Summary: Experience-based techniques for problem-solving, learning, and discovery that find a solution which is not guaranteed to be optimal, but sufficient for a given set of goals.

Top Publications

  1. Brusco M, Stolze H, Hoffman M, Steinley D. A simulated annealing heuristic for maximum correlation core/periphery partitioning of binary networks. PLoS ONE. 2017;12:e0170448 pubmed publisher
    ..Core/periphery analyses of problem solving, trust, and information sharing networks for the frontline employees and managers of a consumer packaged goods manufacturer are provided to illustrate the use of the model. ..
  2. Krumholz E, Libourel I. Thermodynamic Constraints Improve Metabolic Networks. Biophys J. 2017;113:679-689 pubmed publisher
    ..We conclude that metabolic network analysis confirmed the validity of the thermodynamic constraints, and that thermodynamic poise information is actionable during network reconciliation. ..
  3. Swan A, Stekel D, Hodgman C, Allaway D, Alqahtani M, Mobasheri A, et al. A machine learning heuristic to identify biologically relevant and minimal biomarker panels from omics data. BMC Genomics. 2015;16 Suppl 1:S2 pubmed publisher
    ..Feature reduction methods are advantageous for the analysis of omics data in the field of rheumatology, as the applications of such techniques are likely to result in improvements in diagnosis, treatment and drug discovery. ..
  4. Moreno Armendáriz M, Hagan M, Alba E, Rubio J, Cruz Villar C, Leguizamón G. Advances in Neural Networks and Hybrid-Metaheuristics: Theory, Algorithms, and Novel Engineering Applications. Comput Intell Neurosci. 2016;2016:3263612 pubmed
  5. Yoon H, Hwang S, Choi J, Lee Y, Jeong D, Park K. REM sleep estimation based on autonomic dynamics using R-R intervals. Physiol Meas. 2017;38:631-651 pubmed publisher
    ..Further, long-term sleep monitoring could provide useful information to clinicians and patients for the diagnosis and treatments of sleep-related disorders and individual health care. ..
  6. Miller K, Kim T. Examining student heuristic usage in a hydrogen bonding assessment. Biochem Mol Biol Educ. 2017;45:411-416 pubmed publisher
    ..The use of heuristics is further supported by the students' corresponding responses to the open-ended assessment item...
  7. Madni S, Abd Latiff M, Abdullahi M, Abdulhamid S, Usman M. Performance comparison of heuristic algorithms for task scheduling in IaaS cloud computing environment. PLoS ONE. 2017;12:e0176321 pubmed publisher
  8. Koppe G, Mallien A, Berger S, Bartsch D, Gass P, Vollmayr B, et al. CACNA1C gene regulates behavioral strategies in operant rule learning. PLoS Biol. 2017;15:e2000936 pubmed publisher
    ..The results may also have clinical implications for treating psychiatric disorders. ..
  9. Joshi R, Mortel H, Feijs L, Andriessen P, Pul C. The heuristics of nurse responsiveness to critical patient monitor and ventilator alarms in a private room neonatal intensive care unit. PLoS ONE. 2017;12:e0184567 pubmed publisher
    ..The aim of this study was to determine the factors that modulate nurse responsiveness to critical patient monitor and ventilator alarms in the context of a private room neonatal intensive care setting...

More Information


  1. Palluzzi F, Ferrari R, Graziano F, Novelli V, Rossi G, Galimberti D, et al. A novel network analysis approach reveals DNA damage, oxidative stress and calcium/cAMP homeostasis-associated biomarkers in frontotemporal dementia. PLoS ONE. 2017;12:e0185797 pubmed publisher
    ..We emphasized the key molecular actors in these processes, proposing them as novel FTD biomarkers that could be crucial for further epidemiological and molecular studies. ..
  2. Zhao W, Chen J, Perkins R, Liu Z, Ge W, Ding Y, et al. A heuristic approach to determine an appropriate number of topics in topic modeling. BMC Bioinformatics. 2015;16 Suppl 13:S8 pubmed publisher
    ..We understand that additional investigation is needed to substantiate the method's theoretical basis, and to establish its generalizability in terms of dataset characteristics. ..
  3. Fu S, Tarone A, Sze S. Heuristic pairwise alignment of de Bruijn graphs to facilitate simultaneous transcript discovery in related organisms from RNA-Seq data. BMC Genomics. 2015;16 Suppl 11:S5 pubmed publisher
  4. Tsai T, Chang H, Chen Y, Chang Y. Determinants of user acceptance of a specific social platform for older adults: An empirical examination of user interface characteristics and behavioral intention. PLoS ONE. 2017;12:e0180102 pubmed publisher
    ..Fourteen user interface evaluation heuristics proposed by Zhang et al...