasbourg, 7 rue de l Universite, 67000 Strasbourg, France
    Osiris 26:198-223. 2011
    ..This story foreshadows that of recent research on anthropogenic climate change, which was substantially shaped during this--apparently tangential--cold war debate of the 1980s about research on the global effects of nuclear weapons...
  100. pmc Neocortical neurogenesis in humans is restricted to development
    Ratan D Bhardwaj
    Department of Cell and Molecular Biology, Medical Nobel Institute, and Department of Forensic Medicine, Karolinska Institute, SE 171 77 Stockholm, Sweden
    Proc Natl Acad Sci U S A 103:12564-8. 2006
    ....
  101. ncbi Radionuclide release and transport from nuclear underground tests performed at Mururoa and Fangataufa--predictions under uncertainty
    W Pfingsten
    Paul Scherrer Institute PSI, CH 5232 Villigen, Switzerland
    J Contam Hydrol 47:349-63. 2001
    ..In view of the lack and uncertainty of site-specific data, the agreement is of acceptable quality...

Research Grants32

  1. Protectan CBLB502
    Andrei Gudkov; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): The growing threats of nuclear warfare and terrorism highlight the need to develop effective and non-toxic radiation countermeasures that can increase survival of ARS victims and alleviate post-..
  2. HIGH ENERGY IONS AND GENOMIC INSTABILITY
    Eric Hall; Fiscal Year: 2001
    ....
  3. KIDNEY RESPONSE TO RADIATION AND CHEMOTHERAPY
    JOHN MOULDER; Fiscal Year: 2006
    ..unreadable] 4) Complete the randomized, prospective, trial of the use of ACE inhibitors to prevent the development of radiation nephropathy in BMT patients. [unreadable] [unreadable]..
  4. Near infrared/MR system for imaging brain oxygenation
    Harold Swartz; Fiscal Year: 2004
    ..This grant will produce a novel imaging modality which can non-invasively monitor cerebral oxygenation, structure, and blood flow. ..
  5. Determination of Clinical Feasibility of EPR Oximetry of Tumors
    Harold Swartz; Fiscal Year: 2007
    ..Determining the feasibility of continuous measurements for up to 120 minutes. [unreadable] [unreadable] [unreadable]..
  6. BioDose-08 Conference
    Harold Swartz; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  7. Measurement of pO2 in tissues in vivo and in vitro
    Harold Swartz; Fiscal Year: 2006
    ....
  8. Development of a Diagnostic Test for Alzheimer's Disease
    Mark Lovell; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  9. Neuronogenesis in the Non-pigmented Retina
    RICHARD NOWAKOWSKI; Fiscal Year: 2008
    ..Such detailed information is important for understanding how the lack of retinal pigment produces abnormalities and for the rationale development of treatments and therapies. ..
  10. Cardiovascular Risk 50 Years After Thymic Irradiation
    Michael Adams; Fiscal Year: 2007
    ..This group of individuals, if shown to be at high risk, constitutes a potentially huge number of persons who may benefit from additional preventive measures. ..
  11. Treatment and Costs of Neonatal Jaundice in a Large HMO
    Thomas Newman; Fiscal Year: 2007
    ..The results of this study will help make neonatal jaundice guidelines and treatment decisions more evidence based. [unreadable] [unreadable] [unreadable]..
  12. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2009
    ..such as parity and body mass index, modify this association?;and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  13. Thyroid Disease in People Exposed to Radioactive Fallout
    JOSEPH LYON; Fiscal Year: 2004
    ..Abstract not provided ..
  14. Eliciting Truly Informed Consent
    William Hendee; Fiscal Year: 2003
    ..abstract_text> ..
  15. Assay for detection of cancer chromosome abnormalities
    Tore Straume; Fiscal Year: 2002
    ..g. designed for use with kits); and instrumentation designed for fieldable assay formats. ..
  16. Mechanistic models in occupational cancer epidemiology
    David Richardson; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  17. MECHANISMS OF ENZYMIC AND HYDRIDE TRANSFERS
    Gregory Petsko; Fiscal Year: 2006
    ..abstract_text> ..
  18. RADIOBIOLOGY OF D RADIODURANS--GENETIC APPROACH
    Michael Daly; Fiscal Year: 2001
    ..These studies will delineate the genetics and biochemistry of radioresistance in D. radiodurans. Insight into its strategies may have broad implications for understanding radioresistance and DSB-metabolism throughout nature. ..
  19. Genetic Consequences of Therapies for Cancer
    John Boice; Fiscal Year: 2009
    ..abstract_text> ..
  20. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  21. c-erbB-2 and Risk of Contralateral Breast Cancer
    Christopher Li; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  22. Community Health Effects of Industrial Hog Operations
    Steven Wing; Fiscal Year: 2005
    ....
  23. AGRICULTURAL DUST AND CHILDHOOD ASTHMA SYMPTOMS
    Steve Wing; Fiscal Year: 2004
    ....
  24. COMMUNITY HEALTH & ENVIRONMENTAL REAWAKENING
    Steven Wing; Fiscal Year: 2007
    ....
  25. Phenomic analysis of the murine hippocampus
    RICHARD NOWAKOWSKI; Fiscal Year: 2007
    ..This "moderate throughput" approach, in effect, provides a genetic dissection of hippocampal structure, function, and development [unreadable] [unreadable]..
  26. Time-Factors in Exposure Effects Among Uranium Workers
    David Richardson; Fiscal Year: 2003
    ....