mediastinitis

Summary

Summary: Inflammation of the mediastinum, the area between the pleural sacs.

Top Publications

  1. Wightman S, Kim A, Proia L, Faber L, Gattuso P, Warren W, et al. An unusual case of Aspergillus fibrosing mediastinitis. Ann Thorac Surg. 2009;88:1352-4 pubmed publisher
    Fibrosing mediastinitis due to Aspergillus is rare, particularly in the immunocompetent host...
  2. García de la Fuente C, Minambres E, Ugalde E, Saez A, Martinez Martinez L, Farinas M. Post-operative mediastinitis, pleuritis and pericarditis due to Mycoplasma hominis and Ureaplasma urealyticum with a fatal outcome. J Med Microbiol. 2008;57:656-7 pubmed publisher
    Post-sternotomy mediastinitis, although infrequent, is a potentially life-threatening complication of cardiac surgery...
  3. Tjardes T, Wafaizadeh A, Steinhausen E, Krakamp B, Bouillon B. Extension injury of the thoracic spine with rupture of the oesophagus and successful conservative therapy of concomitant mediastinitis. Eur Spine J. 2009;18 Suppl 2:240-4 pubmed publisher
    ..There are no systematic data on thoracic spine fractures with concomitant oesophageal perforations. Mediastinitis secondary to oesophageal perforation might be treated conservatively with endoscopic stent placement rather ..
  4. De Feo M, Della Corte A, Vicchio M, Pirozzi F, Nappi G, Cotrufo M. Is post-sternotomy mediastinitis still devastating after the advent of negative-pressure wound therapy?. Tex Heart Inst J. 2011;38:375-80 pubmed
    ..we reviewed a 15-year experience with the treatment of a severe sequela of cardiac surgery: post-sternotomy mediastinitis. We compared the outcomes of conventional treatment with those of negative-pressure wound therapy, focusing on ..
  5. Migliario M, Bello L, Greco Lucchina A, Mortellaro C. Descending necrotizing mediastinitis. Two cases consequent on odontogenic infections and a review of literature. Minerva Stomatol. 2010;59:551-60 pubmed
    b>Mediastinitis is a frequently-fatal infection of the connective tissue that surrounds the mediastinal organs...
  6. Huckfeldt R, Redmond C, Mikkelson D, Finley P, Lowe C, Robertson J. A clinical trial to investigate the effect of silver nylon dressings on mediastinitis rates in postoperative cardiac sternotomy incisions. Ostomy Wound Manage. 2008;54:36-41 pubmed
    b>Mediastinitis is a rare but serious postoperative complication of cardiac surgery that increases mortality rates, hospital length of stay, and medical costs...
  7. Baillot R, Cloutier D, Montalin L, Cote L, Lellouche F, Houde C, et al. Impact of deep sternal wound infection management with vacuum-assisted closure therapy followed by sternal osteosynthesis: a 15-year review of 23,499 sternotomies. Eur J Cardiothorac Surg. 2010;37:880-7 pubmed publisher
    ..This study was undertaken to examine the outcome of patients with deep sternal wound infection (DSWI) now treated with vacuum-assisted closure (VAC) therapy as a bridge to sternal osteosynthesis with horizontal titanium plate fixation...
  8. Schimmer C, Sommer S, Bensch M, Elert O, Leyh R. Management of poststernotomy mediastinitis: experience and results of different therapy modalities. Thorac Cardiovasc Surg. 2008;56:200-4 pubmed publisher
    Different primary treatment modalities have been utilized to treat poststernotomy mediastinitis (PM) following cardiac surgery.
  9. Toumpoulis I, Theakos N, Dunning J. Does bilateral internal thoracic artery harvest increase the risk of mediastinitis?. Interact Cardiovasc Thorac Surg. 2007;6:787-91 pubmed
    ..addressed was whether bilateral internal thoracic artery (BITA) coronary bypass increases the risk for mediastinitis. Using the reported search 140 papers were identified...

More Information

Publications66

  1. Liu J, Zhang X, Xie D, Peng A, Yang X, Yu F, et al. Acute mediastinitis associated with foreign body erosion from the hypopharynx and esophagus. Otolaryngol Head Neck Surg. 2012;146:58-62 pubmed publisher
    b>Mediastinitis secondary to hypopharyngeal and esophageal foreign bodies is a rare but lethal complication. So far, no literature on a large scale has been reported...
  2. Deniz H, Gokaslan G, Arslanoglu Y, Ozcaliskan O, Guzel G, Yasim A, et al. Treatment outcomes of postoperative mediastinitis in cardiac surgery; negative pressure wound therapy versus conventional treatment. J Cardiothorac Surg. 2012;7:67 pubmed publisher
    The aim of the present study is to compare negative pressure wound therapy versus conventional treatment outcomes at postoperative mediastinitis after cardiac surgery.
  3. Melo C, Sarmento P, Imaeda C, Daud D, Hasimoto F, Leão L. Descending necrotizing mediastinitis: minimally invasive thoracic surgical treatment. J Bras Pneumol. 2010;36:812-8 pubmed
    To report a case series of patients with descending necrotizing mediastinitis (DNM) who were treated with minimally invasive thoracic surgery.
  4. Kagen J, Lautenbach E, Bilker W, Matro J, Bell L, Dominguez T, et al. Risk factors for mediastinitis following median sternotomy in children. Pediatr Infect Dis J. 2007;26:613-8 pubmed
    b>Mediastinitis is a devastating complication of pediatric cardiothoracic surgery. However, risk factors for the development of mediastinitis are poorly characterized...
  5. Risnes I, Abdelnoor M, Almdahl S, Svennevig J. Mediastinitis after coronary artery bypass grafting risk factors and long-term survival. Ann Thorac Surg. 2010;89:1502-9 pubmed publisher
    b>Mediastinitis is a severe complication of coronary artery bypass grafting. The aim of the present study was to determine incidence of mediastinitis, its risk factors, and its effect on early and long-term survival.
  6. Deu Martín M, Saez Barba M, López Sanz I, Alcaraz Peñarrocha R, Romero Vielva L, Solé Montserrat J. [Mortality risk factors in descending necrotizing mediastinitis]. Arch Bronconeumol. 2010;46:182-7 pubmed publisher
    The term descending necrotizing mediastinitis (MND) refers to an infection that begins in the oropharyngeal region and spreads through the fascial planes into the mediastinum...
  7. Sarna T, Sengupta T, Miloro M, Kolokythas A. Cervical necrotizing fasciitis with descending mediastinitis: literature review and case report. J Oral Maxillofac Surg. 2012;70:1342-50 pubmed publisher
    ..Nevertheless, the progression of the disease to descending mediastinitis and septic shock leads to a poor prognosis and decreased survival...
  8. Gaudreau G, Costache V, Houde C, Cloutier D, Montalin L, Voisine P, et al. Recurrent sternal infection following treatment with negative pressure wound therapy and titanium transverse plate fixation. Eur J Cardiothorac Surg. 2010;37:888-92 pubmed publisher
  9. Skurnik D, Lasocki S, Bremont S, Muller Serieys C, Kitzis M, Courvalin P, et al. Development of ertapenem resistance in a patient with mediastinitis caused by Klebsiella pneumoniae producing an extended-spectrum beta-lactamase. J Med Microbiol. 2010;59:115-9 pubmed publisher
    ..pneumoniae isolate that had been selected in vivo by an ertapenem-containing regimen in a patient with mediastinitis despite high blood and mediastinal levels of ertapenem...
  10. Cho J, Kim Y, I H, Lee S, Jeong Y. Treatment of mediastinitis using video-assisted thoracoscopic surgery. Eur J Cardiothorac Surg. 2008;34:520-4 pubmed publisher
    b>Mediastinitis remains a life-threatening disease that is difficult to manage and has a poor prognosis...
  11. Sá M, Soares E, Santos C, Figueiredo O, Lima R, Escobar R, et al. Risk factors for mediastinitis after coronary artery bypass grafting surgery. Rev Bras Cir Cardiovasc. 2011;26:27-35 pubmed
    b>Mediastinitis is a serious complication of median sternotomy and is associated to significant morbidity and mortality...
  12. Karkas A, Chahine K, Schmerber S, Brichon P, Righini C. Optimal treatment of cervical necrotizing fasciitis associated with descending necrotizing mediastinitis. Br J Surg. 2010;97:609-15 pubmed publisher
    Cervical necrotizing fasciitis (CNF) associated with descending necrotizing mediastinitis (DNM) is a rapidly evolving and life-threatening condition...
  13. Kerneis S, Matta M, Hoï A, Podglajen I, Gutmann L, Novara A, et al. Postoperative mediastinitis due to Finegoldia magna with negative blood cultures. J Clin Microbiol. 2009;47:4180-2 pubmed publisher
    We report a case of Finegoldia magna (formerly known as Peptostreptococcus magnus) mediastinitis following coronary artery bypass in a 50-year-old patient...
  14. Chen K, Chen J, Kuo S, Huang P, Hsu H, Lee J, et al. Descending necrotizing mediastinitis: a 10-year surgical experience in a single institution. J Thorac Cardiovasc Surg. 2008;136:191-8 pubmed publisher
    ..and aggressive surgical drainage are very important for successful treatment of descending necrotizing mediastinitis. However, the surgical techniques used for this condition remain controversial...
  15. Sumi Y, Ogura H, Nakamori Y, Ukai I, Tasaki O, Kuwagata Y, et al. Nonoperative catheter management for cervical necrotizing fasciitis with and without descending necrotizing mediastinitis. Arch Otolaryngol Head Neck Surg. 2008;134:750-6 pubmed publisher
    To evaluate the clinical utility of catheter drainage for cervical necrotizing fasciitis (CNF) with and without descending necrotizing mediastinitis (DNM).
  16. Yamashiro T, Kamiya H, Murayama S, Unten S, Nakayama T, Gibo M, et al. Infectious mediastinitis after cardiovascular surgery: role of computed tomography. Radiat Med. 2008;26:343-7 pubmed publisher
    The aim of this study was to evaluate the effectiveness of computed tomography (CT) findings in the diagnosis of mediastinitis after cardiovascular surgery with median sternotomy.
  17. Singhal P, Kejriwal N, Lin Z, Tsutsui R, Ullal R. Optimal surgical management of descending necrotising mediastinitis: our experience and review of literature. Heart Lung Circ. 2008;17:124-8 pubmed
    Descending necrotising mediastinitis is a form of mediastinitis caused by odontogenic infection or deep cervical infections, which spreads to the mediastinum via the cervical fascial planes...
  18. Capdevila X, Jaber S, Pesonen P, Borgeat A, Eledjam J. Acute neck cellulitis and mediastinitis complicating a continuous interscalene block. Anesth Analg. 2008;107:1419-21 pubmed publisher
    We report a case of acute neck cellulitis and mediastinitis complicating a continuous interscalene brachial plexus block. A 61-yr-old man was scheduled for an elective arthroscopic right shoulder rotator cuff repair...
  19. Shah R, Chun R, Choi S. Mediastinitis in infants from deep neck space infections. Otolaryngol Head Neck Surg. 2009;140:936-8 pubmed publisher
    To describe mediastinitis in infants.
  20. Badiee P, Alborzi A, Farhoudi F. A case of Candida mediastinitis after dental extraction. J Infect Dev Ctries. 2011;5:75-8 pubmed
    Acute mediastinitis is a serious infection involving the connective mediastinal tissue in the interpleural spaces and other thoracic structures...
  21. Devaraj A, Griffin N, Nicholson A, Padley S. Computed tomography findings in fibrosing mediastinitis. Clin Radiol. 2007;62:781-6 pubmed
    To describe the CT features of fibrosing mediastinitis.
  22. Petzina R, Hoffmann J, Navasardyan A, Malmsjo M, Stamm C, Unbehaun A, et al. Negative pressure wound therapy for post-sternotomy mediastinitis reduces mortality rate and sternal re-infection rate compared to conventional treatment. Eur J Cardiothorac Surg. 2010;38:110-3 pubmed publisher
    Negative pressure wound therapy (NPWT) is a recently introduced treatment modality for post-sternotomy mediastinitis. The aim of this study was to compare the mortality rate, the sternal re-infection rate and the length of hospital stay ..
  23. Mekontso Dessap A, Vivier E, Girou E, Brun Buisson C, Kirsch M. Effect of time to onset on clinical features and prognosis of post-sternotomy mediastinitis. Clin Microbiol Infect. 2011;17:292-9 pubmed publisher
    ..However, its role in the setting of post-sternotomy mediastinitis (PSM) has not been specifically studied...
  24. Myers P, Khabiri E, Greub G, Kalangos A. Mycoplasma hominis mediastinitis after acute aortic dissection repair. Interact Cardiovasc Thorac Surg. 2010;11:857-8 pubmed publisher
    We report a case of ascending aortic graft infection by an atypical bacteria, Mycoplasma hominis, with mediastinitis, a dreaded complication after cardiac surgery...
  25. Steingrimsson S, Gottfredsson M, Kristinsson K, Gudbjartsson T. Deep sternal wound infections following open heart surgery in Iceland: a population-based study. Scand Cardiovasc J. 2008;42:208-13 pubmed publisher
    ..The aim of this nationwide case-control study was to study the epidemiology and identify risk factors of deep sternal wound infections (DSWI) in Iceland...
  26. Atkins B, Onaitis M, Hutcheson K, Kaye K, Petersen R, Wolfe W. Does method of sternal repair influence long-term outcome of postoperative mediastinitis?. Am J Surg. 2011;202:565-7 pubmed publisher
    Post-sternotomy mediastinitis reduces survival after cardiac surgery, potentially further affected by details of mediastinal vascularized flap reconstruction...
  27. Peikert T, Colby T, Midthun D, Pairolero P, Edell E, Schroeder D, et al. Fibrosing mediastinitis: clinical presentation, therapeutic outcomes, and adaptive immune response. Medicine (Baltimore). 2011;90:412-23 pubmed publisher
    Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum...
  28. Ridder G, Maier W, Kinzer S, Teszler C, Boedeker C, Pfeiffer J. Descending necrotizing mediastinitis: contemporary trends in etiology, diagnosis, management, and outcome. Ann Surg. 2010;251:528-34 pubmed publisher
    To evaluate contemporary trends in etiology, diagnosis, management, and outcome of descending necrotizing mediastinitis (DNM) and to draw the clinician's attention on this probably underappreciated disease.
  29. Ennker I, Malkoc A, Pietrowski D, Vogt P, Ennker J, Albert A. The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis--a single center experience with 54 patients. J Cardiothorac Surg. 2009;4:5 pubmed publisher
    Deep sternal infections, also known as poststernotomy mediastinitis, are a rare but often fatal complication in cardiac surgery...
  30. Dumaine A, Leveque N, Rosamel P, Tristan A, Raisky O, Obadia J, et al. [Enterovirus-related pericarditis and mediastinitis after heart surgery: a case report]. Ann Biol Clin (Paris). 2008;66:433-6 pubmed publisher
    We report a case of enterovirus related pericarditis associated to mediastinitis in a hospitalised 53-year-old male after heart surgery. Mediastinitis caused by enterovirus has not previously been described.
  31. Magedanz E, Bodanese L, Guaragna J, Albuquerque L, Martins V, Minossi S, et al. Risk score elaboration for mediastinitis after coronary artery bypass grafting. Rev Bras Cir Cardiovasc. 2010;25:154-9 pubmed
    The mediastinitis is a serious postoperative complication of cardiac surgery, with an incidence of 0.4 to 5% and mortality between 14 and 47%. Several models were proposed to assess risk of mediastinitis after cardiac surgery...
  32. Saiki Y, Kawamoto S, Sai S, Tabayashi K. An effective vacuum-assisted closure treatment for mediastinitis with aortic arch replacement. Interact Cardiovasc Thorac Surg. 2008;7:712-4 pubmed publisher
    ..We report our experience in the VAC therapy for patients with mediastinitis after aortic arch replacement. Between February 2003 and December 2006, five patients with a mean age of 72...
  33. Aerts J, Kloover J, Los J, van der Heijden O, Janssens A, Tournoy K. EUS-FNA of enlarged necrotic lymph nodes may cause infectious mediastinitis. J Thorac Oncol. 2008;3:1191-3 pubmed publisher
    ..Although EUS-FNA can be considered in general as a safe technique, complications do occur. We here report an infectious complication of EUS-FNA that occurred after puncture of a large malignant necrotic mediastinal lymph node...
  34. De Feo M, Vicchio M, Santè P, Cerasuolo F, Nappi G. Evolution in the treatment of mediastinitis: single-center experience. Asian Cardiovasc Thorac Ann. 2011;19:39-43 pubmed publisher
    ..In our experience, early surgical debridement and vacuum application followed by plastic reconstruction provided a satisfactory rate of healing and a good survival rate...
  35. Grauhan O, Navarsadyan A, Hussmann J, Hetzer R. Infectious erosion of aorta ascendens during vacuum-assisted therapy of mediastinitis. Interact Cardiovasc Thorac Surg. 2010;11:493-4 pubmed publisher
    ..patient with life-threatening bleeding due to infectious erosion of the aorta ascendens during VAC therapy of mediastinitis after cardiac surgery. To the best of our knowledge, this is the first reported case of infectious erosion (i...
  36. Elenbaas T, Soliman Hamad M, Schönberger J, Martens E, van Zundert A, van Straten A. Preoperative atrial fibrillation and elevated C-reactive protein levels as predictors of mediastinitis after coronary artery bypass grafting. Ann Thorac Surg. 2010;89:704-9 pubmed publisher
    b>Mediastinitis is a serious complication after coronary artery bypass grafting (CABG)...
  37. Ghafoori A, Twite M, Friesen R. Postoperative hyperglycemia is associated with mediastinitis following pediatric cardiac surgery. Paediatr Anaesth. 2008;18:1202-7 pubmed publisher
    b>Mediastinitis is an infrequent, but significant complication of median sternotomy. Perioperative hyperglycemia is associated with increased morbidity, including infection in pediatric and adult cardiac surgical patients...
  38. Barnea Y, Carmeli Y, Kuzmenko B, Navon Venezia S. Staphylococcus aureus mediastinitis and sternal osteomyelitis following median sternotomy in a rat model. J Antimicrob Chemother. 2008;62:1339-43 pubmed publisher
    ..We aimed to develop a new Staphylococcus aureus mediastinitis and sternal osteomyelitis model in rats that can be used to evaluate the efficacy of new antimicrobial ..
  39. Gualis J, Florez S, Tamayo E, Alvarez F, Castrodeza J, Castaño M. Risk factors for mediastinitis and endocarditis after cardiac surgery. Asian Cardiovasc Thorac Ann. 2009;17:612-6 pubmed publisher
    ..Patients diagnosed with mediastinitis or endocarditis during follow-up were compared with patients with no such infection...
  40. Athanassiadi K, Theakos N, Benakis G, Kakaris S, Skottis I. Omental transposition: the final solution for major sternal wound infection. Asian Cardiovasc Thorac Ann. 2007;15:200-3 pubmed
    ..Radical debridement along with omental flap transposition provides definitive control of the infection in cases of failure of other semi-conservative or surgical interventions. Prognosis depends on the general condition of the patient...
  41. Petzina R, Malmsjo M, Stamm C, Hetzer R. Major complications during negative pressure wound therapy in poststernotomy mediastinitis after cardiac surgery. J Thorac Cardiovasc Surg. 2010;140:1133-6 pubmed publisher
    Negative pressure wound therapy is the first-line treatment modality for poststernotomy mediastinitis in many heart centers...
  42. Weaver E, Nguyen X, Brooks M. Descending necrotising mediastinitis: two case reports and review of the literature. Eur Respir Rev. 2010;19:141-9 pubmed publisher
    Descending necrotising mediastinitis is a rare and serious infection with a high mortality rate, which complicates pharyngeal or odontogenic infection. Early recognition and treatment are essential in order to minimise morbidity...
  43. Weis F, Heyn J, Hinske C, Vogt F, Weis M, Kur F, et al. Daptomycin as supportive treatment option in patients developing mediastinitis after open cardiac surgery. J Cardiothorac Surg. 2012;7:81 pubmed publisher
    b>Mediastinitis is a severe complication after cardiac surgery. While improvement of prophylaxis and of medical and surgical therapy has reduced its incidence, the treatment of mediastinitis continues to be a challenging problem...
  44. Nina V, Assef M, Rodrigues R, Mendes V, Lages J, Amorim A, et al. Reconstruction of the chest wall with external metal brace: alternative technique in poststernotomy mediastinitis. Rev Bras Cir Cardiovasc. 2008;23:507-11 pubmed
    To demonstrate the experience with the reconstruction of the chest wall utilizing metal brace to reduce the tension in the suture lines of myocutaneous flap in cases of mediastinitis.
  45. Ennker I, Bär A, Florath I, Ennker J, Vogt P. In search of a standardized treatment for poststernotomy mediastinitis. Thorac Cardiovasc Surg. 2011;59:15-20 pubmed publisher
    Poststernotomy mediastinitis following median sternotomy procedures such as open heart surgery is a rare complication which nevertheless has a mortality rate of up to 50 %...
  46. Morisaki A, Hosono M, Sasaki Y, Hirai H, Sakaguchi M, Nakahira A, et al. Evaluation of risk factors for hospital mortality and current treatment for poststernotomy mediastinitis. Gen Thorac Cardiovasc Surg. 2011;59:261-7 pubmed publisher
    Poststernotomy mediastinitis (PSM) following cardiovascular surgery remains an intractable complication associated with considerable mortality...
  47. Eifert S, Kronschnabl S, Kaczmarek I, Reichart B, Vicol C. Omental flap for recurrent deep sternal wound infection and mediastinitis after cardiac surgery. Thorac Cardiovasc Surg. 2007;55:371-4 pubmed
    Unsuccessful surgical treatment of deep sternal wound infection (DSWI) and mediastinitis may lead to sepsis, multiorgan failure and death. Omental flap transposition (OFT) may, in this situation, be the only effective therapy.
  48. Wakahara T, Tanaka Y, Maniwa Y, Nishio W, Yoshimura M. Successful management of descending necrotizing mediastinitis. Asian Cardiovasc Thorac Ann. 2011;19:228-31 pubmed publisher
    Descending necrotizing mediastinitis is a critical infection and the mortality rate remains high. Early aggressive surgical drainage and antibiotic therapy are essential for treatment...
  49. Capecchi M, Buongiorno V, Romagnoli A, Parri S, Guiducci G, Bressan E. Severe descending mediastinitis after routine dental implant surgery: a case report. Eur J Oral Implantol. 2012;5:389-96 pubmed
    The aim of this article is to present a clinical case of severe descending mediastinitis following the insertion of three dental implants in the mandible.
  50. Inoue M, Nose N, Nishikawa H, Takahashi M, Zen Y, Kawaguchi M. Successful treatment of sclerosing mediastinitis with a high serum IgG4 level. Gen Thorac Cardiovasc Surg. 2007;55:431-3 pubmed
    Sclerosing mediastinitis is not a common condition in the thoracic cavity and is difficult to cure...
  51. Yamasaki Y, Nishi J, Nishikawa T, Tatsumoto C, Kasano F, Sano N, et al. Descending necrotizing mediastinitis secondary to retropharyngeal abscess in a child. J Infect Chemother. 2008;14:255-7 pubmed publisher
    We report herein of a 6-year-old boy with descending necrotizing mediastinitis (DNM) secondary to retropharyngeal abscess, who was successfully treated by the administration of antibiotics...
  52. Doddoli C, Trousse D, Avaro J, Djourno X, Giudicelli R, Fuentes P, et al. [Acute mediastinitis except in a context of cardiac surgery]. Rev Pneumol Clin. 2010;66:71-80 pubmed publisher
    Acute mediastinitis is a life-threatening complication (20 to 40 % of mortality) secondary to oropharyngeal abscesses, neck infections or oesophageal leak spreading into the mediastium...
  53. Eyileten Z, Akar A, Eryilmaz S, Sirlak M, Yazicioglu L, Durdu S, et al. Vacuum-assisted closure and bilateral pectoralis muscle flaps for different stages of mediastinitis after cardiac surgery. Surg Today. 2009;39:947-54 pubmed publisher
    To assess the results of bilateral pectoralis major muscle flaps (BPMMF) and vacuum-assisted closure (VAC) at different stages of postcardiac surgery mediastinitis.
  54. Athanassiadi K. Infections of the mediastinum. Thorac Surg Clin. 2009;19:37-45, vi pubmed publisher
    Infections of the mediastinum (ie, mediastinitis) are serious, are associated with high morbidity and mortality, and may result from adjacent disease with direct extension, hematogenous spread, or direct introduction into the mediastinal ..
  55. Ennker I, Pietrowski D, Vöhringer L, Kojcici B, Albert A, Vogt P, et al. Surgical debridement, vacuum therapy and pectoralis plasty in poststernotomy mediastinitis. J Plast Reconstr Aesthet Surg. 2009;62:1479-83 pubmed publisher
    In cardiac surgery poststernotomy mediastinitis continues to be a serious cause of morbidity and mortality. We report our experience with vacuum-assisted closure (VAC) therapy followed by reconstruction with M...
  56. Park H, Hickman N, Freund F, Skaryak L, Fishel R. Methicillin resistant Staphylococcus aureus infection in descending necrotizing mediastinitis from retropharyngeal perforation: a rare event. J Wound Ostomy Continence Nurs. 2010;37:209-13 pubmed publisher
    Descending necrotizing mediastinitis is a rare but serious infection of the interpleural spaces and mediastinal connective tissue from the cervical region to the diaphragm that spreads rapidly along fascial planes.
  57. Suzuki H, Koh E, Hoshino I, Kishi H, Saitoh Y. Mediastinal teratoma complicated with acute mediastinitis. Gen Thorac Cardiovasc Surg. 2010;58:105-8 pubmed publisher
    We report a case of a mediastinal teratoma associated with acute mediastinitis that required an emergency operation. These tumors cause a variety of complications, but reports of acute mediastinitis are rare...