mobility limitation


Summary: Difficulty in walking from place to place.

Top Publications

  1. Welmer A, Angleman S, Rydwik E, Fratiglioni L, Qiu C. Association of cardiovascular burden with mobility limitation among elderly people: a population-based study. PLoS ONE. 2013;8:e65815 pubmed publisher what extent individual and aggregated CRFs and cardiovascular diseases (CVDs) are associated with mobility limitation. The study sample included 2725 participants (age ?60 years, mean age 72...
  2. Brown C, Flood K. Mobility limitation in the older patient: a clinical review. JAMA. 2013;310:1168-77 pubmed publisher
    ..Search of PubMed and PEDro from January 1985 to March 31, 2013, using the search terms mobility limitation, walking difficulty, and ambulatory difficulty to identify English-language, peer-reviewed systematic ..
  3. Alley D, Shardell M, Peters K, McLean R, Dam T, Kenny A, et al. Grip strength cutpoints for the identification of clinically relevant weakness. J Gerontol A Biol Sci Med Sci. 2014;69:559-66 pubmed publisher
    ..8 m/s...
  4. McLean R, Shardell M, Alley D, Cawthon P, Fragala M, Harris T, et al. Criteria for clinically relevant weakness and low lean mass and their longitudinal association with incident mobility impairment and mortality: the foundation for the National Institutes of Health (FNIH) sarcopenia project. J Gerontol A Biol Sci Med Sci. 2014;69:576-83 pubmed publisher
    ..8 m/s) and mortality. Providing validity for these criteria is essential for research and clinical evaluation...
  5. Fairhall N, Sherrington C, Kurrle S, Lord S, Lockwood K, Cameron I. Effect of a multifactorial interdisciplinary intervention on mobility-related disability in frail older people: randomised controlled trial. BMC Med. 2012;10:120 pubmed publisher
    ..The benefit was evident at both the participation and activity levels of mobility-related disability. Australia and New Zealand Clinical Trials Register (ANZCTR): ANZCTRN12608000507381. ..
  6. Kim M, Yabushita N, Tanaka K. Exploring effective items of physical function in slow walking speed and self-reported mobility limitation in community-dwelling older adults. Geriatr Gerontol Int. 2012;12:50-8 pubmed publisher
    ..explore the items that affect each physical function task by comparing slow walking speed and self-reported mobility limitation in community-dwelling older adults...
  7. Morley J, Abbatecola A, Argiles J, Baracos V, Bauer J, Bhasin S, et al. Sarcopenia with limited mobility: an international consensus. J Am Med Dir Assoc. 2011;12:403-9 pubmed publisher
    ..Clinically significant interventions are defined as an increase in the 6-minute walk of at least 50 meters or an increase of walking speed of at least 0.1 m/s. ..
  8. Hicks G, Shardell M, Alley D, Miller R, Bandinelli S, Guralnik J, et al. Absolute strength and loss of strength as predictors of mobility decline in older adults: the InCHIANTI study. J Gerontol A Biol Sci Med Sci. 2012;67:66-73 pubmed publisher
    ..Findings suggest that strength and power measured at one time point are more predictive of mobility decline than 3-year changes and that low strength and power are particularly powerful risk factors in men. ..
  9. Kim M, Seino S, Kim M, Yabushita N, Okura T, Okuno J, et al. Validation of lower extremity performance tests for determining the mobility limitation levels in community-dwelling older women. Aging Clin Exp Res. 2009;21:437-44 pubmed
    ..cut-off values for eight lower extremity performance (LEP) tests in community-dwelling older women with mobility limitation (ML) levels. The ML levels of 433 community-dwelling older women, mean age 73.2 years (SD 5...

More Information


  1. Manini T, Newman A, Fielding R, Blair S, Perri M, Anton S, et al. Effects of exercise on mobility in obese and nonobese older adults. Obesity (Silver Spring). 2010;18:1168-75 pubmed publisher
    ..5%; SA: +2.5%) and nonobese older adults (PA: +18.6%; SA: +6.1%). A moderate intensity PA intervention improves physical function in older adults, but the positive benefits are attenuated with obesity. ..
  2. Abellan Van Kan G, Rolland Y, Andrieu S, Bauer J, Beauchet O, Bonnefoy M, et al. Gait speed at usual pace as a predictor of adverse outcomes in community-dwelling older people an International Academy on Nutrition and Aging (IANA) Task Force. J Nutr Health Aging. 2009;13:881-9 pubmed
    ..The assessment at usual pace over 4 meters was the most often used method in literature and might represent a quick, safe, inexpensive and highly reliable instrument to be implemented. ..
  3. Houston D, Neiberg R, Tooze J, Hausman D, Johnson M, Cauley J, et al. Low 25-hydroxyvitamin D predicts the onset of mobility limitation and disability in community-dwelling older adults: the Health ABC Study. J Gerontol A Biol Sci Med Sci. 2013;68:181-7 pubmed publisher
    ..We examined the association between 25(OH)D, parathyroid hormone (PTH), and the onset of mobility limitation and disability over 6 years of follow-up in community-dwelling, initially well-functioning older adults ..
  4. Conway J, Tomkins C, Haig A. Walking assessment in people with lumbar spinal stenosis: capacity, performance, and self-report measures. Spine J. 2011;11:816-23 pubmed publisher
    ..Survey instruments appear to reflect capacity rather than performance. This dissociation between walking capacity and walking performance has implications for the clinical management and outcomes assessment of people with LSS. ..
  5. Rejeski W, Brubaker P, Goff D, Bearon L, McClelland J, Perri M, et al. Translating weight loss and physical activity programs into the community to preserve mobility in older, obese adults in poor cardiovascular health. Arch Intern Med. 2011;171:880-6 pubmed publisher Identifier: NCT00119795. ..
  6. Satariano W, Guralnik J, Jackson R, Marottoli R, Phelan E, Prohaska T. Mobility and aging: new directions for public health action. Am J Public Health. 2012;102:1508-15 pubmed publisher
    ..New strategies for research, practice, and policy are needed to move beyond categorical promotion programs in walking and driving to establish a comprehensive program to enhance safe mobility in all its forms. ..
  7. Mechakra Tahiri S, Freeman E, Haddad S, Samson E, Zunzunegui M. The gender gap in mobility: a global cross-sectional study. BMC Public Health. 2012;12:598 pubmed publisher
    ..Differences in chronic diseases are the main reasons for this gender gap. The gender gap seems to be greater in regions with the largest loss of human development due to gender inequality. ..
  8. Keeler E, Guralnik J, Tian H, Wallace R, Reuben D. The impact of functional status on life expectancy in older persons. J Gerontol A Biol Sci Med Sci. 2010;65:727-33 pubmed publisher
    ..Both ADL and mobility disability result in diminished survival and more of that survival period spent in disabled states. ..
  9. Gray S, Boudreau R, Newman A, Studenski S, Shorr R, Bauer D, et al. Angiotensin-converting enzyme inhibitor and statin use and incident mobility limitation in community-dwelling older adults: the Health, Aging and Body Composition study. J Am Geriatr Soc. 2011;59:2226-32 pubmed publisher
    ..of angiotensin-converting enzyme (ACE) inhibitors and statins is associated with a lower risk of incident mobility limitation in older community dwelling adults. Longitudinal cohort study...
  10. Herman T, Giladi N, Hausdorff J. Properties of the 'timed up and go' test: more than meets the eye. Gerontology. 2011;57:203-10 pubmed publisher
    ..Perhaps the transferring and turning components of the TUG help to convert this relatively simple motor task into a more complex measure that also depends on cognitive resources. ..
  11. Buchman A, Boyle P, Leurgans S, Barnes L, Bennett D. Cognitive function is associated with the development of mobility impairments in community-dwelling elders. Am J Geriatr Psychiatry. 2011;19:571-80 pubmed publisher
    ..Linear mixed-effects models showed that global cognition at baseline was associated with the rate of declining mobility. Among ambulatory elders, cognition is associated with incident mobility impairment and mobility decline. ..
  12. Krasnoff J, Basaria S, Pencina M, Jasuja G, Vasan R, Ulloor J, et al. Free testosterone levels are associated with mobility limitation and physical performance in community-dwelling men: the Framingham Offspring Study. J Clin Endocrinol Metab. 2010;95:2790-9 pubmed publisher
    b>Mobility limitation is associated with increased morbidity and mortality. The relationship between circulating testosterone and mobility limitation and physical performance is incompletely understood...
  13. Hardy S, Kang Y, Studenski S, Degenholtz H. Ability to walk 1/4 mile predicts subsequent disability, mortality, and health care costs. J Gen Intern Med. 2011;26:130-5 pubmed publisher
    ..Mobility disability may be used to target high-risk patients for care management and preventive interventions. ..
  14. Sallinen J, Stenholm S, Rantanen T, Heliövaara M, Sainio P, Koskinen S. Hand-grip strength cut points to screen older persons at risk for mobility limitation. J Am Geriatr Soc. 2010;58:1721-6 pubmed publisher
    To determine optimal hand-grip strength cut points for likelihood of mobility limitation in older people and to study whether these cut points differ according to body mass index (BMI). Cross-sectional analysis of data...
  15. Stenholm S, Koster A, Alley D, Houston D, Kanaya A, Lee J, et al. Joint association of obesity and metabolic syndrome with incident mobility limitation in older men and women--results from the Health, Aging, and Body Composition Study. J Gerontol A Biol Sci Med Sci. 2010;65:84-92 pubmed publisher physical function, the joint association of obesity and metabolic alterations with risk of incident mobility limitation is unknown...
  16. Stenholm S, Kronholm E, Sainio P, Borodulin K, Era P, Fogelholm M, et al. Sleep-related factors and mobility in older men and women. J Gerontol A Biol Sci Med Sci. 2010;65:649-57 pubmed publisher
    ..Maximal walking speed was measured, and mobility limitation was defined as self-reported difficulties in walking 500 m or stair climbing...
  17. Basaria S, Davda M, Travison T, Ulloor J, Singh R, Bhasin S. Risk factors associated with cardiovascular events during testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci. 2013;68:153-60 pubmed publisher
    ..Men aged 65 years or more, with mobility limitation, total testosterone 100-350 ng/dL, or free testosterone less than 50 pg/mL, were randomized to placebo or ..
  18. Miszkurka M, Zunzunegui M, Langlois E, Freeman E, Kouanda S, Haddad S. Gender differences in mobility disability during young, middle and older age in West African adults. Glob Public Health. 2012;7:495-508 pubmed publisher
    ..94 (95%CI 0.70; 1.25), 2.19 (95%CI 1.61; 2.96) and 1.90 (95%CI 1.27; 2.84). These results constitute a benchmark for the study of trends of mobility disability in West Africa and could be used by policy planners. ..
  19. Travison T, Basaria S, Storer T, Jette A, Miciek R, Farwell W, et al. Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci. 2011;66:1090-9 pubmed publisher
    ..Trial determined the effects of testosterone on muscle performance and physical function in older men with mobility limitation. Trial's Data and Safety Monitoring Board recommended enrollment cessation due to increased frequency of ..
  20. Hutchings L, Fox R, Chesser T. Proximal femoral fractures in the elderly: how are we measuring outcome?. Injury. 2011;42:1205-13 pubmed publisher
    ..We would recommend the validation of commonly used scales for this population, and would advise the use of scales from more than one category to assess outcome. ..
  21. Fairhall N, Sherrington C, Kurrle S, Lord S, Cameron I. ICF participation restriction is common in frail, community-dwelling older people: an observational cross-sectional study. Physiotherapy. 2011;97:26-32 pubmed publisher
    ..It was associated with factors from multiple levels of the International Classification of Functioning, Disability and Health. Further research is suggested to investigate the causes and treatment of participation restriction. ..
  22. Ballemans J, Kempen G, Zijlstra G. Orientation and mobility training for partially-sighted older adults using an identification cane: a systematic review. Clin Rehabil. 2011;25:880-91 pubmed publisher
    ..Our review of the literature showed a lack of well-described protocols and studies on orientation and mobility training in identification cane use. ..
  23. Valtonen A, Pöyhönen T, Sipila S, Heinonen A. Effects of aquatic resistance training on mobility limitation and lower-limb impairments after knee replacement. Arch Phys Med Rehabil. 2010;91:833-9 pubmed publisher
    ..Twelve-week progressive aquatic resistance training (n=26) or no intervention (n=24). Mobility limitation assessed by walking speed and stair ascending time, and self-reported physical functional difficulty, pain, ..
  24. Yount K, Hoddinott J, Stein A. Disability and self-rated health among older women and men in rural Guatemala: the role of obesity and chronic conditions. Soc Sci Med. 2010;71:1418-27 pubmed publisher
    ..Such interventions also may reduce gender gaps in later-life disability and self-rated health. ..
  25. Slaughter S, Eliasziw M, Morgan D, Drummond N. Incidence and predictors of excess disability in walking among nursing home residents with middle-stage dementia: a prospective cohort study. Int Psychogeriatr. 2011;23:54-64 pubmed publisher
    ..Creating supportive environments, ensuring access to cognitive enhancer drugs, and preventing and treating depression and the adverse effects of antidepressants, may help to reduce walking disability and excess disability. ..
  26. Clarke P, Smith J. Aging in a cultural context: cross-national differences in disability and the moderating role of personal control among older adults in the United States and England. J Gerontol B Psychol Sci Soc Sci. 2011;66:457-67 pubmed publisher
    ..This paper highlights the role of culture in shaping health across adults aging in different sociopolitical contexts. ..
  27. Iannessi A, Amoretti N, Marcy P, Sedat J. Percutaneous cementoplasty for the treatment of extraspinal painful bone lesion, a prospective study. Diagn Interv Imaging. 2012;93:859-70 pubmed publisher
    ..We prospectively followed 20 patients who received a percutaneous cementoplasty on painful lytic bone lesions between May 2008 and May 2010...
  28. Vicente V, Ekebergh M, Castren M, Sjostrand F, Svensson L, Sundström B. Differentiating frailty in older people using the Swedish ambulance service: a retrospective audit. Int Emerg Nurs. 2012;20:228-35 pubmed publisher
    ..Furthermore, the concept of frailty ought to be included in "The International Statistical Classification of Diseases and Related Health Problems" (ICD-10). ..
  29. Fragala M, Clark M, Walsh S, Kleppinger A, Judge J, Kuchel G, et al. Gender differences in anthropometric predictors of physical performance in older adults. Gend Med. 2012;9:445-56 pubmed publisher
    ..Results implicate the prioritized importance of healthy weight and muscle maintenance in older women and men for maintained physical functioning with aging. ..
  30. Lagergren M, Johnell K, Schön P, Danielsson M. Towards a postponement of activities of daily living dependence and mobility limitations: Trends in healthy life years in old age in Sweden. Scand J Public Health. 2017;45:520-527 pubmed publisher
    ..Thus the years with ADL dependence and mobility limitations are postponed to a higher age and the numbers of these years have decreased. ..
  31. Groffen D, Koster A, Bosma H, Van den Akker M, Aspelund T, Siggeirsdottir K, et al. Socioeconomic factors from midlife predict mobility limitation and depressed mood three decades later; findings from the AGES-Reykjavik Study. BMC Public Health. 2013;13:101 pubmed publisher
    ..The present study aims to examine the effect of midlife socioeconomic factors on mobility limitation and depressed mood three decades later...
  32. Silva A, Alvarelhão J, Queirós A, Rocha N. Pain intensity is associated with self-reported disability for several domains of life in a sample of patients with musculoskeletal pain aged 50 or more. Disabil Health J. 2013;6:369-76 pubmed publisher
    ..001) and total score (adjusted R(2) = 0.19, p < 0.001). Pain intensity seems to be an important predictor of disability for several domains of life, suggesting that pain-related disability should be assessed for these domains. ..
  33. Krist L, Dimeo F, Keil T. Can progressive resistance training twice a week improve mobility, muscle strength, and quality of life in very elderly nursing-home residents with impaired mobility? A pilot study. Clin Interv Aging. 2013;8:443-8 pubmed publisher
    ..Resistance training twice a week over 2 months seemed to considerably improve mobility and muscle strength in persons aged 77-97 years with impaired mobility. ..
  34. Artaud F, Dugravot A, Sabia S, Singh Manoux A, Tzourio C, Elbaz A. Unhealthy behaviours and disability in older adults: three-City Dijon cohort study. BMJ. 2013;347:f4240 pubmed publisher
    ..Chronic conditions, depressive symptoms, trauma, and body mass index partially explained this association. ..
  35. Bishop N, Eggum Wilkens N, Haas S, Kronenfeld J. Estimating the Co-Development of Cognitive Decline and Physical Mobility Limitations in Older U.S. Adults. Demography. 2016;53:337-64 pubmed publisher
    ..Demographic and socioeconomic characteristics were consistently associated with initial cognitive and physical health but had few relations with change in these measures. ..
  36. Gray Miceli D. Impaired Mobility and Functional Decline in Older Adults: Evidence to Facilitate a Practice Change. Nurs Clin North Am. 2017;52:469-487 pubmed publisher
  37. Kim J, Han Z, Song D, Oh H, Chung M. Characteristics of dysphagia in children with cerebral palsy, related to gross motor function. Am J Phys Med Rehabil. 2013;92:912-9 pubmed publisher
    ..Therefore, the authors suggest that early dysphagia evaluation including videofluoroscopic swallow study is necessary in managing feeding problems and may prevent chronic aspiration, malnutrition, and infections. ..
  38. Hignett S, Sands G, Fray M, Xanthopoulou P, Healey F, Griffiths P. Which bed designs and patient characteristics increase bed rail use?. Age Ageing. 2013;42:531-5 pubmed publisher
    ..there were indications that rails were being used inappropriately (as a restraint) for both confused patients and those needing assistance to mobilise. ..
  39. Bar Haim S, Al Jarrah M, Nammourah I, Harries N. Mechanical efficiency and balance in adolescents and young adults with cerebral palsy. Gait Posture. 2013;38:668-73 pubmed publisher
    ..Effective therapy to improve walking in younger children might incorporate more balance-focused exercises, similar to those related to BBS items strongly associated with ME. ..
  40. Hart T, Ferraro M, Myers R, Ellis C. Opening the black box: lessons learned from an interdisciplinary inquiry into the learning-based contents of brain injury rehabilitation. Arch Phys Med Rehabil. 2014;95:S66-73 pubmed publisher
    ..The focus on individual therapy sessions allowed for rich qualitative detail, but a less granular analysis will be necessary for comprehensive efforts to characterize the contents of therapy. ..
  41. Shahid M, Saunders T, Jeys L, Grimer R. The outcome of surgical treatment for peri-acetabular metastases. Bone Joint J. 2014;96-B:132-6 pubmed publisher
    ..We recommend the 'ice-cream cone' for pelvic discontinuity and Harrington rod reconstruction for severe bone loss. Smaller defects can be safely managed using standard revision hip techniques. ..
  42. Sakakibara B, Miller W, Routhier F, Backman C, Eng J. Association between self-efficacy and participation in community-dwelling manual wheelchair users aged 50 years or older. Phys Ther. 2014;94:664-74 pubmed publisher
    ..Self-efficacy directly and indirectly influences the participation frequency in community-dwelling manual wheelchair users aged 50 years or older. Development of interventions to address low self-efficacy is warranted. ..
  43. Fieo R, Mortensen E, Rantanen T, Avlund K. Improving a measure of mobility-related fatigue (the mobility-tiredness scale) by establishing item intensity. J Am Geriatr Soc. 2013;61:429-33 pubmed publisher
  44. Davenport R, Mann W, LUTZ B. How older adults make decisions regarding smart technology: an ethnographic approach. Assist Technol. 2012;24:168-81; quiz 182-3 pubmed
    ..Future designers could use this decision model to create appropriately matched technological devices to promote independence of aging baby boomers with mobility impairments. ..
  45. Manini T, Anton S, Beavers D, Cauley J, Espeland M, Fielding R, et al. ENabling Reduction of Low-grade Inflammation in SEniors Pilot Study: Concept, Rationale, and Design. J Am Geriatr Soc. 2017;65:1961-1968 pubmed publisher
  46. Pokhabov D, Abramov V, Pokhabov D. [Possibilities of non-drug treatment for Parkinson's disease]. Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116:22-29 pubmed publisher
  47. Pedersen M, Petersen J, Beyer N, Damkjær L, Bandholm T. Supervised progressive cross-continuum strength training compared with usual care in older medical patients: study protocol for a randomized controlled trial (the STAND-Cph trial). Trials. 2016;17:176 pubmed publisher
    ..e. two well-performed strength training exercises combined with protein supplementation, to facilitate implementation in a busy clinical care setting, given a positive trial outcome. NCT01964482 . ..
  48. Kara M, Tiftik T, Oken O, Akkaya N, Tunc H, Ozcakar L. Ultrasonographic measurement of femoral cartilage thickness in patients with spinal cord injury. J Rehabil Med. 2013;45:145-8 pubmed publisher
    ..Future studies including histological evaluations may elucidate whether such changes are favourable for the knee joints of patients with spinal cord injury. ..
  49. Febrer A, Vigo M, Rodriguez N, Medina J, Colomer J, Nascimento A. [Fractures in spinal muscular atrophy]. Rev Neurol. 2013;57:207-11 pubmed
    ..To determine the frequency of fractures in patients with spinal muscular atrophy, their mechanism of production, age at appearance and functional repercussions...
  50. McDonough C, Jette A, Ni P, Bogusz K, Marfeo E, Brandt D, et al. Development of a self-report physical function instrument for disability assessment: item pool construction and factor analysis. Arch Phys Med Rehabil. 2013;94:1653-60 pubmed publisher
    ..The 4 scales relevant to work activities offer promise for providing reliable information about claimant physical functioning relevant to work disability. ..
  51. Hammel J, Southall K, Jutai J, Finlayson M, Kashindi G, Fok D. Evaluating use and outcomes of mobility technology: a multiple stakeholder analysis. Disabil Rehabil Assist Technol. 2013;8:294-304 pubmed publisher
    ..Implications for MT assessment, service delivery, outcomes research, and interventions are discussed. ..
  52. Nael V, Pérès K, Carriere I, Daien V, Scherlen A, Arleo A, et al. Visual Impairment, Undercorrected Refractive Errors, and Activity Limitations in Older Adults: Findings From the Three-City Alienor Study. Invest Ophthalmol Vis Sci. 2017;58:2359-2365 pubmed publisher
    ..These results underline the importance of eye examinations in older adults to prevent disability. ..
  53. Liu C, Lyass A, Massaro J, D Agostino R, Fox C, Murabito J. Chronic kidney disease defined by cystatin C predicts mobility disability and changes in gait speed: the Framingham Offspring Study. J Gerontol A Biol Sci Med Sci. 2014;69:301-7 pubmed publisher
    ..07 [SE 0.02], p = .0022). CKD(cys) was associated with higher odds of incident mobility disability and greater decline in gait speed, highlighting the loss of physical independence in elders with CKD. ..