Summary: Formation of an infarct, which is NECROSIS in tissue due to local ISCHEMIA resulting from obstruction of BLOOD CIRCULATION, most commonly by a THROMBUS or EMBOLUS.

Top Publications

  1. MacDonald R, Kassell N, Mayer S, Ruefenacht D, Schmiedek P, Weidauer S, et al. Clazosentan to overcome neurological ischemia and infarction occurring after subarachnoid hemorrhage (CONSCIOUS-1): randomized, double-blind, placebo-controlled phase 2 dose-finding trial. Stroke. 2008;39:3015-21 pubmed publisher
  2. Perez de la Ossa N, Hernandez Perez M, Domenech S, Cuadras P, Massuet A, Millan M, et al. Hyperintensity of distal vessels on FLAIR is associated with slow progression of the infarction in acute ischemic stroke. Cerebrovasc Dis. 2012;34:376-84 pubmed publisher
    ..Our aim was to study the association of the HV sign with progression of infarction in acute stroke patients.
  3. Maternini M, Pezzetta E, Martinet O. Laparoscopic approach for idiopathic segmental infarction of the greater omentum. Minerva Chir. 2009;64:225-7 pubmed
    Idiopathic segmental infarction of the greater omentum is an uncommon condition that should be considered in the differential diagnosis of right-side abdominal pain...
  4. Rimon A, Daneman A, Gerstle J, Ratnapalan S. Omental infarction in children. J Pediatr. 2009;155:427-431.e1 pubmed publisher
    To analyze the clinical presentation, radiologic features, management, and outcome in children diagnosed with omental infarction.
  5. Wang C, Tsai W, Lo Y, Chen J, Wong A. Unilateral right occipital condyle to C2 level spinal cord infarction associated with ipsilateral vertebral artery stenosis and contralateral vertebral artery dissection: a case report. J Spinal Cord Med. 2011;34:118-21 pubmed
    To illustrate the clinical presentation, diagnosis, management, and outcome of unilateral right occipital condyle to C2 level spinal cord infarction.
  6. Bande D, Abbara S, Kalva S. Acute renal infarction secondary to calcific embolus from mitral annular calcification. Cardiovasc Intervent Radiol. 2011;34:647-9 pubmed publisher
    ..We briefly review the literature and discuss the importance of this entity in clinical practice...
  7. Chen Y, Chen W, Tsai W, Tsao Y. Sentinel central retinal artery occlusion: a forme fruste of idiopathic renal infarction. Am J Emerg Med. 2009;27:253.e1-2 pubmed publisher
    ..of amaurosis fugax secondary to sentinel central retinal artery occlusion followed by acute idiopathic renal infarction. This patient highlights that the preceding visual events could portend a devastating thromboembolic insult in ..
  8. Moschetta M, Stabile Ianora A, Pedote P, Scardapane A, Angelelli G. Prognostic value of multidetector computed tomography in bowel infarction. Radiol Med. 2009;114:780-91 pubmed publisher
    This study aimed to correlate computed tomography (CT) findings and outcomes in patients affected by bowel infarction.
  9. McLeod D. Central retinal vein occlusion with cilioretinal infarction from branch flow exclusion and choroidal arterial steal. Retina. 2009;29:1381-95 pubmed publisher
    The first definitive study of retinal vein occlusion complicated by infarction within the territory of one or more cilioretinal arteries was published in 1976...

More Information


  1. Hayn M, Herz D, Bellinger M, Schneck F. Intermittent torsion of the spermatic cord portends an increased risk of acute testicular infarction. J Urol. 2008;180:1729-32 pubmed publisher
  2. Ganesh A, Al Zuhaibi S, Pathare A, William R, Al Senawi R, Al Mujaini A, et al. Orbital infarction in sickle cell disease. Am J Ophthalmol. 2008;146:595-601 pubmed publisher
    To determine the role of hematological and genetic factors in the development of orbital infarction in sickle cell disease.
  3. Sasmal P, Tantia O, Patle N, Khanna S. Omental torsion and infarction: a diagnostic dilemma and its laparoscopic management. J Laparoendosc Adv Surg Tech A. 2010;20:225-9 pubmed publisher
    ..of the omentum, described variously as acute epiploitis, primary omental torsion, idiopathic segmental infarction, etc...
  4. Beneke S. Poly(ADP-ribose) polymerase activity in different pathologies--the link to inflammation and infarction. Exp Gerontol. 2008;43:605-14 pubmed publisher
    ..This review provides an introduction into the wide and complex field of poly(ADP-ribosyl)ation in different pathologies with regards of cell death regulation, inflammation and resulting tissue damage...
  5. Paiva M, Goncalves L, Providencia L, Davidson S, Yellon D, Mocanu M. Transitory activation of AMPK at reperfusion protects the ischaemic-reperfused rat myocardium against infarction. Cardiovasc Drugs Ther. 2010;24:25-32 pubmed publisher
    ..Two known AMPK activators (metformin and AICAR) were used to verify the hypothesis that a transitory activation of AMPK at reperfusion may exert cardioprotection, as reflected in a reduction in myocardial infarct size...
  6. Dreischalück J, Schwöppe C, Spieker T, Kessler T, Tiemann K, Liersch R, et al. Vascular infarction by subcutaneous application of tissue factor targeted to tumor vessels with NGR-peptides: activity and toxicity profile. Int J Oncol. 2010;37:1389-97 pubmed
    ..Thus, subcutaneous injection of tTF-NGR represents an active, but toxic application procedure and compares unfavourably to intravenous infusion...
  7. Kantarci F, Cebi Olgun D, Mihmanli I. Shear-wave elastography of segmental infarction of the testis. Korean J Radiol. 2012;13:820-2 pubmed publisher
    Segmental testicular infarction (STI) is a rare cause of acute scrotum...
  8. Ambrosio M, Rocca B, Ginori A, Onorati M, Fabbri A, Carmellini M, et al. Renal infarction due to polyarteritis nodosa in a patient with angioimmunoblastic T-cell lymphoma: a case report and a brief review of the literature. Diagn Pathol. 2012;7:50 pubmed publisher
    ..A careful evaluation is needed in the management of angioimmunoblastic T-cell lymphoma patients with signs of renal failure in order to avoid delay of treatment and organ damage...
  9. Bertolotto M, Derchi L, Sidhu P, Serafini G, Valentino M, Grenier N, et al. Acute segmental testicular infarction at contrast-enhanced ultrasound: early features and changes during follow-up. AJR Am J Roentgenol. 2011;196:834-41 pubmed publisher
    The purpose of this retrospective study was to assess whether contrast-enhanced ultrasound is useful for characterization of acute segmental testicular infarction.
  10. Kim H, Goske M, Bove K, Minovich E. Segmental testicular infarction in a young man simulating a testicular tumor. Pediatr Radiol. 2009;39:400-2 pubmed publisher
    ..a wedge-shaped, heterogeneous, avascular testicular mass diagnosed preoperatively as a segmental testicular infarction (STI). This was proved at surgery and subsequent histology...
  11. Kim J, Cho K, Lee H. Isolated labyrinthine infarction as a harbinger of anterior inferior cerebellar artery territory infarction with normal diffusion-weighted brain MRI. J Neurol Sci. 2009;278:82-4 pubmed publisher
    This paper aims to determine the frequency of isolated labyrinthine infarction as an initial manifestation of anterior inferior cerebellar artery (AICA) territory infarction and discuss its clinical implication.
  12. Bestman T, Valk J, Gypen B, Declercq S, Hendrickx L. An unusual complication after Roux-en-Y gastric bypass: torsion and infarction of the divided Omentum. Obes Surg. 2009;19:1731-3 pubmed publisher
    ..An abdominal computed tomography scan showed signs of omental infarction. A laparoscopy was performed and showed a torsion and infarction of the divided greater omentum...
  13. Joshi R, Reen B, Sheehan H. Upper extremity diabetic muscle infarction in three patients with end-stage renal disease: a case series and review. J Clin Rheumatol. 2009;15:81-4 pubmed publisher
    Diabetic muscle infarction is a rare complication of diabetes. Since first reported in 1965, approximately 130 patients have been reported, with only 2 cases described affecting the upper extremity...
  14. Blair E, de Groot J, Nelson K. Placental infarction identified by macroscopic examination and risk of cerebral palsy in infants at 35 weeks of gestational age and over. Am J Obstet Gynecol. 2011;205:124.e1-7 pubmed publisher
    We sought to investigate whether placental infarction determined by macroscopic examination was associated with risk of cerebral palsy (CP).
  15. Doody O, Adam W, Foley P, Lyon S. Fibromuscular dysplasia presenting with bilateral renal infarction. Cardiovasc Intervent Radiol. 2009;32:329-32 pubmed publisher
    ..We report a rare case of bilateral segmental renal infarction secondary to FMD in a young male patient...
  16. Farah R, Jalkh K, Farhat H, Sayad P, Kadri A. Acquired protein C deficiency in a child with acute myelogenous leukemia, splenic, renal, and intestinal infarction. Blood Coagul Fibrinolysis. 2011;22:140-3 pubmed publisher
    ..Acquired protein C deficiency can occur in a variety of settings and has been reported in acute myelocytic leukemia. However, clinically significant thrombosis in the absence of clinical DIC, such as our case, remains extremely rare...
  17. Arends S, Coebergh J, Kerkhoffs J, van Gils A, Koppen H. Severe unilateral headache caused by skull bone infarction with epidural haematoma in a patient with sickle cell disease. Cephalalgia. 2011;31:1325-8 pubmed publisher
    ..We report a case of a man who presented with severe headache caused by an uncommon complication of SCD...
  18. Roberts S, Arthurs B. Severe visual loss and orbital infarction following periorbital aesthetic poly-(L)-lactic acid (PLLA) injection. Ophthalmic Plast Reconstr Surg. 2012;28:e68-70 pubmed publisher
    ..Angiography and further history suggested an embolic orbital infarction as the mechanism of injury...
  19. Harlander M, Bajrovic F, Blinc A, Sabovic M. Monoparesis due to spinal cord infarction associated with thoracoabdominal aneurysm. Heart Vessels. 2008;23:359-62 pubmed publisher
    We describe a case of acute monoparesis of a lower limb due to asymmetric spinal cord infarction in a patient with previously unrecognized thoracoabdominal aneurysm...
  20. Marsolais G, Peck J, Berry C, Johnson A. Femoral medullary infarction prevalence with the Zurich Cementless Canine Total Hip arthroplasty. Vet Surg. 2009;38:677-80 pubmed publisher
    To document the prevalence of femoral medullary infarction associated with the Zurich Cementless Total Hip Replacement (ZCTHR) system in dogs.
  21. Giuliani A, Mettimano M, Viviani D, Scagliusi A, Bruno A, Russo A, et al. An uncommon case of systemic Mucormycosis associated with spinal cord infarction in a recently diagnosed diabetic. Int J Immunopathol Pharmacol. 2010;23:355-8 pubmed a 54-year-old diabetic woman and evolved into a disseminated form, leading to an uncommon spinal cord infarction and consequent paraparesis...
  22. Kroencke T, Scheurig C, Poellinger A, Gronewold M, Hamm B. Uterine artery embolization for leiomyomas: percentage of infarction predicts clinical outcome. Radiology. 2010;255:834-41 pubmed publisher
    To determine the effect of partial versus complete leiomyoma infarction on relief of leiomyoma-related symptoms and freedom from invasive reinterventions and to assess if patient age, location of the dominant leiomyoma, number of ..
  23. Kumral E, Polat F, Gulluoglu H, Uzunköprü C, Tuncel R, Alpaydin S. Spinal ischaemic stroke: clinical and radiological findings and short-term outcome. Eur J Neurol. 2011;18:232-9 pubmed publisher
    ..Therefore, we assessed the pathogenetic mechanisms and short-term outcomes of the patients with spinal stroke based on clinical data and magnetic resonance imaging findings...
  24. Bourgault M, Grimbert P, Verret C, Pourrat J, Herody M, Halimi J, et al. Acute renal infarction: a case series. Clin J Am Soc Nephrol. 2013;8:392-8 pubmed publisher
    Renal infarction is an arterial vascular event that may cause irreversible damage to kidney tissues. This study describes the clinical characteristics of patients with renal infarction according to underlying mechanism of vascular injury.
  25. Wu X, Wang H, Chen F, Jin L, Li J, Feng Y, et al. Rat model of reperfused partial liver infarction: characterization with multiparametric magnetic resonance imaging, microangiography, and histomorphology. Acta Radiol. 2009;50:276-87 pubmed publisher
    Rat model of reperfused partial liver infarction (RPLI) has been increasingly used in studying new diagnostics and therapeutics.
  26. Haque M, Schumacher P, Harris A, Scudamore C, Steinbrecher U, Chung S, et al. Late acute celiac and hepatic artery thrombosis with portal vein thrombosis resulting in hepatic infarction 12 years post orthotopic liver transplantation. Ann Hepatol. 2009;8:396-9 pubmed
    ..of Wilson's disease who presented twelve years post-liver transplant symptoms typical of acute HAT and hepatic infarction. On diagnostic imaging, celiac axis and hepatic artery were thrombosed, resulting in ischemic necrosis of the ..
  27. Oh J, Cho J, Kang M, Lee J, Kwon H, Nam K, et al. Omental infarction caused by laparoscopy-assisted gastrectomy for gastric cancer: CT findings. Clin Radiol. 2011;66:966-73 pubmed publisher
    To investigate the computed tomography (CT) imaging features of omental infarction in patients who underwent laparoscopy-assisted gastrectomy (LAG) for gastric cancer.
  28. Itenberg E, Mariadason J, Khersonsky J, Wallack M. Modern management of omental torsion and omental infarction: a surgeon's perspective. J Surg Educ. 2010;67:44-7 pubmed publisher
    Omental infarction is a rare cause of acute abdomen that until recently was diagnosed only on exploratory surgery for presumed acute appendicitis or similar abdominal emergency...
  29. Hotoleanu C, Andercou O, Andercou A. Mesenteric venous thrombosis with bowel infarction and hyperhomocysteinemia due to homozygous methylenetetrahydrofolate reductase C677T genotype. Vasc Endovascular Surg. 2008;42:477-81 pubmed publisher
    The case of a 30-year-old man with bowel infarction due to mesenteric venous thrombosis and multiple risk factors, including mild hyperhomocysteinemia due to methylenetetrahydrofolate reductase C677T polymorphism and recent abdominal ..
  30. Cheng M, Lyu R, Chang Y, Chen R, Huang C, Wu T, et al. Spinal cord infarction in Chinese patients. Clinical features, risk factors, imaging and prognosis. Cerebrovasc Dis. 2008;26:502-8 pubmed publisher
    The clinical presentations, MRI findings and outcomes for spinal cord infarction (SCI) are well documented in the West but scarce in the East...
  31. Lo Giudice G, de Belvis V, Piermarocchi S, Galan A, Prosdocimo G. Acute visual loss and chorioretinal infarction after photodynamic therapy combined with intravitreal triamcinolone. Eur J Ophthalmol. 2008;18:652-5 pubmed
    ..To report acute visual loss associated with dynamic vascular changes after photodynamic therapy (PDT) combined with intravitreal triamcinolone (IVTA) for the treatment of occult choroidal neovascularization (CNV)...
  32. Rossi D, Goodwin D, Cruzzavala J. Spinal cord infarction following coronary artery bypass grafting surgery. W V Med J. 2008;104:24-5 pubmed
    ..Spinal cord infarction is infrequent, but only incomplete or indirect data are available on incidence or prevalence...
  33. Chu L, Averch T, Jackman S. Testicular infarction as a sequela of inguinal hernia repair. Can J Urol. 2009;16:4953-4 pubmed
    ..We reviewed four patients with a recent history of inguinal hernia repair and subsequently developed ischemic orchitis to evaluate management options to provide symptomatic relief and prevent testicular atrophy...
  34. Tong C, Chen J, Cochrane D. Spinal cord infarction remote from maximal compression in a patient with Morquio syndrome. J Neurosurg Pediatr. 2012;9:608-12 pubmed publisher describes a 16-year-old girl with Morquio syndrome who developed paraplegia due to thoracic spinal cord infarction during foramen magnum and atlantal decompression...
  35. Ludwig M, Burns S. Spinal cord infarction following cervical transforaminal epidural injection: a case report. Spine (Phila Pa 1976). 2005;30:E266-8 pubmed
    ..Case report...
  36. Suga S, Kim Y, Joly A, Puchacz E, Kang D, Jefferson J, et al. Vascular endothelial growth factor (VEGF121) protects rats from renal infarction in thrombotic microangiopathy. Kidney Int. 2001;60:1297-308 pubmed
    ..We hypothesized that the endothelial survival factor vascular endothelial growth factor (VEGF) may provide protection...
  37. Kim S, Miller J. Natural history and distribution of bone and bone marrow infarction in sickle hemoglobinopathies. J Nucl Med. 2002;43:896-900 pubmed
    ..Multiple examinations were performed on 21 patients. The number and distribution of total acute, healed, and nonhealed infarcts by location were recorded on a skeletal homunculus...
  38. Ho C, Devriendt H. Idiopathic segmental infarction of right sided greater omentum. Case report and review of the literature. Acta Chir Belg. 2004;104:459-61 pubmed
    Idiopathic right segmental infarction of the greater omentum is an uncommon cause of acute abdomen. The aetiology is still unclear and the symptoms mimick acute appendicitis...
  39. Kanda T, Fujii H, Tani T, Murakami H, Suda T, Sakai Y, et al. Intestinal fatty acid-binding protein is a useful diagnostic marker for mesenteric infarction in humans. Gastroenterology. 1996;110:339-43 pubmed
  40. Fragoso A, Pereira J, Estevão Costa J. Nonoperative management of omental infarction: a case report in a child. J Pediatr Surg. 2006;41:1777-9 pubmed
    Omental infarction is a rare entity in children that is usually diagnosed during surgery for suspected appendicitis...
  41. Bachar G, Shafir G, Postnikov V, Belenky A, Benjaminov O. Sonographic diagnosis of right segmental omental infarction. J Clin Ultrasound. 2005;33:76-9 pubmed
    The purpose of this study was to identify the characteristic features of omental infarction so that this entity can be differentiated from other acute conditions in the right lower quadrant of the abdomen.
  42. Madaan S, Joniau S, Klockaerts K, DeWever L, Lerut E, Oyen R, et al. Segmental testicular infarction: conservative management is feasible and safe. Eur Urol. 2008;53:441-5 pubmed
    Segmental testicular infarction is a rare cause of acute scrotum. Its aetiology is not well defined and it can be clinically confused with a testicular tumour...
  43. Van Stavern G, Gorman M. Orbital infarction after cocaine use. Neurology. 2002;59:642-3 pubmed
  44. Masci P, Dymarkowski S, Bogaert J. Images in cardiovascular medicine. Papillary muscle infarction after cardiopulmonary resuscitation. Circulation. 2007;116:e308-9 pubmed
  45. Nasser N, Abadi S, Azzam Z. Acute renal infarction from a cardiac thrombus. Nat Clin Pract Nephrol. 2007;3:631-5 pubmed
    ..His past medical history included ischemic dilated cardiomyopathy due to recurrent myocardial infarction.
  46. Ghanayem B, Long P, Ward S, Chanas B, Nyska M, Nyska A. Hemolytic anemia, thrombosis, and infarction in male and female F344 rats following gavage exposure to 2-butoxyethanol. Exp Toxicol Pathol. 2001;53:97-105 pubmed
    ..BE by inhalation and sacrificed moribund on day 4 of treatment exhibited disseminated thrombosis associated with infarction in several organs. In contrast, no such lesions were observed in male rats similarly exposed to BE...
  47. Peh W, Muttarak M. Clinics in diagnostic imaging (53). Hepatic portal venous gas due to mesenteric infarction. Singapore Med J. 2000;41:471-3 pubmed
    ..The cause was superior mesenteric artery occlusion. The aetiology, imaging features and clinical significance of hepatic portal venous gas are discussed...
  48. Abboud B, Jaoude J, Riachi M, Sleilaty G, Tabet G. Intrathoracic transverse colon and small bowel infarction in a patient with traumatic diaphragmatic hernia. Case report and review of the literature. J Med Liban. 2004;52:168-70 pubmed
    ..The aim of this study was to report a case of intrathoracic infarction of transverse colon and two meters of small bowel in a patient with traumatic diaphragmatic hernia.
  49. Ritz J, Germer C, Buhr H. Prognostic factors for mesenteric infarction: multivariate analysis of 187 patients with regard to patient age. Ann Vasc Surg. 2005;19:328-34 pubmed
    ..5 years underwent surgery for acute mesenteric infarction (AMI) in our department...
  50. Fairhead J, Phillips D, Handa A. Embolic spinal cord infarction as a presentation of abdominal aortic aneurysm. J R Soc Med. 2005;98:59-60 pubmed
  51. Kim S, Oh J, Huh K. Macular infarction after intravitreal ganciclovir injection in a patient with acute retinal necrosis. Can J Ophthalmol. 2008;43:124-5 pubmed publisher
  52. Ni Y, Adzamli K, Miao Y, Cresens E, Yu J, Periasamy M, et al. MRI contrast enhancement of necrosis by MP-2269 and gadophrin-2 in a rat model of liver infarction. Invest Radiol. 2001;36:97-103 pubmed
    ..correlation study was conducted to verify the likelihood of the proposed albumin-binding mechanism by comparing an albumin-binding blood pool agent, MP-2269, with gadophrin-2 in a rat model of reperfused liver infarction.
  53. Umpierrez G, Stiles R, Kleinbart J, Krendel D, Watts N. Diabetic muscle infarction. Am J Med. 1996;101:245-50 pubmed
    To describe the clinical, histologic, and radiologic findings in patients with diabetic muscular infarction (DMI).