motion sickness

Summary

Summary: Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness.

Top Publications

  1. Buyuklu F, Tarhan E, Ozluoglu L. Vestibular functions in motion sickness susceptible individuals. Eur Arch Otorhinolaryngol. 2009;266:1365-71 pubmed publisher
    There exists no functional guide that can serve as a diagnostic tool for individual susceptibility to motion sickness (MS)...
  2. Shupak A, Gordon C. Motion sickness: advances in pathogenesis, prediction, prevention, and treatment. Aviat Space Environ Med. 2006;77:1213-23 pubmed
    b>Motion sickness has a major influence on modern traveling activities and the rapidly spreading engagement in virtual reality immersion...
  3. Lackner J, DiZio P. Space motion sickness. Exp Brain Res. 2006;175:377-99 pubmed
    b>Motion sickness remains a persistent problem in spaceflight. The present review summarizes available knowledge concerning the incidence and onset of space motion sickness and aspects of the physiology of motion sickness...
  4. Vitkovic J, Paine M, Rance G. Neuro-otological findings in patients with migraine- and nonmigraine-related dizziness. Audiol Neurootol. 2008;13:113-22 pubmed
  5. Horing B, Weimer K, Schrade D, Muth E, Scisco J, Enck P, et al. Reduction of motion sickness with an enhanced placebo instruction: an experimental study with healthy participants. Psychosom Med. 2013;75:497-504 pubmed publisher
    Expectancy and conditioning are underlying mechanisms of placebo and nocebo responses. In previous studies with motion sickness, we could induce nocebo responses by both methods, but no placebo responses.
  6. Drummond P. Triggers of motion sickness in migraine sufferers. Headache. 2005;45:653-6 pubmed
    To determine whether susceptibility to motion sickness provoked by unexpected movement is associated with susceptibility to visually induced motion sickness in migraine sufferers.
  7. D Souza W, Malinowski K, Van Liew S, D Souza G, Asbury K, McAvoy T, et al. Investigation of motion sickness and inertial stability on a moving couch for intra-fraction motion compensation. Acta Oncol. 2009;48:1198-203 pubmed publisher
    ..The purpose of this work was to investigate motion sickness and stability of the patient's external surface due to a moving couch with respiration-comparable velocities ..
  8. Arshian M, Puterbaugh S, Miller D, Catanzaro M, Hobson C, McCall A, et al. Effects of visceral inputs on the processing of labyrinthine signals by the inferior and caudal medial vestibular nuclei: ramifications for the production of motion sickness. Exp Brain Res. 2013;228:353-63 pubmed publisher
    ..Consequently, it has been hypothesized that neurons in the caudal vestibular nuclei participate in triggering motion sickness and that visceral inputs to the vestibular nucleus complex can affect motion sickness susceptibility...
  9. Smart L, Stoffregen T, Bardy B. Visually induced motion sickness predicted by postural instability. Hum Factors. 2002;44:451-65 pubmed
    We investigated whether postural instability can predict motion sickness and studied relations among instability, motion sickness, and vection. Nine men and 4 women (mean age = 19...

More Information

Publications62

  1. Dai M, Raphan T, Cohen B. Prolonged reduction of motion sickness sensitivity by visual-vestibular interaction. Exp Brain Res. 2011;210:503-13 pubmed publisher
    ..frequencies to study effects of habituation of the velocity storage time constant in the vestibular system on motion sickness. Twenty-nine subjects, eleven of whom were susceptible to motion sickness from common transportation, were ..
  2. Ji J, So R, Cheung R. Isolating the effects of vection and optokinetic nystagmus on optokinetic rotation-induced motion sickness. Hum Factors. 2009;51:739-51 pubmed
    This study investigates isolated effects of vection and optokinetic nystagmus (OKN) on visually induced motion sickness (VIMS) provoked by rotating optokinetic drum patterns.
  3. Moeller L, Lempert T. Mal de debarquement: pseudo-hallucinations from vestibular memory?. J Neurol. 2007;254:813-5 pubmed
  4. Evans R, Marcus D, Furman J. Motion sickness and migraine. Headache. 2007;47:607-10 pubmed
  5. Bonnet C, Faugloire E, Riley M, Bardy B, Stoffregen T. Motion sickness preceded by unstable displacements of the center of pressure. Hum Mov Sci. 2006;25:800-20 pubmed
    We exposed standing participants to optic flow in a moving room. Motion sickness was induced by motion that simulated the amplitude and frequency of standing sway...
  6. Caillet G, Bosser G, Gauchard G, Chau N, Benamghar L, Perrin P. Effect of sporting activity practice on susceptibility to motion sickness. Brain Res Bull. 2006;69:288-93 pubmed
    The theory of visuo-vestibular conflict is the most commonly accepted to explain motion sickness. Visual, vestibular and proprioceptive afferences are involved in balance control and this function can be improved by physical and sporting ..
  7. Lien H, Sun W, Chen Y, Kim H, Hasler W, Owyang C. Effects of ginger on motion sickness and gastric slow-wave dysrhythmias induced by circular vection. Am J Physiol Gastrointest Liver Physiol. 2003;284:G481-9 pubmed
    Ginger has long been used as an alternative medication to prevent motion sickness. The mechanism of its action, however, is unknown...
  8. Yokota Y, Aoki M, Mizuta K, Ito Y, Isu N. Motion sickness susceptibility associated with visually induced postural instability and cardiac autonomic responses in healthy subjects. Acta Otolaryngol. 2005;125:280-5 pubmed
    ..the hypothesis that postural sway and autonomic responses to moving visual stimuli may be associated with motion sickness susceptibility...
  9. Gupta Y, Chaudhary G. Effect of antiemetic drugs on decrease in gastric emptying in experimental model of motion sickness in rats. Acta Pharmacol Sin. 2003;24:296-300 pubmed
    To study the effect of pretreatment with different antiemetic drugs on the motion sickness-induced inhibition in gastric emptying.
  10. Chen Y, Duann J, Chuang S, Lin C, Ko L, Jung T, et al. Spatial and temporal EEG dynamics of motion sickness. Neuroimage. 2010;49:2862-70 pubmed publisher
    ..motion platform with six degrees of freedom, which provides both visual and vestibular stimulations to induce motion sickness in a manner that is close to that in daily life...
  11. Dai M, Kunin M, Raphan T, Cohen B. The relation of motion sickness to the spatial-temporal properties of velocity storage. Exp Brain Res. 2003;151:173-89 pubmed
    ..With recurrent exposure, subjects habituate and can make more head movements before experiencing overpowering motion sickness. We questioned whether promethazine lessened the vertigo or delayed the habituation, whether habituation of ..
  12. Perrin P, Lion A, Bosser G, Gauchard G, Meistelman C. Motion sickness in rally car co-drivers. Aviat Space Environ Med. 2013;84:473-7 pubmed
    ..This study aimed to evaluate predictors of motion sickness (MS) in rally car co-drivers exposed to various accelerations.
  13. Stoffregen T, Faugloire E, Yoshida K, Flanagan M, Merhi O. Motion sickness and postural sway in console video games. Hum Factors. 2008;50:322-31 pubmed
    We tested the hypotheses that (a) participants might develop motion sickness while playing "off-the-shelf" console video games and (b) postural motion would differ between sick and well participants, prior to the onset of ..
  14. Villard S, Flanagan M, Albanese G, Stoffregen T. Postural instability and motion sickness in a virtual moving room. Hum Factors. 2008;50:332-45 pubmed
    We examined motion sickness in an oscillating virtual environment presented via a video projector system.
  15. Harm D, Schlegel T. Predicting motion sickness during parabolic flight. Auton Neurosci. 2002;97:116-21 pubmed
    There are large individual differences in susceptibility to motion sickness. Attempts to predict who will become motion sick have had limited success...
  16. Dong X, Yoshida K, Stoffregen T. Control of a virtual vehicle influences postural activity and motion sickness. J Exp Psychol Appl. 2011;17:128-38 pubmed publisher
    Everyday experience suggests that drivers are less susceptible to motion sickness than passengers. In the context of inertial motion (i.e...
  17. Flanagan M, May J, Dobie T. The role of vection, eye movements and postural instability in the etiology of motion sickness. J Vestib Res. 2004;14:335-46 pubmed
    b>Motion sickness is a term that is commonly used to describe the ill effects of many provocative motion (e.g. seagoing or air travel) and apparent motion (e.g...
  18. Williamson M, Thomas M, Stern R. The contribution of expectations to motion sickness symptoms and gastric activity. J Psychosom Res. 2004;56:721-6 pubmed
    ..investigation was to determine in healthy adults the effect of expectation manipulations on the development of motion sickness, as indicated by abnormal gastric myoelectric activity and subjective reports of symptoms of motion sickness.
  19. Thornton W, Bonato F. Space motion sickness and motion sickness: symptoms and etiology. Aviat Space Environ Med. 2013;84:716-21 pubmed
    The adverse symptoms of space motion sickness (SMS) have remained problematic since the beginning of manned spaceflight...
  20. Nachum Z, Shupak A, Letichevsky V, Ben David J, Tal D, Tamir A, et al. Mal de debarquement and posture: reduced reliance on vestibular and visual cues. Laryngoscope. 2004;114:581-6 pubmed
    The neural mismatch theory assumes that the intersensory conflicts leading to motion sickness are resolved by changes in the relative weighting of the various senses that contribute to orientation...
  21. Zajonc T, Roland P. Vertigo and motion sickness. Part II: Pharmacologic treatment. Ear Nose Throat J. 2006;85:25-35 pubmed
    ..Vertigo is similar to motion sickness in that both may be caused by vestibular stimulation that does not match an internal model of expected ..
  22. Furman J, Marcus D. A pilot study of rizatriptan and visually-induced motion sickness in migraineurs. Int J Med Sci. 2009;6:212-7 pubmed
    Limited evidence suggests that rizatriptan given before vestibular stimulation reduces motion sickness in persons with migraine-related dizziness...
  23. Lempert T, Neuhauser H. Epidemiology of vertigo, migraine and vestibular migraine. J Neurol. 2009;256:333-8 pubmed publisher
    ..frequently in migraineurs than in controls including benign paroxysmal positional vertigo, Meniere's disease, motion sickness, cerebellar disorders and anxiety syndromes which may present with dizziness...
  24. Cohen B, Dai M, Yakushin S, Raphan T. Baclofen, motion sickness susceptibility and the neural basis for velocity storage. Prog Brain Res. 2008;171:543-53 pubmed publisher
    ..T(VOR)) of the angular vestibulo-ocular reflex (aVOR) by habituation is associated with a decrease in motion sickness susceptibility...
  25. Griffin M, Newman M. Visual field effects on motion sickness in cars. Aviat Space Environ Med. 2004;75:739-48 pubmed
    It is commonly assumed that car passengers who suffer from motion sickness will benefit from being able to see the road ahead.
  26. Kennedy R, Drexler J, Kennedy R. Research in visually induced motion sickness. Appl Ergon. 2010;41:494-503 pubmed publisher
    While humans have experienced motion sickness symptoms in response to inertial motion from early history through the present day, motion sickness symptoms also occur from exposure to some types of visual displays...
  27. Nobel G, Eiken O, Tribukait A, Kolegard R, Mekjavic I. Motion sickness increases the risk of accidental hypothermia. Eur J Appl Physiol. 2006;98:48-55 pubmed
    b>Motion sickness (MS) has been found to increase body-core cooling during immersion in 28 degrees C water, an effect ascribed to attenuation of the cold-induced peripheral vasoconstriction (Mekjavic et al...
  28. Akiduki H, Nishiike S, Watanabe H, Matsuoka K, Kubo T, Takeda N. Visual-vestibular conflict induced by virtual reality in humans. Neurosci Lett. 2003;340:197-200 pubmed
    Conflicting inputs from visual and vestibular afferents produce motion sickness and postural instability. However, the relationship of visual and vestibular inputs to each other remains obscure...
  29. Solimini A, Mannocci A, Di Thiene D, La Torre G. A survey of visually induced symptoms and associated factors in spectators of three dimensional stereoscopic movies. BMC Public Health. 2012;12:779 pubmed publisher
    ..This study aims to (1) quantify the occurrence of visually induced symptoms suffered by the spectators during and after viewing a commercial 3D movie and (2) to assess individual and environmental factors associated to those symptoms...
  30. Dai M, Raphan T, Cohen B. Labyrinthine lesions and motion sickness susceptibility. Exp Brain Res. 2007;178:477-87 pubmed
    ..We have proposed that motion sickness is generated through velocity storage, when its orientation vector, which lies close to the gravitational ..
  31. Simmons R, Phillips J, Lojewski R, Wang Z, Boyd J, Putcha L. The efficacy of low-dose intranasal scopolamine for motion sickness. Aviat Space Environ Med. 2010;81:405-12 pubmed
    Scopolamine is an effective motion sickness prophylactic, but oral and transdermal formulations are slowly absorbed. To enhance absorption and potentially efficacy, an intranasal formulation of scopolamine (INSCOP) was tested.
  32. Chouker A, Kaufmann I, Kreth S, Hauer D, Feuerecker M, Thieme D, et al. Motion sickness, stress and the endocannabinoid system. PLoS ONE. 2010;5:e10752 pubmed publisher
    A substantial number of individuals are at risk for the development of motion sickness induced nausea and vomiting (N&V) during road, air or sea travel...
  33. Cai Y, Wang J, Chen X, Li H, Li M, Guo J. Decreased Fos protein expression in rat caudal vestibular nucleus is associated with motion sickness habituation. Neurosci Lett. 2010;480:87-91 pubmed publisher
    ..These results suggest that the change of neuronal plasticity in the caudal vestibular nucleus might contribute to attenuation of gastrointestinal symptoms during motion sickness habituation process.
  34. Tanguy S, Quarck G, Etard O, Gauthier A, Denise P. Vestibulo-ocular reflex and motion sickness in figure skaters. Eur J Appl Physiol. 2008;104:1031-7 pubmed publisher
    ..on the functional plasticity of the vestibular system, we quantified vestibulo-ocular reflex (VOR) and motion sickness (MS) intensity in 11 female figure skaters and 11 matched control subjects...
  35. Chang C, Pan W, Tseng L, Stoffregen T. Postural activity and motion sickness during video game play in children and adults. Exp Brain Res. 2012;217:299-309 pubmed publisher
    Research has confirmed that console video games give rise to motion sickness in many adults...
  36. Yu X, Cai G, Liu A, Chu Z, Su D. A novel animal model for motion sickness and its first application in rodents. Physiol Behav. 2007;92:702-7 pubmed
    The present work was designed to establish a novel animal model for motion sickness (MS) in rodents and to evaluate the effects of a combination of scopolamine and modafinil on MS with this novel method...
  37. Marcus D, Furman J, Balaban C. Motion sickness in migraine sufferers. Expert Opin Pharmacother. 2005;6:2691-7 pubmed
    b>Motion sickness commonly occurs after exposure to actual motion, such as car or amusement park rides, or virtual motion, such as panoramic movies...
  38. Merhi O, Faugloire E, Flanagan M, Stoffregen T. Motion sickness, console video games, and head-mounted displays. Hum Factors. 2007;49:920-34 pubmed
    ..We evaluated the nauseogenic properties of commercial console video games (i.e., games that are sold to the public) when presented through a head-mounted display...
  39. Muth E, Elkins A. High dose ondansetron for reducing motion sickness in highly susceptible subjects. Aviat Space Environ Med. 2007;78:686-92 pubmed
    Ondansetron is currently being explored as a treatment for motion sickness due to its proven prophylactic effect on post-operative nausea, the nausea and vomiting associated with chemotherapy, and its lack of side effects...
  40. Nobel G, Tribukait A, Mekjavic I, Eiken O. Effects of motion sickness on thermoregulatory responses in a thermoneutral air environment. Eur J Appl Physiol. 2012;112:1717-23 pubmed publisher
    b>Motion sickness (MS) has been identified as a non-thermal factor that can moderate autonomic thermoregulatory responses...
  41. Otto B, Riepl R, Klosterhalfen S, Enck P. Endocrine correlates of acute nausea and vomiting. Auton Neurosci. 2006;129:17-21 pubmed
    ..fully understood, but it has been shown that different stress hormones are released into circulation during motion sickness. Studies with animals and humans have shown that acute nausea activates the hypothalamo-pituitary-adrenal ..
  42. Ohyama S, Nishiike S, Watanabe H, Matsuoka K, Akizuki H, Takeda N, et al. Autonomic responses during motion sickness induced by virtual reality. Auris Nasus Larynx. 2007;34:303-6 pubmed
    To examine the development of subjective symptoms and heart rate variability (HRV) during motion sickness induced by virtual reality (VR).
  43. Keshavarz B, Hecht H. Validating an efficient method to quantify motion sickness. Hum Factors. 2011;53:415-26 pubmed
    b>Motion sickness (MS) can be a debilitating side effect associated with motion in real or virtual environments. We analyzed the effect of expectancy on MS and propose and validate a fast and simple MS measure.
  44. Seibel K, Schaffler K, Reitmeir P, Golly I. A randomised, placebo-controlled study comparing two formulations of dimenhydrinate with respect to efficacy in motion sickness and sedation. Arzneimittelforschung. 2002;52:529-36 pubmed
    ..fast release tablet with three chewing gums (divided dose principle), with regard to their efficacy in a motion sickness model and their detrimental effect on vigilance and central nervous system (CNS) performance...
  45. Reavley C, Golding J, Cherkas L, Spector T, MacGregor A. Genetic influences on motion sickness susceptibility in adult women: a classical twin study. Aviat Space Environ Med. 2006;77:1148-52 pubmed
    b>Motion sickness is a common and potentially debilitating condition that characteristically occurs in situations of conflicting sensory input...
  46. Cohen B, Dai M, Raphan T. The critical role of velocity storage in production of motion sickness. Ann N Y Acad Sci. 2003;1004:359-76 pubmed
    We propose that motion sickness is mediated through the orientation properties of velocity storage in the vestibular system that tend to align eye velocity produced by the angular vestibulo-ocular reflex (aVOR) with gravito-inertial ..
  47. Dai M, Sofroniou S, Kunin M, Raphan T, Cohen B. Motion sickness induced by off-vertical axis rotation (OVAR). Exp Brain Res. 2010;204:207-22 pubmed publisher
    We tested the hypothesis that motion sickness is produced by an integration of the disparity between eye velocity and the yaw-axis orientation vector of velocity storage...
  48. Jeong S, Oh S, Kim H, Koo J, Kim J. Vestibular dysfunction in migraine: effects of associated vertigo and motion sickness. J Neurol. 2010;257:905-12 pubmed publisher
    The mechanisms of vestibular migraine and motion sickness remain unknown...
  49. Drummond P. Effect of tryptophan depletion on symptoms of motion sickness in migraineurs. Neurology. 2005;65:620-2 pubmed
    ..an amino acid drink that contained or omitted l-tryptophan (thereby reducing brain serotonin synthesis), motion sickness was provoked by the visual illusion of movement...
  50. Bos J, Bles W. Motion sickness induced by optokinetic drums. Aviat Space Environ Med. 2004;75:172-4 pubmed
    b>Motion sickness is not only elicited by certain kinds of self-motion, but also by motion of a visual scene. In case of the latter, optokinetic drums are often used and a visual-vestibular conflict is assumed to cause the sickness...
  51. Cheung B, Hofer K. Lack of gender difference in motion sickness induced by vestibular Coriolis cross-coupling. J Vestib Res. 2002;12:191-200 pubmed
    It has been reported that females are more susceptible to motion sickness than males. Supporting evidence is primarily based on retrospective survey questionnaires and self-reporting...
  52. Bronstein A, Golding J, Gresty M. Vertigo and dizziness from environmental motion: visual vertigo, motion sickness, and drivers' disorientation. Semin Neurol. 2013;33:219-30 pubmed publisher
    ..Common environmental motion conditions include visual vertigo, motion sickness, and motorists' disorientation...
  53. Cha Y, Brodsky J, Ishiyama G, Sabatti C, Baloh R. Clinical features and associated syndromes of mal de debarquement. J Neurol. 2008;255:1038-44 pubmed publisher
    ..To investigate the clinical features and natural history of mal de debarquement (MdD)...