short term memory

Summary

Summary: Temporary storage of information for a few seconds to hours, as opposed to long-term memory which refers to material stored for days, years, or a lifetime.

Top Publications

  1. ncbi The capacity of visual working memory for features and conjunctions
    S J Luck
    Department of Psychology, University of Iowa, Iowa City 52242 1407, USA
    Nature 390:279-81. 1997
  2. ncbi Storage and executive processes in the frontal lobes
    E E Smith
    Department of Psychology, Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109 1109, USA
    Science 283:1657-61. 1999
  3. ncbi The role of working memory in visual selective attention
    J W de Fockert
    Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Science 291:1803-6. 2001
  4. ncbi Working memory: looking back and looking forward
    Alan Baddeley
    Department of Psychology, University of York, York YO10 5DD, UK
    Nat Rev Neurosci 4:829-39. 2003
  5. ncbi The demonstration of short-term consolidation
    P Jolicoeur
    Department of Psychology, University of Waterloo, Ontario, Canada
    Cogn Psychol 36:138-202. 1998
  6. ncbi Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia
    Dwight Dickinson
    VISN 5 Mental Illness Research, Education and Clinical Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Arch Gen Psychiatry 64:532-42. 2007
  7. pmc Stimulus-specific delay activity in human primary visual cortex
    John T Serences
    Department of Psychology, University of California, San Diego, La Jolla, CA 92093 0109, USA
    Psychol Sci 20:207-14. 2009
  8. ncbi The magical number 4 in short-term memory: a reconsideration of mental storage capacity
    N Cowan
    Department of Psychological Sciences, University of Missouri, Columbia, MO 65211, USA
    Behav Brain Sci 24:87-114; discussion 114-85. 2001
  9. ncbi Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down
    Joseph H Callicott
    Clinical Brain Disorders Branch, NIMH NIH, Bldg 10, Rm 4D 20, MSC 1389, Bethesda, MD 20892 1389, USA
    Am J Psychiatry 160:2209-15. 2003
  10. ncbi Frontal lobes and human memory: insights from functional neuroimaging
    P C Fletcher
    Research Department of Psychiatry, Cambridge University, Addenbrooke s Hospital, Cambridge, UK
    Brain 124:849-81. 2001

Detail Information

Publications356 found, 100 shown here

  1. ncbi The capacity of visual working memory for features and conjunctions
    S J Luck
    Department of Psychology, University of Iowa, Iowa City 52242 1407, USA
    Nature 390:279-81. 1997
    ....
  2. ncbi Storage and executive processes in the frontal lobes
    E E Smith
    Department of Psychology, Mental Health Research Institute, University of Michigan, Ann Arbor, MI 48109 1109, USA
    Science 283:1657-61. 1999
    ..Two of the fundamental executive processes are selective attention and task management. Both processes activate the anterior cingulate and dorsolateral prefrontal cortex...
  3. ncbi The role of working memory in visual selective attention
    J W de Fockert
    Department of Psychology, University College London, Gower Street, London WC1E 6BT, UK
    Science 291:1803-6. 2001
    ..These findings confirm a major role for working memory in the control of visual selective attention...
  4. ncbi Working memory: looking back and looking forward
    Alan Baddeley
    Department of Psychology, University of York, York YO10 5DD, UK
    Nat Rev Neurosci 4:829-39. 2003
  5. ncbi The demonstration of short-term consolidation
    P Jolicoeur
    Department of Psychology, University of Waterloo, Ontario, Canada
    Cogn Psychol 36:138-202. 1998
    ..The results suggested that STC has limited capacity and that it requires central processing mechanisms. Additional evidence suggested that no memory for T1 was formed in STM when STC was not engaged...
  6. ncbi Overlooking the obvious: a meta-analytic comparison of digit symbol coding tasks and other cognitive measures in schizophrenia
    Dwight Dickinson
    VISN 5 Mental Illness Research, Education and Clinical Center, Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Arch Gen Psychiatry 64:532-42. 2007
    ..In focusing on potentially localizable cognitive impairments, the schizophrenia meta-analytic literature has overlooked the largest single impairment: on digit symbol coding tasks...
  7. pmc Stimulus-specific delay activity in human primary visual cortex
    John T Serences
    Department of Psychology, University of California, San Diego, La Jolla, CA 92093 0109, USA
    Psychol Sci 20:207-14. 2009
    ....
  8. ncbi The magical number 4 in short-term memory: a reconsideration of mental storage capacity
    N Cowan
    Department of Psychological Sciences, University of Missouri, Columbia, MO 65211, USA
    Behav Brain Sci 24:87-114; discussion 114-85. 2001
    ..Reasons why pure capacity estimates fall within a narrow range are discussed and a capacity limit for the focus of attention is proposed...
  9. ncbi Complexity of prefrontal cortical dysfunction in schizophrenia: more than up or down
    Joseph H Callicott
    Clinical Brain Disorders Branch, NIMH NIH, Bldg 10, Rm 4D 20, MSC 1389, Bethesda, MD 20892 1389, USA
    Am J Psychiatry 160:2209-15. 2003
    ..The authors' goal was to explore this phenomenon...
  10. ncbi Frontal lobes and human memory: insights from functional neuroimaging
    P C Fletcher
    Research Department of Psychiatry, Cambridge University, Addenbrooke s Hospital, Cambridge, UK
    Brain 124:849-81. 2001
    ..We expect that the neuroimaging techniques will provide an important part of this enterprise...
  11. ncbi Functional neuroimaging correlates of mental fatigue induced by cognition among chronic fatigue syndrome patients and controls
    Dane B Cook
    Department of Veterans Affairs William S Middleton Memorial Veterans Hospital, Madison, WI 53706, USA
    Neuroimage 36:108-22. 2007
    ..Our results suggest an association between subjective feelings of mental fatigue and brain responses during fatiguing cognition...
  12. ncbi Prefrontal cortex dysfunction during working memory performance in schizophrenia: reconciling discrepant findings
    Dara S Manoach
    Department of Psychiatry, Massachusetts General Hospital East and Harvard Medical School, 36 First Avenue, Room 420, 02129, Charlestown, MA, USA
    Schizophr Res 60:285-98. 2003
    ..In combination with other techniques, neuroimaging can identify the neural circuitry responsible for WM deficits and elucidate the contribution of each anatomical component...
  13. ncbi Functional imaging of working memory after 24 hr of total sleep deprivation
    Michael W L Chee
    Cognitive Neuroscience Laboratory, SingHealth Research Laboratories, Singapore 169611, Singapore
    J Neurosci 24:4560-7. 2004
    ..Our findings provide neural correlates to explain why task performance in relatively more complex tasks is better preserved relative to simpler ones after SD...
  14. ncbi The working memory networks of the human brain
    David E J Linden
    Wolfson Centre of Clinical and Cognitive Neuroscience, School of Psychology, University of Wales Bangor, North Wales Clinical School, Bangor, Wales
    Neuroscientist 13:257-67. 2007
    ..Finally, the author highlights open questions for cognitive neuroscience research of working memory, such as that of the mechanisms for integrating different types of content (binding) or those providing the link to long-term memory...
  15. ncbi Impaired set-shifting and dissociable effects on tests of spatial working memory following the dopamine D2 receptor antagonist sulpiride in human volunteers
    Mitul A Mehta
    Department of Psychiatry, Level E4, Addenbrooke s Hospital, University of Cambridge, Cambridge, CB2 2QQ, UK
    Psychopharmacology (Berl) 176:331-42. 2004
    ..These include working memory and set-shifting deficits. Theories of DA function have predicted that distraction or impaired switching may be important determinants of such deficits...
  16. ncbi Visual working memory represents a fixed number of items regardless of complexity
    Edward Awh
    University of Oregon, Eugene, OR 97403 1227, USA
    Psychol Sci 18:622-8. 2007
    ..Finally, a correlational analysis suggested a two-factor model of working memory ability, in which the number and resolution of representations in working memory correspond to distinct dimensions of memory ability...
  17. ncbi Gamma amplitudes are coupled to theta phase in human EEG during visual perception
    Tamer Demiralp
    Istanbul University, Istanbul Faculty of Medicine, Department of Physiology, Turkey
    Int J Psychophysiol 64:24-30. 2007
    ..Instead of theta phase modulating gamma amplitude, it is also conceivable that focal gamma activity needs to be downsampled to theta activity, before it can interact with more distant brain regions...
  18. pmc Working memory as an emergent property of the mind and brain
    B R Postle
    Department of Psychology, University of Wisconsin Madison, 1202 West Johnson Street, Madison, WI 53726, USA
    Neuroscience 139:23-38. 2006
    ..Evidence from behavioral, neuropsychological, electrophysiological, and neuroimaging studies, from monkeys and humans, is considered, as is the question of how to interpret delay-period activity in the prefrontal cortex...
  19. ncbi A mechanistic account of striatal dopamine function in human cognition: psychopharmacological studies with cabergoline and haloperidol
    Michael J Frank
    Department of Psychology and Program in NeuroscienceUniversity of Arizona, Tucson, AZ 85721, USA
    Behav Neurosci 120:497-517. 2006
    ..Drug effects interacted with baseline working memory span in all tasks. Taken together, the results support a unified account of the role of dopamine in modulating cognitive processes that depend on the basal ganglia...
  20. pmc Critical role of the hippocampus in memory for sequences of events
    Norbert J Fortin
    Laboratory of Cognitive Neurobiology, Department of Psychology, Boston University, Boston, Massachusetts 02215, USA
    Nat Neurosci 5:458-62. 2002
    ..These findings support the hypothesis that hippocampal networks mediate associations between sequential events that constitute elements of an episodic memory...
  21. ncbi Activity of neurons in cortical area MT during a memory for motion task
    James W Bisley
    Department of Neurobiology and Anatomy and Center for Visual Science, University of Rochester, Rochester, New York 14642, USA
    J Neurophysiol 91:286-300. 2004
    ..These results support the hypothesis that MT neurons actively participate in the successful execution of all aspects of the task requiring processing and remembering visual motion...
  22. ncbi Orienting attention to locations in internal representations
    Ivan C Griffin
    Department of Experimental Psychology, University of Oxford, UK
    J Cogn Neurosci 15:1176-94. 2003
    ..Retro-cues also showed additional neural processes to be involved in orienting to an internal representation, including early effects over frontal electrodes...
  23. ncbi Flexible, capacity-limited activity of posterior parietal cortex in perceptual as well as visual short-term memory tasks
    Daniel J Mitchell
    MRC Cognition and Brain Sciences Unit, Cambridge, UK
    Cereb Cortex 18:1788-98. 2008
    ..The differential influence of item load across perceptual tasks is consistent with task requirements affecting the form of these representations...
  24. ncbi Functional MRI studies of spatial and nonspatial working memory
    M D'ESPOSITO
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA, USA
    Brain Res Cogn Brain Res 7:1-13. 1998
    ..4 (1994) 207-211], a reconsideration of the previous imaging literature data suggested that a dorsal/ventral subdivision of prefrontal cortex may depend upon the type of processing performed upon the information held in working memory...
  25. pmc Are there multiple visual short-term memory stores?
    Ilja G Sligte
    Cognitive Neuroscience Group, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 3:e1699. 2008
    ..The current experiments address this issue and explore the capacity, stability, and duration of fragile VSTM representations...
  26. ncbi Encoding strategies dissociate prefrontal activity from working memory demand
    Daniel Bor
    Medical Research Council Cognition and Brain Sciences Unit, 15 Chaucer Road, Cambridge CB2 2EF, United Kingdom
    Neuron 37:361-7. 2003
    ..The results show that, even when memory demand decreases, organization of working memory contents into higher level chunks is associated with increased prefrontal activity...
  27. ncbi Visual search remains efficient when visual working memory is full
    G F Woodman
    Department of Psychology, University of Iowa, Iowa City 52242 1407, USA
    Psychol Sci 12:219-24. 2001
    ..These results suggest that visual search requires minimal visual working memory resources, a conclusion that is inconsistent with theories that propose a close link between attention and working memory...
  28. ncbi The capacity of visual short-term memory is set both by visual information load and by number of objects
    G A Alvarez
    Department of Psychology, Harvard University, Cambridge, MA 02138, USA
    Psychol Sci 15:106-11. 2004
    ..Thus, both the visual information load and number of objects impose capacity limits on visual short-term memory...
  29. ncbi Neural fate of ignored stimuli: dissociable effects of perceptual and working memory load
    Do Joon Yi
    Department of Psychology, Yale University, PO Box 208205, 2 Hillhouse Avenue, New Haven, Connecticut 06520, USA
    Nat Neurosci 7:992-6. 2004
    ..These dissociable effects of perceptual and working memory load clarify how task-irrelevant, unattended stimuli are processed in category-selective areas in human ventral visual cortex...
  30. pmc Medial temporal lobe activity predicts successful relational memory binding
    Deborah E Hannula
    Center for Neuroscience, University of California, Davis, California 95618, USA
    J Neurosci 28:116-24. 2008
    ..These results indicate that the hippocampus and related MTL structures contribute to successful encoding and retrieval of relational information in visual short-term memory...
  31. ncbi Attentional modulation of object representations in working memory
    Jöran Lepsien
    Brain and Cognition Laboratory, Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
    Cereb Cortex 17:2072-83. 2007
    ..The results show that directed attention can modulate maintenance of specific representations in WM, and help define the interplay between the domains of attention and WM...
  32. ncbi Dissociable neural mechanisms supporting visual short-term memory for objects
    Yaoda Xu
    Department of Psychology, Yale University, New Haven, Connecticut 06520 8205, USA
    Nature 440:91-5. 2006
    ..VSTM capacity is therefore determined both by a fixed number of objects and by object complexity...
  33. ncbi Neural correlates of spatial working memory in humans: a functional magnetic resonance imaging study comparing visual and tactile processes
    E Ricciardi
    Laboratory of Clinical Biochemistry and Molecular Biology, University of Pisa, Via Roma 55, I 56126 Pisa, Italy
    Neuroscience 139:339-49. 2006
    ....
  34. ncbi The right hippocampus participates in short-term memory maintenance of object-location associations
    Carinne Piekema
    Department of Psychonomics, Helmholtz Instituut, Utrecht University, Heidelberglaan 2, 3584 CS Utrecht, The Netherlands
    Neuroimage 33:374-82. 2006
    ..The present results suggest a hippocampal involvement in active maintenance when feature combinations that include spatial information have to be maintained online...
  35. ncbi Organization of visual short-term memory
    Y Jiang
    Department of Psychology, Yale University, New Haven, CT 06520 8205, USA
    J Exp Psychol Learn Mem Cogn 26:683-702. 2000
    ..In summary, the authors proposed that VSTM stores the relational information of individual visual items on the basis of global spatial configuration...
  36. pmc Understanding the function of visual short-term memory: transsaccadic memory, object correspondence, and gaze correction
    Andrew Hollingworth
    Department of Psychology, University of Iowa, Iowa City, IA 52242 1407, USA
    J Exp Psychol Gen 137:163-81. 2008
    ..These findings demonstrate that VSTM plays a direct role in a fundamentally important aspect of visually guided behavior, and they suggest the existence of previously unknown links between VSTM representations and the occulomotor system...
  37. ncbi Maintenance of multiple working memory items by temporal segmentation
    O Jensen
    Radboud University Nijmegen, F C Donders Centre for Cognitive Neuroimaging, Kapitelweg 29, 6525 EN Nijmegen, The Netherlands
    Neuroscience 139:237-49. 2006
    ..The theta/gamma mechanism has also received support from a large set of electrophysiological findings, however, more experimental work is required to further substantiate or falsify the model...
  38. ncbi Striatal contributions to working memory: a functional magnetic resonance imaging study in humans
    Simon J G Lewis
    Cambridge Centre for Brain Repair, Forvie Site, Addenbrooke s Hospital, Cambridge, CB2 2PY, UK
    Eur J Neurosci 19:755-60. 2004
    ..These results suggest an essential and specific role for the caudate nucleus in executive function, which may underlie the cognitive disturbances observed in frontostriatal neurodegenerative disorders such as Parkinson's disease...
  39. ncbi Working memory maintenance contributes to long-term memory formation: neural and behavioral evidence
    Charan Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, CA 95616, USA
    J Cogn Neurosci 17:994-1010. 2005
    ....
  40. ncbi Restricted and regulated overexpression reveals calcineurin as a key component in the transition from short-term to long-term memory
    I M Mansuy
    Center for Neurobiology and Behavior, College of Physicians and Surgeons of Columbia University, New York State Psychiatric Institute, New York 10032, USA
    Cell 92:39-49. 1998
    ..Our behavioral results suggest that calcineurin has a role in the transition from short- to long-term memory, which correlates with a novel intermediate phase of LTP...
  41. ncbi Directional signals in the prefrontal cortex and in area MT during a working memory for visual motion task
    Daniel Zaksas
    Department of Neurobiology and Anatomy, Department of Brain and Cognitive Science, and Center for Visual Science, University of Rochester, Rochester, New York 14642, USA
    J Neurosci 26:11726-42. 2006
    ..PFC neurons reflect task-related information about visual motion and represent decisions that may be based, in part, on the comparison in MT between the remembered sample and test...
  42. ncbi Effects of cytotoxic hippocampal lesions in mice on a cognitive test battery
    Robert M J Deacon
    Department of Experimental Psychology, University of Oxford, South Parks Road, UK
    Behav Brain Res 133:57-68. 2002
    ..These results are largely consistent with findings in hippocampal lesioned rats on the same or similar tasks, and reflect a major impairment of spatial cognition, with relative sparing of non-spatial task performance...
  43. ncbi Neuroimaging studies of working memory: a meta-analysis
    Tor D Wager
    University of Michigan, Ann Arbor, Michigan, USA
    Cogn Affect Behav Neurosci 3:255-74. 2003
    ..Finally, we consider a potential fourth executive function: selective attention to features of a stimulus to be stored in WM, which leads to increased probability of activating the medial prefrontal cortex (BA 32) in storage tasks...
  44. ncbi When loading working memory reduces distraction: behavioral and electrophysiological evidence from an auditory-visual distraction paradigm
    Iria SanMiguel
    University of Barcelona, Catalonia, Spain
    J Cogn Neurosci 20:1131-45. 2008
    ..Moreover, as these results contradict predictions of the load theory of selective attention and cognitive control, it is suggested that the WM load effects on distraction depend on the nature of the distractor-target relationships...
  45. ncbi The multi-component model of working memory: explorations in experimental cognitive psychology
    G Repovs
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Neuroscience 139:5-21. 2006
    ..With many questions still open and new issues emerging, we believe that the multicomponent model will continue to stimulate research while providing a comprehensive functional description of working memory...
  46. ncbi Working memory for visual objects: complementary roles of inferior temporal, medial temporal, and prefrontal cortex
    C Ranganath
    Center for Neuroscience and Department of Psychology, University of California at Davis, 1544 Newton Court, Davis, CA 95616, USA
    Neuroscience 139:277-89. 2006
    ....
  47. ncbi Spatial processing in the monkey frontal eye field. II. Memory responses
    M M Umeno
    Laboratory of Sensorimotor Research, National Eye Institute, Bethesda, Maryland 20892, USA
    J Neurophysiol 86:2344-52. 2001
    ..We suggest that the frontal eye field maintains a spatially accurate representation of the visual world that is not dependent on constant or continuous visual stimulation, and can last for several minutes...
  48. ncbi Under the curve: critical issues for elucidating D1 receptor function in working memory
    G V Williams
    Department of Psychiatry, Yale University School of Medicine, 300 George Street, Suite 901, New Haven, CT 06511, USA
    Neuroscience 139:263-76. 2006
    ..If we look under the bell-shaped curve of prefrontal dopamine function, it is the relationship between neuromodulation and cognitive function that promises to bridge our knowledge between molecule and mind...
  49. ncbi Content- and task-specific dissociations of frontal activity during maintenance and manipulation in visual working memory
    Harald M Mohr
    Department of Psychiatry, Johann Wolfgang Goethe Universitat, D 60590 Frankfurt am Main, Germany
    J Neurosci 26:4465-71. 2006
    ..We suggest that the enhanced demand on cognitive resources in manipulation compared with maintenance was met by interplay of content- and task-specific modules in a frontoparietal network...
  50. pmc On the capacity of attention: its estimation and its role in working memory and cognitive aptitudes
    Nelson Cowan
    Department of Psychological Sciences, University of Missouri, 18 McAlester Hall, Columbia, MO 65211, USA
    Cogn Psychol 51:42-100. 2005
    ..So does digit span in children too young to rehearse...
  51. ncbi Cortical capacity constraints for visual working memory: dissociation of fMRI load effects in a fronto-parietal network
    David E J Linden
    Max Planck Institut für Himforschung, Deutschordenstrasse 46, D 60528 Frankfurt, Germany
    Neuroimage 20:1518-30. 2003
    ..These results indicate that at least two distinct cortical subsystems are recruited for visual WM, and that their interplay changes when the capacity limit is reached...
  52. ncbi Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning
    Christoph Kellendonk
    Center for Neurobiology and Behavior, College of Physicians and Surgeons, Columbia University, 1051 Riverside Drive, New York, New York 10032, USA
    Neuron 49:603-15. 2006
    ..We found that D2R overexpression in the striatum impacts dopamine levels, rates of dopamine turnover, and activation of D1 receptors in the prefrontal cortex, measures that are critical for working memory...
  53. ncbi The relationship between performance and fMRI signal during working memory in patients with schizophrenia, unaffected co-twins, and control subjects
    Katherine H Karlsgodt
    Department of Psychology, UCLA, Los Angeles, CA 90095 1563, USA
    Schizophr Res 89:191-7. 2007
    ..Further, this study offers preliminary evidence that the relationship between behavior and physiology in schizophrenia may be heritable...
  54. pmc Attention effects during visual short-term memory maintenance: protection or prioritization?
    Michi Matsukura
    Department of Psychology, University of Iowa, Iowa City, Iowa 52242 1407, USA
    Percept Psychophys 69:1422-34. 2007
    ..The results of the experiments were consistent with the first of these possibilities, suggesting that attention can serve to protect VSTM representations while they are being maintained...
  55. pmc Delays in neural processing during working memory encoding in normal aging
    Theodore P Zanto
    Department of Neurology, W M Keck Foundation Center for Integrative Neuroscience, University of California San Francisco, San Francisco, CA 94158, USA
    Neuropsychologia 48:13-25. 2010
    ..These results suggest that the presence of both generalized feature-based and feature-specific deficits in the speed of selective encoding of information contributes to WM performance deficits in older adults...
  56. ncbi Distributing versus focusing attention in visual short-term memory
    Tal Makovsik
    Harvard University, Cambridge, Massachusetts, USA
    Psychon Bull Rev 14:1072-8. 2007
    ..We propose that the robustness of VSTM is influenced by whether attention is focused or distributed in VSTM...
  57. pmc The representation of abstract task rules in the human prefrontal cortex
    Sara L Bengtsson
    Wellcome Trust Centre for Neuroimaging, University College London UCL, 12 Queen Square, London WC1N 3BG, UK
    Cereb Cortex 19:1929-36. 2009
    ..We argue that the ventral prefrontal cortex is specialized for handling conditional rules regardless of how the task rules were established...
  58. ncbi Recruitment of parvalbumin-positive interneurons determines hippocampal function and associated behavior
    Elke C Fuchs
    Department of Clinical Neurobiology, University Hospital of Neurology, IZN, Im Neuenheimer Feld 364, 69120 Heidelberg, Germany
    Neuron 53:591-604. 2007
    ..These findings directly show the effects of insufficient recruitment of fast-spiking cells at the network and behavioral level and demonstrate the role of this subpopulation for working and episodic-like memory...
  59. ncbi Shared and distinct neurophysiological components of the digits forward and backward tasks as revealed by functional neuroimaging
    Brooke K Gerton
    Unit on Integrative Neuroimaging, Clinical Brain Disorders Branch, Intramural Research Program, National Institute of Mental Health, NIH, Bethesda, MD 20892 1365, USA
    Neuropsychologia 42:1781-7. 2004
    ....
  60. ncbi Specialization in the left prefrontal cortex for sentence comprehension
    Ryuichiro Hashimoto
    Department of Cognitive and Behavioral Science, Graduate School of Arts and Sciences, The University of Tokyo, Komaba, 3 8 1 Komaba, Meguro ku, Tokyo 153 8902, Japan
    Neuron 35:589-97. 2002
    ..These results support the proposal of specialized systems for sentence comprehension in the left prefrontal cortex...
  61. ncbi Binding in short-term visual memory
    Mary E Wheeler
    Department of Psychology, Princeton University, New Jersey 08544, USA
    J Exp Psychol Gen 131:48-64. 2002
    ....
  62. ncbi The representation of instructions operates like a prepared reflex: flanker compatibility effects found in first trial following S-R instructions
    Oshrit Cohen-Kdoshay
    Department of Behavioral Sciences ans Zlotowski Center for Neuroscience, Ben Gurion University of the Negev, Beer Sheva, Israel
    Exp Psychol 56:128-33. 2009
    ..The authors show that the FCE was present in the first trial immediately following the instructions, thus providing unequivocal support for the PR metaphor...
  63. ncbi The relationship between antisaccades, smooth pursuit, and executive dysfunction in first-episode schizophrenia
    Samuel B Hutton
    Department of Psychology, University of Sussex, Brighton, UK
    Biol Psychiatry 56:553-9. 2004
    ....
  64. ncbi Practitioner review: short-term and working memory impairments in neurodevelopmental disorders: diagnosis and remedial support
    Susan E Gathercole
    Department of Psychology, University of Durham, UK
    J Child Psychol Psychiatry 47:4-15. 2006
    ..The memory impairments associated with a range of neurodevelopmental disorders (Down's syndrome, Williams syndrome, Specific Language Impairment, and attentional deficits) are discussed...
  65. pmc Representation of attended versus remembered locations in prefrontal cortex
    Mikhail A Lebedev
    Laboratory of Systems Neuroscience, National Institute of Mental Health, Bethesda, Maryland, USA
    PLoS Biol 2:e365. 2004
    ..Instead, PF's delay-period activity probably contributes more to the process of attentional selection...
  66. pmc Early top-down control of visual processing predicts working memory performance
    Aaron M Rutman
    University of California, San Francisco, CA 94158, USA
    J Cogn Neurosci 22:1224-34. 2010
    ..These results contribute to our evolving understanding of the mechanistic overlap between attention and memory...
  67. ncbi Is the prefrontal cortex necessary for establishing cognitive sets?
    James B Rowe
    Department of Clinical Neurosciences, Cambridge University, Cambridge CB2 2QQ, United Kingdom
    J Neurosci 27:13303-10. 2007
    ..The results suggest that the left rostral prefrontal cortex is indeed required for establishing a cognitive set but that the essential function is to support the functional connectivity among the task-related regions...
  68. ncbi Frontal lobe mechanisms that resolve proactive interference
    David Badre
    Department of Psychology and Neurosciences Program, Stanford University, Stanford, CA 94305, USA
    Cereb Cortex 15:2003-12. 2005
    ..Collectively, these results serve to specify and constrain proposed models of PI resolution...
  69. ncbi A functional magnetic resonance imaging study of working memory abnormalities in schizophrenia
    Matthew R Johnson
    Olin Neuropsychiatry Research Center, The Institute of Living at Hartford Hospital, Hartford, CT, USA
    Biol Psychiatry 60:11-21. 2006
    ..We examined neural function changes at several WM loads to derive a more complete picture of WM dysfunction in schizophrenia...
  70. ncbi Functional frontoparietal connectivity during short-term memory as revealed by high-resolution EEG coherence analysis
    Claudio Babiloni
    Dipartimento di Fisiologia Umana e Farmacologia, Universita degli Studi di Roma La Sapienza, Rome, Italy
    Behav Neurosci 118:687-97. 2004
    ..In conclusion, frontoparietal connectivity would optimize "representational" memory during STM. In this context, the frontal areas would increase their influence on parietal areas for memory retention...
  71. ncbi Meta-analyzing left hemisphere language areas: phonology, semantics, and sentence processing
    M Vigneau
    Groupe d Imagerie Neurofonctionnelle, UMR 6194, CNRS CEA Caen and Paris 5 Universities, GIP Cyceron, Boulevard Henri Becquerel, BP 5229, 14074 Caen Cedex, France
    Neuroimage 30:1414-32. 2006
    ..These results argue for large-scale architecture networks rather than modular organization of language in the left hemisphere...
  72. ncbi Spatial working memory and planning ability: contrasts between schizophrenia and bipolar I disorder
    Johanna C Badcock
    School of Psychiatry and Clinical Neurosciences, University of Western Australia Centre for Clinical Research in Neuropsychiatry, Graylands Hospital, Perth, Australia
    Cortex 41:753-63. 2005
    ....
  73. pmc Striatal dopamine and working memory
    Susan M Landau
    Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720 3190, USA
    Cereb Cortex 19:445-54. 2009
    ..These results provide new evidence that striatal dopaminergic function is related to PFC-dependent functions, particularly brain activation and behavioral performance during WM tasks...
  74. ncbi Speed selectivity in visual short term memory for motion
    D J McKeefry
    Division of Optometry, School of Life Sciences, University of Bradford, Bradford BD7 1DP, UK
    Vision Res 47:2418-25. 2007
    ..attributes are important in the storage of information about the speed of moving grating stimuli in visual short term memory (VSTM)...
  75. ncbi Directing spatial attention in mental representations: Interactions between attentional orienting and working-memory load
    Jöran Lepsien
    Brain and Cognition Laboratory, Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
    Neuroimage 26:733-43. 2005
    ..Orienting of spatial attention to the contents of working memory activated posterior parietal cortex bilaterally, the insula, and lateral and medial frontal cortices...
  76. ncbi Heat stress, plasma concentrations of adrenaline, noradrenaline, 5-hydroxytryptamine and cortisol, mood state and cognitive performance
    Terry McMorris
    Centre for Sports Science and Medicine, University College Chichester, College Lane, Chichester, West Sussex PO19 6PE, UK
    Int J Psychophysiol 61:204-15. 2006
    ....
  77. ncbi Oscillations in the alpha band (9-12 Hz) increase with memory load during retention in a short-term memory task
    Ole Jensen
    Brain Research Unit, Low Temperature Laboratory, Helsinki University of Technology, Otakaari 3A, 02015 HUT, Finland
    Cereb Cortex 12:877-82. 2002
    ..Hypotheses concerning the role of alpha band activity in working memory are discussed...
  78. ncbi A short review of slow phase synchronization and memory: evidence for control processes in different memory systems?
    Wolfgang Klimesch
    Department of Physiological Psychology, University of Salzburg, Austria
    Brain Res 1235:31-44. 2008
    ..The hypothesis, suggested here is that theta and upper alpha reflect these processes which can be best studied when analyzing phase...
  79. ncbi Modality-specific processing streams in verbal working memory: evidence from spatio-temporal patterns of brain activity
    D S Ruchkin
    Department of Physiology, School of Medicine, University of Maryland, Baltimore 21201 1559, USA
    Brain Res Cogn Brain Res 6:95-113. 1997
    ....
  80. ncbi Distributed cortical systems in visual short-term memory revealed by event-related functional magnetic resonance imaging
    Matthias H J Munk
    Max Planck Institut für Hirnforschung, Deutschordenstrasse 46, D 60528 Frankfurt, Germany
    Cereb Cortex 12:866-76. 2002
    ..These modulations confirmed a posterior-anterior and right-left dissociation for spatial versus non-spatial memory and revealed that conjunction memory does not rely on a linear addition of the component processes...
  81. ncbi A within-subjects, within-task demonstration of intact spatial reference memory and impaired spatial working memory in glutamate receptor-A-deficient mice
    Wolfram B Schmitt
    Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
    J Neurosci 23:3953-9. 2003
    ....
  82. ncbi Evidence for quantitative domain dominance for verbal and spatial working memory in frontal and parietal cortex
    Henrik Walter
    Department of Psychiatry, University of Ulm, Germany
    Cortex 39:897-911. 2003
    ..The concept of domain dominance is discussed in the light of recent theories of prefrontal cortex function...
  83. ncbi Working memory controls involuntary attention switching: evidence from an auditory distraction paradigm
    Stefan Berti
    Institut für Allgemeine Psychologie, Universitat Leipzig, Seeburgstr 14 20, D 04103 Leipzig, Leipzig, Germany
    Eur J Neurosci 17:1119-22. 2003
    ..The present data suggest that working memory is able to coordinate the maintenance of distractibility and the focus on the task at hand...
  84. ncbi Event-related potential measures of visual working memory
    Trafton W Drew
    Department of Psychology, University of Oregon, Eugene 97403 1227, USA
    Clin EEG Neurosci 37:286-91. 2006
    ..This component is sensitive to an individual's working memory capacity and may provide a window into the operations of this central cognitive construct...
  85. ncbi Effects of neuromodulation in a cortical network model of object working memory dominated by recurrent inhibition
    N Brunel
    LPS, Ecole Normale Superieure, 24 rue Lhomond, 75231 Paris Cedex 05, France
    J Comput Neurosci 11:63-85. 2001
    ..The present study therefore points to several mechanisms that enhance the signal-to-noise ratio in working memory states. These mechanisms could be implemented in the prefrontal cortex by dopaminergic projections from the midbrain...
  86. pmc The role of working memory representations in the control of attention
    Geoffrey F Woodman
    Department of Psychology, Vanderbilt University, Nashville, TN 37240 1103, USA
    Cereb Cortex 17:i118-24. 2007
    ....
  87. ncbi Functional-anatomic correlates of control processes in memory
    Randy L Buckner
    Department of Psychology, Howard Hughes Medical Institute at Washington University, St Louis, Missouri 63130, USA
    J Neurosci 23:3999-4004. 2003
  88. ncbi The organization of recent and remote memories
    Paul W Frankland
    Program in Integrative Biology, Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1XB
    Nat Rev Neurosci 6:119-30. 2005
    ..However, recent studies have begun to shed light on how remote memories are organized in the cortex, and the molecular and cellular events that underlie their consolidation...
  89. ncbi Working memory in primate sensory systems
    Tatiana Pasternak
    Department of Neurobiology and Anatomy, Center for Visual Science, Box 603, University of Rochester, Rochester, New York 14642, USA
    Nat Rev Neurosci 6:97-107. 2005
    ..These circuits seem to have a dual function: precise sensory encoding and short-term storage of this information. New results provide insights into how activity in these circuits represents the remembered sensory stimuli...
  90. ncbi Evidence that autobiographic memory retrieval does not become independent of the hippocampus: an fMRI study contrasting very recent with remote events
    P V Rekkas
    Department of Diagnostic Radiology, Yale University School of Medicine, TAC MRRC N127, P O Box 208042, New Haven, CT 06520 8042, USA
    J Cogn Neurosci 17:1950-61. 2005
    ....
  91. ncbi Prefrontal selection and medial temporal lobe reactivation in retrieval of short-term verbal information
    Katsuyuki Sakai
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12 Queen Square, London WC1N 3BG, UK
    Cereb Cortex 14:914-21. 2004
    ..By contrast, the activity in the middle frontal gyrus did not differ between the two conditions. Taking these results together, we have shown the double dissociation between the PFC and MTL in memory retrieval...
  92. ncbi Spatial working memory capacity in unilateral neglect
    Paresh Malhotra
    Division of Neuroscience, Imperial College, Charing Cross Hospital Campus, London W6 8RF, UK
    Brain 128:424-35. 2005
    ..These findings demonstrate that an impairment in SWM capacity can contribute to the neglect syndrome in patients with stroke involving regions within the right parietal lobe and insula...
  93. ncbi External and body-centered frames of reference in spatial memory: evidence from touch
    Susanna Millar
    Department of Experimental Psychology, University of Oxford, Oxford, England
    Percept Psychophys 66:51-9. 2004
    ..The discussion considers theoretical and practical implications of the results...
  94. ncbi Abnormal gaze strategies during problem solving in Parkinson's disease
    T L Hodgson
    Division of Neuroscience and Psychological Medicine, Faculty of Medicine, Imperial College, Charing Cross Hospital Campus, 10th Floor East Wing, St Dunstans Road, London W6 8RP, UK
    Neuropsychologia 40:411-22. 2002
    ..This pattern suggests that the patients had difficulty in encoding and/or maintaining current goals during problem solving, consistent with a role for fronto-striatal circuits in mechanisms of working memory and attention...
  95. pmc Impaired spatial working memory but spared spatial reference memory following functional loss of NMDA receptors in the dentate gyrus
    B Niewoehner
    Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
    Eur J Neurosci 25:837-46. 2007
    ....
  96. ncbi Electrophysiological measures of maintaining representations in visual working memory
    Andrew W McCollough
    University of Oregon, Eugene 97403 1227, USA
    Cortex 43:77-94. 2007
    ..Together, these results appear to indicate an electrophysiological index of the maintained representations in visual WM...
  97. pmc Practice-related improvement in working memory is modulated by changes in processing external interference
    Anne S Berry
    Department of Neurology, W M Keck Foundation Center for Integrative Neuroscience, University of California, San Francisco, 600 16th St, Genentech Hall, MC2240 Rm N472J, San Francisco, CA 94158, USA
    J Neurophysiol 102:1779-89. 2009
    ....
  98. ncbi A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure
    A Bichler
    Biology Core Curriculum, University of Wisconsin, Madison, WI, USA
    Amino Acids 31:471-6. 2006
    ..We investigated the combined effects of Red Bull's two active ingredients, caffeine and taurine, on short term memory. Studies on the effects of these two neuromodulators on memory have yielded mixed results, and their ..
  99. ncbi Temporal dynamics of brain activation during a working memory task
    J D Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA
    Nature 386:604-8. 1997
    ..We used the temporal resolution of this technique to examine the dynamics of regional activation, and to show that prefrontal cortex along with parietal cortex appears to play a role in active maintenance...
  100. ncbi A comparison of auditory and visual distraction effects: behavioral and event-related indices
    S Berti
    Institut für Allgemeine Psychologie, Universitat Leipzig, Seeburgstr 14 20, D 04103, Leipzig, Germany
    Brain Res Cogn Brain Res 10:265-73. 2001
    ..Moreover, the results suggest that in both tasks irrelevant deviants were detected by modality-specific processes which caused an attention shift...
  101. ncbi Functional Interaction Between NMDA and mGlu5 Receptors: Effects on Working Memory, Instrumental Learning, Motor Behaviors, and Dopamine Release
    Houman Homayoun
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuropsychopharmacology 29:1259-69. 2004
    ..By extension, these results suggest that pharmacological potentiation of mGlu5 receptors may ameliorate the cognitive and other behavioral abnormalities associated with NMDA receptor deficiency...

Research Grants67

  1. The Functional Neurobiology of Cannabinoids in Brain
    EDWARD FRENCH; Fiscal Year: 2006
    ..abstract_text> ..
  2. Memory, Thiamine Levels, and Brain Structure in Heart Failure
    MARY ANN WOO; Fiscal Year: 2010
    ....
  3. Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical Illness
    Eva Szigethy; Fiscal Year: 2009
    ..abstract_text> ..
  4. Novel therapy for monoamine neurotransmitter deficiency in PKU
    Cary O Harding; Fiscal Year: 2013
    ..Our goal is to thoroughly evaluate these novel therapeutic approaches in Pahenu2 mice and to choose specific interventions for a future clinical trial in humans with PKU. ..
  5. Mechanisms of Ubiquitin Trafficking in Neurons
    Michael C Wooten; Fiscal Year: 2013
    ..mice causes oxidative stress leading to Alzheimer-like characteristics such as tau-phosphorylation, loss of short term memory and synaptic plasticity, reduced serum BDNF, depression, anxiety, along with accumulation of highly ..
  6. CB1 Receptor Regulation by Cannabinoid Receptor Interacting Protein CRIP1a
    DANA E contact SELLEY; Fiscal Year: 2010
    ....
  7. Noncoding RNAs as epigenomic modulators in Alzheimer's Disease
    CLAES ROBERT WAHLESTEDT; Fiscal Year: 2010
    ..However, these genetic causes are at least in part atypical (nonconventional), and we therefore argue that so-called "epigenetic/epigenomic" causes must be considered. ..
  8. CRCNS: Gamma Rhythms and Cell Assemblies
    Nancy Kopell; Fiscal Year: 2013
    ..They are believed to be important for a range of functions, including attention, early sensory processing, short term memory, motor activity...
  9. Defining the epitope in antiNMDA receptor encephalitis
    DAVID ROBINSON LYNCH; Fiscal Year: 2010
    ..Through understanding of this process, the proposal may facilitate therapies for preventing damage in this disorder and a basic understanding of other neurologic disorders such as stroke. ..
  10. RNAi therapy for Huntingtons disease: safety & efficacy in the nonhuman primate
    Jodi L McBride; Fiscal Year: 2010
    ..Testing the utility of RNA interference in a nonhuman primate model of HD is a necessary and key step towards its potential use in the clinic. ..
  11. RNAi therapy for Huntingtons disease: safety &efficacy in the nonhuman primate
    Jodi L McBride; Fiscal Year: 2013
    ..The studies proposed here, along with the didactic and applied training, will be invaluable in assisting my transition from a post-doctoral fellow to an independent investigator. ..
  12. A Familial Study of Severe Phonology Disorders
    Barbara A Lewis; Fiscal Year: 2012
    ..This project will provide life-span data that is needed to determine full significance of early SSD for the later functioning of this population and identify factors that influence adolescent/young adult outcomes. ..
  13. Ethanol effects on retinoic acid function in embryo hippocampus
    Joseph L Napoli; Fiscal Year: 2013
    ....
  14. Arm Motor Rehabilitation, Entertainment and Cognition System for the Elderly
    Grigore C Burdea; Fiscal Year: 2013
    ..The approach can be extended to other patient populations with motor and cognitive co-morbidities acute, sub-acute and chronic, adult and paediatric. ..
  15. NEURAL MECHANISMS OF CUTANEOUS SPATIAL INTEGRATION
    Esther P Gardner; Fiscal Year: 2012
    ....
  16. Core Facilities for Neurobiology at Brandeis
    Michael Rosbash; Fiscal Year: 2013
    ..abstract_text> ..
  17. In vivo methods for preclinical analysis of cognitive therapies for schizophrenia
    JONATHAN MAX LEVENSON; Fiscal Year: 2010
    ..The cognitive deficits in schizophrenia include impaired attention and disruption of an essential type of short term memory called working memory...
  18. Regulatory RNAs as mediators and biomarkers in Alzheimer's Disease
    CLAES ROBERT WAHLESTEDT; Fiscal Year: 2012
    ..Understanding the mechanisms by which BACE1 is regulated may reveal important insights into the pathogenesis of AD, and lead to the development of novel therapeutics and AD biomarkers. ..
  19. Neuroimaging Correlates of Cocaine Reinforcement for Cognitive Performance
    Samuel A Deadwyler; Fiscal Year: 2013
    ..Primarily the Program will focus on the effects of cocaine on cognition in nonhuman primates which serves as the final testbed for candidate drugs that can lead to therapeutic treatment of cocaine abusers. ..
  20. Remediation of Word Processing and Short-Term Memory Deficits in Aphasia
    Nadine Martin; Fiscal Year: 2009
    ..The efficacy of the treatment will be examined with probes of acquisition and maintenance in a multiple baseline across multiple stimuli design, and with comparisons of pre- and post-test ..
  21. The Neuropsychology of Memory
    Larry R Squire; Fiscal Year: 2013
    ....
  22. Genome-Wide RNAi Screen for Genes Involved in Learning
    Ronald L Davis; Fiscal Year: 2010
    ....
  23. Alcohol-Chemokine Interactions and Neurotransmission
    Donna L Gruol; Fiscal Year: 2010
    ..Taken together, these studies will provide important new information that will significantly advance our understanding of the role of neuroimmune factors in alcoholism. ..
  24. Genetic characterization of long-term memory in Caenorhabditis elegans
    Rachel L Kaletsky; Fiscal Year: 2013
    ..This research aims to elucidate novel genetic factors that are involved in normal long-term memory and neurodegeneration, which may lead to therapies that improve cognitive abilities with age. ..
  25. Ca2+ Stimulation of MAP Kinase and Neuroplasticity
    Daniel R Storm; Fiscal Year: 2013
    ..This project focuses on molecular mechanisms underlying memory consolidation and persistence. Consequently, this research may identify new drug target sites that can be exploited to enhance long-term and short-term memory. ..
  26. CB1 Mediation of Cerebellum Versus Forebrain-Dependent Associative Learning
    PATRICK DAVID SKOSNIK; Fiscal Year: 2013
    ....
  27. Implicit Learning in Osteocyte Network under Mechanical Loading
    X Edward Guo; Fiscal Year: 2010
    ..e., habituation, sensitization, and classical conditioning, in in vitro osteocytic networks. The mechanotransduction mechanisms have a great importance in understanding the etiology of osteoporosis and preventing bone loss in space. ..
  28. Human Fronto-Parietal Networks for Visual Attention and Memory
    David C Somers; Fiscal Year: 2013
    ..As the specific contributions of different brain regions are characterized, research can focus on identifying particular network subcomponents that may be differentially impaired in different clinical populations. ..
  29. Memory and Brain Structure in Adolescents with Single Ventricle Heart Disease
    NANCY ANN PIKE; Fiscal Year: 2013
    ....
  30. Imaging neural activity in the rat frontal cortex during short-term memory
    Benjamin B Scott; Fiscal Year: 2013
    ..Recording in two regions during this task should allow me to critically evaluate the relationship between these two proposed forms of cortical dynamics and short-term memory. ..
  31. Novel serotonergic, pro-cognitive antipsychotic therapies
    Silvana Leit; Fiscal Year: 2012
    ..symptoms of schizophrenia include impaired attention and disruption of working memory, an essential type of short term memory. These fundamental cognitive processes are critical for the performance of day-to-day activities, and their ..
  32. Speech perception, acoustic variability and time: normal and impaired listeners
    Bob McMurray; Fiscal Year: 2013
    ....
  33. Behavioral and neural mechanisms of visual short-term memory
    WHEE KY MA; Fiscal Year: 2013
    ..The resulting network will be entirely based on the uncertainty model but exhibit the appearance of a capacity limit. It will serve as a basis for physiological tests. ..
  34. Learning-dependent plasticity and mnemonic encoding in parieto-frontal networks
    Arup Sarma; Fiscal Year: 2013
    ..Thus, the knowledge gained from studying the neural basis of learning and memory will likely shed light onto valuable next-generation treatments for neurological and cognitive disorders. ..
  35. Effects of Statins on the Neurobiology of Learning and Memory Across the Lifespan
    Carolyn L Pytte; Fiscal Year: 2012
    ..Data on neurogenesis and survival, in conjunction with functional consequences, will lead to new hypotheses about the role of the cholesterol synthesis pathway in critical aspects of neural development and plasticity. ..
  36. Mechanistic Determinants of Pacing-induced Cardiac Memory
    Michael R Rosen; Fiscal Year: 2010
    ..Rather than being reductionist, the approach attempts to synthesize information so that we can better comprehend and impact on a clinically important problem. ..
  37. Conformational Change in Molecular Biology
    Martin Karplus; Fiscal Year: 2011
    ..We will study how these motors work and employ the results to find inhibitors for ATP synthesis in the mitochondria, a suggested treatment of cancer, and to interpret the effect of replication errors in DNA synthesis by polymerases. ..
  38. MEMORY SYSTEMS OF THE MAMMALIAN BRAIN
    Larry R Squire; Fiscal Year: 2013
    ....
  39. Linguistic Processes in Sentence Comprehension and Reading
    ROGER PHILIP LEVY; Fiscal Year: 2013
    ..abstract_text> ..
  40. Adaptive allocation of attentional gain
    John Serences; Fiscal Year: 2013
    ..This knowledge will aid in the development of more objective tests for common disorders of attention - such as attention deficit disorder - so that diagnosis can proceed with greater precision and interventions can be started earlier. ..
  41. Functional Analysis of Sleep Homeostasis in Drosophila
    Paul J Shaw; Fiscal Year: 2013
    ....
  42. Medial temporal lobe contributions to short-term memory in amnesia
    Elizabeth Race; Fiscal Year: 2013
    ....
  43. Cognitive impact of iterictal spikes in temporal lobe epilepsy
    JONATHAN KLEEN; Fiscal Year: 2013
    ..Our ultimate goal is to discern whether interictal spikes have the potential to significantly impact patient quality of life, and consequently if their presence should be factored in to clinical treatment decisions. ..
  44. Aging and Emotional Memory
    Mara Mather; Fiscal Year: 2013
    ..Our studies examine whether their suppression deficits are greater when stimuli priority is determined by top-down goals or by bottom-up salience and how suppression deficits affect long-term memory. ..
  45. ENCODING AND REMEMBERING EVENTS ACROSS THE LIFE SPAN
    Jeffrey M Zacks; Fiscal Year: 2012
    ..The proposed research investigates how the mind and brain do this chunking, how it changes as people age, and what interventions might improve its effectiveness. ..
  46. Early Development with Williams or Down Syndrome
    Carolyn B Mervis; Fiscal Year: 2013
    ..abstract_text> ..
  47. Computational Neural and Behavioral Studies of Competition-Dependent Learning
    Kenneth A Norman; Fiscal Year: 2013
    ..g., when treating phobias or post-traumatic stress disorder). ..
  48. Language Processing in Children with Cochlear Implants
    Richard G Schwartz; Fiscal Year: 2013
    ..The project is health related in that it will lead to novel, computer-based methods for language assessment and habilitation directed towards vocabulary knowledge and processing for these children. ..
  49. Memory Processing and Cortical Plasticity
    Anthony A Wright; Fiscal Year: 2011
    ..g., PTSD) for targeted treatment and evaluation. ..
  50. Electrophysiological Assessment of Cannabinois Receptors
    Samuel A Deadwyler; Fiscal Year: 2012
    ..The outcomes of these studies will define not only what type of neural processes are susceptible to disruption by cannabinoid use, but also when the encoding of information by those processes is susceptible to such influence. ..
  51. CRCNS: Attentional Selection and Perceptional Organization
    Ernst Niebur; Fiscal Year: 2012
    ..The insight gained from this project will contribute to the understanding of the neural basis of cognitive disorders such as dyslexia and hemi-neglect. ..
  52. Cognitive Processing and Sentence Comprehension in SLI
    James W Montgomery; Fiscal Year: 2013
    ....
  53. Understanding delay discounting in cigarette smokers
    AMY ODUM; Fiscal Year: 2013
    ..As a result, we may help to develop new strategies to prevent people from starting to smoke, as well as to help them quit successfully if they already smoke. ..
  54. Advanced MRI Techniques in Traumatic Brain Injury
    Christine L Mac Donald; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Accurate diagnostics like DTI and resting-state fMRI could improve triage, stratification for clinical trials, rehabilitation and life-planning, substantially impacting public health. ..
  55. Effects of Argument Structure &Processing Load on Sentence Processing in Aphasia
    Nadine Martin; Fiscal Year: 2012
    ..Clinically, these studies will provide evidence that syntactic priming treatments effectively improve sentence production in agrammatic aphasia, even in more severe cases when production is limited to 1-3 word utterances. ..
  56. PRINCIPLES OF REINFORCEMENT
    Peter Killeen; Fiscal Year: 2001
    ..The value of this RSA accrues both to the PI in terms of the new quantitative skills he will acquire, and to the field in the new interpretation of memory and performance he offers. ..
  57. Mechanisms and Taxonomy of Visual Attention
    Barbara A Dosher; Fiscal Year: 2012
    ..This analysis can additionally constrain process models of attention in normal observers and may suggest constraints on the relevant properties of neurological models of attention. ..
  58. Understanding cognitive development in infancy: Attention and visual short-term m
    Lisa M Oakes; Fiscal Year: 2013
    ..Together, these experiments will add considerably to our understanding of the typical development of this critical cognitive ability. ..
  59. Revealing IPS organization through its role in location and feature processing
    KATHERINE BETTENCOURT; Fiscal Year: 2013
    ....
  60. NE Signal Transduction in Classical Conditioning
    Paula Bickford; Fiscal Year: 2009
    ..Specific Objective 3: Hypothesis: NE and PKA lead to significant downstream alterations in signaling molecules. ..
  61. The Functional Neurobiology of Cannabinoids in Brain
    EDWARD FRENCH; Fiscal Year: 2001
    ..abstract_text> ..
  62. MODULATION OF NEUROTRANSMITTER RELEASE BY CANNABINOIDS
    Andrew Gifford; Fiscal Year: 2002
    ..Furthermore, these experiments will give information on the mode of action of cannabinoid antagonists and could suggest novel therapeutic uses for this new class of compounds. ..
  63. ETHANOL AND AMNESIC DRUGS IN P AND NP RATS
    GALEN WENGER; Fiscal Year: 2000
    ..If they are, it will provide additional potential insight into the role that cognitive processes play in alcohol dependence. ..
  64. Contribution of emotional memory to social cognition in aging
    Haiyin Chen; Fiscal Year: 2007
    ..Understanding its normal function and changes between the young and old amygdala will be a critical step toward finding effective treatments for these diseases. [unreadable] [unreadable] [unreadable]..
  65. NEURONAL INTEGRATION IN CEREBELLAR SYSTEMS
    Vlastislav Bracha; Fiscal Year: 2004
    ....
  66. NEUROLOGY OF MEMORY
    Stuart Zola; Fiscal Year: 2002
    ..A finding that hippocampal damage effects spatial memory to the same degree as do larger lesions would suggest that the hippocampus has a special role in spatial memory. ..
  67. Visual Short Term Memory in Infancy
    LISA OAKES; Fiscal Year: 2003
    ..These experiments will provide an important foundation for the study of short-term memory in infancy. ..