lipomatosis

Summary

Summary: A disorder characterized by the accumulation of encapsulated or unencapsulated tumor-like fatty tissue resembling LIPOMA.

Top Publications

  1. Padwa B, Mulliken J. Facial infiltrating lipomatosis. Plast Reconstr Surg. 2001;108:1544-54 pubmed
    Facial infiltrating lipomatosis is a rare congenital disorder in which mature lipocytes invade adjacent tissue. The phenotypic features include soft-tissue and skeletal hypertrophy, premature dental eruption, and regional macrodontia...
  2. Siva C, Brasington R, Totty W, Sotelo A, Atkinson J. Synovial lipomatosis (lipoma arborescens) affecting multiple joints in a patient with congenital short bowel syndrome. J Rheumatol. 2002;29:1088-92 pubmed
    Synovial lipomatosis is a rare, synovial based disorder that typically affects a single knee...
  3. Bodas A, Rivilla F, Maluenda C. Intestinal lipomatosis in a 10-year-old girl. Eur J Pediatr. 2008;167:601-2 pubmed
  4. Raeder H, Haldorsen I, Ersland L, Grüner R, Taxt T, Søvik O, et al. Pancreatic lipomatosis is a structural marker in nondiabetic children with mutations in carboxyl-ester lipase. Diabetes. 2007;56:444-9 pubmed
    Both pancreatic volume reduction and lipomatosis have been observed in subjects with diabetes...
  5. Valera E, Brassesco M, Scrideli C, de Castro Barros M, Santos A, Oliveira R, et al. Are patients with encephalocraniocutaneous lipomatosis at increased risk of developing low-grade gliomas?. Childs Nerv Syst. 2012;28:19-22 pubmed publisher
    ..We describe two pediatric patients with encephalocraniocutaneous lipomatosis (ECCL), a very rare genetic syndrome with around 60 reported cases, which developed low-grade astrocytoma at 3 ..
  6. Woodhouse J, Delahunt B, English S, Fraser H, Ferguson M. Testicular lipomatosis in Cowden's syndrome. Mod Pathol. 2005;18:1151-6 pubmed
    ..The high incidence of testicular lipomatosis in our adult subjects suggests this to be an important diagnostic criterion for Cowden's syndrome.
  7. Chang S, Coakley F, Goldstein R. Case report: Renal replacement lipomatosis associated with renal transplantation. Br J Radiol. 2005;78:60-1 pubmed
    We report a case of extensive renal replacement lipomatosis demonstrated by ultrasound (US) and computed tomography (CT) in a 57-year-old woman with a history of two cadaveric renal transplants...
  8. Lopez Gonzalez A, Resurrección Giner M. Idiopathic spinal epidural lipomatosis: urgent decompression in an atypical case. Eur Spine J. 2008;17 Suppl 2:S225-7 pubmed
    Symptomatic spinal epidural lipomatosis (SEL) is very rare and frequently associated to chronic exogenous steroid use, obesity and Cushing syndrome...
  9. Suárez Moreno R, Hernández Ramírez D, Madrazo Navarro M, Salazar Lozano C, Martínez Gen R. Multiple intestinal lipomatosis. Case report. Cir Cir. 2010;78:163-5 pubmed
    Intestinal lipomatosis is a rare disease with an incidence at autopsy ranging from 0.04 to 4.5%. Few cases have been reported in the medical literature. The condition is usually asymptomatic...

More Information

Publications61

  1. Gokhale N, Mahajan P, Belgaumkar V, Pradhan S, Uttarwar N. Encephalocraniocutaneous lipomatosis: a rare neurocutaneous syndrome. Indian J Dermatol Venereol Leprol. 2007;73:40-2 pubmed
    Encephalocraniocutaneous lipomatosis is a congenital hamartomatous disorder with unique ocular, cutaneous and neurological features. A 13-year-old boy presented with history of mental retardation and delayed developmental milestones...
  2. Unal S, Demirkan F, Arslan E, Cinel L. Infiltrating lipomatosis of the face: a case report and review of the literature. J Oral Maxillofac Surg. 2003;61:1098-101 pubmed
  3. Woodhouse J, Ferguson M. Multiple hyperechoic testicular lesions are a common finding on ultrasound in Cowden disease and represent lipomatosis of the testis. Br J Radiol. 2006;79:801-3 pubmed
    ..These lesions in Cowden's patients represent a newly described testicular pathology - lipomatosis of the testis. Here we detail the radiological findings...
  4. Phi J, Park S, Chae J, Wang K, Cho B, Kim S. Papillary glioneuronal tumor present in a patient with encephalocraniocutaneous lipomatosis: case report. Neurosurgery. 2010;67:E1165-9 pubmed publisher
    Encephalocraniocutaneous lipomatosis (ECCL) is a rare neurocutaneous syndrome presumably derived from a mesenchymal defect. No cases of ECCL associated with a neuroepithelial brain tumor have been described...
  5. Watt A, Chung K. Macrodystrophia lipomatosa: a reconstructive approach to gigantism of the foot. J Foot Ankle Surg. 2004;43:51-5 pubmed
    ..The 3 procedures debulked the foot for normal ambulation and same-size shoe wear for both feet. The resulting functional and aesthetic improvements achieved through reconstructive treatment provided a desirable alternative to amputation...
  6. Toy B. Familial multiple lipomatosis. Dermatol Online J. 2003;9:9 pubmed
    Familial multiple lipomatosis is a rare hereditary syndrome with a proposed autosomal-dominant inheritance. A case of an 89-year-old man with this disease is presented, along with his pedigree...
  7. Kiris A, Kocakoc E, Poyraz A, Dagli F, Boztosun Y. Xanthogranulomatous pyelonephritis with nephrocutanous fistula and coexisting renal replacement lipomatosis: the report of a rare case. Clin Imaging. 2005;29:356-8 pubmed
    Renal replacement lipomatosis (RRL) is the result of rare, usually unilateral, and severe atrophy and destruction of the renal parenchyma often caused by renal calculi...
  8. Kozanoglu E, Koc F, Goncu K. Macrodystrophia lipomatosa with multiple entrapment neuropathies: a case report. Int J Neurosci. 2008;118:545-53 pubmed publisher
  9. Ettl T, Gaumann A, Ehrenberg R, Reichert T, Driemel O. Encapsulated lipomas of the tongue in benign symmetric lipomatosis. J Dtsch Dermatol Ges. 2009;7:441-4 pubmed publisher
    Benign symmetric lipomatosis (Madelung disease) is a rare disorder of unknown etiology characterized by diffuse growth of unencapsulated lipomas predominantly in the head, neck and shoulder region...
  10. Rathoriya R, Shrivastava J. Encephalocraniocutaneous lipomatosis. Indian Pediatr. 2006;43:262-3 pubmed
  11. Myers K, Davies S, Shimamura A. Clinical and molecular pathophysiology of Shwachman-Diamond syndrome: an update. Hematol Oncol Clin North Am. 2013;27:117-28, ix pubmed publisher
    ..This article summarizes the clinical phenotype of SDS, diagnostic and treatment approaches, and novel advances in our understanding of the molecular pathophysiology of this disease...
  12. Hauber K, Warmuth Metz M, Rose C, Bröcker E, Hamm H. Encephalocraniocutaneous lipomatosis: a case with unilateral odontomas and review of the literature. Eur J Pediatr. 2003;162:589-93 pubmed
    We report a 7-year-old boy with the typical features of encephalocraniocutaneous lipomatosis (ECCL) including unilateral skin, eye, bone, and asymptomatic central nervous system involvement...
  13. Couto R, Mulliken J, Padwa B, Hassanein A, Rogers G, Kulungowski A, et al. Facial infiltrating lipomatosis: expression of angiogenic and vasculogenic factors. J Craniofac Surg. 2011;22:2405-8 pubmed publisher
    Facial infiltrating lipomatosis causes diffuse overgrowth of subcutaneous fat, muscle, and bone...
  14. Ozturk A, Baktiroglu L, Ozturk E, Yazgan P. [Macrodystrophia lipomatosa: a case report]. Acta Orthop Traumatol Turc. 2004;38:220-3 pubmed
    ..The patient had no complaints and there was no change in the size of the lesion within a two-year follow-up period. ..
  15. Cultrera F, Guarnera F, Giardina M. Overlap among neurocutaneous syndromes. Observations on encephalocraniocutaneous lipomatosis. Minerva Pediatr. 2004;56:219-22 pubmed
    The authors report a case of encephalocraniocutaneous lipomatosis (ECCL) in a female infant...
  16. Sakata Y, Kinoshita N, Kato H, Yamada Y, Sugimura Y. Coexistence of renal replacement lipomatosis with xanthogranulomatous pyelonephritis. Int J Urol. 2004;11:44-6 pubmed
    We report on a case of coexistence of replacement lipomatosis with xanthogranulomatous pyelonephritis (XGP) in the same kidney associated with staghorn calculi...
  17. Andreadis D, Rizos C, Belazi M, Peneva M, Antoniades D. Encephalocraniocutaneous lipomatosis accompanied by maxillary compound odontoma and juvenile angiofibroma: report of a case. Birth Defects Res A Clin Mol Teratol. 2004;70:889-91 pubmed
    Encephalocraniocutaneous lipomatosis (ECCL) is a rare neurocutaneous syndrome characterized by congenital cutaneous, ocular, and neurologic abnormalities, which may be pronounced in the head and neck.
  18. Botwin K, Sakalkale D. Epidural steroid injections in the treatment of symptomatic lumbar spinal stenosis associated with epidural lipomatosis. Am J Phys Med Rehabil. 2004;83:926-30 pubmed
    Epidural lipomatosis has been implicated as a cause or contributor of symptomatic lumbar spinal stenosis...
  19. Herbst K. Rare adipose disorders (RADs) masquerading as obesity. Acta Pharmacol Sin. 2012;33:155-72 pubmed publisher
    Rare adipose disorders (RADs) including multiple symmetric lipomatosis (MSL), lipedema and Dercum's disease (DD) may be misdiagnosed as obesity...
  20. Campen R, Sang C, Duncan L. Case records of the Massachusetts General Hospital. Case 25-2006. A 41-year-old woman with painful subcutaneous nodules. N Engl J Med. 2006;355:714-22 pubmed
  21. Haloi A, Ditchfield M, Penington A, Phillips R. Facial infiltrative lipomatosis. Pediatr Radiol. 2006;36:1159-62 pubmed
    Although there are multiple case reports and small series concerning facial infiltrative lipomatosis, there is no composite radiological description of the condition...
  22. Lee B, Song K. Calcified chronic pericardial fat necrosis in localized lipomatosis of pericardium. AJR Am J Roentgenol. 2007;188:W21-4 pubmed
  23. Herbst K, Coviello A, Chang A, Boyle D. Lipomatosis-associated inflammation and excess collagen may contribute to lower relative resting energy expenditure in women with adiposis dolorosa. Int J Obes (Lond). 2009;33:1031-8 pubmed publisher
    Adiposis dolorosa (AD) is a syndrome of obese and non-obese individuals whose hallmark is lipomatosis: unencapsulated painful fatty masses in subcutaneous fat. Lipomatosis may contain excess collagen and multi-nucleated giant (MNG) cells...
  24. Dror Y, Donadieu J, Koglmeier J, Dodge J, Toiviainen Salo S, Makitie O, et al. Draft consensus guidelines for diagnosis and treatment of Shwachman-Diamond syndrome. Ann N Y Acad Sci. 2011;1242:40-55 pubmed publisher
    ..Whenever possible, evidence-based conclusions are made, but as with other rare diseases, the data on SDS are often anecdotal. The authors welcome comments from readers...
  25. Caux F, Plauchu H, Chibon F, Faivre L, Fain O, Vabres P, et al. Segmental overgrowth, lipomatosis, arteriovenous malformation and epidermal nevus (SOLAMEN) syndrome is related to mosaic PTEN nullizygosity. Eur J Hum Genet. 2007;15:767-73 pubmed
    ..and congenital dysmorphisms including segmental overgrowth, arteriovenous and lymphatic vascular malformations, lipomatosis and linear epidermal nevus reminiscent of the diagnosis of Proteus syndrome...
  26. Sanal H, Kocaoglu M, Yildirim D, Ors F. Multiple cardiac lipomas and pericardial lipomatosis: multidedector-row computer tomography findings. Int J Cardiovasc Imaging. 2007;23:655-8 pubmed
    ..tomography (MDCT) findings of a nontuberosclerosis case with multiple cardiac lipomas along with pericardial lipomatosis, who presented with symptoms of left heart failure after a hysterectomy surgery but otherwise healthy before ..
  27. Tok C, Kaur S, Gangi A. Symptomatic spinal epidural lipomatosis after a single local epidural steroid injection. Cardiovasc Intervent Radiol. 2011;34 Suppl 2:S250-5 pubmed publisher
    Spinal epidural lipomatosis is a rare disorder that can manifest with progressive neurological deficits...
  28. Hooten W, Hogan M, Sanemann T, Maus T. Acute spinal pain during an attempted lumbar epidural blood patch in congenital lumbar spinal stenosis and epidural lipomatosis. Pain Physician. 2008;11:87-90 pubmed
    ..Unrecognized congenital lumbar spinal stenosis is an important addition to the differential diagnosis of acute radicular pain elicited during an epidural blood patch in previously asymptomatic patients. ..
  29. Burwick N, Coats S, Nakamura T, Shimamura A. Impaired ribosomal subunit association in Shwachman-Diamond syndrome. Blood. 2012;120:5143-52 pubmed publisher
    ..In summary, we demonstrate an SBDS-dependent ribosome maturation defect in SDS patient cells. The role of ribosomal subunit joining in marrow failure warrants further investigation...
  30. Moog U. Encephalocraniocutaneous lipomatosis. J Med Genet. 2009;46:721-9 pubmed publisher
    Encephalocraniocutaneous lipomatosis (ECCL) is a sporadically occurring neurocutaneous disorder of unknown aetiology. It has repeatedly been discussed as a localised form of Proteus syndrome...
  31. Moller J, Girschick H, Hahn G, Pessler F. [Steroid-induced spinal epidural lipomatosis in pediatric patients]. Z Rheumatol. 2010;69:447-9 pubmed publisher
    ..In all cases, MRI showed extensive spinal epidural lipomatosis, a rare but classic untoward effect of chronic glucocorticoid therapy...
  32. Geers C, Lecouvet F, Behets C, Malghem J, Cosnard G, Lengelé B. Polygonal deformation of the dural sac in lumbar epidural lipomatosis: anatomic explanation by the presence of meningovertebral ligaments. AJNR Am J Neuroradiol. 2003;24:1276-82 pubmed
    In patients with epidural lipomatosis, axial lumbar spine CT and MR images occasionally reveal a geometric, polygonal or stellar, shape of the dural sac...
  33. Laouad I, Buchler M, Weestel P, Lebranchu Y, Legendre C, Choukroun G, et al. Replacement kidney lipomatosis after renal transplantation. Transplantation. 2005;79:496-8 pubmed
    Renal sinus lipomatosis consists of abnormal fatty proliferation of the renal sinus, hilus, and perirenal spaces...
  34. Prasad K, Pandey R, Kathuria M, Pradhan P. Co-existent massive renal replacement lipomatosis and xanthogranulomatous pyelonephritis--a case report. Indian J Pathol Microbiol. 2003;46:674-5 pubmed
    Renal replacement lipomatosis is a benign condition that may assume major clinical significance by producing pyelocalyceal deformities that may be mistaken for true renal masses...
  35. Tuzuner T, Parlak A, Kavak A, Alper M. A neglected case of macrodystrophia lipomatosa of the foot in an elderly man. J Am Podiatr Med Assoc. 2005;95:486-90 pubmed
    ..As such, it may advance current knowledge of macrodystrophia lipomatosa. Special emphasis is given to the unique "bridge" formation seen radiographically in this case. ..
  36. Furquim I, Honjo R, Bae R, Andrade W, Santos M, Tannuri U, et al. Proteus syndrome: report of a case with recurrent abdominal lipomatosis. J Pediatr Surg. 2009;44:E1-3 pubmed publisher
    ..Nevertheless, among the internal lipomas, abdominal lipomatosis is rare (3), with less than 15 cases reported...
  37. Boybeyi O, Alanay Y, Kayikcioglu A, Karnak I. Hemihyperplasia-multiple lipomatosis syndrome: an underdiagnosed entity in children with asymmetric overgrowth. J Pediatr Surg. 2010;45:E19-23 pubmed publisher
    ..This report describes 2 patients with hemihyperplasia-multiple lipomatosis syndrome. The finding of hemihyperplasia prompts careful examination for associated lipomatous lesions...
  38. Akhtar A, D Cruz I, Ramanathan K, Umpierrez M. Diffuse locally invasive lipomatosis of the pericardium. Echocardiography. 2003;20:173-7 pubmed
    ..MRI, CT and cardiac catheterization findings in a 72-year-old patient with extensive pericardial lipomatosis are presented. Diastolic pressures in the left heart were elevated...
  39. Shenoy R, Rodrigues G, Gopashetty M, Kannaiyan L, Rao S. Segmental jejunal lipomatosis--a rare cause of intestinal obstruction. Yonsei Med J. 2003;44:359-61 pubmed
    A rare case of a segmental small intestinal (jejunal) lipomatosis is described. A 33-year-old male was admitted with a clinical diagnosis of an acute intestinal obstruction. A plain erect abdominal x-ray showed multiple air-fluid levels...
  40. Porras Estrada L, Díaz Pérez de Madrid J, Cabezudo Artero J, Lorenzana Honrado L, Rodríguez Sánchez J, Ugarriza Echebarrieta F. [Spinal extradural lipomatosis. Revision of 108 cases. Case induced by exogenous contribution of ACTH]. Neurocirugia (Astur). 2002;13:463-71; discussion 472 pubmed
    Authors present a male patient with Spinal Extradural Lipomatosis, previously treated of a cerebral astrocytoma with surgery and radiotherapy, after which he received ACTH for a long period of time...
  41. Rubegni P, Risulo M, Sbano P, Buonocore G, Perrone S, Fimiani M. Encephalocraniocutaneous lipomatosis (Haberland syndrome) with bilateral cutaneous and visceral involvement. Clin Exp Dermatol. 2003;28:387-90 pubmed
    Encephalocraniocutaneous lipomatosis, or Haberland syndrome, is a rare congenital neurocutaneous disease...
  42. Ly J, Beall D. Quiz case. Macrodystrophia lipomatosa. Eur J Radiol. 2003;47:16-8 pubmed
  43. Keskin D, Ezirmik N, Celik H. Familial multiple lipomatosis. Isr Med Assoc J. 2002;4:1121-3 pubmed
    Familial multiple lipomatosis is an extremely rare disease. The disease usually does not affect the daily life of FML victims, but they may experience difficulty in performing everyday physical tasks if the lipomas are multiple and large...
  44. Ohta Y, Hayashi T, Sasaki C, Shiote M, Manabe Y, Shoji M, et al. Cauda equina syndrome caused by idiopathic sacral epidural lipomatosis. Intern Med. 2002;41:593-4 pubmed
    The patient, who was a non-obese woman with no predisposing conditions of lipomatosis, slowly developed cauda equina syndrome...
  45. Taille C, Fartoukh M, Houel R, Kobeiter H, Remy P, Lemaire F. Spontaneous hemomediastinum complicating steroid-induced mediastinal lipomatosis. Chest. 2001;120:311-3 pubmed
    ..case of a patient with systemic lupus erythematosus, nephrotic syndrome, and renal failure, in whom mediastinal lipomatosis (ML) developed following increased corticosteroid therapy...
  46. Xu Y, Liu R, Zhang Z, Zhao W, Yang Q. Renal replacement lipomatosis. Eur Surg Res. 2006;38:385-7 pubmed
    We report a relatively rare case of renal replacement lipomatosis presenting as a renal mass...
  47. Delfino L, Fariello G, Quattrocchi C, Aiello C, Menchini L, Devito R, et al. Encephalocraniocutaneous lipomatosis (ECCL): neuroradiological findings in three patients and a new association with fibrous dysplasia. Am J Med Genet A. 2011;155A:1690-6 pubmed publisher
    Encephalocraniocutaneous lipomatosis (ECCL) is a rare neurocutaneous syndrome characterized by involvement of tissues of ectodermal and mesodermal origin such as skin, eye, adipose tissue, and brain...
  48. Kamo M, Watanabe Y, Numaguchi Y, Saida Y. Spinal subdural hematoma mimicking epidural lipomatosis. Magn Reson Med Sci. 2012;11:197-9 pubmed
    ..in the spinal canal on both T?- and T?-weighted images, findings closely resembling those for epidural lipomatosis. Identification of 2-layered signal intensity surrounding the cauda equina on axial images is the key for ..
  49. Zuppani H, Guedes B, da Silva C, da Rocha A. Lipomyelocele with osseous dysraphic hamartoma in a child: a case report. J Pediatr Orthop B. 2010;19:382-4 pubmed publisher
    ..We reviewed the role of magnetic resonance and computed tomography with tridimensional reconstruction in this rare form of spinal dysraphism and described the imaging features. ..
  50. Conde Taboada A, Mayo E, Gonzalez B, Pardavila R, De la Torre C, Cruces M. Hypertrophic infantile pedal papules. Pediatr Dermatol. 2007;24:339-40 pubmed
  51. Kano K, Kyo K, Ito S, Nishikura K, Ando T, Yamada Y, et al. Spinal epidural lipomatosis in children with renal diseases receiving steroid therapy. Pediatr Nephrol. 2005;20:184-9 pubmed
    Spinal epidural lipomatosis (SEL) in patients on steroid therapy may be explained by two hypotheses: (1) steroids induce SEL and (2) steroids cause the growth of a pre-existing SEL, especially in obese children...
  52. Levy M, MASSEY C. Encephalocraniocutaneous lipomatosis. Handb Clin Neurol. 2015;132:265-9 pubmed publisher
    Encephalocraniocutaneous lipomatosis (ECCL) is an unusual condition marked by characteristic dermatologic and neurologic findings presenting in a mosaic fashion. These are now being found to be due to specific genetic mutations...