Summary: Inflammation of the lung parenchyma that is associated with BRONCHITIS, usually involving lobular areas from TERMINAL BRONCHIOLES to the PULMONARY ALVEOLI. The affected areas become filled with exudate that forms consolidated patches.

Top Publications

  1. Bednarek D, Zdzisinska B, Kondracki M, Kandefer Szerszen M. Effect of steroidal and non-steroidal anti-inflammatory drugs in combination with long-acting oxytetracycline on non-specific immunity of calves suffering from enzootic bronchopneumonia. Vet Microbiol. 2003;96:53-67 pubmed
    ..combination with oxytetracycline on clinical and immunological parameters of calves suffering from enzootic bronchopneumonia. The study was performed on 30 Black-and-White Lowland Breed calves with clinical signs of enzootic ..
  2. Hewson J, Viel L, Caswell J, Shewen P, Buchanan Smith J. Impact of isoflupredone acetate treatment on clinical signs and weight gain in weanling heifers with experimentally induced Mannheimia haemolytica bronchopneumonia. Am J Vet Res. 2011;72:1613-21 pubmed publisher
    ..To characterize the impact of Mannheimia haemolytica infection on feed intake and weight gain in feedlot heifers and to evaluate the clinical efficacy of isoflupredone acetate administered in combination with oxytetracycline...
  3. Meijer W, Prescott J. Rhodococcus equi. Vet Res. 2004;35:383-96 pubmed
    Rhodococcus equi is an important cause of subacute or chronic abscessating bronchopneumonia of foals up to 3-5 months of age...
  4. Jounblat R, Kadioglu A, Mitchell T, Andrew P. Pneumococcal behavior and host responses during bronchopneumonia are affected differently by the cytolytic and complement-activating activities of pneumolysin. Infect Immun. 2003;71:1813-9 pubmed
    ..all clinical isolates of Streptococcus pneumoniae, is strongly implicated in the pathogenesis of pneumococcal bronchopneumonia and septicemia...
  5. Sheehan M, Cassidy J, Brady J, Ball H, Doherty M, Quinn P, et al. An aetiopathological study of chronic bronchopneumonia in lambs in Ireland. Vet J. 2007;173:630-7 pubmed
    Chronic bronchopneumonia in lambs, also known as 'atypical' or 'chronic, non-progressive' pneumonia is a common, frequently sub-clinical disease affecting animals under 12-months-old in intensive production systems...
  6. Li M, Harkema J, Cuff C, Pestka J. Deoxynivalenol exacerbates viral bronchopneumonia induced by respiratory reovirus infection. Toxicol Sci. 2007;95:412-26 pubmed
    ..Respiratory reovirus infection caused a mild bronchopneumonia in mice which was markedly exacerbated by DON as evidenced by severe inflammatory cell infiltration, marked ..
  7. Centeno M, Rivera F, Cerva L, Tsutsumi V, Gallegos E, Calderon A, et al. Hartmannella vermiformis isolated from the cerebrospinal fluid of a young male patient with meningoencephalitis and bronchopneumonia. Arch Med Res. 1996;27:579-86 pubmed
    Meningoencephalitis and bronchopneumonia were documented in a patient from Peubla, Mexico...
  8. Suzuki K, Yamaya Y, Kanzawa N, Chiba M, Sera K, Asano R. Trace and major elements status in bronchoalveolar lavage fluid in dogs with or without bronchopneumonia. Biol Trace Elem Res. 2008;124:92-6 pubmed publisher
    The aim of this study was to investigate the relationships between the bronchopneumonia and mean concentrations of those trace elements in bronchoalveolar lavage fluid (BALF)...
  9. Klekner A, Bagyi K, Bognar L, Gaspar A, Andrasi M, Szabo J. Effectiveness of cephalosporins in the sputum of patients with nosocomial bronchopneumonia. J Clin Microbiol. 2006;44:3418-21 pubmed
    Nosocomial bronchopneumonia is a frequent complication in patients with chronic intratracheal intubation...

More Information


  1. Tullio V, Mandras N, Banche G, Allizond V, Gaido E, Roana J, et al. Schizophyllum commune: an unusual of agent bronchopneumonia in an immunocompromised patient. Med Mycol. 2008;46:735-8 pubmed publisher
    We report a case of bronchopneumonia due to Schizophyllum commune in an immunocompromised patient. While this fungus rarely causes disease in humans, it has been reported in association with several clinical entities and lung disorders...
  2. Shmuely H, Pitlik S, Inbal A, Rosenfeld J. Pelger-Huët anomaly mimicking 'shift to the left'. Neth J Med. 1993;42:168-70 pubmed
  3. Oyarzun M, Dussaubat N, Gonzalez S. Effect of 0.25 ppm ozone exposure on pulmonary damage induced by bleomycin. Biol Res. 2005;38:353-8 pubmed
    ..06). Frequency of bronchopneumonia increased from 1/7 to 6/6 (p <0...
  4. Canton R, Cobos N, de Gracia J, Baquero F, Honorato J, Gartner S, et al. Antimicrobial therapy for pulmonary pathogenic colonisation and infection by Pseudomonas aeruginosa in cystic fibrosis patients. Clin Microbiol Infect. 2005;11:690-703 pubmed
    ..If multiresistant P. aeruginosa is isolated, antimicrobial agents that retain activity are recommended and epidemiological control measures should be established. ..
  5. Loneragan G, Gould D, Mason G, Garry F, Yost G, Miles D, et al. Involvement of microbial respiratory pathogens in acute interstitial pneumonia in feedlot cattle. Am J Vet Res. 2001;62:1519-24 pubmed
    ..Histologic diagnoses were categorized for AIP, bronchopneumonia (BP), control samples (no evidence of disease), and other disorders...
  6. De Simone C, Di Fabio S, Moretti S, Tzantzoglou S, Trinchieri V, Gargiulo M. Open randomized controlled parallel study of ofloxacin versus trimethoprim-sulfamethoxazole treatment of lower respiratory tract and urinary infections. Chemotherapy. 1991;37 Suppl 1:39-48 pubmed
    ..The measurement of serum and intracellular (polymorphonuclear cells and lymphocytes) levels of OFX and TMP-SMX and the assessment of the host's immunocompetence ruled out the possibility of any immunotoxicological side effect...
  7. Wei H, Tan B, Yang L, Deng N. [Antibiotic resistance of gram-negative Bacillis isolated from children with bronchopneumonia]. Zhongguo Dang Dai Er Ke Za Zhi. 2011;13:20-2 pubmed
    To study the distribution and antibiotic resistance of gram-negative pathogens isolated from children with bronchopneumonia. The distribution and the results of susceptibility tests of 272 strains of gram-negative Bacillis isolated from ..
  8. Meqdam M, Subaih S. Rapid detection and clinical features of infants and young children with acute lower respiratory tract infection due to respiratory syncytial virus. FEMS Immunol Med Microbiol. 2006;47:129-33 pubmed
    ..The most positive specimens came from patients less than one year old (51.3%), and were associated with bronchopneumonia (56.7%) or bronchiolits (55.4%)...
  9. Shepherd C, Gomez M, Lie J, Crowson C. Causes of death in patients with tuberous sclerosis. Mayo Clin Proc. 1991;66:792-6 pubmed
    ..Thirteen patients with severe mental handicaps died of either status epilepticus or bronchopneumonia; in all but one of these patients, the only source of information was the death certificate...
  10. Hsieh C, Chao A, Chang Y, Kuo D, Hsieh T, Hung H. Outcome of congenital cystic adenomatoid malformation of the lung after antenatal diagnosis. Int J Gynaecol Obstet. 2005;89:99-102 pubmed
    ..With conservative postnatal management, seven neonates had no major complications and one developed bronchopneumonia. Taken together, the findings of the present study and a review of the literature strongly support the ..
  11. Kodama M, Kodama T, Murakami M. The value of the dehydroepiandrosterone-annexed vitamin C infusion treatment in the clinical control of chronic fatigue syndrome (CFS). I. A Pilot study of the new vitamin C infusion treatment with a volunteer CFS patient. In Vivo. 1996;10:575-84 pubmed
    ..The significance of parallelism between pulmonary infection and CFS, as observed in the clinical course of the test subject, was discussed in the light of the focal infection theory of nephritis. ..
  12. Breccia M, Andriani A, Montanaro M, Abruzzese E, Buccisano F, Cedrone M, et al. Ruxolitinib in clinical practice for primary and secondary myelofibrosis: an analysis of safety and efficacy of Gruppo Laziale of Ph-negative MPN. Ann Hematol. 2017;96:387-391 pubmed publisher
    ..7%), thrombocytopenia (25.5%), infections (16.3%, of which 10 were bronchopneumonia), fluid retention (3%), diarrhea (2%) and abdominal pain (2%)...
  13. Rutenberg D, Venner M, Giguere S. Efficacy of Tulathromycin for the Treatment of Foals with Mild to Moderate Bronchopneumonia. J Vet Intern Med. 2017;31:901-906 pubmed publisher
    There is conflicting data regarding the efficacy of tulathromycin for the treatment of foals with bronchopneumonia. Tulathromycin is effective for the treatment of bronchopneumonia in foals and noninferior to the combination of ..
  14. Baum B, Hewicker Trautwein M, Wohlsein P. Multifocal pleural cystic squamous metaplasia in a horse with chronic obstructive bronchopneumonia. Vet Pathol. 2004;41:532-4 pubmed
    ..In addition, caudal lung lobes were severely affected by a chronic partially obliterative bronchiolitis and peribronchiolitis with multifocal pleural involvement. ..
  15. Yanagihara K, Seki M, Cheng P. Lipopolysaccharide Induces Mucus Cell Metaplasia in Mouse Lung. Am J Respir Cell Mol Biol. 2001;24:66-73 pubmed
    ..In addition, C2GnT-M may serve as a marker for mucus cells in mouse lung. This LPS-induced mucus cell metaplasia and hyperplasia model should be useful for the study of Pseudomonas-induced airway mucus hypersecretory diseases. ..
  16. Kukavica Ibrulj I, Bragonzi A, Paroni M, Winstanley C, Sanschagrin F, O Toole G, et al. In vivo growth of Pseudomonas aeruginosa strains PAO1 and PA14 and the hypervirulent strain LESB58 in a rat model of chronic lung infection. J Bacteriol. 2008;190:2804-13 pubmed publisher
    ..These differences were further confirmed with biofilm and motility in vitro assays, where strain LESB58 produced more biofilm but had less capacity for motility than PAO1 and PA14...
  17. Klotzbach H, von den Driesch P, Schulz F. [Peri-mortem skin lesions caused by regurgitation of gastric juice. 2 case reports and differential diagnostic considerations]. Arch Kriminol. 2003;212:30-40 pubmed
  18. Brown A, Beatty J, Nicoll R, Knight T, Krockenberger M, Barrs V. Dyspnoea and pulmonary consolidation in a cat with T-cell lymphoma. J Feline Med Surg. 2011;13:772-5 pubmed publisher
    ..This unusual presentation serves to alert practitioners to the possibility of lymphoma as a cause of severe bronchopulmonary disease in the cat. ..
  19. Gilliland M. Frequency of bronchopneumonia in children with survival interval before death. Am J Forensic Med Pathol. 2001;22:200-2 pubmed
    ..Some survive varying intervals and are found to have bronchopneumonia at death...
  20. Ali Z, Levine B, Ripple M, Fowler D. Diabetic ketoacidosis: a silent death. Am J Forensic Med Pathol. 2012;33:189-93 pubmed publisher
  21. Subramoni S, Nguyen D, Sokol P. Burkholderia cenocepacia ShvR-regulated genes that influence colony morphology, biofilm formation, and virulence. Infect Immun. 2011;79:2984-97 pubmed publisher
    ..Together, our data show that the ShvR-regulated genes BCAS0208 to BCAS0201 are required for the rough colony morphotype, biofilm and pellicle formation, and virulence in B. cenocepacia...
  22. Muscatello G. Rhodococcus equi pneumonia in the foal--part 2: diagnostics, treatment and disease management. Vet J. 2012;192:27-33 pubmed publisher
    ..Effective management of foals and land aimed at reducing aerosol exposure to virulent R. equi is likely to yield significant reductions in the prevalence and severity of R. equi pneumonia. ..
  23. Karabasil N, Čobanović N, Vučićević I, Stajković S, Becskei Z, Forgách P, et al. Association of the severity of lung lesions with carcass and meat quality in slaughter pigs. Acta Vet Hung. 2017;65:354-365 pubmed publisher
    ..67% and 33.33% of the cases, respectively. Bronchopneumonia was found in 33.33% of the cases. By immunohistochemical examination, 26...
  24. Bexfield N, Foale R, Davison L, Watson P, Skelly B, Herrtage M. Management of 13 cases of canine respiratory disease using inhaled corticosteroids. J Small Anim Pract. 2006;47:377-82 pubmed
    ..Inhaled corticosteroids were used for the management of chronic bronchitis and eosinophilic bronchopneumopathy in 13 dogs, and these may have the advantage of reducing side effects associated with oral corticosteroids. ..
  25. Klochkov O, Guchev I, Ivanitsa G. [The use of azithromycin in prophylaxis of respiratory infections occurred in the organized collectives, clinical sequelae]. Voen Med Zh. 2004;325:43-7, 80 pubmed
    ..The empirical therapy using benzylpenicillin was considered as effective in 90.5% [95% CI=84.3-94.9%] and in 89.4% [95% CI=76.9-96.5%] cases in the control group and group of prophylaxis respectively (P=0.84). ..
  26. Nys M, Deby Dupont G, Habraken Y, Legrand Poels S, Kohnen S, Ledoux D, et al. Bronchoalveolar lavage fluids of ventilated patients with acute lung injury activate NF-kappaB in alveolar epithelial cell line: role of reactive oxygen/nitrogen species and cytokines. Nitric Oxide. 2003;9:33-43 pubmed
    ..In BALs obtained in 67 patients (16 bronchopneumonia, 14 infected ARDS, 20 ARDS, and 17 ALI patients without bronchopneumonia and no ARDS), we measured endotoxin, ..
  27. Testuz A, Le Gal G, Righini M, Bounameaux H, Perrier A. Influence of specific alternative diagnoses on the probability of pulmonary embolism. Thromb Haemost. 2006;95:958-62 pubmed
    ..2. Bronchopneumonia (OR 0.4, 95% CI 0.2 to 0.7) and cancer (OR 0.6, 95% CI 0.3 to 1...
  28. Ehlers J, Schimmel D, Sachse K, Boehnke H, Schöss P. [Toxin-producing pasteurellas in a cattle herd]. Dtsch Tierarztl Wochenschr. 1993;100:488-91 pubmed
    ..producing dermonecrotic Pasteurella toxin, were isolated from the noses of calves in a herd with enzootic bronchopneumonia. In some blood sera, antitoxin was detected...
  29. Hoffman W, Lee J, Kovacs K, Chen H, Yaghmai F. Johanson-Blizzard syndrome: autopsy findings with special emphasis on hypopituitarism and review of the literature. Pediatr Dev Pathol. 2007;10:55-60 pubmed
    ..The patient died of acute bronchopneumonia at the age of 4 years...
  30. Francoz D, Lapointe J, Wellemans V, Desrochers A, Caswell J, Stott J, et al. Immunoglobulin G2 deficiency with transient hypogammaglobulinemia and chronic respiratory disease in a 6-month-old Holstein heifer. J Vet Diagn Invest. 2004;16:432-5 pubmed
    ..Blood lymphocyte proliferation and neutrophil function tests were normal. Results of immunologic assays indicated IgG2 deficiency with transient hypogammaglobulinemia. ..
  31. Cabrera Cordero J, Adefna Pérez R, Leal Mursulí A, Castellanos González J, Izquierdo Lara F, Cabrera Alfonso S. [Pneumothorax in human immunodeficiency virus infected patients]. Cir Esp. 2008;84:221-5 pubmed
    ..The present study attempts to identify and characterise the behaviour of a group of variables in HIV patients with this complication...
  32. Brunnström H, Englund E. Cause of death in patients with dementia disorders. Eur J Neurol. 2009;16:488-92 pubmed publisher
    ..The two most common causes of death were bronchopneumonia (38.4%) and ischaemic heart disease (23.1%), whilst neoplastic diseases were uncommon (3.8%)...
  33. Girardi C, Tonnellier M, Goldstein I, Sartorius A, Wallet F, Rouby J. Lung deposition of continuous and intermittent intravenous ceftazidime in experimental Pseudomonas aeruginosa bronchopneumonia. Intensive Care Med. 2006;32:2042-8 pubmed
    ..administered either continuously or intermittently was compared in ventilated piglets with experimental bronchopneumonia. Prospective experimental study Eighteen anesthetized and ventilated piglets Bronchopneumonia was produced by ..
  34. Mosbah A, Abdellatif N, Sorour E, Awadallah M. Serum SP-D levels as a biomarker of lung injury in children suffering of bronchopneumonia. J Egypt Soc Parasitol. 2012;42:25-32 pubmed
    The efficacy of SP-D concentration as a useful biomarker of the severity of lung injury in children with bronchopneumonia with or without chronic airway disease was studied...
  35. Giguere S, Prescott J. Clinical manifestations, diagnosis, treatment, and prevention of Rhodococcus equi infections in foals. Vet Microbiol. 1997;56:313-34 pubmed
    ..equi infections have essentially remained unchanged. This article reviews the various clinical manifestations and summarizes recent advances in diagnosis, treatment and prevention of R. equi infections in foals. ..
  36. Rudkjøbing V, Thomsen T, Alhede M, Kragh K, Nielsen P, Johansen U, et al. True microbiota involved in chronic lung infection of cystic fibrosis patients found by culturing and 16S rRNA gene analysis. J Clin Microbiol. 2011;49:4352-5 pubmed publisher
    ..A correspondence between culturing and the molecular methods was observed. In conclusion, standard culturing seems reliable for the identification of the dominating pathogens. ..
  37. Schuller S, Valentin S, Remy B, Jespers P, Foulon S, Van Israël N, et al. Analytical, physiologic, and clinical validation of a radioimmunoassay for measurement of procollagen type III amino terminal propeptide in serum and bronchoalveolar lavage fluid obtained from dogs. Am J Vet Res. 2006;67:749-55 pubmed
    ..Data suggest that the use of PIIINP as a marker of pathologic fibrosis might be limited in growing dogs. ..
  38. Soeiro A, Hovnanian A, Parra E, Canzian M, Capelozzi V. Post-mortem histological pulmonary analysis in patients with HIV/AIDS. Clinics (Sao Paulo). 2008;63:497-502 pubmed
    ..A total of 197 men and 53 women were studied. The mean age was 36 years. Bacterial bronchopneumonia was present in 36% (91 cases) and Pneumocystis jiroveci pneumonia in 27% (68) of patients...
  39. Kelly L, Rieder M, van den Anker J, Malkin B, Ross C, Neely M, et al. More codeine fatalities after tonsillectomy in North American children. Pediatrics. 2012;129:e1343-7 pubmed publisher
    ..These cases demonstrate that analgesia with codeine or other opioids that use the CYP2D6 pathway after adenotonsillectomy may not be safe in young children with obstructive sleep apnea syndrome. ..
  40. Muller R, Quabeck K, Beelen D, Lohr E, Schaefer U. [Roentgen diagnosis of pulmonary complications following allogeneic bone marrow transplantation--application of and experience with digital luminescence radiography]. Pneumologie. 1991;45:977-86 pubmed
    ..The x-ray morphology, clinical and sometimes autopsy findings were correlated with the occurrence of pulmonary complications subsequent to bone marrow transplant. ..
  41. Ubrig B, Roth S, Hertle L. 54 year-old female with recurrent bronchopneumonia and tumor of the left kidney. ScientificWorldJournal. 2004;4 Suppl 1:353-6 pubmed
  42. Fitzpatrick C, Biggs K, Atkins B, Quance Fitch F, Dixon P, Savage S, et al. Prolonged low-volume resuscitation with HBOC-201 in a large-animal survival model of controlled hemorrhage. J Trauma. 2005;59:273-81; discussion 281-3 pubmed
    ..These data suggest that hemoglobin-based oxygen carriers are superior to the current standard of care for resuscitation in far-forward military operations. ..
  43. Hogardt M, Ulrich J, Riehn Kopp H, Tummler B. EuroCareCF quality assessment of diagnostic microbiology of cystic fibrosis isolates. J Clin Microbiol. 2009;47:3435-8 pubmed publisher
    ..The shortcomings in the diagnostics of rare and emerging pathogens point to the need for continuing education in CF microbiology and suggest the establishment of CF microbiology reference laboratories. ..
  44. Axisa B, Fishwick G, Bolia A, Thompson M, London N, Bell P, et al. Complications following peripheral angioplasty. Ann R Coll Surg Engl. 2002;84:39-42 pubmed
    ..Major medical morbidity (bronchopneumonia, stroke, renal failure, myocardial infarction) complicated 33/1377 procedures (2.4%)...
  45. Friedlander A, Fessler M. A 70-year-old man with migratory pulmonary infiltrates. Chest. 2006;130:1269-74 pubmed
  46. Nakajima D, Cypel M, Bonato R, Machuca T, Iskender I, Hashimoto K, et al. Ex Vivo Perfusion Treatment of Infection in Human Donor Lungs. Am J Transplant. 2016;16:1229-37 pubmed publisher
    ..In conclusion, EVLP treatment of infected donor lungs with broad-spectrum antibiotics significantly reduced BAL bacterial counts and endotoxin levels and improved donor lung function. ..
  47. Ashraf M. Myeloid leukaemoid reaction in a surgical case. Bristol Med Chir J. 1969;84:72-6 pubmed
  48. Rizza V, Coletti G, Grimaldi A, Clemente K, Di Cocco P, D ANGELO M, et al. A rare case of herpes simplex type 1 bronchopneumonia associated with cardiomegaly in renal transplantation. Transplant Proc. 2011;43:1210-2 pubmed publisher
    ..Only an early, accurate diagnosis with efficient treatment permitted resolution of the problem. Our report stresses the difficulty of HSV2B clinical diagnosis and treatment. ..
  49. Reynolds J, Banerjee A. Imaging pneumonia in immunocompetent and immunocompromised individuals. Curr Opin Pulm Med. 2012;18:194-201 pubmed publisher
    ..Three basic patterns of radiographic abnormality are recognized: lobar (nonsegmental) pneumonia; bronchopneumonia (lobular pneumonia); and interstitial pneumonia...
  50. Ghosh G. Clinical evaluation of acute respiratory distress and chest wheezing in infants: a few practical difficulties. Indian Pediatr. 2002;39:1172; author reply 1173-4 pubmed
  51. Wang Z, Li X, Li D, Li Y. Clinical features of 167 children with the novel influenza A (H1N1) virus infection in Xi'an, China. Turk J Pediatr. 2012;54:99-104 pubmed
    ..All of the patients fully recuperated from the 2009 epidemic influenza A (H1N1) infection with one exception. ..
  52. Ondruschka B, Habeck J, Hädrich C, Dreßler J, Bayer R. Rare cause of natural death in forensic setting: hemophagocytic syndrome. Int J Legal Med. 2016;130:777-81 pubmed publisher
    ..Microscopic and microbiological examination revealed a pneumococcal bronchopneumonia and hemophagocytic lesions in the bone marrow...
  53. Spraker T, Hibler C, Schoonveld G, Adney W. Pathologic changes and microorganisms found in bighorn sheep during a stress-related die-off. J Wildl Dis. 1984;20:319-27 pubmed
    ..The cause of death was a subacute to chronic bronchopneumonia and the primary etiologic agents isolated from the respiratory system were a Pasteurella sp., P...