Summary: Excretion of abnormally high level of CALCIUM in the URINE, greater than 4 mg/kg/day.

Top Publications

  1. Dawson C, Tomson C. Kidney stone disease: pathophysiology, investigation and medical treatment. Clin Med (Lond). 2012;12:467-71 pubmed
  2. Nadarajah L, Khosravi M, Dumitriu S, Klootwijk E, Kleta R, Yaqoob M, et al. A novel claudin-16 mutation, severe bone disease, and nephrocalcinosis. Lancet. 2014;383:98 pubmed publisher
  3. Aloia J, Shieh A, Mikhail M, Islam S. Urinary calcium excretion in postmenopausal African American women. Clin Nephrol. 2015;84:130-7 pubmed publisher
    ..Urine calcium excretion is lower in postmenopausal African American than White women. The reference range developed should be considered in the diagnosis of hypocalciuric states and may also be useful in the diagnosis of hypercalciuria.
  4. Neisius A, Preminger G. Stones in 2012: epidemiology, prevention and redefining therapeutic standards. Nat Rev Urol. 2013;10:75-7 pubmed publisher
  5. Ephraim R, Osakunor D, Denkyira S, Eshun H, Amoah S, Anto E. Serum calcium and magnesium levels in women presenting with pre-eclampsia and pregnancy-induced hypertension: a case-control study in the Cape Coast metropolis, Ghana. BMC Pregnancy Childbirth. 2014;14:390 pubmed publisher
    ..Mineral supplementation during the antenatal period may influence significantly, the occurrence of hypertensive disorders in pregnancy. ..
  6. Gross I, Siedner Weintraub Y, Simckes A, Gillis D. Antenatal Bartter syndrome presenting as hyperparathyroidism with hypercalcemia and hypercalciuria: a case report and review. J Pediatr Endocrinol Metab. 2015;28:943-6 pubmed publisher
    ..is usually identified by the presence of polyhydramnios, premature delivery, hypokalemia, metabolic alkalosis, hypercalciuria, and nephrocalcinosis caused by mutations in the Na-K-2Cl cotransporter (NKCC2)-encoding SLC12A1 gene...
  7. Ubetagoyena Arrieta M, Martínez Sáenz de Jubera J, Corera Casty M, González Pérez Yarza E, García Albizua I. Physicochemical factors of the urine of children with hypercalciuria. Arch Esp Urol. 2017;70:342-348 pubmed
    b>Hypercalciuria is a common lithogenic risk factor...
  8. Pillar N, Pleniceanu O, Fang M, Ziv L, Lahav E, Botchan S, et al. A rare variant in the FHL1 gene associated with X-linked recessive hypoparathyroidism. Hum Genet. 2017;136:835-845 pubmed publisher
    ..Altogether, our data suggest that FHL1 is a novel regulator of calcium homeostasis and implicate it as the causative gene for X-linked recessive hypoparathyroidism. ..
  9. Nilsson I, Norenstedt S, Zedenius J, Pernow Y, Bränström R. Primary hyperparathyroidism, hypercalciuria, and bone recovery after parathyroidectomy. Surgery. 2017;162:429-436 pubmed publisher
    ..Our aim was to further explore the relationship between hypercalciuria, kidney function, and bone recovery after parathyroidectomy...

More Information


  1. Sawicka Kamińska A, Szymanik Grzelak H, Szymanik Grzelak M. [The long-term results of the treatment of renal hypercalciuria - a report of two cases]. Pol Merkur Lekarski. 2017;42:260-263 pubmed
    ..In most cases it is possible to diagnose metabolic abnormalities, of which the most frequent is hypercalciuria (excessive excretion of calcium in urine). In children, idiopathic hypercalciuria occurs the most frequently...