voice disorders


Summary: Pathological processes that affect voice production, usually involving VOCAL CORDS and the LARYNGEAL MUCOSA. Voice disorders can be caused by organic (anatomical), or functional (emotional or psychological) factors leading to DYSPHONIA; APHONIA; and defects in VOICE QUALITY, loudness, and pitch.

Top Publications

  1. Remmelts A, Hoebers F, Klop W, Balm A, Hamming Vrieze O, Van Den Brekel M. Evaluation of lasersurgery and radiotherapy as treatment modalities in early stage laryngeal carcinoma: tumour outcome and quality of voice. Eur Arch Otorhinolaryngol. 2013;270:2079-87 pubmed publisher
    ..Depth of laser resection is of influence on voice deficiency displayed by a significantly higher percentage of voice deficiency in patients treated with laser surgery for T1b lesions. ..
  2. Manfredi C, Giordano A, Schoentgen J, Fraj S, Bocchi L, Dejonckere P. Validity of jitter measures in non-quasi-periodic voices. Part II: the effect of noise. Logoped Phoniatr Vocol. 2011;36:78-89 pubmed publisher
    ..Hence, the use of a robust tool for voice analysis can give valid support to clinicians in term of reliability, reproducibility of results, and time-saving. ..
  3. Rusz J, Cmejla R, Ruzickova H, Ruzicka E. Quantitative acoustic measurements for characterization of speech and voice disorders in early untreated Parkinson's disease. J Acoust Soc Am. 2011;129:350-67 pubmed publisher
    ..The speech defects thus uncovered differ individually in various characteristics including phonation, articulation, and prosody. ..
  4. Verdolini K, Min Y, Titze I, Lemke J, Brown K, van Mersbergen M, et al. Biological mechanisms underlying voice changes due to dehydration. J Speech Lang Hear Res. 2002;45:268-81 pubmed
    ..In contrast, no evidence was seen that DH accomplished either secretory dehydration or PTP shifts. The results indicate that systemic dehydration can mediate PTP increases. The influence of secretory dehydration on PTP is unclear. ..
  5. Jacobi I, van der Molen L, Huiskens H, van Rossum M, Hilgers F. Voice and speech outcomes of chemoradiation for advanced head and neck cancer: a systematic review. Eur Arch Otorhinolaryngol. 2010;267:1495-505 pubmed publisher
  6. Cohen S, Garrett C, Dupont W, Ossoff R, Courey M. Voice-related quality of life in T1 glottic cancer: irradiation versus endoscopic excision. Ann Otol Rhinol Laryngol. 2006;115:581-6 pubmed
    ..The posttreatment VHI scores were similar for the EBRT- and CLE-treated patients (p = .1, Wilcoxon rank sum test). We conclude that CLE and EBRT provide comparable levels of voice handicap for patients with T1 glottic cancer. ..
  7. Sliwinska Kowalska M, Niebudek Bogusz E, Fiszer M, Los Spychalska T, Kotylo P, Sznurowska Przygocka B, et al. The prevalence and risk factors for occupational voice disorders in teachers. Folia Phoniatr Logop. 2006;58:85-101 pubmed
    Occupational voice disorders in Poland account for over 25% of all occupational diseases...
  8. Rehder M, Behlau M. Perceptual, auditory and acoustic vocal analysis of speech and singing in choir conductors. Pro Fono. 2008;20:195-200 pubmed
    ..the voice of choir conductors is adapted, presenting fewer deviations in the singing voice when compared to the speaking voice. Productions differ based the voice modality, singing or speaking. ..
  9. Brown D, Hilgers F, Irish J, Balm A. Postlaryngectomy voice rehabilitation: state of the art at the millennium. World J Surg. 2003;27:824-31 pubmed

More Information


  1. Duffy O, Hazlett D. The impact of preventive voice care programs for training teachers: a longitudinal study. J Voice. 2004;18:63-70 pubmed
    ..The findings of this study will be of benefit to teachers, their educators, voice therapists, health promoters, and human resource personnel. ..
  2. Bruno E, de Padova A, Napolitano B, Marroni P, Batelli R, Ottaviani F, et al. Voice disorders and posturography: variables to define the success of rehabilitative treatment. J Voice. 2009;23:71-5 pubmed
    ..to study the postural pattern during voice production in healthy subjects compared with patients affected by voice disorders and in the same patients before and after vocal treatment by means of static posturography...
  3. Connor N, Suzuki T, Lee K, Sewall G, Heisey D. Neuromuscular junction changes in aged rat thyroarytenoid muscle. Ann Otol Rhinol Laryngol. 2002;111:579-86 pubmed
    ..The results of this study increase our understanding of the age-related morphological changes in the larynx, and may serve as a baseline to test the effectiveness of future interventions...
  4. Wedman J, Heimdal J, Elstad I, Olofsson J. Voice results in patients with T1a glottic cancer treated by radiotherapy or endoscopic measures. Eur Arch Otorhinolaryngol. 2002;259:547-50 pubmed
    ..Therefore, the post-treatment voice quality is not a reason to favour radiotherapy for small T1a glottic squamous cell cancers without involvement of the anterior commissure...
  5. Moerman M, Martens J, Dejonckere P. Application of the Voice Handicap Index in 45 patients with substitution voicing after total laryngectomy. Eur Arch Otorhinolaryngol. 2004;261:423-8 pubmed
    ..It seems that the E domain is overstated due to the number of problematic items in the P and F domains. ..
  6. Godino Llorente J, Gómez Vilda P. Automatic detection of voice impairments by means of short-term cepstral parameters and neural network based detectors. IEEE Trans Biomed Eng. 2004;51:380-4 pubmed
    ..the present paper two neural-network based classification approaches applied to the automatic detection of voice disorders will be studied...
  7. Ferreira L, de Oliveira Latorre M, Pinto Giannini S, de Assis Moura Ghirardi A, de Fraga e Karmann D, Silva E, et al. Influence of abusive vocal habits, hydration, mastication, and sleep in the occurrence of vocal symptoms in teachers. J Voice. 2010;24:86-92 pubmed publisher
    ..However, the findings in the present study show the need to further focus on lifestyle habits related to sleep and eating habits. ..
  8. Vilkman E. Occupational safety and health aspects of voice and speech professions. Folia Phoniatr Logop. 2004;56:220-53 pubmed
    ..In professions with heavy vocal loading (e.g. school and kindergarten teachers), occupational voice disorders threatening working ability are common...
  9. Roy N, Merrill R, Thibeault S, Gray S, Smith E. Voice disorders in teachers and the general population: effects on work performance, attendance, and future career choices. J Speech Lang Hear Res. 2004;47:542-51 pubmed
    To examine the frequency and adverse effects of voice disorders on job performance and attendance in teachers and the general population, 2,401 participants from Iowa and Utah (n1 = 1,243 teachers and n2 = 1,279 nonteachers) were ..
  10. Duan J, Zhu L, Yan Y, Pan T, Lu P, Ma F. The efficacy of a voice training program: a case-control study in China. Eur Arch Otorhinolaryngol. 2010;267:101-5 pubmed publisher
    ..So we conclude that the voice training program is suitable to treat voice diseases, particularly for middle school teachers. This result provided reliable evidence for carrying out further voice training in China. ..
  11. Angsuwarangsee T, Morrison M. Extrinsic laryngeal muscular tension in patients with voice disorders. J Voice. 2002;16:333-43 pubmed
    ..muscles can yield important information about internal laryngeal postures and diagnosis of muscle misuse voice disorders, particularly MMD type 3 (anteroposterior supraglottic compression)...
  12. Kooijman P, Thomas G, Graamans K, de Jong F. Psychosocial impact of the teacher's voice throughout the career. J Voice. 2007;21:316-24 pubmed
  13. Meyer T. The larynx for neurologists. Neurologist. 2009;15:313-8 pubmed publisher
    ..Understanding laryngeal function will promote earlier diagnosis of neurologic deficits and facilitate accurate evaluation and treatment of laryngeal dysfunction. ..
  14. Ortega J, Cassinello N, Dorcaratto D, Leopaldi E. Computerized acoustic voice analysis and subjective scaled evaluation of the voice can avoid the need for laryngoscopy after thyroid surgery. Surgery. 2009;145:265-71 pubmed publisher
    ..After thyroid surgery, vocal cord palsy may be suspected when there is an alteration in GIRBAS scale or in several parameters of the CAVA. Laryngoscopy may only be necessary when the CAVA and SSEV are abnormal. ..
  15. Carrara de Angelis E, Feher O, Barros A, Nishimoto I, Kowalski L. Voice and swallowing in patients enrolled in a larynx preservation trial. Arch Otolaryngol Head Neck Surg. 2003;129:733-8 pubmed
    ..Laryngeal preservation resulted in voice and swallowing abnormalities, but they tend to be mild to moderate, allowing intelligible communication and efficient swallowing in most patients. ..
  16. Lombardi C, Raffaelli M, D Alatri L, Marchese M, Rigante M, Paludetti G, et al. Voice and swallowing changes after thyroidectomy in patients without inferior laryngeal nerve injuries. Surgery. 2006;140:1026-32; discussion 1032-4 pubmed
    ..5, respectively; P < .05). Physicians should inform patients that transient voice and swallowing symptoms may occur following total thyroidectomy, and our data suggest mild symptoms may occur in the majority of operated patients. ..
  17. Moerman M, Pieters G, Martens J, Van der Borgt M, Dejonckere P. Objective evaluation of the quality of substitution voices. Eur Arch Otorhinolaryngol. 2004;261:541-7 pubmed
    ..Correlations between the objective parameters and the perceptual parameters are moderate. ..
  18. Behlau M, Hogikyan N, Gasparini G. Quality of life and voice: study of a Brazilian population using the voice-related quality of life measure. Folia Phoniatr Logop. 2007;59:286-96 pubmed
    ..The relationship between self-assessment of voice quality and V-RQOL scores was very clear and statistically significant, especially when considering the group with a known voice disorder. ..
  19. Pasa G, Oates J, Dacakis G. The relative effectiveness of vocal hygiene training and vocal function exercises in preventing voice disorders in primary school teachers. Logoped Phoniatr Vocol. 2007;32:128-40 pubmed
    b>Voice disorders in teachers have a significant impact on their occupational functioning and well being...
  20. Haslinger B, Erhard P, Dresel C, Castrop F, Roettinger M, Ceballos Baumann A. "Silent event-related" fMRI reveals reduced sensorimotor activation in laryngeal dystonia. Neurology. 2005;65:1562-9 pubmed
    ..To study with fMRI the pattern of sensorimotor activation in patients with spasmodic dysphonia (laryngeal dystonia) compared to healthy controls...
  21. Bovo R, Galceran M, Petruccelli J, Hatzopoulos S. Vocal problems among teachers: evaluation of a preventive voice program. J Voice. 2007;21:705-22 pubmed
    ..of two lectures, a short group voice therapy, home-controlled voice exercises, and hygiene, represents a feasible and cost-effective primary prevention of voice disorders in a homogeneous and well-motivated population of teachers.
  22. Moerman M, Martens J, Crevier Buchman L, de Haan E, Grand S, Tessier C, et al. The INFVo perceptual rating scale for substitution voicing: development and reliability. Eur Arch Otorhinolaryngol. 2006;263:435-9 pubmed
    ..Our experiments demonstrate that the INFVo rating scale has good potential to become a routine perceptual evaluation method in a multidimensional assessment protocol for substitution voicing. ..
  23. Kasama S, Brasolotto A. [Vocal perception and life quality]. Pro Fono. 2007;19:19-28 pubmed
    ..A relationship between the life quality of the dysphonic individual and the vocal perception of listeners was not observed. ..
  24. Leeper H, Parsa V, Jamieson D, Heeneman H. Acoustical aspects of vocal function following radiotherapy for early T1a laryngeal cancer. J Voice. 2002;16:289-302 pubmed
    ..Future research evaluating vowel type and acoustic perturbation measures with a larger sample of subjects over a longer time period seems warranted. ..
  25. de Jong F, Kooijman P, Thomas G, Huinck W, Graamans K, Schutte H. Epidemiology of voice problems in Dutch teachers. Folia Phoniatr Logop. 2006;58:186-98 pubmed
    ..Furthermore, this study indicates the importance of voice care not only during training for the profession but also during the career. ..
  26. Tavares E, Martins R. Vocal evaluation in teachers with or without symptoms. J Voice. 2007;21:407-14 pubmed
  27. Maertens K, de Jong F. The voice handicap index as a tool for assessment of the biopsychosocial impact of voice problems. B-ENT. 2007;3:61-6 pubmed
    ..To investigate if the VHI can monitor biopsychosocial impact of voice disorders and to provide a frame of reference for use of the VHI in general ENT practice...
  28. Potter N. Voice disorders in children with classic galactosemia. J Inherit Metab Dis. 2011;34:377-85 pubmed publisher
    ..b>Voice disorders due to laryngeal insufficiency were common in children with dysarthria and co-occurred with CAS...
  29. Eckel E, Glanz H, Hess M, Nawka T, Schultz Coulon H. [Phoniatry and ENT on: dagnostic and therapeutic problems with organic voice disorders]. Laryngorhinootologie. 2003;82:756-7 pubmed
  30. Loughran S, Calder N, MacGregor F, Carding P, MacKenzie K. Quality of life and voice following endoscopic resection or radiotherapy for early glottic cancer. Clin Otolaryngol. 2005;30:42-7 pubmed
  31. Schuster M, Lohscheller J, Kummer P, Hoppe U, Eysholdt U, Rosanowski F. Quality of life in laryngectomees after prosthetic voice restoration. Folia Phoniatr Logop. 2003;55:211-9 pubmed
    ..The SF-36 is a suitable instrument for quality of life assessment in order to define disease-dependent and individual limitations of quality of life in laryngectomees and should lead to individual interventions. ..
  32. Spina A, Maunsell R, Sandalo K, Gusmão R, Crespo A. Correlation between voice and life quality and occupation. Braz J Otorhinolaryngol. 2009;75:275-9 pubmed
    ..It is common knowledge amongst professionals involved with the treatment of voice disorders the need for objective protocols to evaluate voice quality and measure its impact on the individual's quality ..
  33. Friedrich G, Dejonckere P. [The voice evaluation protocol of the European Laryngological Society (ELS) -- first results of a multicenter study]. Laryngorhinootologie. 2005;84:744-52 pubmed
    ..Results obtained in 94 patients with benign voice disorders were evaluated retrospectively in a multicenter study...
  34. Boutsen F, Cannito M, Taylor M, Bender B. Botox treatment in adductor spasmodic dysphonia: a meta-analysis. J Speech Lang Hear Res. 2002;45:469-81 pubmed
    ..This result, together with methodological limitations and lack of standardization in BT efficacy research, justifies caution when making inferences regarding BT treatment benefit in adductor spasmodic dysphonia...
  35. Karnell M, Melton S, Childes J, Coleman T, Dailey S, Hoffman H. Reliability of clinician-based (GRBAS and CAPE-V) and patient-based (V-RQOL and IPVI) documentation of voice disorders. J Voice. 2007;21:576-90 pubmed
    ..males and 61 females performed by a certified speech-language pathologist specializing in the assessment of voice disorders. In addition, two patient-based scales (Voice Related Quality of Life, or V-RQOL, and Iowa Patient's Voice ..
  36. Lifante J, McGill J, Murry T, Aviv J, Inabnet W. A prospective, randomized trial of nerve monitoring of the external branch of the superior laryngeal nerve during thyroidectomy under local/regional anesthesia and IV sedation. Surgery. 2009;146:1167-73 pubmed publisher
    ..Nerve monitoring aids in the visualization of the EBSLN during mini-incision thyroidectomy under local/regional anesthesia and leads to an improvement in patient-assessed voice quality after surgery but does not impact swallowing. ..
  37. Gasparini G, Behlau M. Quality of life: validation of the Brazilian version of the voice-related quality of life (V-RQOL) measure. J Voice. 2009;23:76-81 pubmed
    ..026; Social-Emotional 0.006; and Total 0.008). The study concluded that the Brazilian version of the V-RQOL is valid, reliable, and responsive to change and it can play an important role in the dysphonic patient's voice evaluation. ..
  38. Solomon N, Glaze L, Arnold R, van Mersbergen M. Effects of a vocally fatiguing task and systemic hydration on men's voices. J Voice. 2003;17:31-46 pubmed
    b>Voice disorders, specifically vocal fatigue, are more commonly reported by women than by men. Previously, 4 women with normal untrained voices read loudly for 2 hours in an attempt to fatigue the voice...
  39. Ilomaki I, Laukkanen A, Leppanen K, Vilkman E. Effects of voice training and voice hygiene education on acoustic and perceptual speech parameters and self-reported vocal well-being in female teachers. Logoped Phoniatr Vocol. 2008;33:83-92 pubmed publisher
    ..Both groups equally self-reported increase of voice care knowledge. Results seem to indicate improved vocal well-being after training. ..
  40. McHenry M, Carlson H. The vocal health of auctioneers. Logoped Phoniatr Vocol. 2004;29:41-7 pubmed
    ..In addition, the duration of auctioning without a break significantly contributed to vocal fatigue. Vocal hygiene recommendations are provided based on these findings. ..
  41. Williams N. Occupational groups at risk of voice disorders: a review of the literature. Occup Med (Lond). 2003;53:456-60 pubmed
    ..A number of studies have identified certain occupational groups at increased risk of developing occupational voice disorders, namely teachers, singers and aerobics instructors...
  42. Kazi R, Venkitaraman R, Johnson C, Prasad V, Clarke P, Rhys Evans P, et al. Electroglottographic comparison of voice outcomes in patients with advanced laryngopharyngeal cancer treated by chemoradiotherapy or total laryngectomy. Int J Radiat Oncol Biol Phys. 2008;70:344-52 pubmed
    ..This prospective study demonstrates significantly better outcome for patients treated with chemoradiotherapy as compared with TL. Progressive normalization of many voice parameters occurs over the 12 months following chemoradiotherapy. ..
  43. Preciado López J, Pérez Fernández C, Calzada Uriondo M, Preciado Ruiz P. Epidemiological study of voice disorders among teaching professionals of La Rioja, Spain. J Voice. 2008;22:489-508 pubmed
    The purpose of the present study was to calculate the prevalence and incidence of voice disorders among teaching staff and find out the associated occupational risk factors...
  44. Svec J, Sram F, Schutte H. Videokymography in voice disorders: what to look for?. Ann Otol Rhinol Laryngol. 2007;116:172-80 pubmed
    ..features to enable systematic visual characterization and categorization of vocal fold vibratory patterns in voice disorders. A cross-sectional, descriptive design was used...
  45. Blitzer A. Botulinum toxin A and B: a comparative dosing study for spasmodic dysphonia. Otolaryngol Head Neck Surg. 2005;133:836-8 pubmed
    ..This study shows that a conversion factor of 52.3:1 Myobloc (BTX-B) to Botox (BTX-A) and that Myobloc is an effective alternative to Botox (BTX-A) for patients with spasmodic dysphonia. ..
  46. Deary I, Wilson J, Carding P, Mackenzie K. VoiSS: a patient-derived Voice Symptom Scale. J Psychosom Res. 2003;54:483-9 pubmed
    ..The VoiSS is simple for patients to complete and easy to score. It is sensitive enough to reflect the wide range of communication, physical symptoms and emotional responses implicit in adult dysphonia. ..
  47. Ruotsalainen J, Sellman J, Lehto L, Verbeek J. Systematic review of the treatment of functional dysphonia and prevention of voice disorders. Otolaryngol Head Neck Surg. 2008;138:557-65 pubmed publisher
    To evaluate the effectiveness of interventions for treating functional dysphonia or preventing voice disorders in adults...
  48. Cantarella G, Berlusconi A, Maraschi B, Ghio A, Barbieri S. Botulinum toxin injection and airflow stability in spasmodic dysphonia. Otolaryngol Head Neck Surg. 2006;134:419-23 pubmed
    ..A reduced airflow CV probably does not depend solely on increased airflow due to thyroarytenoid muscle paresis, and may indicate a change in laryngeal motoneuronal activity. B-3b. ..
  49. van Gogh C, Verdonck de Leeuw I, Boon Kamma B, Rinkel R, de Bruin M, Langendijk J, et al. The efficacy of voice therapy in patients after treatment for early glottic carcinoma. Cancer. 2006;106:95-105 pubmed
    ..Voice therapy proved to be effective in patients who had voice problems after treatment for early glottic carcinoma. Improvement not only was noticed by the patients (VHI) but also was confirmed by objective voice parameters. ..
  50. Stojadinovic A, Shaha A, Orlikoff R, Nissan A, Kornak M, Singh B, et al. Prospective functional voice assessment in patients undergoing thyroid surgery. Ann Surg. 2002;236:823-32 pubmed
    ..Factors other than laryngeal nerve injury appear to alter post-thyroidectomy voice. The variability of patient symptoms underscores the importance of understanding the physiology of dysphonia. ..
  51. Miller N, Noble E, Jones D, Burn D. Life with communication changes in Parkinson's disease. Age Ageing. 2006;35:235-9 pubmed
    ..The role of early referral to speech and language therapy is therefore worthy of detailed investigation. ..
  52. Tamura E, Kitahara S, Ogura M, Kohno N. Voice quality after laser surgery or radiotherapy for T1a glottic carcinoma. Laryngoscope. 2003;113:910-4 pubmed
    ..The average fundamental frequency is higher than normal after laser surgery, but the effect on the quality of life was trivial. ..
  53. Bielamowicz S, Stager S, Badillo A, Godlewski A. Unilateral versus bilateral injections of botulinum toxin in patients with adductor spasmodic dysphonia. J Voice. 2002;16:117-23 pubmed
    ..012) than successive bilateral injections to produce the same or longer duration of benefit. We conclude that a unilateral injection routine has a more optimal and consistent treatment effect/side effect profile. ..