chills

Summary

Summary: The sudden sensation of being cold. It may be accompanied by SHIVERING.

Top Publications

  1. Kager P, van Gorp E, van Thiel P. [Fever and chills due to leptospirosis after travel to Thailand]. Ned Tijdschr Geneeskd. 2001;145:184-6 pubmed
    Two weeks after rafting on a river in Thailand a Dutch 54-year-old male experienced chills and high fever. While rafting he had wounded his hand...
  2. Grewe O, Kopiez R, Altenmüller E. Chills as an indicator of individual emotional peaks. Ann N Y Acad Sci. 2009;1169:351-4 pubmed publisher
    b>Chills (goose bumps) have been repeatedly associated with positive emotional peaks. Chills seem to be related to distinct musical structures and the reward system in the brain...
  3. Grewe O, Nagel F, Kopiez R, Altenmüller E. How does music arouse "chills"? Investigating strong emotions, combining psychological, physiological, and psychoacoustical methods. Ann N Y Acad Sci. 2005;1060:446-9 pubmed
    ..quot; We recorded chills both via subjects' self-reports and physiological reactions, finding that they do not occur in a reflex-like ..
  4. Tokuda Y, Miyasato H, Stein G, Kishaba T. The degree of chills for risk of bacteremia in acute febrile illness. Am J Med. 2005;118:1417 pubmed
    Patients with acute febrile illness may experience different degrees of chills. To evaluate the different degrees of chills in predicting risk of bacteremia in patients with acute febrile illness, we performed a single-center prospective ..
  5. Hoogendoorn M, van t Wout J, Schijf V, Van Dissel J. [Predictive value of chills in patients presenting with fever to urgent care department]. Ned Tijdschr Geneeskd. 2002;146:116-20 pubmed
    To ascertain the correlation between chills, bacteraemia, infection type and clinical progress in patients presenting with fever to the casualty department.
  6. Listernick R. A 17-year-old girl with fever, chills, rib, and pelvic pain. Pediatr Ann. 2008;37:123-6 pubmed
  7. Patton T, Jukic D, Juhas E. Atypical histopathology in bowel-associated dermatosis-arthritis syndrome: A case report. Dermatol Online J. 2009;15:3 pubmed
    Bowel-associated dermatosis-arthritis syndrome (BADAS) is characterized by a prodrome of fever, chills, and flu-like symptoms with subsequent skin eruptions, myalgias, and polyarthralgias...
  8. O Brien S, Kantarjian H, Thomas D, Giles F, Freireich E, Cortes J, et al. Rituximab dose-escalation trial in chronic lymphocytic leukemia. J Clin Oncol. 2001;19:2165-70 pubmed
  9. Choure A, Shrestha R, Larosa S, Mehta A. Fever, chills, and chest radiographic infiltrates in a middle-aged woman. Cleve Clin J Med. 2005;72:367-9, 373-4 pubmed

More Information

Publications62

  1. Van Dissel J, Numan S, van t Wout J. Chills in 'early sepsis': good for you?. J Intern Med. 2005;257:469-72 pubmed
    We evaluated the predictive value of chills, bacteraemia and endotoxaemia for in-hospital mortality and survival at 5-10 years long-term follow-up in a prospective cohort of 'early sepsis' patients presenting with fever resulting from ..
  2. Vento J, Arici M, Spencer R, Sood R. F-18 FDG PET: mottled splenomegaly with remission of symptoms after splenectomy in sarcoidosis. Clin Nucl Med. 2004;29:103-4 pubmed
  3. Reess J, Haas J, Gabriel K, Fuhlrott A, Fiola M. Both paracetamol and ibuprofen are equally effective in managing flu-like symptoms in relapsing-remitting multiple sclerosis patients during interferon beta-1a (AVONEX) therapy. Mult Scler. 2002;8:15-8 pubmed
    ..These results indicate that neither the paracetamol nor the ibuprofen treatment regimen is better...
  4. Zou Y, Ni Y, Liu X, Chen X. Misdiagnosis of Behçet's disease with unknown protracted fever and chill after surgical excision of cardiac tumor. Rheumatol Int. 2012;32:2177-9 pubmed publisher
    ..After case review the diagnosis of Behçet's disease was established and the patient was treated with glucocorticoids which resulted in resolution...
  5. Guertler C, Wirz B, Christ Crain M, Zimmerli W, Mueller B, Schuetz P. Inflammatory responses predict long-term mortality risk in community-acquired pneumonia. Eur Respir J. 2011;37:1439-46 pubmed publisher
    ..3, 1.7-6.2). Initial presentation with temperature>38.7°C (0.4, 0.2-0.6), chills (0.6, 0.4-0.99) and highest quartile of the inflammatory marker C-reactive-protein (0.3, 0.2-0...
  6. Dodd G, Napier D, Schoolfield J, Hubbard L. Percutaneous radiofrequency ablation of hepatic tumors: postablation syndrome. AJR Am J Roentgenol. 2005;185:51-7 pubmed
    ..Our objective was to define the spectrum and possible predictors of symptoms that occur in patients after percutaneous radiofrequency ablation of hepatic tumors...
  7. Vollaard A, Ali S, Widjaja S, Asten H, Visser L, Surjadi C, et al. Identification of typhoid fever and paratyphoid fever cases at presentation in outpatient clinics in Jakarta, Indonesia. Trans R Soc Trop Med Hyg. 2005;99:440-50 pubmed
    ..treatment and advice on hygiene measures in patients with suspected (para)typhoid fever should take into account chills and absence of cough in the first week of fever and delirium in the second week of illness...
  8. Khan Z, Arab S, Emami B. Comparison of the effects of anesthesia with isoflurane and total intravenous anesthesia on the intensity of body temperature reduction during anesthesia and incidence of postoperative chills. Acta Med Iran. 2011;49:425-32 pubmed
    ..total intravenous anesthesia) on the intensity of body temperature reduction during anesthesia and incidence of chills after lumbar disc surgery. The study was done as a single blinded randomized clinical trial...
  9. Ikematsu Y. Characteristics of and interventions for fever in Japan. Int Nurs Rev. 2004;51:229-39 pubmed
  10. Rose A, Patel U, Chu J, Patel R, Meehan S, Latkowski J. Erythrodermic lichen planus. Dermatol Online J. 2011;17:26 pubmed
    ..We discuss the treatment options for generalized LP and the evidence in support of these agents...
  11. Renaudier P, Brunie J, Vial J, Campergue L, Augey L, Arnuti B, et al. [Evaluation of adherence to the regulations for declaration of notification of transfusion reactions with fever and chills. A study of the Association Inter-Régionale du Sud-Est d'Hémovigilance (AIRSEH)]. Transfus Clin Biol. 2003;10:324-30 pubmed
    ..Moreover, the non-conformity concerns first of all benign FNHTR. A stronger separation between alert and epidemiological surveillance is proposed in order to improve the notifications' conformity...
  12. Giles F, Cortes J, Halliburton T, Mallard S, Estey E, Waddelow T, et al. Intravenous corticosteroids to reduce gemtuzumab ozogamicin infusion reactions. Ann Pharmacother. 2003;37:1182-5 pubmed
    ..To assess whether the addition of a brief course of intravenous corticosteroids reduces the incidence of infusion-related adverse events associated with gemtuzumab ozogamicin (GO) administration...
  13. Daily J, Waldron M. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 22-2003. A 22-year-old man with chills and fever after a stay in South America. N Engl J Med. 2003;349:287-95 pubmed
  14. O Day S, Agarwala S, Naredi P, Kass C, Gehlsen K, Glaspy J. Treatment with histamine dihydrochloride and interleukin-2 in patients with advanced metastatic malignant melanoma: a detailed safety analysis. Melanoma Res. 2003;13:307-11 pubmed
    ..Study-related deaths were low and were not impacted by the addition of histamine to the IL2 regimen...
  15. Saidinejad M, Burns M, Harper M. Disseminated histoplasmosis in a nonendemic area. Pediatr Infect Dis J. 2004;23:781-2 pubmed
    ..Use of effective diagnostic tools such as Histoplasma antigen detection can aid in providing timely and appropriate therapy...
  16. Petitpain N, Goffinet L, Cosserat F, Trechot P, Cuny J. Recurrent fever, chills, and arthralgia with local anesthetics containing epinephrine-metabisulfite. J Clin Anesth. 2008;20:154 pubmed publisher
  17. Melby M. Chilliness: a vasomotor symptom in Japan. Menopause. 2007;14:752-9 pubmed
  18. Hubel K, Dale D, Liles W. Therapeutic use of cytokines to modulate phagocyte function for the treatment of infectious diseases: current status of granulocyte colony-stimulating factor, granulocyte-macrophage colony-stimulating factor, macrophage colony-stimulating factor, and. J Infect Dis. 2002;185:1490-501 pubmed
    ..However, variable therapeutic efficacy has been reported in clinical trials conducted to date. This review summarizes the current status of the use of G-CSF, GM-CSF, M-CSF, and IFN-gamma in the treatment of infectious diseases...
  19. Ushiroyama T, Sakuma K, Nosaka S. Comparison of effects of vitamin E and wen-jing-tang (unkei-to), an herbal medicine, on peripheral blood flow in post-menopausal women with chilly sensation in the lower extremities: a randomized prospective study. Am J Chin Med. 2006;34:969-79 pubmed
    ..It also showed that this herbal medicine suppresses excessive blood flow through the upper half of the body and thus stimulates restoration of physiological distribution of blood flow throughout the entire body...
  20. Raza A, Jurcic J, Roboz G, Maris M, Stephenson J, Wood B, et al. Complete remissions observed in acute myeloid leukemia following prolonged exposure to lintuzumab: a phase 1 trial. Leuk Lymphoma. 2009;50:1336-44 pubmed publisher
    ..The most common adverse event was transient chills with the initial lintuzumab infusion (39%)...
  21. Patterson B, Freedman J, Blanchette V, Sher G, Pinkerton P, Hannach B, et al. Effect of premedication guidelines and leukoreduction on the rate of febrile nonhaemolytic platelet transfusion reactions. Transfus Med. 2000;10:199-206 pubmed
    ..provided baseline information on the use of premedications and the rate of platelet transfusion reactions (fever, chills, rigors and hives)...
  22. Talani P, Samba G, Moyen G. [Management of child fever in the battle against malaria in Brazzaville]. Bull Soc Pathol Exot. 2002;95:47-9 pubmed
    ..8%), asthenia (79.9%), chills (21.1%), vomiting (25.1%) and diarrhoea (10.9%)...
  23. Gagné A, Guilbert E, Ouellet J, Roy V, Tremblay J. Assessment of pain after elective abortion relating to the use of misoprostol for dilatation of the cervix. J Obstet Gynaecol Can. 2010;32:244-53 pubmed
  24. Carder M, McNamee R, Beverland I, Elton R, Cohen G, Boyd J, et al. The lagged effect of cold temperature and wind chill on cardiorespiratory mortality in Scotland. Occup Environ Med. 2005;62:702-10 pubmed
    ..To investigate the lagged effects of cold temperature on cardiorespiratory mortality and to determine whether "wind chill" is a better predictor of these effects than "dry bulb" temperature...
  25. Faris J, Brown C. Time tells the tale. Am J Med. 2005;118:840-2 pubmed
  26. Charles R, Goh S. Not just gastroenteritis: thyroid storm unmasked. Emerg Med Australas. 2004;16:247-9 pubmed
    ..We present a case where suspected infective gastroenteritis in a newly diagnosed diabetic masked the major symptomatology of thyroid storm, and review the diagnosis and management of thyrotoxic crisis...
  27. Ojha B, Muthukrishnan A, Raman A, Satya R, Mahone T, Forero Torres A. Diffuse F-18 FDG uptake in skeletal muscles secondary to chills resulting from sepsis: a cause for underestimation of viable tumor. Clin Nucl Med. 2004;29:600-1 pubmed
  28. Kara A, Turgut S, Cagli A, Sahin F, Oran E, Tunc B. Complications of therapeutic apheresis in children. Transfus Apher Sci. 2013;48:375-6 pubmed publisher
    ..Since the equipment of therapeutic apheresis is prepared for adults, the use of it in children may lead to higher complication risks and there are little data in children undergoing therapeutic apheresis...
  29. Yamada N, Yoshimura H. [Determinants of chilliness among young women and their application to psychopharmacological trials]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2009;29:171-9 pubmed
    ..We used a new questionnaire to determine complaint severity with regard to chills and assessed physical parameters (BMI, body fat ratio, basal metabolism, blood pressure), peripheral circulation, ..
  30. Kjaersgaard M, Edslev P, Hasle H. Subcutaneous anti-D treatment of idiopathic thrombocytopenic purpura in children. Pediatr Blood Cancer. 2009;53:1315-7 pubmed publisher
    ..01). The median decline in hemoglobin was 1.3 g/dl. Two children experienced minor fever and chills within 24 hr of treatment...
  31. Lamparter S, Waldhans S. Enterococcus septicemia due to a pacemaker lead infection. J Cardiovasc Med (Hagerstown). 2012;13:651-2 pubmed publisher
    ..We report the case of an 80-year-old pacemaker-dependent female patient with complete heart block, who presented with subfebrile temperatures and chills due to a pacemaker lead infection by Enterococcus faecalis.
  32. Li W, Frohwein T, Ong K. Cardiac tamponade as an initial presentation for systemic lupus erythematosus. Am J Emerg Med. 2017;35:1213.e1-1213.e4 pubmed publisher
    ..male with complaints of acute onset shortness of breath and generalized body aches associated with a fever and chills in the ER...
  33. Bonilla M, Kaul D, Saint S, Isada C, Brotman D. Clinical problem-solving. Ring around the diagnosis. N Engl J Med. 2006;354:1937-42 pubmed
  34. Olencki T, Peereboom D, Wood L, Budd G, Novick A, Finke J, et al. Phase I and II trials of subcutaneously administered rIL-2, interferon alfa-2a, and fluorouracil in patients with metastatic renal carcinoma. J Cancer Res Clin Oncol. 2001;127:319-24 pubmed
    ..A phase I followed by a phase II trial utilizing rIL-2, IFN alpha, and 5-FU were conducted in patients with unresectable and/or metastatic renal cell carcinoma...
  35. Mendiolaza J, Dhruva V, Pinho P, Reteguiz J, Kapila R. A thirty-six-year-old male with fever, chills, and weight loss. N J Med. 2004;101:11-5 pubmed
  36. Sanders R, Maddirala S, Geiger T, Pounds S, Sandlund J, Ribeiro R, et al. Premedication with acetaminophen or diphenhydramine for transfusion with leucoreduced blood products in children. Br J Haematol. 2005;130:781-7 pubmed
    ..Febrile and allergic transfusion reactions were rare in paediatric patients transfused with leucoreduced, irradiated blood products, whether premedication was used or not...
  37. Philip N, Winikoff B, Moore K, Blumenthal P. A consensus regimen for early abortion with misoprostol. Int J Gynaecol Obstet. 2004;87:281-3 pubmed
  38. Prévill X, Sick E, Beauchard S, Ossevoort M, Tiollier J, Revillard J, et al. 6-Methylprednisolone does not impair anti-thymocyte globulin (ATG) immunosuppressive activity in non-human primates. Transpl Immunol. 2001;9:57-61 pubmed
    ..Since ATG can trigger Fas (CD95) mediated T cell apoptosis, a process antagonized in vitro by corticosteroids, an important issue is whether corticosteroids could interfere with T cell depleting and immunosuppressive activities of ATG...
  39. Graber C, Lauring A, Chin Hong P. Clinical problem-solving. A stitch in time--a 64-year-old man with a history of coronary artery disease and peripheral vascular disease was admitted to the hospital with a several-month history of fevers, chills, and fatigue. N Engl J Med. 2007;357:1029-34 pubmed
  40. Anwer K, Kelly F, Chu C, Fewell J, Lewis D, Alvarez R. Phase I trial of a formulated IL-12 plasmid in combination with carboplatin and docetaxel chemotherapy in the treatment of platinum-sensitive recurrent ovarian cancer. Gynecol Oncol. 2013;131:169-73 pubmed publisher
  41. Kim S, Chang Y, Cho H, Hwang Y, Moon Y. Non-steroidal anti-inflammatory drugs for the common cold. Cochrane Database Syst Rev. 2013;:CD006362 pubmed publisher
    ..Non-steroidal anti-inflammatory drugs (NSAIDs) have been widely used for the treatment of pain and fever associated with the common cold. However, there is no systematic review to assess the effects of NSAIDs in treating the common cold...
  42. Egea A, Vilaro M, de la Fuente J, Cuestas E, Bongiovanni M. [Predictive ability of clinical parameters of bacteremia in hemodialysed patients]. Rev Fac Cien Med Univ Nac Cordoba. 2012;69:135-8 pubmed
    ..No clinical events to differentiate bacteteremia from other pathologies in hemodialysis patients therefore the physicians makes diagnosis and treatment decisions based on clinical evidence an local epidemiology...
  43. Mato M, Perez A, Otero J, De Antonio P, Marquez C, Torres L. [Incidence of postoperative shivering in relation to the time of sevoflurane discontinuation]. Rev Esp Anestesiol Reanim. 2002;49:197-200 pubmed
    ..We aimed to determine whether early termination of sevoflurane administration lowers the incidence of postanesthetic shivering...
  44. Coburn B, Morris A, Tomlinson G, Detsky A. Does this adult patient with suspected bacteremia require blood cultures?. JAMA. 2012;308:502-11 pubmed publisher
    ..Clinicians order blood cultures liberally among patients in whom bacteremia is suspected, though a small proportion of blood cultures yield true-positive results. Ordering blood cultures inappropriately may be both wasteful and harmful...
  45. Thakur C, Kumar A, Mitra D, Roy A, Sinha A, Ranjan A. Improving outcome of treatment of kala-azar by supplementation of amphotericin B with physiologic saline and potassium chloride. Am J Trop Med Hyg. 2010;83:1040-3 pubmed publisher
  46. Batsis J, Uslan D, Baddour L. 70-year-old man with fever, shaking chills, and weakness. Mayo Clin Proc. 2005;80:1209-12 pubmed
  47. Laurie S, Bell J, Atkins H, Roach J, Bamat M, O Neil J, et al. A phase 1 clinical study of intravenous administration of PV701, an oncolytic virus, using two-step desensitization. Clin Cancer Res. 2006;12:2555-62 pubmed
    ..This study tested the hypothesis that two-step desensitization, using two dose increments before high repeat doses, would be well tolerated...
  48. McLachlan M, Weissman K, Nadel E, Brown D. Intermittent fevers. J Emerg Med. 2006;30:425-8 pubmed
  49. Yamada N, Nishihara C, Yoshimura H, Yamaguchi Y, Takagaki R, Miyakoshi M, et al. [Effects of Piper longum L. on chills in Japanese young women: time-dependent changes in skin surface temperature and its recovery rate following the exposure to mild cold stress]. Nihon Shinkei Seishin Yakurigaku Zasshi. 2009;29:7-15 pubmed
    b>Chills can lead to problems such as insomnia, mental fatigue, and unstable emotions. Increasing evidence shows that young women, as well as menopausal women, suffer from chills. The present study investigated the effect of Piper longum L...
  50. Tsou T, Shao P, Lu C, Chang L, Kao C, Lee P, et al. Viral load and clinical features in children infected with seasonal influenza B in 2006/2007. J Formos Med Assoc. 2012;111:83-7 pubmed publisher
    ..We conducted a study to assess the relationship between virus load and clinical features in children infected with influenza B, in the hope that clinical features could be used as surrogate markers of viral load to guide treatment...
  51. Nasir J, Roy M. A 43-year-old colonel with chills, diaphoresis, and headache. Mil Med. 2006;171:340-3 pubmed
  52. Baqer M, Qurtom M, Abdulhadi Ali Al Ajmi J, Collier B, Elgazzar A. Multifocal brucellosis spondylodiscitis. Clin Nucl Med. 2002;27:842-3 pubmed
  53. Kopterides P, Sklirou E. A word on chills. Am J Med. 2007;120:e21; author reply e23 pubmed