Genomes and Genes
Summary: The sensation of sound.
Publications310 found, 100 shown here
- Cetaceans on a molecular fast track to ultrasonic hearingYang Liu
School of Life Sciences, East China Normal University, Shanghai, China
Curr Biol 20:1834-9. 2010..Echolocation in toothed whales demands exceptional high-frequency hearing , and both echolocation and ultrasonic hearing have also evolved independently in bats [4, 5]...
- A comprehensive analysis of hearing preservation after radiosurgery for vestibular schwannomaIsaac Yang
Department of Neurological Surgery, University of California at San Francisco, California 94117, USA
J Neurosurg 112:851-9. 2010..b>Hearing preservation rates in GKS series suggest very favorable outcomes without the possible acute morbidity associated ..
- Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearingA Rusch
Physiologisches Institut, Gmelinstrasse 5, and Sektion Sensorische Biophysik, Hals Nasen Ohren Klinik, Röntgenweg 11, Universität T ubingen, D 72076 Tubingen, Germany
Proc Natl Acad Sci U S A 95:15758-62. 1998To elucidate the role of thyroid hormone receptors (TRs) alpha1 and beta in the development of hearing, cochlear functions have been investigated in mice lacking TRalpha1 or TRbeta...
- High-frequency tinnitus without hearing loss does not mean absence of deafferentationNathan Weisz
Department of Psychology, University of Konstanz, Germany
Hear Res 222:108-14. 2006..The absence of audiometrically detectable hearing loss however poses a challenge to this rather generalizing assumption...
- The hearing gene Prestin unites echolocating bats and whalesYing Li
Department of Ecology and Evolutionary Biology, University of Michigan, Ann Arbor, MI 48109, USA
Curr Biol 20:R55-6. 2010..substantially in many aspects , we here report the surprising finding that the bottlenose dolphin, a toothed whale, is clustered with microbats in the gene tree constructed using protein sequences encoded by the hearing gene Prestin.
- The functional significance of mu rhythms: translating "seeing" and "hearing" into "doing"Jaime A Pineda
Department of Cognitive Science and Neuroscience, University of California, San Diego, La Jolla, CA 92037 0515, USA
Brain Res Brain Res Rev 50:57-68. 2005..processing function that links perception and action-specifically, the transformation of "seeing" and "hearing" into "doing...
- Parallel signatures of sequence evolution among hearing genes in echolocating mammals: an emerging model of genetic convergenceK T J Davies
School of Biological and Chemical Sciences, Queen Mary University of London, London, UK
Heredity (Edinb) 108:480-9. 2012..in the Prestin gene among some bats and cetaceans suggest that parallel adaptations for high-frequency hearing have taken place during the evolution of echolocation...
- The hearing gene Prestin reunites echolocating batsGang Li
School of Life Science, East China Normal University, Shanghai 200062, China
Proc Natl Acad Sci U S A 105:13959-64. 2008..Echolocating bats use ultrasound for orientation and hunting and possess the highest frequency hearing of all mammals...
- The sensory and motor roles of auditory hair cellsRobert Fettiplace
Department of Physiology, University of Wisconsin Medical School, 185 Medical Sciences Building, 1300 University Avenue, Madison, Wisconsin 53706, USA
Nat Rev Neurosci 7:19-29. 2006..Both motor mechanisms are probably needed to provide the high sensitivity and frequency discrimination of the mammalian cochlea...
- Key functions for gap junctions in skin and hearingClaire A Scott
Centre for Cutaneous Research, The Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
Biochem J 438:245-54. 2011..3 and Cx31 which lead to skin disease and deafness. Functional studies with Cx proteins have given insights into disease-associated mechanisms and non-gap junctional roles for Cx proteins...
- Review series: The cell biology of hearingMartin Schwander
Department of Cell Biology, Dorris Neuroscience Center, The Scripps Research Institute, La Jolla, CA 92037, USA
J Cell Biol 190:9-20. 2010..The study of genes that are linked to deafness has provided insights into the cell biological mechanisms that control hair cell development and their function as mechanosensors...
- The neural basis of Drosophila gravity-sensing and hearingAzusa Kamikouchi
Sensory Systems Laboratory, Institute of Zoology, University of Cologne, 50923 Cologne, Germany
Nature 458:165-71. 2009..Here we focus on two of the remaining and less understood prime sensory modalities: graviception and hearing. We show that the fly has implemented both sensory modalities into a single system, Johnston's organ, which ..
- Effects of hearing aid amplification and stimulus intensity on cortical auditory evoked potentialsCurtis J Billings
Department of Speech and Hearing Sciences, University of Washington, Seattle, WA 98105, USA
Audiol Neurootol 12:234-46. 2007b>Hearing aid amplification can be used as a model for studying the effects of auditory stimulation on the central auditory system (CAS)...
- Hearing lips and seeing voices: how cortical areas supporting speech production mediate audiovisual speech perceptionJeremy I Skipper
Department of Neurology, The University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA
Cereb Cortex 17:2387-99. 2007....
- The remarkable cochlear amplifierJ Ashmore
Department of Neuroscience, Physiology and Pharmacology and UCL Ear Institute, Gower Street, London WC1E 6BT, UK
Hear Res 266:1-17. 2010..These experiments are presently lacking but if successfully performed would have an enormous impact on our understanding of the cochlear amplifier...
- Hearing visual motion in depthNorimichi Kitagawa
Department of Psychology, Tokyo Metropolitan University, 1 1, Minami Osawa, Hachioji shi, Tokyo 192 0397, Japan
Nature 416:172-4. 2002..The results provide psychophysical evidence that, for processing of motion in depth, the auditory system responds to both auditory changing intensity and visual motion in depth...
- Structural determinants of cadherin-23 function in hearing and deafnessMarcos Sotomayor
Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
Neuron 66:85-100. 2010..The structures define an uncharacterized cadherin family and, with simulations, suggest mechanisms underlying inherited deafness and how cadherin-23 may bind with itself and with protocadherin-15 to form the tip link...
- Relationship between swim bladder morphology and hearing abilities--a case study on Asian and African cichlidsTanja Schulz-Mirbach
Department of Behavioral Biology, University of Vienna, Vienna, Austria
PLoS ONE 7:e42292. 2012..A few comparative studies have shown that these morphological specializations may enhance hearing abilities...
- Baby hands that move to the rhythm of language: hearing babies acquiring sign languages babble silently on the handsLaura Ann Petitto
Department of Psychological and Brain Sciences and Department of Education, Raven House, Dartmouth College, Hanover, NH 03755, USA
Cognition 93:43-73. 2004..Two groups of hearing babies were studied over time (ages 6, 10, and 12 months), equal in all developmental respects except for the ..
- Reading, hearing, and the planum temporaleBradley R Buchsbaum
Department of Health and Human Services, Unit on Integrative Neuroimaging, Clinical Brain Disorders Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD 20892 1365, USA
Neuroimage 24:444-54. 2005..Moreover, increasing the smoothing window to 10 mm obliterates activation in the PT, suggesting that failure to find PT activation in past studies may relate to this factor...
- Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisitionByung Yoon Choi
Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, NIH, Rockville, Maryland, USA
J Clin Invest 121:4516-25. 2011Mutations in human SLC26A4 are a common cause of hearing loss associated with enlarged vestibular aqueducts (EVA)...
- Otoacoustic emissions in a hearing conservation program: general applicability in longitudinal monitoring and the relation to changes in pure-tone thresholdsHiske W Helleman
Clinical and Experimental Audiology, ENT Department, Academic Medical Centre, Amsterdam, The Netherlands
Int J Audiol 49:410-9. 2010The hearing status of workers (N = 233) in a printing office was assessed twice within seventeen months by pure-tone audiometry and otoacoustic emissions (OAEs)...
- Audition in sciaenid fishes with different swim bladder-inner ear configurationsJohn U Ramcharitar
Department of Biology and Neuroscience and Cognitive Science Program, University of Maryland, College Park, Maryland 20742, USA
J Acoust Soc Am 119:439-43. 2006We investigated how morphological differences in the auditory periphery of teleost fishes may relate to hearing capabilities...
- Lefties get it "right" when hearing tool soundsJames W Lewis
Department of Physiology and Phamacology, West Virginia University, WV 26506 9229, USA
J Cogn Neurosci 18:1314-30. 2006..In right-handers, we previously reported that hearing hand-manipulated tool sounds preferentially activates a left hemisphere network of motor-related brain regions ..
- Electrical stimulation of the midbrain for hearing restoration: insight into the functional organization of the human central auditory systemHubert H Lim
Otorhinolaryngology Department, Hannover Medical University, 30625 Hannover, Germany
J Neurosci 27:13541-51. 2007The cochlear implant can restore speech perception in patients with sensorineural hearing loss. However, it is ineffective for those without an implantable cochlea or a functional auditory nerve...
- Normal hearing is not enough to guarantee robust encoding of suprathreshold features important in everyday communicationDorea Ruggles
Department of Biomedical Engineering, Boston University Hearing Research Center, Boston, MA 02215, USA
Proc Natl Acad Sci U S A 108:15516-21. 2011Normal hearing" is typically defined by threshold audibility, even though everyday communication relies on extracting key features of easily audible sound, not on sound detection...
- The role of temporal fine structure processing in pitch perception, masking, and speech perception for normal-hearing and hearing-impaired peopleBrian C J Moore
Department of Experimental Psychology, University of Cambridge, Downing Street, Cambridge, CB2 3EB, UK
J Assoc Res Otolaryngol 9:399-406. 2008..Evidence is reviewed suggesting that cochlear hearing loss reduces the ability to use TFS cues...
- The case for early identification of hearing loss in children. Auditory system development, experimental auditory deprivation, and development of speech perception and hearingY S Sininger
Children s Auditory Research and Evaluation Center, University of California Davis Medical Center, USA
Pediatr Clin North Am 46:1-14. 1999..Although it is not visible to observers, infants with hearing are learning to process speech and understand language and are quite linguistically sophisticated by 1 year of ..
- Prestin's role in cochlear frequency tuning and transmission of mechanical responses to neural excitationMarcia M Mellado Lagarde
School of Life Sciences, University of Sussex, Falmer, Brighton BN1 9QG, United Kingdom
Curr Biol 18:200-2. 2008..Prestin is crucial for defining sharp and sensitive cochlear frequency tuning by reducing the sensitivity of the low-frequency tail of the tuning curve, although this necessitates a cochlear amplifier to determine the narrowly tuned tip...
- Hearing syllables by seeing visual stimuliLutz Jancke
University of Zurich, Institute of Psychology, Division of Neuropsychology, Treichlerstr 10, Switzerland
Eur J Neurosci 19:2603-8. 2004..To overcome the detrimental effects of scanner noise, one group of subjects was trained to vividly imagine hearing a syllable while a flashlight was presented. A control group did not receive this training...
- Hearing speech sounds: top-down influences on the interface between audition and speech perceptionMatthew H Davis
MRC Cognition and Brain Sciences Unit, Cambridge, UK
Hear Res 229:132-47. 2007..We propose that top-down interactive mechanisms within auditory networks play an important role in explaining the perception of spoken language...
- Two interdependent TRPV channel subunits, inactive and Nanchung, mediate hearing in DrosophilaZhefeng Gong
Biology Department, University of Virginia, Charlottesville, Virginia 22904, USA
J Neurosci 24:9059-66. 2004b>Hearing in Drosophila depends on the transduction of antennal vibration into receptor potentials by ciliated sensory neurons in Johnston's organ, the antennal chordotonal organ...
- Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cellsTina Pangrsic
InnerEarLab, Department of Otolaryngology and Center for Molecular Physiology of the Brain, University Medical Center Gottingen, Gottingen, Germany
Nat Neurosci 13:869-76. 2010..that an aspartate to glycine substitution in the C(2)F domain of the synaptic vesicle protein otoferlin impaired hearing by reducing vesicle replenishment in the pachanga mouse model of human deafness DFNB9...
- Phase-sensitive optical coherence tomography imaging of the tissue motion within the organ of Corti at a subnanometer scale: a preliminary studyRuikang K Wang
Oregon Health and Science University, Department of Biomedical Engineering, CH13B, 3303 Southwest Bond Avenue, Portland, Oregon 97239, USA
J Biomed Opt 15:056005. 2010b>Hearing loss can mean severe impairment to the quality of life. However, the biomechanical mechanisms of how the hearing organ, i.e...
- Rethinking sound detection by fishesArthur N Popper
Department of Biology and Center for Comparative and Evolutionary Biology of Hearing, University of Maryland, College Park, MD 20742, USA
Hear Res 273:25-36. 2011In this paper we reconsider the designation of fishes as being either "hearing specialists" or "hearing generalists," and recommend dropping the terms...
- Musical experience and the aging auditory system: implications for cognitive abilities and hearing speech in noiseAlexandra Parbery-Clark
Auditory Neuroscience Laboratory, Northwestern University, Evanston, Illinois, United States of America
PLoS ONE 6:e18082. 2011..Although aging is generally accompanied by hearing loss, this perceptual decline cannot fully account for the difficulties experienced by older adults for hearing ..
- Harmonin mutations cause mechanotransduction defects in cochlear hair cellsNicolas Grillet
Department of Cell Biology, Institute for Childhood and Neglected Disease, The Scripps Research Institute, La Jolla, CA 92037, USA
Neuron 62:375-87. 2009..interactions with CDH23 and F-actin control harmonin localization in stereocilia and are necessary for normal hearing. In mice expressing a mutant harmonin protein that prevents UTLD formation, the sensitivity of hair bundles to ..
- Tricellulin is a tight-junction protein necessary for hearingSaima Riazuddin
Section on Human Genetics, Laboratory of Molecular Genetics, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, MD 20850, USA
Am J Hum Genet 79:1040-51. 2006..spaces of the organ of Corti; the separation from one another by epithelial barriers is required for normal hearing. TRIC encodes tricellulin, a recently discovered tight-junction (TJ) protein that contributes to the structure ..
- Tinnitus in hamsters following exposure to intense soundHenry E Heffner
Department of Psychology, University of Toledo, Toledo, OH 43606, USA
Hear Res 170:83-95. 2002..5 and 1 h did not. The degree of hearing loss produced by the tone exposure was assessed using behavioral and auditory brainstem response (ABR) procedures...
- Effects of hearing aid fitting on the perceptual characteristics of tinnitusG Moffat
Laboratoire de Neurobiologie Integrative et Adaptative, UMR CNRS 6149, 3 Place Victor Hugo, Marseille, F 13331 Cedex 03, France
Hear Res 254:82-91. 2009Restoration of auditory input through the use of hearing aids has been proposed as a potentially important means of altering tinnitus among those tinnitus sufferers who experience significant sensorineural hearing loss...
- Targeted three-dimensional immunohistochemistry reveals localization of presynaptic proteins Bassoon and Piccolo in the rat calyx of Held before and after the onset of hearingAnna Dondzillo
Department of Anatomy and Cell Biology, University of Heidelberg, 69120 Heidelberg, Germany
J Comp Neurol 518:1008-29. 2010..3D localization of Bassoon and Piccolo in the rat calyx of Held between postnatal days 9 and 21, the period of hearing onset characterized by pronounced structural and functional changes...
- Development of form and function in the mammalian cochleaMichael C Kelly
Department of Cell Biology, Emory University, 615 Michael Street, Atlanta, GA 30322, USA
Curr Opin Neurobiol 19:395-401. 2009....
- The corpus callosum in dichotic listening studies of hemispheric asymmetry: a review of clinical and experimental evidenceRene Westerhausen
Department of Biological and Medical Psychology, Cognitive Neuroscience Group, University of Bergen, Jonas Lies vei 91, N 5009 Bergen, Norway
Neurosci Biobehav Rev 32:1044-54. 2008..The review has also revealed how inter-individual variability in callosal fiber structure affects both bottom-up and top-down performance on the dichotic listening task...
- A TRPV family ion channel required for hearing in DrosophilaJanghwan Kim
Department of Genetics, Hanwha Chemical Co R and D Center, Sinsung dong, Yusung Gu, Daejeon 305 345, Korea
Nature 424:81-4. 2003..Antennal sound-evoked potentials are completely absent in mutants lacking Nan, showing that it is an essential component of the chordotonal mechanotransducer...
- Seasonal plasticity of peripheral auditory frequency sensitivityJoseph A Sisneros
Department of Neurobiology and Behavior, Cornell University, Ithaca, New York 14853, USA
J Neurosci 23:1049-58. 2003....
- Prestin is required for electromotility of the outer hair cell and for the cochlear amplifierM Charles Liberman
Department of Otology and Laryngology, Harvard Medical School and Eaton Peabody Laboratory, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
Nature 419:300-4. 2002b>Hearing sensitivity in mammals is enhanced by more than 40 dB (that is, 100-fold) by mechanical amplification thought to be generated by one class of cochlear sensory cells, the outer hair cells...
- Frequency organization of the 40-Hz auditory steady-state response in normal hearing and in tinnitusChristian Wienbruch
Department of Psychology, University of Konstanz, Box D25, 78457 Konstanz, Germany
Neuroimage 33:180-94. 2006..representations in the region of primary auditory cortex (PAC) between subjects with chronic tinnitus and hearing impairment and normal hearing controls...
- Is there a role of visual cortex in spatial hearing?Ulrike Zimmer
Section Neuropsychology, Department of Cognitive Neurology, Hertie Institute for Clinical Brain Research, University of Tubingen, Tubingen, Germany
Eur J Neurosci 20:3148-56. 2004..This result suggests a relation of neural processing in the visual cortex and the transformation of auditory spatial coordinates responsible for maintaining the perceptual alignment of audition and vision with changes in gaze direction...
- Expression of a potassium current in inner hair cells during development of hearing in miceC J Kros
Department of Physiology, School of Medical Sciences, University of Bristol, UK
Nature 394:281-4. 1998..This change in potassium channel expression turns the inner hair cell from a regenerative, spiking pacemaker into a high-frequency signal transducer...
- Comparison of auditory electrophysiological responses in normal-hearing patients with and without tinnitusS Singh
Department of Otolaryngology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
J Laryngol Otol 125:668-72. 2011Tinnitus is a disturbing symptom and is often the main reason for otology referral. It is usually associated with hearing loss of varying aetiology, and is thought to begin in the cochlea, with later abnormal central activity...
- Reversible long-term changes in auditory processing in mature auditory cortex in the absence of hearing loss induced by passive, moderate-level sound exposureMartin Pienkowski
Departments of Physiology and Pharmacology, University of Calgary, 2500 University Drive NW, Calgary, Alberta, Canada
Ear Hear 33:305-14. 2012..damage to the hair cells of the cochlea and the auditory nerve fibers, even if the resulting partial loss of hearing sensitivity, usually accompanied by tinnitus, disappears within hours or days of the exposure...
- Mice lacking the B1 subunit of H+ -ATPase have normal hearingHongwei Dou
Center for Hearing and Deafness Research, Department of Pediatric Otolaryngology, Cincinnati Children s Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229 3039, USA
Hear Res 180:76-84. 2003..clinical data from individuals affected by autosomal recessive distal renal tubular acidosis with sensorineural hearing loss...
- Analysis of cochlear protein profiles of Wistar, Sprague-Dawley, and Fischer 344 rats with normal hearing functionSamson Jamesdaniel
Center for Hearing and Deafness, University at Buffalo, The State University of New York, Buffalo, NY 14214, USA
J Proteome Res 8:3520-8. 2009..Normal hearing function of the animals was ascertained using distortion product otoacoustic emissions (DPOAE)...
- Output sound pressure levels of personal music systems and their effect on hearingAjith Kumar
Dr MV Shetty College of Speech and Hearing, Vidyanagar, Mangalore 575 013, India
Noise Health 11:132-40. 2009..Further, the effect of these PMS on hearing was evaluated by comparing the distortion product otoacoustic emissions and high frequency pure tone thresholds (..
- Tuning of the outer hair cell motor by membrane cholesterolLavanya Rajagopalan
Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Huffington Center on Aging and Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA
J Biol Chem 282:36659-70. 2007..We observed that alterations of cochlear cholesterol modulate hearing in mice...
- Ion flow in cochlear hair cells and the regulation of hearing sensitivityRobert Patuzzi
The Auditory Laboratory M311, School of Biomedical, Biomolecular and Chemical Sciences, The University of Western Australia, 35 Stirling Highway, Crawley 6009, Australia
Hear Res 280:3-20. 2011..how ion transport proteins in the hair cells of the mammalian cochlea work to produce a sensitive but stable hearing organ...
- A network for sensory-motor integration: what happens in the auditory cortex during piano playing without acoustic feedback?Simon Baumann
Department of Neuropsychology, University of Zurich, Treichlerstrasse 10, CH 8032 Zurich, Switzerland
Ann N Y Acad Sci 1060:186-8. 2005..We provide evidence for the existence of a neuronal network of secondary and higher-order areas belonging to the auditory and motor modality that is important in the integration of auditory and motor domains...
- A systematic review of studies measuring and reporting hearing aid usage in older adults since 1999: a descriptive summary of measurement toolsElvira Pérez
National Biomedical Research Unit in Hearing, National Institute for Health Research NIHR, Nottingham, United Kingdom
PLoS ONE 7:e31831. 2012..conducted to identify and quality assess how studies published since 1999 have measured and reported the usage of hearing aids in older adults...
- Hearing and morphological specializations of the mojarra (Eucinostomus argenteus)Eric Parmentier
Laboratoire de Morphologie Fonctionnelle et Evolutive, Institut de Chimie, Bât B6, Universite de Liege, B 4000 Liege, Belgium
J Exp Biol 214:2697-701. 2011..b>Hearing tests show the mojarra has better hearing sensitivity than other species of fish without a connection...
- The otolithic organ as a receptor of vestibular hearing revealed by vestibular-evoked myogenic potentials in patients with inner ear anomaliesKianoush Sheykholeslami
Department of Otolaryngology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku 113 0033, Japan
Hear Res 165:62-7. 2002..The contribution of this response to the perception of loud sounds is discussed. It is concluded that vestibular response to sound might be used to assist in the rehabilitation of deafness...
- Tectorial membrane travelling waves underlie abnormal hearing in Tectb mutant miceRoozbeh Ghaffari
Speech and Hearing Bioscience and Technology Program, Harvard MIT Division of Health Sciences and Technology, Cambridge, Massachusetts 02139, USA
Nat Commun 1:96. 2010Remarkable sensitivity and exquisite frequency selectivity are hallmarks of mammalian hearing, but their underlying mechanisms remain unclear...
- Drosophila auditory organ genes and genetic hearing defectsPingkalai R Senthilan
Department of Cellular Neurobiology, University of Gottingen, Julia Lermontowa Weg 3, 37077 Gottingen, Germany
Cell 150:1042-54. 2012..Only four of these genes had previously been associated with fly hearing, yet one in five of the genes that we identified has a human cognate that is implicated in hearing disorders...
- Hearing colors, tasting shapesVilayanur S Ramachandran
Sci Am 288:52-9. 2003
- Two-year decline in vision but not hearing is associated with memory decline in very old adults in a population-based sampleK J Anstey
Prince of Wales Medical Research Institute, University of New South Wales, Sydney, Australia
Gerontology 47:289-93. 2001..However, the nature of the association is still unclear, particularly with respect to whether sensory and cognitive function are causally related...
- A false killer whale adjusts its hearing when it echolocatesPaul E Nachtigall
Marine Mammal Research Program, Hawaii Institute of Marine Biology, University of Hawaii, PO Box 1106, Kailua, HI 96734, USA
J Exp Biol 211:1714-8. 2008The use of auditory evoked potential (AEP) measurements has added considerably to knowledge of the hearing mechanisms of marine mammals...
- A genetic approach to understanding auditory functionK P Steel
Medical Research Council Institute of Hearing Research, University of Nottingham, Nottingham, UK
Nat Genet 27:143-9. 2001..auditory transduction, as it makes no assumptions about the nature or expression level of molecules essential for hearing. We review here some of the major advances in our understanding of auditory function resulting from the recent ..
- Role of corticofugal feedback in hearingNobuo Suga
Department of Biology, Washington University, One Brookings Drive, St Louis, MO 63130, USA
J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:169-83. 2008..The corticofugal system has multiple functions. One of the most important functions is the improvement and adjustment (reorganization) of subcortical auditory signal processing for cortical signal processing...
- Development of ultrasound detection in American shad (Alosa sapidissima)D M Higgs
Department of Biology, University of Windsor, Windsor, Ontario, N9B 3P4 Canada
J Exp Biol 207:155-63. 2004..Thus, it appears that ultrasound-detecting clupeiformes have undergone structural modification of the utricle that allows detection of ultrasonic stimulation...
- Gamma knife radiosurgery for vestibular schwannoma: early hearing outcomes and evaluation of the cochlear doseJohn M Lasak
Department of Surgery, The University of Kansas School of Medicine, Wichita, Kansas, USA
Otol Neurotol 29:1179-86. 2008To evaluate the hearing outcomes for a group of unilateral vestibular schwannoma patients treated with gamma knife radiosurgery and to determine if the cochlear radiation dose affects hearing outcome measures.
- Emergence of hearing in the chicken embryoTimothy A Jones
Department of Communication Sciences and Disorders, School of Allied Health Sciences, East Carolina University, Greenville, NC 27858, USA
J Neurophysiol 96:128-41. 2006It is commonly held that hearing generally begins on incubation day 12 (E12) in the chicken embryo (Gallus domesticus). However, little is known about the response properties of cochlear ganglion neurons for ages younger than E18...
- Discrimination and identification of azimuth using spectral shapeDANIEL E SHUB
Speech and Hearing Bioscience and Technology Program, Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA
J Acoust Soc Am 124:3132-41. 2008..Measurements are reported for normal-hearing subjects, who listened with only one ear, and effectively monaural subjects, who had substantial unilateral ..
- Essential role of retinoblastoma protein in mammalian hair cell development and hearingCyrille Sage
Neurology Service, Center for Nervous System Repair, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Proc Natl Acad Sci U S A 103:7345-50. 2006..However, adult pRb(-/-) mice exhibit profound hearing loss due to progressive degeneration of the organ of Corti...
- Prestin, the motor protein of outer hair cellsJing Zheng
Department of Communication Sciences and Disorders, Auditory Physiology Laboratory, The Hugh Knowles Center, Northwestern University, Evanston, Ill 60208, USA
Audiol Neurootol 7:9-12. 2002..Prestin shares overall structure similarity with this anion transporter family. Recently, intracellular anions (chloride or bicarbonate) were found to be essential for OHC electromotility and prestin's function...
- Hearing illusory sounds in noise: the timing of sensory-perceptual transformations in auditory cortexLars Riecke
Department of Cognitive Neuroscience, Faculty of Psychology and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands
Neuron 64:550-61. 2009..Such fluctuations could facilitate stable hearing of fragmented sounds in natural environments.
- Evolution and function of auditory systems in insectsA Stumpner
Institut für Zoologie und Anthropologie, Universitat Gottingen, Germany
Naturwissenschaften 88:159-70. 2001..The behavioural context in which hearing has evolved has strongly determined the design and properties of the auditory system...
- Ontogenetic development of auditory sensitivity and sound production in the squeaker catfish Synodontis schoutedeniWalter Lechner
University of Vienna, Department of Behavioural Biology, Althanstrasse 14, 1090 Vienna, Austria
BMC Biol 8:10. 2010Surveys of ontogenetic development of hearing and sound production in fish are scarce, and the ontogenetic development of acoustic communication has been investigated in only two fish species so far...
- Sound-induced differential motion within the hearing organAnders Fridberger
Center for Hearing and Communication Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
Nat Neurosci 6:446-8. 2003
- Sound localization under perturbed binaural hearingMarc M Van Wanrooij
Department of Biophysics, Radboud University Nijmegen, Geert Grooteplein 21, 6525 EZ Nijmegen, The Netherlands
J Neurophysiol 97:715-26. 2007This paper reports on the acute effects of a monaural plug on directional hearing in the horizontal (azimuth) and vertical (elevation) planes of human listeners...
- Temporal integration vs. parallel processing: coping with the variability of neuronal messages in directional hearing of insectsB Ronacher
Department of Biology, Humboldt University, D 10099 Berlin, Germany
Eur J Neurosci 12:2147-56. 2000..Using the directional hearing of the grasshopper Chorthippus biguttulus (Ch...
- Otoacoustic emissions in universal hearing screening: which day after birth should we examine the newborns?Stavros Korres
ENT Department of Athens National University, Ippokration Hospital, Athens, Greece
ORL J Otorhinolaryngol Relat Spec 65:199-201. 2003Transiently evoked otoacoustic emissions (TEOAEs) have been widely used in universal newborn hearing screening programs...
- Soundscapes and the sense of hearing of fishesRichard Fay
Parmly Hearing Institute, Loyola University Chicago, Chicago, IL 60626, USA
Integr Zool 4:26-32. 2009..A call is made to better understand underwater soundscapes, and the associated behaviors they determine in fishes...
- A comparative study of hearing ability in fishes: the auditory brainstem response approachT N Kenyon
T H Morgan School of Biological Sciences, University of Kentucky, Lexington 40506 0225, USA
J Comp Physiol A 182:307-18. 1998..ABR) techniques, an electrophysiological far-field recording method widely used in clinical evaluation of human hearing, were adapted for fishes to overcome the major limitations of traditional behavioral and electrophysiological ..
- Subjective and objective results after bilateral cochlear implantation in adultsRoman D Laske
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Zurich, Switzerland
Otol Neurotol 30:313-8. 2009..To assess and compare subjective and objective results after bilateral cochlear implantation with a special emphasis on time interval between the first and second implant...
- Neural signature of the conscious processing of auditory regularitiesTristan A Bekinschtein
Cognitive Neuro Imaging Unit, Institut Fédératif de Recherche 49, Institut National de la Sante et de la Recherche Medicale, 91191 Gif sur Yvette, France
Proc Natl Acad Sci U S A 106:1672-7. 2009..This simple electrophysiological marker could thus serve as a useful clinical tool...
- Developmental regulation of spontaneous activity in the Mammalian cochleaNicolas X Tritsch
The Solomon H Snyder Department of Neuroscience and Department of Otolaryngology, Head and Neck Surgery, Johns Hopkins University, Baltimore, Maryland 21205, USA
J Neurosci 30:1539-50. 2010Neurons in the developing auditory system fire bursts of action potentials before the onset of hearing. This spontaneous activity promotes the survival and maturation of auditory neurons and the refinement of synaptic connections in ..
- Development of form and function in peripheral auditory structures of the zebrafish (Danio rerio)Dennis M Higgs
Department of Biology, University of Maryland, College Park, Maryland 20742, USA
J Acoust Soc Am 113:1145-54. 2003..of frequency range coincided with the development of Weberian ossicles in zebrafish, suggesting that changes in hearing ability in this species are driven more by development of auxiliary specializations than by the ear itself...
- Hearing ability in three clownfish speciesEric Parmentier
Laboratoire de Morphologie Fonctionnelle et Evolutive, Institut de Chimie, Bat B6c, Universite de Liege, B 4000 Liege, Belgium
J Exp Biol 212:2023-6. 2009..Data on the hearing ability of these fish are, however, needed to show that they have the sensory ability to detect the frequencies ..
- Hearing sounds, understanding actions: action representation in mirror neuronsEvelyne Kohler
Istituto di Fisiologia Umana, Universita di Parma, Italy, Dipartimento di Psicologia, Universita di Parma, Italy
Science 297:846-8. 2002....
- The origin of spontaneous activity in the developing auditory systemNicolas X Tritsch
The Solomon H Snyder Department of Neuroscience, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA
Nature 450:50-5. 2007..Spontaneous ATP-dependent signalling rapidly subsides after the onset of hearing, thereby preventing this experience-independent activity from interfering with accurate encoding of sound...
- Rapid confocal imaging for measuring sound-induced motion of the hearing organ in the apical regionStefan Jacob
Karolinska Institutet, Center for Hearing and Communication Research, Departments of Otolaryngology and Clinical Neuroscience, M1 Karolinska Universitetssjukhuset, SE 171 76 Stockholm, Sweden
J Biomed Opt 12:021005. 2007..The hearing organ is imaged with a standard laser scanning confocal microscope during sound stimulation...
- Hyperbaric oxygen and steroid therapy for idiopathic sudden sensorineural hearing lossTakeyuki Fujimura
Department of Otorhinolaryngology, School of Medicine, University of Occupational and Environmental Health, 1 1 Iseigaoka, Yahatanishi ku, Kitakyushu, 807 8555, Japan
Eur Arch Otorhinolaryngol 264:861-6. 2007..of hyperbaric oxygen (HBO) therapy combined with steroid administration for idiopathic sudden sensorineural hearing loss (ISSNHL) in comparison with that of steroid administration alone...
- The effect of isoflurane, halothane and pentobarbital on noise-induced hearing loss in miceJong Woo Chung
Department of Otolaryngology, Asan Medical Center, College of Medicine, University of Ulsan, Songpa Gu, Seoul, Korea
Anesth Analg 104:1404-8, table of contents. 2007Ear surgery using mastoid drills can lead to noise-induced hearing loss (NIHL). We investigated whether inhaled anesthetics or pentobarbital could have protective effects on NIHL in mice.
- Audiometric patterns and prognosis in sudden sensorineural hearing loss in southern TaiwanNing Chia Chang
Department of Otolaryngology, Kaohsiung Medical University, Chung Ho Memorial Hospital, Taiwan
Otolaryngol Head Neck Surg 133:916-22. 2005To investigate factors affecting the prognosis of sudden sensorineural hearing loss (SSNHL).
- Choosing between measures: comparison of EQ-5D, HUI2 and HUI3 in persons with hearing complaintsJanneke P C Grutters
Department of Clinical Epidemiology and Medical Technology Assessment, University Hospital Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
Qual Life Res 16:1439-49. 2007To generate insight into the differences between utility measures EuroQol 5D (EQ-5D), Health Utilities Index Mark II (HUI2) and Mark III (HUI3) and their impact on the incremental cost-effectiveness ratio (ICER) for hearing aid fitting
- Neural correlates of human action observation in hearing and deaf subjectsDavid Corina
Department of Psychology, University of Washington, Seattle, USA Center for Mind and Brain, University of California, Davis, USA
Brain Res 1152:111-29. 2007..However, the results indicate that this neural consistency across motion classes is true primarily for hearing subjects. Data from deaf signers shows a non-uniform response to different classes of human actions...
- Orphan glutamate receptor delta1 subunit required for high-frequency hearingJiangang Gao
Department of Developmental Neurobiology, St Jude Children s Research Hospital, Memphis, TN 38105, USA
Mol Cell Biol 27:4500-12. 2007..Our findings show that the orphan GluRdelta1 plays an essential role in high-frequency hearing and ionic homeostasis in the basal cochlea, and the locus encoding GluRdelta1 represents a candidate gene for ..
- Evaluation of the relation between audiometric and psychometric measures of hearing after tympanoplastyAstrid G W Korsten-Meijer
Department of Otorhinolaryngology, University Hospital Groningen, Groningen, The Netherlands
Eur Arch Otorhinolaryngol 263:256-62. 2006..b>Hearing (dis)ability was measured by means of pure-tone audiometry and a validated self-assessment questionnaire: the (..
- A prospective study on radiation-induced changes in hearing functionFranziska Herrmann
Department of Oto Rhino Laryngology, University of Technology Dresden, Dresden, Germany
Int J Radiat Oncol Biol Phys 65:1338-44. 2006To quantitate changes in hearing function after radiotherapy for head-and-neck tumors.
- Social cognition as a mediator of cognition and outcome among deaf and hearing people with schizophreniaHeather K Horton
School of Social Welfare, University at Albany, Richardson Hall 280, 135 Western, Avenue, Albany, NY 12203, United States
Schizophr Res 105:125-37. 2008..The current project tests the mediating potency of these two domains of social cognition among deaf and hearing people with schizophrenia...
- Measuring hearing organ vibration patterns with confocal microscopy and optical flowAnders Fridberger
Center for Hearing and Communication Research and Department of Otolaryngology, Karolinska Institutet, Stockholm, Sweden
Biophys J 86:535-43. 2004..These methods were used for investigating the motion pattern of the vibrating hearing organ...
- Vibratory interneurons in the non-hearing cave cricket indicate evolutionary origin of sound processing elements in EnsiferaNatasa Stritih
National Institute of Biology, Department of Entomology, Vecna pot 111, SI 1000 Ljubljana, Slovenia
Zoology (Jena) 112:48-68. 2009Tympanal hearing organs in the front tibiae of ensiferan insects supposedly evolved from vibration-sensitive tibial organs (TO), like those in the cave cricket Troglophilus neglectus (Rhaphidophoridae)...
- Can L-carnitine prevent drug-induced hearing loss?Gilda Kalinec; Fiscal Year: 2004b>Hearing loss is a prevalent and chronic health condition that affects between 22 and 28 million Americans...
- Characterization of Hearing Status in the Jackson Heart Study CohortJohn Schweinfurth; Fiscal Year: 2007The contribution of cardiovascular disease (CVD) to the development of sensorineural hearing loss (SNHL) is not well understood. The cochlea is known to be very sensitive to ischemia...
- Evaluation of Hearing Loss in Farmworkers, Texas- Mexico Border AreaMartha S Vela Acosta; Fiscal Year: 2007Occupational hearing loss is the most common occupational disease in the United States. It affects all workers regardless of age, gender, or industrial sector...
- Cloning & Functional Studies of Deafness MutationsKenneth R Johnson; Fiscal Year: 2010The mouse is an excellent model for studying human hearing disorders because of the similarities in inner ear anatomy, function, and pathology...
- Effects of Sensorineural Hearing Loss on Robust Speech CodingMichael G Heinz; Fiscal Year: 2010A great challenge in diagnosing and treating hearing impairment comes from the fact that people with similar degrees of hearing loss may have different speech recognition abilities...
- WIDEBAND CLINICAL DIAGNOSIS AND MONITORING OF MIDDLE-EAR AND COCHLEAR FUNCTIONDOUGLAS KEEFE; Fiscal Year: 2009..Monitoring of Middle-Ear and Cochlear Function A wideband (WB) acoustic test battery has the potential to improve hearing screening and diagnosis of middle-ear and cochlear dysfunction across the age range...
- WIDEBAND CLINICAL DIAGNOSIS AND MONITORING OF MIDDLE-EAR AND COCHLEAR FUNCTIONDOUGLAS H contact KEEFE; Fiscal Year: 2010..Monitoring of Middle-Ear and Cochlear Function A wideband (WB) acoustic test battery has the potential to improve hearing screening and diagnosis of middle-ear and cochlear dysfunction across the age range...
- Hearing Therapies for the FutureGabrielle Saunders; Fiscal Year: 2007..The conference objective is to expand understanding and facilitate effective treatment of noise induced hearing loss (NIHL)...
- Method of Wind Noise Suppression in Hearing AidsGARY ELKO; Fiscal Year: 2007..and refine a promising novel digital technique we have developed at MH Acoustics for reducing wind noise in hearing aids...
- Eradication of Occupational Noise-Induced Hearing LossKevin Michael; Fiscal Year: 2007Noise-induced hearing loss remains one of the most common industrial diseases in U.S...
- HEARING HAZARD ASSOCIATED WITH INDUSTRIAL NOISE EXPOSUREROGER HAMERNIK; Fiscal Year: 2009..Application of the EEH in many industrial environments severely underestimates hearing loss...
- HEARING HAZARD ASSOCIATED WITH INDUSTRIAL NOISE EXPOSURERoger P Hamernik; Fiscal Year: 2010..Application of the EEH in many industrial environments severely underestimates hearing loss...
- Understanding thyroid hormone regulation of neurogenesis in the cochleaMIRNA MUSTAPHA CHAIB; Fiscal Year: 2010b>Hearing impairment is prevalent and has significant implications for quality of life. There are currently no available clinical cures for hereditary inner ear disease or reliable means of preventing age related hearing loss...
- HEARING DAMAGE AMONG NEWLY-HIRED CONSTRUCTION WORKERSNoah Seixas; Fiscal Year: 2003Noise-induced hearing loss (NIHL) is among the most common occupational afflictions, especially to construction workers...
- Defining Antigenic Targets of Autoimmune Sensorineural Hearing LossThomas E Carey; Fiscal Year: 2010Autoimmune hearing loss (AHL) is a poorly understood disorder that can lead to profound and permanent hearing loss. Inner ear damage in AHL can be antibody mediated or cell mediated...
- High frequency auditory sensitivity in birdsBernard Lohr; Fiscal Year: 2004..goal of this research is to advance the understanding of the limitations, diversity, and comparative aspects of hearing in birds...
- Development of the Mouse Cochlea DatabasePeter Santi; Fiscal Year: 2007Among the 5 senses, hearing is fundamental for acquiring language, communication, and navigating through our environment...
- Development of the Mouse Cochlea DatabasePETER ALAN SANTI; Fiscal Year: 2010Among the five senses, hearing is fundamental for acquiring language, communication, and navigating through our environment...
- CTL2 ELISA: A Diagnostic Test for Autoimmune Hearing LossVijay Kumar; Fiscal Year: 2007DESCRIPTION (Provided by applicant): Autoimmune hearing loss (AHL) is a subset of sensorineural hearing loss (SNHL) in which there is a sudden onset, or rapidly progressing and/or fluctuating hearing loss that often progresses to ..
- EFFECTS OF ASYMMETRIC HEARING IN ACOUSTIC LISTENERS AND COCHLEAR IMPLANT USERSJill Firszt; Fiscal Year: 2009..Many patients function with noticeable asymmetry in hearing. We propose to study the effects of asymmetric hearing in three patient populations...
- EFFECTS OF ASYMMETRIC HEARING IN ACOUSTIC LISTENERS AND COCHLEAR IMPLANT USERSJill B Firszt; Fiscal Year: 2010..Many patients function with noticeable asymmetry in hearing. We propose to study the effects of asymmetric hearing in three patient populations...
- EFFECTS OF ASYMMETRIC HEARING IN ACOUSTIC LISTENERS AND COCHLEAR IMPLANT USERSJill Firszt; Fiscal Year: 2009..Many patients function with noticeable asymmetry in hearing. We propose to study the effects of asymmetric hearing in three patient populations...
- PHYLOGENY AND ONTOGENY OF AN AUDITORY SYSTEMDAVID YAGER; Fiscal Year: 2004..changes occur in the sensory periphery and the CNS during the evolutionary transition between earless and eared (hearing) animals...
- Spontaneous Sign Systems in Five CulturesSusan Goldin Meadow; Fiscal Year: 2009..The participants are deaf children whose hearing parents have not yet exposed them to sign language, and whose hearing losses are so profound as to preclude ..
- Spontaneous Sign Systems in Five CulturesSusan Goldin Meadow; Fiscal Year: 2007..The participants are deaf children whose hearing parents have not yet exposed them to sign language, and whose hearing losses are so profound as to preclude ..
- Spontaneous Sign Systems in Five CulturesSUSAN J GOLDIN MEADOW; Fiscal Year: 2010..The participants are deaf children whose hearing parents have not yet exposed them to sign language, and whose hearing losses are so profound as to preclude ..
- Rescue of cortical inhibitory synapses following developmental hearing lossVibhakar C Kotak; Fiscal Year: 2011..this idea, cortical inhibitory synapse strength is reduced dramatically following even moderate developmental hearing loss. However, whether inhibitory synapse maturation displays a critical period is poorly understood...