flatulence

Summary

Summary: Production or presence of gas in the gastrointestinal tract which may be expelled through the anus.

Top Publications

  1. Perez F, Accarino A, Azpiroz F, Quiroga S, Malagelada J. Gas distribution within the human gut: effect of meals. Am J Gastroenterol. 2007;102:842-9 pubmed
    ..Patients frequently complain of gas symptoms precipitated by meals, but the effect of early digestion on intestinal gas content remains unknown. Our aim was to determine the influence of meals on intestinal gas volume and distribution...
  2. Patil A, K P, Mulimani V, Veeranagouda Y, Lee K. alpha-Galactosidase from Bacillus megaterium VHM1 and its application in removal of flatulence-causing factors from soymilk. J Microbiol Biotechnol. 2010;20:1546-54 pubmed
    ..The B megaterium VHM1 enzyme treatment completely hydrolyzed flatulence-causing sugars of soymilk within one and half hour.
  3. Hernando Harder A, Serra J, Azpiroz F, Milá M, Aguade S, Malagelada C, et al. Colonic responses to gas loads in subgroups of patients with abdominal bloating. Am J Gastroenterol. 2010;105:876-82 pubmed publisher
    ..We sought to evaluate colonic gas accommodation, ileocecal competence, and colonic clearance in subgroups patients with abdominal bloating...
  4. Kurbel S, Kurbel B, Vcev A. Intestinal gases and flatulence: possible causes of occurrence. Med Hypotheses. 2006;67:235-9 pubmed
    ..Intestinal gases often accumulate and cause flatulence. This paper proposes a simple concept of intestinal gas occurrence based on our knowledge on gas resorption in ..
  5. Friis H, Bode S, Rumessen J, Gudmand Høyer E. Effect of simethicone on lactulose-induced H2 production and gastrointestinal symptoms. Digestion. 1991;49:227-30 pubmed
    ..There was no demonstrable effect of simethicone on symptoms or intestinal gas production caused by carbohydrate malabsorption...
  6. Manichanh C, Eck A, Varela E, Roca J, Clemente J, Gonzalez A, et al. Anal gas evacuation and colonic microbiota in patients with flatulence: effect of diet. Gut. 2014;63:401-8 pubmed publisher
    To characterise the influence of diet on abdominal symptoms, anal gas evacuation, intestinal gas distribution and colonic microbiota in patients complaining of flatulence.
  7. Winham D, Hutchins A. Perceptions of flatulence from bean consumption among adults in 3 feeding studies. Nutr J. 2011;10:128 pubmed publisher
    Many consumers avoid eating beans because they believe legume consumption will cause excessive intestinal gas or flatulence. An increasing body of research and the 2010 Dietary Guidelines for Americans supports the benefits of a plant-..
  8. Lebbad M, Petersson I, Karlsson L, Botero Kleiven S, Andersson J, Svenungsson B, et al. Multilocus genotyping of human Giardia isolates suggests limited zoonotic transmission and association between assemblage B and flatulence in children. PLoS Negl Trop Dis. 2011;5:e1262 pubmed publisher
    ..We tried to link different assemblages and sub-assemblages of G. intestinalis isolates from Swedish human patients to clinical symptoms and zoonotic transmission...
  9. Schmulson M, Chang L. Review article: the treatment of functional abdominal bloating and distension. Aliment Pharmacol Ther. 2011;33:1071-86 pubmed publisher
    ..Abdominal bloating and distension are common symptoms in patients with functional gastrointestinal disorders (FGIDs), however, relatively little is known about their treatment...

More Information

Publications62

  1. Ringel Kulka T, Palsson O, Maier D, Carroll I, Galanko J, Leyer G, et al. Probiotic bacteria Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07 versus placebo for the symptoms of bloating in patients with functional bowel disorders: a double-blind study. J Clin Gastroenterol. 2011;45:518-25 pubmed publisher
    ..Recent data suggest a role for the intestinal microbiota in the pathogenesis of functional bowel disorders (FBDs). Probiotic studies in FBDs generated inconsistent results suggesting a strain-specific and product-specific effect...
  2. Feng S, Saw C, Lee Y, Huang D. Novel process of fermenting black soybean [Glycine max (L.) Merrill] yogurt with dramatically reduced flatulence-causing oligosaccharides but enriched soy phytoalexins. J Agric Food Chem. 2008;56:10078-84 pubmed publisher
    ..of black soybean under fungal stress for 3 days was sufficient to reduce stachyose and raffinose (which cause flatulence) by 92 and 80%, respectively. With a pH value of 4.42, a lactic acid content of 0...
  3. Rana S, Sharma S, Sinha S, Kaur H, Sikander A, Singh K. Incidence of predominant methanogenic flora in irritable bowel syndrome patients and apparently healthy controls from North India. Dig Dis Sci. 2009;54:132-5 pubmed publisher
    b>Flatulence is a common symptom in patients with irritable bowel syndrome (IBS). This may be due to production of hydrogen by intestinal flora...
  4. Guilbert J, Flamant C, Hallalel F, Doummar D, Frata A, Renolleau S. Anti-flatulence treatment and status epilepticus: a case of camphor intoxication. Emerg Med J. 2007;24:859-60 pubmed
    ..that the nanny had given an abdominal massage to the child with an unlabelled solution reported to have anti-flatulence effects. Toxicological analysis of this solution revealed the presence of camphor...
  5. Bengtsson M, Ohlsson B, Ulander K. Development and psychometric testing of the Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS). BMC Gastroenterol. 2007;7:16 pubmed
    ..The Visual Analogue Scale for Irritable Bowel Syndrome (VAS-IBS) questionnaire was designed to measure the treatment response of symptoms and well-being in patients suffering from IBS...
  6. Di Stefano M, Miceli E, Gotti S, Missanelli A, Mazzocchi S, Corazza G. The effect of oral alpha-galactosidase on intestinal gas production and gas-related symptoms. Dig Dis Sci. 2007;52:78-83 pubmed
    Bloating, abdominal distention, and flatulence represent very frequent complaints in functional disorders but their pathophysiology and treatment are largely unknown...
  7. Quigley E. Germs, gas and the gut; the evolving role of the enteric flora in IBS. Am J Gastroenterol. 2006;101:334-5 pubmed
    ..overgrowth in some patients with IBS; the study discussed herein provides further support for this concept by describing an amelioration of bloating and flatulence following a short course of the poorly absorbed antibiotic, rifaximin.
  8. Sharara A, Aoun E, Abdul Baki H, Mounzer R, Sidani S, Elhajj I. A randomized double-blind placebo-controlled trial of rifaximin in patients with abdominal bloating and flatulence. Am J Gastroenterol. 2006;101:326-33 pubmed
    To study the efficacy of rifaximin, a nonabsorbable antibiotic, in relieving chronic functional symptoms of bloating and flatulence.
  9. Tremolaterra F, Villoria A, Azpiroz F, Serra J, Aguade S, Malagelada J. Impaired viscerosomatic reflexes and abdominal-wall dystony associated with bloating. Gastroenterology. 2006;130:1062-8 pubmed
    ..Our aim was to determine whether the abdominal wall, specifically its adaptation to intra-abdominal volumes, plays a role...
  10. Serra J, Azpiroz F, Malagelada J. Gastric distension and duodenal lipid infusion modulate intestinal gas transit and tolerance in humans. Am J Gastroenterol. 2002;97:2225-30 pubmed
    ..However, the mechanisms responsible are unknown. Our aim was to analyze the specific influence of two meal-related factors, gastric distension, and intestinal nutrients, on intestinal gas dynamics and tolerance...
  11. Salvioli B, Serra J, Azpiroz F, Lorenzo C, Aguade S, Castell J, et al. Origin of gas retention and symptoms in patients with bloating. Gastroenterology. 2005;128:574-9 pubmed
    ..Patients reporting abdominal bloating exhibit impaired tolerance to intestinal gas loads. The aim of this study was to identify the gut compartment responsible for gas retention...
  12. Ringel Y, Williams R, Kalilani L, Cook S. Prevalence, characteristics, and impact of bloating symptoms in patients with irritable bowel syndrome. Clin Gastroenterol Hepatol. 2009;7:68-72; quiz 3 pubmed publisher
    ..We investigated the prevalence, characteristics, and impact of bloating symptoms in patients with IBS...
  13. Song D, Chang S. Enzymatic degradation of oligosaccharides in pinto bean flour. J Agric Food Chem. 2006;54:1296-301 pubmed
    The use of dry edible beans is limited due to the presence of flatulence factors, the raffinose oligosaccharides...
  14. Siegler J, Marshall P, Bray J, Towlson C. Sodium bicarbonate supplementation and ingestion timing: does it matter?. J Strength Cond Res. 2012;26:1953-8 pubmed publisher
    ..However, VAS scores indicated that at 180 minutes postingestion, an individual is less prone to experiencing significant GI discomfort...
  15. Ding J, Liao G, Liu H, Liu S, Tang J. Meta-analysis of laparoscopy-assisted distal gastrectomy with D2 lymph node dissection for gastric cancer. J Surg Oncol. 2012;105:297-303 pubmed publisher
    ..To assess the value of laparoscopy-assisted distal gastrectomy with D2 dissection for treatment of gastric cancer...
  16. Hull T, Floruta C, Piedmonte M. Preliminary results of an outcome tool used for evaluation of surgical treatment for fecal incontinence. Dis Colon Rectum. 2001;44:799-805 pubmed
    ..The purpose of this study was to evaluate a preliminary outcome tool for fecal incontinence...
  17. Serra J, Villoria A, Azpiroz F, Lobo B, Santos J, Accarino A, et al. Impaired intestinal gas propulsion in manometrically proven dysmotility and in irritable bowel syndrome. Neurogastroenterol Motil. 2010;22:401-6, e91-2 pubmed publisher
    ..Our aim was to determine whether, and to what extent, intestinal gas propulsion is impaired in patients with manometrically proven dysmotility compared with healthy controls and patients with IBS...
  18. León Barúa R, Berendson Seminario R. [Gastrointestinal syndromes (3): flatulence (2)]. Rev Gastroenterol Peru. 2009;29:262-5 pubmed
    The second part of the article on flatulence reviewed aspects of the pathogenesis, diagnosis and treatment of this syndrome.
  19. Nichol A, Warde P, Lockwood G, Kirilova A, Bayley A, Bristow R, et al. A cinematic magnetic resonance imaging study of milk of magnesia laxative and an antiflatulent diet to reduce intrafraction prostate motion. Int J Radiat Oncol Biol Phys. 2010;77:1072-8 pubmed publisher
    ..To determine the reduction of prostate motion during a typical radiotherapy (RT) fraction from a bowel regimen comprising an antiflatulent diet and daily milk of magnesia...
  20. Bortolotti M, Levorato M, Lugli A, Mazzero G. Effect of a balanced mixture of dietary fibers on gastric emptying, intestinal transit and body weight. Ann Nutr Metab. 2008;52:221-6 pubmed publisher
    ..The aim of this study was to test a mixture of dietary fibers expressly chosen to decrease their negative properties and strengthen their positive effects...
  21. Veiga Cabello R, Toral Revuelta J, Sánchez Sánchez E, Fernández Alvaro J, Sáez Garrido J. [Indifferentiated rheumatism and/or epileptic flatulence]. An Med Interna. 2003;20:367-9 pubmed
    ..The clinical case is commented and the metheorism causes are discussed, among it, a possible variation of abdominal epilepsy as ictal flatulence, secondary to a meningioma of the right brain convexity.
  22. Stangier J, Stähle H, Rathgen K, Fuhr R. Pharmacokinetics and pharmacodynamics of the direct oral thrombin inhibitor dabigatran in healthy elderly subjects. Clin Pharmacokinet. 2008;47:47-59 pubmed
  23. Gonlachanvit S, Coleski R, Owyang C, Hasler W. Nutrient modulation of intestinal gas dynamics in healthy humans: dependence on caloric content and meal consistency. Am J Physiol Gastrointest Liver Physiol. 2006;291:G389-95 pubmed
    ..Solids stimulate early postprandial gas dynamics to the same extent as liquid meals of similar caloric content. Thus modulatory effects of meals on intestinal gas transit depend on their caloric content but not their consistency...
  24. Coco C, Valentini V, Manno A, Rizzo G, Gambacorta M, Mattana C, et al. Functional results after radiochemotherapy and total mesorectal excision for rectal cancer. Int J Colorectal Dis. 2007;22:903-10 pubmed
    ..The aim of this study was to prospectively define and measure evacuation and continence disorders after preoperative radiochemotherapy and total mesorectal excision (TME) for rectal cancer 1 year after surgery...
  25. Schluender S, Mei L, Yang H, Fleshner P. Can a meta-analysis answer the question: is mucosectomy and handsewn or double-stapled anastomosis better in ileal pouch-anal anastomosis?. Am Surg. 2006;72:912-6 pubmed
    ..This meta-analysis demonstrates that DS-IPAA offers no advantage in functional or manometric outcome when compared with HS-IPAA...
  26. Shinkai R, Hatch J, Sakai S, Mobley C, Rugh J. Masticatory performance is not associated with diet quality in Class II orthognathic surgery patients. Int J Adult Orthodon Orthognath Surg. 2001;16:214-20 pubmed
    ..Self-reported constipation was the only digestive system problem that was significantly associated with masticatory performance...
  27. Scholtens P, Alles M, Willemsen L, van den Braak C, Bindels J, Boehm G, et al. Dietary fructo-oligosaccharides in healthy adults do not negatively affect faecal cytotoxicity: a randomised, double-blind, placebo-controlled crossover trial. Br J Nutr. 2006;95:1143-9 pubmed
    ..FOS consumption resulted in a significantly higher stool frequency and in significantly more complaints of flatulence. No significant differences between the control and FOS period were observed in the mean cytotoxicity of faecal ..
  28. Landers M, McCarthy G, Savage E. Bowel symptom experiences and management following sphincter saving surgery for rectal cancer: A qualitative perspective. Eur J Oncol Nurs. 2012;16:293-300 pubmed publisher
    ..The aim of this research was to explore participants' qualitative perspectives on bowel symptom experiences and management strategies following sphincter saving surgery for rectal cancer...
  29. Sudha M, Sawant P. Effect of capsule 'UB03' containing potential probiotic strains for the treatment of patients with irritable bowel syndrome. Benef Microbes. 2011;2:229-33 pubmed publisher
    ..improvement in frequency of defecation (23%), consistency of stool, abdominal discomfort, bloating and flatulence. However, there was no significant change in abdominal pain and mucus in stool...
  30. Sandbu R, Khamis H, Gustavsson S, Haglund U. Long-term results of antireflux surgery indicate the need for a randomized clinical trial. Br J Surg. 2002;89:225-30 pubmed
    ..The aim of this study was to compare the effectiveness of laparoscopic and open procedures...
  31. Maxwell T, Taylor D, Durnal A, Wills R, Kommala D, Wade S. Safety and efficacy of a novel continence device in colostomy patients. Dis Colon Rectum. 2010;53:1422-31 pubmed publisher
    ..This study aimed to assess the safety and efficacy of a novel colostomy continence device...
  32. Farrell S, Gilmour D, Turnbull G, Schmidt M, Baskett T, Flowerdew G, et al. Overlapping compared with end-to-end repair of third- and fourth-degree obstetric anal sphincter tears: a randomized controlled trial. Obstet Gynecol. 2010;116:16-24 pubmed publisher
    ..To compare overlapping repair with end-to-end repair of obstetric tears and to investigate which procedure results in a higher rate of flatal incontinence...
  33. Massey R. A randomized trial of rocking-chair motion on the effect of postoperative ileus duration in patients with cancer recovering from abdominal surgery. Appl Nurs Res. 2010;23:59-64 pubmed publisher
    ..Participants in the experimental group had shorter duration of POI, no effect on medication use, and time to discharge...
  34. Le Nevé B, Posserud I, Bohn L, Guyonnet D, Rondeau P, Tillisch K, et al. A combined nutrient and lactulose challenge test allows symptom-based clustering of patients with irritable bowel syndrome. Am J Gastroenterol. 2013;108:786-95 pubmed publisher
  35. Trowbridge E, Morgan D, Trowbridge M, Delancey J, Fenner D. Sexual function, quality of life, and severity of anal incontinence after anal sphincteroplasty. Am J Obstet Gynecol. 2006;195:1753-7 pubmed
    ..The purpose of this study was to determine the severity of anal incontinence and its impact on quality of life and sexual function in women after anal sphincteroplasty...
  36. Tornero Campello G. Letter 1: Randomized clinical trial of the effect of postoperative intravenous fluid restriction on recovery after elective colorectal surgery (Br J Surg 2006; 93: 1469-1474). Br J Surg. 2007;94:382; author reply 383 pubmed
  37. Queiroz K, de Oliveira A, Helbig E, Reis S, Carraro F. Soaking the common bean in a domestic preparation reduced the contents of raffinose-type oligosaccharides but did not interfere with nutritive value. J Nutr Sci Vitaminol (Tokyo). 2002;48:283-9 pubmed
    The objective of this study was to verify the effect of soaking on the factors causing flatulence in the common bean (Phaseolus vulgaris, L.) cv. IAC-Carioca during domestic preparation...
  38. Passos M, Serra J, Azpiroz F, Tremolaterra F, Malagelada J. Impaired reflex control of intestinal gas transit in patients with abdominal bloating. Gut. 2005;54:344-8 pubmed
    ..Furthermore, we have previously shown that intestinal gas transit is normally accelerated by rectal distension. We hypothesise that in patients with functional bloating this modulatory mechanism fails and impairs gas transit...
  39. Wilhelm S, Brubaker C, Varcak E, Kale Pradhan P. Effectiveness of probiotics in the treatment of irritable bowel syndrome. Pharmacotherapy. 2008;28:496-505 pubmed publisher
    ..the effectiveness of probiotics in the global relief of symptoms associated with IBS and in the improvement of flatulence, abdominal pain, transit time, and bacterial counts...
  40. Zhang Q, Zhao P. Influence of gum chewing on return of gastrointestinal function after gastric abdominal surgery in children. Eur J Pediatr Surg. 2008;18:44-6 pubmed publisher
    ..The study was designed to investigate the influence of gum chewing on the return of gastrointestinal function after gastric abdominal surgery in children and the action of neural and humoral hormones in the mechanism of gum chewing...
  41. Mortensen P. [Neutral and malodorous flatulence in obesity]. Ugeskr Laeger. 2004;166:505; author reply 505 pubmed
  42. Sareban M, Zügel D, Koehler K, Hartveg P, Zügel M, Schumann U, et al. Carbohydrate Intake in Form of Gel Is Associated With Increased Gastrointestinal Distress but Not With Performance Differences Compared With Liquid Carbohydrate Ingestion During Simulated Long-Distance Triathlon. Int J Sport Nutr Exerc Metab. 2016;26:114-22 pubmed publisher
    ..Athletes should consider this a potential disadvantage of GEL administration during long-distance triathlon. ..
  43. Magistro C, Lernia S, Ferrari G, Zullino A, Mazzola M, De Martini P, et al. Totally laparoscopic versus laparoscopic-assisted right colectomy for colon cancer: is there any advantage in short-term outcomes? A prospective comparative assessment in our center. Surg Endosc. 2013;27:2613-8 pubmed publisher
    ..The purpose of this study was to determine prospectively if TLC offers some advantages in short-term outcomes over LAC...
  44. Murray R, Bryant A, Leng R. Rates of production of methane in the rumen and large intestine of sheep. Br J Nutr. 1976;36:1-14 pubmed
    ..5. Of the methane produced in the lower digestive tract, 89 +/- 2-3% was excreted through the lungs and 11% through the anus...
  45. Buemann B, Toubro S, Astrup A. Human gastrointestinal tolerance to D-tagatose. Regul Toxicol Pharmacol. 1999;29:S71-7 pubmed
    ..1 and 31.5%, respectively, in 73 healthy young male subjects in a screening study. Increased flatulence after D-tagatose was frequently reported in all the studies and the flatulence did not decline during a 15-day ..
  46. Westermarck E, Wiberg M. Effects of diet on clinical signs of exocrine pancreatic insufficiency in dogs. J Am Vet Med Assoc. 2006;228:225-9 pubmed
    ..To assess the effects of dietary modification on clinical signs of exocrine pancreatic insufficiency (EPI) in dogs...
  47. Garcia X, Soler L, Amer M, Camacho J, Arnalich F. [Twenty one year old male with cachexia and presence of abundant amount of intraabdominal gas]. Rev Clin Esp. 2006;206:355-6 pubmed
  48. Infante D, Segarra O, Luyer B. Dietary treatment of colic caused by excess gas in infants: biochemical evidence. World J Gastroenterol. 2011;17:2104-8 pubmed publisher
    ..To evaluate the impact of feeding colicky infants with an adapted formula on the hydrogen breath test and clinical symptoms...
  49. Schjoldager B, Sørensen J, Svaerke T, Berthelsen J. [Ogilvie syndrome after Cesarean section]. Ugeskr Laeger. 2001;163:3064-8 pubmed
    ..Ogilvie's syndrome, acute pseudo-obstruction of the colon, can lead to perforation of the caecum and death. The syndrome is not well known and diagnosis can be difficult to make in time...
  50. Caporaso N, Morisco F, Penagini R. [Functional intestinal disorders: how to improve diagnosis and treatment in general practice]. Minerva Gastroenterol Dietol. 2010;56:101-20 pubmed
    ..However, intestinal functional disorders are not associated with dangerous sequelae or mortality. It is up to general practitioners to reassure patients and to prescribe first-level diagnostic exams appropriately...
  51. Stewart M, Nikhanj S, Timm D, Thomas W, Slavin J. Evaluation of the effect of four fibers on laxation, gastrointestinal tolerance and serum markers in healthy humans. Ann Nutr Metab. 2010;56:91-8 pubmed publisher
    ..Average dietary fiber intake in the United States is roughly half of the recommended amount. As new dietary fiber products are introduced to increase fiber intake, it is critical to evaluate the physiological effects of such fibers...
  52. Koldjeski D, Kirkpatrick M, Everett L, Brown S, Swanson M. Health seeking related to ovarian cancer. Cancer Nurs. 2004;27:370-8; quiz 379-80 pubmed
    ..Nurses and primary care providers need frequent continuing education updates and the health media need current and accurate information about this malignancy...
  53. Hanauer S, DuPont H, Cooper K, Laudadio C. Randomized, double-blind, placebo-controlled clinical trial of loperamide plus simethicone versus loperamide alone and simethicone alone in the treatment of acute diarrhea with gas-related abdominal discomfort. Curr Med Res Opin. 2007;23:1033-43 pubmed