Summary: The abnormal mechanisms and forms involved in the dysfunctions of tissues and organs.
Yang Y, Wang K, Gu X, Leong K. Biophysical Regulation of Cell Behavior-Cross Talk between Substrate Stiffness and Nanotopography. Engineering (Beijing). 2017;3:36-54 pubmed publisher
..We then discuss the challenges in dissecting the biophysical regulation of cell behavior and in translating the mechanistic understanding of these cues to tissue engineering and regenerative medicine...
Sapudom J, Waschke J, Franke K, Hlawitschka M, Pompe T. Quantitative label-free single cell tracking in 3D biomimetic matrices. Sci Rep. 2017;7:14135 pubmed publisher
Grabiec U, Dehghani F. N-Arachidonoyl Dopamine: A Novel Endocannabinoid and Endovanilloid with Widespread Physiological and Pharmacological Activities. Cannabis Cannabinoid Res. 2017;2:183-196 pubmed publisher
..These findings provide strong evidence that NADA is an effective agent to manage neuroinflammatory diseases or pain and can be useful in designing novel therapeutic strategies...
Wang H, Wang J, Xia Y. Defective Suppressor of Cytokine Signaling 1 Signaling Contributes to the Pathogenesis of Systemic Lupus Erythematosus. Front Immunol. 2017;8:1292 pubmed publisher
..In this review, we discuss recent studies regarding the roles of SOCS1 in the pathogenesis of SLE and its therapeutic implications...
Ershova E, Sergeeva V, Klimenko M, Avetisova K, Klimenko P, Kostyuk E, et al
. Circulating cell-free DNA concentration and DNase I activity of peripheral blood plasma change in case of pregnancy with intrauterine growth restriction compared to normal pregnancy. Biomed Rep. 2017;7:319-324 pubmed publisher
..CfDNA circulating in blood cannot be a reliable marker of increased cell death during pregnancy. Thus, assessment of the level of cell death during pregnancy should be done by simultaneous analysis of cfDNA level and DNase I activity...
Zheng X, Wang Y, Tian K, Zhou J, Guan J, Luo L, et al
. Fusing multiple protein-protein similarity networks to effectively predict lncRNA-protein interactions. BMC Bioinformatics. 2017;18:420 pubmed publisher
..Our experimental results show that the new approach outperforms the existing methods. Fusing multiple protein-protein similarity networks can effectively boost the performance of predicting lncRPIs. ..
Kaza N, Raju S, Cadillac J, Trombley J, Rasmussen L, Tang L, et al
. Use of ferrets for electrophysiologic monitoring of ion transport. PLoS ONE. 2017;12:e0186984 pubmed publisher
..airway diseases is attributed to differences in respiratory anatomy and physiology, poor approximation of pathologic processes, and lack of correlative clinical endpoints between humans and laboratory animal models...